Gene PPP3C-2 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP3C
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP102_AA protein Get Run
MbreP102_AA_45-248 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP3C_pd Subfamily PPP3C 2-411 3.8e-225 740.8 In-house 24-430 (452) alignment 
Range on Protein: 2-411
Range on HMM: 24-430/452.0
DKPNLDVLQQHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKI
.||.|.||..|.|.|| ..|.||||... .......|.||||.|||.||.||.|||||||.|||||||||.||.|||||||||||||||||||||.||||
gkpklevlkehflkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalki

IYPKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKD
 ||....||||||||||||||||| .||..||||.||||||||||.||||||||.||||||||||||...||||| .|||.||| |||.|||||.||..|
aypstlfllrGnhecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPled

YGQNSTSQQFQYNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNADTGFPSLITLFSAPNYLDMYNNKAAIMKYDSNVMNIRQFNSSP
||...|...|..|..|||||.....|.|.||..|.||||||||||||||||||.|.  |||||||||||||||||.||||||..||..||||||||||||
ygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennvmnirqfnssp

HPYWLPNFMDVFTWSLPFVAEKTTDMLFHILTAALQAEPVPERELTpeEQKEAEKERRREAVRQKIRAIGKMARMFSTLREESETVLVLKGLSdTGALPR
|||||||||||||||||||.||.|.||..||. . . | . |.| .  ...|.|.|.|.|..|.|||||||.||.|| ||||||.||.||||. ||||||
hpywlpnfmdvftwslpfvgekvtemlvnilnicsddelekeeeee..skeesesekrkevirnkiraigklarvfsvlreesesvlllkglt.tgalpr

GSLLAGKEGL
|.| .|||||
galsegkegl
0045823 Metallo-dependent phosphatases 2-412 1.3e-140 462.0 In-house 26-432 (473) alignment 
Range on Protein: 2-412
Range on HMM: 26-432/473.0
DKPNLDVLQQHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKI
....||.| .||. ||...|  .|||.. ...|.  |..|||.... .|.||.|||..||..|.|  | |...|..||||.||||..|.|....|.||||
glldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalki

IYPKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKD
 ||....|||||||.|.|. .. |. |.  ||.||.|....| ...|||||...|..|.|||||||....||.|..|.|..|.| .|...||||.||  |
kypgnvfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed

YGQNSTSQQFQYNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNADTGFPSLITLFSAPNYLDMYNNKAAIMKYDSNVMNIRQFNSSP
 |.. .   |  |. ||..|.|...| . ||..|.|  |.|.|.... ||... ..  .|....||.||||||.....|.||....|.......||. ||
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedlisfiqfdpsp

HPYWLPNFMDVFTWSLPFVAEKTTDMLFHILTAALQAEPVPERELTpeeqKEAEKERRREAVRQKIRAIGKMARMFSTLREESETVLVLKGLSDTGALPR
||..||.|.|||..||||. || |..|...|..  . |  .. ...    ..   | ..|..|.||.|.||..|.||.||||||.|| ||||...| ||.
hplilplfldvfllslpfllekltellllllnivsddellededil....glllleallellrnkilalgkllrvfsvlreesesvlllkgltpsgllpl

GSLLAGKEGLM
| || ||| |.
gllllgkelll
0049330 Metallo-dependent phosphatases 4-306 9.9e-97 316.7 In-house 15-305 (309) alignment 
Range on Protein: 4-306
Range on HMM: 15-305/309.0
PNLDVLQQHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIY
..||.| ..|| ....||. .|.|.. ...|. .|..|||.... .|.||.|||..||..|.|  | |...|..||||.||||..|.|..|.|.|||. |
slldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalklly

PKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYG
|....|||||||.|.|. .. |. |.. ||.......... ...|||||...|..|||||||||....||.|....|..|.|  |..|||||.||  .. 
pdnvfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpire

QnstsqqFQYNAaRGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNAdtgfpsLITLFSAPNYLDMYNNKAAIMKYDSN-VMNIRQFNSSPH
       |. |  ||....|.| | ..||..|.|  |||.|.|.. ||... ..       |||.||||||.....|..|....|.. |.....|. .|.
g......fapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgk......litvfsapnycgrlgnlgavleidedlvisfllfepvpl

PYWL
...|
llll
0053225 Metallo-dependent phosphatases 4-293 3.1e-90 295.5 In-house 7-284 (293) alignment 
Range on Protein: 4-293
Range on HMM: 7-284/293.0
PNLDVLQQHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIY
..||.| ..||   ..||. .|.|......|.  |..|||.... .|.||.||...||..|.|  | |...|..||||.||||..|.|....|.|||. |
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly

PKSIYLLRGNHECRHLTEYFTFLTECQVKY-SEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDY
|....|||||||...|. .. |  |.  || .....|.... ...||||||..|..|.|||||||.. .||.|. |.|....|  |...|||| ||   .
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws

GqNSTSQqfqynaaRGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKnadtgfPSLITLFSAPNYLDMYNNKAAIMKYDSN-VMN
|   .|.       ||....| | | . ||..|.|  |||.|.... ||... .      ..|.|.|||||||....|..|....|.. |..
g.wlpsy.......rglgvvfghtavlrflkkngldliirghqvvpdgylpwfd......gklvtvfsapnylgrlgnlgavlaldeglvwg
subfamily_PPP2C_pd Subfamily PPP2C 6-302 2.5e-84 275.9 In-house 4-288 (290) alignment 
Range on Protein: 6-302
Range on HMM: 4-288/290.0
LDVLQQHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPK
|| | ..|     ..|.   .|     .|.. || . |...|.||||||||||.||..|| .||.   | ||||||||||||.|.|.| .| |||. |..
ldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvryke

SIYLLRGNHECRHLTEYFTFLTECQVKYSE-DVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYGq
 | .|||||| | .|. . |  ||  ||.. .|.    . || |||.||...| .|.||||||...|||.|.|.||.|| |  ||.|||||.||    | 
ritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrgg.

NSTSQqfqynaaRGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNAdtgfpsLITLFSAPNYLDMYNNKAAIMKYDSNV-MNIRQFNSSPH
 ..|.       ||. | | .. | .| ..|.|  |.|||.    ||..  ..       ..|.||||||     |.|||.. | .. ... ||...|.
wgisp.......rgagytfgkdisekfnktngltliarahqlvmegynwshdrn......vvtifsapnycyrcgnqaailelddklkysflqfdpapr
subfamily_PPP5C_pd Subfamily PPP5C 11-305 1.3e-80 263.9 In-house 26-314 (322) alignment 
Range on Protein: 11-305
Range on HMM: 26-314/322.0
QHLLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAP----MTVCGDVHGQFYDLMKLFEVGGDPKS-TRYLFLGDYVDRGYFSIECVLYLWALKIIYPK
... ..  . .. |||...  .........|.||. .    .|||||.|||||||. .||. | | .   ||| ||.|||| ||.|..| |...|..||.
elfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPn

SIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLS-PEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYGQ
...| |||||  .. . . |  |.. ||.| |.|   |.|. |||| ..| ..| |||||   .  ||||.. |||...|| .| ...|||.|| .  |.
hfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanGr

NStSQqfqynaaRGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKY--DSNVMNIRQFNSSPH
.. |.       || . .|  . .  ||. |||  |||.|| .. ||.. ..       .|||.|||||| |  .||.|...   | . .....|.. .|
sp.sk.......rGvgvqfGpdvtkkflkennleliirshevkeeGyevehdG......klitvfsapnycdqmgnkgafitlrgddlklkfktfeaveh

PYW
|  
pdv
subfamily_PPP4C_pd Subfamily PPP4C 13-292 2e-86 282.8 In-house 10-276 (288) alignment 
Range on Protein: 13-292
Range on HMM: 10-276/288.0
LLAEGVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRG
|    ...|.   .| .   .|. .|| . ....|.|||||.|||||||..||.|||| ..|.||||||.||||..|.|. | | |||. ||. |.|.||
lrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirg

NHECRHLTEYFTFLTECQVKY-SEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYGQNstsqqf
|||.|..|. . |  ||  || | .|.  |.| || |.|||...|. .||||||||...|||.|..||| || | .||.|||||.|| .  | .      
nhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwa......

qyNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
   . ||  | | .... .| ..|..  |.|||.    ||... ..      ...|..|||||     |.|||...|... 
..vsprgagylfgsdvveqfneandielicrahqlvmegyklhfne......kvltvwsapnycyrcgnvaaileldeeld
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 14-290 1.3e-62 204.8 In-house 19-284 (297) alignment 
Range on Protein: 14-290
Range on HMM: 19-284/297.0
LAEgVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGN
|.. |..|.  |||. |. ..|. . ...|..||. ||||.|||| ||..||  || | .. ||||||||||| |||| .. | | |. .|  ..|||||
lsk.viteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgn

HECRHLTEYFTFLTECQVKY-SEDVYDACMESFDALPLAALLNGQFLCVHGGLSP---EVQTLDDIKAIDRFQEPpPSGPMCDLLWADPAKDYgqnstSQ
|||  . . . |  ||| .| |  .| |  . |. |||. |.  . ||.||||||   .  ||| .. |.| .|    . ..|||||||         | 
hecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisgl.....sg

qFQyNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSN
 |  .  ||.   | ..|        .|  . |||.  . || ..          |.|.|||| |   ..| ||.|  | .
.fm.enqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagr......klvtifsaphycgqfdncaafmscdek
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 17-292 2e-78 256.4 In-house 22-285 (298) alignment 
Range on Protein: 17-292
Range on HMM: 22-285/298.0
GVVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHEC
 |..|.   || .|...||.. ..|.|..||..||||.|||. ||..||. .| |... ||||||||||| ...| .. | | |. ||. ..||||||||
kvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnhec

RHLTEYFTFLTECQVKY-SEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKdygqnsTSQQFQYNa
 .. . . |  ||. .| |  .| .  . |.||||.||. |. ||.|||||.....||..... | .... .    |||||||..      . .... | 
eainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpen......avkgwaen.

ARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
.|| |. | ...   .| . ..  ..|||     || .. ..       |.|.||||.|.. ..| ||.|| |....
srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaek......klvtifsaphycgqfdnsaavmkvdeklv
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 18-292 1.7e-67 220.8 In-house 23-285 (299) alignment 
Range on Protein: 18-292
Range on HMM: 23-285/299.0
VVSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECR
 | ||   .| ... ..| ....|||.|||. ||||.|||. ||...|.. | |  . .||||||||||   .| .  | . || ||. ...||||||| 
svkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecp

HLTEYFTFLTECQVKY-SEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKdygqnsTSQQFQYNaA
 .   . |  ||. .| |  .. .  ..|.|.||. |.... ||.||||||..|||| .. . | |.||      ||||||| .      . .... | .
ainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdq......svkdwlan.v

RGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
|| || | ..     . | ..  . |||.  . || .. ..       |.|.|||| |   ..| ||||| | |..
rgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffask......klvtifsaphycgqfdnsaaimkvdenlv
subfamily_PPP6C_pd Subfamily PPP6C 19-298 3.2e-76 249.2 In-house 15-282 (290) alignment 
Range on Protein: 19-298
Range on HMM: 15-282/290.0
VSEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRH
..|. . ||  | .... .||..  ...|.|||||.|||||||..||  ||.   |.|.||||.|||||.|.| . .| .||. ||. | |||||||.|.
lpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

LTEYFTFLTECQVKYSE-DVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPaKDYGQNSTSqqfqynaAR
.|. . |  ||. || . ...  |.. || |..||....| |||||||||.|.|||.|. |.| || |  |..|||.|.|| .|  . ..|        |
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edvetwavs.......pr

GCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNAdtgfpsLITLFSAPNYLDMYNNKAAIMKYDSNV-MNIRQFN
|  | | .. . .|.. |||  |.|||.  . |.. . ..       |.|..|||||     | |.|.. . .   . . |.
gagylfgskvtkefvhinnlklicrahqlveeglkymfdek......lvtvwsapnycyrcgnvasilaledaeereaklfk
PPP_3 20-293 1.6e-95 312.2 In-house 3-264 (271) alignment 
Range on Protein: 20-293
Range on HMM: 3-264/271.0
SEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHL
||. . .| . ...|.. ||.|.||.||.|||||.|||..||..||..||....|.|||||||||||..|.|..|.|.|||| |||...|||||||.|..
senelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqi

TEYFTFLTECQ-VKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAkdygqnsTSQQFQYNAARG
.....| .|..  |....||....| |..||||||.....|.|||||||....||.|| ..|..| | .|...|||. ...       .....  |..||
nkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdp.......ekeeglenskrG

CSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKnadtgfPSLITLFSAPNYLDMYNNKAAIMKYDSNVMN
....|.......||..|.|  ||||||....||.....       ...|.||||||.. ..|..||.| ... ..
agllFgpdvteefleknkLkliiRaHelkeeGyeilhd......gkvvtvfSapnycerasnagailkleealts
subfamily_PPP1C_pd Subfamily PPP1C 20-292 1.9e-86 282.8 In-house 11-270 (282) alignment 
Range on Protein: 20-292
Range on HMM: 11-270/282.0
SEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHL
.|.   .| .   .|......|||.|||....||.|||..||..||| .| |....||||||||||| .|.| .. | |.|| ||....|||||||. ..
keaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesasi

TEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDygqnstSQQFQYNAaRGC
.... |  ||. .|| ... . .. |. ||||||.. . ||||||||||.. |..|. | |  | | .| .|||||.|| |.      ..... |. || 
nriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdke......vlgwsend.rGv

SYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
|. | ...  .||..|.|  |.|||.  ..||....|.       |.|.||||||.....|..|... |....
sftfgkdvvekflqkndldlivrahqvvedGyeffakr......qlvtvfsapnycgefdnagavlsvdeell
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 20-288 1.4e-57 187.9 In-house 17-276 (290) alignment 
Range on Protein: 20-288
Range on HMM: 17-276/290.0
SEQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHL
|..  |...    .|..   .|||.|||... ||.|||. .|.. |.  | |   ..||||||||||  |.|  |.|. .|| |.|...|||||||.|..
sdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkv

TEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPP--PSGPMCDLLWADPAKDygqnsTSQQFQYNAAR
   . |  |   | .  ..    . |. |.| | .. . ||.|||.|..... . .||. . . |     | . |||||||..|      .. ...|  |
nrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd.....kddtialnkqr

GCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYD
. |  | ...  ..|..  |  |.|||| .. |. .  ..       |.|.|||| |     |  ||..  
aisvvfgkkglddllkklalslivrahevkeegfnflfdk......klvtvfsapyysgndtnlgaiatvs
PPP_1 21-286 5e-102 333.7 In-house 3-263 (264) alignment 
Range on Protein: 21-286
Range on HMM: 3-263/264.0
EQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLT
|. . .| .  ..... |..|||.....|||||.||||.||.|||.|||....|.|||||||||||..|.|..|.|.|||. |||...|||||||.|..|
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt

EYFTFLTECQ-VKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYGQNSTSQQFQYNAARGC
....| .|..  |||...|......|| ||||||.....|.||||||||...||.|. ..|..| | .|..||||..|  ... ........  |. ||.
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa

SYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMK
.|.|.......||..||| .||||||....||....|.      ...|.|||.|| .  .|..|..|
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkr......kvvtifsasnyyeegsnrgayvk
PP2Ac_SM00156 21-293 2.4e-100 328.1 In-house 3-262 (271) alignment 
Range on Protein: 21-293
Range on HMM: 3-262/271.0
EQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLT
.. .|.|   . .|.. |..|.|..|| ||.||.|||..||..|.| .| |....|.|||||||||..|||..|.|.||||.||. ..|||||||.....
keevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvn

EYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPakdygqNSTSQQFQYNAaRGCS
....|  |.. ||....|. ..| |..||||||.. ..||.|||||||...||||. ..|..|.| .|...||||.||      ... ..|| .. ||.|
kiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdp......eqkekgfqpsk.rgls

YYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVMN
..|...| . ||..|||  ||||||..| ||... ..      .|.|.||||||.| ..||||..|...|.. 
vvFgedavkeflkknnlkliiRahevvdeGyeffadk......klvtifsapnycdefsnkaavlkveknlkl
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 21-288 8.4e-68 221.4 In-house 12-269 (287) alignment 
Range on Protein: 21-288
Range on HMM: 12-269/287.0
EQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLT
..  |...    .|..  ..|||.|||.|..||.|||. ||...|.  | .  ..|||||||||||  |.| .|.|..||| |||...|||||||.... 
dkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkin

EYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPS--GPMCDLLWADPAKDygqnstSQQFQYNAARG
. . |  | . |..| .|    . |. ||| | .. . ||.|||.||....||..||. . . |     | . ||||||| ||      .. |. |  |.
klyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd......aktfelnkira

CSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYD
 |  | ..   ..|.. ..  |.|||| .. || .. ..       |.|.|||| |     | .|... .
isvvfGkkevddllkkldidlivrahevseeGyaflfdk......rlvtvfsapyysgedtnlgavvvvs
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 21-291 2.4e-59 194.0 In-house 8-290 (302) alignment 
Range on Protein: 21-291
Range on HMM: 8-290/302.0
EQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGD-----PK------STRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYL
..  |.|    .. .. |.|| || .|.|. ||.|||| ||....    .      |      | ...|||||||||. ||||.  ..|||..||.   |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHECRHLTEYFTFLTECQVKYSE----DVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQ-EPPPSGPMCDLLWADPAKDYGQ
||||||.. .   ..|  | . ....    ....   | |  .|||||.  . ||||||.|| ...|.||| |.|   |  .     |||.|||.   . 
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

NSTSQ--QFQYNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
 ..|.  ... |  || |. | . |   . .| ||  |.|||    .|.... ..       |.|.||||.|..  .|| |..| |.| 
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadk......klltifsaprymnesdnkGavlkvdtng
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 21-291 3.8e-59 193.3 In-house 9-291 (302) alignment 
Range on Protein: 21-291
Range on HMM: 9-291/302.0
EQAALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGD-----PK------STRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYL
..  |.|    .. .. |.|| || .|.|. ||.|||| ||....    .      |      | ...|||||||||. ||||.  ..|||..||.   |
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyil

LRGNHECRHLTEYFTFLTECQVKYSE----DVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQ-EPPPSGPMCDLLWADPAKDYGQ
||||||.. .   ..|  | . ....    ....   | |  .|||||.  . ||||||.|| ...|.||| |.|   |  .     |||.|||.   . 
lrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqll

NSTSQ--QFQYNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
 ..|.  ... |  || |. | . |   . .| ||  |.|||    .|.... ..       |.|.||||.|..  .|| |..| |.| 
aavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadk......klltifsaprymnesdnkGavlkvdtng
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 24-291 8.7e-69 224.7 In-house 11-265 (280) alignment 
Range on Protein: 24-291
Range on HMM: 11-265/280.0
ALKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYF
  ..   |..|.. ..|..|..||..||||.|||. ||..||.  . |  . ||||||||||| . .| .| | | |. ||.....||||||. .. . .
idrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisinrky

TFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYGQNStsqqfqyNAARGCSYYF
 |  |.. .||...|.   | .| |||.||..|. ||.|||||.....|||.. . |  ... .    |||||||...    .       ...||.|. |
gfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwa.......ensrgvsvif

THEASCSFLRRNNLLSIIRAHEAQDAGYRMYeknADTgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
 ..    . .. ..  |.| |.  . || ..   ||     |.|.||||.||. ..|.||... |...
ganvvkdltekldidliarghqvvqdgyeff...adk...klvtvfsapkylgefdnsaavlivderl
subfamily_PPG1_pd Subfamily PPG1 25-291 4.8e-76 248.9 In-house 20-286 (300) alignment 
Range on Protein: 25-291
Range on HMM: 20-286/300.0
LKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFT
 .|     ... .|| . ||..|.|| |||||||||....|..||.   | |||||||||||..|.| .  | .||. ||  | ||||||| | .|. . 
keltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqitqvyg

FLTECQVKY--SEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKD----YGQNSTS-QQFQyNAAR
| |||  ||     |..   | || | |||... .  ||||||||.|...|.|| .|||.| |  | ..||||.|| ..      .   . |.|. .. |
fyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhfv.vsqr

GCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
|. | . ..    ||| |..  |||||.    ||...  |       | |..|||||     |||.|..  .. 
gagysygkdvvekflrnndmnriirahqlcnegyqilfdn......klstvwsapnycyrcgnkasilelyekd
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 25-292 2.7e-66 216.9 In-house 14-274 (284) alignment 
Range on Protein: 25-292
Range on HMM: 14-274/284.0
LKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDP------KSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRH
..|   . ..|  |.  ||||||....||.|||| ||. |... | |      |...||||||||||| |||| .. |.|.|...|. ..||||||| | 
ielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnhesrp

LTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYgqnstsQQFQyNAARG
.   . | .||. .||| .|.|   .| |.||.|... . .|.|||.| ..  |.......|  . |  | ..|| |||| ..       .... .. ||
vnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaev......egyk.esprg

CSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYeknADTgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
.   | ..|   ||.. .|  ..|||.    || ..   ||     |.|.|||| |   ..| ||... |....
agkvfgakavkeflkkfkldlvvrahqvvmdgyeff...adr...klvtifsapsycgqldniaavlnvdeelv
subfamily_PPZ_pd Subfamily PPZ 25-288 5.2e-61 199.8 In-house 31-281 (300) alignment 
Range on Protein: 25-288
Range on HMM: 31-281/300.0
LKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFT
|..   . ..|  . .|||.  .. . ||||||. ||..||   | | |. |||||||||||  |.| .| |.. || ||. ..||||||||  .|  . 
lqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecanvtrvyg

FLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKdygqnsTSQQFQYNaARGCSYYFT
|  ||. .    .. . ...|..|||||.. |. .|||||||| ....|.|. . |  . |  | . ||||.||.       .|.... |  || || . 
fydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptd......ssnewedn.ergvsycyn

HEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYD
. |   || .  .  . |||   . || ...        ||.|.||||||   ..|  |.|   
kvainkflnkfgfdlvcrahmvvedgyeffndr......slvtvfsapnycgefdnwgavmsvs
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 25-296 2.1e-57 187.7 In-house 12-271 (280) alignment 
Range on Protein: 25-296
Range on HMM: 12-271/280.0
LKLFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFT
. .  .   || .|| | | |||. | ||.| |. |. .||.. |     . .|||||||||   || .. |..||| |   |||||||||   . . . 
iaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiyg

FLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDyGQNstsqqfQYNAARGCSYYFT
|  ||| ||   ..      |. .|...|.. . ||.|||||||.  || |. | |  ||   | . ||||.||..  |.        . . || || | 
fyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnk.geg......wfhsirgisymfg

HEASCSFLRRNNLLSIIRAHEAQDAGYRMYeknadTGfPSLITLFSAPNYLDMYNNKAAIMKYDSNVM-NIRQ
.       .  ..  |||||.  . || |      .|   |||.|| |||   . | ||..  ..|.  ...|
kgvveqacksleidliirahqvvqdgyemm.....ag.rrlitvfsvpnycaqftnaaavvclnanlqvsfqq
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 27-291 1.6e-61 201.2 In-house 11-264 (284) alignment 
Range on Protein: 27-291
Range on HMM: 11-264/284.0
LFTLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFL
|.  . .||. .  |.|...|. .|||.|||| ||..||.  | |. . |||||||||||   .| .| |.| |.|.|. ...|||||||  . . . | 
llfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfy

TECQVKYSE-DVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDR-FQEPPPSGPMCDLLWADPAKdygqnstSQQFQYNAARGCSYYFT
 ||| .| .  || .    |  .||.||.  . ||.|||.|  .| . ...|| | |..| |     |.||.||..        |.     .|| || | 
eecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptn.......fqkgwnpnsrgvsyvfg

HEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
 .|   .| | ..  ..|||.  . || .. .        |.|.|||| |   ..| ||.|  . |.
sdalrklldrlqidlvvrahqvvqdgyeffanr......rlvtifsapfycgqfdnaaavmyvnknl
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 29-73 1.5e-10 33.8 In-house 19-63 (317) alignment 
Range on Protein: 29-73
Range on HMM: 19-63/317.0
TLCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKS
    ..|  |   ||.|||.|..||.|||| ||. |... | | |
yrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 30-291 1.5e-66 217.5 In-house 19-267 (281) alignment 
Range on Protein: 30-291
Range on HMM: 19-267/281.0
LCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTEC
    || .|..| ||..|..| ||.|.|| || .|||. | .  ....|||||||||  |.|... |..||| |.. |.|||||||  ..   . |  ||
eveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnkiygfyvec

QVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAkdygqNSTSQQfqYNAARGCSYYFTHEASC
..|| |...    . |. ||..|| . . ||.|||||||. .||... . .  ...  | . |||||||      |.. .   ....|| |. | ..   
vtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpd.....nkveew..kassrGssftfGknvvd

SFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNV
   .| ..  |||||    .||.. .         |||.||.||| ..|.| ||..| | ..
dvckrleveliirahqvvqdGyevlsgr......klitvfsvpnycafyknaaavlkvdetl
subfamily_PPPLV_pd Subfamily PPPLV 30-292 5.7e-59 192.8 In-house 8-281 (290) alignment 
Range on Protein: 30-292
Range on HMM: 8-281/290.0
LCTNIFQDESTLLEIEAPMTVCGDVHGQFYDLM----KLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTF
   .|. .|  |||...|. | ||.||.. ||.    .|. .| |   . .|||||||||| ||.| . || |||..||  ..||||||| . ..| ...
vavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesiey

LTECQVKYS---EDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAI----DRFQEPPPSGPM-CDLLWADPAKDY-----GQNSTSQQFQ
 .|.. |.    |.|..| .. |||||||| .. . .|||.|.   ..|   | ||    .|....    |.  |.||.|||.|      |. .... | 
kgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGfv

YNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSNVM
 |  || .. |...|  .||.||||  ..||||....|.|. .|        |.|.||. .|    |. | |.   ... 
dndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkg......rlltvfsssrycGssneaalilvdkkklr
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 32-290 1.1e-50 165.6 In-house 33-281 (307) alignment 
Range on Protein: 32-290
Range on HMM: 33-281/307.0
TNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQV
  ||  | .|..|. |  | ||.|||| ||...| . | |  | |.| ||||||| .|.||.| |.. ||.||..| |||||||  .. . ..|  ||  
qtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvt

---KYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLWADPAKDYgqnstsqqFQYN-AARGCSYYFTHEA
   |  |...      |. ||..||.  . ||.|||||| .  ||...   .    |  | . |.|||||            |... ..||  . |  . 
sipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsv........fewkassrgsgftfgtnv

SCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDSN
     .|  .  |||||.    || .           |||.|||| | ..|.|  ...| |  
iddvckrlgveliirahqmcfdgywvlsgr......klitifsapmycnfyknagcvlkvdet
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 32-74 3.6e-07 22.6 In-house 24-66 (339) alignment 
Range on Protein: 32-74
Range on HMM: 24-66/339.0
TNIFQDESTLLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKST
 ..   |  .|..|||. | ||.|||| ||. .... | | |.
reliwsepiflkleapicvmgdihgqfddllamldmngwplss
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 41-285 6e-52 169.9 In-house 2-240 (263) alignment 
Range on Protein: 41-285
Range on HMM: 2-240/263.0
LLEIEAPMTVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVKYS-EDVYD
|||..||. .||| |||. ||...|.  |    |.||||||||||| .|.| .. |..||.  |. ..||||||| . . . . | .| . ..  |.||.
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

ACME----SFDALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPM-CDLLWADPAKDygqnstSQQFQYNAARGCSYYFTHEASCSFLRR
.  .     |  .||.|... . ||.|||.|| ...||||.||    |   . |. |||||||| ||      .. |. |  |  |  | ..    . .|
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekd......akgfepnkiraisnvfgkkevddlckr

NNLLSIIRAHEAQDAGYRMYeknADTgfpSLITLFSAPNYLDMYNNKAAIM
 ..  |.|||.  . || ..   ||     |||.|||  |     | ||..
ldidlivrahqvveygyaff...adr...rlitvfsasryqielcnyaavv
subfamily_PPP7C_pd Subfamily PPP7C 44-180 7.3e-33 106.8 In-house 62-201 (383) alignment 
Range on Protein: 44-180
Range on HMM: 62-201/383.0
IEAPMTVCGDVHGQFYDLMKLFEVGGDPKS-TRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVKY---SEDVYD
|   .|||||.||.. ||. ..   | | .   |.| ||.||||  |.| .| | || ..|||..|| |||||   |   . |. | . ||   ....  
iskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilr

ACMESFDALPLAALLNGQFLCVHGGLSpEVQTLDDIKAIDR
   . |  ||||.|.. . | ||||.| .   |. .. |.|
lledvfawlplatlidekilivhGGis.dktdlelldkier
Metallophos Calcineurin-like phosphoesterase 48-247 4.9e-42 137.5 Pfam-A 3-199 (200) alignment 
Range on Protein: 48-247
Range on HMM: 3-199/200.0
MTVCGDVHGQFYDL----MKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYL--WALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQ-----------
 .|.||.||...||    ..|.......| . .|||||.||||  |.|.  .|  ..||. .|. ..|||||||........ || |.            
ilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangee

-----------------------VKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLDDIkaidrfqepppsgpmcdllwadpakdygqnst
                        ..  ...... | |.||||.|| .|..|..||.||.. .. |||                                
eyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi................................

sqqfqynaargCSYYFTHEASCSFLRRNNLLSIIRAHEAQ
           .|..|  .| . .|.....  ..|.|. .
...........gselfgpdalekllekygvdlvlrGHtHk
subfamily_YNL217W_pd Subfamily YNL217W 48-122 3.4e-07 23.0 In-house 12-82 (235) alignment 
Range on Protein: 48-122
Range on HMM: 12-82/235.0
MTVCGDVHGQFYDLMKLFE--VGGDPKSTRYLFLGDYVDRGYFSIECVLYLwalkiiYPKSIYLLRGNHECRHLTEY
. | ||||| . .|..|..  .||  .    ...|| ...|  |.| | |.        .  . ..||||   | .|
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllay
PPP_4 49-247 3e-73 239.1 In-house 2-197 (197) alignment 
Range on Protein: 49-247
Range on HMM: 2-197/197.0
TVCGDVHGQFYDL-MKLFEVGGDPK-STRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFD
||.||.|||..|| .||...||.|. ...|.|||||||||..|.|..|.|.|||. ||| ..|||||||...|.....| .|.. |............||
tvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvfd

ALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPP-PSGPMCDL-LWADPAkdygqnsT--SQqfQYNAARGCSYYFTHEASCSFLRRNNLLSIIR
 ||||||.....|.||||||.|...||.|..|.|..| |  .. ..|| ||.||.       .  ..    |..||....|.... ..||..||| .|||
llplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpr.......eaqeg..lansvrGagllFgpdvtekfleknnlkliir

AHEAQ
.||..
shelk
PPP_2 49-246 1.2e-72 236.7 In-house 2-197 (198) alignment 
Range on Protein: 49-246
Range on HMM: 2-197/198.0
TVCGDVHGQFYDLMKLFEVGGDPKSTRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQ-VKYSEDVYDACMESFDA
|||||.|||..||..||..|.......|||||||||||..|.|..|.|.|||. |||...|||||||.........| .|..  |....||....| |..
tvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfel

LPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPPPSGPMCDLLwadPAKDYGQNSTSQQFQYNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEA
||||||.....|.||||||.|...||.|| ..|..| | .|...|||   . ... ........  |.|||....|........|..|.|  ||||||.
LplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldll...eeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
PPP_5_Dcr2 49-246 7.9e-70 227.9 In-house 2-198 (199) alignment 
Range on Protein: 49-246
Range on HMM: 2-198/199.0
TVCGDVHGQFYDL-MKLFEVGGDPK-STRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVK-YSEDVYDACMESF
|||||.|||..|| ..||. ||||. ...|.|||||||||..|.|..|.|.|||. ||| ..|||||||...|.|...|..|.. | .....|... ..|
tvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdvf

DALPLAALLNGQFLCVHGGLSPEVQTLDDIKAIDRFQEPP-PSGPMCDL-LWADPAkdygqnS-TSQQfQYNAARGCSYYFTHEASCSFLRRNNLLSIIR
| ||||||.....|.||||||||.........|.|..| |  .| ..|| ||.||.      . ...  . |. ||....|.... . ||..|||  |||
dwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdpr......daqegc.klnseRGagllfgpdvtekfleknnlkliir

AHEA
.||.
shel
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 74-292 4.7e-57 186.5 In-house 101-306 (317) alignment 
Range on Protein: 74-292
Range on HMM: 101-306/317.0
TRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLD
 .||||||||||| |||| |. | |||. ||. ..||||||| | .   . | .|.. .||. .|.|    | .|||.|..| . ||.|||.| |.  |.
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

DIKAIDRFQEPPPSGPMCDLLWADPakdygqNSTSQQFQyNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPN
 .....|  . |  | ..|| ||||      ... .... ..||| .  | ..|   ||.. .|  ..|||.    || ...         |.|.||||.
qldklkrpldipdvGvladltwadp......daevkgyk.esarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadr......klvtifsaps

YLDMYNNKAAIMKYDSNVM
|    .| ||... |....
ycGqldniaavlsvdkklk
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 74-291 7.1e-47 153.1 In-house 120-324 (339) alignment 
Range on Protein: 74-291
Range on HMM: 120-324/339.0
TRYLFLGDYVDRGYFSIECVLYLWALKIIYPKSIYLLRGNHECRHLTEYFTFLTECQVKYSEDVYDACMESFDALPLAALLNGQFLCVHGGLSPEVQTLD
 |||||||||||| ||.| |. | |||. ||  ||||||||| | .   . |  | . .|  ..|..  . |. .|..|..|   .|.|||.|  . ...
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfn

DIKAIDRFQEPPPSGPMCDLLWADPakdygqNSTSQQFQyNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPN
..  . |  | |  | . || ||||      . | . ..  .|||.|. |   |  .||.. .|  .|| |.  . || ...         |.|.|||||
qfsvfkrpleipdvgvltdltwadp......dptekgyk.psargasfvfgppalraflkkldlqmvirghqvvedgyeffdgr......rlvtifsapn

YLDMYNNKAAIMKYDSNV
|    .| ||..  | ..
ycgqndntaavfsidkkl
subfamily_PPP7C_pd Subfamily PPP7C 190-292 2.6e-13 42.4 In-house 237-326 (383) alignment 
Range on Protein: 190-292
Range on HMM: 237-326/383.0
MCDLLWADPAKDYGQNStsqqfqyNAARGCSYYFTHEASCSFLRRNNLLSIIRAHEAQDAGYRMYEKNadtgfpSLITLFSAPNYLDMYNNKAAIMKYDS
. |.||.|| .. | ..       |. ||   ||  . . ..|.. ||  .||.|| .  || .  ..       ..|.||| || ..  |. | .|  .
vldilwsdpkakeGckp.......ntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdk......kvltifsasnyyeeGsnrGayvklgk

NVM
...
dlt