Gene CG9801 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP136_AA protein Get Run
NvecP136_AA_30-209 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CG9081_pd Subfamily CG9081 29-210 2.8e-94 304.8 In-house 1-192 (195) alignment 
Range on Protein: 29-210
Range on HMM: 1-192/195.0
AGEPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFT---ASNTHDVFNLLLKSFEFAQSCIIKNSATMTTLCTAVVAELEG--
||||||||||||||.||.|..|||||.||.|.||||||||||.|.|||..||.   ..|..|.|.|||.|.|.||..|..||.|.|||..|||.||..  
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilensgtlttlsiavvcelkank

--TNQWGLCVLNVGDSLAFVYNKNNG-VREITIGSHCEQ--RDMRCPGGSLGPVDGYNPDLENMTFSYTTVTTGDIVFLTSDGVSDNFDPVV
  ..||||.|..||||..|||...|. |||.|..||...  ||.|..||.|||..|..|||||...||..|..|||||||||||||||||||
kissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvv
subfamily_CG9801_pd Subfamily CG9801 29-123 1.8e-26 83.1 In-house 2-102 (252) alignment 
Range on Protein: 29-123
Range on HMM: 2-102/252.0
AGEPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFT-ASNTHDVFNLLLKSFEFAQSCIIKNSATM-----TTLCTAVVAELE
.|.|.||.| || | |. |..||||. ||.....|||||.|. ..||.. |.. ......|.. ||...| | ..|...  ..     |||...|..|||
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskeittvqevgksllaaleeahksivegkselweaGtttLlggvllele

G
 
k
subfamily_tipA_pd Subfamily tipA 29-123 1.2e-15 47.1 In-house 6-105 (296) alignment 
Range on Protein: 29-123
Range on HMM: 6-105/296.0
AGEPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFTASNTHDVFNLLLKSFEFAQSCIIKNS-----ATMTTLCTAVVAELEG
.|.|.|| |.|. . |  |..||||  || . . ||..|.|. |..|..     .. .|. ..||..|| |   |..       |  |||   |..||| 
egdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflseksseintvkdaGkfllsafeaahkkiveGksdiweaGtttllGGvlleleq
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 30-211 1.7e-65 210.4 In-house 2-194 (199) alignment 
Range on Protein: 30-211
Range on HMM: 2-194/199.0
GEPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFTAS----NTHDVFNLLLKSFEFAQSCIIKNSATMTTLCTAVVAEL----
|||||||||||||.||.|...||||.|| |.|||||.|| | ..|... ||  |    |......|||.|.. |. .|.... |.|||  ||| ||    
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpns

EGTNQWGLCVLNVGDSLAFVYNK-NNGVREITIGSHCEQ--RDMRCPGGSLGPVDGYNPDLENMTFSYTTVTTGDIVFLTSDGVSDNFDPVVS
. ...|||.|  ||||  |||.  .. |.|.|.  | ..  |..|  ||.|||  | .|||||...||  |. ||||.||.||.||||.||| 
rsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvvl
PP2C_2 Protein phosphatase 2C 31-207 5e-13 41.8 Pfam-A 10-182 (212) alignment 
Range on Protein: 31-207
Range on HMM: 10-182/212.0
EPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFTASNT--HDVFNLLLKSFE-------FAQSCIIKNSATMTTLCTAVVAEl
.|  | .|.    .  ..  |||..    |. .|| ||   ...| ..| ..| .   .... ...  .        |..   . ..  |||. ||... 
kpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavitp.

egtnqWGLCVLNVGDSLAFVYNKNNGVREITIGSHCEQRDMrcpggsLGPVDGYNPDLeNMTFSYTTVTTGDIVFLTSDGVSDNFD
     ........||. ..|..... |. ...  . |   .      .  ..  ..   .. ..  ..  || ..|..|||||.. 
.....geivffqiGDgaivvrdrdgevqllgepdsgeyane......ttfltsedaee.elrirrlklepgdalllmTDGvsdslr
PP2C_2 Protein phosphatase 2C 31-207 5e-13 41.8 In-house 10-182 (212) alignment 
Range on Protein: 31-207
Range on HMM: 10-182/212.0
EPVADVFAVVARPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYLFTASNT--HDVFNLLLKSFE-------FAQSCIIKNSATMTTLCTAVVAEl
.|  | .|.    .  ..  |||..    |. .|| ||   ...| ..| ..| .   .... ...  .        |..   . ..  |||. ||... 
kpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTlllavitp.

