Gene LTP1 in Saccharomyces cerevisiae

Synonym: YPR073C, LTP1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family LMWPTP
Subfamily LMWPTP
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP074_AA protein Get Run
ScerP074_AA_5-159 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0046251 Phosphotyrosine protein phosphatases I 6-158 8.1e-52 165.7 In-house 4-156 (159) alignment 
Range on Protein: 6-158
Range on HMM: 4-156/159.0
PKISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKI
 |..| |.|.|| ||||||||...| .|.|.|....  .|| |||..||||.||.|.|...|..|....|...|..  .|.|.|.|..||.||...|...
mkkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsalhvgeppdpravavlkelgidlshrarqlteedfeefdlilamddsnlrdllrl

QPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLK
 |.....||.|.... .. ... . ..||.||....||. ...|. . ...|.
apgdargkvllllefagllellhwdvpDPyyggleaFeevldlieeavealle
0053360 Phosphotyrosine protein phosphatases I 6-158 3.5e-46 147.2 In-house 4-154 (157) alignment 
Range on Protein: 6-158
Range on HMM: 4-154/157.0
PKISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFnKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKI
 ...| |.|.|| ||||||||...| .|.|.|..||  .|| |||..|||...|.|.|......|....|...|..  ...|.|.|. ||.||...| ..
kmkkvLfvCtgNicRSpmAeallrhlleeaglgdrf.evdSaGtsalhvggpvdpravevlaelgidlshrarqlteedleefdliltmddsnleellpl

QPE--GSKAKVCLFGDWNtndGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLK
 |.  ..|.|| |....    |..   ..||.||....||. ...|. . ...|.
fpglleakgkvllllefa...gllhwdvpDPyyggleafelvldlieeavealle
0048765 Phosphotyrosine protein phosphatases I 7-158 9.7e-46 145.7 In-house 2-151 (154) alignment 
Range on Protein: 7-158
Range on HMM: 2-151/154.0
KISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFnKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQ
...| |.|.|| ||||||||...| .|.|.|..|.  .|| |||.|||||..|.|.|......|....|...|..  ...|.|.|. ||.||...| .. 
mkkvLfvCtgNicRSpmAeallrhlleeaglgdrv.evdSaGtsayhvgepvdpravevlaelgidlshrarqlteedleefdliltmddsnleellplf

PE--GSKAKVCLFGDWNtndGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLK
|.  ..|.|| |....    |..   ..||.||....||. ...|. . ...|.
pglleakgkvllllefa...gllhwdvpDPyyggleafeevldlieeavealle
0042188 Phosphotyrosine protein phosphatases I 7-159 6e-42 133.3 In-house 4-142 (146) alignment 
Range on Protein: 7-159
Range on HMM: 4-142/146.0
KISVAFICLGNFCRSPMAEAIFKHEVekanleNRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKIN-HKGKQIKTKHFDEYDYIIGMDESNINNLKKI
|..| |.|.|| ||||||||...| .      ...  .|| |||.|||||..|.|.|......|..|. |  .|... ...|.|... ||.||...| ..
kkkvlfvCtgNicRSpmAeallrhll......gdrvevdSAGtsayhvgepvdpravevlaelgidisghrarqlteedleefDlvltmddsnlrdllpl

QPEGSKAKVCLFGDWNtndgtvqtIIEDPWYGDiQDFEYNFKQITYFSKQFLKK
 |. .|.||.|....          ..||.||. ..||. ...|  . |..|..
fpgaakgkvllllefw........dvpDPyygg.eafeevldlieeavkallel
0047572 Phosphotyrosine protein phosphatases I 7-158 1.2e-29 93.1 In-house 2-129 (130) alignment 
Range on Protein: 7-158
Range on HMM: 2-129/130.0
KISVAFICLGNFCRSPMAEAIFKHEVekanleNRFNKIDSFGTSnyhvGESPDHRTVSICKQHGVKI-NHKGKQIKTKHFDEYDYIIGMDESNINNLKKI
|..| |.|.|| ||||||||...| .      .   ...| ||.    |...|.|.| .....|..| .|. ||..  ...|.|..| ||.|....|  .
kkkvlfvCtgNscRSpmAeallrhll......gdrvevySAGte....gsgvdpravevlaelgidisghrskqldelllpefdlvitmddsalealpll

QPEGSKAKVclfgdwntndgtvqtIIEDPWYGDIQDFEYNFKQITYFSKQFLK
 |.   . .                |.||..|....|.  ...|  . ...|.
apaalrlhw...............dipDPygggleafrevrdlierrvlalle
subfamily_LMWPTP_pd Subfamily LMWPTP 8-159 1.1e-66 213.3 In-house 2-151 (152) alignment 
Range on Protein: 8-159
Range on HMM: 2-151/152.0
ISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFnKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQP
 .| |.||||.||||.|||.... |||..|.... |.||...|.||||..||.|..||.|.||.|..|...||....|.|.|||..|||||...|||...
kkvlfvClGniCrspiaEavlrklvekkglkedw.kvdsaaissyhvGkepdkRalsilkkhglksshrarqitkedfsefdyilamDesnlkelkklak

--EGSKAKVCLFGDWNTNDgtvQTIIEDPWYGDIQDFEYNFKQITYFSKQFLKK
  ..|||||.|.|......   ..|||||.||| .|||...|||....|.||||
ekkeskakvlllgeydkkg...keiiedpyygdekdFeavykqikecckaflkk
0047618 Phosphotyrosine protein phosphatases I 8-158 5.1e-32 100.9 In-house 2-134 (137) alignment 
Range on Protein: 8-158
Range on HMM: 2-134/137.0
ISVAFICLGNFCRSPMAEAIFKHEVEKAnlenrfNKIDSFGTSNYHvgesPDHRTVSICKQHGVKIN-HKGKQIKTKHFDEYDYIIGMDESNINNLKKIQ
..| |.|.|| ||||||||...| ...        ..|| ||....    .|.|.| .....|..|. |. ||.   ...|.|... ||.|....|  . 
kkvlfvCtgNicRSpmAeallrhllgdr......vevdSAGtepag....vdpravevlaelgidisghrskqldeldlpefdlvltmddsalealplla

PEGSKAKVclfgdwntndgtvqtIIEDPWYGD------IQDFEYNFKQITYFSKQFLK
|.   ...                ..||.||.      ...||. ...|. . ...|.
paalrlhw...............dvpDPyygggteeekleafervldlieervealle
LMWPc_SSU72_ArsC 9-149 5.1e-43 137.0 In-house 2-126 (126) alignment 
Range on Protein: 9-149
Range on HMM: 2-126/126.0
SVAFICLGNFCRSPMAEAIFKHEVEKanlenrFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPE
.|.|.|||| ||||||||..|. |.|        ...|.||.....|.|.|.|.|...|..|....|| .|.......|.|.|..|||.| .....  ||
kvlfvClgNicRSpmAeavlkkavkk......glnvsSaGtgaavpgksidsravellkengielkhkprqlqeedlkefdliltmdernkdevlellpe

GSKAKVCLFgdwntndgtvQTIIEDPWYGDIQDFEYNFKQI
  ..|| |.          .. ..||..|....||. ...|
ratkkvhll..........nldvkDpyegaesgfeevldli
LMWPc_SSU72 9-158 1.3e-36 116.5 In-house 2-136 (137) alignment 
Range on Protein: 9-158
Range on HMM: 2-136/137.0
SVAFICLGNFCRSPMAEAIFKHEVEkanlenrFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPE
.|.|.|..|..||..|||..|...|         ...|.||.....|.|.|.......|..|..|... ...........|..| ..|...... .  ||
kvlfVCasNinRSmeAeallkeale.......glevkSaGtgslvpgpsidkpaeelykenGlsikeapeklqeeelekfDlvitleervfdavvedlpe

G--SKAKVCLFgdwntndgtvQTIIEDPWYGDIQDFEYNFKQITYFSKQFLK
   .|.||...          .  |.||....|..|.. ...|.   |..|.
rselkrkvhvi..........nvdikDpheeaiegfkaildlieervkella
0051181 Phosphotyrosine protein phosphatases I 9-158 3e-33 104.7 In-house 1-123 (124) alignment 
Range on Protein: 9-158
Range on HMM: 1-123/124.0
SVAFICLGNFCRSPMAEAIFKHEVEKanlenrfNKIDSFGTsnyHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPe
.| |.|.|| ||||||||...| ...        ..|| ||   |.|...|.|.| .....|...... ||..  ...|.|... ||.||...|  ..| 
kvlfvCtgNicRSpmAeallrhllgd.......vevdSAGt...hpggpvdpravevlaelgidlslrskqldeldleefdlvltmddsnlcpllplap.

gskakvcLFGDWntndgtvqtIIEDPWYGDIQDFEYNFKQITYFSKQFLK
       |. .|          ..||.||....||. ...|  . ...|.
.......lllhw.........dvpDPyyggleefeevldlieervealle
LMWPc Low molecular weight phosphotyrosine protein phosphatase 10-157 6.4e-49 156.4 Pfam-A 1-138 (138) alignment 
Range on Protein: 10-157
Range on HMM: 1-138/138.0
VAFICLGNFCRSPMAEAIFKHEVEKAnLENRFnKIDSFGTSNYhVGESPDHRTVSICKQHGVKIN-HKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPE
|.|.|.||.||||||||......||| |.... ..|| ||... ||||.|.|.|...|..|..|. | ..|.......|.|.|. .||.....|....||
vlfvCtgNicRSpmAeallralleka.lgdkv.evdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape

GSKAKVCLFGDwntndgtvQTIIEDPWYGDIQDFEYNFKQITYFSKQFL
 ..|||.|.|.        |. |.||.......||  ...|. ..|..|
kkeakvvllge........qwdipDPygkeeeefeevrdeieervkkll
LMWPc Low molecular weight phosphotyrosine protein phosphatase 10-157 6.4e-49 156.4 In-house 1-138 (138) alignment 
Range on Protein: 10-157
Range on HMM: 1-138/138.0
VAFICLGNFCRSPMAEAIFKHEVEKAnLENRFnKIDSFGTSNYhVGESPDHRTVSICKQHGVKIN-HKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPE
|.|.|.||.||||||||......||| |.... ..|| ||... ||||.|.|.|...|..|..|. | ..|.......|.|.|. .||.....|....||
vlfvCtgNicRSpmAeallralleka.lgdkv.evdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape

GSKAKVCLFGDwntndgtvQTIIEDPWYGDIQDFEYNFKQITYFSKQFL
 ..|||.|.|.        |. |.||.......||  ...|. ..|..|
kkeakvvllge........qwdipDPygkeeeefeevrdeieervkkll