Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPM1D_pd | Subfamily PPM1D | 6-328 | 9.5e-135 | 441.6 | In-house | 2-308 (309) | alignment | ||
Range on Protein: 6-328
Range on HMM: 2-308/309.0
ISAMAETNSGGRPYMEDYIAVYLSPKESLLsnplMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDSQSVREAISNAYLQLHNTMQESRASW
.|...|...|||.||||..|..|...||.. ..|.|||.||||||||||||.||.|||||...| |||......|.|||..|.|..|..|......|
lsvtseadqGgrkymeDvvaivleeeesae....elevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkleeW
APNKYGDLCTAGTTASTVIFRNNHIYVANVGDSTGIMGVRNPhfgepEEPLIIPKVLIKDHKPEDPEEQENTRRLGGEIALSlRGVMRVVWERERVESNE
...| |.|.|||||||.||.|....|||.||||. ..||..| .|. ...|.|.||||||.|||.|....||||.| . .||.||||.|.|.|.|.
pktksgllstaGttasvviirreklyvahvGDsaivlgvkep.....kekklrakeltkdHkPespeekerieelGGevaak.sGvkRvvWkRprlehng
KKVIDRWPFLGVTRSQGDIWSYSAQSGEYTVSPVPYVCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDTDSKGSCGNSSNsdtnvqRDVVSALIKE
..|||..||| |.||.||.|||.|.|||..|||.|.|... .| | ..||.|||||||||..| ..|........|... .... |.|..||.||
ptvideiPFLavaRslGDlWsynaksgefvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs......rsvakalvke
ALGRWSHMKLQADNIAVLIVYLS
||.||...||.|||..|..|.|.
alqrwrskklraDnvsvivvile
|
|||||||||
0034914 | PP2C-like | 6-328 | 9.1e-49 | 158.9 | In-house | 21-291 (295) | alignment | ||
Range on Protein: 6-328
Range on HMM: 21-291/295.0
ISAMAETNSGGRPYMEDYIAVYLspkesllsN--PLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQ----PKFLTQDSQSVREAISNAYLQLHNTMQ
... . .. | |...||.. |.| | .|.......|||||||| .||..|...|.. . .. .|| .. ...||. .|.|.... .
lrvgvasdqGrrksneDavlvvl........nllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeell
ESRASwapnkYGDLCTAGTTASTVIFRNNHIYVANVGDSTGIMGvRNPhfgepeepliIPKVLIKDHKPEDPEEQENTRRLGGEIALSLRGvmrvvwere
| . . .| . ||||.....|.|..|||||||| .. || .. | .|||| ...|.| ...|| . . .
elall.....rpelagsGtTavvalirgnklyvanvGDSravll.rng..........elvqltvdhkpvnelererilsaggavshgrvn.........
rvesnekkvidrwPFLGVTRSQGDIWSY---SAQSGEYTVSPVPYVCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISD----TDSkgscgnssnsdt
..| |||. || . . | |. ||..|.|. ....|. |..|||||||.|.|. |.|..... ...
.............gvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrsllakgld............
nvQRDVVSALIKEALGRWSHmklqaDNIAVLIVYLS
... .|...|| |.|. ||| |..|.|.
..leeaaeeLvdlAlargsr.....DNiTvvvvrln
|
|||||||||
PP2Cc_SM00332 | 11-325 | 9.9e-49 | 159.2 | In-house | 15-274 (274) | alignment | |||
Range on Protein: 11-325
Range on HMM: 15-274/274.0
ETNSGGRPYMEDYIAVYLSPKesllsnpLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQD-SQSVREAISNAYLQLHNTMQESRASWAPNK
.. | | ||| ..|... . . .|.||||||||.|.||.....|.. .....|. ... ...| ||...|.|.... . |. |. ...
ssmqgwrksmeDahvvvvdlv.......eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen
ygdlCTAGTTASTVIFRNNHIYVANVGDSTGIMGVRNPhfgepeepliiPKVLIKDHKPEDPEEQENTRRLGGeialslrgvmrvvwererveS---Nek
..|.||..........|||||||| ... . . | .||||||..| . .. || . .
....alsGstavvallkkedlyvanvGDSravlcrngk...........avqlsvdhkpedederkRikkagg....................vvekg..
KVIDRwpfLGVTRSQGDIWSYSAQ-SGEYTVSPVPYVCDFPIdLNVQRFIVLASDGLWNVMSPLEVVNFISDTDSKGscgnSSNSDTNVQRDVVSALIKE
.| . | |.|. || . .. . | ... | | . . .|..|||||||.|.|. |||... .. .|| . |. .... ... ..|.
rvngg...lavsrafGdhflkknkklkepyitaepdvkvvtl.tsedeflilaSDGlwdvlsnqevvdivrkllakg....ktndpqeaaelldeeairr
algrwshmKLQADNIAVLIV
. .||| |..|
........ggseDniTvvvv
|
|||||||||
PPM_PTC7 | 38-290 | 3.3e-48 | 157.4 | In-house | 29-238 (259) | alignment | |||
Range on Protein: 38-290
Range on HMM: 29-238/259.0
PLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDsqSVREAISNAYLQLHNTMQESRaswaP--NkyGDLCTAGTTASTVIFRNNHIYVANV
. ||..||||||| ||||||| ||. ...... | . . . .|.....|.|. . . . | | |.||..........|||||
sgkdsvaffavfdghggreaakyarehleeilkerksfeele..klekalrksflaldtdeelks....sean..tepstsGstAvvalitgsklyvAnv
GDSTGIMGVRNPHFgepeepliipKVLIKDHKPEDPEEQENTRRLGGEIALSlrGVMRVVWErervesnekkvidrwpfLGVTRSQGDIWSYSAQSGEYT
||| ... .. . | | .||||....| | ...||.. |. ||.. | |.|. || .... ...|
GDSravLcrsgnav..........kqltedHkpsnedEreRiegaggsvsnv..gngrvngv.................lavsRafGdfelkpketeeql
VSPVPYVCDFPIDLNvQRFIVLASDGLWNVMSPLEVVNFISDTDSKGscgnssnS
||. |... .|| . . |..|||||||.|.|. |.| .. .. ||. .
vsaePdisstkidee.defliLasdGlwdvvsdqeavdlvrselskk.......d
|
|||||||||
PP2C | Protein phosphatase 2C | 11-298 | 1.4e-47 | 155.4 | Pfam-A | 6-238 (255) | alignment | ||
Range on Protein: 11-298
Range on HMM: 6-238/255.0
ETNSGGRPYMEDYIAVYLSPKESllsnPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDsqSVREAISNAYLQlHNTMQESR--ASwapn
....| | ||| .. . . ..| . ||..||||||| ||||||| ||. ....|..||. . |..|.....|. . .. . |.
selqgarksmedahialknleks....sgkssvaffavfdghggreaakyarehleeilkeqksflele..kvekalrksfla.dtdeelksskan....
kYgDLCTAGTTASTVIFRNNHIYVANVGDSTGIMGVRNPHFgepeepliipKVLIKDHKPEDPEEQENTRRLGGEIALslrgVMRVVWErervesnekkv
. |.||.....|....|||||||| ... .. . | | .||||.|..| | ...||.. . ||..
.t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak..........keltedHkpsdedEreRIeeaggsvsn....ngrvngs...........
idrwpfLGVTRSQGDIWSYSAQsgEYTVSPVPYVCDFPIDLNvQRFIVLASDGLWNVMSPLEVVNFISDTDSKGScgnssnsdtnVQRDV
| |.|. || .... . |. ||. |.|. .... . |..|||||||.|.|. |.| .. .. ||.. ...
......LavsRalGdfelkpke..eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkk..........spmea
|
|||||||||
PP2C | Protein phosphatase 2C | 11-298 | 1.4e-47 | 155.4 | In-house | 6-238 (255) | alignment | ||
Range on Protein: 11-298
Range on HMM: 6-238/255.0
ETNSGGRPYMEDYIAVYLSPKESllsnPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDsqSVREAISNAYLQlHNTMQESR--ASwapn
....| | ||| .. . . ..| . ||..||||||| ||||||| ||. ....|..||. . |..|.....|. . .. . |.
selqgarksmedahialknleks....sgkssvaffavfdghggreaakyarehleeilkeqksflele..kvekalrksfla.dtdeelksskan....
kYgDLCTAGTTASTVIFRNNHIYVANVGDSTGIMGVRNPHFgepeepliipKVLIKDHKPEDPEEQENTRRLGGEIALslrgVMRVVWErervesnekkv
. |.||.....|....|||||||| ... .. . | | .||||.|..| | ...||.. . ||..
.t.epsksGstavvalirgkklyvAnvGDSravLcrkdnak..........keltedHkpsdedEreRIeeaggsvsn....ngrvngs...........
idrwpfLGVTRSQGDIWSYSAQsgEYTVSPVPYVCDFPIDLNvQRFIVLASDGLWNVMSPLEVVNFISDTDSKGScgnssnsdtnVQRDV
| |.|. || .... . |. ||. |.|. .... . |..|||||||.|.|. |.| .. .. ||.. ...
......LavsRalGdfelkpke..eqlvsaePdvtsvkltee.defliLasdGlwdvlsdqeavdlvrselskkk..........spmea
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 8-327 | 7.1e-39 | 126.8 | In-house | 14-280 (282) | alignment | ||
Range on Protein: 8-327
Range on HMM: 14-280/282.0
AMAETNSGGRPYMEDYIAVYLSpkesllsNPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKF-----LTQDSQSVREAISNAYLQLHNTMQESR
. ....| | ||| .| | . .....| |||||.|.|.|||. .|| . . .. .. .....|.||.....|.|.....|.
ygvssmqgwrvemEDahtvvas.......lgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairels
ASWAPNkygDLCtaGTTASTVIFRNNHIYVANVGDSTGIMgVRNPhfgepeepliIPKVLIKDHKPEDPEEQENTRRLGGEIAlslrgvmrvvW-----E
.. . | . |.|| ||. ...|...||.||| ... .|| . | .||||..|.|.. . ||..
tdlkta...dks..GsTavtvlvsekhliianlGDsRavl.crng..........kaaflteDHkpsrpkEkkRieqAGGsvv..........vsRvnGa
rervesnekkvidrwpfLGVTRSQGDIWSYS---AQSGEYTVSPVPYVCDFPIDLNVQrFIVLASDGLWNVMSPLEVVNFISDTDSKGSCGNSSnsdtnv
| |.|. || . .. | ||..|.| . .. . . |.|||.||.| |.| |||... .. .... ..
.................LAvsRalGDyeykeeeekkaeeqlvsaepevtsierseedd.flvlacDGiwDvlsdeevvelvrkrlevadeleev......
qrdvVSALIKEALGRWSHmklqaDNIAVLIVYL
..||...|| . |. ||..||.| .
....akalvdkalekgsr.....DNlsvlvvlf
|
|||||||||
0049733 | PP2C-like | 7-327 | 4.4e-35 | 114.2 | In-house | 4-233 (235) | alignment | ||
Range on Protein: 7-327
Range on HMM: 4-233/235.0
SAMAETNSGG-RPYMEDYIAVylspkesllsnplmrEQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFltQDSQSVREAISNAYLQLHNTMQESRASW
|. | . | |...||...| ......|.||||| .|...|...|....... . ... ...||. .|.|.... . | ..
svgaasdigrvrkvneDavlv...............glllfavaDGhgghaagevasellvetllellle..lllldleealrkaflaaneallelalas
ApnkygDLCTAGTTASTVIFRNNHIYVANVGDSTGIMGvRNPHfgepeepliiPKVLIKDHKPEDPEEQENTRRLGGEIalslrgvmrvvwerervesne
.| . ||||..........|||||||| .. |. . | .||.| ...|.. ...|| .
p.....elagmgtTavvalldggklyvanvGDsrayll.rdgk..........lvqltedhspvnelerqriitaggav.....................
kkviDRWPFLGVTRSQGDIWSYsaqsgeytvspvPYVCdfPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDTDSkgscgnssnsdtnvqRDVVSALIKE
. | .||. || . |.|. ..|. . |..|||||||.|.|. |.|......| ......|...
