Gene TAB1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP194_AA protein Get Run
SpurP194_AA_69-393 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPM1G2_pd Subfamily PPM1G2 55-320 3.1e-19 62.0 In-house 21-231 (287) alignment 
Range on Protein: 55-320
Range on HMM: 21-231/287.0
IGYSNNQVYRQDgaRSEDHEYEDKFFHFRTEQDDYLYAIFDGYDGTYAPGFAHQGlpaelllgqlssvhddaevkrillrafvtverglfesLDHVVAER
.| |  | || .    . |  |..... . ...  |.|.|||. |. .  .| .                                      | ...|..
vgssamqGyrln..meDahilenelleksddkslalfavfDGhGGakvakyagkk.....................................likkiakk

ANLKLSLPDDVSdYELFQKYPEQMEKFHSMTaDISGGTSAIVALIHVNKLFVANVGDSRALLCTlepdnTTKVRQLSVDHTTNNQDELLRLSQLGldtNT
 ..|    . .   . | .  |.. | ...  | | |. |.|.||. .||.|||.|||||.|..     ...|..||.||  ....|  |. . |    .
ksfkegaleqil.kdafletDeellkdeklk.desaGstavvvlikeeklyvanaGDsravlss.....kgnvkalsfDhkPqeesekkriiaag...Gf

VQSNKLLGDKMATRTIGNHTVKGGYKentllCKASSEPILAEPDIIGgLDVTNMTGFLMMYSNGLS
|. |.  |     | .|... | . |      |.  . . |.||..   .... . ||..  .|. 
velnrvngnLalsralgDfefkknvk.....kkpeeqivtavPDvlv.kkldeddeflvLaCDGiW
subfamily_TAB1_pd Subfamily TAB1 60-393 1.9e-148 486.7 In-house 4-332 (333) alignment 
Range on Protein: 60-393
Range on HMM: 4-332/333.0
NQVYRqdgarSEDHEYEDKFFHFRTEQDDYLYAIFDGYDGTYAPGFAHQGLPAELLLGQLSSVHDDAEVKRILLRAFVTVERGLFESLDHVVAERANLKL
|. |.     .||||.|||.|.|.||.|..|||.||||||..|..|..| |.|||||.||.. ...||||..|.|||..|||...||.|...||...|..
nrrys.....kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekddlqs

SLPDDVSDYELFQKYPEQMEKFHSMTADISGGTSAIVALIHVNKLFVANVGDSRALLCTLEPdnTTKVRQLSVDHTTNNQDELLRLSQLGLDTNTVQSNK
.||..||.|||...|||..|........|||||.|.||||..|||.|||||||||||.. ..  ..||.||||||||.|.||||||..||||......||
qlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldieqikrnk

LLGDKMATRTIGNHTVKGGYKENTLLCKASSEPILAEPDIIGGLDVTNMTGFLMMYSNGLSQSLIEATGTSQANLD-LAYMAMAEFEVQATLSGVAQAVV
.||.|..||.||...||.|||....|..|..||..|||||.|.......|.||...|.|....| |.||....|.. .......|.| ||||..||||||
rlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdvAqavv

DKVVRRHHDTYLSEG-GRMAICQKRDDITLIVRNFN
||| |.|.|.|||..  |..||.||||.||.|..|.
dkvkrkHkdaylssaseravicrkrddmtllvlkfe
subfamily_PPM1A_pd Subfamily PPM1A 69-321 1.3e-16 53.8 In-house 23-232 (282) alignment 
Range on Protein: 69-321
Range on HMM: 23-232/282.0
RSEDHEYEDKFFHFRTEQDDYLYAIFDGYDGTYAPGFAHQGLPAELLLgqlssvhddaevkrilL---------------------RAFVTVERGLFESL
|.|  .  .   .. . .|  ..|.|||  |. .  .... |....|                                       ..|....  . |. 
rvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile................eeelkeaaleasekdevkealrqgfLaldeairels

DHVVA-ERAnlklslpddvsdyelfqkypeqmekfhsmtadisgGTSAIVALIHVNKLFVANVGDSRALLCTlepdnTTKVRQLSVDHTTNNQDELLRLS
... . ...                                   |. |...|.. ..|..||.|||||.||       .|.  |. ||  ....|  |..
tdlktadks...................................GsTavtvlvsekhliianlGDsRavlcr.....ngkaaflteDHkpsrpkEkkRie

QLGldtNTVQSNKLLGDKMATRTIGNHTVKGGYKEntllcKASSEPILAEPDIIGgLDVTNMTGFLMMYSNGLSQ
| |    .|  ... |    .|..| ...|   .      ||..  . |||..   .. ..   ||.. . |.  
qAG...GsvvvsRvnGaLAvsRalGDyeykeeeek.....kaeeqlvsaepevts.ierseeddflvlacDGiwD
subfamily_PPM1H_pd Subfamily PPM1H 70-248 4.6e-13 41.7 In-house 44-213 (404) alignment 
Range on Protein: 70-248
Range on HMM: 44-213/404.0
SEDHEYEDKFFHFRTEQDDYLYAIFDGYDGTYAPGFAHQGLPaELLLGQLSSVHDDAEVKRILLRAFVTVERGL-FESLDHVVAERANLKLSLPDDvSDY
... . . |  .. .. . .....|||. |. |   | . |  . |  .|..| .    |    . ..  ..    .| .... |.   | .|    .  
eksvtskpkekseeeklplayfglfDGhaGsgaalvaskllh.khlkekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviG.ale

ELFQKYPEQMEKFHSmTADISGGTSAIVALIHVNKLFVANVGDSRALLCtlepdNTTKVRQLSVDHTTNNQDEllRLSQL
. |..  ||... .. .  |.|| .|.|||.  .||.||| |||||.|.     .. ....|| |.| . . .  || .|
saflemDeqiarere.ayrikGGCtalvalvllgklYvanaGDsRailv.....rkdeiiplsadftPeteRq..Rlqel
PP2C_SIG_SM00331 70-389 1.4e-06 21.1 In-house 10-214 (217) alignment 
Range on Protein: 70-389
Range on HMM: 10-214/217.0
SEDHEY--EDKFFHFRTEQDDYLYAIFDGYDgtyapgfahQGLPAELLLGQLSSVHDDAEVKRillrafvTVERGLFESLDHVVAERanlklslpddvsd
.|. .   .| .. . ......|....|| .         .||.|..  .|| .. .    ..       .    ... |. .. |.             
yeeatqvsGDyydvvklnegrlllvvaDgmG.........kGlaAaaassqlrtalrellseg.......eelsqalkrlnraiyee.............

yelfqkypeqmekfhsmTADISGGTSAIVALI--HVNKLFVANVGDSRALLCTlepdNTTKVRQLSVdhttnnqdellrlsqlgldtntvqsnkllgdkm
                 . . ........||.    .|| .||.|||| .| .    .   | .|.                                  
.................keekgmfaTlllalydfssgklsyanaGdsrpyllr....dgklveilkd.................................

atrtignhtvkggyK-----------EntllckassepilaepdiiggLDVTNM----TGFLMMYSNGLSQSLIEATgTSQANLDLAYMAMAefevQATL
              .           .                     .|....      .|..|. ||     |.. . .. | ..  . .    . ..
..............vegaplGlepevs.....................vdirelelekgdllllytDGltearsekg.faeerleeiledlv....dsea

SGVAQAVVDKVVRRHHDT-YlseggrmaicqkRDDITLIV
  .||. |......  .  .            .||||..|
qelaqkiveellelakgsng............eDdiTvvv
PP2Cc_SM00332 71-389 3.4e-31 101.6 In-house 20-273 (274) alignment 
Range on Protein: 71-389
Range on HMM: 20-273/274.0
EDHEYEDKFFHFR---TEQDDYLYAIFDGYDGTYAPGFAHQGLPaELLLGQLSSVHDD--AEVKRILLRAFVTVERGLFESLDHVVAERanlklslpddv
. .. || ..       |.|  ....|||  |. .. |. . || | |  .|... |.   .|...| .||. ..  . |. .    |.           
wrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklp.ealkeelkkkkdeleddveealkkaflstdeeileeeqskelen...........

sdyelfqkypeqmekfhsmtadISGGTSAIVALIHVNKLFVANVGDSRALLCTLEPdnttkVRQLSVDHTTNNQDELLRLSQLGLdtnTVQSNKLLGDKM
                       . |..|.|||.. ..|.||||||||| ||. .      ..||||||.....||. |... |    .|. ... |. .
......................alsGstavvallkkedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkagg...vvekgrvnggla

ATRTIGNHTVKGGYkentllcKASSEPILAEPDIIgGLDVTNMTGFLMMYSNGLSQSLIEATGTSQANLDLAYMamaefeVQATLSGVAQAVVDKVVRRh
 .| .| | .|          |  .  | ||||.   ...|. . || . | || ..| . .  .  .  || .      ..   . .|. ..... || 
vsrafGdhflkknk.......klkepyitaepdvk.vvtltsedeflilaSDGlwdvlsnqevvdivrkllakg......ktndpqeaaelldeeairr.

hdtylseggrmaiCQKRDDITLIV
              ...|.|| .|
.............ggseDniTvvv
0034914 PP2C-like 72-393 2.9e-32 104.8 In-house 32-291 (295) alignment 
Range on Protein: 72-393
Range on HMM: 32-291/295.0
DHEYEDKFFHFRT----EQDDYLYAIFDGYDGTYAPGFAHQGLPAELLLG----QLSSVHDDAEVKRILLRAFVTVERGLFESLDHVvaeranlklslpd
 .. || .....     ..| .|...|||. | .|  .|.. |. .||      .|.. ...  ....| .||. ... |.| . .              
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr.............

dvsdyelfqkypeqmekfhsmTADISGGTSAIVALIHVNKLFVANVGDSRALLCtlepdNTTKVRQLSVDHTTNNQDELLRLSQLGLdtnTVQSNKLLGD
                       .. .||.|.||||. |||.|||||||||.|.     .  ...||.|||. .|..|  |. ..|    .|. . ..| 
.....................pelagsGtTavvalirgnklyvanvGDSravll.....rngelvqltvdhkpvnelererilsagg...avshgrvngv

KMATRTIGNHTVKGGYKEntllcKASSEPILAEPDIIgGLDVT-NMTGFLMMYSNGLSQSLIeatgtsqaNLDLAYMAMAEFEVQATLSGVAQAVVDKVV
 . || .| .  |  ..       ... .. ||||..  |..| .   ||.. | ||.. |         | ... ...  .. . .|. .|...|| ..
lavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls........neeivdivrsllakgldleeaaeeLvdlAl

RrhhdtylseggrmaiCQKRDDITLIVRNFN
.               . .||.|| .|  .|
a...............rgsrDNiTvvvvrln
0049733 PP2C-like 73-389 5.5e-20 64.9 In-house 16-230 (235) alignment 
Range on Protein: 73-389
Range on HMM: 16-230/235.0
HEYEDKFFHfrteqDDYLYAIFDGYDGTYAPGFAHQGLPAELLLGQLSsvHDDAEVKRILLRAFVTVERGLFESldhvvaeranlklslpddvsdyelfq
.. || ..      . .|.|..||  |  | ..| . |.  ||   |.  ..  .....| .|| .... |.|                           
kvneDavlv.....glllfavaDGhgghaagevasellvetllellle..lllldleealrkaflaaneallel..........................

kypeqmekFHSMTADISGGTSAIVALIHVNKLFVANVGDSRALLCTlepdnTTKVRQLSVDHTTNNQDELLRLSQLGLDTntvqsnKLLGDKMATRTIGN
         ..      .||.|.|||.. .||.|||||||||.|..       |..||..||. .|..|  |. ..|           .|  . || .|.
........alaspelagmgtTavvalldggklyvanvGDsrayllr.....dgklvqltedhspvnelerqriitaggav......rvpgrlaltralGd

HTVKggykentllckassepilaePDIIgGLDVTNMTgFLMMYSNGLSQSLIEATGTSQANLdlaymamaefevqATLSGVAQAVVDKVVRrhhdtylse
...|                    ||.   |....   ||...| ||.  | . .  .  .               .|. .|...|. ...         
lllk....................pdvt.vlelepgd.flllasDGlwdvlsdeeivdllrs.............ldleeaaerlvelala.........

ggrmaiCQKRDDITLIV
        .||.||..|
......rggrDNiTvvv
subfamily_PPM1K_pd Subfamily PPM1K 73-276 3.9e-15 48.7 In-house 16-182 (263) alignment 
Range on Protein: 73-276
Range on HMM: 16-182/263.0
HEYEDKFFHFRTEQDDYLYAIFDGYDGTYAPGFAHQGLpaELLLGQLSsvHDDAEVKRILLRAFVTVERGLFESLDHVVAERanlklslpddvsdyelfq
.| ||..   . ... . .|.|||. |. |  |.|. |  |  | .|   . . ... .| .||  ... |   | . |||.                  
aenedriklkeldpellyvavfdGhaGsaaadfvhdkl..ekilkrll..ekekdleivlknafeeldkklkrylefsvaea..................

kypeqmekfhsmTADISGGTSAIVALIHVNKLFVANVGDSRALLCTlepdnTTKVRQLSVDHTTNNQDELLRLSQLG--LDTNTVQSNKLLGDKMATRTI
            .   || |.... | . ..| .|..|||||.||        | ..|. ||. . ..|  |. . |  .. |...  .. |    ||..
............ellssGttatvsllrdGtelvlaslGdsrailcr.....nGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrsl

GNHTVK
|. ..|
Gdldlk
subfamily_PPM1L_pd Subfamily PPM1L 74-277 1.6e-12 40.3 In-house 18-189 (269) alignment 
Range on Protein: 74-277
Range on HMM: 18-189/269.0
EYEDKFFHFRTE---QDDYLYAIFDGYDGTYAPGFAHQGLPAELlLGQLSSVhddaevkR-------IllrafvtverglfesldhvvaeranlkLSLPD
. ||.|     .    .  ..|.|||. | .|  ||.. |. .. . .|  .                                           ..   
rmedrfeieediknktgesffavfdGhGGefaaefakdvlvkai.knkliel.......dadkentep...........................infsk

DVSDyELFQKYPEQMEKFHSmTADISgGTSAIVALIHVNKLFVANVGDSRALLCtlepDNTTKVRQLSVDHTTNNQDELLRLSQLGLDTNTVQSNKLLGD
 . | |..    . .|| .. . ||. ||.|..||.. ..| |||||||| .|.    |.. |   || ||  ..  |  |. . |       . .. | 
lltd.eilsvdekllekakr.aedia.GttalialvqesdlivanvGdsrGvly....dkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGv

KMATRTIGNHTVKG
   .|..|.. .| 
latsralGdyplkd
PPM_PTC7_SpoIIE 168-391 1.2e-11 37.8 In-house 87-228 (230) alignment 
Range on Protein: 168-391
Range on HMM: 87-228/230.0
YelfqkypeqmekfhsmtaDISGGTSAIVALIHVNK--LFVANVGDSRALLCTLEPDnttkvrqlsvdhttnnqdellrlsqlgldtntvqsnkllgdkm
.                  ..|.|..|.||||. ..  | |||.|||..||.. ..                                            
e..................psssgaTavvalidpstgklyvanaGdsppllvrddgg...........................................

atrtignhtvkggykENTLLcKASSEP-I-LAEPDIIGGLDVTNMTGFLMMYSnglSQSLIEATG-TSQANLDL--AYMAMAEFEVQATLSgvAQAVVDK
               | ... .|   | . . .  . | | |.   | | ..    .  ..||   ||. .|.   .....|   .   ||  .| .||.
...............ereri.vagglpslGilpgrvfgvlavslapGdlllly...tDGvveaepdtsdgelfgkdeflilasdglwdvls..pqelvdl

VVRRHHDTylseggrmaIC--QKRDDITLIVRN
|... ..          ..  ...|||||.| .
vrdelekp.........aaeglleDDitllvvr
subfamily_PDP_pd Subfamily PDP 169-299 7.4e-20 64.4 In-house 133-276 (398) alignment 
Range on Protein: 169-299
Range on HMM: 133-276/398.0
ELFQKYpEQMEKFHSMTADISGgTSAIVALIHVNKLFVANVGDSRALLCTLEPDNTTKVRQLSVDHTTNNQDELLRLSQLGLDTNT---VQSNKLLGDKM
| ..|  .. .  ..... .|| . |..|||. ..|.|||.||.||.|.. |.. . ....|| |.|..|..|. |. .   . .    .....|||  .
ealkkl.kekslreallvalsG.acallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLq

ATRTIGNHTVKGGY-KENTLLCK---ASSEP--------ILAEPDI
 .|  |.   |     ....| |     .||        . |||..
PlRAFGdvryKwseelqkkvlekaylkvlepkdyktPPYltaePev
PP2C Protein phosphatase 2C 171-337 4.2e-26 85.0 Pfam-A 80-230 (255) alignment 
Range on Protein: 171-337
Range on HMM: 80-230/255.0
FQKyPEQMEKFH--SMTADISGGTSAIVALIHVNKLFVANVGDSRALLCTLEPDNttkvRQLSVDHTTNNQDELLRLSQLGLDTNTvqSNKLLGDKMATR
|..  ...|.     .|.... |..|.||||  .||.|||||||||.||.   .      .|..||.....||  |....|   .    ... |    .|
fla.dtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsR

TIGNHTVKGGYkentllckasSEPILAEPDIIgGLDVTNMTGFLMMYSNGLSQSLIEATGTSQANLDLA
 .| . .| ..          .... ||||.    . |. . || . | || . | . .  . .. .| 
alGdfelkpke..........eqlvsaePdvt.svklteedefliLasdGlwdvlsdqeavdlvrsels
PP2C Protein phosphatase 2C 171-337 4.2e-26 85.0 In-house 80-230 (255) alignment 
Range on Protein: 171-337
Range on HMM: 80-230/255.0
FQKyPEQMEKFH--SMTADISGGTSAIVALIHVNKLFVANVGDSRALLCTLEPDNttkvRQLSVDHTTNNQDELLRLSQLGLDTNTvqSNKLLGDKMATR
|..  ...|.     .|.... |..|.||||  .||.|||||||||.||.   .      .|..||.....||  |....|   .    ... |    .|
fla.dtdeelksskantepsksGstavvalirgkklyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsR

TIGNHTVKGGYkentllckasSEPILAEPDIIgGLDVTNMTGFLMMYSNGLSQSLIEATGTSQANLDLA
 .| . .| ..          .... ||||.    . |. . || . | || . | . .  . .. .| 
alGdfelkpke..........eqlvsaePdvt.svklteedefliLasdGlwdvlsdqeavdlvrsels
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 172-273 6.1e-13 41.6 In-house 79-175 (255) alignment 
Range on Protein: 172-273
Range on HMM: 79-175/255.0
QKYPEQMEKFHSMTadISGGTSAIVALIHVNKLFVANVGDSRALLCtlepDNTTKVRQLSVDHTTNNQDELLRLSQLGLD-TNTVQSNKLLGDKMATRTI
. | |   ..   .  .  ||.|...||  .| ..|||||||..||    .. .  ..||.||  ....| .|.|.||    .||.. .. |    .|..
kaykeistqiserp..kfiGttaasvliiedkvyianvGdsrvvlc....qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsral

GNH
|. 
Gds
subfamily_PPM1D_pd Subfamily PPM1D 173-251 1.4e-11 37.1 In-house 96-170 (309) alignment 
Range on Protein: 173-251
Range on HMM: 96-170/309.0
KYPEQMEKFHSmTAdisgGTSAIVALIHVNKLFVANVGDSRALLCTLEP-DNTTKVRQLSVDHTTNNQDELLRLSQLGLD
..|.....  | ||    || | | .|  .||.||.||||...| . || ... . ..| .||  .. .|  |. .|| .
eWpktksglls.ta....GttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGe
PPM_PTC7 177-323 1.3e-26 86.6 In-house 86-221 (259) alignment 
Range on Protein: 177-323
Range on HMM: 86-221/259.0
QMEKFH--SMTADISGGTSAIVALIHVNKLFVANVGDSRALLCTLEPDNttkvRQLSVDHTTNNQDELLRLSQLGLDTNTVQSNKLLGDKMATRTIGNHT
 .|.     .|.....|..|.||||  .||.|||||||||.||. . .      ||..||...|.||  |....|   ..|. ... |    .|..| . 
deelksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavsRafGdfe

VKGGYKentllckaSSEPILAEPDIIgGLDVTNMTGFLMMYSNGLSQSL
 | ...        ..... |||||    . .. . || ..| || . .
lkpket........eeqlvsaePdis.stkideedefliLasdGlwdvv
subfamily_PPM1E_pd Subfamily PPM1E 182-276 1e-09 31.0 In-house 94-183 (265) alignment 
Range on Protein: 182-276
Range on HMM: 94-183/265.0
HSMTADISGGTSAIVALIHVNKLFVANVGDSRALLCtlepdNTTKVRQLSVDHTTNNQDELLRLSQLGLDTNTVQSNKLLGDKMATRTIGNHTVK
...   . .|. |.|.||. ..|.|| .|||.|||.     . ....||   |  ...||  |. ..|     .   .  |    .|.||. . |
kaereklksGstavvvliekdqlyvaWlGDsqallv.....rkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 184-249 6.2e-08 25.5 In-house 79-145 (292) alignment 
Range on Protein: 184-249
Range on HMM: 79-145/292.0
MTADISGGTSAIVALIHVN-KLFVANVGDSRALLCTLEPDNTTKVRQLSVDHTTNNQDELLRLSQLG
. |  |..|... | .. . .|..||||||||||      .  ... || ||  .. ||  |. . |
idaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraG
subfamily_PPM1G_pd Subfamily PPM1G 189-359 5.2e-14 45.1 In-house 295-446 (473) alignment 
Range on Protein: 189-359
Range on HMM: 295-446/473.0
SGGTSAIVALIHVNKLFVANVGDSRALLCTLepdntTKVRQLSVDHTTNNQDELLRLSQLGLDTNtvQSNKLLGDKMATRTIGNHTvkggYKENTLLCKA
. || |.|||.. .||.|||.||||. |.        |  .||.||  ... || |. . |   .  .  .. |     | .|.|.    ||.|. | . 
dsGttAvvaLlkekklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvd..edgRvnGGLnlsRAlGDha....YkkneeLplk

sSEPILAEPDIIgGLDVTNMTGFLMMYSNGLSQSLieatgTSQANLDLAYMAMAEFEVQaTLSGVAQAVVD
    | | |||   | .|.   ||.. ..|.  ..     .||  .|     ... | . .|| . ....|
.eqmisAlPDik.vltlteedeFlvlAcDGiWnvm.....esqevvdfvraklkkgees.vlseiveeLlD
subfamily_KAPP-like_pd Subfamily KAPP-like 189-320 1.5e-08 27.0 In-house 99-216 (266) alignment 
Range on Protein: 189-320
Range on HMM: 99-216/266.0
SGGTSAIVALIHV----NKLFVANVGDSRALLCTlepDNTTkvRQLSVDHTTNNQDELLRLSQLGLDTNTVQSnKlLGDKMATRTIGNHTVKggyKENtl
  |..| .||.        | ||||||| |.|.     | .   .|| || .....|  |. . |.     |. . .   . .|..|.| .|   . |  
yeGatatlalvwsdGqqrylqvanvGdssaflsr...Gnes..lelskdhkakdpeekqrikddGitlsdnqt.r.inGlavsralGdhfik...eln..

lCKASSEPILAEPdiiggLDVTNMTGFLMMYSNGLS
 .  .||| ....     . .| .  ||.. |.|| 
.iGlisepyvsnr.....illtpfdkflivasdGlw
subfamily_ILKAP_pd Subfamily ILKAP 190-276 1.8e-11 36.7 In-house 113-197 (293) alignment 
Range on Protein: 190-276
Range on HMM: 113-197/293.0
GGTSAIVALIHVNKLFVANVGDSRALLCTLEPDNT-TKVRQLSVDHTTNNQDELLRLSQLGldtNTVQSNKLLGDKMATRTIGNHTVK
 |. |.| |.  | |.|||.|||.|.|.  ... . ... .|..|||. ...|  |. . |    .|. ...||    .|.||.   |
dGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGdgrfk
subfamily_PP2D1_pd Subfamily PP2D1 190-325 4.2e-08 25.3 In-house 176-295 (492) alignment 
Range on Protein: 190-325
Range on HMM: 176-295/492.0
GGTSAIVALIHVNKLFVANVGDSRALLCTlepdNtTKVRQLSVDHTTNNQDELLRLSQLGLDTNTVQ-SNKLLGDKMATRTIGNHtvkGgykeNTLLCKA
   .  | |.    |..||.|. .|.||     .  |  .|  .||..|. |  |... |      .   .  |   .|| .||.   |    .. | |.
esngsevhleelgvlyianaGnvqAvLcr....e.GkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny...G....dpkLkks

ssepILAEPDIIgGLDVTNMTGFLMMYSNGLSQSLIE
    .. || ..    ... . ||.. |||| . | |
....vipePktt.svkldeaaqflvlAsnGlWevlse
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 203-320 1.6e-07 23.5 In-house 127-226 (276) alignment 
Range on Protein: 203-320
Range on HMM: 127-226/276.0
KLFVANVGDSRALLCTlepDNTTkvRQLSVDHTTNNQDELLRLSQLGLDTNTVQSnKlLGDKMATRTIGNHTVKggyKENtllCKASSEPILAEPdiigg
 | ||||||| |.|.     | .   .|| || ... .|  |. . |.     |. . .   . .|..|.| .|   . |   .  .||| ....     
ylqvanvGdssaflsr...Gnes..lelskdhkatdpeekqrikddGitlsdnqt.r.inGlavsralGdhfik...eln...iGlisepyvsnr.....

LDVTNMTGFLMMYSNGLS
. .| .  ||.. |.|| 
illtpfdkflivasdGlw