Gene GPM1 in Saccharomyces cerevisiae

Synonym: YKL152C, GPM1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PGAM
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP041_AA protein Get Run
ScerP041_AA_0-245 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0036777 Phosphoglycerate mutase-like 1-245 9.4e-74 240.2 In-house 2-246 (247) alignment 
Range on Protein: 1-245
Range on HMM: 2-246/247.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAE
| .|.|||||..|||  ..|.||.|| |...| ..|...|||||| .. .|..|.| | ||||||.|.||  .. ..|| ...||.||.||.|.|..|||
mkrlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkae

TLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDAD
...|..|| .  .|...|..||...   .. .  . || ...   ||. |||| |..|.||......|. | .|..|.. .||..|| |...|.|.|..|
iaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglsled

IAKLNIPTGIPLVFELDENLKPSKPSYYLDPEAAAAGAAAVANQG
|..||.|.|...|.|||.. |. .  .. |..   .|. |||..|
ilrlnlpngsitvleldddgklwvleslndtshlelgleavadfg
0043909 Phosphoglycerate mutase-like 1-226 2.4e-72 235.5 In-house 2-231 (249) alignment 
Range on Protein: 1-226
Range on HMM: 2-231/249.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAE
|..|.|||||..||| ...|.||.|. |...| ..|...||.||| .. .|..|.| | ||||||.|.||  .. ..|| ...||.||..|.|.|..|||
mkrlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkae

TLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYK----YVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGI
...|..|| ..  |||.||.||..... .. .. . .|.    . . . .|..|||| |..|.||......|. | .|..|.| |||..|| |...| |.
iaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgl

SDADIAKLNIPTGIPLVFELDENLKPSKPS
|..|| .||.|.|...|.|||...|| .  
sledilrlnlpngsitvlelddggkpvvvl
0049178 Phosphoglycerate mutase-like 1-220 2.2e-69 225.9 In-house 3-220 (243) alignment 
Range on Protein: 1-220
Range on HMM: 3-220/243.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAE
| .|.|||||..||| .....||.|. |...|...|...||||.| .. .|..|.| | ||||||.|.||  .. ..|| ...||.||..|.|.|. |||
mtrlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkae

TLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPnvLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDAD
. .|..|| .. .|...|..||..  .... .. |.... .|.  ||. |||| |..|.||......|. | .||||.. |||...| |...| |.....
iaakypeelvawwrdpydarppalllldlllplldrlladldl..lpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllglplee

IAKLNIPTGIPLVFELDENL
...||.|.| ..|.|||...
llrlnlpngsvtvlelddgg
0051064 Phosphoglycerate mutase-like 1-228 3.9e-67 218.8 In-house 3-230 (241) alignment 
Range on Protein: 1-228
Range on HMM: 3-230/241.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAE
|..|.|||||.||||  ....|| || |...|...|...||.|..  . .|..|.| | ||||||.|..|  .  ..||   .||.|...|.|.|. ..|
mkrlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltlee

TLKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDAD
. .||.|| .   |...||.||... ......  | ||.......||  |||| |..|.||......|. ||.||.|.. .||...| |...| |.....
iaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggvirallayllglplee

IAKLNIPTGIPLVFELDENLKPSKPSYY
. .||.|.| ..|.|||...|. .  ..
llrlnlpngsvtvleldddgkrvvlvll
0037864 Phosphoglycerate mutase-like 1-221 4.8e-60 194.7 In-house 7-202 (211) alignment 
Range on Protein: 1-221
Range on HMM: 7-202/211.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAE
| .|.|||||..||| .....||.|| |...|...|...||.|.. .. .|..|.| | ||||||.|.||  .. ..|| ...||.||..|.|.|. ..|
mtrlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltlee

TLKKFGEEKFNTYRRSFDVPPPPIdasspfsqkgderykyvdpnvlpetESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDAD
. .|..|| .  .|...|..||.                          |||| |..|.||......|. | .|..|.. .||..|| |...| |.|...
iaekypeelvawlrdpydfrppgg.........................EsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllglslee

IAKLNIPTGIPLVFELDENLK
. .||.|.| ..|.|||....
llrlnlpngsvtvlelddggw
0036887 Phosphoglycerate mutase-like 1-220 1.5e-52 170.4 In-house 1-189 (202) alignment 
Range on Protein: 1-220
Range on HMM: 1-189/202.0
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKekKVYPDVLYTSKLSRAIQTANIALEKADrlwIPVNRSWRLNERHYGDLQGKDKAE
| .|.|||||..||| .....|..|| |...|...|...||.|.  .. .|..|.| | ||||||.|..|  .   .|| . .||.|...|.|.|. ..|
mtrlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltlee

TLKKFGEEKFNTYRRSFDVPPPPIdasspfsqkgderykyvdpnvlpetESLALVIDRLLPYWQDVIAKDllSGKTVMIAAHGNSLRGLVKHLEGISDAD
. .|..|| .  .|...|..||.                          |||| |..|.|.......|.   .|..|.. .||..|| |...| |.|..|
iaekypeelaawlrdpydfrppgg.........................EsladvvaRvlaaleellarl..dggnvlvVsHggvlrallayllglsled

IAKLN-IPTGIPLVFELDENL
. .|. .|.| ..|.|||.. 
llrlrklpngsvtvlelddgg
0053607 Phosphoglycerate mutase-like 1-219 9.3e-52 167.5 In-house 1-180 (191) alignment 
Range on Protein: 1-219
Range on HMM: 1-180/191.0
MPKLVLVRHGQSEWNEKNLFTGwvDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIAlekadrlWIPVNRSWRLNERHYGDLQGKDKAE
| .|.|||||..||| .....|  || |...|...|....|||.|  . .|..|.| | ||.|||.|.       ..|| . .||.|...||..|. ..|
mtrlyLvRHGetewnaegrlqg..dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltlee

TLKKFGEEKFNTYRRSFDVPPppidasspfsqkgderykyvdpnvlPETESLALVIDRLLPYWQDVIAkdllsGKTVMIAAHGNSLRGLVKHLEGISDAD
. .|..|| .. .|...|..|                         |. |||| |..|.||......|     |..|.. |||...| |...| |.....
laekypeelaawlrdpldyrp.........................pggEsladvaaRvlpaleella.....ggnvlvVaHggvirallayllglplee

IAKLNIPTGIPLVFELDEN
. .||.|.| ..|.|||..
llrlnlpngsvtvlelddg
0048955 Phosphoglycerate mutase-like 2-232 9.9e-68 220.7 In-house 1-231 (240) alignment 
Range on Protein: 2-232
Range on HMM: 1-231/240.0
PKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAET
|.|.|||||.|||| .....|| || |...|...|...||.|..  . .|..|.| | ||||||.|..|  .  ..||   .||.||..|.|.|. ..|.
prlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldei

LKKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADI
 .||.|| .   |...||.||...  .....  | ||...|...||. |||| |..|.|.......|. | .||.|.. .||...| |...| |.....|
aekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirallayllglpleei

AKLNIPTGIPLVFELDENLKPSKPSYYLDPE
..||||.| ..|.|||..|.. .  ..||..
lrlnipngsvtvlelddglvslndtshlddl
subfamily_PGAM_pd Subfamily PGAM 3-246 6.9e-109 354.9 In-house 2-248 (248) alignment 
Range on Protein: 3-246
Range on HMM: 2-248/248.0
KLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETL
||||.|||.||.|..| |.||||.||| ||..|| .||..||....  |. |||.|.||.||... ||..|. .|||...|||||||||.|.| .|||..
klvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeldqekiPvektwrLnErhyGaltglnkaeva

KKFGEEKFNTYRRSFDVPPPPIDASSPFSQK--GDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDAD
||.||||....|||.||.|||....... ..   |.||. .....|||.|||. |..||||.....|.|.. .||.|.|.|||||.|.|.|.||||||..
kkyGeekvkiwRRsydvkPPpveedkeyfkeinkdrryeelkeeelPesEslkevveRllpvlneeilkeikegkrvlivahgnsvrallkvlegisdea

IAKLNIPTGIPLVFELDENLKPSKPSYYL-DPEAAAAGAAAVANQGK
|..|..|||||||.|||||||| |....| |.|.... | |||||||
ikeldlptgiplvyeldenlkpvkkkqflgDeesvkkaaeavanqgk
0039931 Phosphoglycerate mutase-like 3-220 3.9e-55 178.8 In-house 1-179 (219) alignment 
Range on Protein: 3-220
Range on HMM: 1-179/219.0
KLVLVRHGQSEWNEKNLFTGwvDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIAlekadrlWIPVNRSWRLNERHYGDLQGKDKAETL
.|.|||||..||| .....|  |. |...|...|...||.||. .. .|..|.| | ||||||.|.       ..|| . .||.|...|||.|....|. 
rlyLvRHGetewnvegrlqg..dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltleeia

KKFGEEKFNTYRRSFDVPPppidasspfsqkgderykyvdpnvlPETESLALVIDRLLPYWQDVIAkdllsGKTVMIAAHGNSLRGLVKHLEGISDADIA
.|..|| .  .|...|..|                         |. |||| |..|.||......|     |..|.. .||...| |...| |.|...|.
ekypeelaawlrdpydyrp.........................pggEsladvvaRvlpaleella.....genvlvVsHggvirallayllglsleeil

KLNIPTGIPLVFELDENL
.||.|.| ..|.|||.. 
rlnlpngsvtvlelddgg
0035570 Phosphoglycerate mutase-like 3-220 9.4e-55 177.6 In-house 1-179 (219) alignment 
Range on Protein: 3-220
Range on HMM: 1-179/219.0
KLVLVRHGQSEWNEKNLFTGwvDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIAlekadrlWIPVNRSWRLNERHYGDLQGKDKAETL
.|.|||||..||| .....|  || |...|...|...||.|.. .. .|..|.| | ||||||.|.       ..|| ...||.|...|||.|....|. 
rlyLvRHGetewnlegrlqg..dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii.......glpveidprLrEidfgdlegltldeia

KKFGEEKFNTYRRSFDVPPppidasspfsqkgderykyvdpnvlPETESLALVIDRLLPYWQDViakdlLSGKTVMIAAHGNSLRGLVKHLEGISDADIA
.|..|| .  .|...|..|                         |. |||| |..|.||.....      .|..|.. .||...| |...| |.....|.
ekypeelaawlrdpydyrp.........................pggEsladvvaRvlpaleel.....edgenvlvVsHggvirallayllglpleeil

KLNIPTGIPLVFELDENL
.||.|.| ..|.|||.. 
rlnlpngsvtvleldggg
0050036 Phosphoglycerate mutase-like 3-218 1.7e-51 166.1 In-house 2-169 (171) alignment 
Range on Protein: 3-218
Range on HMM: 2-169/171.0
KLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLkekkvYPDVLYTSKLSRAIQTANIALekadrlwIPVNRSWRLNERHYGDLQGKDKAETL
.|.|||||..||| ...|.||.|| |...|...|...||||      .|..|.| | ||.|||...|       .|| . .||.||..|...|....|. 
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeia

KKFGEekfntyrrsfdvppppidasspfsqkgdeRYKYVDPNVLPETESLALVIDRLLPYWQDVIakdllsgKTVMIAAHGNSLRGLVKHLEGISDADIA
.|..|                             .....   ..|..|||| |..|.||......       ..|...|||...| |...| |.|...| 
akype.............................wlldlldlappggEsladvlaRvlpaleell.......gnvlvvaHggvirallalllglsleeil

KLNIPTGIPLVFELDE
.|..|.|..||.|||.
rlelpngsvlvleldd
His_Phos_1 Histidine phosphatase superfamily (branch 1) 3-187 3.9e-45 146.6 Pfam-A 1-156 (158) alignment 
Range on Protein: 3-187
Range on HMM: 1-156/158.0
KLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADrlwIPVNRSWRLNERHYGDLQGKDKAETL
.|.|||||.||||... ..|| ||.|..||...| ..|. ||.... .|. |||.|.||||||.| ||. |   ||. ...||.||..|...|..|.|. 
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld...ipiikeprLrerdfgeweglpkeevk

KKFGEEKFNTYRRSFDVPPPpidasspfsqkgderykyvdpnvlpETESLALVIDRLLPYWQDVIAkDLLSGKTVMIAAHGNSLR
..|.||. .  |..... ||                         | |||| |..|. |.....|. .  .|..|.| .||..||
eefpeeyekwkrdkkefrpp.........................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
His_Phos_1 Histidine phosphatase superfamily (branch 1) 3-187 3.9e-45 146.6 In-house 1-156 (158) alignment 
Range on Protein: 3-187
Range on HMM: 1-156/158.0
KLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKADrlwIPVNRSWRLNERHYGDLQGKDKAETL
.|.|||||.||||... ..|| ||.|..||...| ..|. ||.... .|. |||.|.||||||.| ||. |   ||. ...||.||..|...|..|.|. 
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld...ipiikeprLrerdfgeweglpkeevk

KKFGEEKFNTYRRSFDVPPPpidasspfsqkgderykyvdpnvlpETESLALVIDRLLPYWQDVIAkDLLSGKTVMIAAHGNSLR
..|.||. .  |..... ||                         | |||| |..|. |.....|. .  .|..|.| .||..||
eefpeeyekwkrdkkefrpp.........................egesladvyeRvapfleelie.akdkgenvlivsHggvlr
subfamily_TIGAR_pd Subfamily TIGAR 3-101 6.5e-22 70.3 In-house 2-99 (222) alignment 
Range on Protein: 3-101
Range on HMM: 2-99/222.0
KLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVypDVLYTSKLSRAIQTANIALEKADRL-WIPVNRSWRLNERHYGDLQGKDKAET
 |..||||..|.| .....| .|  || || . |.|... |...|.  .  ..| | || |||.| |..       .| |  || || ||...|....| 
ilivVrhGetefnkekilqgqtdtpLsekGveQakrvakrLsneki..nyifsSdllRAkqTaeiilkalkekkreaverdkrLrEreyGvyeGvaldel
subfamily_PFKFB_pd Subfamily PFKFB 3-117 1.8e-16 52.2 In-house 8-113 (198) alignment 
Range on Protein: 3-117
Range on HMM: 8-113/198.0
KLVLVRHGQSEWNEKNLFTGwvDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIAlekadrlWIPVNRSWRLNERHYGDLQGKDKAETL
...|||||.||.| |.  .|  | .|...|.. | .... .||....   ..||.| |.||||..         .|...   |.|.  |...|    |. 
eiylvRhGeseknkkgrigg..dseLterGveyakklakfikeenlkelrvwtselkrtiqTaell.......glpkeqwkaLdeldaGkcdgltyeeik

KKFGEEKFNTYRRSF
.||.||  .  . ..
ekfpeefkerkkdky
subfamily_PGAM5_pd Subfamily PGAM5 3-73 9.5e-08 23.4 In-house 3-68 (189) alignment 
Range on Protein: 3-73
Range on HMM: 3-68/189.0
KLVLVRHGQSEWNEKNlftgwVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKAD
.|.|||||| . ....      .  |...|.. |.. |. ||| ..  . |..| ..||..||.| ... .
hlilvrhgqyvlddds.....dkkiltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskqlp
0048439 Phosphoglycerate mutase-like 5-219 8.3e-06 18.5 In-house 14-327 (391) alignment 
Range on Protein: 5-219
Range on HMM: 14-327/391.0
VLVRHG------------QSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKE----KKVYPDV---------LYTSKLSRAIQTANIALEKA-------
||.|||            .  .|   .. .. .  |...|....   |. | .     . .|.          ...|   |..|.|   |.         
vlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlfpplglt

----------DRLWIP--VNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPPidaS----------SPFSQKGDER---YKYVDPNVLP
          | |. |  .|  ..|.  .  | .    . .|.. .|. .. . |  ..       .            . ..|      . . | . | 
vilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevlnrvlglnlta...edvlslfdlcaketaalgsllklssplcdlftly

ETESLALVIDRLLPYW--------------------------------------------QDVIAKDLLSGKTVMIAAHGNSLRGLVKHLeGISDA----
.|  .    .. ||.|                                            .| .|.  .. | ..  || . .  |   | |. .     
dtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddlvangpsdpklylyfaHdttiaallsaL.glfndtlpl

--DIaklnIPTGIPLVFELDEN
  |.    .| .  ||||| |.
padl....ppyasnlvfElyec
subfamily_STS_pd Subfamily STS 25-77 5.8e-07 21.1 In-house 52-105 (245) alignment 
Range on Protein: 25-77
Range on HMM: 52-105/245.0
DVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQTANIALEKAD-RLWI
|. |.. |.. |   |. | |... ... . |   | ||||.  |.. . .. |
DpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkglgkkiki