Gene PPP6C-2 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP6C
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP122_AA protein Get Run
NvecP122_AA_1-259 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 2-258 2.1e-97 319.7 In-house 28-329 (473) alignment 
Range on Protein: 2-258
Range on HMM: 28-329/473.0
ADLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKW
 |||..|.. |....|||.||.||.|...|.| .|.|....| ...|.||||||..||..|..  |  |.. .||.||.||||..|||.. .|| || |.
ldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkiky

PDRITLLRGNHESRQITQVYGFYDECQSKYgNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR--------------------------
|....|||||||.|.....|||.||.  || ... ......... | .||.|.|..|.||||||||....|| |                          
pgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwedd

---------------GAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEK------LVTVWSAPNYCYRCGNIASILAFSDADnREPKLFQAVP
               |||.||||. ..|| . |.|.||.|.|. | |||...|| |      ..||.||||||.|.|| |..| ...   .....|...|
gdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsp

DYER
.  .
hpli
subfamily_PPP2C_pd Subfamily PPP2C 2-174 3.6e-84 275.4 In-house 2-174 (290) alignment 
Range on Protein: 2-174
Range on HMM: 2-174/290.0
ADLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKW
 |||..|.  |||. | |...|.||. . |.| .|||||.|..|||||||.||||.|| |||. ||..|.| |.|.||.|||||||.|| | | .|| ..
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry

PDRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
..|||.||||||||||||||||||||  |||||| |.|  ..|| |...|..|.|..|.|||||| |.|.|. 
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldki
subfamily_PPP6C_pd Subfamily PPP6C 3-173 8.3e-111 362.7 In-house 1-171 (290) alignment 
Range on Protein: 3-173
Range on HMM: 1-171/290.0
DLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWP
.||.||..||.|.||||||||||||.|..|||||||||||||||||||||||||||||||||||||||.|||||.|||||||||||||||||||||||.|
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp

DRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
|||||||||||||||||||||||||..||||||||.||.|||||||.|||||.||||||||||||.||.||
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldq
0049330 Metallo-dependent phosphatases 3-259 1.4e-92 303.1 In-house 16-305 (309) alignment 
Range on Protein: 3-259
Range on HMM: 16-305/309.0
DLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWP
.||..|.. . . .|.|..|..|.....|.|..|.|....| ...|.||||||..||..|..  | .|.. .||.||.||||..|||....|| || ..|
lldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllyp

DRITLLRGNHESRQITQVYGFYDECQSKYGnANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR---------------------------
|...|||||||.|.....|||.||.. ||| |. |........ | .||.|.|..||||||||||....|| |                           
dnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpire

-------GAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVPDYERV
       |.|..||.  ...|...|.|.||.|.|..|..||...||.||.||.||||||.|.|| ...| ...  .....||..|| . ..
gfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplllll
0053225 Metallo-dependent phosphatases 3-254 7.4e-89 291.0 In-house 8-292 (293) alignment 
Range on Protein: 3-254
Range on HMM: 8-292/293.0
DLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWP
.||..|.. . . .|.|..|..|.....|.|..|.|....| ...|.|||||...||..|..  | .|.. .||.||.||||..|||....|| ||...|
lldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllyp

DRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS----------------------------
|...|||||||.......|||.||.  |||.|. |........ | .||.|.|..|.||||||||. ..||                             
dnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlwsg

-----RGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVP
     ||.|..||.  ...|...|.|.||.|.||.|..||...||.|||||.|||||..|.|| ...||...  ....||| .|.
wlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
subfamily_PPP4C_pd Subfamily PPP4C 3-175 4.5e-88 288.2 In-house 2-174 (288) alignment 
Range on Protein: 3-175
Range on HMM: 2-174/288.0
DLDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWP
|||| |.  ..|| . |...|.||  . |.|.|||||| | |||||||||||||||| |||. ||.||.|.|.|.|||||||.||.|||  ||.||...|
dldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvryp

DRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
|||||.||||||||||||||||||| .|||.|| ||||..|||.|..||||||...||||||||.|.|.|. |
dritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeir
subfamily_PPG1_pd Subfamily PPG1 4-173 2.9e-75 246.3 In-house 1-171 (300) alignment 
Range on Protein: 4-173
Range on HMM: 1-171/300.0
LDRWIDIAKECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPD
||. ..  . .| |||  .|.|.| . |||..||||. . ||||| ||.||||||. |.|. |||||.| |.|.||.||||.||.|| . |..|| ..| 
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps

RITLLRGNHESRQITQVYGFYDECQSKY-GNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
||||||||||||||||||||| ||  || ||.. |.|  ..|| |..||||| .. ||||||||....|||
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidq
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 12-174 1.5e-51 168.2 In-house 19-181 (298) alignment 
Range on Protein: 12-174
Range on HMM: 19-181/298.0
KECEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGN
| .. . |.|..||.. . ... . . .  | .|..||||||||. ||  ||  .|  |.. |.|.||.|||| ..||. . ||. |.|.|... |||||
kltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGn

HESRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
||  .| .|||||.||. .| . . .    .||. | ..|.| |..||.|||||. .|..|| 
heceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldql
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 14-168 4.7e-44 143.8 In-house 20-174 (297) alignment 
Range on Protein: 14-168
Range on HMM: 20-174/297.0
CEYLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHE
.. . |. . || |   ...  . ..  | .|. ||||||||| ||  ||. ||  | . |.|.||.|||| .|.||   ||. | |.|  . |||||||
skviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhe

SRQITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDI
   . .|||||.||| .|     .     ||. | .. .|  ..||.|||||| .
cefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglspll
subfamily_PPP1C_pd Subfamily PPP1C 16-173 5.9e-60 195.8 In-house 9-165 (282) alignment 
Range on Protein: 16-173
Range on HMM: 9-165/282.0
YLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESR
 | |.....|...  |.||... .  .. ||...||||||..||  || |.|  |...|.|.||.||||  |||| . ||..| |.|... |||||||| 
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesa

QITQVYGFYDECQSKYGNAnAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
.|...|||||||. .|..   |.   .||. | .||..| ..|||||||||..| ..|
sinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleq
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 16-173 1.9e-41 135.4 In-house 7-169 (284) alignment 
Range on Protein: 16-173
Range on HMM: 7-169/284.0
YLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQV------PNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLR
 | |..| .||    ||. .|.  . . .||...||||||| ||  |.   |         .. |.|.||.|||| .|.|  | |...| ..||...|||
llkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllr

GNHESRQITQVYGFYDECQSKYGNAnAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
|||||| . . |||| ||. .| .|  .      |  . ..|... ...|.|||.| |.  ..|
gnhesrpvnmqygfyleckkrysea.lyeafqlafnamplcavvskkiicmhggisedlldlkq
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 16-67 2e-09 30.1 In-house 8-59 (317) alignment 
Range on Protein: 16-67
Range on HMM: 8-59/317.0
YLPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGG
 . |..| .||    ||. .|     . .|||..||||||| ||  |.   |
lfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
PPP_3 17-174 4.7e-73 238.5 In-house 2-159 (271) alignment 
Range on Protein: 17-174
Range on HMM: 2-159/271.0
LPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQ
|.||.||.|.. . |.| .|||.. .|.|||||||||||..|| |||..||..|.|.|.|.||.||||..|||... ||.|| |.|....||||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

ITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
|..||||..|...|.|... ......||.||..||.||..||.|||||||.||..|| 
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqi
subfamily_PPP3C_pd Subfamily PPP3C 17-173 2.7e-56 184.2 In-house 41-196 (452) alignment 
Range on Protein: 17-173
Range on HMM: 41-196/452.0
LPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQ
| |..  |. . ...|| .|...  |..|.||.|||||||||| .||  ||.  .|.|.|.||.|||||.|.|.   |..|| ..|... |||||||.| 
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrh

ITQVYGFYDECQSKYGNaNAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
.|. . | .||..||.. . .  |.. || | .||....| |||||||||.||..|.
lteyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeiksldd
subfamily_PPZ_pd Subfamily PPZ 17-175 4.2e-44 144.2 In-house 25-182 (300) alignment 
Range on Protein: 17-175
Range on HMM: 25-182/300.0
LPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQ
| .... ..|    ||.| . ..  .| .| . ||.|||. ||  ||   |  | . |.|.||.||||  ||||   ||  | |.|. . |||||||  .
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecan

ITQVYGFYDECQSKyGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
.|.||||||||. .  | . |.     |. | .|||. |...|||||||| ....|. |
vtrvygfydeckrr.cnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeir
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 17-173 2e-42 138.3 In-house 6-161 (280) alignment 
Range on Protein: 17-173
Range on HMM: 6-161/280.0
LPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQ
. | |.... . . ..|. .. .  | .||.||||.|||. ||  ||   .  |.. |.|.||.|||| . ||    ||. |...|... .||||||  .
ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevis

ITQVYGFYDECQSKYGNAnAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
| . |||.||.. .| .|  .    ...| | ..|.. |..||.|||||......|.
inrkygfkdevkrrysla.lynefqelldslplvalvsgrilcmhgglsqklvsldd
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 17-175 6.2e-39 127.1 In-house 3-161 (284) alignment 
Range on Protein: 17-175
Range on HMM: 3-161/284.0
LPENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQ
.| .|.. |  ...... ..  .  | ||. .|||||||| ||  ||   |    . |.|.||.|||| . |||   |.. |  .|... .||||||   
ippedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecsl

ITQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
| ..||||.||| .| .   .     ||  . ..|..  ..||.|||.|  .. . | |
inkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlr
PP2Ac_SM00156 18-175 1.7e-63 207.2 In-house 2-158 (271) alignment 
Range on Protein: 18-175
Range on HMM: 2-158/271.0
PENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQI
 ......|.. |.|.| .|.|.  ||.||||.||||||..|| .|....|..|.. |||.||.||||..|.|. . |..|| ..|....||||||||...
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv

TQVYGFYDECQSKYgNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
...|||..|.. || .....  . ..|.||..||..| ..||.||||||.....|. |
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddir
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 18-175 4.3e-46 150.5 In-house 25-182 (299) alignment 
Range on Protein: 18-175
Range on HMM: 25-182/299.0
PENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQI
 |..|..||.   . ..... .  | .|. ||||||||. ||  .|   |  |.. ..|.||.||||   ||. | ||  | |.|.|. .||||||   |
keqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpai

TQVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
 .|||||.||. .|  .  |    . |. . .. .| ...||.|||||| ..|.|| |
nrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlr
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 18-173 1.6e-34 112.5 In-house 7-176 (302) alignment 
Range on Protein: 18-173
Range on HMM: 7-176/302.0
PENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGG------Q-----VPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRIT
 ...| .|.. | ||| .|...  .|.|||. ||||||| ||  .. .        .       .  .||.||.||||. |.|  . ...||  .| .  
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LLRGNHESRQITQVYGFYDECQSKYGNAN---AWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
|||||||.. |   ||| .| . ..|...    |.   .||  . .||..  ..||||||.|| ......
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesled
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 18-173 2e-34 112.2 In-house 8-177 (302) alignment 
Range on Protein: 18-173
Range on HMM: 8-177/302.0
PENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGG------Q-----VPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRIT
 ...| .|.. | ||| .|...  .|.|||. ||||||| ||  .. .        .       .  .||.||.||||. |.|  . ...||  .| .  
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LLRGNHESRQITQVYGFYDECQSKYGNAN---AWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
|||||||.. |   ||| .| ....|...    |.   .||  . .||..  ..||||||.|| ......
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesled
PPP_1 19-174 3.3e-72 235.9 In-house 3-158 (264) alignment 
Range on Protein: 19-174
Range on HMM: 3-158/264.0
ENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQIT
|. |..|.. . ||| .|.|.. ||...||||||||||.|| .||..||..|.|.|.|.||.||||..|.|... ||.|| |.|....||||||||||.|
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt

QVYGFYDECQSKYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
.||||..|.. |..... ......|||.|..||.||...|.|||||||.....|| 
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqi
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 19-63 6.6e-06 18.4 In-house 13-57 (339) alignment 
Range on Protein: 19-63
Range on HMM: 13-57/339.0
ENDLKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELF
  .| .||    ||.  |  .  . .|. | ||||||| ||  ..
aaelaelchrareliwsepiflkleapicvmgdihgqfddllaml
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 22-175 3.5e-40 131.2 In-house 11-163 (280) alignment 
Range on Protein: 22-175
Range on HMM: 11-163/280.0
LKKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVY
.  .   |  ...||||.    .|. | |||| |. |.. ||   |.||.   .|.||.||||   .| .  |. || .. ||| |||||||.  . ..|
iiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiy

GFYDECQSKYGNANAWRYCcKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
||| ||| ||| .  | .   .|. . ....|  .|||.||||||..  .|  |
gfyvecqykygvglwwdfq.scfnrmpmsgliskrvlcmhgglspelinldtir
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 23-174 1.6e-43 142.0 In-house 14-164 (281) alignment 
Range on Protein: 23-174
Range on HMM: 14-164/281.0
KKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYG
...   |  .. ||...  . .|..| ||.|.|| ||..||   |.||.. .||.||.||||  |||..  |.||| ...||| |||||||  .. ..||
envireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvnkiyg

FYDECQSKYGNaNAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
|| ||. |||  . |    . |. | ..| |. .|||.||||||.. ..|. 
fyvecvtkyGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldel
subfamily_PPPLV_pd Subfamily PPPLV 23-169 1.9e-37 122.1 In-house 3-155 (290) alignment 
Range on Protein: 23-169
Range on HMM: 3-155/290.0
KKLCDYVCELLLEESNVQPVSSPVTVCGDIHGQFYDLE----ELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQIT
  |||   . |..| .. .. ||. | ||.||.. ||      |.||| ..  .|..|.||.|||| .|.|  . ||.||  .| .. ||||||| . ..
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq

QVYGFYDECQSKYGNA--NAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIK
. . .. |.. |.|.   ..|    .||| | .||.|| .|.|||.|.   |.
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraim
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 31-175 1.2e-41 135.6 In-house 24-167 (287) alignment 
Range on Protein: 31-175
Range on HMM: 24-167/287.0
ELLLEESNVQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSK
|.|   . .  | .|.|..||||||. ||  .|   |. |.. |.|.||.||||  |||    |..|| ..| .. ||||||| ..| ..|||..| . |
eileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkkinklyGfkeelkrk

YGnANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
..  . ..   .||. |.. |... ..||.|||.||..|..|. .
rq.erlykqfndvfselplcarvskrilcmhGGispklksldslk
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 39-172 5.5e-37 120.4 In-house 38-170 (290) alignment 
Range on Protein: 39-172
Range on HMM: 38-170/290.0
VQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYgNANAWR
.  | .|... ||||||. .| . |   |. |.  ..|.||.||||  |||    |. .| ... .. ||||||| |.. ..|||..|   |  ... |.
lleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvnrlygfkeelarkr.gsrlwk

YCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTID
   .||. |.. | .. ..||.|||.|..|.. .
qyqdvfaelslcarvgrkilcmhggisqkieswe
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 39-174 6.8e-34 110.4 In-house 42-179 (307) alignment 
Range on Protein: 39-174
Range on HMM: 42-179/307.0
VQPVSSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGN--ANA
.  .  |. | ||.|||| || ..|   |. |.| ||| ||.||||  |||.   |.| |  .|. | |||||||  .. . ||||.|| .   .   . 
lvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvtsipkcgeei

WRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
|    ..|. | ..|.|  ..||.|||||| .  .|. 
walfqrcfnnlpisaliatkilcmhgglspaltcldel
subfamily_PPP7C_pd Subfamily PPP7C 42-166 1.8e-30 98.9 In-house 62-189 (383) alignment 
Range on Protein: 42-166
Range on HMM: 62-189/383.0
VSSPVTVCGDIHGQFYDLEELF-RTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKY--GNANAWR
.|  ||||||.||.. ||  .. . |   .. .||| |||||||  |.|    ||.|   .|  . | |||||   .   |||  | .|||   ...  |
iskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilr

YCCKVFDLLTVAAIIDGQVLCVHGGLSP
   .||  | .|..|| ..| ||||.| 
lledvfawlplatlidekilivhGGisd
subfamily_PPP5C_pd Subfamily PPP5C 43-166 4.6e-40 130.6 In-house 64-187 (322) alignment 
Range on Protein: 43-166
Range on HMM: 64-187/322.0
SSPVTVCGDIHGQFYDLEELFRTGGQV-PNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNAnAWRYCC
.. .||||||||||||| ..|.  |.. .. .|.| ||||||| .|.|.   ||..|  .|... | |||||| .. ..||| .|...|| ..       
tkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfegevkakytek.vadlft

KVFDLLTVAAIIDGQVLCVHGGLSP
.||. | .| .|. .|| |||||  
evfnwlPlahvinekvlvvhGGlfs
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 43-175 3.7e-33 108.3 In-house 6-142 (263) alignment 
Range on Protein: 43-175
Range on HMM: 6-142/263.0
SSPVTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNANA----WR
 .|. .||| |||. ||  .| . |   .| |.|.||.|||| .|||    |..||   | .. ||||||| . | . |||. | . ..   .     . 
qapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvyn

YCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSR
.  .||  . ..||.  ..||.|||.|| .|..|. |
hfnqvfsymplcaivskrilcmhggisphlkslddir
Metallophos Calcineurin-like phosphoesterase 45-203 5.3e-44 143.9 Pfam-A 2-197 (200) alignment 
Range on Protein: 45-203
Range on HMM: 2-197/200.0
PVTVCGDIHGQFYDL----EELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRL--LTLKAKWPDRITLLRGNHESRQITQVYGFYDECQS---------
...|.||.||...||    ..|.. ... ... ..|.||.|||| .|.||. .|  | || . |... ||||||||......|||..|. .         
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------KYGNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTIDQSrgAGWLFGPRLTQEFVHINNLKLICRAHQ
                        .... .|.......|..|  .|..||..|..||.||.. .. |.   ...||||. . ..   ....|..|.|.
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi..gselfgpdalekllekygvdlvlrGHt
PPP_2 46-174 1e-59 194.5 In-house 1-129 (198) alignment 
Range on Protein: 46-174
Range on HMM: 1-129/198.0
VTVCGDIHGQFYDLEELFRTGGQVPNTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKVFD
||||||.|||..|| .||..|...|...|.|.||.||||..|||... ||.|| ..|....||||||||.....||||..|...|.|..........||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

LLTVAAIIDGQVLCVHGGLSPDIKTIDQS
||..||.||..||.||||||..||..|| 
lLplaalidekvlvvHGGlseeiklldqi
PPP_4 46-174 3.8e-54 176.7 In-house 1-130 (197) alignment 
Range on Protein: 46-174
Range on HMM: 1-130/197.0
VTVCGDIHGQFYDL-EELFRTGGQVP-NTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKyGNANAWRYCCKV
|||.||||||..||  .|...||. . ..||||.||.||||..|||... || || . |....||||||||......|||..|...|  ..........|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv

FDLLTVAAIIDGQVLCVHGGLSPDIKTIDQS
||||..||.||..||.||||||......|. 
fdllplaalidekvlvvhgglsdelesldki
PPP_5_Dcr2 46-173 1e-53 175.3 In-house 1-130 (199) alignment 
Range on Protein: 46-173
Range on HMM: 1-130/199.0
VTVCGDIHGQFYDL-EELFRTGGQVP-NTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNANAWRYCCKV
||||||.|||..||  .||..||. . ...|||.||.||||..|||... || || . |....|||||||..|....|||..|..|||...........|
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FDLLTVAAIIDGQVLCVHGGLSPDIKTIDQ
|| |..||.||..||.|||||||.||.|..
fdwlPlaalidekvlvvhgglspeiksiel
subfamily_YNL217W_pd Subfamily YNL217W 46-115 1.3e-06 21.1 In-house 12-77 (235) alignment 
Range on Protein: 46-115
Range on HMM: 12-77/235.0
VTVCGDIHGQFYDLEELFR--TGGQVPNTSYVFMGDFVDRGYYSLETFTRLltlkakWPDRITLLRGNHESR
. | ||.|| . .| ||.   .||. .|   |..||....|  |.|.   .        |    ..||||  
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheel
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 71-173 4.3e-32 104.5 In-house 100-201 (317) alignment 
Range on Protein: 71-173
Range on HMM: 100-201/317.0
NTSYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYGNaNAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKT
.  |.|.||.|||| .|.|  . |..|| ..||...||||||||| . . |||| |.. .| . . .    ..|  | ..|... ..||.|||.| ..  
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelld

IDQ
..|
lkq
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 73-173 1.5e-25 83.0 In-house 121-220 (339) alignment 
Range on Protein: 73-173
Range on HMM: 121-220/339.0
SYVFMGDFVDRGYYSLETFTRLLTLKAKWPDRITLLRGNHESRQITQVYGFYDECQSKYgNANAWRYCCKVFDLLTVAAIIDGQVLCVHGGLSPDIKTID
 |.|.||.|||| .|.|    | .||  .|||| ||||||||| .   |||| | . .| .|. .    ..|... ..|.|.  ..|.|||.|  . ...
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry.daqlyecfqnmfnvfpfcavinntimcmhggisehltsfn

Q
|
q
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 171-238 2.6e-14 46.2 In-house 213-280 (297) alignment 
Range on Protein: 171-238
Range on HMM: 213-280/297.0
IDQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILA
... ||||  ||     . .   .| |.|||||.|..||...   ||||..||| || .  | |....
menqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafms
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 172-240 1.1e-20 67.1 In-house 234-302 (317) alignment 
Range on Protein: 172-240
Range on HMM: 234-302/317.0
DQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
. .|||| .||..  .||..  .|.|. ||||.|..||... | ||||..|||.|| .  |||..|   
esarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvd
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 172-240 2.3e-20 66.2 In-house 202-270 (284) alignment 
Range on Protein: 172-240
Range on HMM: 202-270/284.0
DQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
.  |||| .||..  .||..  .|.|. ||||.| .||... | ||||..||| || .  |||..|  .
esprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvd
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 172-240 1.2e-15 50.4 In-house 194-262 (280) alignment 
Range on Protein: 172-240
Range on HMM: 194-262/280.0
DQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
..|||.  .||    .....  .. ||.| ||.| .||... | |||||.|||.|.    | |..|  .
ensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivd
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 172-242 1e-14 47.3 In-house 208-278 (290) alignment 
Range on Protein: 172-242
Range on HMM: 208-278/290.0
DQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDA
.. |.   .|| .  .....   |.|| |||.. .||....||.|||||.||| |. .  |. .|.  |..
nkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvses
subfamily_PPZ_pd Subfamily PPZ 172-241 1.5e-12 40.7 In-house 213-282 (300) alignment 
Range on Protein: 172-241
Range on HMM: 213-282/300.0
DQSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSD
|. ||  . .     ..|.    . |.|||| .| .||... |  ||||.||||||    |  .... |.
dnergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvse
PPP_3 173-251 1e-28 93.1 In-house 192-270 (271) alignment 
Range on Protein: 173-251
Range on HMM: 192-270/271.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQ
..||||.||||. |.||.. |.||||.|||.|..|||....|.|.|||.||||||.|..| ..|| ...|...|.|...
skrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
PP2Ac_SM00156 173-251 1.1e-23 76.7 In-house 191-268 (271) alignment 
Range on Protein: 173-251
Range on HMM: 191-268/271.0
QsRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQ
. ||.. .||.. ..||.. ||||||.|||..|.|||....|.||||..||||||....| |..| .... . . ....
k.rglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlk
subfamily_PPP5C_pd Subfamily PPP5C 173-255 2.2e-20 65.9 In-house 228-311 (322) alignment 
Range on Protein: 173-255
Range on HMM: 228-311/322.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAF-SDADNREPKLFQAVPD
 .|| |  ||| .|..|.. |||.|| |.|.. .|||. . | ||.||.|||||| . || .... . .| .. . | |.||. 
skrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeaveh
subfamily_PPP1C_pd Subfamily PPP1C 173-240 1.3e-19 63.5 In-house 199-266 (282) alignment 
Range on Protein: 173-240
Range on HMM: 199-266/282.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
..||  . ||..  ..|.. |.|.||.||||.|..||... ...||||.|||||| . .| ...|. .
ndrGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvd
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 173-240 3.7e-17 55.3 In-house 214-281 (298) alignment 
Range on Protein: 173-240
Range on HMM: 214-281/298.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
.|||..  ||    .....  .. |..||||.| .||... . ||||..|||.|| .  | |...  .
nsrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvd
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 173-242 1.1e-15 50.4 In-house 202-271 (287) alignment 
Range on Protein: 173-242
Range on HMM: 202-271/287.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDA
. |.   .|| .  .....  ...|| |||....|||...||..||||.||| |. .  |.....  |..
kiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvsks
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 173-241 8.1e-15 47.8 In-house 197-265 (281) alignment 
Range on Protein: 173-241
Range on HMM: 197-265/281.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSD
 |||....||  . ..     .. || ||||.|..||. .   ||.||.|.||||    | |..|   .
ssrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvde
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 173-238 2e-14 46.5 In-house 254-319 (339) alignment 
Range on Protein: 173-238
Range on HMM: 254-319/339.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILA
 .||| ..|||   . |..  .|... | ||.| .||...   .|||..|||||| .  | |....
sargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 173-237 7.6e-12 38.2 In-house 194-258 (284) alignment 
Range on Protein: 173-237
Range on HMM: 194-258/284.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
.|||  ..||    ....   .. |. ||||.|..||... . .|||..||| || .  | |...
nsrgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavm
subfamily_PPPLV_pd Subfamily PPPLV 173-237 3.3e-11 36.0 In-house 210-274 (290) alignment 
Range on Protein: 173-237
Range on HMM: 210-274/290.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
..|| | .|.    . |.. |||. . |||.  ..|...  . .|.||.|. .||    . | ||
drrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalil
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 173-239 3.7e-11 35.7 In-house 212-278 (307) alignment 
Range on Protein: 173-239
Range on HMM: 212-278/307.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAF
 |||.|. ||  . .. ..   ..|| ||||.. .||  .   ||.|..||| ||    |   .|  
ssrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkv
subfamily_PPP3C_pd Subfamily PPP3C 173-242 2.8e-09 29.3 In-house 237-312 (452) alignment 
Range on Protein: 173-242
Range on HMM: 237-312/452.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFD------EKLVTVWSAPNYCYRCGNIASILAFSDA
. ||  .... . . ||.. |.|  | |||.  ..||.   .        |.|..|||||.    | |..| . . 
svrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn
PPP_2 173-204 5.6e-09 29.0 In-house 166-197 (198) alignment 
Range on Protein: 173-204
Range on HMM: 166-197/198.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQL
..||||.||||. |.|... |.||||.|||..
sarGagllfgpdvteelleknklkliiRaHev
PPP_4 173-204 1.4e-08 28.0 In-house 165-196 (197) alignment 
Range on Protein: 173-204
Range on HMM: 165-196/197.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQL
. ||||.||||. |..|.. ||||||.|.|.|
svrGagllFgpdvtekfleknnlkliirshel
PPP_5_Dcr2 173-204 1e-07 25.2 In-house 167-198 (199) alignment 
Range on Protein: 173-204
Range on HMM: 167-198/199.0
QSRGAGWLFGPRLTQEFVHINNLKLICRAHQL
. ||||.||||. |..|.. ||||||.|.|.|
seRGagllfgpdvtekfleknnlkliirshel
subfamily_PPP6C_pd Subfamily PPP6C 174-258 5.2e-49 159.9 In-house 205-289 (290) alignment 
Range on Protein: 174-258
Range on HMM: 205-289/290.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVPDYER
.||||.||| ..|.||||||||||||||||||.||.|||||||||||||||||||||||.|||||..||..||.|||.|||| ||
prgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdeer
subfamily_PPP4C_pd Subfamily PPP4C 174-254 1.2e-34 112.9 In-house 206-286 (288) alignment 
Range on Protein: 174-254
Range on HMM: 206-286/288.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVP
 ||||.||| . ...|.. |...||||||||| ||||..|.||..||||||||||||||.|.|| . .. ... |.|.|..
prgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaa
subfamily_PPP2C_pd Subfamily PPP2C 174-254 6.2e-28 90.8 In-house 207-287 (290) alignment 
Range on Protein: 174-254
Range on HMM: 207-287/290.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVP
 ||||. ||  ....| . |.|.|| |||||| |||....|...||..||||||||||| |.|| . |. ...   |.. |
prgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpap
subfamily_PPG1_pd Subfamily PPG1 174-255 3.6e-27 88.4 In-house 217-298 (300) alignment 
Range on Protein: 174-255
Range on HMM: 217-298/300.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFSDADNREPKLFQAVPD
 ||||. .|  ....|.. |... | |||||..|||. .||.|| |||||||||||||| ||||   . |.|  . ... |.
qrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeape
PPP_1 174-237 2.9e-24 78.8 In-house 199-262 (264) alignment 
Range on Protein: 174-237
Range on HMM: 199-262/264.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
 ||||.|||.. |..|.. ||||||.|||....|||......|.||..||.||.....| ....
iRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayv
subfamily_PPP7C_pd Subfamily PPP7C 174-251 1.3e-14 46.7 In-house 256-331 (383) alignment 
Range on Protein: 174-251
Range on HMM: 256-331/383.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFsdADNREPKLFQ
 ||.|  ||| .|.....  ||||. |.|.  .|||... |.|..|..|| ||     |  . . .  ... .|...|
lrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl..gkdltprivq
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 174-240 1.6e-14 46.9 In-house 215-281 (299) alignment 
Range on Protein: 174-240
Range on HMM: 215-281/299.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAFS
 ||  ..||. . .. ..  .. |..||||.| .||... . ||||..||| || .  | |.|.   
vrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvd
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 174-239 5e-12 38.9 In-house 196-261 (280) alignment 
Range on Protein: 174-239
Range on HMM: 196-261/280.0
SRGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASILAF
 ||  ..||  . .. ..  .. || ||||.|..||. |   .|.||.| |||| .  | |.....
irgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvcl
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 175-237 3.6e-11 35.8 In-house 222-284 (302) alignment 
Range on Protein: 175-237
Range on HMM: 222-284/302.0
RGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
||   .|     ... .  ||||| |||| . ||.|.. |.||.|..|||.|     |  ..|
rglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavl
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 175-237 3.9e-11 35.7 In-house 223-285 (302) alignment 
Range on Protein: 175-237
Range on HMM: 223-285/302.0
RGAGWLFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
||   .|     ... .  ||||| |||| . ||.|.. |.||.|..|||.|     |  ..|
rglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavl
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 180-237 4.2e-08 26.2 In-house 183-240 (263) alignment 
Range on Protein: 180-237
Range on HMM: 183-240/263.0
LFGPRLTQEFVHINNLKLICRAHQLVHEGYKYMFDEKLVTVWSAPNYCYRCGNIASIL
.|| .  .....  .. || ||||.|  || .. | .|.||.||  |     | |...
vfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavv