Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPP6C_pd | Subfamily PPP6C | 1-134 | 3.2e-77 | 252.5 | In-house | 156-289 (290) | alignment | ||
Range on Protein: 1-134
Range on HMM: 156-289/290.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP
.|.||.|... |.| ||.|.|..|||||||||||||||||.|.|||.||||||.||| |||.|||.||||||||||||||.||.|||||||||||||||
lcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsap
NYCYRCGNIASILAFSDADNREPKLFQAVPDYER
||||||||.|||||..||..||.|||.|||| ||
nycyrcgnvasilaledaeereaklfkavpdeer
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 1-130 | 1.3e-59 | 194.8 | In-house | 157-286 (288) | alignment | ||
Range on Protein: 1-130
Range on HMM: 157-286/288.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP
.| || | | | ||.|||. |.||.|..|||.|||||....||.||||||.||| .|...|.. |...||||||||| ||||..|.||..||||||
fcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsap
NYCYRCGNIASILAFSDADNREPKLFQAVP
||||||||.|.|| . .. ... |.|.|..
nycyrcgnvaaileldeeldkdfkifeaaa
|
|||||||||
PPP_3 | 1-127 | 2e-42 | 138.0 | In-house | 143-270 (271) | alignment | |||
Range on Protein: 1-127
Range on HMM: 143-270/271.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDL-VWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.. || | . . | |....|..|.|..|...|| ..||||. .... |.||||.||||.||.||.. |.||||.|||.|..|||....|.|.|||.||
lvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSa
PNYCYRCGNIASILAFSDADNREPKLFQ
||||.|..| ..|| ...|...|.|...
pnycerasnagailkleealtsefkqle
|
|||||||||
PP2Ac_SM00156 | 1-127 | 5.3e-39 | 126.9 | In-house | 141-268 (271) | alignment | |||
Range on Protein: 1-127
Range on HMM: 141-268/271.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDP-EEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.| || |. .. . | || ..|. |.|..| ..||.|||| ........| ||.. .||.....||.. ||||||.|||..|.|||....|.||||..||
lcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsa
PNYCYRCGNIASILAFSDADNREPKLFQ
||||....| |..| .... . . ....
pnycdefsnkaavlkveknlklsieqlk
|
|||||||||
PPP_1 | 1-113 | 4.9e-36 | 117.4 | In-house | 142-262 (264) | alignment | |||
Range on Protein: 1-113
Range on HMM: 142-262/264.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDL--------VWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEK
.. || | . | ||...|..|.|..|..||| ...|.|. ...| |.||||.|||..||..|.. ||||||.|||....|||......|
livHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrk
LVTVWSAPNYCYRCGNIASIL
.||..||.||.....| ....
vvtifsasnyyeegsnrgayv
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 1-116 | 2.4e-34 | 111.8 | In-house | 150-266 (282) | alignment | ||
Range on Protein: 1-116
Range on HMM: 150-266/282.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.| || | .. . ||.| | .|.|.|| |||.||||.. | .|. . || . ||..| ..|.. |.|.||.||||.|..||... ...||||.||
lcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsa
PNYCYRCGNIASILAFS
|||| . .| ...|. .
pnycgefdnagavlsvd
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 1-116 | 7.8e-34 | 110.3 | In-house | 186-302 (317) | alignment | ||
Range on Protein: 1-116
Range on HMM: 186-302/317.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.| || . . . . ...| ..|| | .||.|.||. ||.... |.|||| .||.| .||.. .|.|. ||||.|..||... | ||||..||
lcmhGGiseelldlkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsa
PNYCYRCGNIASILAFS
|.|| . |||..|
psycGqldniaavlsvd
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 1-116 | 5.1e-33 | 107.7 | In-house | 154-270 (284) | alignment | ||
Range on Protein: 1-116
Range on HMM: 154-270/284.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.|.|| . . . . ..| ..|| | .||.|.||| ||.... |||||| .||.| .||.. .|.|. ||||.| .||... | ||||..||
icmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsa
PNYCYRCGNIASILAFS
| || . |||..| .
psycgqldniaavlnvd
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 1-116 | 3.9e-30 | 97.9 | In-house | 165-281 (298) | alignment | ||
Range on Protein: 1-116
Range on HMM: 165-281/298.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.| || | . .. | .|.. | .. ... ||.|.|||. | || . ||.. || .| ..... .. |..||||.| .||... . ||||..||
lcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsa
PNYCYRCGNIASILAFS
|.|| . | |... .
phycgqfdnsaavmkvd
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 1-116 | 1.4e-28 | 92.8 | In-house | 146-262 (280) | alignment | ||
Range on Protein: 1-116
Range on HMM: 146-262/280.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.|.|| | . |. | .. . | .. ... ||.|.||| .| || ..||. .|| .| ..... .. ||.| ||.| .||... | |||||.||
lcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsa
PNYCYRCGNIASILAFS
|.|. | |..| .
pkylgefdnsaavlivd
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 1-116 | 7.3e-27 | 87.4 | In-house | 165-281 (299) | alignment | ||
Range on Protein: 1-116
Range on HMM: 165-281/299.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.|.|| | . | | .| . | .. | ||.|.||.. | | || ..||..| .. .. .. |..||||.| .||... . ||||..||
lcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsa
PNYCYRCGNIASILAFS
| || . | |.|.
phycgqfdnsaaimkvd
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 1-115 | 1.3e-24 | 80.0 | In-house | 205-320 (339) | alignment | ||
Range on Protein: 1-115
Range on HMM: 205-320/339.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVD-TWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
||.|| . . . . . . | .||| | . || |.||. . . | ||| ..||| . |.. .|... | ||.| .||... .|||..||
mcmhggisehltsfnqfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsa
PNYCYRCGNIASILAF
|||| . | |....
pnycgqndntaavfsi
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 1-115 | 2.2e-24 | 79.4 | In-house | 146-261 (280) | alignment | ||
Range on Protein: 1-115
Range on HMM: 146-261/280.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.|.|| | . | || | | | .| . ||.|||| . . | | || ..|| | .. .. .. || ||||.|..||. | .|.||.|
lcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsv
PNYCYRCGNIASILAF
|||| . | |.....
pnycaqftnaaavvcl
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 1-117 | 1.4e-23 | 76.9 | In-house | 165-282 (300) | alignment | ||
Range on Protein: 1-117
Range on HMM: 165-282/300.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE-VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.| || | . | || . | ..| | ||.|||| . . | || . . ..|.| . |.|||| .| .||... | ||||.||
fcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsa
PNYCYRCGNIASILAFSD
|||| | .... |.
pnycgefdnwgavmsvse
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 1-118 | 2.3e-23 | 75.5 | In-house | 150-271 (287) | alignment | ||
Range on Protein: 1-118
Range on HMM: 150-271/287.0
MCFHGNLKTRSVTHDPIRTIDRNMEI--PHKGAFCDLVWSDPEE-VDTWAIS-PRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTV
.| || . . . | .... . ..| ||.|.|||. .| .. |. .|| |. ..... ...|| |||....|||...||..||||
lcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtv
WSAPNYCYRCGNIASILAFSDA
.||| |. . |..... |..
fsapyysgedtnlgavvvvsks
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 1-118 | 3.5e-22 | 71.8 | In-house | 181-312 (452) | alignment | ||
Range on Protein: 1-118
Range on HMM: 181-312/452.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEV-DT-------WAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFD--
.| || | . . | |...|| |.|..|..|||.|||| | . |.|| .... | . ||.. |.| | |||. ..||. .
lcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkse
----EKLVTVWSAPNYCYRCGNIASILAFSDA
|.|..|||||. | |..| . .
atgfPslitlfsapnyldvynnkaavlkyenn
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 1-118 | 1.4e-21 | 69.8 | In-house | 156-278 (290) | alignment | ||
Range on Protein: 1-118
Range on HMM: 156-278/290.0
MCFHGNLKTRSVTHDPIRTIDRN--MEIPHKGAFCDLVWSDPEE--VDTWAIS-PRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVT
.|.|| . . . . .... . ..| ||.|.||.. || |. |. .|| |. ..... |.|| |||.. .||....||.||||
lcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvt
VWSAPNYCYRCGNIASILAFSDA
|.||| |. . |. .|. |..
vfsapyysgndtnlgaiatvses
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 1-115 | 5e-21 | 68.2 | In-house | 163-278 (307) | alignment | ||
Range on Protein: 1-115
Range on HMM: 163-278/307.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSA
.|.|| | | .| . . | .| |..|.||. | | | ||.|. || .| .. .. ..|| ||||.. .|| . ||.|..||
lcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsa
PNYCYRCGNIASILAF
| || | .|
pmycnfyknagcvlkv
|
|||||||||
PPP_4 | 1-80 | 8.8e-21 | 67.8 | In-house | 114-196 (197) | alignment | |||
Range on Protein: 1-80
Range on HMM: 114-196/197.0
MCFHGNLKTRSVTHDPIRTIDRNMEIP-HKGAFCDLV-WSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQL
...|| | . | |..|.|..|.| ......|| ||||. . ...| | ||||.||||.||..|.. ||||||.|.|.|
lvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 1-115 | 9.2e-21 | 67.4 | In-house | 164-281 (297) | alignment | ||
Range on Protein: 1-115
Range on HMM: 164-281/297.0
MCFHGNLKT---RSVTHDPIRTIDRNMEIpHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTV
.|.|| | . .| | .| |.|. | ... .||.|.|| . . |||| || . . .| |.|||||.|..||... ||||.
lcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvti
WSAPNYCYRCGNIASILAF
.||| || . | |....
fsaphycgqfdncaafmsc
|
|||||||||
PPP_5_Dcr2 | 1-80 | 5e-20 | 65.3 | In-house | 115-198 (199) | alignment | |||
Range on Protein: 1-80
Range on HMM: 115-198/199.0
MCFHGNLKTRSVTHDPIRTIDRNMEIP-HKGAFCDLV-WSDPE-EVDT-WAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQL
...|| | . . .. |.|..||| .|| .||. ||||. .... .. | ||||.||||.||..|.. ||||||.|.|.|
lvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
PPP_2 | 1-80 | 1.8e-19 | 63.2 | In-house | 113-197 (198) | alignment | |||
Range on Protein: 1-80
Range on HMM: 113-197/198.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDL-----VWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQL
.. || | . . | |....|..|.|..|...|| .....|. ...| | ||||.||||.||.|... |.||||.|||..
lvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 1-113 | 7.9e-19 | 61.1 | In-house | 144-258 (284) | alignment | ||
Range on Protein: 1-113
Range on HMM: 144-258/284.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHKGAF-CDLVWSDPEEVD-TWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWS
.|.|| . .|.| | .. | .. |..|||| ... | || ..|| ..... .. |. ||||.|..||... . .|||..|
lcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifs
APNYCYRCGNIASIL
|| || . | |...
apfycgqfdnaaavm
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 1-113 | 3.3e-16 | 52.3 | In-house | 161-284 (302) | alignment | ||
Range on Protein: 1-113
Range on HMM: 161-284/302.0
MCFHGNLKTRSVTHDPIRTIDRNM-EIPHKGAFCDLVWSDPEEVDTWAISP----------RGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMF
.| || . . . . |. |.| . |. . ||...|| .|.. |. . || .| ... . ||||| |||| . ||.|..
lcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffa
DEKLVTVWSAPNYCYRCGNIASIL
|.||.|..|||.| | ..|
dkklltifsaprymnesdnkGavl
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 1-113 | 3.8e-16 | 52.1 | In-house | 162-285 (302) | alignment | ||
Range on Protein: 1-113
Range on HMM: 162-285/302.0
MCFHGNLKTRSVTHDPIRTIDRNM-EIPHKGAFCDLVWSDPEEVDTWAISP----------RGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMF
.|.|| . . . . |. |.| . |. . ||...|| .|.. |. . || .| ... . ||||| |||| . ||.|..
lcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffa
DEKLVTVWSAPNYCYRCGNIASIL
|.||.|..|||.| | ..|
dkklltifsaprymnesdnkGavl
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 1-114 | 5.8e-16 | 51.9 | In-house | 125-241 (263) | alignment | ||
Range on Protein: 1-114
Range on HMM: 125-241/263.0
MCFHGNLKTRSVTHDPIRTIDRNMEIPHK-GAFCDLVWSDPEEvDTWAISP---RGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTV
.|.|| . . . | ||.| .| . |||.|.|||. |. . | | .|| | ..... .. || ||||.| || .. | .|.||
lcmhggisphlkslddiraiplpletakthplacdllwadpek.dakgfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitv
WSAPNYCYRCGNIASILA
.|| | | |...
fsasryqielcnyaavvv
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 2-130 | 2e-48 | 158.1 | In-house | 159-287 (290) | alignment | ||
Range on Protein: 2-130
Range on HMM: 159-287/290.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPN
|.|| | . | | ||..|| |.||.|..|||.||||.. . |.|||||||. || .....| . |.|.|| |||||| |||....|...||..||||
clhgglspsidtldkiraldrlqevphegplcdllwsdpddrggwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapn
YCYRCGNIASILAFSDADNREPKLFQAVP
||||||| |.|| . |. ... |.. |
ycyrcgnqaailelddklkysflqfdpap
|
|||||||||
0045823 | Metallo-dependent phosphatases | 2-134 | 1.8e-45 | 148.6 | In-house | 184-329 (473) | alignment | ||
Range on Protein: 2-134
Range on HMM: 184-329/473.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDT--------WAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEK-
. || | . | ||.|.| |||. |...||.||||.|.| . ||||||.||||....|| . |.|.||.|.|. | |||...|| |
fvHGGlspdlplldqireierpleipddgllldllwsdPweddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkv
-----LVTVWSAPNYCYRCGNIASILAFSDADnREPKLFQAVPDYER
..||.||||||.|.|| |..| ... .....|...|. .
igiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpli
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 2-131 | 3.2e-42 | 137.8 | In-house | 157-298 (300) | alignment | ||
Range on Protein: 2-131
Range on HMM: 157-298/300.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEE------------VDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMF
| || | . | |. .|| |.|..||..||.|||||| . . .|.||||. .| .|...|.. |... | |||||..|||. .|
cvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilf
DEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVPD
|.|| |||||||||||||| |||| . |.| . ... |.
dnklstvwsapnycyrcgnkasilelyekderyfnvyeeape
|
|||||||||
0049330 | Metallo-dependent phosphatases | 2-135 | 1.2e-41 | 136.1 | In-house | 171-305 (309) | alignment | ||
Range on Protein: 2-135
Range on HMM: 171-305/309.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP
| || | .. | || ..| .|||. | .|||.|||| .....| .|||.|..||. ....|...|.|.||.|.|..|..||...||.||.||.|||
cvHgGlspdlllldqirelerpleipldgllcdllwsdplpiregfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsap
NYCYRCGNIASILAFSDADNREPKLFQAVPDYERV
|||.|.|| ...| ... .....||..|| . ..
nycgrlgnlgavleidedlvisfllfepvplllll
|
|||||||||
0053225 | Metallo-dependent phosphatases | 2-130 | 1.2e-40 | 132.9 | In-house | 164-292 (293) | alignment | ||
Range on Protein: 2-130
Range on HMM: 164-292/293.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPN
. || | .. | || |.| ..||. |...||.|||| ....|..|.||.|..||. ....|...|.|.||.|.||.|..||...||.|||||.||||
fvHgGlspdlslldqireinrplriplegllldllwsdpdlwsgwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapn
YCYRCGNIASILAFSDADNREPKLFQAVP
|..|.|| ...||... ....||| .|.
ylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 2-131 | 1.3e-36 | 119.3 | In-house | 180-311 (322) | alignment | ||
Range on Protein: 2-131
Range on HMM: 180-311/322.0
CFHGNL-KTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPEEVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP
|| | .. .|| | .|.||||.. |..|....|.||||.| . | || | ||| ||..|.. |||.|| |.|.. .|||. . | ||.||.|||
vvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsap
NYCYRCGNIASILAF-SDADNREPKLFQAVPD
||| . || .... . .| .. . | |.||.
nycdqmgnkgafitlrgddlklkfktfeaveh
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 2-117 | 2.1e-27 | 89.0 | In-house | 149-265 (281) | alignment | ||
Range on Protein: 2-117
Range on HMM: 149-265/281.0
CFHGNLKTRSVTHDPIRTIDRNMEIPHKGAFCDLVWSDPE-EVDTWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAP
| || | .. | .| . . .. ...| ||.|.||. .| | | ||....|| .| .. .. || ||||.|..||. . ||.||.|.|
cmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvp
NYCYRCGNIASILAFSD
||| | |..| .
nycafyknaaavlkvde
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 32-127 | 5.6e-20 | 64.4 | In-house | 237-331 (383) | alignment | ||
Range on Protein: 32-127
Range on HMM: 237-331/383.0
FCDLVWSDPEEVD-TWAISPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFsdADNREPKLFQ
|..||||.. . .. . ||.| ||| ||..... ||||. |.|. .|||... |.|..|..|| || | . . . ... .|...|
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl..gkdltprivq
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 49-113 | 4.4e-12 | 38.9 | In-house | 210-274 (290) | alignment | ||
Range on Protein: 49-113
Range on HMM: 210-274/290.0
SPRGAGWLFGPKVTQEFVNINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
. || | .|. . . |.. |||. . |||. ..|... . .|.||.|. .|| . | ||
drrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalil
|