Gene NvecPPM-Un-1 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP125_AA protein Get Run
NvecP125_AA_3-133 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
SpoIIE Stage II sporulation protein E (SpoIIE) 4-133 9.8e-13 40.4 Pfam-A 65-192 (193) alignment
Range on Protein: 4-133
Range on HMM: 65-192/193.0
SFCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKPIGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQE
 .. .|..  ||..| |  . ...||.  |. . |..   |.|. ..   . ... || ||.||... ..||  ..   | .. |  .|| ||| | ..|
vlaeydpstgkleyanaGhpppllvrpdggtkfllvstglplGilpe...adyeeaelqlepgdllllyTDGvtEar.dpdgelfgkerllallaeaege

KLPIQMARIELEFDRwKGNHEQIDDVLLIGVKV
.|  .. ..  |. .  |..|. ||. |. ..|
sleelldalveelle.lgsgeleDDitllvlrv

SpoIIE Stage II sporulation protein E (SpoIIE) 4-133 9.8e-13 40.4 In-house 65-192 (193) alignment
Range on Protein: 4-133
Range on HMM: 65-192/193.0
SFCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKPIGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQE
 .. .|..  ||..| |  . ...||.  |. . |..   |.|. ..   . ... || ||.||... ..||  ..   | .. |  .|| ||| | ..|
vlaeydpstgkleyanaGhpppllvrpdggtkfllvstglplGilpe...adyeeaelqlepgdllllyTDGvtEar.dpdgelfgkerllallaeaege

KLPIQMARIELEFDRwKGNHEQIDDVLLIGVKV
.|  .. ..  |. .  |..|. ||. |. ..|
sleelldalveelle.lgsgeleDDitllvlrv

PPM_PTC7_SpoIIE 5-86 6.1e-07 22.5 In-house 97-178 (230) alignment
Range on Protein: 5-86
Range on HMM: 97-178/230.0
FCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKP-IGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFGGpSSKKFM
.. .| .  |||.| |  . ...||.  || . ...   | .|...    . | . ...|..||... ..||. .     .| . .
validpstgklyvanaGdsppllvrddggererivagglpslGilpg...rvfgvlavslapGdllllytDGvveaepd.tsdgel

PP2C_SIG_SM00331 8-132 9.7e-07 21.6 In-house 95-216 (217) alignment
Range on Protein: 8-132
Range on HMM: 95-216/217.0
LDLHAMKLYFA-GAKNAAYVVRKGELIELKGD--RKPIGFDEHEGasrFTTIELALEKGDMIYTFSDGYADQFGGPSskkFMVKRLKALLIEQ-SQEKLP
.|.   ||..|    .  |..|.|.|.|   |   .|.|. ...    ... || |||||..   .||  .         |  .||. .| .  ..|.  
ydfssgklsyanaGdsrpyllrdgklveilkdvegaplGlepevs...vdirelelekgdllllytDGltearsekg...faeerleeiledlvdseaqe

IQMaRIELEFDRWKGNHEQIDDVLLIGVK
..  .|  |  . ...... ||. .. ||
laq.kiveellelakgsngeDdiTvvvvk

subfamily_YNL217W_pd Subfamily YNL217W 36-129 1.4e-22 73.3 In-house 83-208 (235) alignment
Range on Protein: 36-129
Range on HMM: 83-208/235.0
KGDRKPIGFDEHEGASRFTTIELALEKGDMIYTFSDGYA------DQFG---GPSSKKFM-------VKRLKALLIE------QSQEKLPIQMARIELEF
|  .||.|....|..|.|...|..|.|.||.|....|..      ....   |....||.       |..|..||..      .|.|| ..|.|||.|..
kwvkkpkgaeplefsskfsflesklskadmeyarelgfsldipsdellvvhaGlvpgkfleensidevlslrnllvdkknlsktseekeakqiariqlwa

DRWKGN------HEQIDDVLL----I
..||||      |..|... |    .
elWkgnakvyfGHdaieglqlyrfat

PPM_PTC7_SpoIIE_motif 53-133 4e-06 20.4 In-house 2-80 (81) alignment
Range on Protein: 53-133
Range on HMM: 2-80/81.0
FTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQEKlPIQMARIELEFDRWKGNHEQIDDVLLIGVKV
. . |. |..||..  ..||  ..   . .. | ...| .|. ...... . ..|.  ..  .  |..|. ||. |. ..|
ydeaefqLkpgdvllLyTDGltEar.dsdgelfgkeellrladraegks.lqeladklvdevlengsgereDDitllvlrv