Gene PDP in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PDPc
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP182_AA protein Get Run
SpurP182_AA_34-433 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PP2Cc_SM00332 35-430 1.9e-67 220.5 In-house 14-274 (274) alignment
Range on Protein: 35-430
Range on HMM: 14-274/274.0
YdSNQLFSNKPGEDRRAIAECMF--TNGVLFGVFDGHGGTACAQAISERLFNYIvAETLPFQTL-Pkalarlqsgemndlvkwhrhpneyklqatadlyk
. |..  ..|..||. ..  ...  ... .|||||||||...|. .|..|.... .|.| ...                                     
k.ssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpeal.keelkkkkdel..................................

eslikyvqanlsvdvldDDDTADVLKTAFDRLDNDFSTEAMRATTEPlgiepvltAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGygaweSIPLTV
                 .||....||.|| ..|... .|. .   |         |  ||.|.||.....|||||||||.||||.|..      ...|.|
.................eddveealkkaflstdeeileeeqskelen........alsGstavvallkkedlyvanvGDSravlcrngk.....avqlsv

DHNVQNLDEVNRIKGGHPshesttVIKNGRLLGELMPLRAFGNIRFKWTAemqrtlmrtfigylppksFHTPPYLITTPEVTHHRLTSNDKFLILASDGL
||.... ||..|||  ..      |...||. | |.  ||||   .|.                     ...||.. .|.|....|||.|.|||||||||
dhkpedederkRikkagg......vvekgrvngglavsrafGdhflkknk..................klkepyitaepdvkvvtltsedeflilaSDGl

WDMLSSDKAVQLVGEHMKSMkasssygvqegaalkdvmkdlkermdilksldtnsaT-----------------Hliryslcgvgndfdlnklaevlslp
||.||....|..| ......                                                      .                         
wdvlsnqevvdivrkllakg....................................ktndpqeaaelldeeairr.........................

daiaRQHRDDMTVTVI
    ....|..|| |.
....ggseDniTvvvv

subfamily_PDP_pd Subfamily PDP 36-434 4.6e-165 542.5 In-house 1-398 (398) alignment
Range on Protein: 36-434
Range on HMM: 1-398/398.0
DSNQLFSNKPGEDRRAIAECMFTNGVLFGVFDGHGGTACAQAISERLFNYIVAETLPFQTLPKALARLQSGE-MNDLVKWHRHPNEYKLQATADLYKESL
||||| ||.| ||||..|... .|||||||||||||.|||.|.|.||..|..|..|. |.| .|...|.||. ...|.|...|..... .....|....|
dsnqLasNePiEDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsel

IKYVQANLSVDVLdddDTADVLKTAFDRLDNDFSTEAMRATTEPLGIEPVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGAWESIPLTVDHN
 ||.|..|...|    .....||.||..||.|.||||.....|   .| .|.|..|.||..|......|.|||.||||||||.... |.||...|. |..
skylqelleaeve...kvkealkkaFlklDkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqt

VQNLDEVNRIKGGHPSHESTTVIKNGRLLGELMPLRAFGNIRFKWTAEMQRTLMRT-FIGYLPPKSFHTPPYLITTPEVTHHRLTSNDKFLILASDGLWD
..| .||.|||  ||..||.|||.||||||||.||||||..|.||..|.|...... ....|.||...|||||...||||.|.|..|||||.||.|||||
adneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkvlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwd

MLSSDKAVQLVGEHMKSMKASSSYGVQE-GAALKDVMKDLKERMDILKSLDTNSATHLIRYSLCGVGNDfDLNKLAEVLSLPDAIARQHRDDMTVTVIYF
.||....|.|||||....|......|.| ...||.|...||||.. ||..|.|.||||||..|.|.... | .|....||.|...||..|||.||||..|
llsneevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkredknaAthLirhalggneag.dkekvsallsiPeelaRmyRDDitvtVvff

DS
.|
ns

0034914 PP2C-like 43-433 2.3e-57 187.1 In-house 32-291 (295) alignment
Range on Protein: 43-433
Range on HMM: 32-291/295.0
NKPGEDRRAIAECM---FTNGVLFGVFDGHGGTACAQAISERLFNYIVaetlpfqtlpkalarlqsgemN-----------Dlvkwhrhpneyklqatad
.|. ||.  .  ..   .....|||||||||| |.|. .||.|.....                     .           .                  
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelll.....................ellekllllltls..................

lykeslikyvqanlsvdvldDDDTADVLKTAFDRLDNDFSTEAMRAtteplgiepVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKgygawESIP
                    ..| ...|..|| ..|... ..|..             |. |..|.||.. .. ||||||||.|||| |..     | ..
....................ledieealrkaflaadeellelallr.........pelagsGtTavvalirgnklyvanvGDSravllrng.....elvq

LTVDHNVQNLDEVNRIKGGHPshesttVIKNGRLLGELMPLRAFGNIRFKWTaemqrtlmrtfigylpPKSFHTPPYLITTPEVTHHRLT-SNDKFLILA
|||||.. | .|. ||.  ..      .. .||..| |.  ||.|  ..|.                 .. ....|... .|.||...|| ..|.||.||
ltvdhkpvnelererilsagg......avshgrvngvlavtRalGdfdlkll................lslllleplvsaePdvtvleltledddfllLa

SDGLWDMLSSDKAVQLVGEHMKSMKAsssygvqegaalkdvmkdlkermdilkslDTNSATHLIRYSLCgvgndfdlnklaevlslpdaiaRQHRDDMTV
||||||.||.. .|..| ..... .                               .. |..|....|                       | .||..||
sDGlwdvlsneeivdivrsllakgld.............................leeaaeeLvdlAla......................rgsrDNiTv

TVIYFD
 |....
vvvrln

0049733 PP2C-like 43-433 6.7e-38 123.4 In-house 15-234 (235) alignment
Range on Protein: 43-433
Range on HMM: 15-234/235.0
NKPGEDRRAIaecmftNGVLFGVFDGHGGTACAQAISERLFNYIVAETLPFQTLPkalarlqsgemndlvkwhrhpneyklqatadlykeslikyvqanl
.| .||. ..      ...||.|.||||| |...  ||.|....... |.. .|                                              
rkvneDavlv......glllfavaDGhgghaagevasellvetllelllelllld.............................................

svdvlddddTADVLKTAFDRLDNDFSTEAMRATteplgiepvLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKgygawESIPLTVDHNVQNLDEVN
         ....|. || .... .  .|..             |. |..|.||.. .. ||||||||.||.| |..     . ..||.||.. | .|. 
.........leealrkaflaaneallelalasp.........elagmgtTavvalldggklyvanvGDsrayllrdg.....klvqltedhspvnelerq

RIKGGHPSHesttvikngRLLGELMPLRAFGNIRFKwtaemqrtlmrtfigylppksfhtppylittPEVTHHRLTSNDkFLILASDGLWDMLSSDKAVQ
||.  ..           | .| |. .||.|.  .|                               |.||...|...| ||.||||||||.||.. .|.
riitaggav.........rvpgrlaltralGdlllk...............................pdvtvlelepgd.flllasDGlwdvlsdeeivd

LVGEhmKSMkasssygvqegaalkdvmkdlkermdilksldT-----------NsathliryslcgvgndfdlnklaevlslpdaiaRQHRDDMTVTVIY
|. .  ...                                            .                                 |  ||..|| |..
llrs..ldl................................eeaaerlvelala.................................rggrDNiTvvvvr

FD
.|
ld

subfamily_PPM1A_pd Subfamily PPM1A 47-433 2.9e-34 111.7 In-house 27-281 (282) alignment
Range on Protein: 47-433
Range on HMM: 27-281/282.0
EDRRAIAECM--FTNGVLFGVFDGHGGTACAQAISERLFNYIVAetlpfqtlpkalarlqsgemndlvkwhrhpneyklqatadlyK----Eslikyvqa
||. ... ..   ... .| |||||.|. .|.  .. | . |.                                           .    |        
EDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..........................................eeelke........

nLSVDVLDDDDTADVLKTAFDRLDNDFSTEAMRATTEpL-GiepvltavtGSCACVAYVNDQDLYVANVGDCRAVLGRSKgygawESIPLTVDHNVQNLD
  . .  ..|.. ..|...| .||.. ...  ...|. .           || | .. |... |..||.||.|||| | .     ... || ||  .. .
.aaleasekdevkealrqgfLaldeairelstdlkta.dks.........GsTavtvlvsekhliianlGDsRavlcrng.....kaaflteDHkpsrpk

EVNRIKGG--HPShesttvikNGRLLGELMPLRAFGNIRFKWTAEMQRTLMrtfigylppksfhtppYLITTPEVTHHRLTSNDKFLILASDGLWDMLSS
| .||.    .          ..|. | |   ||.|   .| . |.. . .                 ... ||||  . ...|.||.||.||.||.||.
EkkRieqAGGsvv........vsRvnGaLAvsRalGDyeykeeeekkaeeq................lvsaepevtsierseeddflvlacDGiwDvlsd

DKAVQLVGEHMKSMKASSSYgvqegaalkdvmkdlkermdilksldtnsathliryslcgvgndfdlnklAEVLsLPDAIARQHRDDMTVTVIYFD
...|.|| ....  .  ..                                                   |. | .  |. .  || ..| |. |.
eevvelvrkrlevadeleev..................................................akal.vdkalekgsrDNlsvlvvlfa

subfamily_PPM1H_pd Subfamily PPM1H 52-233 1e-12 40.5 In-house 54-201 (404) alignment
Range on Protein: 52-233
Range on HMM: 54-201/404.0
IAECMFTNGVLFGVFDGHGGTACAQAISERLfNYIVAETLpfQTLPKALARLQSgemndlvkwH--------RhpneyklqatadlyKESLIKYVQANLS
 .|  . . ..||.||||.|.. | . |. | . .. | |  . . . |.. ..         .        .              |||  .  .    
kseeeklplayfglfDGhaGsgaalvaskll.hkhlkekl..edvlellleksa.........eeeenteess..............kespssvseiyee

VDVLDDDDTADVLKTAFDRLDNDFSTEAMRATTEplgiepvltavTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYgawesIPLTVDH
 ..  ..     | .|| ..|.  . |  . ...            | .|.|| | .. ||||| ||.||.| |..       |||  |.
keiskeeLviGalesaflemDeqiarereayrik...........GGCtalvalvllgklYvanaGDsRailvrkdei.....iplsadf

subfamily_PPM1L_pd Subfamily PPM1L 58-246 2.5e-15 49.5 In-house 33-159 (269) alignment
Range on Protein: 58-246
Range on HMM: 33-159/269.0
TNGVLFGVFDGHGGTACAQAISERLFNYIVAETLPFqtlpkalarlqsgemndlvkwhrhpneyklqatadlykeslikyvqanlsvdvldDDDTADVLK
|.  .|.|||||||   |. . ..| . | .. . .                                                       | |  . . 
tgesffavfdGhGGefaaefakdvlvkaiknkliel.......................................................dadkentep

TAFDRLdndFSTEAMRATTEPLGIEPVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGygawESIPLTVDHNVQNLDEVNRIKG
 .|..|   .  | . . .. |    . . ..|. | .| |...|| |||||| | ||   .|    ..|||. ||  |.. |  ||| 
infskl...ltdeilsvdekllekakraediaGttalialvqesdlivanvGdsrGvlydkrG....kaiplsfdhkpqqvkerkrikk

subfamily_PPM1G2_pd Subfamily PPM1G2 60-352 1.1e-31 102.8 In-house 52-251 (287) alignment
Range on Protein: 60-352
Range on HMM: 52-251/287.0
GVLFGVFDGHGGTACAQAISERLFNYIVAetlpfqtlpkalarlqsgemndlvkwhrhpneyklqatadlykeslikyvqanlsVDVLDDDDTADVLKTA
 .||.|||||||...|.  ...| ..|..                                                        . ....    .|| |
lalfavfDGhGGakvakyagkklikkiak.......................................................kksfkegaleqilkda

FDRLDNDFSTEamratteplgiEPVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGygaweSIPLTVDHNVQNLDEVNRIKgghpshESTTVIKN
| ..|...  .           | .   ..|| | |. .....|||||.|| ||||  .       .  |..||  |. .| .||.      ..  ... 
fletDeellkd...........eklkdesaGstavvvlikeeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkrii......aagGfvel

GRLLGELMPLRAFGNIRFKWTAEmqrtlmrtfigylppksfHTP--PYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMK
.|  |.|   ||.|.  || . .                   .|      ..|.|. ..|...| ||.|| ||.||.|.... |.|| |...| .
nrvngnLalsralgDfefkknvk..................kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsga

PPM_PTC7_SpoIIE 60-351 5.4e-25 81.5 In-house 34-212 (230) alignment
Range on Protein: 60-351
Range on HMM: 34-212/230.0
GVLFGVFDGHGGTAcaqAISERLFNYIVAETLpFQTLPkalarlqsgemndlvkwhrhpneyklqatadlykeslikyvqanlsvdvldddDTADVLKTA
....|..||||| |   |   .|.. ...|   |..|.                                                     . ...|. .
alvvgdvdGhGgra...alamgllrtalrela.fagle.....................................................kpeeilrrl

FDRLDNDFSTEamratteplgiepvlTAVTGSCACVAYVNDQD--LYVANVGDCRAVLGRSKGYgawesipltvdhnvqnldevnrikgghpshES----
...|. |. .|                .. |..|.||... ..  |||||.||....| |..|                               |     
nlalaadlede...............psssgaTavvalidpstgklyvanaGdsppllvrddgg..............................ereriv

-----------TtvikngrllgelmplrafgniRFKWTAEMQRTLMRTFIGYlppksfhTPPYLITTPEvTHHRLT-SNDKFLILASDGLWDMLSSDKAV
           .                     |  .......    ... |       |  .    |. | . .. ..|.|||||||||||.||.. .|
agglpslGilpg.....................rvfgvlavslapGdlllly.......tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelv

QLVGEHMKSM
.|| ..... 
dlvrdelekp

PP2C_SIG_SM00331 61-430 2.1e-08 27.0 In-house 31-215 (217) alignment
Range on Protein: 61-430
Range on HMM: 31-215/217.0
VLFGVFDGHGGTACAQAISERLFNYIVAETLPFQTLPKALARLQSgEMNDLvkwhrhpneyklqatadlykeslikyvqanlsvdvlddddtadvlktaf
.|. |.||.|. ..|.|.|..| . .  .    ..|..|| || .  ....                                                 
lllvvaDgmGkGlaAaaassqlrtalrellsegeelsqalkrlnr.aiyee.................................................

drldndfsteamratteplgiepV--LTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGAWESIpltvdhnvqnldevnrikgghpshesttvik
                              .  ....   ... |..||.||.| .| |....  . .                                
.......................keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd...............................

ngrllgelmplrafgnirfkwtaemqrtlmrtfigylppK-----------SfhtppylittPEVTHHRLTSnDKFLILASDGLWDMLSSDKavqL----
                                       .           |          ....   |   . .|.|..|||... |...   .    
.......................................vegaplGlepevs..........vdirelelek.gdllllytDGltearsekg...faeer

----VGEHMksmkassSYGVQEG--AALKDVMKDLKERMDilksldtnsathliryslcgvgndfdlnklaevlslpdaiarqhRDDMTVTVI
    . ...       .  .||   . .....  .|..                                              .||.|| |.
leeiledlv.......dseaqelaqkiveellelakgsng............................................eDdiTvvvv

subfamily_KAPP-like_pd Subfamily KAPP-like 125-257 9e-07 21.2 In-house 51-168 (266) alignment
Range on Protein: 125-257
Range on HMM: 51-168/266.0
ATADLYKESLIKYVQANLSVDVLD-DDDTADVLKTAFDRLDNDFSTEAMRATTEPLGIepVLTAVtgscacvayvNDQDLYVANVGDCRAVLGRSKgyga
|. .|... | |...     |  |   |  ..|. ||. .|. ..      .|  | .  | ..           . . | ||||||  | | |      
aakklfpkelekllkstkqddGGdniydqskllenafkevdaklkdfeyeGatatlal..vwsdG..........qqrylqvanvGdssaflsrGn....

wESIPLTVDHNVQNLDEVNRIKG-GHPSHESTTVI
 ||. |. ||. .. .|  |||  | .  .. | |
.eslelskdhkakdpeekqrikddGitlsdnqtri

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 125-257 9.1e-07 21.0 In-house 50-178 (276) alignment
Range on Protein: 125-257
Range on HMM: 50-178/276.0
ATADLYKESLIKYVQA-NLSVDVLDD-----DDTADVLKTAFDRLDNDFSTEAMRATTEplgiepVLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRS
|. .|. . | |.... | |.   ||      |  ..|. .|. .|. ..      .|        |. |  .       ... | ||||||  | | | 
aakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdfeyeGata......tlalvwsdGeeqqqqqqrylqvanvGdssaflsrG

KgygawESIPLTVDHNVQNLDEVNRIKG-GHPSHESTTVI
      ||. |. ||. .. .|..|||  | .  .. | |
n.....eslelskdhkatdpeekqrikddGitlsdnqtri

subfamily_PPM1D_pd Subfamily PPM1D 127-246 2.4e-11 36.3 In-house 50-166 (309) alignment
Range on Protein: 127-246
Range on HMM: 50-166/309.0
ADLYKESLIKYVQANLSVDVLDDDDTADVLKTAFDRLDNDFSTEAMRATTEPLGiepvLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKG-YGAWE
|   .| |..... .  .   ...|  . .. ||  . .    .    . .  |    | . .|. | |  . ...||||.||| ..||| ..     ..
akfarehlwsvikkqkkflssepedvleAireaflatheamkkkleeWpktksg....llstaGttasvviirreklyvahvGDsaivlgvkepkekklr

SIPLTVDHNVQNLDEVNRIKG
. .||.||  ....|..||. 
akeltkdHkPespeekeriee

PPM_PTC7 148-354 1.4e-41 135.7 In-house 68-243 (259) alignment
Range on Protein: 148-354
Range on HMM: 68-243/259.0
DDDDTADVLKTAFDR--LDNDFST-EAMratteplgiePvLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGawesIPLTVDHNVQNLDEVNRI
..... ..|...| .  .|. . . ||.            .    ||.| ||......||||||||.||||.||..       .||.||...| ||..||
eleklekalrksflaldtdeelkssean..........t.epstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRi

KGGHPSHESTtviKNGRLLGELMPLRAFGNIRFKWTAEmqrtlmrtfigylppksfhTPPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLV
.| . |...    .|||. | |   ||||  ..|                       ...... .|..... ....|.|||||||||||..|...||.||
egaggsvsnv...gngrvngvlavsRafGdfelkpket...................eeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlv

GEHMKS---MKAS
 .....   |.|.
rselskkdpmeaa

PP2C Protein phosphatase 2C 148-352 1.9e-41 135.4 Pfam-A 68-233 (255) alignment
Range on Protein: 148-352
Range on HMM: 68-233/255.0
DDDDTADVLKTAFDR-LDNDFSTeaM--RatteplgiePvLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGawesIPLTVDHNVQNLDEVNRI
....  ..|. .| . .|. . .  .  .           .    ||.| ||......||||||||.||||.|...        ||.|| ... ||..||
elekvekalrksfladtdeelks..skan.........t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRI

KGGHPSHESttvikNGRLLGELMPLRAFGNIRFKWTAemqrtlmrtfigylppksfhtPPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLV
.. . |..      |||. | |   ||.|  ..|                        ... .  |.||...||..|.|||||||||||.||...||.||
eeaggsvsn.....ngrvngsLavsRalGdfelkpke.....................eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlv

GEHMKSMK
 ......|
rselskkk

PP2C Protein phosphatase 2C 148-352 1.9e-41 135.4 In-house 68-233 (255) alignment
Range on Protein: 148-352
Range on HMM: 68-233/255.0
DDDDTADVLKTAFDR-LDNDFSTeaM--RatteplgiePvLTAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGawesIPLTVDHNVQNLDEVNRI
....  ..|. .| . .|. . .  .  .           .    ||.| ||......||||||||.||||.|...        ||.|| ... ||..||
elekvekalrksfladtdeelks..skan.........t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRI

KGGHPSHESttvikNGRLLGELMPLRAFGNIRFKWTAemqrtlmrtfigylppksfhtPPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLV
.. . |..      |||. | |   ||.|  ..|                        ... .  |.||...||..|.|||||||||||.||...||.||
eeaggsvsn.....ngrvngsLavsRalGdfelkpke.....................eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlv

GEHMKSMK
 ......|
rselskkk

subfamily_PPM1K_pd Subfamily PPM1K 148-278 4e-12 38.8 In-house 63-182 (263) alignment
Range on Protein: 148-278
Range on HMM: 63-182/263.0
DDDDTADVLKTAFDRLDNDFSTEAMRATTEPlgiepvLTAVTGSCACVAYVND-QDLYVANVGDCRAVLGRSkGygawESIPLTVDHNVQNLDEVNRIKG
 ..|   ||| ||. ||....  .    .|        .  .|. | |. . | ..| .|..|| ||.| |  |    ..  || ||. .  .| .||| 
kekdleivlknafeeldkklkrylefsvaea......ellssGttatvsllrdGtelvlaslGdsrailcrn.G....kakkltrdhdPeleeekerika

GHPSHESTTViKNGRLLGELMPLRAFGNIRFK
   | |....  . .. | |   |..|.. .|
agGsvewnsl.gkplvngrlamtrslGdldlk

subfamily_PPM1E_pd Subfamily PPM1E 148-246 9.3e-07 21.3 In-house 72-154 (265) alignment
Range on Protein: 148-246
Range on HMM: 72-154/265.0
DDDDTADVLKTAFDRLDNDFSTEAMRATTEplgiepvltavTGSCACVAYVNDQDLYVANVGDCRAVLGRSKgygawESIPLTVDHNVQNLDEVNRIKG
. .|.|. || || ..|. | . |.| . .           .|| | |. .. . |||| .|| .|.| |       | . |.  |. .. || .||. 
lkedpaealkeafkltDerflqkaereklk...........sGstavvvliekdqlyvaWlGDsqallvrkg.....eavqlmkpHkPeredEkkRiee

subfamily_ILKAP_pd Subfamily ILKAP 149-279 3.2e-15 49.0 In-house 82-198 (293) alignment
Range on Protein: 149-279
Range on HMM: 82-198/293.0
DDDTADVLKTAFDRLDNDFSTEAMRATteplgiePVLTavTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGA-WESIPLTVDHNVQNLDEVNRIKgg
. .    |  .| . |..| ..| .|.       ||     || | |  | |. |||||.|| .||| | |  |    |..||.||.  ...| .||.  
ekeikkclvdsfkktdeefLklaskak.......PvWk..dGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriq..

hpshESTTVIKNGRLLGELMPLRAFGNIRFKW
     . .|...||.|| |   |. |. ||| 
....kaGgvvrdgrvlGvlevsrsiGdgrfkr

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 183-275 3e-09 29.5 In-house 92-175 (255) alignment
Range on Protein: 183-275
Range on HMM: 92-175/255.0
PvltAVTGSCACVAYVNDQDLYVANVGDCRAVLGRSKGYGAwesiPLTVDHNVQNLDEVNRIKG--GHPSHEsttvIKNGRLLGELMPLRAFGNI
|      |. | .... ..  |.||||| |.||.. .|        |..||. .. .| .||.   |    .     .  |. | |   ||.|..
p...kfiGttaasvliiedkvyianvGdsrvvlcqkdgtak....rlsldhkPseeseekriselGGtvvst....vvtsrvnGtlavsralGds

subfamily_PPM1G_pd Subfamily PPM1G 189-354 9.4e-24 77.2 In-house 296-435 (473) alignment
Range on Protein: 189-354
Range on HMM: 296-435/473.0
TGSCACVAYVNDQDLYVANVGDCRAVLGRSkgygaWESIPLTVDHNVQNLDEVNRIKgghpsHESTTVIKNGRLLGELMPLRAFGNIRFKWTAEMQRTLM
 |. |.|| .....|.|||.||.|.|| |.      . . | .||  ..  | .||.     .   .| ..||. | |   ||.|.  .| ..|..    
sGttAvvaLlkekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRie.....kAGGkvdedgRvnGGLnlsRAlGDhaYkkneeLplkeq

RtfigylppksfhtppyLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKAS
                 .   |..  . ||..|.||.||.||.|....|.. |. | ...|  . |
m................isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvraklkkgees

subfamily_TAB1_pd Subfamily TAB1 189-432 3.8e-18 58.4 In-house 129-331 (333) alignment
Range on Protein: 189-432
Range on HMM: 129-331/333.0
TGSCACVAYVNDQDLYVANVGDCRAVLGRSKGygAWESIPLTVDHNVQNLDEVNRIKGGHpsHESTTvIKNGRLLGELMPLRAFGNIRFKWTAEMQRTLm
 |. | || .  ..|||||||| ||.| ..|     .   | |||...| ||. |.|.     .  . ||. ..||. .. |. |. . |   .    | 
gGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLG..ldieq.ikrnkrlgskentRsiGdykvkkgykdvdil.

rtfigylppKSFHTPPyLITTPEVTHH-RLTSNDKFLILASDGLWDMLSSDKAVQlvGEHMKSMKASSSYGVQEGAALKDVMKDLKERMDILKSLDTNSA
         .| . .|  |..|...    ..   .||.| |||.   |   .  .     .... .  .  ... | |.|| ... ... .  .    | 
.........ssakgeP.viaePdiqgaypiddityflvlmSdGvyktLeevtgpe..tsnvenillevitelekqatlqdvAqavvdkvkrkHkdaylss

ThliryslcgvgndfdlnklaevlsLPDAIARQHRDDMTVTVIYF
                            |   ..|||||. |. |
a........................seravicrkrddmtllvlkf

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 190-246 4e-12 39.3 In-house 86-143 (292) alignment
Range on Protein: 190-246
Range on HMM: 86-143/292.0
GSCACVAYVNDQ-DLYVANVGDCRAVLGRSKGYGAWESIPLTVDHNVQNLDEVNRIKG
....  | |.|.  |..||||| ||.|||  |    | |||. ||  .. || .||. 
ttavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilr

subfamily_PP2D1_pd Subfamily PP2D1 201-275 2.5e-06 19.5 In-house 188-255 (492) alignment
Range on Protein: 201-275
Range on HMM: 188-255/492.0
QDLYVANVGDCRAVLGRSkGygawESIPLTVDHNVQNLDEVNRIKGGHPSHESTTviKNGRLLGELMPLRAFGNI
  ||.||.|. .||| |  |    ..| || .|. .|  | .|..    .  ..   |||.  | |   |  ||.
gvlyianaGnvqAvLcre.G....kaiiLtreHtprnkkERtRvekagsvvvkse..knglvnGildttRGLGny

subfamily_PHLPP_pd Subfamily PHLPP 300-353 1.2e-07 23.9 In-house 168-221 (246) alignment
Range on Protein: 300-353
Range on HMM: 168-221/246.0
FHTPPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKA
... |... .|.| .  ||..| .||. .. ||..|| |.||. | .. ... |
tflfPvvlPkphvrevlLteqdellivGnkalWevlsideaveavrkeedplva

subfamily_PPM1E_pd Subfamily PPM1E 303-354 1.7e-10 33.5 In-house 183-234 (265) alignment
Range on Protein: 303-354
Range on HMM: 183-234/265.0
PPYLITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKAS
 ||... ..|.. .|......||||.|||||..  ...|.|| |.... . .
kpyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladgaed

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 303-354 4e-10 32.4 In-house 178-230 (255) alignment
Range on Protein: 303-354
Range on HMM: 178-230/255.0
PPYLITTPEVT-HHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKAS
 |.... |...   . . .||||||| ||.||..| ..||..| .  .. ||.
ePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagisdpekaa

subfamily_PPM1H_pd Subfamily PPM1H 303-353 6.8e-09 27.9 In-house 302-356 (404) alignment
Range on Protein: 303-353
Range on HMM: 302-356/404.0
PPYLITTPEVTHHRLT----SNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKA
 |.| ..|||.   ||    ..|. ||||.|||||.|| ... ..| | ..... 
kPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvep

subfamily_PPM1L_pd Subfamily PPM1L 305-350 7e-09 28.3 In-house 192-238 (269) alignment
Range on Protein: 305-350
Range on HMM: 192-238/269.0
YLITTPEVTHHRLT-SNDKFLILASDGLWDMLSSDKAVQLVGEHMKS
 .|..|..    |   . .||||||||||| .| ..||. . |..| 
lviadpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlke

subfamily_ILKAP_pd Subfamily ILKAP 306-356 1.8e-10 33.4 In-house 201-251 (293) alignment
Range on Protein: 306-356
Range on HMM: 201-251/293.0
LITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKASSS
.|.||.|.. .|| ||.|..|| ||||. .| |..|. . . ... . ...
vistPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddrk

subfamily_PP2D1_pd Subfamily PP2D1 306-359 6.4e-09 28.0 In-house 264-317 (492) alignment
Range on Protein: 306-359
Range on HMM: 264-317/492.0
LITTPEVTHHRLTSNDKFLILASDGLWDMLSSDKAVQLVGEHMKSMKASSSYGV
.|. |..|   |. ...||.||| |||..|| .  ..|| . .. .| .   ..
vipePkttsvkldeaaqflvlAsnGlWevlseeevlsLvkqtlaiyksrvraen

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 306-346 4.4e-08 25.3 In-house 199-240 (276) alignment
Range on Protein: 306-346
Range on HMM: 199-240/276.0
LITTPEVTH-HRLTSNDKFLILASDGLWDMLSSDKAVQLVGE
||..| |.    ||  |||||.|||||||..| ..|.. |  
lisepyvsnrilltpfdkflivasdGlwdvisGkdaiekvks

subfamily_KAPP-like_pd Subfamily KAPP-like 306-346 4.4e-08 25.5 In-house 189-230 (266) alignment
Range on Protein: 306-346
Range on HMM: 189-230/266.0
LITTPEVTH-HRLTSNDKFLILASDGLWDMLSSDKAVQLVGE
||..| |.    ||  |||||.|||||||..| ..|.. |  
lisepyvsnrilltpfdkflivasdGlwdvisGkdaiekvks

subfamily_PPM1D_pd Subfamily PPM1D 309-356 2.3e-10 33.0 In-house 225-273 (309) alignment
Range on Protein: 309-356
Range on HMM: 225-273/309.0
TPEVTHHRLTSNDK-FLILASDGLWDMLSSDKAVQLVGEHMKSMKASSS
 |.|....|. |.. |.||||||||..|....||..| .. .  .  ..
ePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkee

PPM_PTC7_motif 325-352 1.2e-09 31.5 In-house 1-33 (51) alignment
Range on Protein: 325-352
Range on HMM: 1-33/51.0
ILASDGLWDMLSSDKAVQLVGEHMKS-----MK
|||||||||.||...||.|| .....     ..
iLAsDGLWDvlsdqeavdlvrdqlskkglspqe