Gene FBP26 in Saccharomyces cerevisiae

Synonym: YJL155C, FBP26

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PFKFB
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP038_AA protein Get Run
ScerP038_AA_217-416 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
6PF2K 6-phosphofructo-2-kinase 3-224 3.5e-96 310.9 Pfam-A 3-223 (223) alignment 
Range on Protein: 3-224
Range on HMM: 3-223/223.0
YSTISNDNDIKVCVIMVGLPARGKSFISQKIIRYLSWLSIKAKCFNVGNYRRDVSGNvPMDAEFFNFENTDNFKLRELAAQNAIKDIVNFFTKEDGSVAV
.||..|... |.....||||||||..||.|..|||.||....|.||||.|||... . ..|||||...|....|||| .|..|.||.......|.|.||.
qstvknlknsklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgkyrreavka.lsdaeffrpdneealklreklalaalkdllkylneeegqvai

FDATNSTRKRRKWLKDICEKNNIQPMFLESWSNDHELIINNAKDIGSTSPDYENSEPHVAEADFLERIRQYERFYEPLDPQKDKDMTFIKLVNIIEEVVI
|||||.||.|||......|.||....||||...|.|.| .| |.. ..||||...|.. | .|||.|...||..|||||...|.....||.... ...|.
fDAtNttrerRklilefveennlkvlflesvcsdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvidvgkslvv

NKIRTYLESRIVFYVMNIRPKP
|....||.||||.|..||. ||
nnvqgylqsrivyyllNihlkp
AAA_33 AAA domain 16-125 1.3e-08 25.3 Pfam-A 2-97 (143) alignment 
Range on Protein: 16-125
Range on HMM: 2-97/143.0
VIMVGLPARGKSFISQKIIRYLSwlsikAKCFNVGNYRRDVSGnvpM---DAEffnfentDNFKLRELaAQNAIKDIVNFFTKEDGSVaVFDATNSTRKR
|..||||. |||. ...... |      .   .  ..|| . |   .   . .       |  ....  . .......    .. .|| ..|||| .|..
vllvGlpGsGKstlaerllkklg.....yvrlsqdtlrrrlfg...tdqqslt.......dytrvlkr.lyqilnklarkalsagrsv.ivdatnlsree

RKWLKDICEKNNI
|... ..... . 
rarfvklakrlgv
DUF3768 Protein of unknown function (DUF3768) 163-208 6.5e-06 12.6 Pfam-A 14-56 (84) alignment 
Range on Protein: 163-208
Range on HMM: 14-56/84.0
EADFLERIRQYERFYEPLDPQKDKDMTFIklvNIIEEVVINKIRTY
 ...|...|....| .  || . .|. ..   .. .| |. || .|
qqeilravrafddftpdnDPhgehDfGav...evegekvfwKiDyY
0037864 Phosphoglycerate mutase-like 218-407 4.7e-49 158.9 In-house 1-203 (211) alignment 
Range on Protein: 218-407
Range on HMM: 1-203/211.0
MNIRPKPKYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTANYL----P---YKKLQWKALDELDAGVC
|....... ..| ||||. .|.|... |  |. |.|.| ..|..| .....  |     |..|.|.|..|||...    .   ..  ....| |.| |..
MslnllmtrlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadl.glpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgal

DGMTYEEIEKEYPEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELERQ-----ENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRA
.|.|.|||...|||.. |. .|.| .|. ||||..||| |..|...|| ..     ||||...|..|||...||..... || ... .| .....|| . 
egltleeiaekypeelvawlrdpydfrppggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsleellrlnlpngsvtvleldd

YGTK
.| .
ggwv
subfamily_PFKFB_pd Subfamily PFKFB 219-415 2.6e-90 293.2 In-house 1-197 (198) alignment 
Range on Protein: 219-415
Range on HMM: 1-197/198.0
NIRPKPKYIWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESAGEiNLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEK
||. ||. |.|.||||| .|....|||||.|.||| .|||||.. .||.  . .|.||||.||||.|||..| ..| |||||||||||.|||.|||||..
nihlkpreiylvRhGeseknkkgriggdseLterGveyakklakfikeenlk.elrvwtselkrtiqTaellglpkeqwkaLdeldaGkcdgltyeeike

EYPEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELER-QENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKVTKIKANI
..||.||.|..|||.|||..||||.|.| ||||||.|||| |||||||.||||||...||...  .|| |....||||.|||.|.|||.||...| ..
kfpeefkerkkdkyryryprgEsyedlvqRlepvileLereqenvliiaHqavlrvllaylldksaeelpylkvplhtvikltpvaYgckvellkldv
0051064 Phosphoglycerate mutase-like 223-414 1.3e-48 158.3 In-house 2-231 (241) alignment 
Range on Protein: 223-414
Range on HMM: 2-231/241.0
KPKYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTAN----YLP---YKKLQWKALDELDAGVCDGMTY
..| ..| ||||| .|.|... |  |. |.|.| ..|..| .. ..  |     |..|.|.|..|||.    .|.   ..  ....| |.| |...|.|.
mmkrlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladl.gikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltl

EEIEKEYPEDFKARDNDKYEYRY-------------------------RGGESYRDVVIRLEPVIMELERQ-----ENVLIITHQAVLRCIYAYFMNVPQ
|||....||.. |...|.. .|.                          ||||..||. |..|.. || ..     .|||...|..|.|...||....| 
eeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglpl

EESPWMSIPLHTLIKLEPRAYGTKVTKIKAN
|| .....| .....|| ...|..|. .  |
eellrlnlpngsvtvleldddgkrvvlvlln
0053607 Phosphoglycerate mutase-like 224-408 2.8e-51 165.9 In-house 1-184 (191) alignment 
Range on Protein: 224-408
Range on HMM: 1-184/191.0
PKYIWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPED
.. ..| ||||. .|.|... ||..|.|.| ..|..| .| .|  |     |..|.|.|..|||... ..  ....| |.|.|...|.|.||....|||.
mtrlyLvRHGetewnaegrlqgdvpLtelGreqaralaellael.glkfdavysSpllRarqTaeiiglpvevdprlrEidfgdwegltleelaekypee

FKARDNDKYEYRYRGGESYRDVVIRLEPVIMELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKV
. |. .|.. ||. ||||..||. |..|...|| ...|||...|..|.|...||....| || .....| .....||.. .| ..
laawlrdpldyrppggEsladvaaRvlpaleellaggnvlvVaHggvirallayllglpleellrlnlpngsvtvlelddggwvl
0043909 Phosphoglycerate mutase-like 224-408 4.9e-49 159.3 In-house 2-228 (249) alignment 
Range on Protein: 224-408
Range on HMM: 2-228/249.0
PKYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESAGEINLtVWTSTLKRTQQTANYL----P---YKKLQWKALDELDAGVCDGMTYE
.| ..| ||||. .|.|... |  || |.|.| . |..| ...||    ... |..|.|||..|||...    .   ..  ....| |.| |...|.|..
mkrlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkelgipfda.vysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltka

EIEKEYPEDFKARDN-----------------------------DKYEYRYRGGESYRDVVIRLEPVIMELERQ-----ENVLIITHQAVLRCIYAYFMN
||...|||.. |. .                             |.. .|. ||||..||| |..|...|| ..     .||||..|..|||...||...
eiaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllg

VPQEESPWMSIPLHTLIKLEPRAYGTKV
.. |. .....| .....||. ..|..|
lsledilrlnlpngsitvlelddggkpv
0049178 Phosphoglycerate mutase-like 224-409 4.1e-48 156.4 In-house 3-224 (243) alignment 
Range on Protein: 224-409
Range on HMM: 3-224/243.0
PKYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTANYL----P---YKKLQWKALDELDAGVCDGMTYE
.. ..| ||||. .|.|... |  || |.|.| . |..| .| .|  |     |..|.|||..|||...    .   ..  ....| |.| |...|.|..
mtrlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellael.glkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltka

EIEKEYPEDFKARDNDKYEYRY-----------------------RGGESYRDVVIRLEPVIMELERQ-----ENVLIITHQAVLRCIYAYFMNVPQEES
||...|||.. |. .|.|..|.                        ||||..||. |..|...|| ..     ..||...|..|.|...|.....| || 
eiaakypeelvawwrdpydarppalllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglpleel

PWMSIPLHTLIKLEPRAYGTKVT
... .| .....||   .| ...
lrlnlpngsvtvlelddggwvlv
0036887 Phosphoglycerate mutase-like 224-407 5.1e-48 155.6 In-house 1-191 (202) alignment 
Range on Protein: 224-407
Range on HMM: 1-191/202.0
PKYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKesaGEINLTVWTSTLKRTQQTANYL----PYKKLQWKALDELDAGVCDGMTYEEIE
.. ..| ||||. .|||... |  |. |.|.| ..|..| ....   |     |..|.|.|..|||...    ...  ....| |.| |...|.|.|||.
mtrlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla...glpfdavysSpllRaiqTaeiiaealglpvivdprlrEidfgalegltleeia

KEYPEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELERQ---ENVLIITHQAVLRCIYAYFMNVPQEESPWMS-IPLHTLIKLEPRAYGTK
..|||...|.  |.| .|. ||||..||| |......|| ..   .|||...|..|||...||..... |. ...  .| .....|| ...| .
ekypeelaawlrdpydfrppggEsladvvaRvlaaleellarldggnvlvVsHggvlrallayllglsledllrlrklpngsvtvlelddggwv
0036777 Phosphoglycerate mutase-like 225-415 9.5e-51 165.0 In-house 3-231 (247) alignment 
Range on Protein: 225-415
Range on HMM: 3-231/247.0
KYIWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTAN----YLP---YKKLQWKALDELDAGVCDGMTYEE
| ..| ||||. .|.|... |  |. |.|.| ..||.| .|.||  |     |..|.|.|..|||.    .|.   ..  ....| |.| |...|.|..|
krlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkel.glpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkae

IEKEYPEDFKARDNDKYEYRY-------------------------RGGESYRDVVIRLEPVIMELERQ-----ENVLIITHQAVLRCIYAYFMNVPQEE
|...|||.. |. .|.| ||.                          ||||..||| |..|...|| ..     ||||...|..|||...||..... |.
iaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsled

SPWMSIPLHTLIKLEPRAYGTKVTKIKANI
 ... .| .....|| ...|.... .  | 
ilrlnlpngsitvleldddgklwvleslnd
subfamily_PGAM5_pd Subfamily PGAM5 226-398 4.1e-08 24.6 In-house 3-165 (189) alignment 
Range on Protein: 226-398
Range on HMM: 3-165/189.0
YIWLSRHGEsiYNVEKKIgGDSSLSERGFQYAKKLEQLVKESAGEINlTVWTSTLKRTQQTANYLpYKKLQWKALDELDAGVCDGMTYEEIEKEypEDFK
 . | |||.  |.....   .. |.|.| . |... . .||.  . . .. .||. |...||. .  |.|. .      . ...|  ..   .   . .|
hlilvrhgq..yvlddds.dkkiltelGrrqaeltGkrlkelnlkft.klvastmvravetadii.skqlpdvpkktktellreGaPikpePav..khwk

ARDNDKYEYRYRGGESYRDVVIRLEPvimELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIK
. . . ||   |   ..| .. | .|   | ...   ||..|  |.| .    . .| |    .|.   .. |
pealqfyedgarieaafrkyfhrasp...eqkedsyelivchanvirylvcralqlPpeawlrlslnngsitk
0035570 Phosphoglycerate mutase-like 227-416 1.6e-56 183.4 In-house 2-190 (219) alignment 
Range on Protein: 227-416
Range on HMM: 2-190/219.0
IWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPEDFKA
..| ||||. .|.|... ||. |.||| ..|..| .. ..  |     |..|.|.|..|||... ..  ....| |.|.|...|.|..||...|||...|
lyLvRHGetewnlegrlqgdvpLterGreqaralgealadl.gipfdavysSpllRaiqTaeiiglpveidprLrEidfgdlegltldeiaekypeelaa

RDNDKYEYRYRGGESYRDVVIRLEPVIMELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKVTKIKANIP
. .|.| ||. ||||..||| |..|...|||..||||...|..|.|...||....| || .....| .....||....| |.. .  |. 
wlrdpydyrppggEsladvvaRvlpaleeledgenvlvVsHggvirallayllglpleeilrlnlpngsvtvleldggggkwvlvllndt
0039931 Phosphoglycerate mutase-like 227-412 2.1e-56 182.9 In-house 2-186 (219) alignment 
Range on Protein: 227-412
Range on HMM: 2-186/219.0
IWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPEDFKA
..| ||||. .|||... ||| |.||| ..|..| .. |.  |     |..|.|.|..|||......  ....| |.|.|...|.|.|||...|||.. |
lyLvRHGetewnvegrlqgdspLterGreqaralgerlkdl.glpfdavysSpllRaiqTaeiiglpveidprLrEidfgdlegltleeiaekypeelaa

RDNDKYEYRYRGGESYRDVVIRLEPVIMELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKVTKIK
. .|.|.||. ||||..||| |..|...||...||||...|..|.|...||..... || .....| .....||....| ... . 
wlrdpydyrppggEsladvvaRvlpaleellagenvlvVsHggvirallayllglsleeilrlnlpngsvtvlelddggwvlvlln
0048955 Phosphoglycerate mutase-like 227-404 5.8e-46 149.6 In-house 3-218 (240) alignment 
Range on Protein: 227-404
Range on HMM: 3-218/240.0
IWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESaGEINLTVWTSTLKRTQQTAN----YLP---YKKLQWKALDELDAGVCDGMTYEEIE
..| ||||| .|.|... |  |. |.|.| ..|..| .. ..  |     |..|.|.|..|||.    .|.   ..  .. .| |.| |...|.|..||.
lyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadl.gikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldeia

KEYPEDFKARDNDKYEYRY-------------------------RGGESYRDVVIRLEPVIMELE-----RQENVLIITHQAVLRCIYAYFMNVPQEESP
...||.. .. .|.. .|.                          ||||..||. |..... ||      ...|||...|..|.|...||....| || .
ekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglpleeil

WMSIPLHTLIKLEPRAY
...|| . ...|| . .
rlnipngsvtvlelddg
0050036 Phosphoglycerate mutase-like 227-400 7e-41 131.6 In-house 3-166 (171) alignment 
Range on Protein: 227-400
Range on HMM: 3-166/171.0
IWLSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVkesageINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPEdf
..| ||||...|.|... |  |..|.|.| ..|..| .|           |..|.|.|..|||... ..  ....| |.| |...|.|..||...|||  
lyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell......pfdavysSpllRArqTaelillpvivdprLrErdfGawegltldeiaakype..

kaRDNDKYEYRYRGGESYRDVVIRLEPVIMELErqENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLE
  .. |.. ... ||||..||. |. |.. ||   .|||...|..|.|...|...... || ... .| .... ||
..wlldlldlappggEsladvlaRvlpaleell..gnvlvvaHggvirallalllglsleeilrlelpngsvlvle
His_Phos_1 Histidine phosphatase superfamily (branch 1) 227-374 1.1e-35 115.9 Pfam-A 2-158 (158) alignment 
Range on Protein: 227-374
Range on HMM: 2-158/158.0
IWLSRHGESIYNVEKKIGGDSS--LSERGFQYAKKLEQLVKESAGEINLtVWTSTLKRTQQTANYLPY----KKLQWKALDELDAGVCDGMTYEEIEKEY
..| ||||| .| |... |.|   |.|.| . |..| .  |..  .|.  |.||.|||..|||..|      .  . ..| |.|.|...|...||...|.
lylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpida.vytSplkRaiqTaeilleeldipiikeprLrerdfgeweglpkeevkeef

PEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELE----RQENVLIITHQAVLRCI
||.......||.|.|. .|||..||. |..|...||     ..|||||..|..|||..
peeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvlivsHggvlral
His_Phos_1 Histidine phosphatase superfamily (branch 1) 227-374 1.1e-35 115.9 In-house 2-158 (158) alignment 
Range on Protein: 227-374
Range on HMM: 2-158/158.0
IWLSRHGESIYNVEKKIGGDSS--LSERGFQYAKKLEQLVKESAGEINLtVWTSTLKRTQQTANYLPY----KKLQWKALDELDAGVCDGMTYEEIEKEY
..| ||||| .| |... |.|   |.|.| . |..| .  |..  .|.  |.||.|||..|||..|      .  . ..| |.|.|...|...||...|.
lylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpida.vytSplkRaiqTaeilleeldipiikeprLrerdfgeweglpkeevkeef

PEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELE----RQENVLIITHQAVLRCI
||.......||.|.|. .|||..||. |..|...||     ..|||||..|..|||..
peeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvlivsHggvlral
subfamily_TIGAR_pd Subfamily TIGAR 227-359 1.2e-11 36.7 In-house 3-137 (222) alignment 
Range on Protein: 227-359
Range on HMM: 3-137/222.0
IWLSRHGESIYNVEKKIGGD--SSLSERGFQYAKKLEQLVKesAGEINLtVWTSTLKRTQQTANYLP----YKK----LQWKALDELDAGVCDGMTYEEI
... ||||...| || . |   . |||.|.. ||.. . ..  . .||. . .| |.|..|||..      .||     . | | | . ||  |....|.
livVrhGetefnkekilqgqtdtpLsekGveQakrvakrLs..nekiny.ifsSdllRAkqTaeiilkalkekkreaverdkrLrEreyGvyeGvaldel

EkeypEDFKARDnDKYEYRYRGGESYRDVVIRLEPVIMELERQ
.    |. ||.  .  .    ||||   .  || . . || ..
r....ellkaag.nvpsfvpegGesieqlelrlvaaleelcak
subfamily_PGAM_pd Subfamily PGAM 229-290 9e-11 33.5 In-house 5-67 (248) alignment 
Range on Protein: 229-290
Range on HMM: 5-67/248.0
LSRHGESIYNVEKKIGG--DSSLSERGFQYAKKLEQLVKESAGEInLTVWTSTLKRTQQTANYL
| ||||| .| |.|. |  | .|||.| . |||. ...|..  |.   |.||.|||.|||.. .
llRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlef.divytSvlkRaqqTlevi