Gene MbrePPM-Un-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP125_AA protein Get Run
MbreP125_AA_443-735 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0034914 PP2C-like 444-717 5.1e-39 127.0 In-house 28-256 (295) alignment 
Range on Protein: 444-717
Range on HMM: 28-256/295.0
YAGNPKENQDGFLVYEGS---SALPFLAAVMDGHGvnGRKVSGFAESTLGVEILE--------SYRQNQALSEALVNGIVSTAAKLRKSTID---ARESG
  |. |.|.| .||. .        .|..| ||||  | ... .| ..|  ..||        ..     . |||.......  .|.. ...    . ||
dqGrrksneDavlvvlnllslledlllfgvfDGhg..GhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsG

TTAVVCARtpDGRQLIVANVGDSRCVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRgwgfqgparvwrrrqqeGGLALSRSVGDFHL
|||||.     |..|.||||||||.|| |  .|   ....|..||||... ||.||..|||.|   ||                  |.||..|..|||.|
tTavvali..rgnklyvanvGDSravllr..ng...elvqltvdhkpvnelererilsaggavshgrvn.................gvlavtRalGdfdl

F--------EAGVVAEPELQIHAGRQ--YlgrgpglwtrssiarhiayqhpltsdvplgldrklektldsqdHFIVLGSDGVFDHLSNAQVILFLAKY
.        | .|.|||.....      .                                           .|..|.|||..|.||| ... .....
klllslllleplvsaePdvtvleltledd...........................................dfllLasDGlwdvlsneeivdivrsl
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 445-736 4.1e-181 594.0 In-house 1-292 (292) alignment 
Range on Protein: 445-736
Range on HMM: 1-292/292.0
AGNPKENQDGFLVYEGSSALPFLAAVMDGHGVNGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKLRKSTIDARESGTTAVVCARTPDGRQL
|.|.|||||.||..|||.||.|||||.|||||||.||...||.||.||.||..||.|.|||||...|...||||.|.|||||||.||||||||..|.|.|
aankkenqdrfllvegsealtflaavldGhGvnGdkvaqlaedtlevelleltrqlqelsealllrildiaakldkltidaresattavvcarvrddral

IVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWGFQGPARVWRRRQQEGGLALSRSVGDFHLFEAGVVAEPELQIHA
|.|||||||..||||||||.|..|||||||||.||.||.||.||||.|||||||||||.|.|||||||||||.|||||..||||||||||||||||||||
ilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdfhlfeaGvvaePelqiha

GRQYLGRGPGLWTRSSIARHIAYQHPLTSDVPLGLDRKLEKTLDSQDHFIVLGSDGVFDHLSNAQVILFLAKYQEGADFVITSNSLECHLSS
|||||||||||||||||||||||||||||||||||||||||.|||.|.|.||.||||.|.|.||.|.|.|||.||.||.|||...||..||.
grqylgrgpglwtrssiarhiayqhpltsdvplgldrklekeldsddaflvlasdGvldvllnaevvlllaksqeaadkvitelaleyglsd
subfamily_PPM1K_pd Subfamily PPM1K 445-641 4.8e-22 71.3 In-house 12-193 (263) alignment 
Range on Protein: 445-641
Range on HMM: 12-193/263.0
AGNPKENQDGFLVYEGSSALPFLaAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKLRK------STIDARESGTTAVVCArT
 |  .||.| . . | .  | .. || |||.  |     |. . |   . . . ... | . |.|       ||..      .  .  .||||| |.   
iGkraenedriklkeldpellyv.avfdGha..GsaaadfvhdklekilkrllekekdleivlknafeeldkklkrylefsvaeaellssGttatvsl.l

PDGRQLIVANVGDSRCVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEptrvrgWGFQGPARVwrrrqqEGGLALSRSVGDFHLFEAGVVAEP
 || .|..|..|||| .| |   |   ..  |.|||.|.   |..||..||| ||      |   |  .|      .| ||..||.||. | . ||.|.|
rdGtelvlaslGdsrailcr..nG...kakkltrdhdPeleeekerikaagGsve......wnslgkplv......ngrlamtrslGdldlkryGviatP

