Gene PPP1C-3 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP1C
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP097_AA protein Get Run
MbreP097_AA_10-307 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 6-302 5.6e-125 409.5 In-house 1-298 (299) alignment 
Range on Protein: 6-302
Range on HMM: 1-298/299.0
LDVAGIIDRLLEVRGCRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICL
|||  .. .||.|       | |..|.|.  ||  |...|. .. || ..||...|||.|||| |.||.|...|||| . .||||||||||.| ||.|.|
ldvdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitl

LLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRY-SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLL
||..|. ||.....||||||| .|||.||||.||..|| | .||  | |.|. .|.. ... .|.| |||||| ||.|||. ...|| | |.  |  |||
llcfkikyperffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidll

WSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKKS
|.||.. | .|  | ||||. || |.|.. . . |.||..||||||.|||||||...|||.|||| |||.|||. ||| || ||.|.|..|||..|. 
wadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpksl
subfamily_PPZ_pd Subfamily PPZ 7-300 1.3e-131 431.6 In-house 2-296 (300) alignment 
Range on Protein: 7-300
Range on HMM: 2-296/300.0
DVAGIIDRLLEVR-GCRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICL
|.  ||..||.    ..  | | |.. ||  .|  ||| |||.| || |  .||| ||||||| |.|||| . ||||.. |||||||||||||||||| |
dideiiqklldagyaakrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletill

LLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLW
||.||. ||....||||||||| . |.||||||||||  ||.|||| | || ||.||.|| |||| |||||| |...|.|  | ||||||| ||. ||||
llcykikypenffllrgnhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllw

SDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADK
|||    ..| .|.||||. .    ..||| .  .||.|||| ||||||||| .| |||||||||||||||| ||.|.|   |.|||..| | | 
sdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldplds
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 10-301 3.6e-132 432.9 In-house 5-297 (298) alignment 
Range on Protein: 10-301
Range on HMM: 5-297/298.0
GIIDRLLEVRGCRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAY
 .. ..|.|       | ...|.... |.  |.. | . ..|. ..||.|.|||.|||| |.||||...|||| . |||||||||||.|.||.|.|||||
ellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllay

KVLYPDKIWLLRGNHECASINRIYGFYDECKRRY-SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDP
|| ||....||||||||..|||.||||.|||||| |..|...| | || ||..|.....|.| |||||. |..|||. ...||.| ... |  ||||.||
kvkypnnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadp

EREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKK
|. |..|||| ||||..||.| |...| . |.||..|||||| |||||||...|||.||||.|||.|||. |.|.||..|..||..|||..|.
enavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpekke
0049330 Metallo-dependent phosphatases 11-303 7.2e-114 372.9 In-house 12-304 (309) alignment 
Range on Protein: 11-303
Range on HMM: 12-304/309.0
IIDRLLEVRGCRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYK
.| .||..   .. |.. |.|.|.  |.| |.| .. ||.||.|.... ..||.|||..| |||.|. ||||.  ..||||.|||| .|||...||||.|
lilslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalk

VLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPER
.||||...|||||||.. .|..|||.||..|.|...||. |.|....||.|||. .||.|.||||||||..|||| ...||...|..||||||||||| .
llypdnvfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplp

EVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKKSK
..|..|.|.||....||...||.|| ...||||.|.|..|..||..|....|.||||||||||...|.||....| .|..||....|.. . .
iregfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpllll
subfamily_PPP1C_pd Subfamily PPP1C 21-300 1.7e-156 512.6 In-house 2-281 (282) alignment 
Range on Protein: 21-300
Range on HMM: 2-281/282.0
CRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLL
...||.|.|.|.||. |. .|||..|..|.||.|.|||||.||.||||.|.|||||.||.||.|.||||||||||||||||||.||||||. ||....||
skkgkevklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfll

RGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDR
|||||.|||||||||||||||||||||||||||.|||||.||.|..||.|.||||||.|. |.||...|||..||..|||||||||||..||..|.||||
rGnhesasinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendr

GVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADK
|||||||.|.||||| ..|||||.||||||||||||||.|||||||||||||||||||||...||..|..||||||||.|
GvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpakk
0053225 Metallo-dependent phosphatases 21-297 1.1e-103 339.6 In-house 14-290 (293) alignment 
Range on Protein: 21-297
Range on HMM: 14-290/293.0
CRPGKTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLL
 .  ... | | |.  |.| |.| .. ||.||.|.... ..||.||...| |.|.|. ||||.. ..||||.|||| .|||...||||.|.||||...||
elllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvll

RGNHECASINRIYGFYDECKRRY-SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPErEVENWAEND
|||||.. .| .|||.||..|.| . .||. ..|....||.||.. .||...||||||||  |||| ...||...|..|||.|||||||  ....|. . 
rGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.lwsgwlpsy

RGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKP
||....||...|..|| ...||||.|.|||| |||... ...||||||||||.|...|.||....| .|...|....|
rglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfap
0045823 Metallo-dependent phosphatases 25-307 3.8e-116 381.4 In-house 39-333 (473) alignment 
Range on Protein: 25-307
Range on HMM: 39-333/473.0
KTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNH
|   |.|...  |.  |.| .  ||.||.|.... ..||.|||..| |||.|. ||||.  ..||||.|||| .|||...||||.|..||....||||||
kegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNH

ECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPeREVEN--------WA
|.. .| .|||.||. ..|...|.. | .....||.|||. .||...||||||||..|||| ...|| ..|| |||.|||||||  |..         . 
ElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.weddgdgllrlrffg

ENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQ------LVTVFSAPNYCGEFDNAGAIMTVDANLmCSFQILKPADKKSKYRYA
 . ||....||.|.||.|| ...||||.|.|..|..|||..  ..      ..||||||||||...| .|....| .| .||....|.. . .. ..
nsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphplilplf
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 25-298 8e-101 330.2 In-house 20-295 (297) alignment 
Range on Protein: 25-298
Range on HMM: 20-295/297.0
KTVSLEEREISGLCLsAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNH
  |  ||| .  | | | . | |.  .. ..||.|.|||.|||. |.|||| . |.||.. |||||||||||. |.||| ||||||| .| ...||||||
skviteervlklldl.aldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnh

ECASINRIYGFYDECKRRY-SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSP---DLQALDQITNVQRPTDVpDTGLLCDLLWSDPEREVENWAENDR
||  .|..||||.||..|| |.... .| | || ||.. ..|.||.| ||||||   .  .|| . ...|.|.    .|..||||.||   .  . ||.|
ecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqr

GVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
|    || | | |   . .|||.|||||||.||||||| |.|||.|||| |||.|||. |.|..| .| |||.||.|.
gagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpt
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 25-298 2e-83 272.8 In-house 12-289 (290) alignment 
Range on Protein: 25-298
Range on HMM: 12-289/290.0
KTVSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNH
 . ......|  .   ..| .   | ||...||. | ||.|||  ..|| |.. |.||   .|||||||||| .|||   ||. ||..|. |. ||||||
vldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnh

ECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTD--VPDTGLLCDLLWSDPERE-VENWAEN-DR
|.  .||.|||..|  |. . .||| . | |. |.. | |. ||.| |||.|..... . .. ...|      | ||  ||||.||.|.  .  | |  |
evrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqr

GVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
..|  || . ....| .  |.|| |||.| |.|..|  ...|||||||| |.|.  | |||.||   |  |. .||| 
aisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkpr
subfamily_PPP2C_pd Subfamily PPP2C 27-301 1.2e-98 322.9 In-house 15-289 (290) alignment 
Range on Protein: 27-301
Range on HMM: 15-289/290.0
VSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHEC
 .||| |.  ||  |.| .  |  .  ...|| .|||||||..|.| ||   |  | . |||||||||||  |.||..|| | || |...| .|||||| 
kqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhes

ASINRIYGFYDECKRRYS-IKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPErEVENWAENDRGVSFT
  | ..||||||| |.|.  ..|| ||| |..||..|.| ..||| |||||| ...||.| ...|  .||. | |||||||||. . . |.  .||  .|
rqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgisprgagyt

FGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKK
|| || |||  . .| || ||||.| .||..  .|..||.|||||||    | .||. .| .|  ||   .|| ..
fgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 27-301 3.4e-95 311.3 In-house 8-285 (287) alignment 
Range on Protein: 27-301
Range on HMM: 8-285/287.0
VSLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHEC
 ......|  .   ..| .   | ||...||..|.||.|||. |.||.|.  | .|   ||||||||||| .||| . ||...|..|| |. |||||||.
dafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhev

ASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDT--GLLCDLLWSDPEREVENWAEND-RGVS
  ||..|||..| ||... .|.|.| | |. ||. | |. .|.| |||.||.|..||... ...||   .   ||  ||||.|||.. .  . |  |..|
kkinklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkirais

FTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKK
  ||   |...| . |.||| |||.|.|.||.|.....|||||||| |.||  | ||...|.  |  ||  ||| | .
vvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedfe
subfamily_PPP4C_pd Subfamily PPP4C 28-298 1.3e-103 339.2 In-house 15-285 (288) alignment 
Range on Protein: 28-298
Range on HMM: 15-285/288.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECA
 ..|.|.  || .||| .. |  . |...|| .|||.|||.||.|.||. .|  |  .||||||.||||. |.||. ||||.|| |||.| |.|||||. 
likeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr

SINRIYGFYDECKRRY-SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPErEVENWAENDRGVSFTF
.| ..||||||| |.| |...|.  |. |. |..||.. .|||| ||||||... ||.|  ..| ..||. | |||||||||| ..| ||   ||  . |
qitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe.daegwavsprgagylf

GADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
|.|.||.|  . |..|||||||.| .|| .  .....||.||||||    |  ||. .|..|   |.|.. |
gsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa
subfamily_PPP6C_pd Subfamily PPP6C 28-296 2.1e-94 308.9 In-house 14-282 (290) alignment 
Range on Protein: 28-296
Range on HMM: 14-282/290.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECA
 | | ..  ||    . .| |  .  ...|| .|||.|||.||.. || ..|  | .||.||||.||||  ||||. .||. |. |||.| |||||||. 
ylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesr

SINRIYGFYDECKRRYS-IKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPErEVENWAENDRGVSFTF
 | ..|||||||...|   . || .|. |. |..||.. ....| |||||||...||||. ..| ...|  | .|||.||||| .||.||  .||  . |
qitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpe.dvetwavsprgagylf

GADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILK
|. ....|.   .|.|||||||.||.|.... . .||||.||||||    |  .|.... .   .....|
gskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfk
subfamily_PPP3C_pd Subfamily PPP3C 28-289 1.2e-87 287.6 In-house 40-314 (452) alignment 
Range on Protein: 28-289
Range on HMM: 40-314/452.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECA
 |||...  .  .| . .  |. ||...||. ..||.|||.||.|.||| .| |  ..|||||||||||  |.|..  |.| |. ||....|||||||| 
rleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecr

SINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWA------E-NDR
 .   . | .||| .|| .........|..||.||.. .. .|.||||||... ||.| ...|  ..| .|.|||||||||  . .. .      . . |
hlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvr

GVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQ------RQLVTVFSAPNYCGEFDNAGAIMTVDANLM
| |. ..   | .|| . ||  | |||.. ..||. . .        |.|.||||||.. ..| .|.. .. | |
GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennvm
subfamily_PPG1_pd Subfamily PPG1 28-298 2.2e-83 273.0 In-house 13-296 (300) alignment 
Range on Protein: 28-298
Range on HMM: 13-296/300.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECA
 | |  .  |.   .| .. |  . ....|| . ||||||.|||| .|.  |  | . |||||||||||  |.||| ||.. |. || .| |||||||  
llpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesr

SINRIYGFYDECKRRY--SIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPE-----------REVEN
 | ..|||| || |.|    ..|| .|. |. | .||.. ..|.| ||||||. ...|||  ..|  .||. | |.||||||||           || ..
qitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqh

WAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
. . .||  ...| |.||||| . |.. | ||||.. .||. . . .| ||.||||||    |  .|. .  ..   |.. . |
fvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeea
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 28-297 8.2e-71 231.6 In-house 5-299 (302) alignment 
Range on Protein: 28-297
Range on HMM: 5-299/302.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHS------------GFpPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPD
.... |.  |. .  |..  |  | .. .|| | ||.|||. |..|.. .             .|   . ..|||||||||..|.| |||..|.||||| 
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysf.ssdkfvflGdyvdrGsksieciclvfalkvlypt

KIWLLRGNHECASINRIYGFYDECKRRYS----IKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRP-TDVPDTGLLCDLLWSDPE-
.  |||||||. .||  ||| .| . |..     ..|. | ..|  .|.||.| .||.| |||.|| |..|..|....|| ..| .  |  |||..||  
nyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpld

-------REVENWAEN-DRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKP
       .|  ..|.|  ||.|..|    |...  . .|.|| ||||..  |. |||...|.|.||||.|  | || ||.. ||.|   | ..|..
vqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 28-297 1.8e-70 230.5 In-house 6-300 (302) alignment 
Range on Protein: 28-297
Range on HMM: 6-300/302.0
SLEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHS------------GFpPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPD
.... |.  |. .  |..  |  | .. .|| | ||.|||. |..|.. .             .|   . ..|||||||||..|.| |||..|.||||| 
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysf.ssdkfvflGdyvdrGsksieciclvfalkvlypt

KIWLLRGNHECASINRIYGFYDECKRRYS----IKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRP-TDVPDTGLLCDLLWSDPE-
.  |||||||. .||  ||| .| . |..     ..|. | ..|  .|.||.| .||.| |||.|| |..|..|....|| ..| .  |  |||..||  
nyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpld

-------REVENWAEN-DRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKP
       .|  ..|.|  ||.|..|    |...  . .|.|| ||||..  |. |||...|.|.||||.|  | || ||.. ||.|   | ..|..
vqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 29-299 2.5e-116 380.7 In-house 6-276 (280) alignment 
Range on Protein: 29-299
Range on HMM: 6-276/280.0
LEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECAS
..| .| ..    .. ..|.  .. ..|||..|||.|||| |.||||.. .||| . |||||||||||.| || |.||||||| ||... .||||||..|
ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevis

INRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGA
||| |||.||.||||| .|.. | . .. ||..|.|. .|.| |||||..|..||......|| | .|  |  ||||.||| .|  |||| ||||  |||
inrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifga

DIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPAD
..| ..  . |.|||.| ||||.|||||||...||||||||.|.|||||. |.. ||..|. ||..|||| 
nvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpal
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 29-297 4.6e-115 376.9 In-house 8-282 (284) alignment 
Range on Protein: 29-297
Range on HMM: 8-282/284.0
LEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFP------PASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRG
|.|.|.  ||. |||.|  |.. | ..|||||.||.|||. |.| |..  |.|        . |||||||||||  |.| | ||.|||.|.|||. ||||
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrg

NHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGV
|||   .|. |||| |||.||| .|...|  .||..|..|||..||.| |||.| ||  |.|. ...||.|.|| |...|| |.||| ||| ..| .|| 
nhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprga

SFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKP
  .|||. |..|| ...|||. |||||| |||||||.|.|||.|||| |||..||..|...|| .|..||..|||
gkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp
PPP_3 29-296 1.6e-111 364.7 In-house 2-270 (271) alignment 
Range on Protein: 29-296
Range on HMM: 2-270/271.0
LEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECAS
|.|.|.  |. ...| .  |..|....|||..|||.|||..|.|.||...|..| ..||||||||||||.|||...||||.|..||....|||||||...
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

INRIYGFYDECK-RRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFG
||..|||..|.. .... |..|.....|..||.||.. .|....||||||... ||||.. .|...||..|.|.|||.|..... | .....||....||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg

ADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILK
.|..|.|| ...|.||.|||...|.|||.......||||||||||....|||||......|...|..|.
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 29-299 2.4e-98 321.8 In-house 8-278 (281) alignment 
Range on Protein: 29-299
Range on HMM: 8-278/281.0
LEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECAS
. ..||  .   ..  |  |  |  ...|... ||.|.|. |. ||||  | .|   ..|||||||||.||||.. ||...|. |.|.|.||||||| ||
ytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheias

INRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGA
.|.||||| ||. .| ..||  |  ||| ||..| .| .. | ||||||.| |||.. |  .| . .| ||. ||||.||. .||.| .  ||.||||| 
vnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGk

DIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPAD
..|..   . ...|| |||||| |||| .. |.|.||||.||||  . ||.|...||..|  |.. | || 
nvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpas
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 29-83 1.9e-16 53.1 In-house 9-63 (317) alignment 
Range on Protein: 29-83
Range on HMM: 9-63/317.0
LEEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPA
..|.|.  ||. |||.|  ||. |.|.|||.|.||.|||. |.| |..  |.| .
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls
PPP_1 30-283 8.2e-109 355.9 In-house 2-263 (264) alignment 
Range on Protein: 30-283
Range on HMM: 2-263/264.0
EEREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASI
||.|.  |. ...| .  |..||........|||.|||..|.|.||. .|..| ..||||||||||||.|.|...||||.|. ||....|||||||....
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv

NRIYGFYDECK-RRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLL-------WSDPEREVENWAENDRG
...|||..|.. ..|| ...||.||.|..||.||.. .||...||||||.|..|||| ...| |.||..| |||||       .||.... | .|...||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG

VSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMT
....||.|..|||| ...|.||.|||.|.|.||||...|..||.|||.||. |..|.||...
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
PP2Ac_SM00156 31-298 4e-113 369.9 In-house 3-270 (271) alignment 
Range on Protein: 31-298
Range on HMM: 3-270/271.0
EREISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASIN
. |.  |. ...| . .|..|....||| ..||.|||..|.|||.|  |.|| . |.|||||||||.||.|.|.||.|.|.|||.|. |||||||. |.|
keevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvn

RIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGADI
.||||..|.||.|. .... |...|..||.||.| .||.| ||||||.|. ||.|....|. . |. |||.||||||||....... . ||.|..||.|.
kiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFgeda

VEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
|..|| ...|.||.|||.||..||||||...|||.|||||||.||.|..|...|. ||..|.. ||..
vkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 32-294 6e-74 242.0 In-house 23-288 (307) alignment 
Range on Protein: 32-294
Range on HMM: 23-288/307.0
REISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINR
 |.  .   |.  | .|  |. .. |. . ||.|||. |.. .|   | || . |.| |||||||  |||.| ||..||. ||..| ||||||| | .|.
eefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnk

IYGFYDECKR---RYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGA
 ||||.||     .   ..|  |  ||| ||..|..| ||.| |||||| | .||.. |  .|   |  |.. |.||.||.  | .|    ||  ||||.
kygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgt

DIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQI
....    .  ..|| ||||.. |||  .. |.|.|.|||| ||  . |||... ||  |      
nviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlva
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 33-305 4.2e-105 344.2 In-house 7-281 (284) alignment 
Range on Protein: 33-305
Range on HMM: 7-281/284.0
EISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRI
..  | . | . |  .|||.  ..|..||||.|||. |.||||.. |||  . ||||||||||||. |||| ||.||||..|.....|||||||. ||.|
dvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinki

YGFYDECKRRYSI-KLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTG-LLCDLLWSDPEREVENWAENDRGVSFTFGADI
||||.||.|||    ....|   |  .|..|.| ..|.| |||.|  || . |.  ..|| | |.   |  |.|||||    . |  | ||||. ||.| 
ygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsda

VEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADKKSKYR
. |.| . ..||. ||||||.|||||||.|.|||.|||| |||.|||| |.| |. ||.||| .|.|  | .. |
lrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkkiarrr
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 33-84 6.4e-11 34.9 In-house 15-66 (339) alignment 
Range on Protein: 33-84
Range on HMM: 15-66/339.0
EISGLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPAS
|.. ||  |||   .||..|.|.||. . ||.|||. |.| ...  |.| .|
elaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwplss
subfamily_PPPLV_pd Subfamily PPPLV 36-288 3.7e-59 193.4 In-house 4-279 (290) alignment 
Range on Protein: 36-288
Range on HMM: 4-279/290.0
GLCLSAREAFLAEPMLLRLQAPVKICGDVHGQYYDVLrLFEHS----G-FPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASIN
 ||  | . ..||  || |..|. . ||.||.| |.   ||.     |     .|.||||||||||. |.| |. ||| ||||| |..|||||||  |. 
slcdvavdilaaeerllelksptyvlgdlhgnyrdli.yfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq

RIYGFYDECKRRYSIKL---WKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQR-----PTDVPDTGLLCDLLWSDPEREV----------
  . .. |.. ..  .|   |..|...|. ||.|||. .|.||.|.|.    ..  .|. .|      . |.  . |  |.|||||. .           
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl

-ENWAEND-RGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAgAIMTVDANL
 | ...|| || .  |..| .|.|| . .|. . |||.| | |...  . .|.||||. .|||  ..| |.. || . 
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssnea.alilvdkkk
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 41-298 8.1e-90 294.1 In-house 18-275 (280) alignment 
Range on Protein: 41-298
Range on HMM: 18-275/280.0
AREAFLAEPMLLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECK
    |. |  |   .||.|. ||.| || |. |||.  |  |    .||||||||| | .| . ||.. |. | |.|.|||||||  |.|.||||| ||.
veaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecq

RRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDL
 .| . ||  |  ||| .|...... ...| ||||||.|  || | |. || .  | ||| |||||||  . | |  . ||.|. ||  .||.     ..
ykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqackslei

DLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPA
||| ||||||.||||..| |.|.|||| |||| .| || |.. ..|||  ||| | | 
dliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlipp
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 51-300 6.2e-74 242.0 In-house 2-258 (263) alignment 
Range on Protein: 51-300
Range on HMM: 2-258/263.0
LLRLQAPVKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSI-----
|| ||||..|||| |||| |.||.|.  |    . ||||||||||| .||| | ||.. |.  | |. |||||||  .||. |||. | |.|.       
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

KLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDT-GLLCDLLWSDPEREVENWAEND-RGVSFTFGADIVEKFLLQHDLDLI
 ... | . |. .|..|.|. .|.| |||.|| |..||.|  .  | .   |  | |||||.|||.. . .  |  | .|  ||   |. .  . |.|||
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidli

CRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSFQILKPADK
 ||||||| || |||.|.|.|||||  |  |. |  |.. |.  |  ||  ||| | 
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedf
subfamily_PPP7C_pd Subfamily PPP7C 56-190 1.7e-37 122.1 In-house 64-201 (383) alignment 
Range on Protein: 56-190
Range on HMM: 64-201/383.0
APVKICGDVHGQYYDVLRLFEHSGFPPA-SSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRY---SIKLWKTF
  | .|||.||.  |.| ..   |.| .  .|.| ||.|||||.|.| ...|||. ..|| ...| |||||   .|  |||  | . .|   . |. ...
kevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrll

TDCFNCLPVAAVVADKIFCCHGGLSpDLQALDQITNVQR
 | |  ||.|... .||. .|||.| |   |. . ...|
edvfawlplatlidekilivhGGis.dktdlelldkier
subfamily_PPP5C_pd Subfamily PPP5C 57-292 7.9e-83 271.1 In-house 66-303 (322) alignment 
Range on Protein: 57-292
Range on HMM: 66-303/322.0
PVKICGDVHGQYYDVLRLFEHSGFPP-ASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCF
 . .|||.|||.||.| .||  | |    .||| ||.||||  |.|.| .||..|.|||....| |||||  ..|..||| .|.| .|. |. . ||. |
kltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfegevkakytekvadlftevf

NCLPVAAVVADKIFCCHGGL-SPDLQALDQITNVQRPTDVPDTGLLCDLLWSDPEREVEnWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGY
| ||.| |. .|.. .|||| | |  .||.. ...| .. |. |||..||||||...    ..  |||...|| |. .||| . .|.|| |.|.| |.||
nwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanG.rspskrGvgvqfGpdvtkkflkennleliirshevkeeGy

EFFAQRQLVTVFSAPNYCGEFDNAGAIMTV-DANLMCSF
|.  . .|.||||||||| . .| ||..|. ...|   |
evehdGklitvfsapnycdqmgnkgafitlrgddlklkf
Metallophos Calcineurin-like phosphoesterase 57-249 1.1e-43 142.9 Pfam-A 2-198 (200) alignment 
Range on Protein: 57-249
Range on HMM: 2-198/200.0
PVKICGDVHGQYYDV----LRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLL--LAYKVLYPDKIWLLRGNHECASINRIYGFYDECK----------
.. ..||.||...|     |.|... . ...  .|||||.||||. |.||..||  |..|.|.|....|||||||. ..|  |||..|.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------RRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQItnvqrptdvpdtgllcdllwsdperevenwa
                         ..  . .  . ..|..|| .| |  ||...||.||....  |.|                               
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

endrgVSFTFGADIVEKFLLQHDLDLICRAHQV
      |. || | .||.|.....||..|.|. 
.....gselfgpdalekllekygvdlvlrGHtH
PPP_2 58-249 5.1e-80 260.8 In-house 1-197 (198) alignment 
Range on Protein: 58-249
Range on HMM: 1-197/198.0
VKICGDVHGQYYDVLRLFEHSGFPPASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECK-RRYSIKLWKTFTDCFN
|..|||.|||..|.|.||......| ..||||||||||||.|||...||||.|. ||....|||||||....|..|||..|.. .... |..|.....|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

CLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVPDTGLLCDLL----WSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQV
.||.||.. .|....|||||.... ||||.. .|....|..|.|.|||    .|||... | .|.. ||....||.|..|..| ...|.||.|||.|
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
PPP_4 58-249 5.9e-77 251.2 In-house 1-196 (197) alignment 
Range on Protein: 58-249
Range on HMM: 1-196/197.0
VKICGDVHGQYYDV-LRLFEHSGFPP-ASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCF
| ..||.|||..|. |.|.. .|.|.  .||.||||||||||.|||...||||.|. ||....|||||||..|.|..|||..|...... ...|...|.|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvf

NCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVP-DTGLLCDL-LWSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQV
..||.||....|....|||||..|. ||.| ...|....| . ....|| |||||... | .|.. ||....||.|..|||| ...|.||.|.|..
dllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
PPP_5_Dcr2 58-250 4.7e-73 238.4 In-house 1-199 (199) alignment 
Range on Protein: 58-250
Range on HMM: 1-199/199.0
VKICGDVHGQYYDV-LRLFEHSGFPP-ASSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRR-YSIKLWKTFTDC
| .|||.|||..|. |.||.. |.|.   .|.||||||||||.|||...||||.|..||....|||||||. ..|.||||..|.... .. |..|...|.
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FNCLPVAAVVADKIFCCHGGLSPDLQALDQITNVQRPTDVP-DTGLLCDL-LWSDPEREVEN-WAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVV
|..||.||....|....||||||... .... ...|....| ..|  .|| |||||....|. .... ||....|| |..|||| ...|.||.|.|...
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk
subfamily_YNL217W_pd Subfamily YNL217W 60-177 1.3e-07 24.4 In-house 14-138 (235) alignment 
Range on Protein: 60-177
Range on HMM: 14-138/235.0
ICGDVHGQYYDVLRLFE--HSGFPPASSYLFLGDYVDRGKQSLETICLLlaykvlYPDKIWLLRGNHECASINRIygfydECKRRYS-------------
. ||||| | ....|..    |  .    ...|| ...| .|.|.. ..        |.   ..|||| . . ..     .  ..               
vvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllay.....kwvkkpkgaeplefsskfsf

I--KLWKTFTDCFNCLPVA-AVVADKIFCCHGGLSP
.  || |  ..    |. .  . .|...  |.||.|
lesklskadmeyarelgfsldipsdellvvhaGlvp
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 84-298 6.9e-100 327.3 In-house 101-315 (317) alignment 
Range on Protein: 84-298
Range on HMM: 101-315/317.0
SSYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALD
. |||||||||||  |.| . ||.|.|.|||||..|||||||  ..|. |||| |.|.||| .|...|   ||.||..|||..||.| |||.| .|  |.
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMT
|. ...||.|.|| |.|.|| |.||. ||. ..|  || .. |||. |..|| ..||||. ||||||||||||||.|.|||.||||.|||..||..|...
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDANLMCSFQILKPA
|| .|..|...|.| 
vdkklkisinvlrpe
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 85-301 1.4e-74 244.3 In-house 121-337 (339) alignment 
Range on Protein: 85-301
Range on HMM: 121-337/339.0
SYLFLGDYVDRGKQSLETICLLLAYKVLYPDKIWLLRGNHECASINRIYGFYDECKRRYSIKLWKTFTDCFNCLPVAAVVADKIFCCHGGLSPDLQALDQ
 |||||||||||  |.| . || | |. |||.|.|||||||  |.|  |||| | . ||  .|.. | . || .|..||. . |.| |||.|  | ...|
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq

ITNVQRPTDVPDTGLLCDLLWSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTV
.. ..|| ..|| |.| || |.||.   . .    || || ||   .  || . ||... | |||||||||||  |.|||.||||||||. ||. |....
fsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsi

DANLMCSFQILKPADKK
| .|  | ....|  . 
dkklkisinvfrpesrd
subfamily_PPP7C_pd Subfamily PPP7C 200-292 3.2e-21 68.5 In-house 237-329 (383) alignment 
Range on Protein: 200-292
Range on HMM: 237-329/383.0
LCDLLWSDPEREVENWAENDRGVSFTFGADIVEKFLLQHDLDLICRAHQVVEDGYEFFAQRQLVTVFSAPNYCGEFDNAGAIMTVDANLMCSF
. |.|||||. .   ...  ||    ||.|. .|.| ...|.|. |.|.   .||||  .....|.||| ||  |  | || . .  .|.  .
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltpri