Gene CG9801-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP199_AA protein Get Run
AqueP199_AA_109-310 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 114-310 2.4e-110 356.7 In-house 1-198 (199) alignment 
Range on Protein: 114-310
Range on HMM: 1-198/199.0
HGDPIADAFFLTARPNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEKLFGSPSKPTNTQDIFHHILLSFDEAQKRIIANEGTTTTLTVAMICECLPN
.|.|.||.|...||.|..||..|||.|||.|||.|||.|..|........||....||||........|.|.|||.|.|...|||.|||..|..||..||
vGepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpn

HHISSRWVLCSVSVGDSPCFLYQPDYGSVHEVTAAWHDGKG-RDPRDSGGCLGTNVGNDPDLSNLICCLLPVREGDFIFITSDGISDNFDPVILKEAS
...||||.|...||||||.|.|.||..||||.|.|.||..| |..|.|||.||...|.||||.||....|||.|||....|.|||||||.||.|||||
srsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvvlkeas
subfamily_CG9081_pd Subfamily CG9081 114-308 8.6e-102 329.3 In-house 1-195 (195) alignment 
Range on Protein: 114-308
Range on HMM: 1-195/195.0
HGDPIADAFFLTARPNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEKLFGSPSkPTNTQDIFHHILLSFDEAQKRIIANEGTTTTLTVAMICECLPN
.|.|.||.|...||.|..||.||||.|||.|.|.|||||. |.|..||.|||.... ..|..|.|...| |..||||.|..|.||.|||..|..||. .|
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsa.kpnsrdlfklllesleeaqksilensgtlttlsiavvcelkan

HHISSRWVLCSVSVGDSPCFLYQPDYGSVHEVTAAWHDGKG-RDPRDSGGCLGTNVGNDPDLSNLICCLLPVREGDFIFITSDGISDNFDPVILKE
..|||.|.|..|||||||.|.|.||..||.|||.|.|...| ||.|.|||.||...|.||||.||....|||.|||..|.||||.|||||||..||
kkissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvvvke
subfamily_CG9801_pd Subfamily CG9801 114-309 1.7e-51 165.0 In-house 2-219 (252) alignment 
Range on Protein: 114-309
Range on HMM: 2-219/252.0
HGDPIADAFFLTARPNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEKLFGSPskpTNTQDIFHHILLSFDEAQKRIIANEGT-----TTTLTVAMIC
.|||||| |... | |. |. ||||.||| .|. |||||  .....|...|.      |..|......| .. || |.|......     ||||..... 
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei...ttvqevgksllaaleeahksivegkselweaGtttLlggvll

ECLP--------------------NHHISSRWVLCSVSVGDSPCFLYQPDYGSVHEVTAAWHdGKGRDPRDSGGCLGTNV-GNDPDLSNLICCLLPVREG
|                       ... ||.|.....||||. .|||      | ..| . . .. .|.||.|| ||  | .. |||.|| . ...| |.
elekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr.snlsDarDagGrLGPyveqgkPdLrnLklfftlveee

DFIFITSDGISDNFDPVILKEA
| |...|||..||.||. |. .
DiillvsDGvhDnlDPqtlgkt
subfamily_tipA_pd Subfamily tipA 214-306 4.4e-18 55.1 In-house 147-239 (296) alignment 
Range on Protein: 214-306
Range on HMM: 147-239/296.0
HHISSRWVLCSVSVGDSPCFLYQPDYGSVHEVTAAWHdGKGRDPRDSGGCLGTNVGN-DPDLSNLICCLLPVREGDFIFITSDGISDNFDPVIL
.. ||.|.. ..||||   ||.  .   | ..|     .   |..|.|| ||  | .  ||| ||   .|.. | | |.. |||. ||.||  |
nkssskWgfvcasvGdckafllskkskevtditkgnr.snvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktl
subfamily_tipA_pd Subfamily tipA 109-202 4.1e-17 51.9 In-house 1-95 (296) alignment 
Range on Protein: 109-202
Range on HMM: 1-95/296.0
NSTSHHGDPIADAFFLTARPNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEKlfgsPSKPTNTQDIFHHILLSFDEAQKRIIAN-----EGTTTTL
|.| ..|||||| |. . . |  |. |||| ||| .|. ||..|  . |..|.||     |. .. .|. ...| .| .| |.|..      |  ||||
nttkregdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflsek....sseintvkdaGkfllsafeaahkkiveGksdiweaGtttl
0049733 PP2C-like 119-310 2.7e-13 43.1 In-house 19-201 (235) alignment 
Range on Protein: 119-310
Range on HMM: 19-201/235.0
ADAFFLtarpNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEklfgspSKPTNTQDIFHHILLSFDEAQKRIIA----NEGTTTTLTVAMICeclPNh
 ||...    .  ....|||.. .   ..|.. ..  ....| |        ............|  .||  .         |  ||..||...   .. 
eDavlv....glllfavaDGhgghaagevasellvetllellle......lllldleealrkaflaaneallelalaspelagmgtTavvalld...gg.

hissrwVLCSVSVGDSPCFLYQpdYGSVHEVTA-----------AWHDGKGRDPRDSGGCLGTNVGnDPDLSnLICCLLPVREGDFIFITSDGISDNFDP
       |. ..|||| ..|..   | .. .|             ...  |.     . .|   .| |..|.    . |....|||....|||..|....
......klyvanvGDsrayllr..dgklvqltedhspvnelerqriitaggavrvpgrlaltralG.dlllk.pdvtvlelepgdflllasDGlwdvlsd

VILKEAS
  . .  
eeivdll
0034914 PP2C-like 115-303 1.5e-10 33.7 In-house 32-246 (295) alignment 
Range on Protein: 115-303
Range on HMM: 32-246/295.0
GDPIADAFFLTA-----RPNSCIMGLADGINWGYKPRIAARSALLGVVNHLNEKLFGSPSKPTNTQDIFHHILLSFDEAQKRIIAN----EGTTTTLTVA
 ..  ||..         .. ...|..|| .  .  ..|.. ..  ....|.. |. ... ... ..... ..|. ||.  . . .     |  ||..||
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavva

MICEClpnhhissrwVLCSVSVGDSPCFLYqpDYGSVHEVTAAWH-------------DGKGRDPRDSGGCLGTNVGNDPDLS----------------N
.|..            |    |||| ..|.    | .. .|   .             .|  ...|  |.   |    | ||                  
lirgn..........klyvanvGDSravll..rngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePd

LICCLLPVREGDFIFITSDGISDNFDP
...  | . ..||. . |||..|....
vtvleltledddfllLasDGlwdvlsn
PP2C_SIG_SM00331 119-300 4.1e-10 32.6 In-house 18-163 (217) alignment 
Range on Protein: 119-300
Range on HMM: 18-163/217.0
ADAFFLTARPN-SCIMGLADGINWGYKPRIAARSALLGVVNHLNEKlfgspskpTNTQDIFHHILLSFDEAqkriIANEGTTTTLTVAMIceclpnHHIS
 | ..... .. . .. .|||.  |.    |.....  . ..|.|.        ..........   ..|       ..|  .||..|..      .  |
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg........eelsqalkrlnraiyee....keekgmfaTlllaly......dfss

SRwvLCSVSVGDSPCFLYQpDYGSVHEVTAawhdgkgrdprDSGGCLGTNVGNDPDLSNLICCLlpvreGDFIFITSDGISDN
..  |  ...|||...|.. | . |.....            .| .||. .  ..| ..|.        ||.... .||. ..
gk..lsyanaGdsrpyllr.dgklveilkd...........vegaplGlepevsvdirelelek.....gdllllytDGltea
PP2C_2 Protein phosphatase 2C 110-302 5.5e-09 28.6 Pfam-A 4-182 (212) alignment 
Range on Protein: 110-302
Range on HMM: 4-182/212.0
STSHHGDPIADAFF-LTARPNSCImGLADGINWGYKPRIAARSALLGVVNHLNEKLfGSPSKP---TNTQDIFHHILLS---FDEAQKRIIANEGTTTTL
|  . | |  ||..  .|.  ...   |||       ...|| |   ....| ..|  . |..   .  ..| ..|| |   ..||...    .   |||
shrrkgkpcqDalaireasdgwll.aVADGaGsakrSdkGarlaveaagealekll.eeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTl

TVAMICeclpnhhisSRWvLCSVSVGDSPCFLYQPDyGSVHEVTAawhdgkgrdpRDSGGCLG-TNVGNDPD-LSNLICCLLPVREGDFIFITSDGISDN
..|.|.         ... ......||. ......| |.|. ..           .|||.  . |.   ..|  ..|    |....|| .....||.||.
llavit.........pge.ivffqiGDgaivvrdrd.gevqllge..........pdsgeyanettfltsedaeeelrirrlklepgdalllmTDGvsds

FD
. 
lr
PP2C_2 Protein phosphatase 2C 110-302 5.5e-09 28.6 In-house 4-182 (212) alignment 
Range on Protein: 110-302
Range on HMM: 4-182/212.0
STSHHGDPIADAFF-LTARPNSCImGLADGINWGYKPRIAARSALLGVVNHLNEKLfGSPSKP---TNTQDIFHHILLS---FDEAQKRIIANEGTTTTL
|  . | |  ||..  .|.  ...   |||       ...|| |   ....| ..|  . |..   .  ..| ..|| |   ..||...    .   |||
shrrkgkpcqDalaireasdgwll.aVADGaGsakrSdkGarlaveaagealekll.eeeseqeeeallrqieneilasvklkqeaeaqqeelkdyatTl

TVAMICeclpnhhisSRWvLCSVSVGDSPCFLYQPDyGSVHEVTAawhdgkgrdpRDSGGCLG-TNVGNDPD-LSNLICCLLPVREGDFIFITSDGISDN
..|.|.         ... ......||. ......| |.|. ..           .|||.  . |.   ..|  ..|    |....|| .....||.||.
llavit.........pge.ivffqiGDgaivvrdrd.gevqllge..........pdsgeyanettfltsedaeeelrirrlklepgdalllmTDGvsds

FD
. 
lr