Gene MbrePPM-Un-5 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP122_AA protein Get Run
MbreP122_AA_118-440 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 124-441 2.3e-31 101.9 In-house 26-291 (295) alignment
Range on Protein: 124-441
Range on HMM: 26-291/295.0
TSQHGSrhGKLNQDVPFCAS-FKQNGHRIAIAAVFDGHGllGEIAAAMARDTMTAL----QP--TFAWDSLLTQPEQGMREIFAQLDAAIVAAHDAPpaq
 |  |    | |.|  ..   .    . .....||||||  |  || .|....  |        .. ... |...|. .|..| ..| ....   .    
asdqGr..rksneDavlvvlnllslledlllfgvfDGhg..Ghaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr...

ytyigqsgsldfrleahaipeldppsgyvctsrdgvpPRPIDFGCTAVVAVVvDETHVVVGNAGDAAAFVLlRDQaghedrdgySVEALSVQHTARSKAE
                                     |. .  |.|||||..  .....|.|.||  |..| |..          .. |.| |.  .  |
.....................................pelagsGtTavvali.rgnklyvanvGDSravll.rng.........elvqltvdhkpvnele

QARVHETHPGAAHftgdgylapldpTLAQYELQLTRSLGHRLLK--------RAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLN---
..|. . ..   |                  |..||.||.. ||        . .|.| |.|..... ... . .. .|||..| ||  ...| | .   
rerilsaggavsh............grvngvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrslla

-AGTALEASEVLCQDAQDycmdETCIDDATAVVALFP
   .. ||.| |.. | .      . |. |.||. ..
kgldleeaaeeLvdlAla....rgsrDNiTvvvvrln

subfamily_Choan-PPM-1_pd Subfamily Choan-PPM-1 126-442 1.3e-193 634.2 In-house 1-317 (317) alignment
Range on Protein: 126-442
Range on HMM: 1-317/317.0
QHGSRHGKLNQDVPFCASFKQNGHRIAIAAVFDGHGLLGEIAAAMARDTMTALQPTFAWDSLLTQPEQGMREIFAQLDAAIVAAHDAPPAQYTYIGQSGS
.||||||||||||.|.||||..|||||.|||||||.|||||||||||||.|||.|...||||||.|||...||||.||||||||.|||||.|.|||||||
thgsrhgklnqdvyflasfklaGhrialaavfdGhsllGeiaaamardtltallPelvwdslltePeqllkeifarldaaivaaydapPaeyeyigqsGs

LDFRLEAHAIPELDPPSGYVCTSRDGVPPRPIDFGCTAVVAVVVDETHVVVGNAGDAAAFVLLRDQAGHEDRDGYSVEALSVQHTARSKAEQARVHETHP
||||||||||.|||||.||||.|||.||.||.|||.|||||||||||||||.|||||||.||||||||||||||.|||||||.||.|||||.|||.|..|
ldfrleahaiaeldpPkgyvcisrddvptrPldfGttavvavvvdethvvvanaGdaaalvllrdqaghedrdGlsvealsvrhtlrskaerarvaevlp

GAAHFTGDGYLAPLDPTLAQYELQLTRSLGHRLLKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCM
||||.|.|||||.||..||.||||||.||||.|||||||||||||||....|.||..||..||||||||..||||||||.|.||||||||||.|||||..
gaahvtedgylaildealaayelqltkslGhkllkraGviadPevrsrvldvdevfavvvvsdGitdelkrldvldrvlraataleasevlcddaqdyll

DETCIDDATAVVALFPA
|||.||||||||.|.|.
detsiddatavvlllpl

0049733 PP2C-like 128-440 1.4e-23 76.7 In-house 11-233 (235) alignment
Range on Protein: 128-440
Range on HMM: 11-233/235.0
GSRHGKLNQDVPFCasfkqnghRIAIAAVFDGHGllGEIAAAMARDTMTALQPTFAWDSLLTQPEQGMREIFAQLDAAIVAAhdappaqytyigqsgsld
  |. | |.|  ..         ....||.||||  |  |...|....  .   .  . ||...|. .|..| ....|...                   
igrvrkvneDavlv........glllfavaDGhg..ghaagevasellvetllelllelllldleealrkaflaaneallel..................

frleahaipeldppsgyvctsrDGVPPRPIDFGCTAVVAVVVdETHVVVGNAGDAAAFVLlRDQAghedrdgysVEALSVQHTARSKAEQARVHETHPGA
                          |     |.|||||... . ...| |.||  |..| ||.          .. |.. |.     |..|... ..  
......................alaspelagmgtTavvalld.ggklyvanvGDsrayll.rdgk.........lvqltedhspvnelerqriitaggav

ahftgdgylapldptLAQYELQLTRSLGHRLLKragviadPEVRSQTWPVGEvhGVVACSDGITDELSGLDVLDRVLNaGTALEASEVLCQDAQDycmdE
                  . |.|||.||..|||       |.|.. ..  |.   .. .|||..| ||  ...| . .  .. || | |.. | .     
...............rvpgrlaltralGdlllk.......pdvtvlelepgd..flllasDGlwdvlsdeeivdllrs.ldleeaaerlvelala....r

TCIDDATAVVALF
   |. |.||. .
ggrDNiTvvvvrl

PP2C_2 Protein phosphatase 2C 130-406 3.4e-09 29.3 Pfam-A 7-193 (212) alignment
Range on Protein: 130-406
Range on HMM: 7-193/212.0
RHGKLNQDVPFcasFKQNGHRIAIaAVFDGHGL--LGEIAAAMARDTMtalqpTFAWDSLLTQPEQG-MREIFAQLDAAIVAAHDappaqytyigqsgsl
| || .||  .   .... ..  . || ||.|   .....|..|  ..     . |  .||.. ..   .... |. ..| |. .               
rkgkpcqDala...ireasdgwll.aVADGaGsakrSdkGarlaveaa.....gealeklleeeseqeeeallrqieneilasvk...............

dfrleahaipeldppsgyVCTSR--DGVppRPIDFGCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQA----GHEDRDGYSVEalsvQHTARSKAEQARV
                     ..  ..    . |...| ..|| ......|... || |..| .||.     |..|  .|. |     . ..|.... ..
..................lkqeaeaqqe..elkdyatTlllav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel

hethpgaahftgdgylapldptlaqyelqltrslghrllkragviadpevRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNA
                                                  | ..... .. ... ..||. |.|.  . . ..|. 
..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae

PP2C_2 Protein phosphatase 2C 130-406 3.4e-09 29.3 In-house 7-193 (212) alignment
Range on Protein: 130-406
Range on HMM: 7-193/212.0
RHGKLNQDVPFcasFKQNGHRIAIaAVFDGHGL--LGEIAAAMARDTMtalqpTFAWDSLLTQPEQG-MREIFAQLDAAIVAAHDappaqytyigqsgsl
| || .||  .   .... ..  . || ||.|   .....|..|  ..     . |  .||.. ..   .... |. ..| |. .               
rkgkpcqDala...ireasdgwll.aVADGaGsakrSdkGarlaveaa.....gealeklleeeseqeeeallrqieneilasvk...............

dfrleahaipeldppsgyVCTSR--DGVppRPIDFGCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQA----GHEDRDGYSVEalsvQHTARSKAEQARV
                     ..  ..    . |...| ..|| ......|... || |..| .||.     |..|  .|. |     . ..|.... ..
..................lkqeaeaqqe..elkdyatTlllav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyane....ttfltsedaeeel

hethpgaahftgdgylapldptlaqyelqltrslghrllkragviadpevRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNA
                                                  | ..... .. ... ..||. |.|.  . . ..|. 
..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae

PP2Cc_SM00332 133-437 1.1e-26 86.8 In-house 22-273 (274) alignment
Range on Protein: 133-437
Range on HMM: 22-273/274.0
KLNQDVPFCASFKQNGHRIAIAAVFDGHGllGEIAAAMARDTMT-ALQPTFAWDSL--LTQPEQGMREIFAQLDAAIVAAHDAPPAQYtyigqsgsldfr
| ..|. ..    .. .. .. .||||||  |. .| .... .. ||. .  ...     ..|. ... | ..| .|... .    .             
ksmeDahvvvvdlveeedwlffgvfDGhg..Gsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen............

leahaipeldppsgyvctsrdgvpprpIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQaghedrdgysVEALSVQHTARSKAEQARVHETHPgaah
                            . |.|||||....|. ..| |.||  |..   ..          . .|||.|..  . | .|... ..    
...........................alsGstavvallkked.lyvanvGDSravlcrngk..........avqlsvdhkpedederkRikkagg....

ftgdgylaPLDPTLAQYELQLTRSLGHRLLKR------AGVIADPEVRSQTWpVGEVHGVVACSDGITDELSGLDVLDRVLNAG------TALEASEVLC
               .  |...|..| . ||.       ...|.|.|   |    |   .. .|||..| ||  .| | | .         . ||.| |.
........vvekgrvngglavsrafGdhflkknkklkepyitaepdvkvvtl.tsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelld

QDAQDYcmdETCIDDATAVV
. |...   ... |. |.||
eeairr...ggseDniTvvv

PP2C_SIG_SM00331 143-437 1.9e-07 23.8 In-house 23-214 (217) alignment
Range on Protein: 143-437
Range on HMM: 23-214/217.0
SFKQNGHRIAIaAVFDGHGlLGEIAAAMARDTMTALQPTFAWDsllTQPEQGMREIFAQLDAAivaahdappaqytyigqsgsldfrleahaipeldpps
 .| |..|... .|.||.|  |  |||... . |||.  .  .   . ..| ....   ...                                      
vvklnegrlll.vvaDgmG.kGlaAaaassqlrtalrellseg...eelsqalkrlnraiyee.....................................

gyvctsrdgvpPRPIDFGCTAVVAVV-VDETHVVVGNAGDAAAFVLLrD-QAGHE--Drdgysvealsvqhtarskaeqarvhethpgaahftgdgylap
               . ..|...|..   . .. . ||||   ..|  | .  ..  |                                          
...........keekgmfaTlllalydfssgklsyanaGdsrpyllr.dgklveilkd..........................................

ldptlaqyelqltrslghRLLKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELS----GLDVLDRVLNAGTALEASEVLCQDAQDYCM---DETCID
                   . . .|.. ...|....  . .   .. ..||.|.  |    . . | ..| . .  || |.  .. .. .    ..   |
..................vegaplGlepevsvdirelelekgdllllytDGltearsekgfaeerleeiledlvdseaqelaqkiveellelakgsngeD

DATAVV
|.| ||
diTvvv

PPM_PTC7_SpoIIE 146-420 5.3e-14 45.6 In-house 29-221 (230) alignment
Range on Protein: 146-420
Range on HMM: 29-221/230.0
QNGHRIAIAAVFDGHGLLGEIAAAMARDTMTALQpTFAWDslltQPEQGMREIFAQLDAAIVAAhdappaqytyigqsgsldfrleahaipeldppsgyv
  |.  .. ...||||.    |....|... .|  .  ..    .||. .|.....|.|..  .                                    
sggrlalvvgdvdGhGgraalamgllrtalrela.fagle....kpeeilrrlnlalaadlede....................................

ctsrdgvpprPIDFGCTAVVAVVVDET-HVVVGNAGDAAAFVLLRdQAGhedrdgysvealsvqhtarskaeqarvhethpgAAHFTgDGYLAP-L--DP
          |.. |.|||||..  .| .. | ||||  ....   ..|                                  .. . ..  .| |  .|
..........psssgaTavvalidpstgklyvanaGdsppllvrd.dgg.................................ereri.vagglpslGilp

TLAQYELQLTRSLGHRLLKR--AGVIADPEvRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALeASEVLCQDA
.    .|..... | .||.     | | |.  |...  |. . ....|||..| ||  ...| |..   .. |.| | .|.
grvfgvlavslapGdllllytDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp.aaeglleDD

subfamily_PPM1A_pd Subfamily PPM1A 151-441 2.2e-15 49.8 In-house 42-281 (282) alignment
Range on Protein: 151-441
Range on HMM: 42-281/282.0
IAIAAVFDGHGllG-EIAAAMARDTMTALQPTFAWDSlLTQPEQGMREIFAQLDAAIVAAHDAPPAQYTYIG---QSgsldfrleahaipeldppsgyvc
 .  ||||||.  | |.|  ...  ....  . .. .  .. ..  .|.  .|  ...|...|  .. |      .|                       
wsfFavfDGHa..Gsevakyvkkhllenileeeelke.aaleasekdevkealrqgfLaldeairelstdlktadks.......................

tsrdgvpprpidfGCTAVVAvVVDETHVVVGNAGDAAAfVLLRDQaghedrdgySVEALSVQHTARSKAEQARVHETHPGAAHFTGDGYlapldptlaqy
             |.|||.. .| |.|... |.||. | || |..         ... |.  | . .. |. |...          .|            
.............GsTavtv.lvsekhliianlGDsRa.vlcrng.........kaaflteDHkpsrpkEkkRieqAGGsvvvsRvnGa...........

eLQLTRSLGHRLLKR--------AGVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDETCIDDATAVVA
 | ..|.||   .|.          |.|.|||.|.     . . |.|| ||| | ||  .|.. | .  .. .  | ....  |... .   |  ...| 
.LAvsRalGDyeykeeeekkaeeqlvsaepevtsierseeddflvlac.DGiwDvlsdeevvelvrkrlevadeleevakalvdkalekgsrDNlsvlvv

LFP
||.
lfa

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 253-437 1.5e-09 30.6 In-house 89-250 (255) alignment
Range on Protein: 253-437
Range on HMM: 89-250/255.0
PPRPIDFGCTAVVAVVVDEtHVVVGNAGDAAAFVLlrdqagheDRDGYSvEALSVQHTARSKAEQARVHEThpGAAHFTGdgylapLDPTLAQYELQLTR
 .||.  |.||........ .|.. | ||. . .         ..|| . . ||. |    . |. |..|   |    ..         .     | ..|
serpkfiGttaasvliied.kvyianvGdsrvvlc........qkdgta.krlsldhkPseeseekrisel..GGtvvst......vvtsrvnGtlavsr

SLGHRLLKrAGVIADPEVR-SQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEASEVLcqdaQDYCMDETCIDDATAVV
.||   |.   |..||..  | .    . . ..|| ||| |..|  .  . |..   . .|.| |    .|.       |. . .|
alGdsfle.PfvvpdPdlsqsleiskkdkflilac.dGiwdlisdeeaveivagisdpekaaekl....rdlayssGstdnisviv

PP2C Protein phosphatase 2C 256-423 3e-19 62.6 Pfam-A 97-249 (255) alignment
Range on Protein: 256-423
Range on HMM: 97-249/255.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHftgDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  .|.|           .|...|.. .. | .|. | .    .    |..           |...|.||
psksGstavvalirgkk.lyvAnvGDSravLcrkdnak.........keltedHkpsdedEreRIeeaggsvsn...ngrvngs........LavsRalG

HRLLKR---AGVIADPEVRSQTWPVGeVHGVVACSDGITDELSGLDVLDRVLNAGTA----LEASEVLCQDAQDY
   ||.   . |.|.|.|.| .      . .. .|||..| ||  .. | | .  ..     ||.| |...|...
dfelkpkeeqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiar

PP2C Protein phosphatase 2C 256-423 3e-19 62.6 In-house 97-249 (255) alignment
Range on Protein: 256-423
Range on HMM: 97-249/255.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHftgDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  .|.|           .|...|.. .. | .|. | .    .    |..           |...|.||
psksGstavvalirgkk.lyvAnvGDSravLcrkdnak.........keltedHkpsdedEreRIeeaggsvsn...ngrvngs........LavsRalG

HRLLKR---AGVIADPEVRSQTWPVGeVHGVVACSDGITDELSGLDVLDRVLNAGTA----LEASEVLCQDAQDY
   ||.   . |.|.|.|.| .      . .. .|||..| ||  .. | | .  ..     ||.| |...|...
dfelkpkeeqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiar

PPM_PTC7 256-423 1.4e-18 60.2 In-house 98-253 (259) alignment
Range on Protein: 256-423
Range on HMM: 98-253/259.0
PIDFGCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGhedrdgysvEALSVQHTARSKAEQARVHETHPGAAHFtGDGYLAPLdptlaqyeLQLTRSLG
|.. |.|||||...... . | |.||. | .  ...|           .|...|.. .. | .|. . .    .  |.|..           |...|..|
pstsGstAvvalitgsk.lyvAnvGDSravLcrsgnav.........kqltedHkpsnedEreRiegaggsvsnv.gngrvngv........lavsRafG

HRLLKR-----AGVIADPEVRsQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGT---ALEASEVLCQDAQDY
   ||.       |.|.|..  .|    | . .. .|||..| .|  .. | | .      . ||.| |...|...
dfelkpketeeqlvsaePdis.stkideedefliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiar

subfamily_TAB1_pd Subfamily TAB1 257-397 6.9e-07 21.4 In-house 127-263 (333) alignment
Range on Protein: 257-397
Range on HMM: 127-263/333.0
IDFGCTAVVAVVVDEtHVVVGNAGDAAAFVLLRDQaghedrdGYSVEALSVQHTARSKAEQARVHETHPGAAHFTGDGYLAPLDPTLAQYELQLTRSLG-
|  | |||||... . .. | |.||. | .. | .          |. |||.||   . |  |...    . .    . |.  ..| .  .....     
isgGttAvvalifnn.kLyVaNvGdsrAllvkrke.......sekvkqLsvdHttdNedEllRlkdLGldieqikrnkrlgskentRsiGdykvkkgykd

HRLLKRA---GVIADPEVRsQTWPVGEVHG-VVACSDGITDELSGL
  .|..|    |||.|..   ..|. .. . .|  |||.   |  .
vdilssakgePviaePdiq.gaypiddityflvlmSdGvyktLeev

subfamily_PPM1G_pd Subfamily PPM1G 258-434 8e-07 21.4 In-house 295-458 (473) alignment
Range on Protein: 258-434
Range on HMM: 295-458/473.0
DFGCTAVVAVVvDETHVVVGNAGDAAAfVLLRDqaghedrdGYSVEaLSVQHTARSKAEQARVHEThPGaaHFTGDGYLA---PLDPTLAQYELQLTRSL
| |.|||||..  | ...| ||||. . || |.        |  .. ||. |    . |..|...   |  . . || .     |   |  .  . ...|
dsGttAvvaLl.kekklivAnaGDsRc.vlsrn........GkAld.lslDHkPeDevEleRiekA.GG..kvdedgRvnGGLnlsRAlGDhaYkkneeL

GHRLLKragVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLNAGTALEA--SEVLCQDAQDYCMDETCIDDAT
...      . | |... .|    .   |.|| ||| . ..  .|.| | .  .  |    . ....  | |. .   .| |
plkeqm...isAlPDikvltlteedeFlvlAc.DGiWnvmesqevvdfvraklkkgeesvlseiveeLlDaclapdtsgDGt

subfamily_PPM1K_pd Subfamily PPM1K 259-439 6.1e-15 48.1 In-house 98-257 (263) alignment
Range on Protein: 259-439
Range on HMM: 98-257/263.0
FGCTAVVAVVVDETHVVVGNAGDAAAfVLLRDqaghedrdGYsVEALSVQHTARSKAEQARVHETHpGAAHFTGdgylapLDPTLAQYELQLTRSLGHRL
 | || |... | |..|. . ||. | .| |.        |   . |.  |.   . |. |....  |  ...       |.  |    | .|||||   
sGttatvsllrdGtelvlaslGdsra.ilcrn........Gk.akkltrdhdPeleeekerikaag.Gsvewns......lgkplvngrlamtrslGdld

LKRAGVIADPEVRSQTWPVGEVHGVVACSDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDetciDDATAVVAL
||| ||||.|| .|     ..   .| ..|||.. ..  .. | |       ||...|.. | .|  .    |.|||||  
lkryGviatPetkslkvdhaadsflvlitdgisfvvnsqelcdlvrlchdpeeaahalteqalqygse....dnatavvvp

subfamily_PPM1G2_pd Subfamily PPM1G2 259-429 1.9e-07 23.3 In-house 115-269 (287) alignment
Range on Protein: 259-429
Range on HMM: 115-269/287.0
FGCTAVVAVVVDEThVVVGNAGDAAAFVLlrdqaghedRDGYsVEALSVQHTARSKAEQARVHETHpGAAHFT-GDGYLApLDPTLAQYELQLTRSlghR
 |.||||... .|  ..|.||||. | .           .|  |.|||. |  ....|. |. ..  |  ..    | || |   |. .| . . .    
aGstavvvlikeek.lyvanaGDsravls.........skgn.vkalsfDhkPqeesekkriiaag.GfvelnrvngnLa.lsralgDfefkknvk...k

LLKRAGVIADPEVRSQTWPvGEVHGVV-ACsDGITDELSGLDVLDRVLNAGTALEASEVLCQDAQDYCMDETC
  . . | | |.|  .     .   .| || ||| | |.  .|.| | .  .   . . ....  | |. ...
kpeeqivtavPDvlvkkld.eddeflvLaC.DGiWDvltnkevvdlvrerlvsgakldeiieelldkclapds

subfamily_ILKAP_pd Subfamily ILKAP 260-405 1.6e-10 33.6 In-house 114-241 (293) alignment
Range on Protein: 260-405
Range on HMM: 114-241/293.0
GCTAVVAVVVDEThVVVGNAGDAAAFVLLRDQAGHEdrdgYSVEALSVQHTARSKAEQARVHEthpgAAHFTGDGYLAPLdptlaqyeLQLTRSLGHRLL
|.||.| .|.|.. . |.| ||. |... ....|..    ... .|...||. .. |. |..     |  .  || .  .        |. .||.|    
Gstatvvlvldnv.lyvanlGdskavlvrkkeegdk....iasvvLtkdhtpvkyeerkriqk....aGgvvrdgrvlGv........levsrsiGdgrf

KRAGVIADPEVRSQTWPVGEVHGVVACsDGITDELSGLDVLDRVLN
||.|||. |.|.  .    . . |.|| ||. . .|  .|.. .|.
krlGvistPdvkkceLtendlfvvlaC.dGLwkvfsadevvkfilk

subfamily_PDP_pd Subfamily PDP 260-329 6.9e-09 28.3 In-house 153-216 (398) alignment
Range on Protein: 260-329
Range on HMM: 153-216/398.0
GCTAVVAVvVDETHVVVGNAGDAAAFVLLRDQAGHedrdgYSVEALSVQHTARSKAEQARVHETHPGAAH
| .|..|. ...|.. | |.||..| .  ... |.     ... .|| ..||....|  |... |||  .
Gacallal.iegtelhvAntGDcravlgvqeeegs.....weavkLskdqtadneeEveRikkeHPgees

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 260-371 4e-08 26.1 In-house 86-197 (292) alignment
Range on Protein: 260-371
Range on HMM: 86-197/292.0
GCTAVVAVVVDETHVVVGNAGDAAAfVLLRDQAGHEdrdgYSVEALSVQHTARSKAEQARVHETHPGAA--HFTGDGYLAPLDP---TLAQYELQLTRSL
. ..| |.| |.  ... | ||. | .| |  .| .    | .  || .|      |.||.  .       .  | |.  .         . .| |.|.|
ttavvcarvrddralilanvGdsra.llgrclggsd....yeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsral

GHRLLKRAGVIADPEVR
|   |. |||.|.||..
GdfhlfeaGvvaePelq