Gene MbrePPM-Un-2 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP127_AA protein Get Run
MbreP127_AA_10-201 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1E_pd Subfamily PPM1E 10-199 9.6e-27 86.8 In-house 83-261 (265) alignment 
Range on Protein: 10-199
Range on HMM: 83-261/265.0
SFKVTENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQinethGVNPVELNERHGTNLKSERKRILAAGGKIAPDGS--VYGVLFPSRGF
.||.|... ...|.. . ..|| . .|.....|.| .  |||.||| .      .. |.| . |  . . |.||| .||| .   |   | |||  ||  
afkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvr.....kgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRai

GDIDvkadGKPVVICTPNGAGIDdwqphrLEHSEaTWLVVASDGLWDFVVDDQVMSIVA---KNQHLDHSAIAKKLIDEARLCGSEDDITIIVVR
|| .     || |.  .. | ..      |..||  .|..|.||||| | ...|...|    .... |.| .||.|...|.  ||.|.||..|| 
GDvk....lkpyvsgeadvaeve......ldgse.eylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvf
subfamily_ILKAP_pd Subfamily ILKAP 10-168 7e-21 67.6 In-house 92-242 (293) alignment 
Range on Protein: 10-168
Range on HMM: 92-242/293.0
SFKVTENKWCERAKSANDT--AGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHG-VNPVELNERHGTNLKSERKRILAAGGKIApDGSVYGVLFPSRG
||| |.... . |..|. .   ||  | |.|    .| .| |||||.| . .|    .  | |   | .  . |||||  |||..  || | |||  || 
sfkktdeefLklaskakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvr.dgrvlGvlevsrs

FGDIDVKADGkpvVICTPNgagiddWQPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKN
 ||   |  |   ||.||.       .  .|..    ..|.| ||||. .  |.|.. . | 
iGdgrfkrlG...vistPd......vkkceLten.dlfvvlaCdGLwkvfsadevvkfilkv
0034914 PP2C-like 11-199 5.3e-37 120.3 In-house 104-289 (295) alignment 
Range on Protein: 11-199
Range on HMM: 104-289/295.0
FKVTENKWCERAKS--ANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFqineTHGvNPVELNERHGTNLKSERKRILAAGGKIAPdGSVYGVLFPSRGFG
|. .... .| | .    .. |.. ......|...|..|.|||.|.|.    ..|  .| |.. |  .  .||.|||.||| .   | |.|||  .| .|
flaadeellelallrpelagsGtTavvalirgnklyvanvGDSravll....rng.elvqltvdhkpvnelererilsaggavsh.grvngvlavtRalG

DIDVK-----ADGKPVVICTPngagidDWQPHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAK--NQHLDHSAIAKKLIDEARLCGSEDDITIIVVR
| | |        .|.|...|      | . ..|....  .|..|||||||.. ......||..  ...|| ...|..|.|.|  .|| |.||..|||
dfdlklllslllleplvsaeP......dvtvleltledddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAlargsrDNiTvvvvr
PP2Cc_SM00332 11-198 5e-34 110.9 In-house 89-274 (274) alignment 
Range on Protein: 11-198
Range on HMM: 89-274/274.0
FKVTENKWCERAKSAND---TAGSCSTAVVVKGSQVYCGNAGDSKALLFQINEthgvnPVELNERHGTNLKSERKRILAAGGKIAPDgSVYGVLFPSRGF
|. |...  | ..| ..   ..||. . ...|. ..|. |.|||.| |.. ..      |.| . | .. ..||||| .|||... .  | |.|  || |
flstdeeileeeqskelenalsGstavvallkkedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkaggvvekg.rvngglavsraf

GDIDVKA---DGKPVVICTPNGAGIDDwqphrleHSEATWLVVASDGLWDFVVDDQVMSIVAKNQ----HLDHSAIAKKLIDEARLC-GSEDDITIIVV
|| ..|.     .|.....|.   ..         ||   |..||||||| . ...| .|| |      . | ...|..|..||.   ||||.||..||
Gdhflkknkklkepyitaepdvkvvtl.......tsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeairrggseDniTvvvv
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 11-200 1.4e-23 76.5 In-house 81-253 (255) alignment 
Range on Protein: 11-200
Range on HMM: 81-253/255.0
FKVTENKWCERAksanDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgvnpVELNERHGTNLKSERKRILAAGGKIAPD---GSVYGVLFPSRGF
.| .. .  ||.       |. ...|.. . .||  | |||...| | . |     . |   |  . .||.||| ..||..  .     | | |  || .
ykeistqiserp....kfiGttaasvliiedkvyianvGdsrvvlcqkdgta....krlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsral

GDIDVkadgKPVVICTPNGAGiddwqpHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDHSaiAKKLIDEARLCGSEDDITIIVVRY
||. .    .| |.  |.  .          . .  .|..| ||.|| . |.. ..|||. .  ...  |.|| | |   ||.|.|..||...
Gdsfl....ePfvvpdPdlsq......sleiskkdkflilacdGiwdlisdeeaveivagisdpeka..aeklrdlayssGstdnisvivikl
subfamily_PPM1G2_pd Subfamily PPM1G2 11-198 1.7e-22 72.7 In-house 97-284 (287) alignment 
Range on Protein: 11-198
Range on HMM: 97-284/287.0
FKVTENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINEthgvnPVELNERHGTNLKSERKRILAAGGKIAPDgSVYGVLFPSRGFGDI
|. |...  .  | ....||| ...|..| ...|..|||||.|.| .  .        |   |  . .||.||| |||| .. .  | |.|  || .|| 
fletDeellkdeklkdesaGstavvvlikeeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkriiaagGfveln.rvngnLalsralgDf

DVKADGKpvviCTPN---GAGIDDWQPHRLEhSEATWLVVASDGLWDFVVDDQVMSIVAKN--QHLDHSAIAKKLIDEARLCGSE------DDITIIVV
  |   |     .|.      . |   ..|. ..  .||.| ||.|| . ...|. .| ..  .. . ..|...|.|..    |.      |..|...|
efkknvk....kkpeeqivtavPDvlvkkld.eddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv
0049733 PP2C-like 12-200 8.8e-30 96.9 In-house 73-233 (235) alignment 
Range on Protein: 12-200
Range on HMM: 73-233/235.0
KVTENKWCERAKS--ANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQinetHGvNPVELNERHGTNLKSERKRILAAGGKIapdgSVYGVLFPSRGFGD
. ... ..|.|..    .. |.. ..... |...|. |.||| |.|..    .| . | |.| |  .   ||.||..||| .     |.|.|  .| .||
laaneallelalaspelagmgtTavvalldggklyvanvGDsrayllr....dg.klvqltedhspvnelerqriitaggav....rvpgrlaltralGd

IDVKadgkpvvictpngagiDDWQPHRLEHSEatWLVVASDGLWDFVVDDQVMSIVAKnqhLDHSAIAKKLIDEARLCGSEDDITIIVVRY
 ..|                 |.. ..||. .  .|..|||||||.. |.........   || ...|..|...|.  |. |.||..|||.
lllk................pdvtvlelepgd..flllasDGlwdvlsdeeivdllrs...ldleeaaerlvelalarggrDNiTvvvvrl
subfamily_PPM1D_pd Subfamily PPM1D 14-100 5.4e-14 45.0 In-house 93-180 (309) alignment 
Range on Protein: 14-100
Range on HMM: 93-180/309.0
TENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINE-THGVNPVELNERHGTNLKSERKRILAAGGKIAPDGSVYGV
. ..| ....    |||.  . |.......| .. |||...| . .. .. ... || . |  .  .|..||  .||..|    |. |
kleeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRv
subfamily_PPM1L_pd Subfamily PPM1L 15-200 4.4e-25 81.4 In-house 92-266 (269) alignment 
Range on Protein: 15-200
Range on HMM: 92-266/269.0
ENKWCERAKSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINethGvNPVELNERHGTNLKSERKRILAAGGKIAPDGS--VYGVLFPSRGFGDIDV
..|  |.||.|.|.||. .   .|..|..   | |||. .|.. .   | . . |   |  .   |||||  ||| || .|.  | |||  || .||  .
dekllekakraediaGttalialvqesdlivanvGdsrGvlydkr...G.kaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdypl

KAdgKPVVICTPNGAGIDdwqphrLEHSEATWLVVASDGLWDFVVDDQVMSIVAknQHLDH-SAIAKKLIDEARLCGSEDDITIIVVRY
|   | .|| .|.   .|      |.. .  .|..|||||||   ... .  .   ..|.     || |. |.   || |.||..||..
kd..knlviadpdiltfd......lddhkpeflilasdGlwdtfsneeavrfik..erlkepdfGakslvlesfkrGsvdnitvlvvkl
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 16-94 6.6e-10 32.0 In-house 72-151 (292) alignment 
Range on Protein: 16-94
Range on HMM: 72-151/292.0
NKWCERAKSANDTAGSCSTA-VVVKGSQVYCGNAGDSKALLFQINETHGVNPVELNERHGTNLKSERKRILAAGGKIAPD
 |. .    |.  |... .  .|  . ...  | |||.|||...      ... |   |  .   ||.|||.|||.. | 
akldkltidaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrvept
subfamily_PPM1A_pd Subfamily PPM1A 19-200 8.9e-30 97.0 In-house 106-280 (282) alignment 
Range on Protein: 19-200
Range on HMM: 106-280/282.0
CERAKSAnDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINethgvNPVELNERHGTNLKSERKRILAAGGKIApDGSVYGVLFPSRGFGDIDVKAD---
 ...|.| | .|| ...|.|. ..... |.|||.|.|.. .     . . | | |  . ..|.||| .|||..   . | | |  || .|| ..| .   
stdlkta.dksGsTavtvlvsekhliianlGDsRavlcrng.....kaaflteDHkpsrpkEkkRieqAGGsvv.vsRvnGaLAvsRalGDyeykeeeek

--GKPVVICTPNGAGIddwqpHRLEHSEatWLVVASDGLWDFVVDDQVMSIVAKN--QHLDHSAIAKKLIDEARLCGSEDDITIIVVRY
   .  |.  |. . |     .| |. .  .||.|.||.|| . |..|...|.|.  .. . ...||.|.|.|   ||.| ....|| .
kaeeqlvsaepevtsi.....erseedd..flvlacDGiwDvlsdeevvelvrkrlevadeleevakalvdkalekgsrDNlsvlvvlf
PP2C Protein phosphatase 2C 20-193 2.5e-35 115.3 Pfam-A 89-255 (255) alignment 
Range on Protein: 20-193
Range on HMM: 89-255/255.0
ER-AK-SANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgvnpVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGK
.. .. .. .. ||... ....|...|. |.|||.|.|.. ....    .||.| | .. ..||.|| .|||..   | | |.|  || .|| ..| . .
ksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsnngrvngsLavsRalGdfelkpkee

PVVICTPNGAgiddwqPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKNQHL--DHSAIAKKLIDEARLCGSEDDI
..|.. |.         ..|. .    |..||||||| . |......| .. .   . . .|..|.|||   ||||.|
qlvsaePdvt......svkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedni
PP2C Protein phosphatase 2C 20-193 2.5e-35 115.3 In-house 89-255 (255) alignment 
Range on Protein: 20-193
Range on HMM: 89-255/255.0
ER-AK-SANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgvnpVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGK
.. .. .. .. ||... ....|...|. |.|||.|.|.. ....    .||.| | .. ..||.|| .|||..   | | |.|  || .|| ..| . .
ksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsnngrvngsLavsRalGdfelkpkee

PVVICTPNGAgiddwqPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKNQHL--DHSAIAKKLIDEARLCGSEDDI
..|.. |.         ..|. .    |..||||||| . |......| .. .   . . .|..|.|||   ||||.|
qlvsaePdvt......svkltee.defliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaiargsedni
PPM_PTC7 20-193 1.9e-33 109.0 In-house 90-259 (259) alignment 
Range on Protein: 20-193
Range on HMM: 90-259/259.0
ER-AKS-ANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHgvnpVELNERHGTNLKSERKRILAAGGKIAP--DGSVYGVLFPSRGFGDIDVKAD
.. ... . .| ||. . ... ||..|. |.|||.|.|.. ....    ..|.| | .....||.|| .|||..    .| |.|||  || ||| . | .
ksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavsRafGdfelkpk

G--KPVVICTPNGAgiddwqPHRLEHSeATWLVVASDGLWDFVVDDQVMSIVAKNQHL-DHSAIAKKLIDEARLCGSEDDI
   ...|...|          . .. .    |..||||||| | |... ..| .. .  | . .|.||.|||   ||||.|
eteeqlvsaePdis......stkidee.defliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdeaiargsedni
subfamily_TAB1_pd Subfamily TAB1 20-89 2.2e-06 19.7 In-house 118-187 (333) alignment 
Range on Protein: 20-89
Range on HMM: 118-187/333.0
ERAKSANDTAGSCSTAV--VVKGSQVYCGNAGDSKALLFQINEthGVNPVELNERHGTNLKSERKRILAAGG
|| .. ..     .|||  ..   ..|  |.|||.||| . .|    . . |.  | |. . | .|.   | 
erlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGl
subfamily_PPM1H_pd Subfamily PPM1H 20-85 5.3e-06 18.4 In-house 152-211 (404) alignment 
Range on Protein: 20-85
Range on HMM: 152-211/404.0
ERAKSANDTAGSCSTAVV-VKGSQVYCGNAGDSKALLFQINEThgvnpVELNERHGTnlKSERKRIL
.| ..|  ..| |.. |. |   ..|  |||||.|.| . .|.     ..| . .    ..||.|..
arereayrikGGCtalvalvllgklYvanaGDsRailvrkdei.....iplsadftP..eteRqRlq
subfamily_PPM1K_pd Subfamily PPM1K 23-200 2.9e-19 62.2 In-house 92-258 (263) alignment 
Range on Protein: 23-200
Range on HMM: 92-258/263.0
KSANDTAGSCSTAVVV-KGSQVYCGNAGDSKALLFQINEThgvnpVELNERHGTNLKSERKRILAAGGKIAPDG----SVYGVLFPSRGFGDIDVKADGk
..   ..|. .| ... .| ..   . |||.|.| .  ..       | . |  .|. |..||.||||... .      | |.|  .| .||.|.|  | 
eaellssGttatvsllrdGtelvlaslGdsrailcrnGka.....kkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGdldlkryG.

pvVICTPNGAGIddwqphRLEHSEATWLVVASDGLwDFVVDDQVMSIVAKNQHlDHSAIAKKLIDEARLCGSEDDITIIVVRY
  || ||.   .      ...|.. ..||. .||. .|||..| .. . .  | |    |. | . |   ||||. |..|| .
..viatPetksl......kvdhaadsflvlitdgi.sfvvnsqelcdlvrlch.dpeeaahalteqalqygsednatavvvpl
subfamily_PDP_pd Subfamily PDP 23-115 1.3e-12 40.5 In-house 146-243 (398) alignment 
Range on Protein: 23-115
Range on HMM: 146-243/398.0
KSANDTAGSCSTAVVVKGSQVYCGNAGDSKALLFQINETHGVNPVELNERHGTNLKSERKRILAAGGKI-----APDGSVYGVLFPSRGFGDIDVKAD
. .  ..|.|.......| ...  |.||..|.| . .|.  .. |.|.. . .. ..| .|| ..  .        .| . | |.|.| |||.  | .
allvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKws
PPM_PTC7_SpoIIE 26-200 9.3e-16 51.3 In-house 88-229 (230) alignment 
Range on Protein: 26-200
Range on HMM: 88-229/230.0
NDTAGSCSTAVVVKGSQ--VYCGNAGDSKALLFQINEThgvnpvelnerhgtnlksERKRIlAAGGKIA---PDGSVYGVLFPSRGFGDIDVKAdGKPVV
... |.. . ... .|.  .|. ||||| .||.. ...                  ||.|| .||| .     .|.|.|||  |. .||. ...    ||
psssgaTavvalidpstgklyvanaGdsppllvrddgg..................ereri.vagglpslGilpgrvfgvlavslapGdlllly.tDGvv

ICTPNgagiddwQPHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDhsaiakklidearLC--GSEDDITIIVVRY
 . |        ... .  ..   |..||||||| . .......| .. .               ..  . |||||..||| 
eaepd.......tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp.............aaeglleDDitllvvrv
subfamily_PPM1G_pd Subfamily PPM1G 27-183 3.2e-18 59.0 In-house 294-447 (473) alignment 
Range on Protein: 27-183
Range on HMM: 294-447/473.0
DTAGSCSTAVVVKGSQVYCGNAGDSKALLFQInethGvNPVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGKpVVICTPNG
  .|.  . ...|. ...  |||||.. | .     | . ..| . |  . . |..|| .||||.  || | | |  || .||   | . . .       
edsGttAvvaLlkekklivAnaGDsRcvlsrn....G.kAldlslDHkPeDevEleRiekAGGkvdedgRvnGGLnlsRAlGDhaYkknee.Lplkeqmi

AGIDDWQPHRLEHsEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDH----SAIAKKLIDE
. . | . . | . |  .||.|.||.|. .  ..|.  | .. .  .    |.| ..|.|.
sAlPDikvltlte.edeFlvlAcDGiWnvmesqevvdfvraklkkgeesvlseiveeLlDa
PP2C_SIG_SM00331 29-199 5.9e-10 32.1 In-house 87-216 (217) alignment 
Range on Protein: 29-199
Range on HMM: 87-216/217.0
AGSCSTAVV-VKGSQVYCGNAGDSKALLFQinETHGVNPVELnerhgtnlkserkrilaaggkiapdgsvygvlfpsrgfgdidvkadgkpvviCTPNGA
  ..  |..  ......  |||||  .|..  . . | ...                                                      ... .
faTlllalydfssgklsyanaGdsrpyllr..dgklveilkd....................................................vegapl

GIDD---WQPHRLEHSEATWLVVASDGLWDFV-----VDDQVMSIVAKNQHLDHSAIAK----KLIDEARLCGSEDDITIIVVR
|. .    . . || ..   |. ..|||.. .      ..... |......  . ..|.    .|. .|. .. |||||..||.
GlepevsvdirelelekgdllllytDGltearsekgfaeerleeiledlvdseaqelaqkiveellelakgsngeDdiTvvvvk
subfamily_PP2D1_pd Subfamily PP2D1 30-168 1.2e-12 40.4 In-house 177-305 (492) alignment 
Range on Protein: 30-168
Range on HMM: 177-305/492.0
GSCSTAVVVKGSQVYCGNAGDSKALLFQinEthGVNpVELNERHGTNLKSERKRILAAGG---KIAPDGSVYGVLFPSRGFGDIDvKADGKPVVICTPNG
 . |    .. . .|  |||. .|.| .  |  |.  . |   | .. | ||.|.  ||.   |  . | | |.|   || | .    . |  ||. |. 
sngsevhleelgvlyianaGnvqAvLcr..e..Gka.iiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGnyG.dpkLkksvipePkt

AGIddwqphRLEHsEATWLVVASDGLWDFVVDDQVMSIVAKN
  .       |.. .|  ||.|| |||. . ...|.|.| . 
tsv......klde.aaqflvlAsnGlWevlseeevlsLvkqt
subfamily_KAPP-like_pd Subfamily KAPP-like 36-199 1.1e-12 40.6 In-house 109-265 (266) alignment 
Range on Protein: 36-199
Range on HMM: 109-265/266.0
VVVKGSQVY--CGNAGDSKALLFQINEThgvnpVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGKpVVICTPNGAgiddwq
|  .| | |  ..| ||| |.| . ||.     .||   | .. ..|..||   |  .. . .    |  || .||  .|      .| .|  .      
vwsdGqqrylqvanvGdssaflsrGnes.....lelskdhkakdpeekqrikddGitlsdnqtrinGlavsralGdhfikelni.Glisepyvs......

PHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAK--NQHLDHSAIAKKLIDEAR-LCGSEDDITIIVVR
.. |      .|.|||||||| .  .. . .|    .|.  .  .|. |.. |     . |....|||.
nrilltpfdkflivasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvk
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 43-199 5.1e-12 38.2 In-house 128-275 (276) alignment 
Range on Protein: 43-199
Range on HMM: 128-275/276.0
VYCGNAGDSKALLFQINEThgvnpVELNERHGTNLKSERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVKADGKpVVICTPNGAgiddwqPHRLEHSEA
. ..| ||| |.| . ||.     .||   | ..  .|..||   |  .. . .    |  || .||  .|      .| .|  .      .. |     
lqvanvGdssaflsrGnes.....lelskdhkatdpeekqrikddGitlsdnqtrinGlavsralGdhfikelni.Glisepyvs......nrilltpfd

TWLVVASDGLWDFVVDDQVMSIVAK--NQHLDHSAIAKKLIDEAR-LCGSEDDITIIVVR
 .|.|||||||| .  .. . .|    .|.  .  .|. |.. |     . |....|||.
kflivasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvk
subfamily_PHLPP_pd Subfamily PHLPP 65-200 1.1e-08 27.2 In-house 124-245 (246) alignment 
Range on Protein: 65-200
Range on HMM: 124-245/246.0
NPVELNERHGTNLKsERKRILAAGGKIAPDGSVYGVLFPSRGFGDIDVkadgKPVVICTPNGAGIddwqphRLEHsEATWLVVASDGLWDFVVDDQVMSI
... |....  .   | |||  | . |  |. . ||.  .| .| . .     |||. .|.   .       |.. .  .|.| .. ||. .  |.. . 
kklrlsksyviekd.elkrikeakaiitednkingviestrllGytfl....fPvvlPkphvrev......lLte.qdellivGnkalWevlsideavea

VAKNQhlDHSAIAKKLIDEARLCGSEDDITIIVVRY
| |..  |  ..||||.| |   | .|.....|||.
vrkee..dplvaAkklvdlaqsygaadsvsvlvvrl
subfamily_PPM1H_pd Subfamily PPM1H 103-185 7.2e-10 31.2 In-house 283-374 (404) alignment 
Range on Protein: 103-185
Range on HMM: 283-374/404.0
PSRGFGDIDVKADG-----KPVVICTPNgagIDDWQPHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAK-------NQHLDHSAIAKKLIDEAR
 .||.|| ..|.       ||.. ..|.   .  .. . .|..|   |..|.||||| . ...|  ||..       ...  ..|.|..|. .||
vtRGlGDheLkvvdtnlsikPfLspvPe...vrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedkkrytavaqeLvaaar
SpoIIE Stage II sporulation protein E (SpoIIE) 130-200 4.7e-07 21.8 Pfam-A 112-192 (193) alignment 
Range on Protein: 130-200
Range on HMM: 112-192/193.0
DDWQPHRLEHSEATWLVVASDGLWDFVVDDQV-------MSIVAKNQHLDHSAIAKKLIDEARLCG---SEDDITIIVVRY
 |.. ..|.  .   |....||. .   .|.        ....|.... . ......|..|.. .|    |||||..|.|.
adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveellelgsgeleDDitllvlrv
SpoIIE Stage II sporulation protein E (SpoIIE) 130-200 4.7e-07 21.8 In-house 112-192 (193) alignment 
Range on Protein: 130-200
Range on HMM: 112-192/193.0
DDWQPHRLEHSEATWLVVASDGLWDFVVDDQV-------MSIVAKNQHLDHSAIAKKLIDEARLCG---SEDDITIIVVRY
 |.. ..|.  .   |....||. .   .|.        ....|.... . ......|..|.. .|    |||||..|.|.
adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesleelldalveellelgsgeleDDitllvlrv
PPM_PTC7_SpoIIE_motif 132-201 6.7e-12 38.9 In-house 2-81 (81) alignment 
Range on Protein: 132-201
Range on HMM: 2-81/81.0
WQPHRLEHSEATWLVVASDGLW-------DFVVDDQVMSIVAKNQHLDHSAIAKKLIDEARLCG---SEDDITIIVVRYD
.. ....  .   |....|||.       ... ............. .   .|.||.||.. .|   .|||||..|.|.|
ydeaefqLkpgdvllLyTDGltEardsdgelfgkeellrladraegkslqeladklvdevlengsgereDDitllvlrvd
subfamily_PPM1D_pd Subfamily PPM1D 134-174 1.7e-06 20.4 In-house 230-270 (309) alignment 
Range on Protein: 134-174
Range on HMM: 230-270/309.0
PHRLEHSEATWLVVASDGLWDFVVDDQVMSIVAKNQHLDHS
 ..|. .|  ....||||||. .  ....|.| |...    
vrtldpneekfiilasDGlwnvltpedavsvvekeeekkel
subfamily_PDP_pd Subfamily PDP 140-175 2.4e-06 19.9 In-house 283-316 (398) alignment 
Range on Protein: 140-175
Range on HMM: 283-316/398.0
SEATWLVVASDGLWDFVVDDQVMSIVAknQHLDHSA
..  .||.|.|||||.. ...|.|.|   .||....
endkFLvlatDGLwdllsneevvslVg..ehlakkk
PPM_PTC7_motif 146-193 3.4e-09 30.1 In-house 1-51 (51) alignment 
Range on Protein: 146-193
Range on HMM: 1-51/51.0
VVASDGLWDFVVDDQVMSIVAKNQHL---DHSAIAKKLIDEARLCGSEDDI
. ||||||| . |... ..| .. .    .   .|.||.|||.  ||||.|
iLAsDGLWDvlsdqeavdlvrdqlskkglspqeaAeklvdealargseDni