Gene STS in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily STS
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP170_AA protein Get Run
SpurP170_AA_386-628 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
UBA UBA/TS-N domain 29-59 5.6e-07 17.8 Pfam-A 8-37 (37) alignment
Range on Protein: 29-59
Range on HMM: 8-37/37.0
LLMSMGFPKHRVEKAAAATGHqDIQLASDWL
 |. |||..... ||  ||.  ... | ..|
qLreMGfsreeakkALratnn.nverAveyL

2_5_RNA_ligase2 2'-5' RNA ligase superfamily 106-214 3.7e-06 15.4 Pfam-A 21-127 (153) alignment
Range on Protein: 106-214
Range on HMM: 21-127/153.0
AHSLLPHVTLCSFITCPDSKctaltDAFQEVIDRWQ--TKAPEvLTLDFYSS---TNFiGLFLEDEHAEYLRKVMADFSVEAASRAGVKVEPHKKQLHLT
..   ||.||.   . |..      ....|.. |.   |.. | ..|| ...    .   ..||..  | |... |.   . .    .. . .. . |||
yprwppHiTLlypfvepedl.....qdlaellsrlaaetepfe.vrldgvgvFehkks.vvylevspseslsaLraallealpeaglkedstgeftPHlT

LAYQFNPTHQEPLV
.|.. ..| .. |.
iaqsedstsakell

LigT_PEase LigT like Phosphoesterase 166-212 8.2e-06 14.2 Pfam-A 6-52 (87) alignment
Range on Protein: 166-212
Range on HMM: 6-52/87.0
EHAEYLRKVMADFSvEAASRAGVKVEpHKKQLHLTLAYQFNPThqE----P
| || |... |..  .|....|.|.. .. ..|.|||  .. .  |     
eiaeelarlaaele.ralaklglkpv.rpfnpHiTLaflgevd..eekvpe

SH3_1 SH3 domain 246-296 3.6e-07 18.8 Pfam-A 1-47 (48) alignment
Range on Protein: 246-296
Range on HMM: 1-47/48.0
RVLYGHTPRVPDELELIPDDFVYMSATELDknsdGWFKGTSHKTGCEGMFP
..||  ..| .||| . ..| ..  . . |    ||.|| ...|| ||..|
iAlYDYearesdELsfkkGDviivleksed....gWwkgrlkgtgkeGliP

SH3_9 Variant SH3 domain 247-301 1e-14 43.1 Pfam-A 1-49 (49) alignment
Range on Protein: 247-301
Range on HMM: 1-49/49.0
VLYGHTPRVPDELELIPDDFVYMSaTEldkNSDGWFKGTShkTGCEGMFPGNYTE
.|| ..|. .|||.| ..|.....  |    .|||. |..  ||. | .| ||.|
AlydyepkdddELslskGdvitvl.ee...tedgWllGel..tGrtGlvPanyVe

0037864 Phosphoglycerate mutase-like 387-620 2.8e-28 91.2 In-house 6-199 (211) alignment
Range on Protein: 387-620
Range on HMM: 6-199/211.0
QPRRLFIIRHGERVDVTFGEQWlihcfdqqgkyqrknlnmpkrvpqrpggGqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
...||...||||... . |  .                            |     |.|.|| |. |||..||||. .|......|.|| ||. |||...
lmtrlyLvRHGetewnaegrlq............................g...wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeii

LQGLEAPdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKEC-SDDGDILLVGHASTLDS
|..|  |  ... || .| |.  .   ||..    ..       .  ..     |    . |. .....| .....|.|... .|....|.|.|. .| .
lealglp.llpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrpp....ggEsladvvaRvlpaleellarllkdgenvlvVsHggvlra

SSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYA
  . | |||   ....     ..|..... ||   
llayllglsleellrl.....nlpngsvtvleldd

0036777 Phosphoglycerate mutase-like 388-627 3.8e-32 104.2 In-house 2-226 (247) alignment
Range on Protein: 388-627
Range on HMM: 2-226/247.0
PRRLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrPGGGQDFkKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...|||| .. .                               |  |.   |.|.|| |. ||. .||.|| .|... ..|.|| ||. |||...|
mkrlyLvRHGetewna..............................egrfqgw.lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiil

QGLEAPdAVKICVDTALFEW---------------------LAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVREVLK
..|. .  ... || .| |.                      ||. . .. .  . || .  |..|| .   |.   | . |. .....| .....|.| 
ealgls.llpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleella

EC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDL
..  |....|.|.|. .| .  . | |||   ....     ..|...|. ||  ..  .| |
rllkdgenvlvVsHggvlrallayllglsledilrl.....nlpngsitvleldddgklwvl

0051064 Phosphoglycerate mutase-like 388-628 3.6e-31 101.3 In-house 3-228 (241) alignment
Range on Protein: 388-628
Range on HMM: 3-228/241.0
PRRLFIIRHGERVDVTFGEQWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...||||... . |  .                                  |.|.|| |. |||..||.|...|||....|.|| ||. |||....
mkrlyLvRHGesewnaegrlqg...............................wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiia

QGLEAPdAVKICVDTALFEWLAWCKGGLPKWLS----PAELATFGLNIDLSYKEKLTPSDL-----------------NQKENCQAYYKRSENFVREVLK
..|  |  ... || .| |.   .  ||...      | ||. .  .    .   |...||                    |. .....| .....|.| 
ealglp.llpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleella

E-CSDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDLV
.   |....|.|.|. .. .  . | ||.   .. .     ..|..... ||  .... . ||
rllldgknvlvVsHggvirallayllglpleellrl.....nlpngsvtvleldddgkrvvlv

0043909 Phosphoglycerate mutase-like 388-621 2.3e-30 98.2 In-house 2-224 (249) alignment
Range on Protein: 388-621
Range on HMM: 2-224/249.0
PRRLFIIRHGERVDVTFGEQwlihcfdqqgkyqrknlnmpkrvpqrpgggQDfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVL
..||...|||| .. . |                                |.   |||.|| |. |||..|||||..||.....|.|| .|. |||...|
mkrlyLvRHGetewnaegrf..............................qg.wlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiil

QGLEAPDaVKICVDTALFEW------------------------LAWCKGGLPKWLSPAELATFGLNIDLSYKE-KLTPSDLNQKENCQAYYKRSENFVR
..|. .  ... || .| |.                        |..  . || .|..  .  . |..|. ...  .    ... |. .....| .....
eelgldk.lpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpale

EVLKEC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAE
|.|...  |.|..|.|.|. .| .  . | ||| . ....     ..|...|. ||  ..
ellarllkdggnvliVaHggvlrallayllglsledilrl.....nlpngsitvlelddg

0036887 Phosphoglycerate mutase-like 388-618 8.5e-27 86.5 In-house 1-185 (202) alignment
Range on Protein: 388-618
Range on HMM: 1-185/202.0
PRRLFIIRHGERVDVTFGEQW--LihcfdqqgkyqrknlnmpkrvpqrpgggqdfkkDSPITEIGVYQARMTGEALKaaGIKISYCYASPSLRCSQTAHA
..||...||||... . |     |                                 |.|.|| |. |||..||.|.  |... ..|.|| ||. |||..
mtrlyLvRHGetewnvegrlqgdl.................................dvpLtelGreqaralgerla..glpfdavysSpllRaiqTaei

VLQGLEapdaVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECsDDGDILLVGHASTLDS
....|.    ....|| .| |.  ..  ||..    ..   .   .  ..     |    . |. .....| .....|.|... |.|..|.|.|. .|  
iaealg....lpvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrpp....ggEsladvvaRvlaaleellarl.dggnvlvVsHggvlra

SSRCLQGLSARPAMEFSrivqKVPYCGIIMLEE
  . | |||   .. .     |.|..... || 
llayllglsledllrlr....klpngsvtvlel

0049178 Phosphoglycerate mutase-like 388-618 1.5e-25 82.7 In-house 3-216 (243) alignment
Range on Protein: 388-618
Range on HMM: 3-216/243.0
PRRLFIIRHGERVD----VTFGeqwlihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTA
..||...|||| .     .  |                                     ||| || |. ||| .||.|...|.|. ..|.|| .|. |||
mtrlyLvRHGetewnaegrlqg...................................wtDspLtelGreqAralgellaelglkfdavysSplkRaiqTa

HAVLQGLEAPDaVKICVDTALFEW---------------------LAWCKGGLPKWLSPaeLATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVR
...|..|  |  ... || .| |.                      ||  . .  .  .  | ...| ..| .   .    | . |. .....| .....
eiilealglpl.lpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa..lllldlllplldrlladldllpggEsladvaaRvlpale

EVLKEC-SDDGDILLVGHASTLDSSSRCLQGLSARPAMEFSrivqkVPYCGIIMLEE
|.|.|.  |....|.|.|  .. .  . | ||.   .. .      .|..... || 
ellaellhdgktvlvVaHggvirallalllglpleellrln.....lpngsvtvlel

subfamily_STS_pd Subfamily STS 389-637 1.1e-94 308.4 In-house 1-244 (245) alignment
Range on Protein: 389-637
Range on HMM: 1-244/245.0
RRLFIIRHGERVDVTFGEqWLIhCFDqQGKYQRKNLNMPKRVPQRPGGGQDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQ
|...|.|||||||..||. ||  .|| .|||.||.||.||..|.||.| .|.|.|.|.||.||.||...|.||  |||||.....|||||| |||.|.|.
rtiyivRhgeRvdevfgk.Wlk.sfd.egkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailk

GLEapDAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTPSDLNQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLDSSSR
||.  ...||.|...|.|||..... .|..||| ||..|...||..||. |..|.|..||.....|.|....|.|.......||.||.|.||.|||..||
glg..kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslselkskeseeelyeRikkvvkeiiekvpedgniliVahaatldalsr

CLQGLSARPAMEFSRIVQKVPYCGIIMLEEYAEFSIWDLVAPIIPTLTH
.|.|||.| .......|.|.|||.. .|||..| . |.|... |. |..
qllglspresedlkklvikspycslakleenkeerkwkltdsgilsllk

0048955 Phosphoglycerate mutase-like 390-628 1.2e-30 99.5 In-house 2-225 (240) alignment
Range on Protein: 390-628
Range on HMM: 2-225/240.0
RLFIIRHGERVDVTFGEQWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQG
||...||||... ..|  .                                  |.|.|| |. |||..||.|...|||....|.|| ||. |||......
rlyLvRHGesewnaegrlqg...............................wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaea

LEAPDaVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKE---------------------KLTPSDLNQKENCQAYYKRSENFVREVLKEC
|  |  ....|| .| |.  ..  ||..    ...  .   .  .                        .|... |   |. .....| .....|.|...
lglpl.lpvvvdprlrErdfgalegltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellara

S-DDGDILLVGHASTLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYAEFSIWDLV
  .....|.|.|. .. .  . | ||. . ....     ..|..... || . ..  .. .
lkpgknvlvVsHggvirallayllglpleeilrl.....nipngsvtvlelddglvslndt

His_Phos_1 Histidine phosphatase superfamily (branch 1) 390-585 1.2e-27 89.8 Pfam-A 1-157 (158) alignment
Range on Protein: 390-585
Range on HMM: 1-157/158.0
RLFIIRHGERVdvtfgeqwlihcfdqqgkyqrknlnmpK----RvpqrPGGGQDfkkdSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHA
||...||||..                                |      | .|    .|.|| |  ||| .|..||.|...|. .|.||..|. |||..
rlylvRHGese...........................wnkegr....lqgwsd....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei

VLQGLEapdaVKICVDTALFEWLA-WCKgGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLD
.|..|.    ..|. . .| |. .  .. ||||.  ..|.     ...  .||   |    ..|. ...|.| ..|..|.... ......|.|.|...|.
lleeld....ipiikeprLrerdfgewe.glpkeevkeefpeeyekwkrdkkefrpp....egesladvyeRvapfleelieakdkgenvlivsHggvlr

S
.
a

His_Phos_1 Histidine phosphatase superfamily (branch 1) 390-585 1.2e-27 89.8 In-house 1-157 (158) alignment
Range on Protein: 390-585
Range on HMM: 1-157/158.0
RLFIIRHGERVdvtfgeqwlihcfdqqgkyqrknlnmpK----RvpqrPGGGQDfkkdSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHA
||...||||..                                |      | .|    .|.|| |  ||| .|..||.|...|. .|.||..|. |||..
rlylvRHGese...........................wnkegr....lqgwsd....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei

VLQGLEapdaVKICVDTALFEWLA-WCKgGLPKWLSPAELATFGLNIDLSYKEKLTPsdlnQKENCQAYYKRSENFVREVLKECSDDGDILLVGHASTLD
.|..|.    ..|. . .| |. .  .. ||||.  ..|.     ...  .||   |    ..|. ...|.| ..|..|.... ......|.|.|...|.
lleeld....ipiikeprLrerdfgewe.glpkeevkeefpeeyekwkrdkkefrpp....egesladvyeRvapfleelieakdkgenvlivsHggvlr

S
.
a

0035570 Phosphoglycerate mutase-like 390-622 4e-26 84.3 In-house 1-179 (219) alignment
Range on Protein: 390-622
Range on HMM: 1-179/219.0
RLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrP---GGgqdfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
||...||||... .                              .    |      |.|.|| |. |||..||||.. ||.. ..|.|| ||. |||...
rlyLvRHGetewnl..............................egrlqg......dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii

lqgleapdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLSYKEKLTpsdlNQKENCQAYYKRSENFVREVlkecSDDGDILLVGHASTLDSS
         .....| .| |. .    ||..    ..       .  .          .. |. .....| .....|.     |....|.|.|. ..   
........glpveidprLrEidfgdlegltldeiaekypeelaawlrdpydyrp....pggEsladvvaRvlpaleel....edgenvlvVsHggviral

SRCLQGLSARPAMEFSrivqkVPYCGIIMLEEYAEF
 . | ||..  .. ..     .|..... ||  .. 
layllglpleeilrln.....lpngsvtvleldggg

0039931 Phosphoglycerate mutase-like 390-620 1.9e-24 78.7 In-house 1-177 (219) alignment
Range on Protein: 390-620
Range on HMM: 1-177/219.0
RLFIIRHGERVDVTfgeqwlihcfdqqgkyqrknlnmpkrvpqrP---GGgqdfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAV
||...|||| .. .                              .    |      |||.|| |. ||| .||.||  |... ..|.|| ||. |||...
rlyLvRHGetewnv..............................egrlqg......dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii

lqgleapdAVKICVDTALFEWLAWCKGGLPKWLSPAELATFGLNIDLS-----YkekltpsdlNQKENCQAYYKRSENFVREVLKecsdDGDILLVGHAS
         .....| .| |. .    ||..    ..       .  .     .         .. |. .....| .....|.|.    ....|.|.|. 
........glpveidprLrEidfgdlegltleeiaekypeelaawlrdpydyrp.........pggEsladvvaRvlpaleella....genvlvVsHgg

TLDSSSRCLQGLSARPAMEFsrivqKVPYCGIIMLEEYA
..    . | |||   .. .     ..|..... || ..
virallayllglsleeilrl.....nlpngsvtvleldd

subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 391-617 1.1e-41 133.7 In-house 2-210 (229) alignment
Range on Protein: 391-617
Range on HMM: 2-210/229.0
LFIIRHGERVDVTFGEqWlIHCFDQQGKYQRKNLNMPKRVPQRPgggQDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGL
...||..||||  ||. | |. .| ..||.  ..|.|| .|.|.   . .| |.|.|||| ......| ||. .||..|  . || ||. |||...|.||
vvvirsaervdevfgk.W.iksadletkyrpldinvPkelpkra...ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkgl

EApDAVKICVDTALFEwlawCKGGLPKWLSPAELATFGLNIDLSYKEKltpSDLNQKENCQAYYKRSENFVREVLKECSdDGDILLVGHASTLDSSSRCl
     ..| |. .|.|     .   ...|.| ..  .|  .|  ||      .| ..|. . ...|........|...  .. ||.| .. .|. . |  
Gl.kraaisvePgLle....yrkarevllppkafkklgypvdekYkPl...kelsmaeslsdfvariqaafkkllskve.qklilvvadnvsleltrre.

qglSARPAMEFSRIVQKVPYCGIIMLE
     . . ... ...| |.. . ...
...dvesvddllvllkktpalsvvivn

0053031 Phosphoglycerate mutase-like 391-503 3.1e-11 36.3 In-house 7-116 (342) alignment
Range on Protein: 391-503
Range on HMM: 7-116/342.0
LFIIRHGERV-----DVTFGEQWLIhcfdqqgkyqrknlnmpkrvpqrpgggqdfKKD-SPITEIGVYQARMTGEALKAA---------GIKISYCYASP
 ...|||.|      ....  .| .                              . . .. |. |..||...|..|.             .. | ..|.
ivlvRHGaRtPlskgpldplnewfy..............................pcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssd

SLRCSQTAHAVLQGLEAPDAVKI------------CVDTA
. |. |.| |.|.||  |.  .|             .  .
vdRtlqSAqaflaGlfppegtpilnpllgwqpipihtepe

0047369 Phosphoglycerate mutase-like 392-521 2.2e-11 36.7 In-house 49-164 (438) alignment
Range on Protein: 392-521
Range on HMM: 49-164/438.0
FIIRHGERVD----VTfGEQWLIHCFDQQGKYQRKNLNMPKRVPQRPGGGQdfkkdspITEIGVYQARMTGEALKAA----GIKIS-YCYASPSLRCSQT
 ..|||.|         ....|. .... . | . .|.. ....   | ||        |. |..||.. |. | .       .   | ..|.. |. |.
vlfRHGaRtPtksklk.kleplwellenattypsgplsflndwlgpcgagq.......LTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqS

AHAVLQGLEAPDAVKICVDTALFewlawckgglpkwlsP
| |.|.||  |.  ..  .  .                |
AqaflaGlfppegtgelapilwq...............p

0049059 Phosphoglycerate mutase-like 392-507 4e-11 35.6 In-house 48-152 (435) alignment
Range on Protein: 392-507
Range on HMM: 48-152/435.0
FIIRHGERV---DVTFGEQWLIHCFDQQGKYQRKNLNMPKRVPQRPGGGQdfkkdspITEIGVYQARMTGEALKA-----AGIKISYCYASPSLRCSQTA
 ..|||.|     .  . . |.... .   | . .|.. . ..   | |.        |. |..||...|. | .        .  | ..|.. |. |.|
vlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgage.......LTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSa

HAVLQGLEAPDavkicvdtalfeW
 |.|.||  |.            .
qaflaGlfppe............i

0048946 Phosphoglycerate mutase-like 392-566 2.3e-10 33.0 In-house 46-200 (447) alignment
Range on Protein: 392-566
Range on HMM: 46-200/447.0
FIIRHGERV---DVTFGEQWLIHCFDQQGK-YQRKNLNMPKRVPQRPGGGQDFK--KdSPITEIGVYQARMTGEALKAA------GIKISYCYASPSLRC
 ..|||.|    ....| ..|. ......  . ...|..... .  .. .  .     .  |. | .|... |..|.          .  | ..|.. |.
vlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcgl.gqLTplGreqlyelGkrlrkrYlgllpnpseiyvrssdvdRt

SQTAHAVLQGLEAPDavkicvdtalfewlawckgglpkwlspaelatfglnidL--SY--------KEKLTPSDLNqkeNCQAYYKRSENFVREVLK
 |.| |.|.||  |.                                      .  .|        ..   .. |.   .|.|...   ... | ||
lqSaqaflaGlfppe......................................pplgyqpipihtvpssndnlllp...sCpafkellkkelaeelk

0046349 Phosphoglycerate mutase-like 392-566 5.6e-10 32.1 In-house 12-170 (409) alignment
Range on Protein: 392-566
Range on HMM: 12-170/409.0
FIIRHGERVDVTFgeqwlihcF-----------DqqgkyqrknlnmpkrvpqrpgggqDFKKD-SPITEIGVYQARMTGEALKA----AGI---------
...|||.|  .          .                                     .. . .. |. |..||...|..|..     |.         
vlfRHGaRtPtkk........lsflpnwpginwt........................ngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynp

KISYCYASPSLRCSQTAHAVLQGLEAPDAV----------------KICVDTALfewlawckgglpkwlspaelatfglnidLSYKEKLTPSDLNQKENC
.. | ..|.. |. |.| |.|.||  |. .                .| .||.                             .|. . |    |. . .|
deiyvrssdvdRtlqSAqaflaGlfpplggeivpllrqdlldppfqpipidtvp............................iseddalddtllppdslc

QAYYKRSENFV---REVLK
.|..|  ...    .|||.
paldkllkenlkslsevle

0049226 Phosphoglycerate mutase-like 392-502 6e-10 32.0 In-house 8-103 (342) alignment
Range on Protein: 392-502
Range on HMM: 8-103/342.0
FIIRHGERVDVTFGE-----QWLihcfdqqgkyqrknlnmpkrvpqrpgggqdfkKD---SPITEIGVYQARMTGEALKA---------AGIKISYCYAS
..||||.|  . .|.     .|.                                 .   .. |. |..||.. |..|.             .. | ..|
vliRHGdRtPlakgpldflnewf................................wgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrss

PSLRCSQTAHAVLQGLEAPDAVKICVDT
.. |. |.| |.|.||  |.   |.|..
dvdRtlqSaqaflaGlfppeltpilvpl

0048439 Phosphoglycerate mutase-like 392-496 5.8e-08 25.6 In-house 14-112 (391) alignment
Range on Protein: 392-496
Range on HMM: 14-112/391.0
FIIRHGERV---DVTFGEQWLIHCfdqqgkyqrknlnmpkrvpqrpgggqdF----KKD-SPITEIGVYQARMTGEALKAA-------------GIKISY
 ..|||.|    .... .. |...                           .    . . .. |. |..|.. .|..| .                .. |
vlfRHGaRtPtssypnkldpllnk...........................llpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevy

CYASPSLRCSQTAHAVLQGLEAPDAV
 ..|.. |. |.| |.|.||  |   
vrssdvdRtlqSAqaflaGlfpplgl

subfamily_TFC7_pd Subfamily TFC7 438-590 1.6e-15 48.4 In-house 25-177 (255) alignment
Range on Protein: 438-590
Range on HMM: 25-177/255.0
QDFKKDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGLEAPdavkICVDTALFEWLAWC-KGGLPKWLSPAELATFGLN-IDLSY
.  ..| |..| || ||.  .. ||  ..|    ..||  || .|.... . || |    . ||  . ||.    .  ... .|  .|  |  . |.| |
tgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeeleiP....vyvdrGvgewykpdrrPvilePasnevlskffPsvisldy

KEKLTPSdlNQKENCQAYYKRSE----NFVREVLKECSDDGDILLVGHASTLDSSSRCL
.  ||||  ...|  .  |.| .     |. .| |.  ... ||.| ||.|  .  . |
estltps..ekgeteeelyertkkfwpvfidrvekkfknvetilivthaatkialGmsl

0053607 Phosphoglycerate mutase-like 439-618 1.6e-20 65.9 In-house 22-177 (191) alignment
Range on Protein: 439-618
Range on HMM: 22-177/191.0
DfkkDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVlqgleapdAVKICVDTALFEWLAWCKGGlpkwLSPAELATFGLNIDLSYKEK
    |.|.|| |. ||| ..|.|.. |.|. ..|.|| ||. |||...         ... || .| |. .    |    |. .|||    ..   . . 
g...dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii........glpvevdprlrEidfgdweg....ltleelaekypeelaawlrd

LTPSDLNQKENCQAYYKRSENFVREVLKecsdDGDILLVGHASTLDSSSRCLQGLSARPAMEFSrivqkVPYCGIIMLEE
      .. |. .....| .....|.|.    .|..|.|.|. ..    . | ||.   .. ..     .|..... || 
pldyrppggEsladvaaRvlpaleella....ggnvlvVaHggvirallayllglpleellrln.....lpngsvtvlel

subfamily_TIGAR_pd Subfamily TIGAR 440-507 1.2e-11 36.7 In-house 21-86 (222) alignment
Range on Protein: 440-507
Range on HMM: 21-86/222.0
FKKDSPITEIGVYQARMTGEALKAagIKISYCYASPSLRCSQTAHAVLQGLEAPDAVKICVDTALFEW
.. |.|..| || ||  ... |..   || | ..|. ||  |||...|. |.. .  .. .|  | |.
gqtdtpLsekGveQakrvakrLsn..ekinyifsSdllRAkqTaeiilkalkekkreaverdkrLrEr

0050036 Phosphoglycerate mutase-like 442-600 6.7e-16 50.6 In-house 23-154 (171) alignment
Range on Protein: 442-600
Range on HMM: 23-154/171.0
KDSPITEIGVYQARMTGEALkaagiKISYCYASPSLRCSQTAHAVLqgleapdaVKICVDTALFEWLAWCKGGLPKWLSPAELATfglnidlsYKEKLTP
 |.|.|| |. ||| .||.|     .. ..|.|| ||. |||...|        ... || .| |.      ||..   .|.           .   |  
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil........lpvivdprLrErdfGawegltldeiaakype........wlldlld

SDLNQKENCQAYYKRSENFVREVLkecsddGDILLVGHASTLDSSSRCLQGLSARPAME
  . . |. .....|  ....|.|      |..|.|.|. .. .  . | |||.  ...
lappggEsladvlaRvlpaleell......gnvlvvaHggvirallalllglsleeilr

subfamily_PGAM_pd Subfamily PGAM 442-491 5.9e-08 24.3 In-house 23-72 (248) alignment
Range on Protein: 442-491
Range on HMM: 23-72/248.0
KDSPITEIGVYQARMTGEALKAAGIKISYCYASPSLRCSQTAHAVLQGLE
.|  ..| |. .|. .|.||| |....  .|.|   |. ||....|. |.
vDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeld