Gene CG9801-3 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily CG9801
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP201_AA protein Get Run
AqueP201_AA_102-303 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 108-303 1.9e-109 353.8 In-house 1-199 (199) alignment 
Range on Protein: 108-303
Range on HMM: 1-199/199.0
VGGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSVKKPTSATLNKLLHESMDIAHKSILSHGGTLTTLSIAVACEL---
||.||||||.||.||||||||||||..||||.||||||||.||||.|.|||.|||.|...|.||.|||.||.|.||||||.|.||||||||||.|||   
vGepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksileheGtlttlsiavvcelkpn

SAPSNQWGLFVASVGDSPVFVYCPHTYQLHEATVDCHSKDGNRVVQLSGGALGPAIGTLPDLDNFSMSYSPVYPGDIVLLMTDGVYDNFAPGVVQAVHD
|..|..||||||||||||||||.|.|...|||||.||.|||.|...|||||||||||| |||.|.|.||.||..||||||.|||..|||||.|......
srsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGtdpdlenlslsylpvaeGdivllttdGisdnfapvvlkeasa
subfamily_CG9081_pd Subfamily CG9081 108-299 1.4e-102 331.9 In-house 1-194 (195) alignment 
Range on Protein: 108-299
Range on HMM: 1-194/195.0
VGGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSVkKPTSATLNKLLHESMDIAHKSILSHGGTLTTLSIAVACELSAP
.|.||||||.||.||||||||.|||..||||||||||.||.||.|...|.|.|||. ||.|..|.|||.||...|.||||...||||||||||.|||.|.
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsa.kpnsrdlfklllesleeaqksilensgtlttlsiavvcelkan

---SNQWGLFVASVGDSPVFVYCPHTYQLHEATVDCHSKDGNRVVQLSGGALGPAIGTLPDLDNFSMSYSPVYPGDIVLLMTDGVYDNFAPGVVQ
   |.||||||.||||||||||.|......|.||..|||||.|.|.|||||||||||| |||.|.|.||.||..||||.|..|||.|||.|.||.
kkissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGtdpdlenlslsylpvaeGdivfltsdGvsdnfdPvvvk
subfamily_CG9801_pd Subfamily CG9801 109-310 2.2e-41 132.0 In-house 3-228 (252) alignment 
Range on Protein: 109-310
Range on HMM: 3-228/252.0
GGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSvkkPTSATLNKLLHESMDIAHKSILSHGGTL-----TTLSIAVACE
| |.||.|.||||.|..|.|.|||  ||.....|||.|....| .....|.| .    |     | | ...  |||||.  ...|     ||| ..|  |
GdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskei...ttvqevgksllaaleeahksivegkselweaGtttLlggvlle

LSA-----------------------PSNQWGLFVASVGDSPVFVYCPHTYQLHEATVDCHskDGNRVVQLSGGALGP-AIGTLPDLDNFSMSYSPVYPG
|.                        .|..||. .|||||.  |.|  ..... . |   .  .  .  . .||.||| . .  ||| | .... .|. .
lekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnr..snlsDarDagGrLGPyveqgkPdLrnLklfftlveee

DIVLLMTDGVYDNFAPGVVQAVHDERALDCD
||.||. ||| ||. | ... . ..  |. .
DiillvsDGvhDnlDPqtlgktprdlnlnae
0049733 PP2C-like 114-302 1.6e-16 53.6 In-house 20-201 (235) alignment 
Range on Protein: 114-302
Range on HMM: 20-201/235.0
DVFGVvvreNNAIMAIADGSGWGKKARLAARCAVNGAIAHITDnlhklsvkkPTSATLNKLLHESMDIAHKSILSHGGT-------LTTLSIAVACelsa
| . |    . ...|.||| | .  ...|....|.  .... .         ... .| ..|....  |.. .|... .        ||...|. .    
Davlv....glllfavaDGhgghaagevasellvetllellle.........lllldleealrkaflaaneallelalaspelagmgtTavvalld....

psnQWGLFVASVGDSPVFVYCphTYQLHEATVDCHS----------KDGNRVVQLSGGALGPAIGtLPDLDnFSMSYSPVYPGDIVLLMTDGVYDNFAPG
   .  |.||.|||| ....     .|.  |.| .           . |..|. . . ||  |.|  ..|. . ... .. |||..||..||..|.. . 
...ggklyvanvGDsrayllr..dgklvqltedhspvnelerqriitaggavrvpgrlaltralG.dlllk.pdvtvlelepgdflllasDGlwdvlsde

VVQAVH
 .... 
eivdll
subfamily_tipA_pd Subfamily tipA 202-301 1.2e-15 47.0 In-house 144-242 (296) alignment 
Range on Protein: 202-301
Range on HMM: 144-242/296.0
CELSAPSNQWGLFVASVGDSPVFVYCPHTYQLHEATVDCHSKDgnRVVQLSGGALGPAIGT-LPDLDNFSMSYSPVYPGDIVLLMTDGVYDNFAPGVVQA
..  ..| .||.  |||||   | .  .. .. . | .  |       . .|| ||| .    ||| |... . .... ||.||..|||.||. |  .  
sdinkssskWgfvcasvGdckafllskkskevtditkgnrsnv..ddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktlgk

V
 
t
PP2C_SIG_SM00331 107-292 3e-15 49.4 In-house 15-163 (217) alignment 
Range on Protein: 107-292
Range on HMM: 15-163/217.0
QVGgpvADVFGVVVREN-NAIMAIADGSGWGKKARLAARCAVNGAIAHITDNlhklsvkkptsATLNKLLHESMDIAHKSiLSHGGTLTTLSIAVAcels
||.    |...||  ..   ....|||.| |. | .|.. ...    .....            .| ..|.. .. ...     .|  .|| .|.     
qvs...GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg...........eelsqalkrlnraiyee.keekgmfaTlllaly....

aPSNQWGLFVASVGDSPVFVYCphTYQLHEATVDchskdgnrvvqlsggALGPAIGTLPDLDnFSMSYSPVYPGDIVLLMTDGVYDN
 . ..  | .|..|||.....     .| | . |                .|...|. |... . ..   . .||..||.|||. ..
.dfssgklsyanaGdsrpyllr..dgklveilkd...............vegaplGlepevs.vdirelelekgdllllytDGltea
PP2C_2 Protein phosphatase 2C 107-295 4.3e-15 48.6 Pfam-A 7-183 (212) alignment 
Range on Protein: 107-295
Range on HMM: 7-183/212.0
QVGGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSVKKpTSATLNKLLHESM------DIAHKSILSHGGTLTTLSIAV
. | |  | ... . ..  ..|.||| |  | .. .||.||. |. .....|.. | .. ..|.|.....|        . |...  .     |||..||
rkgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe.eeallrqieneilasvklkqeaeaqqeelkdyatTlllav

ACelsaPsnqWGLFVASVGDSPVFVYCpHTYQLHEATVDCHSKDGNRVVQLSGGALGPAIgtlpdldnfSMSYSPVYPGDIVLLMTDGVYDNFAP
..    |   ........||. ..|.  .. ... .. . . .  | .. |.  . ..            ..  .. ||| .||||||| |....
it....p...geivffqiGDgaivvrd.rdgevqllgepdsgeyanettfltsedaeeel.........rirrlklepgdalllmTDGvsdslrk
PP2C_2 Protein phosphatase 2C 107-295 4.3e-15 48.6 In-house 7-183 (212) alignment 
Range on Protein: 107-295
Range on HMM: 7-183/212.0
QVGGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSVKKpTSATLNKLLHESM------DIAHKSILSHGGTLTTLSIAV
. | |  | ... . ..  ..|.||| |  | .. .||.||. |. .....|.. | .. ..|.|.....|        . |...  .     |||..||
rkgkpcqDalaireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe.eeallrqieneilasvklkqeaeaqqeelkdyatTlllav

ACelsaPsnqWGLFVASVGDSPVFVYCpHTYQLHEATVDCHSKDGNRVVQLSGGALGPAIgtlpdldnfSMSYSPVYPGDIVLLMTDGVYDNFAP
..    |   ........||. ..|.  .. ... .. . . .  | .. |.  . ..            ..  .. ||| .||||||| |....
it....p...geivffqiGDgaivvrd.rdgevqllgepdsgeyanettfltsedaeeel.........rirrlklepgdalllmTDGvsdslrk
subfamily_tipA_pd Subfamily tipA 106-188 2.4e-13 39.6 In-house 4-82 (296) alignment 
Range on Protein: 106-188
Range on HMM: 4-82/296.0
RQVGGPVADVFGVVVRENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHKLSvkkpTSATLNKLLHESMDIAHKSILS
.. | |.|| | |.|..| .|.|.|||  |||. . ||. |... . ..... ....    |     |.| ...  |||.|. 
kregdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflsekssein....tvkdaGkfllsafeaahkkive
0034914 PP2C-like 111-303 4.4e-12 38.7 In-house 34-254 (295) alignment 
Range on Protein: 111-303
Range on HMM: 34-254/295.0
PVADVFGVVV-----RENNAIMAIADGSGWGKKARLAARCAVNGAIAHITDNlhkLSVKKPTSATLNKLLHESMDIAHKSILSHGGTLTTLSIAVACELS
.  | . ||.      |. ......|| |  . |..|.. .|.  . ..      |    ... .. . |....  |.. .|...     |.   .. . 
sneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl...lllltlsledieealrkaflaadeellelallrpelagsGtTavv

APSNQWGLFVASVGDSPVFVYcpHTYQLHEATVDcHSKDGNRVVQ------------------LSGGAL--------------GPAIGTLPDLDNFSMSy
|   .  |.|| |||| ....  .  .|.  ||| |. . . ...                      ||              .|..   ||.. .... 
alirgnklyvanvGDSravll..rngelvqltvd.hkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdvtvlelt.

spVYPGDIVLLMTDGVYDNFAPGVVQAVHD
  . ..|..||..||..|.. .  . ..  
..ledddfllLasDGlwdvlsneeivdivr
SpoIIE Stage II sporulation protein E (SpoIIE) 124-295 1.2e-09 30.3 Pfam-A 4-140 (193) alignment 
Range on Protein: 124-295
Range on HMM: 4-140/193.0
NAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHklsvkkptsatlnklLHESMDIAHKS-------IlshgGTLTTLSIAVacelsAPSNQWGLFVA
.  ....|..| | .| |... ...   . .|..|                ..| .. ...                .|. .|.        ... | .|
rlalvvgDvvGhGleAalimgllrsalrelatagle...............paevlerlnealarnleee....erfatavlae.....ydpstgkleya

SVGDSPVFVYCPHTyqlheatvdchskdGNRVVQLSGGALgpaIGTLPDlDNFSMSYSPVYPGDIVLLMTDGVYDNFAP
..|..|.... |..              | ...  | |..   .| ||.  ..     .. |||..||.||||... .|
naGhpppllvrpdg..............gtkfllvstglp...lGilpe.adyeeaelqlepgdllllyTDGvtEardp
SpoIIE Stage II sporulation protein E (SpoIIE) 124-295 1.2e-09 30.3 In-house 4-140 (193) alignment 
Range on Protein: 124-295
Range on HMM: 4-140/193.0
NAIMAIADGSGWGKKARLAARCAVNGAIAHITDNLHklsvkkptsatlnklLHESMDIAHKS-------IlshgGTLTTLSIAVacelsAPSNQWGLFVA
.  ....|..| | .| |... ...   . .|..|                ..| .. ...                .|. .|.        ... | .|
rlalvvgDvvGhGleAalimgllrsalrelatagle...............paevlerlnealarnleee....erfatavlae.....ydpstgkleya

SVGDSPVFVYCPHTyqlheatvdchskdGNRVVQLSGGALgpaIGTLPDlDNFSMSYSPVYPGDIVLLMTDGVYDNFAP
..|..|.... |..              | ...  | |..   .| ||.  ..     .. |||..||.||||... .|
naGhpppllvrpdg..............gtkfllvstglp...lGilpe.adyeeaelqlepgdllllyTDGvtEardp
PPM_PTC7_SpoIIE 126-293 2.4e-08 27.1 In-house 34-170 (230) alignment 
Range on Protein: 126-293
Range on HMM: 34-170/230.0
IMAIADGSGWGKKArlaarcavNGAIAHITDNLHKLSvKKPTSaTLNKLLHESMDIAH-----KsilsHGGTLTTLSIAVacelsAPSNQWGLFVASVGD
  ...|..| |  |          | ... . |..|. .. .. .....|... . ..     .    ..   .|...|.       .... | ||..||
alvvgdvdGhGgra........alamgllrtalrela.fagle.kpeeilrrlnlalaadlede....psssgaTavval.....idpstgklyvanaGd

SPVFVYCPhTYQlheatvdchskdgnrVVQLSgGALGPA-IGTLPDLDNFSmSYSPVYPGDIVLLMTDGVYDNF
||.... . . .               .. .  .| |.. .| ||. .. .    .  |||. || |||| .. 
sppllvrd.dgg...............ereri.vagglpslGilpgrvfgv.lavslapGdllllytDGvveae
subfamily_PPTC7_pd Subfamily PPTC7 123-299 2.5e-06 20.1 In-house 22-187 (252) alignment 
Range on Protein: 123-299
Range on HMM: 22-187/252.0
NNAIMAIADGS-GWGKKARLAARCAVNgaIAHITDNLHKLSVKKPTSAtlnkllHESMDIAHKSILSHGGTLTTLSiaVACELSAPSNQWGLFVASVGDS
.. .. .|||  || ..   ... . .  . . ...| | | .....        | .. |....| .. ..   |   || .   ...  | .| .|||
sadvlgvADGVggWrsvGiDpsefsre..LmkaceklskeskaeelkP......velleaayqelleekvpvlGss..TacivvldksdkklesanlGDS

PVFVYCPHtYQLHEATVDCHskDGNRVVQLSGGALGPAIGTLPDLDNFSMSY-SPVYPGDIVLLMTDGVYDNFAPGVVQ
 . |   .   .. ...  |  . |   |||  . |    .. |  . . |.  .| .|||..| |||..|| ..  . 
gflvvRkg.kvvfrskeqqh..kfntPyQLsiapegregkvildkpeaadsksfavkkgDiivlatDGlfDNlledeil