Gene GPM3 in Saccharomyces cerevisiae

Synonym: YOL056W, GPM3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily PGAM
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP066_AA protein Get Run
ScerP066_AA_5-296 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0037864 Phosphoglycerate mutase-like 6-276 2.4e-45 146.8 In-house 7-204 (211) alignment 
Range on Protein: 6-276
Range on HMM: 7-204/211.0
TFKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELGLKHtnyvittntnikeelqdtr
. .|...|||..| | |....||.|. |||.|. |||  .......        ... |.| | |..||.. |||.||| .                   
mtrlyLvRHGetewnaegrlqgwldvpLtelGreqaralgealadl.....glpfdavysSpllRaiqTaeiilealglpl...................

fegsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlpesESLCE
    .|| ...||.||..||..|. ...| ..|. | ....|. |.  ||.                                            ||| .
....lpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrppgg...........................................Eslad

VVVRLKPFLNNVVLSTANkiSQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSF
|| |..|.|....  . .  . |  ..|.|| ..|.||..| |.|.|.. .. .||| ..|.||| . . .
vvaRvlpaleellarllk..dgenvlvVsHggvlrallayllglsleellrlnlpngsvtvlelddggwvl
subfamily_PGAM_pd Subfamily PGAM 7-298 1.1e-107 350.9 In-house 1-247 (248) alignment 
Range on Protein: 7-298
Range on HMM: 1-247/248.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQfcdsNNISLpQIGYTSRLIRTQQTMDVILEELglkhtnyvittntnikeelqDTRF
.||..||||.||||.||.||||.||.|.||||..|....|..||    .|... .|.|||.|.|.|||..||||||                    |...
iklvllRhGeselnkenkfcgwvDakLsekGkeeAkkagkalkq....anlef.divytSvlkRaqqTlevileel....................dqek

egsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMvqeendqgsstgydFKEPNRHLKYGpeEKANERLPESESLCEV
   .||..|||||||||||..|..|....|.||.||....||.|..|||.|. . |.              |||.|.. .|   |...|.|||||||.||
...iPvektwrLnErhyGaltglnkaevakkyGeekvkiwRRsydvkPPpveedkey..............fkeinkdrrye..elkeeelPesEslkev

VVRLKPFLNNVVLSTANKisQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYL-DPESAKVNAQMVRDEG
| ||.|.||...|.....  .....||.||.|||.|||||||||||.||..|.|.|||||.|||........|..| |.||.|..|..|...|
veRllpvlneeilkeike..gkrvlivahgnsvrallkvlegisdeaikeldlptgiplvyeldenlkpvkkkqflgDeesvkkaaeavanqg
0043909 Phosphoglycerate mutase-like 7-282 4.9e-52 169.1 In-house 3-234 (249) alignment 
Range on Protein: 7-282
Range on HMM: 3-234/249.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELGlkhtnyvittntnikeelqdtrf
 .|...|||..| | |..|.||.|. |||.|. |||  ....|.         . . |.| | |..||.  ||||||                       
krlyLvRHGetewnaegrfqgwlDspLtelGreqaralgealkel.....gipfdavysSplkRAiqTaeiileelg.......................

EGSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMvqeendqgsstgydFKEPNRHLKYGPEEKANERLPESESLCEV
   .|| ...||.||..||..|. |..|...|..| ... ||.|.  || .. . |.              . | ...... . .. . |.|. ||| .|
ldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlpplleeldel..............llellldyaladldplldrppggEsladv

VVRLKPFLNNVVLSTAnkISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYL
| |..|.|....  .    . .  .||.|| ..|.||. | |.|.||| .. .|||...|.||| . . .|.  .|
vaRvlpaleellarll..kdggnvliVaHggvlrallayllglsledilrlnlpngsitvlelddggkpvvvlvll
0049178 Phosphoglycerate mutase-like 7-277 1.6e-47 154.5 In-house 4-224 (243) alignment 
Range on Protein: 7-277
Range on HMM: 4-224/243.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELGLkhtnyvittntnikeelqdtrf
 .|...|||..| | |....||.|. |||.|. |||. ..|...         ... |.| | |..||.. |||.|||                      
trlyLvRHGetewnaegrlqgwtDspLtelGreqAralgellael.....glkfdavysSplkRaiqTaeiilealgl......................

eGSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNlnlemvqeendqgsstgydfKEPNRHLKYGPEEKANERLPESESLCEV
   .|| ...||.||..||..|. | .| ..|..| ....|. |.  || .                         .. .. .  .  . ||. ||| .|
.pllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppall....................lldlllplldrlladldllpggEsladv

VVRLKPFLNNVVLSTAnkISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFV
. |..|.|.... ..    . .  ..|.|| . |.||. | |...|.. ....||| ..|.||| . ...|
aaRvlpaleellaell..hdgktvlvVaHggvirallalllglpleellrlnlpngsvtvlelddggwvlv
0051064 Phosphoglycerate mutase-like 7-277 3e-47 153.9 In-house 4-226 (241) alignment 
Range on Protein: 7-277
Range on HMM: 4-226/241.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELGLKHtnyvittntnikeelqdtrf
 .|...|||.|| | |....||.|..|||.|. |||  .......        ... |.| | |..||.. |.|.|||..                    
krlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerladl.....gikfdavysSpllRaiqTaeiiaealglpl....................

egsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMvqeendqgsstgydfkepNRHLKYGPEEKANERLPESESLCEV
   .|| ...||.|...||..|. ...| .....|  ...|....  || ..|  ..                    .|..  ..  .. ||  ||| .|
...lpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrppllelldll..................lllldlryagllddllpggEsladv

VVRLKPFLNNVVLSTAnkISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFV
. |..|.|. ..  ..   ...  ..|.|| ..|.||..| |...|.. ....||| ..|.||| |   .|
aaRvlpaleellarll..ldgknvlvVsHggvirallayllglpleellrlnlpngsvtvleldddgkrvv
0036887 Phosphoglycerate mutase-like 7-278 8.9e-44 141.8 In-house 2-194 (202) alignment 
Range on Protein: 7-278
Range on HMM: 2-194/202.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKqfcdsnnISLPQIGYTSRLIRTQQTMDVILEELGLkhtnyvittntnikeelqdtrf
 .|...|||..| | |....|..|. |||.|. |||  .....          . . |.| | |..||.. |.|.|||                      
trlyLvRHGetewnvegrlqgdldvpLtelGreqaralgerla.......glpfdavysSpllRaiqTaeiiaealgl......................

egsmPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlpesESLCEV
    || ...||.|...||..|.....| ..|. | ....|..|.  ||.                                            ||| .|
....pvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrppgg...........................................Esladv

VVRLKPFLNNVVLSTankiSQESCVIVGHGSSVRSLLKVLEGISDEDIKDVD-IPNGIPLVIELDRDNYSFVR
| |. ..|....  .    ...  ..|.|| ..| ||. | |.|.||. ... .||| ..|.||| .....|.
vaRvlaaleellarl....dggnvlvVsHggvlrallayllglsledllrlrklpngsvtvlelddggwvlvl
subfamily_TIGAR_pd Subfamily TIGAR 7-134 4.1e-18 57.9 In-house 1-99 (222) alignment 
Range on Protein: 7-134
Range on HMM: 1-99/222.0
FKLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKqfcdsnNISLPQIgYTSRLIRTQQTMDVILEELGLKHTNYvittntnikeelqdtrf
| | . |||..| | |.|. | .|  |.|||  ||   || ..      |  .  | ..| | |..||...||..|  |. .                  
filivVrhGetefnkekilqgqtdtpLsekGveQakrvakrLs......nekinyi.fsSdllRAkqTaeiilkalkekkrea.................

egsmpVLQTWRLNERHYGAWQGQRKPDI
     | .. || || ||  .|  . ..
.....verdkrLrEreyGvyeGvaldel
0036777 Phosphoglycerate mutase-like 8-296 1.1e-52 171.3 In-house 4-244 (247) alignment 
Range on Protein: 8-296
Range on HMM: 4-244/247.0
KLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELGlkhtnyvittntnikeelqdtrfE
.|...|||..| | |..|.||.|. |||.|. ||.  ..|.|.         . . |.| | |..||.. |||.||                        
rlyLvRHGetewnaegrfqgwlDvpLtelGreqakalgellkel.....glpfdavysSpllRAiqTaeiilealg.......................l

GSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMVQEENDQGSSTGYDfkepnrhlkygpeekaneRLPESESLCEVV
  .|| ...||.||.|||..|. |..|...|..| ... |..|.  || ..| ||...    .     .|                   ||. ||| .||
sllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppllelllelllldllryallpld..................llpggEsladvv

VRLKPFLNNVVLSTAnkISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYLDPESAKVNAQMVRD
 |..|.|....  .    . |  ..|.|| ..|.||..|.|.|.||| .. .|||...|.||| |.. .| ... |..  .. ...|.|
aRvlpaleellarll..kdgenvlvVsHggvlrallayllglsledilrlnlpngsitvleldddgklwvleslndtshlelgleavad
0048955 Phosphoglycerate mutase-like 8-286 3.3e-45 147.1 In-house 2-232 (240) alignment 
Range on Protein: 8-286
Range on HMM: 2-232/240.0
KLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVILEELglkhtnyvittntnikeelqdtrfe
.|...|||.|| | |....||.|..|||.|. |||. ......         ... |.| | |..||.. |.|.|                         
rlyLvRHGesewnaegrlqgwtDvpLtelGreqaralgerLadl.....gikfdlvysSpllRaiqTaeiiaeal.........................

gS---MPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPKVNLNLEMVQEENDQgsstgydfkepnrhlkygPEEKANERLPESESLC
 .   .|| ...||.||..||..|. ...| .....| ....|....  || ..|. |...  .                         .. ||. ||| 
.glpllpvvvdprlrErdfgalegltldeiaekfpeelvlwlrdpldvrppllelldellllldlr..................yalldedllpggEsla

EVVVRLKPFLNNVVLSTANkiSQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRKFYLDPES
.|. |....|. ..    .  ...  ..|.|| ..|.||..| |...|.| ...|||| ..|.|||..  |. .  .||...
dvaaRvlaaleellaralk..pgknvlvVsHggvirallayllglpleeilrlnipngsvtvlelddglvslndtshlddle
0035570 Phosphoglycerate mutase-like 8-279 2.8e-44 143.5 In-house 1-185 (219) alignment 
Range on Protein: 8-279
Range on HMM: 1-185/219.0
KLFILRHGQSELNSENIFCGwiDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVIleelglkhtnyvittntnikeelqdtrfe
.|...|||..| | |....|  |. |||.|. |||. ......         . . |.| | |..||.. |                             
rlyLvRHGetewnlegrlqg..dvpLterGreqaralgealadl.....gipfdavysSpllRaiqTaeii.............................

gSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPpkvnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlPESESLCEVV
  .|| ...||.|...|...|.....| ..|..| ....|..|.  |                                           |. ||| .||
.glpveidprLrEidfgdlegltldeiaekypeelaawlrdpydyrp...........................................pggEsladvv

VRLKPFLNNVvlstankISQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVRK
 |..|.|. .        ..|. ..|.|| ..| ||..| |...|.| ....||| ..|.||| ... .| .
aRvlpaleel.......edgenvlvVsHggvirallayllglpleeilrlnlpngsvtvleldggggkwvlv
0039931 Phosphoglycerate mutase-like 8-278 8.4e-44 141.8 In-house 1-184 (219) alignment 
Range on Protein: 8-278
Range on HMM: 1-184/219.0
KLFILRHGQSELNSENIFCGwiDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVIleelglkhtnyvittntnikeelqdtrfe
.|...|||..| | |....|  |. |||.|. |||  ....|.         . . |.| | |..||.. |                             
rlyLvRHGetewnvegrlqg..dspLterGreqaralgerlkdl.....glpfdavysSpllRaiqTaeii.............................

gSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPpkvnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlPESESLCEVV
  .|| ...||.|...|...|.....| ..|..|  ...|..|.  |                                           |. ||| .||
.glpveidprLrEidfgdlegltleeiaekypeelaawlrdpydyrp...........................................pggEsladvv

VRLKPFLNNVVLstankisQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFVR
 |. |.|. ..        .|. ..|.|| ..| ||. | |.|.|.| ....||| ..|.||| .....|.
aRvlpaleella.......genvlvVsHggvirallayllglsleeilrlnlpngsvtvlelddggwvlvl
His_Phos_1 Histidine phosphatase superfamily (branch 1) 8-242 5.1e-43 139.7 Pfam-A 1-158 (158) alignment 
Range on Protein: 8-242
Range on HMM: 1-158/158.0
KLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQfcdsnNISLPQIGYTSRLIRTQQTMDVILEELGlkhtnyvittntnikeelqdtrfe
.|...|||.||.| |....||.|..|||||. |||. .| .|.     .   ..  |||.| |..||....||||.                        
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkr.....adlpidavytSplkRaiqTaeilleeld........................

gsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPkvnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlpESESLCEVV
  .|. ...||.||..|.|.|..|... .|...|.....|......||                                           | ||| .|.
..ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrpp...........................................egesladvy

VRLKPFLNNVVLstaNKISQESCVIVGHGSSVRSL
 |..|||....    .| ..|. .||.||...|.|
eRvapfleelie...akdkgenvlivsHggvlral
His_Phos_1 Histidine phosphatase superfamily (branch 1) 8-242 5.1e-43 139.7 In-house 1-158 (158) alignment 
Range on Protein: 8-242
Range on HMM: 1-158/158.0
KLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIKQfcdsnNISLPQIGYTSRLIRTQQTMDVILEELGlkhtnyvittntnikeelqdtrfe
.|...|||.||.| |....||.|..|||||. |||. .| .|.     .   ..  |||.| |..||....||||.                        
rlylvRHGesewnkegrlqgwsdvpLtekGreqarelgkkLkr.....adlpidavytSplkRaiqTaeilleeld........................

gsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPPkvnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlpESESLCEVV
  .|. ...||.||..|.|.|..|... .|...|.....|......||                                           | ||| .|.
..ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrpp...........................................egesladvy

VRLKPFLNNVVLstaNKISQESCVIVGHGSSVRSL
 |..|||....    .| ..|. .||.||...|.|
eRvapfleelie...akdkgenvlivsHggvlral
0050036 Phosphoglycerate mutase-like 8-272 1.2e-40 130.9 In-house 2-170 (171) alignment 
Range on Protein: 8-272
Range on HMM: 2-170/171.0
KLFILRHGQSELNSENIFCGWIDAQLTEKGKSQARHSAKLIkqfcdsnnisLPQIGYTSRLIRTQQTMDVILeelglkhtnyvittntnikeelqdtrfe
.|...|||..| | |..|.||.|  |||.|. |||. ..|.           . . |.| |.|..||.. ||                            
rlyLvRHGetewnlegrfqgwtdvpLtelgraqaralgell..........pfdavysSpllRArqTaelil............................

gsMPVLQTWRLNERHYGAWQGQRKPDILKEYGKekymyirrdyngkppkvnlnlemvqeendqgsstgydfkepnrhlkyGPEEKANERLPESESLCEVV
  .|| ...||.||..|||.|... .| ..|..                                                   ... ..|. ||| .|.
..lpvivdprLrErdfGawegltldeiaakype...............................................wlldlldlappggEsladvl

VRLKPFLNNVVlstankisqESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRD
 |. |.|....         .  ..|.|| ..|.||..| |.|.|.| ....|||..||.||| |
aRvlpaleell.........gnvlvvaHggvirallalllglsleeilrlelpngsvlvlelddd
0053607 Phosphoglycerate mutase-like 8-277 8e-40 128.7 In-house 3-185 (191) alignment 
Range on Protein: 8-277
Range on HMM: 3-185/191.0
KLFILRHGQSELNSENIFCGwiDAQLTEKGKSQARHSAKLIKQFcdsnnISLPQIGYTSRLIRTQQTMDVIleelglkhtnyvittntnikeelqdtrfe
.|...|||..| | |....|  |. |||.|. |||  |.|....        . . |.| |.|..||.. |                             
rlyLvRHGetewnaegrlqg..dvpLtelGreqaralaellael.....glkfdavysSpllRarqTaeii.............................

gSMPVLQTWRLNERHYGAWQGQRKPDILKEYGKEKYMYIRRDYNGKPpkvnlnlemvqeendqgsstgydfkepnrhlkygpeekanerlPESESLCEVV
 ..|| ...||.|...|.|.|... .. ..|..| ....|....  |                                           |. ||| .|.
.glpvevdprlrEidfgdwegltleelaekypeelaawlrdpldyrp...........................................pggEsladva

VRLKPFLNNVVLstankisQESCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGIPLVIELDRDNYSFV
 |. |.|....        ... ..|.|| ..| ||. | |...|..  ...||| ..|.||| .....|
aRvlpaleella.......ggnvlvVaHggvirallayllglpleellrlnlpngsvtvlelddggwvlv
subfamily_PFKFB_pd Subfamily PFKFB 8-86 1.5e-10 32.9 In-house 8-77 (198) alignment 
Range on Protein: 8-86
Range on HMM: 8-77/198.0
KLFILRHGQSELNSENIFCGwiDAQLTEKGKSQARHSAKLIKQfcdsNNISlPQIGYTSRLIRTQQTMDVIleelG--LKH
.... |||.|| | ..   |  |..|||.|...|.. || ||.    .|..   . .||.| ||.|| ...    |   ..
eiylvRhGeseknkkgrigg..dseLterGveyakklakfike....enlk.elrvwtselkrtiqTaell....glpkeq
subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 8-79 5.7e-06 16.3 In-house 2-75 (210) alignment 
Range on Protein: 8-79
Range on HMM: 2-75/210.0
KLFILRHGQSELNSE---NIFCGWIDAQLTEKGKSQARHSAKLIKQFCdsNNISLPQ-IGYTSRLIRTQQTMDVIL
|..|.|||.| .| .         .||.|||.|| || . .. ....   ... |      |  |  |....  .|
kvyiirhgestfnkaynekvdpylfdarlteegkkqanelsenvekll..qdvelvisspltraldttkiallkll
0053031 Phosphoglycerate mutase-like 9-281 4.9e-08 25.8 In-house 7-298 (342) alignment 
Range on Protein: 9-281
Range on HMM: 7-298/342.0
LFILRHG----QSELNS---ENIFCGWIDAQLTEKGKSQARHSAKLIKQF----CDSN-NISLPQIgYTSRLIRTQQTMDVILEELGL-KHTNYVIT---
 .. |||    .| ..     . |... . .||..|. ||..  . ...      .|. | .   . ..|   ||.|..  .|. |    .|... .   
ivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyv.rssdvdRtlqSAqaflaGlfppegtpilnpllg

---TNTNIKEELQDTRFEG---SMPVLQTWrlnerHYGAWQGQRKPDILKEYgKEKYMYIRRDYNGKPPK----VNLNLEMVQEENDQGSST----GYDF
    .  . .| .|. . .   . | ....       .|....   ..|..| .| . .. .... .. .    |.   .... |  .| .     ....
wqpipihtepessdalllpnydpcpafdkl.....lkealaseevkellery.lellqklskglgltlsdlldlvsdlydlllyelahglplppwctlft

KEPNRHLkYGPEEKANERLPESES--LCEVVVRLKPFLNNVVLSTANKISQESCVIVGHGSSVRSLLKVLeGISDEDIKdvdiPNGIPLVIELDRDNYSF
 |  ..| |  . .   .|  ..       .. |. .|..    .... ..   . ..| . . .|| .| |. |...     | .  ||.|| .|. ..
leelkal.yaldllyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaL.glfddqlP....pyasnlvfElyedpgey

VRKFY
  ...
yVrvl
0049059 Phosphoglycerate mutase-like 10-139 8.8e-07 21.3 In-house 48-213 (435) alignment 
Range on Protein: 10-139
Range on HMM: 48-213/435.0
FILRHGQ-----------------------------SELNSENIFCGWidAQLTEKGKSQARHSAKLIKQF----CDSNNISLpqigYTSRLIRTQQTMD
 . |||                              |.||. |...|.   .||..|. ||.. .| . .      . ... .    ..|   ||.|.  
vlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplga..geLTplGreqayelGkrlrkrYgfLynpdevyv....rssdvdRtlqSaq

VILEELGLK---------HTNYVITTNTNIKEELQDTRFEGSMPVLQTWRLNERHYGAWQGQRKPDILKEYG
  |. |             .| .. .... .....|| .  | | ....  .   .  ..    ..||| . 
aflaGlfppeilgsqllnplnvyqpvpietvdsdndtlpydscpafdellkellasdeflelflerilkllq
0047369 Phosphoglycerate mutase-like 10-140 7.5e-06 18.5 In-house 49-216 (438) alignment 
Range on Protein: 10-140
Range on HMM: 49-216/438.0
FILRHGQ-----------------------------SELNSENIFCGWidAQLTEKGKSQARHSAKLIKQF---CdsnNISLPQIGYTSRLIRTQQTMDV
 . |||                              | ||. ...||.   |||..|. ||..  | . .    .   | .     ..|   ||.|.   
vlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcga..gqLTplGreqayelGkrlrkrYglL...npedvlyvrssdvdRtlqSAqa

ILEEL-GLKHT---------NYVITTNTNIKEELQDTRFEGSMPVLQTWRLNERHYGAWQGQRKPDILKEYGK
 |  | .  .|         .. | |     . | .. . .| | .. .. .   .  ..    .|||| . |
flaGlfppegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflasdeflelllkdilkrlkk
subfamily_PFKFB_pd Subfamily PFKFB 190-274 9.7e-07 20.4 In-house 110-186 (198) alignment 
Range on Protein: 190-274
Range on HMM: 110-186/198.0
EEKANERLPESESLCEVVVRLKPFLNNVvlstaNKISQEsCVIVGHGSSVRSLLKVLEGISDEDIKDVDIPNGipLVIELDRDNY
..|   | |..||  ..| ||.| . ..     ......  .|. | . .| ||. |   | |... ...|     ||.|   .|
kdkyryryprgEsyedlvqRlepvileL.....ereqen.vliiaHqavlrvllaylldksaeelpylkvplh..tvikltpvaY