Gene CG9801-2 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP200_AA protein Get Run
AqueP200_AA_223-434 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 225-435 7.8e-113 364.9 In-house 2-197 (199) alignment 
Range on Protein: 225-435
Range on HMM: 2-197/199.0
GEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINATP-HSRTLTTLLLEAMENAHQCILEHSGTLTTLSIGIVCQLKPNk
||||||||||.|||||.|||||||||||||||||||||||.||||||||..|..|.| .|||||.||||....||..||||.||||||||..||.|||| 
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpn.

ktllttstpnssstlSRSSSNWGLFIASVGDSPIFVYSPTNKSITEATVACHPKDGIRTAAFSGGALGPAIGTQADMENLSLNYLPVAEGDIVFMTTDGI
               |||||.||||.|||||||.|||||..||..|||||||.|||||||..|||||||||||..|.|||||.||||||||||..|||||
...............srsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGi

SDNFYPQVIRPG
||||.|.|....
sdnfapvvlkea
subfamily_CG9081_pd Subfamily CG9081 224-433 3.5e-108 350.1 In-house 1-194 (195) alignment 
Range on Protein: 224-433
Range on HMM: 1-194/195.0
AGEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINATPHSRTLTTLLLEAMENAHQCILEHSGTLTTLSIGIVCQLKPNK
|||||||||||.|||||.|||.|||||||||.|||||.||..|.||..|...|..|.|.||.|..||||..|.|...|||.|||||||||..||.||.||
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilensgtlttlsiavvcelkank

KTllttstpnssstlsrsSSNWGLFIASVGDSPIFVYSPTNKSITEATVACHPKDGIRTAAFSGGALGPAIGTQADMENLSLNYLPVAEGDIVFMTTDGI
|.                ||.||||..||||||.|||||.|||..|.|||.|.|||||....|||||||||||..|.|||||.|||||||||||.|.||.
ki................ssqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGv

SDNFYPQVIR
||||.|.|..
sdnfdPvvvk
subfamily_CG9801_pd Subfamily CG9801 224-432 1.6e-53 171.7 In-house 2-216 (252) alignment 
Range on Protein: 224-432
Range on HMM: 2-216/252.0
AGEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINatPHSRTLTTLLLEAMENAHQCILEHSGTL-----TTLSIGIVCQ
.|.|.||.| |  |.|..|.|.|||.|||..|..|||.|....| |.|....|       .   . ||.|.|.||..|.|  ..|     ||| .|.. .
eGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei..ttvqevgksllaaleeahksivegkselweaGtttLlggvlle

LKPNKKTLLTTSTP----NSSSTLSRSSSNWGLFIASVGDSPIFVYSPTNKSITEATVACHpkDGIRTAAFSGGALGP-AIGTQADMENLSLNYLPVAEG
|. ...   ..|      .. |.  .|||.||.  |||||.  |.||  .| .|. | . .  . .. |  .||.||| . . . |..||.| ...| |.
lekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr..snlsDarDagGrLGPyveqgkPdLrnLklfftlveee

DIVFMTTDGISDNFYPQVI
||.... ||..||. ||..
DiillvsDGvhDnlDPqtl
subfamily_tipA_pd Subfamily tipA 223-433 2.9e-33 104.9 In-house 5-240 (296) alignment 
Range on Protein: 223-433
Range on HMM: 5-240/296.0
VAGEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINATphsRTLTTLLLEAMENAHQCILEH------SGTlTTLSIGIV
 .|.|.|| |.|  ..|  |.|.||| ||||.|. ||. |... . ..|.. ..||.    .    .||.|.| ||. |.|       .|| |||  |..
regdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflseksseintv...kdaGkfllsafeaahkkiveGksdiweaGt.ttllGGvl

CQL-----KPNKK----------TLLTTS---------TPNSSSTLSRSSSNWGLFIASVGDSPIFVYSPTNKSITEATVAChpKDGIRTAAFSGGALGP
 .|     ||. .            ....           |. |   .|||.||.  |||||   | .| ..| .|. |     .  .  |  .|| |||
leleqseskpesssqkrksevnkeviganfanltgsgngnnagsdinkssskWgfvcasvGdckafllskkskevtditkgn..rsnvddakdpGGrlGP

AIGT-QADMENLSLNYLPVAEGDIVFMTTDGISDNFYPQVIR
 .   . |. ||.| .|.. | ||... .||. ||. |. . 
yveqGkPdlrnlklffllceeediillvsdGvhdnldPktlg
0049733 PP2C-like 230-433 1.2e-14 47.4 In-house 20-198 (235) alignment 
Range on Protein: 230-433
Range on HMM: 20-198/235.0
DVFAVlareNNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDninkinatPHSRTLTTLLLEAMENAHQCILEHSGT-------LTTLSIGIVCqlkPN
| ..|    . ...|.|||.. .   ..|....|.| .... .        ... .|...| .|.. |....||.. .        ||... ...   ..
Davlv....glllfavaDGhgghaagevasellvetllellle........lllldleealrkaflaaneallelalaspelagmgtTavvalld...gg

KktllttstpnssstlsrsssnwgLFIASVGDSPIFVYSptNKSITEATVACHP----------KDGIRTAAFSGGALGPAIGtQADMEnLSLNYLPVAE
|                       |..|.|||| .....  .. ..  |.  .|          . | .   . . ||  |.| . ...   . .|.. .
k.......................lyvanvGDsrayllr..dgklvqltedhspvnelerqriitaggavrvpgrlaltralG.dlllk.pdvtvlelep

GDIVFMTTDGISDNFYPQVIR
||......||..|.. .. | 
gdflllasDGlwdvlsdeeiv
PP2C_2 Protein phosphatase 2C 224-429 7.5e-13 41.2 Pfam-A 8-183 (212) alignment 
Range on Protein: 224-429
Range on HMM: 8-183/212.0
AGEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINATPhsrtlTTLLLEAMENAHQCI-LehsgtlttlsigivcQLKPN
.|.|  | .|.   ..  ..|.|||.   |  . .||.||..|. ........ ...      .. ||...||. . .                 . . .
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe.....eeallrqieneilasvk...............lkqea

KKTLLTTSTPNSSSTLSRSSSNWgLFIASVGDSPIFVYSptnkSITEATVACHPKDgirtAAFSGGaLGPAIGTQAdMENLSLNYLPVAEGDIVFMTTDG
...  . .   .  .|   .... ......||. |.|..    .  |......|.       ...  .  .   .|  |.| .. |.. .|| ....|||
eaqqeelkdyatTlllavitpge.ivffqiGDgaivvrd....rdgevqllgepds....geyane.ttfltseda.eeelrirrlklepgdalllmTDG

ISDNFYP
.||.. .
vsdslrk
PP2C_2 Protein phosphatase 2C 224-429 7.5e-13 41.2 In-house 8-183 (212) alignment 
Range on Protein: 224-429
Range on HMM: 8-183/212.0
AGEPVADVFAVLARENNTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNINKINATPhsrtlTTLLLEAMENAHQCI-LehsgtlttlsigivcQLKPN
.|.|  | .|.   ..  ..|.|||.   |  . .||.||..|. ........ ...      .. ||...||. . .                 . . .
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe.....eeallrqieneilasvk...............lkqea

KKTLLTTSTPNSSSTLSRSSSNWgLFIASVGDSPIFVYSptnkSITEATVACHPKDgirtAAFSGGaLGPAIGTQAdMENLSLNYLPVAEGDIVFMTTDG
...  . .   .  .|   .... ......||. |.|..    .  |......|.       ...  .  .   .|  |.| .. |.. .|| ....|||
eaqqeelkdyatTlllavitpge.ivffqiGDgaivvrd....rdgevqllgepds....geyane.ttfltseda.eeelrirrlklepgdalllmTDG

ISDNFYP
.||.. .
vsdslrk
PP2C_SIG_SM00331 230-427 1.9e-10 33.7 In-house 19-164 (217) alignment 
Range on Protein: 230-427
Range on HMM: 19-164/217.0
DVFAVLAREN-NTIMAIADGVNWGKKPRLAARCAVQTAIAYISDNinkinatphsrtltTLLLEAMENAHQ----Cilehsgtlttlsigivcqlkpnkk
|.. |.. ..  .....|||.  |.   .|.. ...    ..|..              . | .|.... .                             
DyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg..............eelsqalkrlnraiyee........................

tlltTSTPNSSSTLSRSS---SNWGLFIASVGDSPIFVYSptNKSITEATVAchpkdgirtaafsggALGPAIGTQADMEnLSLNYLPVAEGDIVFMTTD
    . . ..  || .     |.  | .|..|||.....   ..  .| . .                .|...|.. . . .    | . .||.... ||
....keekgmfaTlllalydfssgklsyanaGdsrpyllr..dgklveilkd...............vegaplGlepevs.vdirelelekgdllllytD

GISDNF
|. .. 
Gltear
0034914 PP2C-like 229-434 8.7e-09 27.9 In-house 36-251 (295) alignment 
Range on Protein: 229-434
Range on HMM: 36-251/295.0
ADVFAVLA-----RENNTIMAIADGVNwgkkPRLAARCAVQTAIAYISDNINKI--NATPHSRTLTTLLLEAMENAHQCILEHSGTL-------TTLSIG
 | . |.       |. ......||..       ||. | .... .......|.  ..|. . .. . | .|. .|.. .||..          ||... 
eDavlvvlnllslledlllfgvfDGhg....GhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavva

IVCQLkpnkktllttstpnssstlsrsssnwGLFIASVGDSPIFVYspTNKSITEATVACHPKDG-----IRTA--------AFSGGALGPAIGTQADME
....                            |..| |||| ....  .|. ..  ||  .| .      |..|         . . |.  |.|    . 
lirgn..........................klyvanvGDSravll..rngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlkl

---------------NLSLNYLPVAEGDIVFMTTDGISDNFYPQVIRP
                ..   | . ..|.. . .||..|.. .. |  
llslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivd
PPM_PTC7_SpoIIE 341-432 6.6e-06 19.1 In-house 101-177 (230) alignment 
Range on Protein: 341-432
Range on HMM: 101-177/230.0
SSSNWGLFIASVGDSPIFVYSPtNKSiteatvachpkdgirTAAFSgGALGPA-IGTQADMENLSlNYLPVAEGDIVFMTTDGISDNF--YPQVI
 .|.. | .|..||||...... ..                ..    .| |.. .|   . .. .   .. |.||. .. |||. ..    .. .
dpstgklyvanaGdsppllvrd.dgg...............ereri.vagglpslGilpgrvfgv.lavslapGdllllytDGvveaepdtsdge