Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPP2C_pd | Subfamily PPP2C | 11-299 | 1.4e-191 | 627.9 | In-house | 2-290 (290) | alignment | ||
Range on Protein: 11-299
Range on HMM: 2-290/290.0
KELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRF
|.|||.|.||..||||||..||.|||||||.||.||||||||||||||||||||||||.|||.||||||||||||.||||||||||||||.||||||||.
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry
PNRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRG
..||||||||||||||||||||||||||||||.||||||||||||||||||||.|||||||||||||||||.||.||||||||||||.||||||||||||
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrg
GWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPRRG
||||||||||||||.||||.||..|||||..||||||||||||.||||||||||||||||||||||||.|||| |||.|||||||||||
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprrg
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 12-296 | 5e-150 | 491.5 | In-house | 2-286 (288) | alignment | ||
Range on Protein: 12-296
Range on HMM: 2-286/288.0
ELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFP
.||. |.||..|. ..|..||.||.||.|.| .|||||.|..|||||||.||||.||.|||..||. |.|||||.||.||||.||||| ||.|||||.|
dldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvryp
NRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRGG
.|||..||||||||||||||||||||||||. |||.| |..||||.|.|..||.|||.||||||||.|||.|||.|| ||||||||.||||||||.| |
dritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaeg
WGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAP
|..||||||| ||.|..|.||..|...|..||||||||||.. ...|.|..||||||||||| |||.|||. |.. | |. |.
wavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaa
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 12-293 | 3e-139 | 456.1 | In-house | 1-282 (290) | alignment | ||
Range on Protein: 12-293
Range on HMM: 1-282/290.0
ELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFP
|||||| ..|| | ||..|.||.. ..||..||||| |..|||||||.||||.||.|||| ||. |||.|.|.||.|||||||.||...|..||...|
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp
NRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRGG
.|||.|||||||||||||||||||||.|||| |.|||.|..|| |...|..|.|..|.|||||| . |||.|| ..| ||.||.|..|||.||||.|
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvet
WGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFD
| .||||||| ||. ....|.|.| | |..||||||.||... | ..||..||||||||||| |.|..|.| . .. |.
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfk
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 13-297 | 8.4e-132 | 432.0 | In-house | 1-298 (300) | alignment | ||
Range on Protein: 13-297
Range on HMM: 1-298/300.0
LDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPN
||. . ||. .. | | ||.|..| |||| .||||.|...|||| |||||||.|..|.|.|||. |||||||.|||||||.|||||.|||..||.|.|
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps
RITILRGNHESRQITQVYGFYDECLRKY-GNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPD----
|||.||||||||||||||||| |||||| ||..||||.|..|||| |.|..| .|.|.|||||||. ..| |. |||..|||.|| ..|||||||.
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn
------DRGG--WGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPR
|| | . .|.|||||..|.|. |.| .|| . . |||||..|||. | . |..|||||||||||.|.|.|| . ... | .. ||.
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeape
|
|||||||||
0045823 | Metallo-dependent phosphatases | 10-297 | 1e-120 | 396.5 | In-house | 27-326 (473) | alignment | ||
Range on Protein: 10-297
Range on HMM: 27-326/473.0
PKELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVR
. ||..| | ...|.|. ...|...|||.|..|.|..|.. ...|.||.|||..||..|... | |.....|.||.||||..|.|.. || |||..
lldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkik
FPNRITILRGNHESRQITQVYGFYDECLRKYgNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDR
.|.....||||||.|.....|||.||.|.|| . .....| .....|||.|...|.|.. ||||||....|| ||...| .|.|..|...|||||||..
ypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed
GG--------WGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRN------VVTIFSAPNYCYRCGNQAAIMELDDGLkYTFLQFDPA
| .| |||||||.||.|. |.| ..|||.|. |.|. |.|||....|.. ..|.|||||||.|.|| ||....|..| ..| ||||.
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdps
PR
|
ph
|
|||||||||
PPP_3 | 26-292 | 2.7e-119 | 390.1 | In-house | 2-269 (271) | alignment | |||
Range on Protein: 26-292
Range on HMM: 2-269/271.0
LEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQ
|.||..|.|..|.||.|..|||..|.. |||||||.|||..||.|||..||.||.|.|||.|||||||..|.|.. ||.|||...|.....|||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
ITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDL-LWSDPDDRGGWGISPRGAGYTFG
|..||||..|.|.|.|. .|.|.....|..|||.||.|......||||||||..||.|..|.| .|||.||...|| |.|||....|.. |.||||..||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg
QDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQF
.|..|.|...| |.|. |||.|..|||. .||..|||.|||||||.|..|..||..|.. |...| |.
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql
|
|||||||||
PPP_1 | 27-281 | 1.4e-117 | 384.6 | In-house | 2-264 (264) | alignment | |||
Range on Protein: 27-281
Range on HMM: 2-264/264.0
EENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQI
||.....|..|.||||..|.|..||. ..|||||.||||.||..||..||.||.|||||.|||||||..|||.. ||.|||...|.....|||||||||.
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv
TQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDL--------LWSDPDDRGGWGISPRG
|.||||..|.|.|... ...|..||.||.|||.||.|..|...||||||..|.||.|| ..| .|||.||..||| |..|....... |.||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG
AGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMEL
|||.||.|..|.|...|.|.|. |||....|||.....|.|||||||.||.....|..|...|
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl
|
|||||||||
0049330 | Metallo-dependent phosphatases | 11-298 | 2.9e-113 | 370.9 | In-house | 15-302 (309) | alignment | ||
Range on Protein: 11-298
Range on HMM: 15-302/309.0
KELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRF
. ||..| .| .|.|.|. ...|..||||.| .|.|..|.. ...|.||.|||..||..|... | |.....|.||.||||..|.|.. || |||...
slldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalklly
PNRITILRGNHESRQITQVYGFYDECLRKYGnPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPD-DR
|.....||||||.|.....|||.||.||||| ...|..|.|....|||.|...|.|.| ||||||.. .||.||.|.| .|.|..|..||||||||. .|
pdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpir
GGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPRR
|.. .|||.|..|| .. |.| . |||.|. |.|..|..|| ...|....|.|||||||.|.||..|..|.|..|...||.|.|.|.
egfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpll
|
|||||||||
PP2Ac_SM00156 | 27-295 | 2.3e-111 | 364.1 | In-house | 2-270 (271) | alignment | |||
Range on Protein: 27-295
Range on HMM: 2-270/271.0
EENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQI
....|..|.|..||.|.||.|. ||. ||||.||.|||..||..|.. .|..|...|.|.|||||||..|.|...||.|||...|.....|||||||...
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv
TQVYGFYDECLRKYgNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDP-DDRGGWGISPRGAGYTFGQ
...|||..|. ||| . .... |...|..|||.|||| .|.|.||||||.. .||.||.|.| .| |.||...||||||| .. |. .| ||....||.
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge
DISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPA
|. ..| ..| | |. |||..|.|||....|...||||||||||....|.||.......|| .. |....
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
|
|||||||||
0053225 | Metallo-dependent phosphatases | 11-296 | 4.8e-109 | 357.1 | In-house | 7-292 (293) | alignment | ||
Range on Protein: 11-296
Range on HMM: 7-292/293.0
KELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRF
||..| | .|.| |. .. |...|||.|..|.|..|.. ...|.||.||...||..|... | |.....|.||.||||..|.|.. || |||...
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly
PNRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRG
|.....||||||.......|||.||.|||||. ..|....|....|||.||..|.|.. ||||||....||.||...| ...|.||...||||||||..
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws
GWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAP
||..|.||.|..|| .. ..| ..|||.|. |.||.|..|| ...|...||.||||||..|.||..|...||.||...| .|.| .
gwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 24-292 | 1.2e-105 | 345.8 | In-house | 8-276 (282) | alignment | ||
Range on Protein: 24-292
Range on HMM: 8-276/282.0
KQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHES
.|.|.....|..||.|.| ... . |.. ||...||.|||..||. || ..| |..||||.||||||| |.||. ||.|.|...|... .|||||||
vklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhes
RQITQVYGFYDECLRKYGNPnVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDD-RGGWGISPRGAGYT
.|...||||||| |.|.. .|| ||| |..|||.|||| .|.|.||||||... |..||.. | |||..| .|||||||||. . ||. . || .|
asinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsft
FGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQF
||.|. |.| ..| | |. ||||.| .||.. .|..||.||||||| . .|..|....|. |. .| .
fgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqil
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 17-296 | 7.9e-100 | 326.7 | In-house | 15-295 (298) | alignment | ||
Range on Protein: 17-296
Range on HMM: 15-295/298.0
IAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITI
... . .|...|..|..|.|.||..... . . ||. |..||||.|||. ||. || .| ||.||||.||||||| ...|.. ||.| ||..||.. .
lsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffl
LRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDD-RGGWGIS
|||||| .| .|||||.|| |.| . .... | |.|. ||||||. |.|.|.|||||. . .||..|.| | .. ..| ||||.||.. || .
lrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwaen
PRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAP
||....||.| ... .. . || ||||.| .||.. ....|||||||.|| . | ||.|..|. |. .| . |.
srGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpek
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 24-298 | 1.6e-89 | 293.1 | In-house | 22-297 (299) | alignment | ||
Range on Protein: 24-298
Range on HMM: 22-297/299.0
KQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHES
| ..|.....||. ||. . ... . ||. |. ||||.|||. ||. .| . | ||.|.||.||||||| .|...||.. |...|.|. .||||||
ksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhec
RQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYT
| .|||||.|| ..| .| | | |...||| |. ..|.|.|||||| ..||| .| | | |. | ||||.|||. .| || |
painrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyv
FGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPRR
||||. .. .. .. ||.||||.| .||.. ....||||||| || . | ||||..|. | || . |.|..
fgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpks
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 23-283 | 4.2e-89 | 292.4 | In-house | 38-311 (452) | alignment | ||
Range on Protein: 23-283
Range on HMM: 38-311/452.0
CKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHE
.|||... .. |.| .||..|... ||. |.||.||.||||.||..|| .||. .|.|||.||||||||.|.|.| | |||. .|... .||||||
egrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhe
SRQITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRGGWGI--------
.| .|. . | .|| ||.. .|.. ... || |||.||...| .|.|||||| | .|| |..|||..|.|. ||.|||||||| .. |
crhlteyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpn
SPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHD------RNVVTIFSAPNYCYRCGNQAAIMELDD
|.|| | .. . .| ..| | . |||. .||. .. ..|.||||||. |.||......
svrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyen
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 23-295 | 1.3e-87 | 286.5 | In-house | 5-275 (280) | alignment | ||
Range on Protein: 23-295
Range on HMM: 5-275/280.0
CkqLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHE
| ..| ..... || |..|. .. . ||..||.||||.|||. ||. || . ||.||||.||||||| . .| . ||.| |||.||.. |||||||
c..ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhe
SRQITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPD-DRGGWGISPRGAGY
.| . |||.||. |.| . .... | .|.| |||.||| |.|.|.|||||. . .||... | | . ..| ||||.||. . ||. ..||. .
visinrkygfkdevkrrysl.alynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsv
TFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPA
||... .. . . |. | ||.| .||.. |...||.||||.|. |.||.. .|..|. .| . ||
ifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 13-294 | 3.1e-85 | 279.0 | In-house | 21-308 (322) | alignment | ||
Range on Protein: 13-294
Range on HMM: 21-308/322.0
LDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCP----VTVCGDVHGQFHDLMELFRIGGK-SPDTNYLFMGDYVDRGYYSVETVSLLVALK
... . .... |.|.. . .. .|||||.... . |.. . .|||||.||||.||...|.. |. |.. ||| ||.|||| .|||.. .|...|
vkellelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfk
VRFPNRITILRGNHESRQITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSI-DTLDHIRSLDRLQEVPHEGPMCDLLWSDP
. .||.. . |||||| .. ..||| .|. || . .| . ||..|..|||. ... ... .|||| . |||..| .|| .. |.|| ...||||||
llyPnhfflsrGnhesdnmnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdp
DDRGGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMEL-DDGLKYTFLQFDP
... | . | || | .|| |....| ..|.|.|. |.|.. .|||. || ...|.||||||| . ||..|...| .| || .| .|.
qeanGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfea
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 23-293 | 1.6e-84 | 276.7 | In-house | 4-281 (284) | alignment | ||
Range on Protein: 23-293
Range on HMM: 4-281/284.0
CKQ-LEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKS------PDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRIT
|.. |.|... .|| .|.||. .|. .|...||...||.|||| ||. |. . | ...|||.||||||| .|.| ..|| |.|...|....
cqkllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvf
ILRGNHESRQITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDR-GGWGI
.|||||||| . . |||| || ..| . .... | | .||.|.|. .|.|.|||.| . |. . |.| ..| | ..|| |.||. . |.
llrgnhesrpvnmqygfyleckkryse.alyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegyke
SPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFD
|||||| .||.. ..|... | || ||||.||.||.. ||..||||||| || . | ||....|. | .| .
sprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlk
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 18-294 | 2.8e-82 | 269.6 | In-house | 17-293 (300) | alignment | ||
Range on Protein: 18-294
Range on HMM: 17-293/300.0
AKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITIL
|| |..... ..| ||.||. . .. |. .| . ||||||. ||. || | | .||||.||||||| |.||. ||.. |...|. . .|
akrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffll
RGNHESRQITQVYGFYDECLRKyGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDR-GGWGISP
||||| ..|.|||||||| |. | ..|| | | |. |||.|.| |.|||.|||||| ....| || . | .|| | . ||||||| | |
rgnhecanvtrvygfydeckrr.cnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewedne
RGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDP
|| | . . ..| . |. || ||| .| .||.. ||..||.||||||| | |.| . .|| .| .||
rgvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldp
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 26-297 | 5e-81 | 265.0 | In-house | 8-279 (281) | alignment | ||
Range on Protein: 26-297
Range on HMM: 8-279/281.0
LEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQ
. .....|. ... ..|.|... |.. |..| ||.|.||.|| .|| . |. |.. ..|.||||||| |.|.. || .||.|...|| .|||||| .
ytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheias
ITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRG-GWGISPRGAGYTFG
. ..|||| || ||| ..| | |. ||..||.. .. |.|||||| . .||..| . . .. | . ||||.|||... .| | ||...|||
vnkiygfyvecvtkyGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfG
QDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPR
... .. . .. |. ||||.|..||. |...|.||.|||| | ||.. .|. |. ..... ||.
knvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpase
|
|||||||||
PPP_2 | 55-246 | 3.1e-80 | 261.6 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 55-246
Range on HMM: 1-197/198.0
VTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDLFD
||||||.|||..||..||. |..||...|||.|||||||..|.|.. ||.|||...|.....|||||||.....||||..|.|.|.|. .|.|.....|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
YLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDL-----LWSDPDDRGGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQL
.|||.||.|......|||||..|..||.|.. .| .|.|.||...|| |.......... | ||||..||.|..|.. ..| |.|. |||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 23-292 | 5.6e-78 | 255.2 | In-house | 20-292 (297) | alignment | ||
Range on Protein: 23-292
Range on HMM: 20-292/297.0
CKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHE
.| . |. | .| . | ... .. .. ||..|. ||||.|||| ||. ||. || | .||||.||||||| .|.||. ||.| ||.|| . .||||||
skviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhe
SRQITQVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP---SIDTLDHIRSLDRLQEVpHEGPMCDLLWSDPD-DRGGWGISPRG
. .|||||.|| ..| .. | |.|..|||| |. .|.|.|||||| ||| .| ..| .| .|. ..||||.|| |. ||
cefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrg
AGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQF
|| ||.| . . | || ||||.| .||.. |..||||||| || . | ||.| |. |. .| .
agcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeil
|
|||||||||
PPP_4 | 55-246 | 7e-76 | 247.7 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 55-246
Range on HMM: 1-196/197.0
VTVCGDVHGQFHDL-MELFRIGGKSP-DTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKyGNPNVWKYFTDL
|||.||.|||..|| ..|...||. . ...|.|.|||||||..|.|.. ||.|||...|.....|||||||......|||..|.|.| . ...|...|.
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVP-HEGPMCDL-LWSDPD-DRGGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQL
||.|||.||.|......|||||.....||.|. ..| .|.| .|. ..|| ||||| . |. | ||||..||.|. |.| ..|.| |. |.|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 24-294 | 1.5e-75 | 246.8 | In-house | 8-281 (287) | alignment | ||
Range on Protein: 24-294
Range on HMM: 8-281/287.0
KQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHES
. ...... .. ||..|.| . . ||. |.|..||.|||..||. .| |..|...|||.||||||| |.| . || .||...|... .||||||
dafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhev
RQITQVYGFYDECLRKYGnPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQE--VPHEGPMCDLLWSDPDDRgGWGIS---PRG
..| ..|||..| ||.. ...| | |.|..||| | |. .|.|.|||.|| ...|| ...| . . .|| . ||||.||. .. |.
kkinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd.aktfelnkira
AGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDP
||. ... .. .. |. |||... |||.. |...||.|||| |. . | .|.. ... |. .| .. |
isvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp
|
|||||||||
PPP_5_Dcr2 | 55-246 | 8e-75 | 244.2 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 55-246
Range on HMM: 1-198/199.0
VTVCGDVHGQFHDL-MELFRIG-GKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKYGNPNVWKYFTDL
||||||.|||..|| ..||. | .|....|.|.|||||||..|.|.. ||.|||...|.....||||||..|....|||..|.|.||.. ...|...|.
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVP-HEGPMCDL-LWSDPD-DRGG-WGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQL
||.|||.||.|......||||||.|....... ..| .|.| ..| ..|| ||||| . | . | ||||..||.|. |.| ..|.| |. |.|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 28-294 | 9.8e-74 | 241.3 | In-house | 5-273 (284) | alignment | ||
Range on Protein: 28-294
Range on HMM: 5-273/284.0
ENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQIT
..|. | .| ... .. . ||. |. .|||.|||| ||. || | .||||.||||||| . .||. ||.| || |||.. .|||||| |
pedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslin
QVYGFYDECLRKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPM-CDLLWSDPDD-RGGWGISPRGAGYTFGQ
..||||.|| |.| .| |.. | .| .|||||| .|.|.|||.| .. . ..|.. | . | . |.||||| . . || || | ||
kiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgs
DISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDP
| .. . || ||||.| .||.. .| .||||||| || . | ||.| .. | .|. . |
dalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrp
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 80-295 | 1.2e-72 | 237.8 | In-house | 100-315 (317) | alignment | ||
Range on Protein: 80-295
Range on HMM: 100-315/317.0
DTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKYGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDT
.|||.||||||| .|.| |.||.|||...|.....|||||||| . . |||| |. ..| . .... | | |||.|.|. .|.|.|||.| ..
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelld
LDHIRSLDRLQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAI
|. . |.| ..| | ..|| |.||| . |. |.|||| ||.. ..|... | || ||||.|..||.. ||..|||||||.|| . | ||.
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav
MELDDGLKYTFLQFDPA
...|. || .. . |
lsvdkklkisinvlrpe
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 35-296 | 4.6e-69 | 226.0 | In-house | 15-276 (280) | alignment | ||
Range on Protein: 35-296
Range on HMM: 15-276/280.0
CEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYD
. .. .|||. | ..|. | ||.| |..|. || . |. |. . .|.||||||| .| . ||..||.|. .|| .||||||. . ..||||
irmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyv
ECLRKYGNPnVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDRG-GWGISPRGAGYTFGQDISENFNH
|| ||| .| | |. .|...|. ...|.|||||| . || || . | | | . ||||||| ..| || | || | ||. . |. .
ecqykygvg.lwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvveqack
NNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAP
. . |. ||||.| .||. | ..|.|| |||| . | ||.. |. |. .| |. | |
sleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlippp
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 22-294 | 5.7e-67 | 218.7 | In-house | 12-288 (290) | alignment | ||
Range on Protein: 22-294
Range on HMM: 12-288/290.0
DCKQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNH
. ...... .. ||..|.| . ||. |... ||.|||. .|.. | |. |. ..||.||||||| |.| || .|.|..... .|||||
vldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnh
ESRQITQVYGFYDECLRKYGnPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDR--LQEVPHEGPMCDLLWSDPDD--RGGWGI-SP
| |.. ..|||..| || | ..|| . |.|. |.| | |. .|.|.|||.|. |.. . ...| . . .|| . ||||.||. .
evrkvnrlygfkeelarkrg.srlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkq
RGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDP
|. ||.. ... .. .| |. |||.. ||.|. |...||.|||| |. . | ||... . |. .. . |
raisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkp
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 28-298 | 7.8e-67 | 218.6 | In-house | 22-295 (307) | alignment | ||
Range on Protein: 28-298
Range on HMM: 22-295/307.0
ENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQIT
....|. .|. ..| | . .. |. | ||.|||| ||...| . |. |.| |.| ||||||| |.|.. ||.. |. .|. | .|||||| ..
keefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvn
QVYGFYDECLRK---YGNpNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTF
. ||||.||. |. ..| | |. ||..||. .|.|.||||||.. || .| . | | . |.||.||| | | ||.|.||
kkygfyeecvtsipkcge.eiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftf
GQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPAPRR
| .. .. . |. |. ||||....|| |...|||||| || | ... .|. | . | |.
gtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpesen
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 25-286 | 1.1e-58 | 191.8 | In-house | 5-291 (302) | alignment | ||
Range on Protein: 25-286
Range on HMM: 5-291/302.0
QLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSP-----------DTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNR
....... |.|. |||..|... |. |||. ||.||||.||. .. .. ..|.|||||||. |.| ..|. |||| .|..
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptn
ITILRGNHESRQITQVYGFYDECLRKYGNPN---VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDR-LQEVPHEGPMCDLLWSDPDDR
.||||||.. | ||| .| ..|. . .|. | . | ..||.||| .|.|.|||.|| ...|..|....| |.|| .. |||..|| |
yillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldv
GGWGISPRGAGYTFG--QDISENFN--------HNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLK
. . .. |.. ...| || .. .| |. |||| . ||... |....||||||.| |. |....| |
qllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 24-286 | 1.6e-58 | 191.3 | In-house | 5-292 (302) | alignment | ||
Range on Protein: 24-286
Range on HMM: 5-292/302.0
KQLEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSP-----------DTNYLFMGDYVDRGYYSVETVSLLVALKVRFPN
|....... |.|. |||..|... |. |||. ||.||||.||. .. .. ..|.|||||||. |.| ..|. |||| .|.
keysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt
RITILRGNHESRQITQVYGFYDECLRKYGNPN---VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDR-LQEVPHEGPMCDLLWSDPDD
. .||||||.. | ||| .| ..|. . .|. | . | ..||.||| .|.|.|||.|| ...|..|....| |.|| .. |||..|| |
nyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpld
RGGWGISPRGAGYTFG--QDISENFN--------HNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLK
. . .. |.. ...| || .. .| |. |||| . ||... |....||||||.| |. |....| |
vqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 49-294 | 4.7e-58 | 189.9 | In-house | 3-255 (263) | alignment | ||
Range on Protein: 49-294
Range on HMM: 3-255/263.0
QEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKYGNPN----
|...|. .||| |||. ||. .| | . |.|||.||||||| .|.| . ||..||. .| .. .|||||| . | . |||. | ... .
lelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyes
VWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSLDRLQEVPHEGPM-CDLLWSDPDDrGGWGISP---RGAGYTFGQDISENFNHNNGLTLV
|...| ..| |.|| |.| .|.|.|||.|| . .|| ||.. | . |. |||||.||. |. | | ||. ... . . |.
vynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpek.dakgfepnkiraisnvfgkkevddlckrldidli
SRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDP
||||.| || . || ..|.||| | | ||.. .. |. .|.|. |
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkp
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 82-297 | 3.3e-56 | 183.8 | In-house | 121-336 (339) | alignment | ||
Range on Protein: 82-297
Range on HMM: 121-336/339.0
NYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKYgNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLD
|||.||||||| .|.| | || |||. .|.|| .|||||||| . |||| | .| . .... | ..|. .|. |... |.|.|||.| . ...
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyry.daqlyecfqnmfnvfpfcavinntimcmhggisehltsfn
HIRSLDRLQEVPHEGPMCDLLWSDPDD-RGGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIME
.. . | |.| | . || |.||| |. | ||| . || | .. | .| | ||.| .||.. | .|||||||||| . | ||..
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
LDDGLKYTFLQFDPAPR
.| || . | | |
idkklkisinvfrpesr
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 32-281 | 1e-53 | 175.6 | In-house | 3-275 (290) | alignment | ||
Range on Protein: 32-281
Range on HMM: 3-275/290.0
KNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLM----ELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRFPNRITILRGNHESRQIT
||..| . | .| .. |.| |. | ||.||...||. |.|.| . ...||.||||||| .||| .. |.|||| .| .. .|||||| . ..
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq
QVYGFYDECLRKYGNP--NVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRSL----DRLQEVPHEGPM-CDLLWSDPDDR-----------
. . .. |. |.|. .||. |.. ||.|||.| .| ..|| |.|. .| | .| .. .||.. . |. |.|||||..
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl
--GGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRcGNQAAIMEL
| . || |. |..| |.| ..|.| | |||. .|.. .. ..|.||. .|| |.||.. .
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs.sneaalilv
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 54-246 | 5.6e-45 | 147.1 | Pfam-A | 2-198 (200) | alignment | ||
Range on Protein: 54-246
Range on HMM: 2-198/200.0
PVTVCGDVHGQFHDL----MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVSLL--VALKVRFPNRITILRGNHESRQITQVYGFYDECL----------
...|.||.||...|| ..|..|..... ...||.||.|||| .| || || .||...|... |||||||......|||..|.|
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
-----------------------RKYGNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIrsldrlqevphegpmcdllwsdpddrggwgi
......... .. . |..||| |||||.|.. ||.||.| .. | |
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
sprgAGYTFGQDISENFNHNNGLTLVSRAHQL
... || | |.. ..|..|| |.|.
....gselfgpdalekllekygvdlvlrGHtH
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 8-189 | 7.4e-40 | 129.8 | In-house | 15-202 (383) | alignment | ||
Range on Protein: 8-189
Range on HMM: 15-202/383.0
IEPKELDKWIAKLEDCKQLEENNVKNLCEKAKELLSQESNVQEVKC----PVTVCGDVHGQFHDLMELF-RIGGKSPDTNYLFMGDYVDRGYYSVETVSL
....|..| | .. |.| . | .. .||. | | |...|. ||||||.||.. ||. .. . | |.. .|.| ||.|||| ||| . .
ltkdeveklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveilli
LVALKVRFPNRITILRGNHESRQITQVYGFYDECLRKY--GNPNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDtLDHIRSLDRL
|.|| . .|. . . ||||| . ||| | || . .. . . |.| .|||..|.| .|. .|||.| . | |. . ...|
llalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktd.lelldkiers
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 198-295 | 3.2e-22 | 71.8 | In-house | 237-335 (383) | alignment | ||
Range on Protein: 198-295
Range on HMM: 237-335/383.0
MCDLLWSDPDD-RGGWGISPRGAGYTFGQDISENFNHNNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDGLKYTFLQFDPA
. |.||||| .| . . ||.| || |..... .. .|.|. |.|. .|||...||..|.||||| || |. | . | . |. ..|. .
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqas
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 24-76 | 2.7e-13 | 42.8 | In-house | 6-59 (317) | alignment | ||
Range on Protein: 24-76
Range on HMM: 6-59/317.0
KQ-LEENNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGG
.. ..|... .|| .|.||. .| |...|||..||.||||.||. |. . |
qdlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
|
|||||||||
subfamily_YNL217W_pd | Subfamily YNL217W | 55-127 | 3.4e-09 | 29.5 | In-house | 12-80 (235) | alignment | ||
Range on Protein: 55-127
Range on HMM: 12-80/235.0
VTVCGDVHGQFHDLMELFR--IGGKSPDTNYLFMGDYVDRGYYSVETVSLLvalkvrFPNRITILRGNHESRQIT
. | ||||| . .|.||. |||| .. ...|| ...| |||.||.. . ..|||| .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvll
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 29-76 | 4.1e-08 | 25.7 | In-house | 14-61 (339) | alignment | ||
Range on Protein: 29-76
Range on HMM: 14-61/339.0
NNVKNLCEKAKELLSQESNVQEVKCPVTVCGDVHGQFHDLMELFRIGG
.. .|| .|.||. | . ....|. | ||.|||| ||. .. . |
aelaelchrareliwsepiflkleapicvmgdihgqfddllamldmng
|