Gene PHP in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PHP
Superfamily PHP
Family PHP
Subfamily PHP
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP179_AA protein Get Run
SpurP179_AA_4-119 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PHP 5-119 1.5e-46 147.4 In-house 2-121 (121) alignment 
Range on Protein: 5-119
Range on HMM: 2-121/121.0
ALGRVDDVDIEASGKFKYILIQLS------VGDQTKYIVRGYSHCGYHADIYDEVTPALEKQGINCSCPGGGRIEHDKNAKTILVYGYSMGFGQADHSIA
.| .| ||||.  | |||.||..        ....| .||||... |||||||.|. .|||||... | ||||||||...|.| |||||.|.|.|||...
elakvpdvdidpeGvfkyvlirvtskerkdgaaaskevvrGyaraeyhadiydrvsselekqgldaeclGGGriehdseekkikvyGysvgyGkadhavt

VKILQKKFPDYTsIKSSNEGY
...|..|.|||. |. |.|||
keklktkyPdye.itlsdeGy
0053050 PHP14-like 6-110 1.5e-43 136.6 In-house 2-113 (118) alignment 
Range on Protein: 6-110
Range on HMM: 2-113/118.0
LGRVDDVDIEASGKFKYILIQLSVGDQT-------KYIVRGYSHCGYHADIYDEVTPALEKQGINCSCPGGGRIEHDKNAKTILVYGYSMGFGQADHSIA
| .| .|||. .|.|||.||.. ....|       |.||||.... ||||||.||...|||.|....| ||||||||...|.| |||||.|||.|||.||
lakvpevdideeGvfkYvlikvtlkgltdsggkesklivrglkkaeyHadiyeevskeleklgldleclGGGriehdsekkkikvyGyslgfGkadheia

VKILQKKFPDYT
..||..|.|||.
leilktkypdye
subfamily_PHP_pd Subfamily PHP 8-117 7.3e-49 154.4 In-house 3-114 (114) alignment 
Range on Protein: 8-117
Range on HMM: 3-114/114.0
RVDDVDIEASGKFKYILIQL---SVGDQTKYIVRGYSHCGYHADIYDEVTPALEKQGINCSCPGGGRIEHDKNAKTILVYGYSMGFGQADHSIAVKILQK
.|..|||...|||||.||.|   | |...|.||||||.. ||||||.||...|||.|....| |||||||||..|.| |||||.|||.|||.||..||..
avpevdidskGkfkYvlielttdsegkksktivrgyskaeyhadiyeevkeeleklglkakclGGGriehdkekkkikvyGyskgfGkadheiakeilkt

KFPDYtSIKSSNE
|.||| .|. |||
kypdy.kitisne
Ocnus Janus/Ocnus family (Ocnus) 8-110 5.5e-43 135.1 Pfam-A 3-107 (108) alignment 
Range on Protein: 8-110
Range on HMM: 3-107/108.0
RVDDVDIEASGKFKYILIQLSV--GDQTKYIVRGYSHCGYHADIYDEVTPALEKQGINCSCPGGGRIEHDKNAKTILVYGYSMGFGQADHSIAVKILQKK
.| .|||. .|||||.||.. .  .|..|..|||.... ||||||..|. .|||.|... | ||||||||...|.| |||||.|||.|||.||..||.||
kvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilkkk

FPDYT
..||.
ykdye
Ocnus Janus/Ocnus family (Ocnus) 8-110 5.5e-43 135.1 In-house 3-107 (108) alignment 
Range on Protein: 8-110
Range on HMM: 3-107/108.0
RVDDVDIEASGKFKYILIQLSV--GDQTKYIVRGYSHCGYHADIYDEVTPALEKQGINCSCPGGGRIEHDKNAKTILVYGYSMGFGQADHSIAVKILQKK
.| .|||. .|||||.||.. .  .|..|..|||.... ||||||..|. .|||.|... | ||||||||...|.| |||||.|||.|||.||..||.||
kvpevdideeGkfkYvlikvkikekdeskevvrglkkaeyHadiyekvkkeleklgleteclGGGriehdeekkkikvyGyskgfGkadheiakeilkkk

FPDYT
..||.
ykdye