Gene PDP in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PDPc
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP205_AA protein Get Run
AqueP205_AA_88-446 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PDP_pd Subfamily PDP 85-446 4.6e-124 407.5 In-house 1-397 (398) alignment 
Range on Protein: 85-446
Range on HMM: 1-397/398.0
DINYLPSNSPNEDRYSFGGLPESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVSGSLNIHRDGDTLLD------------AGGTESLQLPDN
| | |.||.|.|||.|.. | ||.. ||.|.|||....||| ....|||.|...|..  |.. .......|..||.            .  ...|.| ..
dsnqLasNePiEDrrseakllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslsel

SD-----------KVPSLLRKSFLDLDKNISDGGLEAVelvkKGHSIRSnegifaKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSG-WEPV
|.           || . |.|.||.|||.||.  |...    |..|.|.      .|..||||||||.|.|......||.|||||||||.....| || |
skylqelleaevekvkealkkaFlklDkdistealkkl....kekslre......allvalsGacallaliegtelhvAntGDcravlgvqeeegsweav

ALSKDQNVHNEEEVNRVKSAHPGEED-TVIRESRLLGGLMPFRAFGDTEYKWPEEsLSHVHFVL--------GDYKTPPYLTAEPVVTSYP-STGGQFLI
.|||||...|||||.|.|..|||||. ||||..|||| |.|.|||||..|||.|| |.....           ||||||||||||.|||.. ..  .||.
kLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwsee.lqkkvlekaylkvlepkdyktPPYltaePevtshklrendkFLv

LGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSSKTFGLWSS------KEKTCCE--ESVNSATELLWESLGGS----DRSVKQLLEIPAGMSRMYRDDI
|.|||||. .........||.|..|. .|.........|...      ||.....  |. |.||.|....|||.    ...|..||.||....|||||||
latDGLwdllsneevvslVgehlakkkekepvkveeakltlkqvveelkerkrklkredknaAthLirhalggneagdkekvsallsiPeelaRmyRDDi

TIIVIHFK
|..|..|.
tvtVvffn
PP2Cc_SM00332 90-443 2.7e-55 180.7 In-house 19-274 (274) alignment 
Range on Protein: 90-443
Range on HMM: 19-274/274.0
PSNSPNEDRYSFGGL--PESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVSgslnihrdgdtlldaggteslqlpdnSDKVPSLLRKSFLDL
......||..       .|.....|.| |||    .|.|....| ... ..| .    .                          .|.|  .|.|.||..
gwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel..........................eddveealkkaflst

DKNISDGGLE----AvelvkkghsirsnegifaklaqALSGACALFAMINPQTIYVASTGDCRAVLGKKAGsgwePVALSKDQNVHNEEEVNRVKSAHPg
|..| .                               ||||..|. |... ...|||..||.||||...       |.||.|.....|.|..|.|.|.. 
deeileeeqskelen......................alsGstavvallkkedlyvanvGDSravlcrngk....avqlsvdhkpedederkRikkagg.

eedtVIRESRLLGGLMPFRAFGDTEYKWPEeslshvhfvlgdYKTPPYLTAEPVVTSYP-STGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEgnkdkt
    |..  |. |||.  ||||| ..|...            ....||.|||| |.     . ..|||| .||||. ...|...|.| .. .|.      
....vvekgrvngglavsrafGdhflkknk............klkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqevvdivrkllakg......

ssktfglwsskektcCEESVNSATELLWESLGGSdrsvkqlleipagmsRMYRDDITIIVI
                ....  | |||.| .  .               ....|.||..|.
...............ktndpqeaaelldeeairr...............ggseDniTvvvv
0034914 PP2C-like 89-446 2e-46 151.2 In-house 29-291 (295) alignment 
Range on Protein: 89-446
Range on HMM: 29-291/295.0
LPSNSPNEDRYSFGG---LPESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVSGSLnihrdgdtlldaggteslqlpdnSDKVPSLLRKSFL
   ...|||....       ... .||.| ||| . ..||.....|.... . |..  . . .                        .. . . |||.||
qGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltls.......................ledieealrkafl

DLDKNISDGGLEAvelvkkghsirsnegifakLAQALSGACALFAMINPQTIYVASTGDCRAVLGkkagSGWEPVALSKDQNVHNEEEVNRVKSAHPgee
 .|. . . .|.                       | ||..|. |.| ....||| .||.||||     ...|.| |..|... ||.|. |..||..   
aadeellelallr...................pelagsGtTavvalirgnklyvanvGDSravll....rngelvqltvdhkpvnelererilsagg...

dtVIRESRLLGGLMPFRAFGDTEYKWPeeslshvhfvLGDYKTPPYLTAEPVVTSYPS--TGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNkdkts
  ... .|..|.|.  ||.|| ..|..          | .. ..|...||| ||...     ..||.|..||||. . ...|.|.| ... |  .     
..avshgrvngvlavtRalGdfdlkll..........lslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrsllakgld.....

sktfglwsskektcceeSVNSATELLWESLGgsdrsvkqlleipagmsRMYRDDITIIVIHFK
                   . |.||. ..|                  |..||.||..|....
.................leeaaeeLvdlAla.................rgsrDNiTvvvvrln
PP2C Protein phosphatase 2C 105-385 4.6e-37 121.0 Pfam-A 30-241 (255) alignment 
Range on Protein: 105-385
Range on HMM: 30-241/255.0
PESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVsgslnihrdgdtlldaggteslqlpdnsdKVPSLLRKSFLD-LDKNISDggleavelvk
..|| ..||| ||| . ..|.. |..| ... .     .                               ||  .||||||  .|... .          
gkssvaffavfdghggreaakyarehleeilkeqksflele.............................kvekalrksfladtdeelks..........

kghsiR--SnegifaKlAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSGwepVALSKDQNVHNEEEVNRVKSAHPGEEDtvirESRLLGGLMPF
     .  .      . ..  ||..|. |.|.....||| .||.||||..| ..    ..|..|. . .|.|..|...|.   ..    . |. | |   
.....skan......t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn....ngrvngsLavs

RAFGDTEYKWPEeslshvhfvlgdyktPPYLTAEPVVTSYPSTGG-QFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSSK
||.||.|.|  |               ... .||| ||| . |   .||||..||||. ...|...|.| .. .|...... . .
RalGdfelkpke...............eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaee
PP2C Protein phosphatase 2C 105-385 4.6e-37 121.0 In-house 30-241 (255) alignment 
Range on Protein: 105-385
Range on HMM: 30-241/255.0
PESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVsgslnihrdgdtlldaggteslqlpdnsdKVPSLLRKSFLD-LDKNISDggleavelvk
..|| ..||| ||| . ..|.. |..| ... .     .                               ||  .||||||  .|... .          
gkssvaffavfdghggreaakyarehleeilkeqksflele.............................kvekalrksfladtdeelks..........

kghsiR--SnegifaKlAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSGwepVALSKDQNVHNEEEVNRVKSAHPGEEDtvirESRLLGGLMPF
     .  .      . ..  ||..|. |.|.....||| .||.||||..| ..    ..|..|. . .|.|..|...|.   ..    . |. | |   
.....skan......t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn....ngrvngsLavs

RAFGDTEYKWPEeslshvhfvlgdyktPPYLTAEPVVTSYPSTGG-QFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSSK
||.||.|.|  |               ... .||| ||| . |   .||||..||||. ...|...|.| .. .|...... . .
RalGdfelkpke...............eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaee
PPM_PTC7 104-381 5.3e-36 117.4 In-house 29-241 (259) alignment 
Range on Protein: 104-381
Range on HMM: 29-241/259.0
LPESSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVsgslnihrdgdtlldaggteslqlpdnsdKVPSLLRKSFLD--LDKNISDggleavel
 ...| ..||| ||| . ..|.. |..| ... .  .                                  |.   ||||||   .|... .        
sgkdsvaffavfdghggreaakyarehleeilkerksfeele.............................klekalrksflaldtdeelks........

vkkghsI--RsnegifaKlAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSGwepVALSKDQNVHNEEEVNRVKSAHPGEEDTviRESRLLGGLM
         .       . .   ||..|. |.|.....||| .||.||||... ..    ..|..|... ||.|..|...|.   ..   ...|. | | 
......sean.......t.epstsGstAvvalitgsklyvAnvGDSravLcrsgnav...kqltedHkpsnedEreRiegaggsvsnv..gngrvngvla

PFRAFGDTEYKWPEEslshvhfvlgdykTPPYLTAEPVVTSYPSTGG-QFLILGTDGLWERMKEQDIIDVVGRHYDKEgNKDK
  |||||.|.|  |              ......||| ..| . .   .||||..||||. . .|...|.| .. .|.  ...
vsRafGdfelkpket.............eeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlvrselskk.dpme
0049733 PP2C-like 92-445 2.6e-33 108.4 In-house 15-233 (235) alignment 
Range on Protein: 92-445
Range on HMM: 15-233/235.0
NSPNEDRYSFgglpesSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGGVVSgslnihrdgdtlldaggteslqlpdnsdkVPSLLRKSFLDLDKNI
.. |||.. .      . .|||| ||| . ...|.....|.... . |.|    .                             .  .|||.|| ... .
rkvneDavlv......glllfavaDGhgghaagevasellvetllelllelllld.............................leealrkaflaaneal

SDGgleavelvkkghsirsnegIFAKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKkagsGWEPVALSKDQNVHNEEEVNRVKSAHPGEedtvire
 .                      |    | .|..|. |.. ....|||. ||.||.| .    . . | |..|... ||.|. |...|..         
lel...................alaspelagmgtTavvalldggklyvanvGDsrayllr....dgklvqltedhspvnelerqriitaggav.......

sRLLGGLMPFRAFGDTEYKwpeeslshvhfvlgdyktppyltaePVVTSYPSTGGQFLILGTDGLWERMKEQDIIDVVGRhYDKegnkdktssktfglws
 | .|.|.  ||.||...|                         | ||... . | ||.| .||||. . ...|.|.. . .|                 
.rvpgrlaltralGdlllk.........................pdvtvlelepgdflllasDGlwdvlsdeeivdllrs.ldl................

skeKTCCEESVNSATEllweslggsdrsvkqlleipagmsRMYRDDITIIVIHF
   . ..|. |. | .                        |  ||.||..|...
...eeaaerlvelala........................rggrDNiTvvvvrl
subfamily_PPM1A_pd Subfamily PPM1A 95-445 1.8e-30 99.2 In-house 26-280 (282) alignment 
Range on Protein: 95-445
Range on HMM: 26-280/282.0
NEDRYSF-GGLPES-SAGLFAVIDGHRSFHCAEFLRQNLLKHVTQtlreggvvsgslnihrdgD----TlldaggteSLQLPDNSDKVPSLLRKSFLDLD
.||...    |..  . ..|||.|||   ..|..  ..||.....                  .             . .  ...|.| . ||..||.||
mEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..................eeelke........aaleasekdevkealrqgfLald

KNISDGGLEAVELvKKGhsirsnegifaklaqalsGACALFAMINPQTIYVASTGDCRAVLGKKAgsgwEPVALSKDQNVHNEEEVNRVKSAhpgeeDTV
..|..   .. .  .|                   |. |. ..........|  ||.|||| ..     . . |..|   ....| .|.. |     .  
eairelstdlkta.dks..................GsTavtvlvsekhliianlGDsRavlcrng....kaaflteDHkpsrpkEkkRieqA.....GGs

IRESRLLGGLMPFRAFGDTEYKWPEESLSHVHFVlgdyktppylTAEPVVTSYP-STGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTssktf
.  ||. | |   ||.|| |||  ||  ..   |          .||| |||   |.  .||.|  ||.|. .........| .....  .  .      
vvvsRvnGaLAvsRalGDyeykeeeekkaeeqlv..........saepevtsierseeddflvlacDGiwDvlsdeevvelvrkrlevadeleev.....

glwsskektcceesvnsatellweslggsdrsVKQLLEipAGMSRMYRDDITIIVIHF
                                .|.|..    ...  || ....|. |
................................akalvd..kalekgsrDNlsvlvvlf
subfamily_PPM1G2_pd Subfamily PPM1G2 107-384 1.4e-21 69.7 In-house 50-258 (287) alignment 
Range on Protein: 107-384
Range on HMM: 50-258/287.0
SSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQtlreggvvsgslnihrdgdtlldaggteslQLPDNSDKVPSLLRKSFLDLDKNISDGgleavelvkkgh
.|. |||| |||   ..|..  ..| | ...                              .   .....  .|...||..|...               
kslalfavfDGhGGakvakyagkklikkiak..............................kksfkegaleqilkdafletDeellkd............

sirsnegifAKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGsgwePVALSKDQNVHNEEEVNRVKSAhpgeeDTVIRESRLLGGLMPFRAFGD
          ||..  .|. |. ..|. . .||| .|| |||| .|.       ||| |   ..|.| .|.. |     . ..   |  | |   ||.||
.........eklkdesaGstavvvlikeeklyvanaGDsravlsskgn....vkalsfDhkPqeesekkriiaa.....gGfvelnrvngnLalsralgD

TEYKWPEEslshvhfvlgdyKT--PPYLTAEPVVTSYPST-GGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSS
 |.|  ..            |.      ||.| |.    .    ||.|  ||.|. .......|.|  .  .. . |. ..
fefkknvk............kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiie
subfamily_PPM1G_pd Subfamily PPM1G 223-377 1.2e-19 63.7 In-house 296-433 (473) alignment 
Range on Protein: 223-377
Range on HMM: 296-433/473.0
SGACALFAMINPQTIYVASTGDCRAVLGKKagsgWEPVALSKDQNVHNEEEVNRVKSAhpGeeDTVIRESRLLGGLMPFRAFGDTEYKWpEESLSHVHFV
||. |  |... ....||  ||.|.|| ..     . . || |    .|.| .|.. |  |   .|  . |. |||   ||.||  ||  .|.| .   .
sGttAvvaLlkekklivAnaGDsRcvlsrn....GkAldlslDHkPeDevEleRiekA..G..GkvdedgRvnGGLnlsRAlGDhaYkk.neeLplkeqm

lgdyktppyLTAEPVVTS-YPSTGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEG
         ..| | .      .  .||.| .||.|  |. |...| |  .  |. 
.........isAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvraklkkge
PPM_PTC7_SpoIIE 175-375 3e-16 52.9 In-house 68-211 (230) alignment 
Range on Protein: 175-375
Range on HMM: 68-211/230.0
KVPSLLRKSFLDLDKNISDGgleavelvkkghsirsnegifaklaQALSGACALFAMINPQT--IYVASTGDCRAVLGKKaGSGwepvalskdqnvhnee
|.  .||...| |.... |                           . |||.|..| |.|.|  .|||. ||....| .. . |                
kpeeilrrlnlalaadlede.........................psssgaTavvalidpstgklyvanaGdsppllvrd.dgg................

evN--RVksAHPGEEDtV-IRESRLLGGLMPFRAFGDTEYKWpeeslshvhfvlgdykTPPYLTAEPVvTSYPSTGG--QFLILGTDGLWERMKEQDIID
     |.  . .|  . . |.. |  | |   .|.||. ..                 |  . .|||  ||   . |  .||||..||||. .  |...|
..ereri..vagglps.lGilpgrvfgvlavslapGdlllly................tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvd

VVGRHYDK
 | .. .|
lvrdelek
subfamily_TAB1_pd Subfamily TAB1 218-362 2.4e-14 45.9 In-house 123-262 (333) alignment 
Range on Protein: 218-362
Range on HMM: 123-262/333.0
LAQAL-SGACALFAMINPQTIYVASTGDCRAVLGKKAGsGWEPVALSKDQNVHNEEEVNRVKSAhpGEEDTVIRESRLLGGLMPFRAFGDTEYKWPEESL
| . .  |. |. |.|  . .|||  || ||.| |.     . . ||.| .. ||.|. |.|    | .   |.. ..||. .. |. || . |   .  
leeeisgGttAvvalifnnkLyVaNvGdsrAllvkrke.sekvkqLsvdHttdNedEllRlkdL..GldieqikrnkrlgskentRsiGdykvkkgykdv

ShvhfVLGDYKTPPYLTAEPVVTSYPSTGGQF-LILGTDGLWERMKE
     .| . | .| ..   .. .|| .. .  |.|  ||. . ..|
d....ilssakgePviaePdiqgaypiddityflvlmSdGvyktLee
subfamily_PPM1L_pd Subfamily PPM1L 108-373 6.8e-13 41.5 In-house 34-236 (269) alignment 
Range on Protein: 108-373
Range on HMM: 34-236/269.0
SAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREGgvvsgslnihrdgdtlldaggteslqlpdnsdkvpsllrksflDLDKNISDGgLEAVELVK-KGH
.  .||| |||     ||| .. | | . . | |                                            | ||. .   ..  .|.. .  
gesffavfdGhGGefaaefakdvlvkaiknkliel...........................................dadkentep.infsklltdeil

SIRSNEGIFAKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSGwepVALSKDQNVHNEEEVNRVKSAhpGEEDTVIRESRLLGGLMPFRAFGD
|.  .    || |. ..|. || |... . . ||  || | ||  | |     . || |   .. .|  |.|.|  |   .     |. | |   ||.||
svdekllekakraediaGttalialvqesdlivanvGdsrGvlydkrGka...iplsfdhkpqqvkerkrikka..GGfiafrGvwrvaGvlatsralGd

teYkwPeesLSHVHFVLGDyktPPYLTAEpvvtsYPSTGGQFLILGTDGLWERMKEQDIIDVVGRHY
  |  |   | . ..|. |   |  || .           .|||| .||||. . ... .  .  . 
..y..p...lkdknlviad...pdiltfd.....lddhkpeflilasdGlwdtfsneeavrfikerl
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 221-378 1.3e-10 34.0 In-house 93-229 (255) alignment 
Range on Protein: 221-378
Range on HMM: 93-229/255.0
ALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSGwepVALSKDQNVHNEEEVNRVKSAHpGEEDTVIRESRLLGGLMPFRAFGDTeykwpeeslshvh
   |. |  ..|  . .|.|  || |.||..| |     . || | .  .|.| .|.. .  |   .    ||. | |   ||.||.             
kfiGttaasvliiedkvyianvGdsrvvlcqkdgta...krlsldhkPseeseekriselG.GtvvstvvtsrvnGtlavsralGds.............

fvlgdyKTPPYLTAEPVVT--SYPSTGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGN
         |.....| ..     |.  .||||  ||.|. . ... ...|    | |  
......flePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagisdpeka
subfamily_KAPP-like_pd Subfamily KAPP-like 107-385 1.6e-10 33.5 In-house 32-244 (266) alignment 
Range on Protein: 107-385
Range on HMM: 32-244/266.0
SSAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREggvvsgslnihrdgdtlldaggTESLQLPDNSDKVPSLLRKSFLDLDKNISDGGLE----AVELV
|  .||||.|||    .|.  .. . | . . |..                      |.  .  ||  .   ||...| ..|....|   |    .. ||
snialfavfdGhaGkGaadaakklfpkelekllks......................tkqddGGdniydqskllenafkevdaklkdfeyeGatatlalv

KKGHsirsnegifaklaqalsgacalfamiNPQTIYVASTGDCRAVLGKkagsGWEPVALSKDQNVHNEEEVNRVKSAHpgeeDTVIRESRLLGGLMPFR
 .                            . . . ||  ||  | | .    | | . |||| . ...||  |.|        |.  .   . ||.  |
wsdG..........................qqrylqvanvGdssaflsr....GneslelskdhkakdpeekqrikddG....itlsdnqtrinGlavsr

AFGDTEYKwpeeslshvHFVLGDyKTPPYLTAEPVVTSYpstgGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSSK
|.||   |         .  .|   . ||.. . ..| .     .|||. .||||. .. .| |..|   ||..  .|| .| 
alGdhfik.........elniGl.isepyvsnrilltpf....dkflivasdGlwdvisGkdaiekvkslydqqatedkmass
subfamily_ILKAP_pd Subfamily ILKAP 224-310 3.2e-09 29.4 In-house 114-197 (293) alignment 
Range on Protein: 224-310
Range on HMM: 114-197/293.0
GACALFAMINPQTIYVASTGDCRAVLGKKAGSGW--EPVALSKDQNVHNEEEVNRVKSAhpGeedTVIRESRLLGGLMPFRAFGDTEYK
|. |   ..  ...|||  || .||| .|  .|     |.|.|| .  ..|| .|.. |  |   .|.|..|.|| |   |. || ..|
GstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqka..G...gvvrdgrvlGvlevsrsiGdgrfk
subfamily_PPM1E_pd Subfamily PPM1E 322-383 5.4e-09 28.6 In-house 176-238 (265) alignment 
Range on Protein: 322-383
Range on HMM: 176-238/265.0
VLGDYKTPPYLTAEPVVTSYPSTGG-QFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTS
 .||.|. ||...|. |.... .|  ..|||..||||. ..|......|  .  .. .. .. 
aiGDvklkpyvsgeadvaeveldgseeylilacDGlwDvvneeevvklveefladgaedlsev
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 237-385 3.4e-08 25.7 In-house 128-254 (276) alignment 
Range on Protein: 237-385
Range on HMM: 128-254/276.0
IYVASTGDCRAVLGKkagsGWEPVALSKDQNVHNEEEVNRVKSAHpgeeDTVIRESRLLGGLMPFRAFGDTEYKwpeeslshvHFVLGDyKTPPYLTAEP
. ||  ||  | | .    | | . |||| .  . ||..|.|        |.  .   . ||.  ||.||   |         .  .|   . ||.. . 
lqvanvGdssaflsr....GneslelskdhkatdpeekqrikddG....itlsdnqtrinGlavsralGdhfik.........elniGl.isepyvsnri

VVTSYpstgGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDKTSSK
..| .     .|||. .||||. .. .| |..|   ||..  .|| .| 
lltpf....dkflivasdGlwdvisGkdaiekvkslydqqatedkmass
subfamily_PPM1D_pd Subfamily PPM1D 108-279 3.1e-07 22.8 In-house 34-166 (309) alignment 
Range on Protein: 108-279
Range on HMM: 34-166/309.0
SAGLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREggVVSGSLNIhrdgdtlldaggteslqlpdnsdkvpsllrksfldlDKNISDGGLEAVELVKKGHs
.   .||.|||   . |.| |..|.. ...      . | . ..                                     . |... |.  | .|| . 
evafvavfDGHGGkeAakfarehlwsvikkqkkf..lssepedv....................................leAireaflatheamkkkl.

irSNEGIFAKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAG--SGWEPVALSKDQNVHNEEEVNRVKS
  ..    ..   . .|. |   .|  . .|||  || ..|||.|    . ...  | ||   .. ||..|...
..eeWpktksgllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekeriee
PP2C_SIG_SM00331 190-444 4.5e-07 22.6 In-house 80-216 (217) alignment 
Range on Protein: 190-444
Range on HMM: 80-216/217.0
NisdggleavelvkkghsirsnegifakLAQALSGACALFAMI--NPQTIYVASTGDCRAVLGKkAGSGWEPVALskdqnvhneeevnrvksahpgeedt
.                                ..| .|.|..  . .....|. ||.| .|    |   |..                           
e...........................keekgmfaTlllalydfssgklsyanaGdsrpyllr.dgklveilkd.........................

viresrllgglmpfrafgdteykwpeeslsHVHFVLGDYKTPPyltaePVVTSYPSTGGQFLILGTDGLWERMKEQDiidvVGRHYDKEGNKDKTssktf
                                ...||  ....     . ...     | .|.| ||||.|...|..    ...  ..|  .|..     
..............................vegaplGlepevs.....vdirelelekgdllllytDGltearsekg....faeerleeiledlv.....

glwsskeKTCCEESVNSATELLWESLGGSDRsvkqlleipagmsrmyRDDITIIVIH
       .....|  .. .| | |...||                  .||||..|. 
.......dseaqelaqkiveellelakgsng................eDdiTvvvvk
PPM_PTC7_motif 350-379 6.4e-07 22.8 In-house 1-30 (51) alignment 
Range on Protein: 350-379
Range on HMM: 1-30/51.0
ILGTDGLWERMKEQDIIDVVGRHYDKEGNK
||..||||. ...|...|.| .. .|.|..
iLAsDGLWDvlsdqeavdlvrdqlskkgls
subfamily_PPM1K_pd Subfamily PPM1K 219-310 1.3e-06 20.7 In-house 94-182 (263) alignment 
Range on Protein: 219-310
Range on HMM: 94-182/263.0
AQALSGACALFAMI-NPQTIYVASTGDCRAVLGKKAgsgwEPVALSKDQNVHNEEEVNRVKSAHPGEEDTVIRESRLLGGLMPFRAFGDTEYK
 .  ||. |  ... . . . .||.|| ||.| ..     ..  |..| . . ||| .|.|.|    | . . . .. | |   |..|| . |
ellssGttatvsllrdGtelvlaslGdsrailcrnG....kakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGdldlk
PP2C_2 Protein phosphatase 2C 91-371 1.6e-06 20.6 Pfam-A 8-193 (212) alignment 
Range on Protein: 91-371
Range on HMM: 8-193/212.0
SNSPNEDRYSfgGLPESSAGLFAVIDGHRSFHC----AEFLRQNLLKHVTQTLREGGVVSgslnihrdGDTLL-----------Daggteslqlpdnsdk
...|..|..      .|.. |.||.||..|       |... ..........| |.   .         ..||           .               
kgkpcqDala..ireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe........eeallrqieneilasvk...............

vpsllrksfldldknisdggleavelvkkghsiR---SNEGifaKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSgWEPvaLSKDQNVHNEE
                                      ...   .      ..  |.|.|.|..|.... ||...|. ...|. ...  |.....   . 
.................................lkqeaeaq...qeelkdyatTlllavitpgeivffqiGDgaivvrdrdge.vql..lgepdsgeyan

EVNRVKSAHPGEEDtviresrllgglmpfrafgdteykwpeeslshvhfvlgdyktppyltaepVVTSYPSTGGQFLILGTDGLWERMKEQ-DIIDVVGR
|.....|. ..||                                                    . . .   |. |.| |||........ . ......
ettfltsedaeeel..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae
PP2C_2 Protein phosphatase 2C 91-371 1.6e-06 20.6 In-house 8-193 (212) alignment 
Range on Protein: 91-371
Range on HMM: 8-193/212.0
SNSPNEDRYSfgGLPESSAGLFAVIDGHRSFHC----AEFLRQNLLKHVTQTLREGGVVSgslnihrdGDTLL-----------Daggteslqlpdnsdk
...|..|..      .|.. |.||.||..|       |... ..........| |.   .         ..||           .               
kgkpcqDala..ireasdgwllaVADGaGsakrSdkGarlaveaagealeklleeeseqe........eeallrqieneilasvk...............

vpsllrksfldldknisdggleavelvkkghsiR---SNEGifaKLAQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSgWEPvaLSKDQNVHNEE
                                      ...   .      ..  |.|.|.|..|.... ||...|. ...|. ...  |.....   . 
.................................lkqeaeaq...qeelkdyatTlllavitpgeivffqiGDgaivvrdrdge.vql..lgepdsgeyan

EVNRVKSAHPGEEDtviresrllgglmpfrafgdteykwpeeslshvhfvlgdyktppyltaepVVTSYPSTGGQFLILGTDGLWERMKEQ-DIIDVVGR
|.....|. ..||                                                    . . .   |. |.| |||........ . ......
ettfltsedaeeel..................................................rirrlklepgdalllmTDGvsdslrkeepfrellae
subfamily_PPM1H_pd Subfamily PPM1H 290-381 2.2e-06 19.7 In-house 273-359 (404) alignment 
Range on Protein: 290-381
Range on HMM: 273-359/404.0
RESRLLGGLMPFRAFGDTEYKWPEESLSHVHFVLgdykTPPYLTAEPvVTSYPSTGGQFLILGTDGLWERMKEQDIIDVVGRHYDKEGNKDK
. .|||. .   | .|| | |  ...||   |.     . | ..    .|.. |.  . |||.|||||........  .| .  .|  ..||
kkaRllatigvtRGlGDheLkvvdtnlsikPfLs....pvPevrvld.ltqvesleDdvlilatDGLWdvlsneevaeivrevlskvepedk
subfamily_PPM1E_pd Subfamily PPM1E 221-310 4.2e-06 19.1 In-house 100-183 (265) alignment 
Range on Protein: 221-310
Range on HMM: 100-183/265.0
ALSGACALFAMINPQTIYVASTGDCRAVLGKKAgsgwEPVALSKDQNVHNEEEVNRVKSAhpGEEDTVIRESRLLGGLMPFRAFGDTEYK
  ||. |  ..|. ...|||  || .|.| .|     | | | |  .  .|.| .|...|  |    || . |  | |   || ||...|
lksGstavvvliekdqlyvaWlGDsqallvrkg....eavqlmkpHkPeredEkkRieea..gGlvvvigawRvnGvLsvsRaiGDvklk
subfamily_PPM1H_pd Subfamily PPM1H 110-266 4.3e-06 18.7 In-house 63-201 (404) alignment 
Range on Protein: 110-266
Range on HMM: 63-201/404.0
GLFAVIDGHRSFHCAEFLRQNLLKHVTQTLREggVVSGSLNIHRdgdtlldaggT--------EslqlPDNSDKVPSLLRKSFLDLDKNISdGGLEAVeL
 .|.. |||     |    ..| ||... |..  |.   |. ..          .        .    .... .|..  ... .  .. .  | ||    
ayfglfDGhaGsgaalvaskllhkhlkekled..vlellleksa..........eeeenteess....kespssvseiyeekeiskeeLvi.Galesa.f

VKKGHSIRSNEGIFaklaQALSGACALFAMINPQTIYVASTGDCRAVLGKKAGSgwepVALSKDQ
..  . |. ..  .    .   | .|| |..  . .|||  ||.||.| .|  .    ..||.| 
lemDeqiarereay....rikGGCtalvalvllgklYvanaGDsRailvrkdei....iplsadf
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 225-283 5.4e-06 19.1 In-house 87-147 (292) alignment 
Range on Protein: 225-283
Range on HMM: 87-147/292.0
ACALFAMINPQ-TIYVASTGDCRAVLGK-KAGSGWEPVALSKDQNVHNEEEVNRVKSAHPG
...  |... .  ...|  || ||.||.  .||  |.. ||.|   .. .| .|.. |   
tavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGr