Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
SpoIIE | Stage II sporulation protein E (SpoIIE) | 4-133 | 9.8e-13 | 40.4 | Pfam-A | 65-192 (193) | alignment | ||
Range on Protein: 4-133
Range on HMM: 65-192/193.0
SFCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKPIGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQE
.. .|.. ||..| | . ...||. |. . |.. |.|. .. . ... || ||.||... ..|| .. | .. | .|| ||| | ..|
vlaeydpstgkleyanaGhpppllvrpdggtkfllvstglplGilpe...adyeeaelqlepgdllllyTDGvtEar.dpdgelfgkerllallaeaege
KLPIQMARIELEFDRwKGNHEQIDDVLLIGVKV
.| .. .. |. . |..|. ||. |. ..|
sleelldalveelle.lgsgeleDDitllvlrv
|
|||||||||
SpoIIE | Stage II sporulation protein E (SpoIIE) | 4-133 | 9.8e-13 | 40.4 | In-house | 65-192 (193) | alignment | ||
Range on Protein: 4-133
Range on HMM: 65-192/193.0
SFCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKPIGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQE
.. .|.. ||..| | . ...||. |. . |.. |.|. .. . ... || ||.||... ..|| .. | .. | .|| ||| | ..|
vlaeydpstgkleyanaGhpppllvrpdggtkfllvstglplGilpe...adyeeaelqlepgdllllyTDGvtEar.dpdgelfgkerllallaeaege
KLPIQMARIELEFDRwKGNHEQIDDVLLIGVKV
.| .. .. |. . |..|. ||. |. ..|
sleelldalveelle.lgsgeleDDitllvlrv
|
|||||||||
PPM_PTC7_SpoIIE | 5-86 | 6.1e-07 | 22.5 | In-house | 97-178 (230) | alignment | |||
Range on Protein: 5-86
Range on HMM: 97-178/230.0
FCALDLHAMKLYFAGA-KNAAYVVRK--GELIELKGDRKP-IGFDEHegaSRFTTIELALEKGDMIYTFSDGYADQFGGpSSKKFM
.. .| . |||.| | . ...||. || . ... | .|... . | . ...|..||... ..||. . .| . .
validpstgklyvanaGdsppllvrddggererivagglpslGilpg...rvfgvlavslapGdllllytDGvveaepd.tsdgel
|
|||||||||
PP2C_SIG_SM00331 | 8-132 | 9.7e-07 | 21.6 | In-house | 95-216 (217) | alignment | |||
Range on Protein: 8-132
Range on HMM: 95-216/217.0
LDLHAMKLYFA-GAKNAAYVVRKGELIELKGD--RKPIGFDEHEGasrFTTIELALEKGDMIYTFSDGYADQFGGPSskkFMVKRLKALLIEQ-SQEKLP
.|. ||..| . |..|.|.|.| | .|.|. ... ... || |||||.. .|| . | .||. .| . ..|.
ydfssgklsyanaGdsrpyllrdgklveilkdvegaplGlepevs...vdirelelekgdllllytDGltearsekg...faeerleeiledlvdseaqe
IQMaRIELEFDRWKGNHEQIDDVLLIGVK
.. .| | . ...... ||. .. ||
laq.kiveellelakgsngeDdiTvvvvk
|
|||||||||
subfamily_YNL217W_pd | Subfamily YNL217W | 36-129 | 1.4e-22 | 73.3 | In-house | 83-208 (235) | alignment | ||
Range on Protein: 36-129
Range on HMM: 83-208/235.0
KGDRKPIGFDEHEGASRFTTIELALEKGDMIYTFSDGYA------DQFG---GPSSKKFM-------VKRLKALLIE------QSQEKLPIQMARIELEF
| .||.|....|..|.|...|..|.|.||.|....|.. .... |....||. |..|..||.. .|.|| ..|.|||.|..
kwvkkpkgaeplefsskfsflesklskadmeyarelgfsldipsdellvvhaGlvpgkfleensidevlslrnllvdkknlsktseekeakqiariqlwa
DRWKGN------HEQIDDVLL----I
..|||| |..|... | .
elWkgnakvyfGHdaieglqlyrfat
|
|||||||||
PPM_PTC7_SpoIIE_motif | 53-133 | 4e-06 | 20.4 | In-house | 2-80 (81) | alignment | |||
Range on Protein: 53-133
Range on HMM: 2-80/81.0
FTTIELALEKGDMIYTFSDGYADQFgGPSSKKFMVKRLKALLIEQSQEKlPIQMARIELEFDRWKGNHEQIDDVLLIGVKV
. . |. |..||.. ..|| .. . .. | ...| .|. ...... . ..|. .. . |..|. ||. |. ..|
ydeaefqLkpgdvllLyTDGltEar.dsdgelfgkeellrladraegks.lqeladklvdevlengsgereDDitllvlrv
|