egtnqWGLCVLNVGDSLAFVYNKNNGVREITIGSHCEQRDMrcpggsLGPVDGYNPDLeNMTFSYTTVTTGDIVFLTSDGVSDNFD
     ........||. ..|..... |. ...  . |   .      .  ..  ..   .. ..  ..  || ..|..|||||.. 
.....geivffqiGDgaivvrdrdgevqllgepdsgeyane......ttfltsedaee.elrirrlklepgdalllmTDGvsdslr
0034914 PP2C-like 34-208 3.3e-14 45.7 In-house 36-246 (295) alignment 
Range on Protein: 34-208
Range on HMM: 36-246/295.0
ADVFAVVA-----RPNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQ-YLFTASNTHDVFNLLLKSFEFAQSCIIKNSA----TMTTLCTAVVAELEG
 | . ||       .. ... ..||..  . ...|.. .|   ...|.. .|.. ....|. . | |.|  |.  ... .      ..  .||||| . |
eDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavvalirg

TNqwgLCVLNVGDSLAFVYnKNNGVREITIGSHCEQRDMR-------------------CPGGSLGPVDGY--------------NPDLENMTFSyttVT
.    | | ||||| |... .|. .. .|.  .. ....|                   .   .|| .| .               ||.  ....   . 
nk...lyvanvGDSravll.rngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvtvlelt...le

TGDIVFLTSDGVSDNFDP
 .|.. | |||..|....
dddfllLasDGlwdvlsn
PP2Cc_SM00332 34-150 2.1e-08 26.9 In-house 25-144 (274) alignment 
Range on Protein: 34-150
Range on HMM: 25-144/274.0
ADVFAVVAR----PNNCIISLADGvswgTKSRLAARSAVAGSVQYLNQYLFTASNT--HDVFNLLLKSFEFAQSCIIKNSATM-----TTLCTAVVAELE
 |...|| .     .  .....||         .|. . .  ...|.. |.. ...  .|| ..| |.|. ... | ..   .     .  .||||| | 
eDahvvvvdlveeedwlffgvfDG....hgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenalsGstavvallk

GTNqwgLCVLNVGDSLAFVYNKNNgVRE
. .   | | ||||| |....... ...
ked...lyvanvGDSravlcrngk.avq
0049733 PP2C-like 35-208 3.6e-17 55.7 In-house 20-194 (235) alignment 
Range on Protein: 35-208
Range on HMM: 20-194/235.0
DVFAVvarpNNCIISLADGVSWGTKSRLAARSAVAGSVQYLNQylftaSNTHDVFNLLLKSFEFAQSCIIKNSAT----MTTLCTAVVAELEgtnQWGLC
| ..|    .  .. .|||.. .  ...|.. .|   ...| .      ...|. ..| |.|. |...... . .    ..  .||||| |    .  |.
Davlv....glllfavaDGhgghaagevasellvetllellle.....lllldleealrkaflaaneallelalaspelagmgtTavvalld...ggkly

VLNVGDSLAFVYNkNNGVREITIGSHCEQRDMRCP----------------GGSLGpvDGYNPdlenMTFSYTTVTTGDIVFLTSDGVSDNFDP
|.||||| |.... .. .. .|   .  ... |                    .||  | .      . ....... ||...|.|||..|....
vanvGDsrayllr.dgklvqltedhspvnelerqriitaggavrvpgrlaltralG..dlllk....pdvtvlelepgdflllasDGlwdvlsd
PP2C_SIG_SM00331 35-205 5.7e-12 38.7 In-house 19-163 (217) alignment 
Range on Protein: 35-205
Range on HMM: 19-163/217.0
DVFAVVARPN-NCIISLADGVSWGTKSRLAARSAVAGSVQYLNQYlftaSNTHDVFNLLLKSFEFAqsciiknSATMTTLCTAVVAELeGTNQWGLCVLN
|.. ||. ..   .. .|||.  |  . .|.....    ..|..     ... .... | . ..         . ..   .|...|..  ...  | ..|
DyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg....eelsqalkrlnraiyee.......keekgmfaTlllaly.dfssgklsyan

VGDSLAFVYNkNNGVREITIGshceqrdmrcpggSLGPVDGYNPDLEnMTFSYTTVTTGDIVFLTSDGVSDN
.|||  .... ...  ||.                .|.. |  |... .. . ...  ||...| .||. ..
aGdsrpyllr.dgklveilkd.............vegaplGlepevs.vdirelelekgdllllytDGltea
subfamily_PPTC7_pd Subfamily PPTC7 35-206 1.4e-07 24.2 In-house 13-181 (252) alignment 
Range on Protein: 35-206
Range on HMM: 13-181/252.0
DVFAVVARPNNCIISLADGV-SWGTKSRLAarSAVAGSVQYLNQYLFTASN--THDVFNLLLKSFEfaQscIIKNSATMTTLCTAVVAELEGTNQwGLCV
| ..|  . ..... .|||| .|  .   .  |. .       . |  .|.  ...  .|| ....  .  . .. ...   .||... |.....  | .
DayfvsseksadvlgvADGVggWrsvGiDp..sefsreLmkaceklskeskaeelkPvelleaayq..e..lleekvpvlGssTacivvldksdk.kles

LNVGDSLAFVYNKNngvrEITIGSHCEQRDMRCPGGSLGPVDG----YNPDLENMT-FSYTTVTTGDIVFLTSDGVSDNF
 |.|||   |  |.    ..   |.  | .  .|     . .|    .  |  ...  .  .| .|||. | .||. || 
anlGDSgflvvRkg....kvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNl
PPM_PTC7 76-150 2.5e-06 20.1 In-house 62-136 (259) alignment 
Range on Protein: 76-150
Range on HMM: 62-136/259.0
NQYLFTASNthDVFNLLLKSFEFAQSCIIKNS-ATM----TTLCTAVVAELEGTNqwgLCVLNVGDSLAFVYNKNNGVRE
... |. ..  .. . | |||. ..  . ..| ...    |  .||||| . |..   | | ||||| | . ...| | .
erksfeele..klekalrksflaldtdeelksseantepstsGstAvvalitgsk...lyvAnvGDSravLcrsgnavkq
PPM_PTC7_SpoIIE 105-206 5e-08 26.0 In-house 87-170 (230) alignment 
Range on Protein: 105-206
Range on HMM: 87-170/230.0
KnsaTMTTLCTAVVAELEGTNqWGLCVLNVGDSLAFVYNKnNGVreitigshceqrdMRCPGGSLGPV-DGYNPDLENMTFSyTTVTTGDIVFLTSDGVS
.     .  .|||||...... . | | |.||| ...... .|               | . .. |..  |  |. .. ...  .   ||. .| .||| 
e...psssgaTavvalidpst.gklyvanaGdsppllvrd.dgg.............ererivagglpslGilpgrvfgvla.vslapGdllllytDGvv

DNF
.. 
eae
subfamily_CG9801_pd Subfamily CG9801 124-211 1.2e-34 109.9 In-house 127-216 (252) alignment 
Range on Protein: 124-211
Range on HMM: 127-216/252.0
TNQWGLCVLNVGDSLAFVYN-KNNGVREITIGSHCEQRDMRCPGGSLGP-VDGYNPDLENMTFSYTTVTTGDIVFLTSDGVSDNFDPVVS
...||... .|||..||.|. |...|..|| |.... .|.| .|| ||| |.. .|||.|.....|.|  .||..|.||||.||.||.. 
sskwgfvcasvGDckaflysakkkevtditkgnrsnlsDarDagGrLGPyveqgkPdLrnLklfftlveeeDiillvsDGvhDnlDPqtl
subfamily_tipA_pd Subfamily tipA 124-209 2.6e-19 59.1 In-house 150-237 (296) alignment 
Range on Protein: 124-209
Range on HMM: 150-237/296.0
TNQWGLCVLNVGDSLAFVYNKN-NGVREITIGSHCEQRDMRCPGGSLGP-VDGYNPDLENMTFSYTTVTTGDIVFLTSDGVSDNFDPV
. .||.    |||  || . |. . | .|| |  ..  | . ||| ||| |.  .||| |..  ....   ||..| |||| ||.|| 
sskWgfvcasvGdckafllskkskevtditkgnrsnvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPk