Gene PTC7-2 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PTC7
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP151_AA protein Get Run
NvecP151_AA_104-300 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0049733 PP2C-like 129-299 2.8e-24 78.9 In-house 70-233 (235) alignment 
Range on Protein: 129-299
Range on HMM: 70-233/235.0
FF----------------FSRTGSSTACIVVLDkrDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHYFNTPYQLAIPPPGQD--------GRVIQDSLDA
                    ... .||....||  ...|. .|.||| ....|.| .|. . ..........|  | . |           | . |.|  
kaflaaneallelalaspelagmgtTavvalld..ggklyvanvGDsrayllrdgklvqltedhspvnelerqriitaggavrvpgrlaltralGdlllk

AESTSFNVEVDDLIVMGTDGLFDNLSTDQILTEIAElqdydaESIQSLADSLAMKARClafdpsyespfakqaklrglaitGGKPDDITVLVAVV
.. |....| .|.... .|||.|.|| ..|.  ...       ... .|. |.  |.                        .|..|.|||.|. .
pdvtvlelepgdflllasDGlwdvlsdeeivdllrs......ldleeaaerlvelala.......................rggrDNiTvvvvrl
0034914 PP2C-like 129-300 2.5e-20 65.7 In-house 118-291 (295) alignment 
Range on Protein: 129-300
Range on HMM: 118-291/295.0
FFFSRTGSSTACIVVLdkRDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHYFNTPYQLAIPPPGqdgRVIQDSLD-------------------------
.   .....||.....  |...|.  |.||| ....|.| .|. . .. ..... ..  . . |   .|. . .                          
rpelagsGtTavvali..rgnklyvanvGDSravllrngelvqltvdhkpvnelererilsagg...avshgrvngvlavtRalGdfdlklllsllllep

------AAESTSFNVEVDDLIVMGTDGLFDNLSTDQILTEIAELQDyDAESiqsladslamkarclafdpsyesPFAKQAKLRGLAITGGKPDDITVLVA
         ......| ||......|||.|.|| ..|.. ...|      .                       . .   .|  ||. .|. |.|||.|.
lvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrslla.kgld.......................leeaaeeLvdlAlargsrDNiTvvvv

VVS
 ..
rln
subfamily_PPTC7_pd Subfamily PPTC7 133-300 1.9e-77 253.1 In-house 85-252 (252) alignment 
Range on Protein: 133-300
Range on HMM: 85-252/252.0
RTGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHYFNTPYQLAIPPPGQDGRVIQDSLDAAESTSFNVEVDDLIVMGTDGLFDNLSTD
  ||||||||||||.||.|.|.||||||||||||| ||..|.||||.|||||||.|.|.|..|.||.|. .||.|.||.|. .|.||..||||||||..|
vlGssTacivvldksdkklesanlGDSgflvvRkgkvvfrskeqqhkfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlled

QILTEIAELQDYDAESIQSLADSLAMKARCLAFDPSYESPFAKQAKLRGLAITGGKPDDITVLVAVVS
.||....||......|.||||..||.|||.|..||.||||||..|| .||...|||||||||.|||||
eileilkelkeseksslqslakklaekarelsldpeyespfaqkakkngleasGGKpDDitvvvavvs
SpoIIE Stage II sporulation protein E (SpoIIE) 134-297 8.2e-13 40.6 Pfam-A 59-190 (193) alignment 
Range on Protein: 134-297
Range on HMM: 59-190/193.0
TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRK-GivvhQSSEQQHYFNTPyqLAIPPPgqdgrviqdslDAAESTSFNVEVDDLIVMGTDGLFDNLSTD
    ||.....|  ...|. .|.|.. .|.||. |    .  .. . .. |  | | |              .|.... .| .||... |||.... . |
erfatavlaeydpstgkleyanaGhpppllvrpdg....gtkfllvstglp..lGilpe...........adyeeaelqlepgdllllyTDGvtEardpd

QIL----TEIAELQDYDAESIQSLADSLAMKARClafdpsyespfakqaklrglAITGGKPDDITVLVA
. |      .| |..  .|| . |.|.|  ...                     .  |.. ||||.||.
gelfgkerllallaeaegesleelldalveelle....................lgsgeleDDitllvl
SpoIIE Stage II sporulation protein E (SpoIIE) 134-297 8.2e-13 40.6 In-house 59-190 (193) alignment 
Range on Protein: 134-297
Range on HMM: 59-190/193.0
TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRK-GivvhQSSEQQHYFNTPyqLAIPPPgqdgrviqdslDAAESTSFNVEVDDLIVMGTDGLFDNLSTD
    ||.....|  ...|. .|.|.. .|.||. |    .  .. . .. |  | | |              .|.... .| .||... |||.... . |
erfatavlaeydpstgkleyanaGhpppllvrpdg....gtkfllvstglp..lGilpe...........adyeeaelqlepgdllllyTDGvtEardpd

QIL----TEIAELQDYDAESIQSLADSLAMKARClafdpsyespfakqaklrglAITGGKPDDITVLVA
. |      .| |..  .|| . |.|.|  ...                     .  |.. ||||.||.
gelfgkerllallaeaegesleelldalveelle....................lgsgeleDDitllvl
PPM_PTC7_SpoIIE 134-298 9.2e-12 38.2 In-house 90-228 (230) alignment 
Range on Protein: 134-298
Range on HMM: 90-228/230.0
TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRK-GIvvhqSSEQQHYFNTPYqLAIPPPgqdgrviqdslDAAESTSFNVEVDDLIVMGTDGLFDNL--S
.. .||.....|  . .|. .|.||| .|.||. |       |.   .. |. |.| |              ......  .  ||... |||. ..   .
ssgaTavvalidpstgklyvanaGdsppllvrddgg....ererivagglps.lGilpg...........rvfgvlavslapGdllllytDGvveaepdt

TDQIL----TEIAELQDY------DAESIQSLADSLAMKarclafdpsyespfakqaklrglAITGGKPDDITVLVAV
 | .|      .. . |       ..| .. . |.|  .                       |  |.. ||||.||. 
sdgelfgkdeflilasdglwdvlspqelvdlvrdelekp.......................aaeglleDDitllvvr
PPM_PTC7 134-179 1.6e-06 20.7 In-house 98-143 (259) alignment 
Range on Protein: 134-179
Range on HMM: 98-143/259.0
TGSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGIVVHQSSEQQHY
  .| ...||.  ....|.  |.|||.....|.| .|.| .|... 
pstsGstAvvalitgsklyvAnvGDSravLcrsgnavkqltedHkp
PP2C_SIG_SM00331 135-297 8.5e-16 51.2 In-house 86-215 (217) alignment 
Range on Protein: 135-297
Range on HMM: 86-215/217.0
GSSTACIVVLDKRDKTLHSVNLGDSGFLVVRKGIVVHQSSEqqhyfNTPYQLAIPPPGQdgrviqdsldaAESTSFNVEVDDLIVMGTDGLFDNL-----
.  |... ..| ....|. .|.||| ....|.|  |.. ..     .....| . |  .           ........| .||... ||||...      
mfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd.....vegaplGlepevs...........vdirelelekgdllllytDGltearsekgf

STDQILTEIAELQDYDAESIQS-LADSLAMKARCL-AfdpsyespfakqaklrglaitggkPDDITVLVA
 .... . ...|.|  |. ...   ..|  .|.                            .|||||.| 
aeerleeiledlvdseaqelaqkiveellelakgsng........................eDdiTvvvv
PPM_PTC7_SpoIIE_motif 205-297 3.7e-09 30.2 In-house 2-78 (81) alignment 
Range on Protein: 205-297
Range on HMM: 2-78/81.0
AESTSFNVEVDDLIVMGTDGLFDNLsTDQILT-----EIAELQDYDAESIQSLADSLAMKARClafdpsyespfakqaklrglaiT--GGKPDDITVLVA
.....| .. .|.....||||...  .... .      .. ... ...| |.||| |  ...                       .  |.. ||||.||.
ydeaefqLkpgdvllLyTDGltEar.dsdgelfgkeellrladraegkslqeladklvdevle......................ngsgereDDitllvl
subfamily_PPM1H_pd Subfamily PPM1H 208-268 1.7e-06 20.1 In-house 317-381 (404) alignment 
Range on Protein: 208-268
Range on HMM: 317-381/404.0
TSFNVEVDDLIVMGTDGLFDNLSTDQILTEIAE-LQDYD---AESIQSLADSLAMKARCLAFDPS
|... . ||.....||||.| || ..... ..| |....    .   ..| .| ..||    | .
tqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedkkrytavaqeLvaaarGklkdkg
PP2Cc_SM00332 213-296 3.9e-07 22.7 In-house 211-273 (274) alignment 
Range on Protein: 213-296
Range on HMM: 211-273/274.0
EVDDLIVMGTDGLFDNLSTDQILTEIAELQ----DYDAESIQSLADSLAMKArclafdpsyespfakqaklrglaitGGKPDDITVLV
. |..... .|||.|.|| ...   . .|     . |.. .. | | .|...                         ||. |.|||.|
sedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeairr.........................ggseDniTvvv