Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| PP2Cc_SM00332 | 30-332 | 3.7e-33 | 108.1 | In-house | 5-257 (274) | alignment | |||
Range on Protein: 30-332
Range on HMM: 5-257/274.0
GSASNRSYSADGKGTESHPPEDSWLKFRS---ENNCFLYGVFNGYDGNRVTNFVAQRLSaELLLGQLNAEHA--EADVRRVLLQAFDVVERSFLESIDDA
|| .. ||. . . .. .. || . . |.. ..||| | |..| .||...| | | .|. . | || ..| .|| .. .||. .
gsnlglsygkssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklp.ealkeelkkkkdeleddveealkkaflstdeeileeeqsk
LAEKaslqsqlpegvpqhqlppqyqkilerlktlereISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVdglqVTQLNVDHTTENEDELFRLSQLGLd
. |. . |..||||.| ...||||||| || ||.. ..|| |||..|.|||. |... |
elen.................................alsGstavvallkkedlyvanvGDSravlcrngk....avqlsvdhkpedederkRikkagg.
agKIKQVGIICGQESTRRIGDYKVKYGYtdidllsAAKSKPIIAEPEIHGAQPlDGVTGFLVLMSEGLYKaleaahgpGQANQEIAAMIDTEFAKQ--TS
.... . .|....| .||...| |.. |.|||... . . . ||.|.| ||. |||. .. ||. .
..vvekgrvngglavsrafGdhflkknk.......klkepyitaepdvkvvtl.tsedeflilaSDGlwd........vlsnqevvdivrkllakgktnd
LDAVAQAVVD
...|. ...
pqeaaellde
|
|||||||||
| subfamily_TAB1_pd | Subfamily TAB1 | 31-366 | 8.1e-152 | 497.8 | In-house | 1-332 (333) | alignment | ||
Range on Protein: 31-366
Range on HMM: 1-332/333.0
SASNRSYSadgkgTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKAS
|.|||.|| .|.|. ||....|..||...||.||.|||||....||.|||.|||||.||..|.|||.|..||..||. |||.||||||||||||..
svsnrrys.....kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekdd
LQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVdGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQ
|||||||||....| ||.. .|||..||.|||||..||||...||||||||||..||||.|... .|.||.|||||.|||||.||..||||. .||.
lqsqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke.sekvkqLsvdHttdNedEllRlkdLGldieqikr
VGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQE-IAAMIDTEFAKQTSLDAVAQA
.......|.||.|||||||.||.|.|.||.||..|.||||.|.||.|.|..|.||||||.|.||.||...||...|.| |.....||..||..|..||||
nkrlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdvAqa
VVDRVKRIHSDTFASGG-ERARFCPRHEDMTLLVRNFG
|||.|||.|.|...|.. |||..|....||||||..|.
vvdkvkrkHkdaylssaseravicrkrddmtllvlkfe
|
|||||||||
| 0034914 | PP2C-like | 32-365 | 6.9e-37 | 120.0 | In-house | 19-290 (295) | alignment | ||
Range on Protein: 32-365
Range on HMM: 19-290/295.0
ASNRSYSADGKGTeSHPPEDSWLKFRS----ENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLG----QLNAEHAEADVRRVLLQAFDVVERSFLESIDD
. |...|. .| ... ||..| ... .....|.|||.|. | .. ......| .|| .|.... . |....| .|| ... .|| . .
lllrvgvasdqGr.rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelall
AlaekaslqsqlpegvpqhqlppqyqkilerlktlEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGL
. . .|. ||||.. .||||||||| ||.|... ...||.|||. ||.| |. ..|
r..................................pelagsGtTavvalirgnklyvanvGDSravllrng....elvqltvdhkpvnelererilsagg
dagkIKQVGIICGQ-ESTRRIGDYKVKYGYTDidllsAAKSKPIIAEPEIHgAQPLD-GVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQT
. . | ..|. || .||. |. ... ... ...|||... ..|. . ||.|.|.||.. |. |.||.... . .||..
....avshgrvngvlavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls........neeivdivrsllakgl
SLDAVAQAVVDRVKRihsdtfasggerarfCPRHEDMTLLVRNF
.|...|...||.. . . ....| .| .
dleeaaeeLvdlAla...............rgsrDNiTvvvvrl
|
|||||||||
| 0049733 | PP2C-like | 43-362 | 4.8e-19 | 61.8 | In-house | 12-230 (235) | alignment | ||
Range on Protein: 43-362
Range on HMM: 12-230/235.0
GTESHPPEDSWLKfrsenNCFLYGVFNGYDGNRVTNFVAQRLSAELLlgQLNAEHAEADVRRVLLQAFDVVERSFLESiddalaekaslqsqlpegvpqh
| . ||..| ...|..|..| | .. ......| || .| .|. . |....| .|| ... .||
grvrkvneDavlv.....glllfavaDGhgghaagevasellvetll..elllelllldleealrkaflaaneallel......................
qlppqyqkilerLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKstvDGlQVTQLNVDHTTENEDELFRLSQLGLDAgkikqvGIICGQESTRR
.. . .|. ||||.| ..|||||||| ||.|.. || ...||..||. ||.| |. ..| .. . ||
............alaspelagmgtTavvalldggklyvanvGDsrayllr...dg.klvqltedhspvnelerqriitaggav......rvpgrlaltra
IGDYKVKygytdidllsaakskpiiaePEIHGAQPLDGVtgFLVLMSEGLYKAleaahgpgQANQEIAAMIDTefakqTSLDAVAQAVVDRVKRihsdtf
.||. .| |... . .| ||.|.|.||.. ..||.... . ..|...|...|... .
lGdlllk....................pdvtvlelepgd..flllasDGlwdv........lsdeeivdllrs.....ldleeaaerlvelala......
asggerarfCPRHEDMTLLV
....|..|
.........rggrDNiTvvv
|
|||||||||
| subfamily_PPM1G2_pd | Subfamily PPM1G2 | 45-334 | 3e-20 | 65.3 | In-house | 35-264 (287) | alignment | ||
Range on Protein: 45-334
Range on HMM: 35-264/287.0
ESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRlsaelllgqlnaehaeadvrrvllqafdvversflesIDDALAEKASLQSQLPEGVPQHQL
..| |. |. . .... |..||.|. |..|....... . .|.| |.... | . .. .
DahilenelleksddkslalfavfDGhGGakvakyagkk.....................................likkiakkksfkegaleqilkdaf
PPQYQKILERlKTLEREISgGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQlgldAGKIKQVGIICGQES-TRRI
. ...|. ..|. | . |. |||... ..||||||.| ||.|.... .| .| .|| ..|.| |. . || . ... ..|. . | .
letDeellkd.eklkdesa.GstavvvlikeeklyvanaGDsravlsskg....nvkalsfDhkPqeesekkriia....agGfvelnrvngnLalsral
GDYKVKYGYTdidllSAAKSKPIIAEPEIHgAQPLDGVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQTSLDAVAQAVVDRV
||.. | . . .. . . |.|.. . || . |||| .|.. |. |.|. .. ........||.... ..|.
gDfefkknvk.....kkpeeqivtavPDvl.vkkldeddeflvLaCDGiWDvlt........nkevvdlvrerlvsgakldeiieelldkc
|
|||||||||
| subfamily_PPM1A_pd | Subfamily PPM1A | 54-334 | 7.7e-21 | 67.7 | In-house | 34-264 (282) | alignment | ||
Range on Protein: 54-334
Range on HMM: 34-264/282.0
LKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLL-GQLNAEHAEADVRRVLLQafdVVERSFLEsIDDALAEKASLQSQLPEGvpqhqlppqyqkil
.. . .. .. || | |..|...|.. | ...| .|.....||. .. ... .....||. .|.|. |. . ... .
aslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevke...alrqgfLa.ldeairelstdlktadks..............
erlktlereisgGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGldaGKIKqVGIICGQ-ESTRRIGDYKVKYG
|. ||.... ...|..||.| ||.||. . ... | || ....| |..| | |.. |. ..|. .| .|||..|
............GsTavtvlvsekhliianlGDsRavlcrng....kaaflteDHkpsrpkEkkRieqAG...Gsvv.vsRvnGaLAvsRalGDyeykee
YTdidllSAAKSKPIIAEPEIHGAQPLDGVTgFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQTSLDAVAQAVVDRV
. |... ..||||.. . . . |||| ..|.. |. ..|..... ... ... | .||.|.||.
ee.....kkaeeqlvsaepevtsierseedd.flvlacDGiwDvls........deevvelvrkrlevadeleevakalvdka
|
|||||||||
| subfamily_PPM1H_pd | Subfamily PPM1H | 62-220 | 1.4e-10 | 33.5 | In-house | 62-212 (404) | alignment | ||
Range on Protein: 62-220
Range on HMM: 62-212/404.0
CFLYGVFNGYDGNRVTNFVAQRLsAELLLGQLNAEHA-EADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKIlERlKTLER
. ..|.|.|. |. .. .. | . | .|.. .. . . .. .... .| .. || . .| | . ..| .| .
layfglfDGhaGsgaalvaskll.hkhlkekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqi.ar.ereay
EISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDElfRLSQ
.|.|| |.||..|..|||||| | ||.|... ....| |.| | | . || .
rikGGCtalvalvllgklYvanaGDsRailvrkd....eiiplsadftPeteRq..Rlqe
|
|||||||||
| subfamily_PPM1L_pd | Subfamily PPM1L | 62-297 | 2.6e-10 | 33.0 | In-house | 35-224 (269) | alignment | ||
Range on Protein: 62-297
Range on HMM: 35-224/269.0
CFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAehaeadvrrvllqafdvversflesidD-------AlaekaslqSQLpEGVPQHQLPPQYQKILER
...||.|. |. ..|. ..|. ... .. | . . . .... .|.||.
esffavfdGhGGefaaefakdvlvkaiknkliel...........................dadkentep........inf.sklltdeilsvdekllek
LKTLErEISgGAMAVVAVLLNNKLYVANVGTNRALLCKStvDGLQVtQLNVDHTTENEDELFRLSQLGLD---AGKIKQVGIICgqeSTRRIGDYKVKyg
.|. | .|. |. |..|.. ...| ||||| | .|. .| . | || .. | |. . | | . |.. .| .||| .|
akrae.dia.GttalialvqesdlivanvGdsrGvlydk..rGkai.plsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvla...tsralGdyplk..
ytdidllsaaKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALE
. . .||.|.| . | ||.| |.||. ..
..........dknlviadpdiltfdlddhkpeflilasdGlwdtfs
|
|||||||||
| subfamily_ILKAP_pd | Subfamily ILKAP | 64-120 | 4.5e-06 | 19.0 | In-house | 45-103 (293) | alignment | ||
Range on Protein: 64-120
Range on HMM: 45-103/293.0
LYGVFNGYDGNRVTNFVAQRLSAELL--LGQLNAEHAEADVRRVLLQAFDVVERSFLES
|.||.|. |.| ..|.|..| ..| | . . | .... |...| ... ||.
yyavfdGhaGsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLkl
|
|||||||||
| PPM_PTC7 | 70-333 | 3.4e-43 | 141.0 | In-house | 2-258 (259) | alignment | |||
Range on Protein: 70-333
Range on HMM: 2-258/259.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK--ILERLKT-LER--EI
...... .| . . |...| .|... . . . ... || . . .. . . .| .. ......|. ....| .... . |.||. .. ..
dggasafqgfrksmedahialanless..sgkdsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelksseanteps
SGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKIkQVGIICGQ-ESTRRIGDYKVKYGYTdidllsaa
..|..||||.. ..||||||||. ||.||.| . .||..||...|||| |....| .. ..| ..|. . .| .||.. | ..|
tsGstAvvalitgsklyvAnvGDSravLcrsgnav...kqltedHkpsnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpket........
KSKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDR
......|||.|. .. . . ||.|.|.||. .. . ...|.... .|.|... .|.|....|
eeqlvsaePdisstkidee.defliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiargsedn
|
|||||||||
| PP2C | Protein phosphatase 2C | 70-333 | 7.2e-42 | 136.7 | Pfam-A | 2-254 (255) | alignment | ||
Range on Protein: 70-333
Range on HMM: 2-254/255.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK-ILERLKT-LER--EIS
.......... . . |...| .|... ... .. ... || . . .. ... .| .. .|....|. ...| .... . |.||. .. ...
dvgaselqgarksmedahialknleks..sgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsk
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKikqVGIICGQ-ESTRRIGDYKVKYGYtdidllsaak
|..||||.. ..||||||||..||.||... . ..|..||....||| |....| . .| ..|. . .| .||...| ..
sGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........
SKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAM-IDTEFAKQTSLDAVAQAVVDR
.....|||... .. . . ||.|.|.||. |. . ...|. .. .|.|... .|.|... |.
eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedn
|
|||||||||
| PP2C | Protein phosphatase 2C | 70-333 | 7.2e-42 | 136.7 | In-house | 2-254 (255) | alignment | ||
Range on Protein: 70-333
Range on HMM: 2-254/255.0
GYDGNRVTNFVAQRLSAELLLGQLNAEhaEADVRRVLLQAFDVVERSFLESIDDALAE-KASLQSQLPEG-VPQHQLPPQYQK-ILERLKT-LER--EIS
.......... . . |...| .|... ... .. ... || . . .. ... .| .. .|....|. ...| .... . |.||. .. ...
dvgaselqgarksmedahialknleks..sgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelksskantepsk
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGlqvTQLNVDHTTENEDELFRLSQLGLDAGKikqVGIICGQ-ESTRRIGDYKVKYGYtdidllsaak
|..||||.. ..||||||||..||.||... . ..|..||....||| |....| . .| ..|. . .| .||...| ..
sGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........
SKPIIAEPEIHGAQPLDGvTGFLVLMSEGLYKALEAAHGPGQANQEIAAM-IDTEFAKQTSLDAVAQAVVDR
.....|||... .. . . ||.|.|.||. |. . ...|. .. .|.|... .|.|... |.
eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedn
|
|||||||||
| subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 106-297 | 1.3e-11 | 37.3 | In-house | 77-212 (255) | alignment | ||
Range on Protein: 106-297
Range on HMM: 77-212/255.0
LLQAFDVVERSFlesiddalaekaslqsqlpegvpqhqlppqyqkilerlktLEREISGGAMAVVAVLLNNKLYVANVGTNRALLC-KSTVdglqVTQLN
| .|. .. . || . |. |........| |.|||| |..|| | .. ..|
lkkaykeistqi........................................serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgt....akrls
VDHTTENEDELFRLSQLGldaGKIKQVgiicgQESTRRIGDYKVKYGYTDIDLlsaakSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALE
.|| .|.| |.|.|| |.. . . ..| | | |. | . ....|..... ||.| .|.. .
ldhkPseeseekriselG...Gtvvst.....vvtsrvnGtlavsralGdsfl.....ePfvvpdPdlsqsleiskkdkflilacdGiwdlis
|
|||||||||
| PPM_PTC7_SpoIIE | 125-333 | 9.8e-17 | 54.5 | In-house | 61-229 (230) | alignment | |||
Range on Protein: 125-333
Range on HMM: 61-229/230.0
LAeKASLQsqlpegVPQHQLPPQYQKILERLKTLerEISGGAMAVVAVLLNNK--LYVANVGTNRALLCKStVDGlqvtqlnvdhttenedELFRLsQLG
|| .|.|. | | .... .|.. ..|.|| ||||.. ... |||||.| ...||... .| | .|. ..|
la.fagle......kpeeilrrlnlalaadlede..psssgaTavvalidpstgklyvanaGdsppllvrd.dgg................ereri.vag
LDAGkI-KQVGIICGQ-ESTRRIGDYKVKYgytdidllsaaKSKPIIAEPEiHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMidteFAKQ
. . | . |. . .. .||. ..| . . . |||. . . |.|.. ||.|.|.||. |.... .. .|. . .|..
glps.lGilpgrvfgvlavslapGdlllly...........tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp....aaeg
TSLDAVAQAVVDR
|.....||..
lleDDitllvvrv
|
|||||||||
| subfamily_Choan-PPM-1_pd | Subfamily Choan-PPM-1 | 145-294 | 5.6e-06 | 17.8 | In-house | 115-267 (317) | alignment | ||
Range on Protein: 145-294
Range on HMM: 115-267/317.0
PPQYQKILERLKTLEREISGGAMAVVAVLLNNKLY-VANVGTNRALLC------KSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQ
||.. . . | . | . |. |||||.... . ||| | ||. . |||.| | | || . ..| |. . .|... . | . .
pPkgyvcisrddvptrPldfGttavvavvvdethvvvanaGdaaalvllrdqaghedrdGlsvealsvrhtlrskaerarvaevlpgaahvtedgylail
ESTrrIGDYKVKYGYTD-IDLLsaaKSKPIIAEPEIHGA-QPLDGVTGFLVlMSEGLYK
. . . .|... . || | .||.||.. . | | . .| .|.|.
dea..laayelqltkslGhkll...kraGviadPevrsrvldvdevfavvv.vsdGitd
|
|||||||||
| subfamily_PDP_pd | Subfamily PDP | 157-299 | 3.8e-16 | 52.2 | In-house | 146-302 (398) | alignment | ||
Range on Protein: 157-299
Range on HMM: 146-302/398.0
TLEREISgGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGLDAGK---IKQVGIICGQESTRRIGDYKVKYGY
.|. .| ||.|..|.. ...|.|||.| ||.|... .| ....|. |.|..||.|. |. . . . |.. .. .| ||.. |.
allvals.GacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwse
-TDIDLLSA---AKSKP--------IIAEPEIHGAqPLDGVTGFLVLMSEGLYKALEAA
.. .|. ..| ..||||. . .| . |||| . ||. |.
elqkkvlekaylkvlepkdyktPPYltaePevtsh.klrendkFLvlatDGLwdllsne
|
|||||||||
| subfamily_PPM1E_pd | Subfamily PPM1E | 157-336 | 2.9e-10 | 32.8 | In-house | 95-248 (265) | alignment | ||
Range on Protein: 157-336
Range on HMM: 95-248/265.0
TLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKygytdid
. . .. .|. |||... ...|||| .| .|||.. . .. || | |.||| |. ..| .| . . .| |||.| |
aereklksGstavvvliekdqlyvaWlGDsqallvrkg....eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk.......
llsaaksKPIIAEPEIHgAQPLDGVTGFLVLMSEGLYKALEaahgpgqaNQEIAAMIDTEFAKQT-SLDAVAQAVVDRVKR
. ...|... .||| . .|.| ..||. .. ..|. ... .|... .|. ||. .|. |
.......pyvsgeadva.eveldgseeylilacDGlwDvvn........eeevvklveefladgaedlsevakllveaake
|
|||||||||
| subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 157-229 | 7.9e-06 | 18.6 | In-house | 78-149 (292) | alignment | ||
Range on Protein: 157-229
Range on HMM: 78-149/292.0
TLEREISGGAMAVVAVLLNN-KLYVANVGTNRALLCK-STVDGLQVTQLNVDHTTENEDELFRLSQLGldaGKIK
|.. |... .| |. .. .|..|||| |||| . .. | || |. || |. . | |...
tidaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraG...Grve
|
|||||||||
| subfamily_PPM1K_pd | Subfamily PPM1K | 159-296 | 5.4e-08 | 25.3 | In-house | 93-216 (263) | alignment | ||
Range on Protein: 159-296
Range on HMM: 93-216/263.0
EREISGGAMAVVAVLLN-NKLYVANVGTNRALLCKSTvdglQVTQLNVDHTTENEDELFRLSQLG--LDAGKIKQVGIICGQESTRRIGDykvkygytdI
. . | |. | |..| . ..| .|..| ||.||. . ..| ||. | |.| |. . | .. . . . || .|| .
aellssGttatvsllrdGtelvlaslGdsrailcrnG....kakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGd.........l
DLlsaaKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKAL
|| |. .||.|| . . . ||||...|. .
dl....kryGviatPetkslkvdhaadsflvlitdgisfvv
|
|||||||||
| subfamily_PPM1G_pd | Subfamily PPM1G | 163-298 | 3.4e-13 | 42.4 | In-house | 295-418 (473) | alignment | ||
Range on Protein: 163-298
Range on HMM: 295-418/473.0
SGGAMAVVAVLLNNKLYVANVGTNRALLCKStvdGlQVTQLNVDHTTENEDELFRLSQLGldaGKIKQVGI-ICGQESTRRIGDYKVKYGYTdidlLsAA
. |. ||||.| ..||.|||.| |. |... | . .| .|| |.| || |. . | ||... | | | .||. | . | .
dsGttAvvaLlkekklivAnaGDsRcvlsrn...G.kAldlslDHkPeDevEleRiekAG...GkvdedgRvnGGLnlsRAlGDhaYkknee....L.pl
KSKPIIAEPEIHGAQpLDGVTGFLVLMSEGLYKALEA
| . | | |.|. .. | |||| ..|.. ..|.
keqmisAlPDikvlt.lteedeFlvlAcDGiWnvmes
|
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| subfamily_ILKAP_pd | Subfamily ILKAP | 164-300 | 6e-12 | 38.3 | In-house | 113-234 (293) | alignment | ||
Range on Protein: 164-300
Range on HMM: 113-234/293.0
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGL--QVTQLNVDHTTENEDELFRLSQLGldaGKIKQVGIICGQESTRRIGDYKVkygytdidllsaa
|. |.| . |.| |||||.| .|.|.. .| .. .| .|||. ...| |. . | |.... . | .| ||| .
dGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGdgrf.............
KSKPIIAEPEIHGAQpLDGVTGFLVLMSEGLYKALEAAH
|. .|. |... . |. |.|| .||.|...| .
krlGvistPdvkkce.LtendlfvvlaCdGLwkvfsade
|
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| subfamily_PPM1D_pd | Subfamily PPM1D | 164-224 | 1.3e-06 | 20.7 | In-house | 108-170 (309) | alignment | ||
Range on Protein: 164-224
Range on HMM: 108-170/309.0
GGAMAVVAVLLNNKLYVANVGTNRALLCKSTV--DGLQVTQLNVDHTTENEDELFRLSQLGLD
|. | | .. ..|||||.|| ...| .. . |. ..| .|| |. .| |. .|| .
aGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGe
|
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| subfamily_PP2D1_pd | Subfamily PP2D1 | 174-298 | 7.6e-10 | 31.1 | In-house | 186-295 (492) | alignment | ||
Range on Protein: 174-298
Range on HMM: 186-295/492.0
LNNKLYVANVGTNRALLCKStvdGlQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQ-ESTRRIGDYkvkyGytDIDLlsaakSKPIIAEPEI
||.||.| .|.||. | . .| .||..|. | |... | | ...| . |. . || .| | | | .| | .| ||..
elgvlyianaGnvqAvLcre...G.kaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny....G..dpkL.....kksvipePkt
HGAqPLDGVTGFLVLMSEGLYKALEA
. .|| . |||| | ||.. |..
tsv.kldeaaqflvlAsnGlWevlse
|
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| PPM_PTC7_motif | 286-333 | 4.5e-06 | 20.1 | In-house | 1-50 (51) | alignment | |||
Range on Protein: 286-333
Range on HMM: 1-50/51.0
VLMSEGLYKALEAAHGPGQANQEIAAM--IDTEFAKQTSLDAVAQAVVDR
.|.| ||. |. . .......... .|.|... .|.|....|.
iLAsDGLWDvlsdqeavdlvrdqlskkglspqeaAeklvdealargseDn
|
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