Gene PPP5C-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP5C
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP180_AA protein Get Run
AqueP180_AA_5-63 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP5C_pd Subfamily PPP5C 2-63 5.2e-27 87.7 In-house 118-180 (322) alignment
Range on Protein: 2-63
Range on HMM: 118-180/322.0
TFCVVHVNYL-IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.| ... | . .  |||| ..||..||||||||.||. |.|||||||||||||||||..||||
gfkllyPnhfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlv

PPP_1 9-63 3.4e-18 58.9 In-house 87-143 (264) alignment
Range on Protein: 9-63
Range on HMM: 87-143/264.0
N-YLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.   .  ||||  .....|||. ||. |||. .. ...|.||..|||| .||.|.|.
kelfllRGNHEsrqvtkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekili

PP2Ac_SM00156 9-63 7.4e-18 57.5 In-house 88-142 (271) alignment
Range on Protein: 9-63
Range on HMM: 88-142/271.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.. .  ||||   .|..|||| ||| ||. .. . |.|.|..|||| ..|.|.|.
kvvLLRGnHEsssvnkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilc

PPP_3 9-63 1.4e-17 56.6 In-house 89-144 (271) alignment
Range on Protein: 9-63
Range on HMM: 89-144/271.0
NYLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.  .  ||||  ..|..|||. ||. ||.. |. . ..|||..||||..||.||||
evhLlRGnhEsrqinkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlv

PPP_2 9-63 5e-17 55.2 In-house 59-114 (198) alignment
Range on Protein: 9-63
Range on HMM: 59-114/198.0
NYLIFLGNHELITMNQMYGFEGEVK-KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.  .  ||||  ..|..|||. ||. ||.. |. . ..|||..||||..||.||||
evhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfelLplaalidekvlv

PPP_4 7-63 2.3e-16 53.4 In-house 59-115 (197) alignment
Range on Protein: 7-63
Range on HMM: 59-115/197.0
HVNYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
  .. .  ||||   .|..|||. ||..|.. .. . ...||..||||..||.||||
pkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvfdllplaalidekvlv

subfamily_PPP1C_pd Subfamily PPP1C 11-62 3.2e-16 52.3 In-house 99-150 (282) alignment
Range on Protein: 11-62
Range on HMM: 99-150/282.0
LIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
 .  ||||   .|..|||  |.|..|. |.   ||.|||.|||| ..|.|.|
fllrGnhesasinriyGfydeckrrysiklWktftdvfnclPlaalvdekil

PPP_5_Dcr2 6-63 6.7e-16 51.8 In-house 58-116 (199) alignment
Range on Protein: 6-63
Range on HMM: 58-116/199.0
VHVNYLIFLGNHELITMNQMYGFEGEVKKKYNGK-MADLFTEVFNWLPLAHVIDNKVLV
.  .. .  ||||   .|..|||. ||..||.|| . . ...||.|||||..||.||||
ypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdvfdwlPlaalidekvlv

0045823 Metallo-dependent phosphatases 14-63 3.2e-15 48.9 In-house 135-184 (473) alignment
Range on Protein: 14-63
Range on HMM: 135-184/473.0
LGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
.|||||  .|..||| .|. .||. .. . | |....||||.||..|.|.
rGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilf

0049330 Metallo-dependent phosphatases 10-63 5.5e-15 48.6 In-house 118-171 (309) alignment
Range on Protein: 10-63
Range on HMM: 118-171/309.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVLV
  . .|||||  .|..||| .|.. ||. .. . |......||||.||..|.|.
vfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilc

subfamily_PPP7C_pd Subfamily PPP7C 6-63 1.4e-14 46.6 In-house 121-182 (383) alignment
Range on Protein: 6-63
Range on HMM: 121-182/383.0
VHVN-YLIFLGNHELITMNQMYGFEGEVKKKY---NGKMADLFTEVFNWLPLAHVIDNKVLV
|. .   .  ||||   .|  |||  ||..||   . |.  |. .|| ||||| .||.|.|.
vypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekili

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 12-62 3.1e-14 45.6 In-house 100-150 (287) alignment
Range on Protein: 12-62
Range on HMM: 100-150/287.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||.  .|..|||. |.|.|.....   | .||. |||   .....|
llrGnhevkkinklyGfkeelkrkrqerlykqfndvfselplcarvskril

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 8-62 4.9e-14 45.1 In-house 110-165 (298) alignment
Range on Protein: 8-62
Range on HMM: 110-165/298.0
VNYLIFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||  ..|..|||  |.|..| . ..   | .|||.|||. .| ...|
nnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggril

0053225 Metallo-dependent phosphatases 10-62 2e-13 43.7 In-house 110-163 (293) alignment
Range on Protein: 10-62
Range on HMM: 110-163/293.0
YLIFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
  . .|||||  .|..||| .|.. || . .. | .......||||..|..|.|
vvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkil

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 12-62 3.6e-13 42.2 In-house 106-156 (290) alignment
Range on Protein: 12-62
Range on HMM: 106-156/290.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||   .|..|||  |. .| ....   . .||. |.|   ...|.|
llrgnhevrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkil

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 8-62 4.4e-13 42.2 In-house 109-164 (297) alignment
Range on Protein: 8-62
Range on HMM: 109-164/297.0
VNYLIFLGNHELITMNQMYGFEGEVKKKYNG-KMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||   .|..|||  |..|.|.  .|   | .|||||||. .| .|.|
gnlfllrgnhecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkil

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 9-62 7e-13 41.3 In-house 93-146 (280) alignment
Range on Protein: 9-62
Range on HMM: 93-146/280.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
|.||. |||| |..|. |||  |||..|. .. . | |... |||. ..  ..|
nflilrgnhevisinrkygfkdevkrryslalynefqelldslplvalvsgril

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 12-62 2.6e-12 39.5 In-house 136-186 (317) alignment
Range on Protein: 12-62
Range on HMM: 136-186/317.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|. |||  ||||.|. .. . |  .|| |||. |...|.|
llrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkil

subfamily_PPP2C_pd Subfamily PPP2C 12-62 9.2e-11 34.5 In-house 107-158 (290) alignment
Range on Protein: 12-62
Range on HMM: 107-158/290.0
IFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
|. ||||   . |.||| .|. .|| | ..  .||..|..|||. ..|....
ilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqif

subfamily_PPP3C_pd Subfamily PPP3C 10-62 1.1e-10 33.9 In-house 129-181 (452) alignment
Range on Protein: 10-62
Range on HMM: 129-181/452.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
. .. ||||   . . . |. |.|.||. .. | ..| |. |||| ..... |
lfllrGnhecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqfl

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 9-62 1.2e-10 34.1 In-house 111-165 (299) alignment
Range on Protein: 9-62
Range on HMM: 111-165/299.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNG-KMADLFTEVFNWLPLAHVIDNKVL
.. .. ||||  ..|..|||  |..|.|.  ..  .| . |...||. .| ...|
rffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsril

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 1-62 1.6e-10 33.9 In-house 92-154 (284) alignment
Range on Protein: 1-62
Range on HMM: 92-154/284.0
FTFCVVHVNYLIF-LGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
|.. ... . ...  ||||   .|. |||  | ||.|  .. . |   || .||. |...|..
fayklllpdkvfllrgnhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkii

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 9-62 1.9e-10 33.4 In-house 95-148 (281) alignment
Range on Protein: 9-62
Range on HMM: 95-148/281.0
NYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
. ... ||||. ..|..|||  | . ||  ..  || . || ||..  |...||
rivllrgnheiasvnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvl

subfamily_PPG1_pd Subfamily PPG1 12-61 2.4e-10 33.1 In-house 104-155 (300) alignment
Range on Protein: 12-61
Range on HMM: 104-155/300.0
IFLGNHELITMNQMYGFEGEVKKKY--NGKMADLFTEVFNWLPLAHVIDNKV
.. ||||   . |.||| .|. .||  | .. . .||.|..| || .||...
llrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideei

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 2-62 2.6e-10 33.0 In-house 96-161 (302) alignment
Range on Protein: 2-62
Range on HMM: 96-161/302.0
TFCVV-HVNYLIFLGNHELITMNQMYGFEGEVKKKY----NGKMADLFTEVFNWLPLAHVIDNKVL
.. |.   ||... ||||  ..|  |||..|.....      .. . | ||| ..||| .. .|.|
alkvlyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekil

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 2-62 2.9e-10 32.8 In-house 97-162 (302) alignment
Range on Protein: 2-62
Range on HMM: 97-162/302.0
TFCVV-HVNYLIFLGNHELITMNQMYGFEGEVKKKY----NGKMADLFTEVFNWLPLAHVIDNKVL
.. |.   ||... ||||  ..|  |||..|.....      .. . | ||| ..||| .. .|.|
alkvlyptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekil

subfamily_PPZ_pd Subfamily PPZ 8-62 2.9e-10 33.1 In-house 111-165 (300) alignment
Range on Protein: 8-62
Range on HMM: 111-165/300.0
VNYLIFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
 |.... ||||   . ..|||  |.|.. | |.   | . || |||| ..  |..
enffllrgnhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkif

subfamily_PPP4C_pd Subfamily PPP4C 12-62 2.9e-10 32.8 In-house 106-157 (288) alignment
Range on Protein: 12-62
Range on HMM: 106-157/288.0
IFLGNHELITMNQMYGFEGEVKKKYN-GKMADLFTEVFNWLPLAHVIDNKVL
.  ||||   . |.|||  |. .||   ..  . ||||..|.|| .||.|..
lirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkif

subfamily_PPP6C_pd Subfamily PPP6C 12-62 3.1e-10 32.6 In-house 105-156 (290) alignment
Range on Protein: 12-62
Range on HMM: 105-156/290.0
IFLGNHELITMNQMYGFEGEVKKKY-NGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||   . |.|||  | ..|| |..    .|.||. |..| .||..||
llrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvl

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 12-62 1.4e-09 30.5 In-house 155-205 (339) alignment
Range on Protein: 12-62
Range on HMM: 155-205/339.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|  |||  ||. .|. .. . | ..|| .|.. ||.| ..
llrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntim

Metallophos Calcineurin-like phosphoesterase 8-63 9.1e-09 28.9 Pfam-A 66-155 (200) alignment
Range on Protein: 8-63
Range on HMM: 66-155/200.0
VNYLIFLGNHELITMNQMYGFEGEVK----------------------------------KKYNGKMADLFTEVFNWLPLAHVIDNKVLV
...   .||||   .|. |||  |.                                   ...... .. . |.|..|||.. .|.|.|.
ipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkill

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 1-62 1.6e-08 27.3 In-house 81-144 (284) alignment
Range on Protein: 1-62
Range on HMM: 81-144/284.0
FTFCVVHVNYL-IFLGNHELITMNQMYGFEGEVKKKYNGK-MADLFTEVFNWLPLAHVIDNKVL
|.. |.  |.. .. ||||   .|..|||  |....||   .   |  ||  .||. .. ...|
faykvifpnhffmlrgnhecslinkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqril

subfamily_PPPLV_pd Subfamily PPPLV 10-62 2.6e-08 26.5 In-house 89-144 (290) alignment
Range on Protein: 10-62
Range on HMM: 89-144/290.0
YLIFLGNHELITMNQMYGFEGEVKKKYNGKMAD---LFTEVFNWLPLAHVIDNKVL
.|.. ||||| .. . . . || . |.  .. .    |..||..|||| |||.||.
vlllrgnhelesvqesieykgegsfkfgdsleevweafnnvfdalplaavidrkvf

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 12-62 1e-07 24.7 In-house 96-146 (280) alignment
Range on Protein: 12-62
Range on HMM: 96-146/280.0
IFLGNHELITMNQMYGFEGEVKKKYNGKMADLFTEVFNWLPLAHVIDNKVL
.. ||||  ..|..|||  |.. ||   .   |  .|| .|.. .| ..||
llrgnhetpsvnkiygfyvecqykygvglwwdfqscfnrmpmsgliskrvl

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 12-62 1.1e-07 24.8 In-house 70-125 (263) alignment
Range on Protein: 12-62
Range on HMM: 70-125/263.0
IFLGNHELITMNQMYGFEGEVKKKYNGK-----MADLFTEVFNWLPLAHVIDNKVL
.. ||||| ..|. |||  |.||... .     . . | .||...||. .. ...|
llrgnhelkainknygfhaelkkrfqreevyesvynhfnqvfsymplcaivskril

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 5-62 2.7e-06 19.8 In-house 102-163 (307) alignment
Range on Protein: 5-62
Range on HMM: 102-163/307.0
VVH-VNYLIFLGNHELITMNQMYGFEGEVK---KKYNGKMADLFTEVFNWLPLAHVIDNKVL
...  | ... ||||.  .|. |||  |.     |   ..  ||  .|| ||.. .|  |.|
icypenivllrgnheiarvnkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkil