Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0045823 | Metallo-dependent phosphatases | 4-294 | 8.4e-115 | 377.0 | In-house | 27-329 (473) | alignment | ||
Range on Protein: 4-294
Range on HMM: 27-329/473.0
TSDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVR
.|||. ||... ...| | ... |...|||||..|.|. |.| ...|.||.|||..|||.|... | | ....|.||.||||..|.| . || |||..
lldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkik
YPERISILRGNHESRQITQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR
||... .||||||.|.....|||.||.|.|| . .. .| .... |||. ... .|.. ||||||. ..|| || ..|..|.|..|...|||||||..
ypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed
AG--------WNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRN------VVTIFSAPNYCYRCGNQGGIMELDDTLnYSFLQYDPA
| . ||||||. ||. . ||| . |||..| |.|. |.||... .|.. ..|.|||||||.|.|| ......|..| .|| |.||.
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdps
PRPQG
| |.
phpli
|
|||||||||
0049330 | Metallo-dependent phosphatases | 4-293 | 3.1e-108 | 354.4 | In-house | 14-303 (309) | alignment | ||
Range on Protein: 4-293
Range on HMM: 14-303/309.0
TSDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVR
.|.||..||... .|.|.|....||..|||||| .|.|. |.| ...|.||.|||..|||.|... | .| ....|.||.||||..|.| ..|| |||..
lslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkll
YPERISILRGNHESRQITQVYGFYDECLRKYAsPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPD-D
||... .||||||.|.....|||.||.||||. . .| .|.|... |||. ... .|.| ||||||. ..|| ||...|..|.|..|..||||||||. .
ypdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpi
RAGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPRPQ
| |. .|||.|. || |. |.| ..|||. | |.|..|..|. . .|....|.|||||||.|.||.|...|.|..|..|||...|.|...
regfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplll
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 5-292 | 1.3e-177 | 582.1 | In-house | 2-289 (290) | alignment | ||
Range on Protein: 5-292
Range on HMM: 2-289/290.0
SDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRY
.|||..||.....|||.|...| ||||||||||.||||.||.|||||||||||||.||||||.|||..|.|||||.||||||||.|||.|||||||||||
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry
PERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDRA
.|||.|||||||||||||||||||||||||....||.|||||||.||||.||..|||||||||||...|||.||..||.||||||||.|||||||||||.
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrg
GWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPRP
||..||||||..|||..||.||.||||..|||||||||||.||||||||||||||||||||||||..|.||||.|.|||||.|||||
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 5-289 | 2.5e-142 | 466.3 | In-house | 1-285 (288) | alignment | ||
Range on Protein: 5-289
Range on HMM: 1-285/288.0
SDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRY
|||| |||..|. . . |...| ||.||.||| .||||..| .|||||||.|||||||||||..||.||.|||||.||.||||..|||. ||.||||||
sdldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvry
PERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDRA
|.||...||||||||||||||||||||||| | .|| | |..||.|.|. ... .|||.||||||. .||| || .|| ||||||||.||||||||.|
pdritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae
GWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPA
||.|||||||. ||. |.|.||..|.. .|.|||||||||... ...|.|..||||||||||| |.|||..|.. | .. |
gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa
|
|||||||||
0053225 | Metallo-dependent phosphatases | 5-290 | 4.5e-104 | 340.8 | In-house | 7-292 (293) | alignment | ||
Range on Protein: 5-290
Range on HMM: 7-292/293.0
SDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRY
..||..||... |.|.|....||...|||||..|.|. |.| ...|.||.||...|||.|... | .| ....|.||.||||..|.| ..|| |||..|
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly
PERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDRA
|... .||||||.......|||.||.|||| . ..| ...|... |||. |.. .|.. ||||||. ..|| ||...|....|.||...||||||||..
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws
GWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAP
|| |.||.|. || |. ..| ..|||. | |.||.|..|. . .|...||.||||||..|.||.|....||. |...| ...| .
gwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 5-184 | 4.5e-39 | 127.3 | In-house | 18-203 (383) | alignment | ||
Range on Protein: 5-184
Range on HMM: 18-203/383.0
SDLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSC----PVTVCGDVHGQFYDLLELF-RIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVA
..... ||... |.| . . |. .||..| | |. .|| ||||||.||.. ||| .. . | .. .|.| ||.|||| ||| . .|.|
deveklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillilla
LKVRYPERISILRGNHESRQITQVYGFYDECLRKY--ASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSpQATTLDAIRDMDRFQ
| . ||. . . ||||| . ||| | || . . . . |.| .|||. |....|. .|||.| . | |. . ..| .
lllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis.dktdlelldkiersk
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 6-282 | 6.1e-129 | 422.3 | In-house | 1-277 (290) | alignment | ||
Range on Protein: 6-282
Range on HMM: 1-277/290.0
DLDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYP
.|| ||.... | | |...| ||.. ...|..||||. ||.|||||||.|||||||.|||| ||.||.|.|.|.||.|||||.|.|..|.|..||..||
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp
ERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDRAG
.|| .|||||||||||||||||||||.|| . ..| |.|..||.|... ... |..|.||||||. .||| || ..| ||.||.|..|||.||||.|
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvet
WNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYS
|.|||||||. ||. |..||...| |..|.||||||.||... | ..||..||||||||||| |..|.|. . .
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeere
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 7-291 | 4.5e-123 | 403.3 | In-house | 1-298 (300) | alignment | ||
Range on Protein: 7-291
Range on HMM: 1-298/300.0
LDAQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPE
|| .|... . | | .| |..| ||.| .|||| |. .|||| |||||||||.||.|.|||.|| |||||.|||||||..|||...||..||.|||
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps
RISILRGNHESRQITQVYGFYDECLRKY-ASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPD----
||..||||||||||||||||| |||||| . || |.|..||.| |. ... .|.|.||||||.. ..| |. .|||.|||.|| ..|||||||.
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn
------DRAG--WNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPR
|| | . ||.||||. .|| | |.| |.| .. | |||||..||.. | . |..|||||||||||. |.|| . ... | |. ||.
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeape
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 9-290 | 2.4e-96 | 315.3 | In-house | 13-295 (298) | alignment | ||
Range on Protein: 9-290
Range on HMM: 13-295/298.0
AQIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERI
. ... . |...|.... |.|.||.|... . . || |..||||.|||. ||| || .| |..||||.||||||| ...| ..||.| ||.||...
vslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnf
SILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDD-RAGWN
.|||||| .| .|||||.|| |.|.| .... | |.|. ||||.|. .|.|.|||||.. ..|| .|.. | .. ..| ||||.||.. ||.
fllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwa
VSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAP
. ||... ||. | ... . . ...||||.| .|... ....|||||||.|| . | ..|..|. | || . |.
ensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpek
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 10-292 | 3.6e-86 | 282.1 | In-house | 24-312 (322) | alignment | ||
Range on Protein: 10-292
Range on HMM: 24-312/322.0
QIEQIRSGKQLDEQQIKLLCEKAKEILSQESNVREVSCP----VTVCGDVHGQFYDLLELFRIGGEVPHT-NYLFMGDYVDRGYFSVEAVTLLVALKVRY
.|.... |.| .. . . .|||.|.... . |.. . .|||||.||||||||..|.. | . .. ||| ||.|||| |||| . .|...|. |
llelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfklly
PERISILRGNHESRQITQVYGFYDECLRKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLS-PQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR
|... . |||||| .. ..||| .|. ||.. .| ||..|..|||. ... ... .|||| . ||| .| .||... |.|| ...||||||...
PnhfflsrGnhesdnmnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqea
AGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMEL-DDTLNYSFLQYDPAPRP
.| . | || |..|| |...| ..|.|. | |.|.. .||.. .|| ...|.||||||| . ||.|....| .| |. | ... . |
nGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeavehp
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 15-291 | 1.1e-88 | 290.3 | In-house | 19-296 (299) | alignment | ||
Range on Protein: 15-291
Range on HMM: 19-296/299.0
RSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGN
| | ..||... ||. ||... ... . || |. ||||.|||. ||| .| . | |..|.||.||||||| .| .|||.. |..||||. .||||
rltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgn
HESRQITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGA
|| | .|||||.|| ..|.| .|. | | |...|||||. .|.|.||||||. .||| .||. | |. | ||||.|||. .| ||
hecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgv
GFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPR
. ||. | .. . .. ..|||||.| .|... ....||||||| || . | ||..|. | .| . |.|.
syvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpk
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 15-291 | 7.3e-87 | 285.0 | In-house | 36-324 (452) | alignment | ||
Range on Protein: 15-291
Range on HMM: 36-324/452.0
RSGKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGN
.|.|... . |.| ..|..|... ||. |.||.||.||||||||.|| .||. .|.|||.||||||||||.|.| | |||. ||... .||||
lkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGn
HESRQITQVYGFYDECLRKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDRAGWNV------
||.| .|. . | .|| || .|. ... || |||. |...| .|.||||||. ..|| |...|||.|.|. ||.|||||||| .. | .
hecrhlteyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfv
--SPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHD------RNVVTIFSAPNYCYRCGNQGGIMELDDTlNYSFLQYDPAPR
|.|| . .. . . || ..| | | |||. .|.. .. ..|.||||||. |.. ...... . |.. .|
pnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn.vmnirqfnssph
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 17-70 | 3.4e-12 | 39.1 | In-house | 6-59 (317) | alignment | ||
Range on Protein: 17-70
Range on HMM: 6-59/317.0
GKQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGG
. ..|... || .|.|.. .| .|. .|||..||.|||| ||| |. . |
qdlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 18-284 | 5.8e-104 | 340.2 | In-house | 8-274 (282) | alignment | ||
Range on Protein: 18-284
Range on HMM: 8-274/282.0
KQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHES
.| |..|. |..||.||| ... . |.. ||...||.|||..||| || ..| |..||||.||||||| .|.|...||.|.|..|||.. .|||||||
vklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhes
RQITQVYGFYDECLRKYASPaVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDD-RAGWNVSPRGAGFN
.|...||||||| |.| . .| ||| |..|||. ||. .|.|.||||||. . |. ||.. | |||..| .|||||||||. . ||. . || |.
asinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsft
FGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFL
|||.| |.| . | | .| ||||.| .|... .|..||.||||||| . .|.|.....|..| ||
fgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfq
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 18-285 | 6e-81 | 265.0 | In-house | 6-279 (284) | alignment | ||
Range on Protein: 18-285
Range on HMM: 6-279/284.0
KQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEV------PHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISIL
| |.|... || .|.|.. .|. .|. .||...||.|||| ||| |. . | ...|||.||||||| ||.| .||| |.|...|... .|
kllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfll
RGNHESRQITQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSP
||||||| . . |||| || ..| | |.. | | .||. .|...|.|.|||.| . |. . ...| ..| | ..|| |.||. . |.. ||
rgnhesrpvnmqygfyleckkry.sealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesp
RGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQ
|||| ||. .||... | .. ||||.||.|... ||..||||||| || . | . ....|. | ||
rgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftv
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 18-277 | 1.7e-56 | 184.6 | In-house | 4-288 (302) | alignment | ||
Range on Protein: 18-277
Range on HMM: 4-288/302.0
KQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGG--E---------VPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPE
|....... ||.|. | |..|... |.| |||. ||.|||| ||. .. | . ..|.|||||||. |.| ..|. |||| ||.
keysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt
RISILRGNHESRQITQVYGFYDECLRKYASP---AVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDR-FQEVPHEGPMCDLLWSDPDD
. .||||||.. | ||| .| ... .| | . | |.||. || ..|.|.|||.||. ..|. |....| ..|| .. |||..|| |
nyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpld
RAGWNVSP----------RGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDD
. . . || . | .. ... . .|..| |||| . |||.. |....||||||.| |.| ....|
vqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdt
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 18-277 | 2.3e-56 | 184.2 | In-house | 5-289 (302) | alignment | ||
Range on Protein: 18-277
Range on HMM: 5-289/302.0
KQLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGG--E---------VPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPE
|....... ||.|. | |..|... |.| |||. ||.|||| ||. .. | . ..|.|||||||. |.| ..|. |||| ||.
keysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt
RISILRGNHESRQITQVYGFYDECLRKYASP---AVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDR-FQEVPHEGPMCDLLWSDPDD
. .||||||.. | ||| .| ... .| | . | |.||. || ..|.|.|||.||. ..|. |....| ..|| .. |||..|| |
nyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpld
RAGWNVSP----------RGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDD
. . . || . | .. ... . .|..| |||| . |||.. |....||||||.| |.| ....|
vqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdt
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 19-285 | 2.5e-76 | 249.8 | In-house | 22-291 (297) | alignment | ||
Range on Protein: 19-285
Range on HMM: 22-291/297.0
QLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESR
. |... | . | ... .. .. || .|. ||||.|||| ||| ||. || | .||||.||||||| ||.|.. ||.| ||..| . .||||||
viteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhece
QITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSP---QATTLDAIRDMDRFQEVpHEGPMCDLLWSDPD-DRAGWNVSPRGAG
. .|||||.|| ..| | ... | |.|..||||||. .|.|.|||||| . |||..|...| .| .|. ..||||.|| .|. ||||
fvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrgag
FNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQ
||. . | ...||||.| .|... |..||||||| || . | .| |. |. ||
cgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfei
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 19-288 | 2.7e-73 | 239.4 | In-house | 9-281 (287) | alignment | ||
Range on Protein: 19-288
Range on HMM: 9-281/287.0
QLDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESR
.....| . ||..||| . . || |.|..||.|||. ||| .| | |...|||.||||||| |.| . || .||..||... .|||||| .
afsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevk
QITQVYGFYDECLRKYAsPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQE--VPHEGPMCDLLWSDPDDR-AGWNV-SPRGAG
.| ..|||..| ||. .. | |.|. ||| |...|.|.|||.||. .|| .. . . . .|| . ||||.||. . .. |.
kinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkirais
FNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
||| . ... .. .. .| |||... ||... |...||.|||| |. . | | .. ....|. || . |
vvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp
|
|||||||||
PPP_3 | 20-287 | 4.5e-112 | 366.5 | In-house | 2-270 (271) | alignment | |||
Range on Protein: 20-287
Range on HMM: 2-270/271.0
LDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQ
|.|...| |..|.||||..|||. |.| |||||||.|||..||||||..||..|.|.|||.|||||||..|.| ..||.|||..||... .|||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
ITQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDL-LWSDPDDRAGWNVSPRGAGFNFG
|..||||..|.|.|. . |.......|..|||. |........||||||. ..|| |. ..|..|||.||...|| |.|||... |.. |.||||. ||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg
KTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYD
. |.|||...| |..|.|||.|..||.. ||..|||.|||||||.|..|.| |..|...|...| |..
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 20-288 | 3.2e-78 | 256.3 | In-house | 25-293 (300) | alignment | ||
Range on Protein: 20-288
Range on HMM: 25-293/300.0
LDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQ
| ...| .| ||.|.. . .. |.| .| . ||||||. ||| || | | .||||.||||||| |.|.. ||.. |..||| . .|||||| .
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecan
ITQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGAGFNFG
.|.|||||||| |. .| | | |. |||. .| .|||.|||||| ..| || . | .|| | . ||||||| | |. || . .
vtrvygfydeckrrc.nikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycyn
KTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
| ..| |. ...||| .| .|... ||..||.||||||| | | .| . . | || ||
kvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldp
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 20-288 | 2.7e-66 | 216.5 | In-house | 16-288 (290) | alignment | ||
Range on Protein: 20-288
Range on HMM: 16-288/290.0
LDEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQ
. ...| . ||..||| . || |... ||.|||. .||. | | |. ..||.||||||| |.| || .|.||.... .|||||| |.
fsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrk
ITQVYGFYDECLRKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRF--QEVPHEGPMCDLLWSDPDD--RAGWNV-SPRGAG
. ..|||..| || .| .| . |.|. |.| |.|.|.|.|||.|.. . .... . . . .|| . ||||.||. .. |.
vnrlygfkeelarkrgs.rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqrais
FNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
||| . ... .. .| .| |||.. ||||. |...||.|||| |. . | | |... ..|. |. |
vvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkp
|
|||||||||
PPP_1 | 21-275 | 7.7e-110 | 359.3 | In-house | 2-264 (264) | alignment | |||
Range on Protein: 21-275
Range on HMM: 2-264/264.0
DEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQI
|.... |..|.||.|..|.|. ||| ..|||||.||||.|||.||..||..|.|||||.|||||||..||| ..||.|||..||... .|||||||||.
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv
TQVYGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDL--------LWSDPDDRAGWNVSPRG
|.||||..|.|.|. | .. ..||.||.|||. |.. .|...||||||. ..|| || ..|..|||.||..||| |..|.... ... |.||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG
AGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMEL
||. ||| |.|.|...|.|..|.|||....||... ..|.|||||||.||.....|.| ...|
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl
|
|||||||||
PP2Ac_SM00156 | 21-289 | 2.9e-106 | 347.4 | In-house | 2-270 (271) | alignment | |||
Range on Protein: 21-289
Range on HMM: 2-270/271.0
DEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQI
...... |.|..||||.||.|..||| ||||.||.|||..|||.|.. .||.|...|.|.|||||||..|.| ..||.|||..|||.. .|||||||...
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv
TQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDP-DDRAGWNVSPRGAGFNFGK
...|||..|. ||| . .. |...|. |||. ||...|.|.||||||. ..|| || ..|..| |.||...||||||| .. |.. | ||... ||.
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge
TVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPA
. .|| ..| |. | |||..|.||... .|...||||||||||....|.. .......|. |. |....
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 21-289 | 1.3e-82 | 270.1 | In-house | 7-275 (280) | alignment | ||
Range on Protein: 21-289
Range on HMM: 7-275/280.0
DEQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQI
| .|. . || |.||. .. . || .||.||||.|||. ||| || . | .||||.||||||| . .| . ||.| |||||... ||||||| .|
keadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisi
TQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPD-DRAGWNVSPRGAGFNFGK
. |||.||. |.| | |... | .|.| |||. || .|.|.|||||.. .|| .... | . ..| ||||.||. . .|| ..||. ||.
nrkygfkdevkrry.slalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifga
TVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPA
| .. . . .||| ||.| .|... |...||.||||.|. |. ... .|. | || ||
nvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 22-292 | 1.4e-81 | 266.8 | In-house | 10-280 (281) | alignment | ||
Range on Protein: 22-292
Range on HMM: 10-280/281.0
EQQIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQIT
...|. . ... |.|.|... |. |..| ||.|.|| || .|| . | ||.. ..|.||||||| |.|.. || .||.||..|| .|||||| ..
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvn
QVYGFYDECLRKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGAGFNFGKT
..|||| || || .|. | |. ||...|..... |.||||||. |.|| .|.. . . .. | . ||||.|||.. .| | ||..| |||
kiygfyvecvtkyGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGkn
VSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPRP
| .. .. .. .| ||||.|..|.. |...|.||.|||| | . .. .|.||. |.... ||. |
vvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpasep
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 24-288 | 9.5e-68 | 221.7 | In-house | 7-273 (284) | alignment | ||
Range on Protein: 24-288
Range on HMM: 7-273/284.0
QIKLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQV
... | .| .|. .. . || |. .|||.|||| ||| || | ..||||.||||||| .|.. ||.| || .|... .|||||| | ..
dvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinki
YGFYDECLRKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGP-MCDLLWSDPDD-RAGWNVSPRGAGFNFGKTV
||||.|| |.| |.|.. | .| .||| || ..|.|.|||.| . .| . | . | |.||||| . . ||| || . ||
ygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsda
SEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
.. . .. ||||.| .|... .| .||||||| || . | .| .. | ||. |
lrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrp
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 26-69 | 6.5e-07 | 21.7 | In-house | 17-60 (339) | alignment | ||
Range on Protein: 26-69
Range on HMM: 17-60/339.0
KLLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIG
|| .|.|.. | . .. .|. | ||.|||| ||| .. .
aelchrareliwsepiflkleapicvmgdihgqfddllamldmn
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 27-289 | 4.2e-67 | 219.5 | In-house | 27-292 (307) | alignment | ||
Range on Protein: 27-289
Range on HMM: 27-292/307.0
LLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGF
. .|. |.| | . .. |. | ||.|||| ||...| . | | | |.| ||||||| .|.|.. ||.. |. ||| | .|||||| .. . |||
nviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygf
YDECLRKYA--SPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGAGFNFGKTVSE
|.||. .|. | |. ||.. |. .|.|.|||||| | || .|. . | | . |.||.||| |. | ||.|| || | .
yeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnvid
EFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPA
. . |. .| ||||....|. |...|||||| || | | .. .|.|| . . |.
dvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpe
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 27-265 | 7.3e-50 | 162.9 | In-house | 4-266 (290) | alignment | ||
Range on Protein: 27-265
Range on HMM: 4-266/290.0
LLCEKAKEILSQESNVREVSCPVTVCGDVHGQFYDLL----ELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQ
||..| .|| .| .. |. |. | ||.||.. || |.|.| .. ...||.||||||| |||| .. |.|||| || .. .|||||| . ...
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqe
VYGFYDECLRKYAS--PAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATT---LDAIRDM-DRFQEVPHEGPM-CDLLWSDPDDR------------
. .. |. |. || |.. ||.|||. ..|..|| |.|. . | . ||.|. .|... . |. |.|||||..
sieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvln
AGW--NvSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYR
.|. | . || | |.. | | . |.| . |||. .|.. .. ..|.||. .||
eGfvdn.drrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 32-294 | 2.2e-70 | 230.3 | In-house | 18-280 (280) | alignment | ||
Range on Protein: 32-294
Range on HMM: 18-280/280.0
AKEILSQESNVREVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECL
. |. .|||. | .|. | ||.| |. |. || . | || . .|.||||||| .| . ||..||.|| .|| .||||||. . ..|||| ||
veaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecq
RKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGAGFNFGKTVSEEFNRTNG
||. ..| | |. .|..||. ....|.||||||. ||.||.. | | | . ||||||| .. || | || . ||| | |. ..
ykygv.glwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqacksle
LRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDPAPRPQG
. .| ||||.| .|.. | ..|.|| |||| . | .. |. |. || | | | |.|
idliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlippplpeg
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 44-288 | 1.7e-55 | 181.5 | In-house | 4-255 (263) | alignment | ||
Range on Protein: 44-288
Range on HMM: 4-255/263.0
EVSCPVTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKYAS----PAV
|. .|. .||| |||. ||| .| | .|.|||.||||||| .|.| . ||..||. | .. .|||||| . | . |||. | ... .|
elqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesv
WTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPM-CDLLWSDPDD-RAGWNVSP-RGAGFNFGKTVSEEFNRTNGLRIIAR
. .| ..| ..|| .| ..|.|.|||.||. .|| || . | . |. |||||.||. |.. | ||| ... . . .| |
ynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivr
AHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
|||.| |. . || ..|.||| | | .. .. |. ||.| |
ahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkp
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 48-240 | 8.3e-40 | 130.2 | Pfam-A | 2-198 (200) | alignment | ||
Range on Protein: 48-240
Range on HMM: 2-198/200.0
PVTVCGDVHGQFYDL----LELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLL--VALKVRYPERISILRGNHESRQITQVYGFYDECL----------
...|.||.||...|| |.|..|..| . ...||.||.|||| | | || .||...| .. |||||||......|||..|.|
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
-----------------------RKYASPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTLDAIrdmdrfqevphegpmcdllwsdpddragwnv
... . .. .. . |..||| ||. .|.. ||.||. . | |
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
sprgAGFNFGKTVSEEFNRTNGLRIIARAHQL
....||. . |.. . .|. .. |.|.
....gselfgpdalekllekygvdlvlrGHtH
|
|||||||||
PPP_2 | 49-240 | 3e-76 | 248.5 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-197/198.0
VTVCGDVHGQFYDLLELFRIGGEVPHTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDLFD
||||||.|||..|||.||. |...|...|||.|||||||..|.| ..||.|||..||... .|||||||.....||||..|.|.|. . .|.......|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
FLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVPHEGPMCDL-----LWSDPDDRAGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQL
.|||. |........|||||.. ..|| |. ..|..|.|.||...|| |....... ... | ||||. ||. |.||. ..| |..| |||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
PPP_4 | 49-240 | 1.5e-72 | 236.8 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-196/197.0
VTVCGDVHGQFYDL-LELFRIGGEVP-HTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKyASPAVWTYFTDL
|||.||.|||..|| |.|...||. . ...|.|.|||||||..|.| ..||.|||..||... .|||||||......|||..|.|.| . .. ...|.
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVP-HEGPMCDL-LWSDPD-DRAGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQL
||.|||. |........|||||.. ..|| |....|..|.| .|. ..|| ||||| . |.. | ||||. ||..| |.| ..|.|..| |.|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
PPP_5_Dcr2 | 49-240 | 3.5e-70 | 229.0 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-198/199.0
VTVCGDVHGQFYDL-LELFRIGGEVP-HTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKYASPAVWTYFTDL
||||||.|||..|| |.||. ||. . ...|.|.|||||||..|.| ..||.|||..||... .||||||..|....|||..|.|.|| . .. ...|.
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FDFLPLTGLVERQIFCLHGGLSPQATTLDAIRDMDRFQEVP-HEGPMCDL-LWSDPD-DRAG-WNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQL
||.|||. |........||||||. ... .....|..|.| ..| ..|| ||||| . | . | ||||. ||..| |.| ..|.| | |.|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_YNL217W_pd | Subfamily YNL217W | 49-122 | 1.4e-07 | 24.3 | In-house | 12-81 (235) | alignment | ||
Range on Protein: 49-122
Range on HMM: 12-81/235.0
VTVCGDVHGQFYDLLELFR--IGGEVPHTNYLFMGDYVDRGYFSVEAVTLLvalkvrYPERISILRGNHESRQITQ
. | ||||| . .|.||. ||| . ...|| ...| |||.| .. . ..|||| . .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvlla
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 74-288 | 3.1e-71 | 233.1 | In-house | 100-314 (317) | alignment | ||
Range on Protein: 74-288
Range on HMM: 100-314/317.0
HTNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKYaSPAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATT
. .|||.||||||| ||.| |.||.|||..||... .|||||||| . . |||| |. ..| | |.. | | |||. .|. .|.|.|||.| . .
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry.saalyeafqlafnvlplcavvnkkilcmhGGiseelld
LDAIRDMDRFQEVPHEGPMCDLLWSDPDDR-AGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGI
|. . ..| ..| | ..|| |.||| . |.. |.||||. ||.. .||... | .. ||||.|..|... ||..|||||||.|| . | . .
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav
MELDDTLNYSFLQYDP
...|. |. |. . |
lsvdkklkisinvlrp
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 75-290 | 2.8e-55 | 180.8 | In-house | 120-335 (339) | alignment | ||
Range on Protein: 75-290
Range on HMM: 120-335/339.0
TNYLFMGDYVDRGYFSVEAVTLLVALKVRYPERISILRGNHESRQITQVYGFYDECLRKYASpAVWTYFTDLFDFLPLTGLVERQIFCLHGGLSPQATTL
|||.||||||| ||.| | || |||. ||.|| .|||||||| . |||| | .| . .. | ..|. .|. ... |.|.|||.| . |..
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsf
DAIRDMDRFQEVPHEGPMCDLLWSDPDD-RAGWNVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIM
. . . | |.| | . || |.||| |.. | ||| | || | . |... | ||.| .|... | .|||||||||| . | ..
nqfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavf
ELDDTLNYSFLQYDPAP
.| |. | . |
sidkklkisinvfrpes
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 192-288 | 7.2e-21 | 67.3 | In-house | 237-334 (383) | alignment | ||
Range on Protein: 192-288
Range on HMM: 237-334/383.0
MCDLLWSDPDDRAGW-NVSPRGAGFNFGKTVSEEFNRTNGLRIIARAHQLVMEGFNWSHDRNVVTIFSAPNYCYRCGNQGGIMELDDTLNYSFLQYDP
. |.||||| . | . ||.| || |.... . .|... |.|. .||....||..|.||||| || |.| . | ..|. ..||
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqa
|