Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0034914 | PP2C-like | 95-289 | 4.3e-44 | 143.6 | In-house | 20-224 (295) | alignment | ||
Range on Protein: 95-289
Range on HMM: 20-224/295.0
VGRIGKDSLIGRRAENEDRICIKE----LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER--------EHDLQIVLKNAFEDLNNKLTRYLYFhy
. |.| | .||| .|||.... |...||..|.|||| |. | ......| .|. .||. ..|.. .|..|| ....| ....
llrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelall..
pETEYENSGSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWnslgkPLVNSVLTMTRSFGDVTLK-------
. |. .||.||.| |. || |..||.|||||.|.|||....||.||.| | .|.|||..||| .. . || || .||..||. ||
.rpelagsGtTavvali.rgnklyvanvGDSravllrngelvqltvdhkpv.nelererilsaggavsh.....grvngvlavtRalGdfdlklllslll
-RYGVIATPETRSLE
...|.|.|....||
leplvsaePdvtvle
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 97-290 | 1.1e-112 | 368.5 | In-house | 5-197 (263) | alignment | ||
Range on Protein: 97-290
Range on HMM: 5-197/263.0
RIGKDSLIGRRAENEDRICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYLYFHYPETEYENSGSTATV
.|||||||.||||||||..|||.|.||||..|||||||.|.|.||..||..||..||.|.||.||||||||.|..||.|||.|...|.|...||.||||
svGkdsliGkraenedriklkeldpellyvavfdGhaGsaaadfvhdklekilkrllekekdleivlknafeeldkklkrylefsvaeaellssGttatv
SLLRNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEYNTtEKERIKAAGGSFTWNSLGKPLVNSVLTMTRSFGDVTLKRYGVIATPETRSLEV
||||.|.|||||.|||||||||||||||.||.|||||... |||||||||||..||||||||||..|.||||.||..||||||||||||.||.|
sllrdGtelvlaslGdsrailcrnGkakkltrdhdPelee.ekerikaagGsvewnslgkplvngrlamtrslGdldlkryGviatPetkslkv
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 97-277 | 1.2e-33 | 109.7 | In-house | 13-195 (282) | alignment | ||
Range on Protein: 97-277
Range on HMM: 13-195/282.0
RIGKDSLIGRRAENEDRICIKELHPNL---LYVGIFDGHAGSMAVDYVHHNLEFHLKF---------WLEREHDLQIVLKNAFEDLNNKLTRYlyFHYPE
|.| .| |.|.|.||. .. ..| . .||||||| ...||...| .. . ..... .|...| .|.... . .. .
rygvssmqgwrvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairel..stdlk
TEyENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTwnslgKPLVNSVLTMTRSFGDVTLKRY
|. ..|||||.. |.. ..|..||||||||.|||||||..||.|| |. ...||.||..|||| . . || | ..|..|| ..|.
ta.dksGsTavtvlvs.ekhliianlGDsRavlcrngkaaflteDHkps.rpkEkkRieqAGGsvv.....vsRvnGaLAvsRalGDyeykee
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 97-284 | 1.9e-28 | 92.4 | In-house | 7-186 (255) | alignment | ||
Range on Protein: 97-284
Range on HMM: 7-186/255.0
RIGKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLtrylyfhypeTEY-ENSG
..|. .||||. ||.. | ... |. .||||.|. | .. ..|. |. |. .. . .||.|..... .. .|. |
kvgfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPvkslkkaykeistqi..........serpkfiG
STATvSLLRNGNELVLANLGDSRAILC-RNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNsLGKPLVNSVLTMTRSFGDVTLKRYgVIATPE
.||. |.| .. ..||.||||..|| ..| ||||. || | . |..||...|| . || |...|..||. |. . |.. |.
ttaa.svliiedkvyianvGdsrvvlcqkdgtakrlsldhkPs.eeseekriselGGtvvst.vvtsrvnGtlavsralGdsflePf.vvpdPd
|
|||||||||
PP2Cc_SM00332 | 99-287 | 6.4e-40 | 130.2 | In-house | 13-206 (274) | alignment | |||
Range on Protein: 99-287
Range on HMM: 13-206/274.0
GKDSLIGRRAENEDRICIKEL---HPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD-----LQIVLKNAFEDLNNKLTRYLYFHYPETeyENS
||.| |.| ..||..... . . |..|.||||.|| ....| .| .|| |. . | . .||.||........ . .| ..|
gkssmqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..als
GSTATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslgkpLVNSVLTMTRSFGDVTLKR------YGVIATPE
||||.|.||.... |..||.|||||.|||||||..|..|| | . .|..|||.|||. .. || .| ..|.|||. ||. ...|.|.
Gstavvallkked.lyvanvGDSravlcrngkavqlsvdhkp.edederkRikkaggvvekg.....rvngglavsrafGdhflkknkklkepyitaepd
TRS
.
vkv
|
|||||||||
0049733 | PP2C-like | 99-285 | 2.6e-31 | 101.9 | In-house | 6-170 (235) | alignment | ||
Range on Protein: 99-285
Range on HMM: 6-170/235.0
GKDSLIGR-RAENEDRICIkelhpNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLERE--HDLQIVLKNAFEDLNNKLTRYLYFHYpetEYENSGSTAT
| | ||| | .|||.... .||.....||| |. | ... ..| .|. .|.. .||. .|..||. .|. | .. . .. |. .|.||.
gaasdigrvrkvneDavlv.....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallelalasp...elagmgtTav
VSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFtwnslgkpLVNSVLTMTRSFGDVTLKrygviatPET
| ||. |. |..||.|||||.|.|.||. .|| || | | .|..||..||| . |. .| .||..|| .|| |..
valld.ggklyvanvGDsrayllrdgklvqltedhspv.nelerqriitaggav........rvpgrlaltralGdlllk.......pdv
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 99-278 | 3.8e-29 | 94.5 | In-house | 22-196 (287) | alignment | ||
Range on Protein: 99-278
Range on HMM: 22-196/287.0
GKDSLIGRRAENEDRICI------KELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLE-REHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSG
| .. | | . || . |. ...| ....|||| |. . |. ..| .. . .| |. .||.|| .....|.. ... |..|
gssamqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkd.....eklkdesaG
STATVSLLRNGNeLVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYG
|||.| |... . |. || |||||.|. .|..| |. || |. ...||.||.|||| | || .| . |..|| . |.
stavvvlikeek.lyvanaGDsravlsskgnvkalsfDhkPq.eesekkriiaagGfvelnr.....vngnLalsralgDfefkknv
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 101-175 | 4.2e-06 | 19.0 | In-house | 24-100 (473) | alignment | ||
Range on Protein: 101-175
Range on HMM: 24-100/473.0
DSLIGRRAENEDR-ICIKELHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-EREHDLQIVLKNAFEDLNNKLT
. | |...|| || .|. . ...||| |. || ..| || .| |.. |..|| .|..||.
samqGwrvsqEDahncitdldedtslfavyDGHGGkevakyvakklpdllkaqkgykegdvekaleeaflalDeklk
|
|||||||||
PP2C | Protein phosphatase 2C | 102-288 | 3.9e-38 | 124.5 | Pfam-A | 7-196 (255) | alignment | ||
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... . . ....||||.|..| .| . .|| .|| . . . .. .|...|. ....|.. . || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs
TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. . . || .| ..|..||. ||. . |.| |...|
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv
|
|||||||||
PP2C | Protein phosphatase 2C | 102-288 | 3.9e-38 | 124.5 | In-house | 7-196 (255) | alignment | ||
Range on Protein: 102-288
Range on HMM: 7-196/255.0
SLIGRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED-LNNKLTRylyfHYPETEYENSGS
.| |.| ..||.... . . ....||||.|..| .| . .|| .|| . . . .. .|...|. ....|.. . || ..|||
elqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflelekvekalrksfladtdeelks....skantepsksGs
TATVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWnslgKPLVNSVLTMTRSFGDVTLKR---YGVIATPETRSL
||.|.|.|. . | .||.|||||.|||...|| .||.||.|. .. |.|||..||||. . . || .| ..|..||. ||. . |.| |...|
tavvalirgkk.lyvAnvGDSravLcrkdnakkeltedHkps.dedEreRIeeaggsvsn....ngrvngsLavsRalGdfelkpkeeqlvsaePdvtsv
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 102-288 | 3.9e-25 | 81.6 | In-house | 11-202 (269) | alignment | ||
Range on Protein: 102-288
Range on HMM: 11-202/269.0
SLIGRRAENEDRICIKELHPN---LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWL-----EREHDLQIVLKNAFEDLNNKLTrYLYFHYPETEYENSGST
|. ||| . |||. |.| | ....|||| | .| ..... | .| | ..|. . | .. ..| . . . ..... .|.|
svlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentepinfsklltdeilsvd.ekllekakraediaGtt
ATVSLLRnGNELVLANLGDSRAILC-RNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYG-VIATPETRSL
| ..|.. ...|..||.|||| .|. ..||| |. || | .. |. ||| ||| ... | |. ||...|..|| || |||.|. ..
alialvq.esdlivanvGdsrGvlydkrGkaiplsfdhkp.qqvkerkrikkaGGfiafr..GvwrvaGvlatsralGdyplkdknlviadpdiltf
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 104-266 | 9.5e-07 | 21.3 | Pfam-A | 6-174 (212) | alignment | ||
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| . | . . ||. . .. ... .|. .||.| . . ......|.. . . . . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll
VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... . |.|....|. .. || |.| . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 104-266 | 9.5e-07 | 21.3 | In-house | 6-174 (212) | alignment | ||
Range on Protein: 104-266
Range on HMM: 6-174/212.0
IGRRAENEDRICIKELHPNLLYVgIFDGHAGS----MAVDYVHHNLEFHLKFWLEREHDLQivLKNAFEDLNNKLTRYL----YFHYPETEYENSGSTAT
. ... ..|.. |.| . | . . ||. . .. ... .|. .||.| . . ......|.. . . . . | .. ..| .
rrkgkpcqDalaireasdgwlla.VADGaGsakrSdkGarlaveaagealeklleeeseqe..eeallrqieneilasvklkqeaeaqqeelkdyatTll
VSLlRNGNELVLANLGDSRA-ILCRNGKAKRLTNDHDPEY-NTTEKERIKAAGGSFTWNSLGKPLVNSVLTMT
. . ....|.|....||... . |.|....|. .. || |.| . ..|.... ...| .. .. .| ||
lav.itpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeelrirrlklepgdalllmT
|
|||||||||
PPM_PTC7 | 105-287 | 9.2e-38 | 123.1 | In-house | 10-200 (259) | alignment | |||
Range on Protein: 105-287
Range on HMM: 10-200/259.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHD--LQIVLKNAFED--LNNKLTRylyfHYPETEYENSGSTA
|.| ..||. ... . ....||||.|..| .|.. .|| .|| . | . |. .|...|. ....|.. . || ..|||||
gfrksmedahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeeleklekalrksflaldtdeelks....seantepstsGstA
TVSLLRNGNeLVLANLGDSRAILCRNGKAK-RLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKR-----YGVIATPETRS
.| |... . | ||.|||||.|||.|.|. .||.||.|. |. |.|||..||||. . |. || || ..|.|||. ||. |.|.|.. |
vvalitgsk.lyvAnvGDSravLcrsgnavkqltedHkps.nedEreRiegaggsvsnv..gngrvngvlavsRafGdfelkpketeeqlvsaePdiss
|
|||||||||
PPM_PTC7_SpoIIE | 105-276 | 5.3e-20 | 65.2 | In-house | 10-162 (230) | alignment | |||
Range on Protein: 105-276
Range on HMM: 10-162/230.0
GRRAENEDRICIKE------LHPNLLYVGIFDGHAGSMavDYVHHNLEFHLKFWLEREHD-LQIVLKNAFEDLNNKLTRYlyfhypeteYENSGSTATVS
|.| ..||. ... . |.||..||| |.. ... | |. .... . .|..... |. .|. . ..||.||.|
garksmedahispansekssggrlalvvgdvdGhGgra..alamgllrtalrelafaglekpeeilrrlnlalaadlede.........psssgaTavva
LLRNGN-ELVLANLGDSRAILCRN-GKakrltndhdpeynttEKERIkAAGGSFTwNSLGKPLVNSVLTMTRSFGDVTLKR
|... . .| .||.|||...|.|. |. |.||| .||| ... |. ||......||. |.
lidpstgklyvanaGdsppllvrddgg...............ereri.vagglps.lGilpgrvfgvlavslapGdlllly
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 105-250 | 1.9e-19 | 62.9 | In-house | 11-172 (309) | alignment | ||
Range on Protein: 105-250
Range on HMM: 11-172/309.0
GRRAENEDRICIKELH------PNLLYVGIFDGHAGSMAVDYVHHNLEFHL----KFWLEREHDLQIVLKNAFEDLNNKLTRYlYFHYPETE---YENSG
| | ||...|. . . .|..|||| | | .....| . ||. . ..|.. ...|| ...... . . ..|.|. . .|
GgrkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkk.leeWpktksgllstaG
STATVSLLRNgNELVLANLGDSRAILCRNGK------AKRLTNDHDPEYnTTEKERIKAAGGSFT
.||.| ..|. ..| .|. |||...| . . || ||.|| || .|||||. .||. .
ttasvviirr.eklyvahvGDsaivlgvkepkekklrakeltkdHkPes.peekerieelGGeva
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 106-285 | 1.3e-22 | 73.7 | In-house | 3-196 (292) | alignment | ||
Range on Protein: 106-285
Range on HMM: 3-196/292.0
RRAENEDRICIKELHPNLLY-VGIFDGHA--GSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlYFhypeTEYENSGSTATVSLLRNG
. ||.|| .. | | . ..||| | .. .|| .| . .| | . |. || . . . |....... . |..
nkkenqdrfllvegsealtflaavldGhGvnGdkvaqlaedtlevelleltrqlqelsealllrildiaakldkl.ti....daresattavvcarvrdd
NELVLANLGDSRAILCR-----NGKAKRLTNDHDPEyNTTEKERIKAAGGSFT------WNSLGKPLV------NSVLTMTRSFGDVTLKRYGVIATPET
.|.|||.|||||.| | . . . |..|| || . |..||..||| . | | . | . |...|. ||. |. ||.| ||
ralilanvGdsrallgrclggsdyeliPlsrdhkPe.dPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdfhlfeaGvvaePel
|
|||||||||
PP2C_SIG_SM00331 | 111-229 | 1e-07 | 24.8 | In-house | 18-126 (217) | alignment | |||
Range on Protein: 111-229
Range on HMM: 18-126/217.0
EDRICIKELHPNLLYVGIFDGHA-GSMAVDYVHHNLEFHLKFWLERehdlqivlkNAFEDLNNKLTR----YlyfhypeTEYENSGSTATVSLL-RNGNE
.| .. .|. | . ..||. | | . .. ... |. ...... ..| | .| .... |... |. ....
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg.........eelsqalkrlnraiyee.......keekgmfaTlllalydfssgk
LVLANLGDSRAILCRNGKAKRLTND
| .||.|||| .| |.|| . . |
lsyanaGdsrpyllrdgklveilkd
|
|||||||||
subfamily_PHLPP_pd | Subfamily PHLPP | 112-286 | 1.4e-06 | 20.4 | In-house | 17-181 (246) | alignment | ||
Range on Protein: 112-286
Range on HMM: 17-181/246.0
DRICIKELHPNLLYvGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTrylyfhypeTEYENSGSTATVSLLRNGN-------E
.. |...|. . || |.|||.. . . . .. || ...... . .|| . ..|| .. | ||.| . |.|. .
nklcvaalsvealy.GlfdGdrneelssllqrlmkdvlkeevqkdkneeeymkntllvaqrklG.........eaGeklgsaallilirhdkvdPaksfs
LVLANLGDSRAILCRNGKAKRLTNDHDPEYNttEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKRYgVIATPETR
| .|. | |.|.|||| ||.. . | . | .||| | . | .. | .|.|.. || .| . | . |. .|. |
LevAsvGtlqavliRngkklrlsksyviekd..elkrikeakaiitedn..k..ingviestrllGytflfPv.vlPkphvr
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 121-288 | 4.1e-29 | 94.6 | In-house | 38-195 (265) | alignment | ||
Range on Protein: 121-288
Range on HMM: 38-195/265.0
PNLLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEREHDLQIVLKNAFEDLNNKLTRYlyfhyPETEYENSGSTATVSLLRNgNELVLANLGDSRAILCRN
.. . ..||||.|. | .| ..| .| . ..| . ||.||. ....... | | .||||| | |... ..| .| ||||.|.|.|.
keraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflqk.....aereklksGstavvvliek.dqlyvaWlGDsqallvrk
GKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslGKPLVNSVLTMTRSFGDVTLKRYgVIATPETRSL
|.| .|.. | || . ||.||..||| . |. || ||...|. |||.||.| |.. ... ..
geavqlmkpHkPe.redEkkRieeagGlvvvi..gawRvnGvLsvsRaiGDvklkpy.vsgeadvaev
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 123-288 | 1.1e-23 | 76.8 | In-house | 43-210 (293) | alignment | ||
Range on Protein: 123-288
Range on HMM: 43-210/293.0
LLYVGIFDGHAGSMAVDYVHHNLEFHLKFWLEReHDLQI---VLKNAFED-LNNKLTRYLYFHYPETEYENSGSTATVSLLRNgNELVLANLGDSRAILC
. | ..||||||| | ... ..|. ... | . .|.. .|... | ... .| .. |||||| | . | | ||||||.|.|.
vsyyavfdGhaGsrasefaaeklhkkileklpk.sdvsakekeikkclvdsfkktdeefLklaskakPvWkdGstatvvlvld.nvlyvanlGdskavlv
RNGKAKR------LTNDHDPEyNTTEKERIKAAGGSFTWNSlgkplVNSVLTMTRSFGDVTLKRYGVIATPETRSL
|. .. . || ||.| . |..||. |||. . . |. || ..|| || || |||.||... .
rkkeegdkiasvvLtkdhtpv.kyeerkriqkaGgvvrdgr.....vlGvlevsrsiGdgrfkrlGvistPdvkkc
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 124-283 | 3.5e-15 | 48.7 | In-house | 35-193 (266) | alignment | ||
Range on Protein: 124-283
Range on HMM: 35-193/266.0
LYVGIFDGHAGSMAVDYVHHNLEFHLKFWLER---------EHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGNELVL--ANLG
..|||||| | | .. .. |. |.. .| . .|.|||.....|| . ||| |.|||..|. ..|. | ||.|
alfavfdGhaGkGaadaakklfpkelekllkstkqddGGdniydqskllenafkevdaklkdf........eye..GatatlalvwsdGqqrylqvanvG
DSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
|| |.|.| .. |. || . . || ||| | . . | . .| . ...|..|| .|. |.|..|
dssaflsrGneslelskdhkak.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 127-283 | 3e-11 | 35.7 | In-house | 37-203 (276) | alignment | ||
Range on Protein: 127-283
Range on HMM: 37-203/276.0
GIFDGHAGSMAVDYVHHNLEFHLKFWLE--------------REHDLQIVLKNAFEDLNNKLTRYlyfhypetEYEnsGSTATVSLL-RNGN--------
..|||||| | | .. . |. .|. .| . .|...|.....|| . ||| |.|||..|. ..|.
avfdGhaGkGaadaakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdf........eye..GatatlalvwsdGeeqqqqqqr
ELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNslgKPLVNSVlTMTRSFGDVTLKRY--GVIATP
| ||.||| |.|.| .. |. || . . ||.||| | . . | . .| . ...|..|| .|. |.|..|
ylqvanvGdssaflsrGneslelskdhkat.dpeekqrikddGitlsdn...qtrinGl.avsralGdhfikelniGlisep
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 159-275 | 2.3e-10 | 33.1 | In-house | 115-241 (398) | alignment | ||
Range on Protein: 159-275
Range on HMM: 115-241/398.0
LQIVLKNAFEDLNNKLTRYLYFHYPETEYEN------SGSTATVSLLrNGNELVLANLGDSRAILCRN---G--KAKRLTNDHDPEyNTTEKERIKAAGG
.. .||.||..| . .. . .|.. .. ||..|...|. .|.|| .|| ||.||.|... | .|..|..|. . |. | ||||..
vkealkkaFlklDkdistealkklkekslreallvalsGacallali.egtelhvAntGDcravlgvqeeegsweavkLskdqtad.neeEveRikkeHP
SFTW-NSLGKPLVNSVLTMTRSFGDVTLK
. . . . . |. .| |||| .|
geesktvirngRlLgeLqPlRAFGdvryK
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 164-243 | 1e-09 | 30.7 | In-house | 141-211 (404) | alignment | ||
Range on Protein: 164-243
Range on HMM: 141-211/404.0
KNAFEDLNNKLTRYlyfhypETEYENS-GSTATVSLLrNGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyntTEKERIK
.|| .......| ...|. . | || |.|. . | .|| |||||||.|... . | .|. || ||..|..
esaflemDeqiare......reayrikGGCtalvalv.llgklYvanaGDsRailvrkdeiiplsadftPe...teRqRlq
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 184-276 | 1.2e-22 | 73.6 | In-house | 290-376 (473) | alignment | ||
Range on Protein: 184-276
Range on HMM: 290-376/473.0
ETEYENSGSTATVSLLRnGNELVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNSlgKplVNSVLTMTRSFGDVTLKR
|.. |.||.||.| ||. ...|. || ||||..|.||||| | || || . .|.|||..||| . . . || | . | .|| . |.
eepGedsGttAvvaLlk.ekklivAnaGDsRcvlsrnGkAldlslDHkPe.DevEleRiekAGGkvdedg..R..vnGGLnlsRAlGDhaYkk
|
|||||||||
subfamily_TAB1_pd | Subfamily TAB1 | 190-275 | 1.7e-09 | 29.9 | In-house | 129-213 (333) | alignment | ||
Range on Protein: 190-275
Range on HMM: 129-213/333.0
SGSTATVSLLRNgNELVLANLGDSRAILCR---NGKAKRLTNDHDPEyNTTEKERIKAAGgsFTWNSLGKPLVNSVLTMTRSFGDVTLK
|.|| | |. | |.| || |||||.|.. . | | | ||. . | | .|.| | . . . . . . ||| || ..|
gGttAvvalifn.nkLyVaNvGdsrAllvkrkesekvkqLsvdHttd.NedEllRlkdLG..ldieqikrnkrlgskentRsiGdykvk
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 202-289 | 2.1e-17 | 56.0 | In-house | 187-274 (492) | alignment | ||
Range on Protein: 202-289
Range on HMM: 187-274/492.0
GNELVLANLGDSRAILCRNGKAKRLTNDHDPeYNTTEKERIKAAGGSFTWNSlGKPLVNSVLTMTRS---FGDVTLKRyGVIATPETRSLE
| .|| |. .|.|||.|||..|| .|.| .|. |..|.. ||.. . . . ||| .|. || .|| ||. || |.|.| .
lgvlyianaGnvqAvLcreGkaiiLtreHtp.rnkkERtRvekagsvvvkse.knglvnGildttRGLGnyGdpkLkk.svipePkttsvk
|
|||||||||
subfamily_Dicty-PPM1L-like_pd | Subfamily Dicty-PPM1L-like | 205-253 | 4.8e-07 | 21.9 | In-house | 229-276 (305) | alignment | ||
Range on Protein: 205-253
Range on HMM: 229-276/305.0
LVLANLGDSRAILCRNGKAKRLTNDHDPEyNTTEKERIKAAGGSFTWNS
||.|. .|.. .|...|... | ... .| . |. |.| .. |.
lvvakanDqflvlatdGlwevlsyqdvve.evkellrdkssqkkiewdf
|