ELQ
| .
etk
PP2C_2 Protein phosphatase 2C 445-557 8.3e-08 24.8 Pfam-A 6-124 (212) alignment 
Range on Protein: 445-557
Range on HMM: 6-124/212.0
AGNPKENQDGFLvYEGSSALPFLaAVMDGHGVN--GRKVSGFAESTLgVEILESYRQNQA-L-SEALVNGIVSTAAKL-------RKSTIDARESGTTAV
. . | .|| .. .  .|.  .| || ||.|    ..| . .| ... .| ||.. ....   .|||.. |.. . ..        ..  .... .|| .
rrkgkpcqDala.ireasdgwll.aVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTll

VCARTPDGrqLIVANVGDSRCVLG
....||..  ......||...|. 
lavitpge..ivffqiGDgaivvr
PP2C_2 Protein phosphatase 2C 445-557 8.3e-08 24.8 In-house 6-124 (212) alignment 
Range on Protein: 445-557
Range on HMM: 6-124/212.0
AGNPKENQDGFLvYEGSSALPFLaAVMDGHGVN--GRKVSGFAESTLgVEILESYRQNQA-L-SEALVNGIVSTAAKL-------RKSTIDARESGTTAV
. . | .|| .. .  .|.  .| || ||.|    ..| . .| ... .| ||.. ....   .|||.. |.. . ..        ..  .... .|| .
rrkgkpcqDala.ireasdgwll.aVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTll

VCARTPDGrqLIVANVGDSRCVLG
....||..  ......||...|. 
lavitpge..ivffqiGDgaivvr
PP2Cc_SM00332 446-735 2e-38 125.4 In-house 19-244 (274) alignment 
Range on Protein: 446-735
Range on HMM: 19-244/274.0
GNPKENQDGFLVYEG--SSALPFLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA-----LSEALVNGIVSTAAKLRKSTIDAR----ESGTTAVV
|..|...| . |.    ...   . .| ||||  | .|. |. . |   . |.  . .        ||| ....||  .....    .     ||.||||
gwrksmeDahvvvvdlveeedwlffgvfDGhg..GsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenalsGstavv

CARTPDGrqLIVANVGDSRCVLGRCLGgsryqPIPLSRDHKPSDPGERQRIQRAGGyveptrvrgwgfqgparVWRRRQQEGGLALSRSVGDFHLF----
.  . .   |.||||||||.||.|         ..||.||||.|. ||.||..|||                 | ....  ||||.||. ||..|     
allkked..lyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkagg.................vvekgrvngglavsrafGdhflkknkk

--EAGVVAEPELQIHAGrqylgrgpglwtrssiarhiayqhpltsdvplgldrklektlDSQDHFIVLGSDGVFDHLSNAQVILFLAKYQEGAdfvitsn
  | ...|||. ....                                           .|.| |..| |||..|.||| .|. .. |  .         
lkepyitaepdvkvvtl..........................................tsedeflilaSDGlwdvlsnqevvdivrkllakg.......

slechlS
      .
......k
0049733 PP2C-like 446-716 1.3e-28 93.0 In-house 12-203 (235) alignment 
Range on Protein: 446-716
Range on HMM: 12-203/235.0
GN-PKENQDGFLVyegssaLPFLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA--LSEALVNGIVSTAAKLRKSTID---ARESGTTAVVCARTp
|.  |.|.| .||        .|.|| ||||  |  ....| ..|   .|| ...     | |||.. .  . . |.. ...    . .||||||.  . 
grvrkvneDavlv......glllfavaDGhg..ghaagevasellvetllelllelllldleealrkaflaaneallelalaspelagmgtTavvalld.

dGRQLIVANVGDSRCVLGRclggsRYQPIPLSRDHKPSDPGERQRIQRAGGYVeptrvrgwgfqgparvwrrrQQEGGLALSRSVGDFHLFeagvvaepe
 |..|.||||||||..| |     . . ..|..||.|... |||||..|||.|                       |.|||.|..||..|          
.ggklyvanvGDsrayllr.....dgklvqltedhspvnelerqriitaggav....................rvpgrlaltralGdlllk.........

lqihagrqylgrgpglwtrssiarhiayqhpltsdvplglDRKLEKTLDSQDhFIVLGSDGVFDHLSNAQVILFLAK
                                            . .|...| |..| |||..|.||. ... .|..
........................................pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs
PP2C_SIG_SM00331 453-717 8e-09 28.4 In-house 19-181 (217) alignment 
Range on Protein: 453-717
Range on HMM: 19-181/217.0
DGFLVYEGSSAlPFLAAVMDGHG--VNGRKVSGFAESTLGVEILESyrqnqalsEALVNGIVSTAA----KlrkstIDARESGTTAVVCARTPDGRQLIV
| . |.. .    .|..| ||.|  ...  .|. . . |  .. |         |.|.. .  .      .      . .....|....   . ...| .
Dyydvvklneg.rlllvvaDgmGkGlaAaaassqlrtalrellseg........eelsqalkrlnraiyee.....keekgmfaTlllalydfssgklsy

ANVGDSRCVLGRclGGSRYQPIPLsrdhkpsdpgerqriqraggyveptrvrgwgfqgparvwrrrqqegglalsrsvgdfhlfeagvvaepelqihagr
||.||||..| |   | . ...                                                                              
anaGdsrpyllr..dgklveilkd............................................................................

qylgrgpglwtrssiarhiayqhplTSDVPLGLDRKLE----KTLDSQDHFIVLGSDGVFDHL-----SNAQVILFLAKY
                         ..  ||||  ...    ..  ... ...| .||...        .......|...
.........................vegaplGlepevsvdirelelekgdllllytDGltearsekgfaeerleeiledl
PPM_PTC7_SpoIIE 463-713 1e-17 57.7 In-house 32-204 (230) alignment 
Range on Protein: 463-713
Range on HMM: 32-204/230.0
ALPFLAAVMDGHGVNGRKVSGFAESTLGVEILESYRqnqALSEALVNGIVSTAAKLRKStidARESGTTAVVCARTPDGRQLIVANVGDSRCVLGRClGG
 | .. .. ||||.   ...| . ..|  .. .. .    ..|.| ..    ||.|...     .||.||||.  .|. ..| |||.|||...| |  .|
rlalvvgdvdGhGgraalamgllrtalrelafagle...kpeeilrrlnlalaadlede...psssgaTavvalidpstgklyvanaGdsppllvrd.dg

SryqpiplsrdhkpsdpgERQRIqRAGGYVE----PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEagvvaepelqihagrqylgrgpglwtr
                  || ||  ||| ..    |.|| |                  ||.|.. ||. |.                            
g.................ereri.vagglpslGilpgrvfgv.................lavslapGdlllly...........................

ssiarhiayqhpltSD-VPLGLDRKLEKTLDSQDHFIVLGSDGVFDHLSNAQVILF
              .| |    ..  .. |.. |.|..|.|||..|.||..... .
..............tDGvveaepdtsdgelfgkdeflilasdglwdvlspqelvdl
PP2C Protein phosphatase 2C 466-643 2.1e-32 105.7 Pfam-A 35-196 (255) alignment 
Range on Protein: 466-643
Range on HMM: 35-196/255.0
FLAAVMDGHGvnGRKVSGFAESTLGvEILESYRQNQAL---SEALVNGIVS-TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
 . ||.||||  ||... .|...|  |||.. .. . |   ..|| ... . |. .|..   .|     ||.||||.  ...   |.||||||||.||.|
affavfdghg..greaakyarehle.eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkk..lyvAnvGDSravLcr

CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE-PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE---AGVVAEPELQIH
  .        |..||||||. ||.||..|||.|.  .||.|                  ||.||..|||.|..   . |.|||... .
kdnak....keltedHkpsdedEreRIeeaggsvsnngrvngs.................LavsRalGdfelkpkeeqlvsaePdvtsv
PP2C Protein phosphatase 2C 466-643 2.1e-32 105.7 In-house 35-196 (255) alignment 
Range on Protein: 466-643
Range on HMM: 35-196/255.0
FLAAVMDGHGvnGRKVSGFAESTLGvEILESYRQNQAL---SEALVNGIVS-TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
 . ||.||||  ||... .|...|  |||.. .. . |   ..|| ... . |. .|..   .|     ||.||||.  ...   |.||||||||.||.|
affavfdghg..greaakyarehle.eilkeqksflelekvekalrksfladtdeelksskant.epsksGstavvalirgkk..lyvAnvGDSravLcr

CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE-PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE---AGVVAEPELQIH
  .        |..||||||. ||.||..|||.|.  .||.|                  ||.||..|||.|..   . |.|||... .
kdnak....keltedHkpsdedEreRIeeaggsvsnngrvngs.................LavsRalGdfelkpkeeqlvsaePdvtsv
PPM_PTC7 466-643 5.2e-32 104.3 In-house 35-201 (259) alignment 
Range on Protein: 466-643
Range on HMM: 35-201/259.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA--LSEALVNGIVS--TAAKLRK---STiDARESGTTAVVCARTPDGrqLIVANVGDSRCVLGR
 . || ||||  ||... .|...|   . |... ..   |..|| ... .  |. .|..   .|     ||.||||.. |..   |.||||||||.||.|
affavfdghg..greaakyarehleeilkerksfeeleklekalrksflaldtdeelksseant.epstsGstAvvalitgsk..lyvAnvGDSravLcr

CLGGSryqpIPLSRDHKPSDPGERQRIQRAGGYVE---PTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFE-----AGVVAEPELQIH
  .       .|..|||||.. ||.||..|||.|.    .||.|                  ||.||..|||.|..       |.|||. . .
sgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngv.................lavsRafGdfelkpketeeqlvsaePdisst
subfamily_PPM1A_pd Subfamily PPM1A 466-637 2.8e-26 85.5 In-house 43-200 (282) alignment 
Range on Protein: 466-637
Range on HMM: 43-200/282.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILES--Y-------RQNQALSEALVNGIVSTAAKLRKSTIDAR---ESGTTAVVCARTpdGRQLIVANVGDSR
 . ||.|||.  |..|. .....|  .|||.  .       .......||| .|....  ..|... |..   .||.|||..  .   ..||.||.||||
sfFavfDGHa..GsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlktadksGsTavtvlvs..ekhliianlGDsR

CVLGRclGGsryQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEAGVVAE
 || |  .|   . . |..|||||.| |..||. ||| |   || |                  ||.||..||... |.    .
avlcr..ng...kaaflteDHkpsrpkEkkRieqAGGsvvvsRvnGa.................LAvsRalGDyeykeeeekka
subfamily_PPM1L_pd Subfamily PPM1L 466-639 7.8e-21 67.5 In-house 36-198 (269) alignment 
Range on Protein: 466-639
Range on HMM: 36-198/269.0
FLAAVMDGHGvnGRKVSGFAESTLGVEILESY------RQNQA---LSEALVNGIVSTAAKLR-KSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCV
 . ||.||||  |   . ||.. |  .|..        ..|.     |. |.. |.|   ||  | .    ..||||..   .  ...|||||||||| |
sffavfdGhG..GefaaefakdvlvkaiknklieldadkentepinfsklltdeilsvdekllekakraediaGttalialvq..esdlivanvGdsrGv

LGRCLGgsryQPIPLSRDHKPSDPGERQRIQRAGGYVeptrvrgwGFQGparVWRRrqqEGGLALSRSVGDFHLFEAGV-VAEPE
|    |    . |||| |||| .. ||.||..|||..         |.|   |||    .| || ||..||. | .  . .|.|.
lydkrG....kaiplsfdhkpqqvkerkrikkaGGfi........afrG...vwrv...aGvlatsralGdyplkdknlviadpd
subfamily_PPM1G2_pd Subfamily PPM1G2 467-715 1.8e-29 95.6 In-house 54-244 (287) alignment 
Range on Protein: 467-715
Range on HMM: 54-244/287.0
LAAVMDGHGvnGRKVSGFAESTLGVEILE--SYRqNQALSEALVNGIVSTAAKLRKS-TIDARESGTTAVVCARTPDGrqLIVANVGDSRCVLgrCLGGS
| ||.||||  |.||. .| . |   | .  |.. ..||...| .....|  .|.|  ...  ..|.||||   . .   |.|||.||||.||  .  |.
lfavfDGhG..Gakvakyagkklikkiakkksfk.egaleqilkdafletDeellkdeklkdesaGstavvvlikeek..lyvanaGDsravl..sskgn

ryqPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVrgwgfqgparvwrrrqqEGGLALSRSVGDFHlFEAGVVaepelqihagrqylgrgpglwtrssiar
      ||.||||.. .|..||. |||.||  ||                  | |||||..|||. |  .|                             
...vkalsfDhkPqeesekkriiaagGfvelnrv.................ngnLalsralgDfe.fkknvk............................

hiayQHPLTSDVPLGLDRKLEKtLDSQDHFIVLGSDGVFDHLSNAQVILFLA
    ..|    |    |  ..| ||..| |.||  ||..| |.|..|. .. 
....kkpeeqivtavPDvlvkk.ldeddeflvLaCDGiWDvltnkevvdlvr
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 468-641 1.4e-17 56.9 In-house 39-188 (255) alignment 
Range on Protein: 468-641
Range on HMM: 39-188/255.0
AAVMDGHGvnGRKVSGFAESTLGVEILESYRQNQA-LSEALVNGIVSTAAKLRKSTidaRESGTTAVVCARTPDgrQLIVANVGDSRCVLGRCLGGSRYq
 |..||||  ||. . ||  .|   . |    |.|   ..| .   ..  .. . .   .  ||||..   . |  . ..||||||| ||..  | ..  
yalfdGhg..GraaakfaseelykilaelldlnnanPvkslkkaykeistqiserp...kfiGttaasvliied..kvyianvGdsrvvlcqkdgtakr.

pipLSRDHKPSDPGERQRIQRAGGYVEPTrvrgwgfqgparvWRRRQQEGGLALSRSVGDFHLfEAGVVAEPELQ
   || |||||.. |..||...|| |  |                 . .| ||.||..|| .| |  ||..|.|.
...lsldhkPseeseekriselGGtvvst.............vvtsrvnGtlavsralGdsfl.ePfvvpdPdls
subfamily_PPM1D_pd Subfamily PPM1D 468-631 2.6e-15 49.3 In-house 38-214 (309) alignment 
Range on Protein: 468-631
Range on HMM: 38-214/309.0
AAVMDGHGvnGRKVSGFAESTLGVEILES----YRQNQALSEALVNGIVSTAAKLRKSTI--------DARESGTTAVVCARTpdGRQLIVANVGDSRCV
 ||.||||  |.. . || . |  .| .      ...... ||. .. ..|  ...|.          .   .|||| |   .  ...| ||.||||. |
vavfDGHG..GkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkleeWpktksgllstaGttasvviir..reklyvahvGDsaiv

LGRCLG-GSRYQPIPLSRDHKPSDPGERQRIQRAGGYVEPT----RVRgWGF-QGPARVWRRRQQEGGLALSRSVGDFHLFE
||      .. .. .| .||||..| |..||...|| |       ||  |   .   .  . ...   ||..||.||.  ..
lgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvv.WkRprlehngptvideiPFLavaRslGDlWsyn
subfamily_KAPP-like_pd Subfamily KAPP-like 468-596 3.1e-09 29.3 In-house 37-165 (266) alignment 
Range on Protein: 468-596
Range on HMM: 37-165/266.0
AAVMDGHGVNGRKVSgfAESTLGVEILESYRQ---------NQALSEALVNGIVSTAAKLRKStidaRESGTTAVVCARTPDGRQLI--VANVGDSRCVL
 ||.|||  .|  ..  |.  .  |. .  ..         .   |. | | . .  |||..        |.|| ..    ||.|    |||||||   |
favfdGhaGkGaada..akklfpkelekllkstkqddGGdniydqskllenafkevdaklkdf....eyeGatatlalvwsdGqqrylqvanvGdssafl

GRclGgsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTR
 |  |    . . || |||  || |.|||.  |  .  ..
sr..G...neslelskdhkakdpeekqrikddGitlsdnq
subfamily_PPM1E_pd Subfamily PPM1E 469-640 6.9e-19 61.0 In-house 44-192 (265) alignment 
Range on Protein: 469-640
Range on HMM: 44-192/265.0
AVMDGHGvnGRKVSGFAESTLGVEILESYRQNQALSEALVNGIVSTAAKL-RKSTIDARESGTTAVVCARTpdGRQLIVANVGDSRCVLGRclggsRYQP
||.||||  | . . .| . |   . .  ....   ||| ...  |  .. .|.. .. .||.||||.. .  ..|| || .|||. .| |       . 
avfDGHg..GveaakyaaahlhellvrqeklkedpaealkeafkltDerflqkaereklksGstavvvlie..kdqlyvaWlGDsqallvr.....kgea

IPLSRDHKPSDPGERQRIQRAGGYVeptrVrgWgFqGparVWRRrqqEGGLALSRSVGDFHLfEAGVVAEPEL
. | . |||... |..||. ||| |    |  . . |   .||     | |..||..|| .| .. |..|...
vqlmkpHkPeredEkkRieeagGlv....v..v.i.g...awRv...nGvLsvsRaiGDvkl.kpyvsgeadv
subfamily_ILKAP_pd Subfamily ILKAP 469-640 1.6e-17 56.6 In-house 47-207 (293) alignment 
Range on Protein: 469-640
Range on HMM: 47-207/293.0
AVMDGHGvnGRKVSGFAESTLGVEILESYRQN------QALSEALVNGIVSTAAKLRKSTIDA---RESGTTAVVCARTPDgrQLIVANVGDSRCVLGRC
|| |||.  |.. | || ..|  .||| . ..      . .  .||.    |  .. |    |      |.||.|.    .   | |||.|||..|| |.
avfdGha..GsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLklaskakPvWkdGstatvvlvldn..vlyvanlGdskavlvrk

LGGSR-YQPIPLSRDHKPSDPGERQRIQRAGGYVEPTRVRGWgfqgparvwrrrqqeggLALSRSVGDFHLFEAGVVAEPEL
   .. .. ..|..||.| .  ||.|||.|||.|.  || |                  |  |||.|| .  ..||.. |..
keegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdgrvlGv.................levsrsiGdgrfkrlGvistPdv
subfamily_PPM1H_pd Subfamily PPM1H 495-588 8.9e-07 21.0 In-house 123-213 (404) alignment 
Range on Protein: 495-588
Range on HMM: 123-213/404.0
ESYRQNQALSEALVNGIVSTAAK-----LRKSTIDARESGTTAVVCARTPDGrQLIVANVGDSRCVLGRCLGGsryqpIPLSRDHKPSdpGERQRIQRA
| |....  .| || | . .| .     ...   . | .|  ... | . .| .| ||| |||| .| |.        ||||.|. |    ||||.|. 
eiyeekeiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllg.klYvanaGDsRailvrkdei.....iplsadftPe..teRqRlqel
subfamily_PDP_pd Subfamily PDP 515-588 6.8e-11 34.9 In-house 139-210 (398) alignment 
Range on Protein: 515-588
Range on HMM: 139-210/398.0
AAKLRKSTIDARESGTTAVVCarTPDGRQLIVANVGDSRCVLGRCLGGSRYQPIPLSRDHKPSDPGERQRIQRA
  |  ......  ||..|..     .|..| |||.||.|.|||.  . . .. ..||.|.  . . | .||...
kekslreallvalsGacalla..liegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikke
subfamily_PPM1G_pd Subfamily PPM1G 522-628 3.5e-21 68.7 In-house 290-373 (473) alignment 
Range on Protein: 522-628
Range on HMM: 290-373/473.0
TIDARESGTTAVVCARtpDGRQLIVANVGDSRCVLGRClggsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTrvrgwgfqGpaRVwrrrqqEGGLALS
    ..|||||||.     ...|||||.||||||| |       . . || |||| |. |..||..||| |.          |  ||      .||| ||
eepGedsGttAvvaLl..kekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvded........g..Rv......nGGLnls

RSVGDFH
| .||. 
RAlGDha
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 528-596 3.1e-07 22.5 In-house 104-175 (276) alignment 
Range on Protein: 528-596
Range on HMM: 104-175/276.0
SGTTAVVCARTPDG--------RQLIVANVGDSRCVLGRclGgsrYQPIPLSRDHKPSDPGERQRIQRAGGYVEPTR
 |.|| ..    ||        | | |||||||   | |  |    . . || ||| .|| |.|||.  |  .  ..
eGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsr..G...neslelskdhkatdpeekqrikddGitlsdnq
subfamily_PP2D1_pd Subfamily PP2D1 543-594 4e-06 18.8 In-house 189-235 (492) alignment 
Range on Protein: 543-594
Range on HMM: 189-235/492.0
QLIVANVGDSRCVLGRClgGSRYQpipLSRDHKPSDPGERQRIQRAGGYVEP
 | .||.|. . || |   |. ..   | |.| | .. ||.|...||. |  
vlyianaGnvqAvLcre..Gkaii...LtreHtprnkkERtRvekagsvvvk
PP2C Protein phosphatase 2C 686-714 9.7e-06 18.3 Pfam-A 197-225 (255) alignment 
Range on Protein: 686-714
Range on HMM: 197-225/255.0
TLDSQDHFIVLGSDGVFDHLSNAQVILFL
.|...|.|..|.|||..|.||. ... . 
klteedefliLasdGlwdvlsdqeavdlv
PP2C Protein phosphatase 2C 686-714 9.7e-06 18.3 In-house 197-225 (255) alignment 
Range on Protein: 686-714
Range on HMM: 197-225/255.0
TLDSQDHFIVLGSDGVFDHLSNAQVILFL
.|...|.|..|.|||..|.||. ... . 
klteedefliLasdGlwdvlsdqeavdlv
Nup35_RRM Nup53/35/40-type RNA recognition motif 912-982 7.4e-17 47.5 Pfam-A 9-94 (101) alignment 
Range on Protein: 912-982
Range on HMM: 9-94/101.0
CVTIFGFGLADLDLVMTEFERCGRILRR-------------ETKTNCNWLHVQFDDQLSAQRALSKHGMVLSARLMVGVQPC--LD
 |..|||  .. . |...|...|.||               .. |. ||...... ..||..||.. |..|   |.|||...   .
svivFGfpesianevlehFskfGeiledvqvlklgkglnpkpiptgenwvkltYksessaskAlqengtilngslivgvsyskaaa
Nup35_RRM_2 Nup53/35/40-type RNA recognition motif 913-962 7e-09 21.9 Pfam-A 4-53 (53) alignment 
Range on Protein: 913-962
Range on HMM: 4-53/53.0
VTIFGFGLADLDLVMTEFERCGRILRRETKTNCNWLHVQFDDQLSAQRAL
|...||    . ||   |. .|.| . .   . ||..... .. .|..||
VaVsGfppelielvlehFasfGeIvniyvpkevnwmylkyesekdaekAl