....rvpgrlaltralGdlllk............pdvt..vlelepgdflllasDGlwdvlsdeeivdllrsldl...............eeaaerlvel
ALGRWSHmklqaDNIAVLIVYL
|| |... ||| |..|.|
alarggr.....DNiTvvvvrl
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 15-328 | 1.7e-31 | 102.4 | In-house | 13-263 (265) | alignment | ||
Range on Protein: 15-328
Range on HMM: 13-263/265.0
GGRPYMEDYIAVYLSpKESLLSNPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDSqsvreaisnayLQLHNTMQESRASWAPNKYGDLC
. | ||| .. . ..|. ..|.|| .||||||| |||||| ||.... .|.|. .. .|...... . .
nkrrkmEDrhvaled.lnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa...........ealkeafkltDerflqkaerekl
TAGTTASTVIFRNNHIYVANVGDSTGIMgVRNPHFGEpeepliipkvLIKDHKPEDPEEQENTRRLGGEIALSlrGVMRVvwerervesNEKkvidrwpf
..|.|| .|. .....||| .||| ... ||. .. . |.| ||||...|.. .|| . |..|| |
ksGstavvvliekdqlyvaWlGDsqall.vrkgeavq..........lmkpHkPeredEkkRieeagGlvvvi..gawRv.........nGv........
LGVTRSQGDiwsysaQSGEYTVSPVPYVCDFPIDlNVQRFIVLASDGLWNVMSPLEVVNFISDTDSKgscgnssnsDTNVQRDVVSALIKEALGRWSHmk
| |.|. || .. . || . |.....| . . ...||.||||.|. . |||. ... .. ... . .| |...| . |.
LsvsRaiGD......vklkpyvsgeadvaeveld.gseeylilacDGlwDvvneeevvklveeflad.........gaedlsevakllveaakeagss..
lqaDNIAVLIVYLS
|||.|..|.|.
...Dnitvvvvfld
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 32-327 | 6.4e-31 | 100.3 | In-house | 41-286 (287) | alignment | ||
Range on Protein: 32-327
Range on HMM: 41-286/287.0
ESLLSNPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLtqdSQSVREAISNAYLQLHNTMQESraswapNKYGDlCTAGTTASTVIFRNNHIY
. ||... .. |...|||||||...|||| .| ........| ........ .|.|.. . ... .| | .||.|| .|. .....|
nelleksddkslalfavfDGhGGakvakyagkklikkiakkksfk...egaleqilkdafletDeellkd......eklkd.esaGstavvvlikeekly
VANVGDSTGIMGVRnphfGEpEepliipKVLIKDHKPEDPEEQENTRRLGGEIALSlRGVMRVVWERERVESNEKKVIDrwpflgvtrsqgdiwsysAQS
|||.||| .. .. |. | | ||||.. .|.. || ..| | . | . . || ..
vanaGDsravlssk....gn.v......kalsfDhkPqeesekkriiaagGfveln.rvngnLalsralgDfefkknvk..................kkp
GEYTVSPVPYVCDFPIDlNVQRFIVLASDGLWNVMSPLEVVNFISDTDSKGscgnsSNSDtnvqrDVVSALIKEALGRWSH-MKLQADNIAVLIVYL
| | || | .| . . |.||| ||.|.|.. |||... ..| . | .... |....| . |. . .||..|.|| |
eeqivtavPDvlvkkld.eddeflvLaCDGiWDvltnkevvdlvrerlvsg.....akld.....eiieelldkclapdssntgvGcDnmtvvivvl
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 8-327 | 1.1e-30 | 99.8 | In-house | 7-292 (293) | alignment | ||
Range on Protein: 8-327
Range on HMM: 7-292/293.0
AMAETNSGGRPYMEDYIAVYLSPK-ESLLSNPLMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQ-PKFL-TQDSQSVREAISNAYLQLHNTMQESRAS
.. | | |.| . . . .. |.. |. .. .|||||.|. |...| ..| .. .. || .. .... .. ... . . . . ..
gayaerkGereemqdahviledldeqlrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpksdvsakekeikkclvdsfkktdeefLklask
WAPnKYGDlctaGTTASTVIFRNNHIYVANVGDSTGIMGVRNPHFGEpeeplIIPKVLIKDHKPEdpeeqentrrlggeialslrgvmrVVWERERVESN
| .. | |.|| .|. .| .||||.||| .. .... . |. || |||.| ||.|..
akP.vWkd....GstatvvlvldnvlyvanlGdskavlvrkkeegdk.....iasvvLtkdhtpv........................kyeerkriqka
EKKVIDR--WPFLGVTRSQGDIwSYSaqsgEYTVSPVPYVCDFPIDLNvQRFIVLASDGLWNVMSPLEVVNFISDTDSKG-SCGNSSNSDTNVQRDVVSA
.| | |.|.|| || . . |. .| | .. | .|.||| ||||.|.| |||.||... . . . ...... ...|
GgvvrdgrvlGvlevsrsiGdg.rfk....rlGvistPdvkkceLten.dlfvvlaCdGLwkvfsadevvkfilkvledeeddrkikeeekkskeevrfe
LIKEALGRWSHMKLQADNIAVLIVYL
.. . | . . .||..||.| .
vacnrlaseavkrgssdnvtvllvki
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 14-280 | 1.3e-25 | 83.1 | In-house | 14-225 (255) | alignment | ||
Range on Protein: 14-280
Range on HMM: 14-225/255.0
SGGRPYMEDYIAVYLSPKESllsnplmREQAFVGVFDGHGGKEAAKYARDHLWSVVQNqpkFLTQDSQSVREAISNAYLQLHNTMqesraswapNKYGdl
| || ||| ...| | .. .. .. .||||||..|||.| ..| .... .| . . ... .|| ... . ....
iGrrptmedelviyGsfrdk.......sdedyyalfdGhgGraaakfaseelykilae...lldlnnanPvkslkkaykeistqi.........serp..
CTAGTTASTVIFRNNHIYVANVGDSTGIMGvrnphfgepeEPLIIPKVLIKDHKPEDPEEQENTRRLGGEIALSlrgvmrvvwerervesnekKVIDR-W
|||| .|.. ....|.|||||| ... . . | | |||| ...|.. ..||| . . .| |
kfiGttaasvliiedkvyianvGdsrvvlc..........qkdgtakrlsldhkPseeseekriselGGtvvst...................vvtsrvn
PFLGVTRSQGDIWSysaqsgEYTVSPVPYVCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDTDS
| |.|. ||.. | | | |.. . . ..|..|| ||.|...| | |. . . .
GtlavsralGdsfl......ePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivagisd
|
|||||||||
PPM_PTC7_SpoIIE | 38-281 | 1.8e-22 | 73.3 | In-house | 29-211 (230) | alignment | |||
Range on Protein: 38-281
Range on HMM: 29-211/230.0
PLMREQAFVGVFDGHGGKEaaKYARDHLWSVVQNQPkFLTQDsqSVREAISNAYLQLHNTMQESraswapnkygdLCTAGTTASTVIFRNNH--IYVANV
. | ..||..||||| . ..|. .|....... | . . . |......|.|. .... . |.||. ....... .||||.
sggrlalvvgdvdGhGgra..alamgllrtalrela.fagle..kpeeilrrlnlalaadlede...........psssgaTavvalidpstgklyvana
GDSTGIMGVRNPHfgepeepliipkvlikdhkpedpeeqENTRRlGGEIALS--L-RGvmRVVWErervesnekkvidrwpfLGVTRSQGDIWSYSaqsG
||| .. ... | .| .. ..| . | ||... | |... ||.. .
Gdsppllvrddgg..........................ereri.vagglpslGilpg..rvfgv.................lavslapGdlllly...t
EYTVSPVPYvCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDTDSK
. |.. |. . .. ....|..|||||||.|.|| |.| .. |. .|
DGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelek
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 15-285 | 4.4e-22 | 71.6 | In-house | 14-242 (269) | alignment | ||
Range on Protein: 15-285
Range on HMM: 14-242/269.0
GGRPYMEDYIAVYLSPKESllsnplmREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDSqSVREAISNAYLQLHNTMQESRASWAPNKYgDLC
| || ||| . . |.. .. |..|||||||. ||..|.| | ..|. . | .| | |. . | .. . . |
Grrprmedrfeieediknk.......tgesffavfdGhGGefaaefakdvlvkaiknklieldadk.entepinfsklltdeilsvdekllekakr.aed
TAGTTASTVIFRNNHIYVANVGDSTGIMGVRNphfGEpeeplIIPkvLIKDHKPEDPEEQENTRRLGGEIAlsLRGVMRVvwerervESnekkvidrwpF
.||||| . ..... ||||||| |.. .. |. || | ||||....|. .. || || .||| || .
iaGttalialvqesdlivanvGdsrGvlydkr...Gk.....aip..lsfdhkpqqvkerkrikkaGGfia..frGvwrv.......aG..........v
LGVTRSQGDiwsYSAQSGEyTVSPVPYVCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDTDSKGSCG
| ..|. || | . . | . | . | .| .|..|||||||. .| | |.|| . .. |
latsralGd...yplkdkn.lviadpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfG
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 40-278 | 4.1e-20 | 65.0 | In-house | 28-228 (263) | alignment | ||
Range on Protein: 40-278
Range on HMM: 28-228/263.0
MREQAFVGVFDGHGGKEAAKYARDHLWSVVQnqpkFLTQDSQSVREAISNAYLQLHNTMQESRASWAPNKygDLCTAGTTASTVIFRN-NHIYVANVGDS
| .|.|||||.| ||... |.| ... .| . . ... . ||...|.. .. ... .| ..||||. ...|. ... .|..|||
dpellyvavfdGhaGsaaadfvhdklekilk....rllekekdleivlknafeeldkklkrylefsvaea..ellssGttatvsllrdGtelvlaslGds
TGIMgVRNphfGEpeepliiPKVLIKDHKPEDPEEQENTRRLGGEIALSLRGVMRVvwerervESNekkvidrwpfLGVTRSQGDIwsysaQSGEYTVSP
|. || |. .| | .||.|| ||.| .. || .. . | ..| .. | .||| ||. . .| |
rail.crn...Gk.......akkltrdhdPeleeekerikaagGsvewnslgkplv.......ngr..........lamtrslGdl.....dlkryGvia
VPYVCDFPIDLNVQRFIVLASDGLWNVMSPLEVVNFISDT
| . .| . . |.|| .||. .|.. |. ....
tPetkslkvdhaadsflvlitdgisfvvnsqelcdlvrlc
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 45-200 | 4.7e-16 | 52.2 | In-house | 22-169 (292) | alignment | ||
Range on Protein: 45-200
Range on HMM: 22-169/292.0
F-VGVFDGHG--GKEAAKYARDHLWSVVQNqpkfLTQDSQSVREAISNAYLQLHNTMQESRASwapnkygDLCTAGTTASTVIFRNN-HIYVANVGDSTG
| |.|||| |.. |..| |.| . . ||.. | . ||. . |.. .... . |.|.. . |.. ...||||||
flaavldGhGvnGdkvaqlaedtlevelle....ltrqlqelsealllrildiaakldkltid.......aresattavvcarvrddralilanvGdsra
IMGVRnphFGEPEEPLiIPkvLIKDHKPEDPEEQENTRRLGGEIA------LSLRGVMRVvWERER
..| .| . | || | .|||||||.|.. .| || . || || | | .
llgrc...lggsdyel.iP..lsrdhkPedPderarilraGGrveptrvrgwgfrGtarv.wrrrq
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 41-99 | 5e-10 | 32.0 | In-house | 45-100 (473) | alignment | ||
Range on Protein: 41-99
Range on HMM: 45-100/473.0
REQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFltqDSQSVREAISNAYLQLHNTMQ
. .. .|.||||||| ||| ..| ....| . . |..|...|.|.| ....
edtslfavyDGHGGkevakyvakklpdllkaqkgy...kegdvekaleeaflalDeklk
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 18-178 | 9.8e-10 | 30.9 | In-house | 10-155 (266) | alignment | ||
Range on Protein: 18-178
Range on HMM: 10-155/266.0
PYMED-YIAVYLSPKESLLSNplMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLTQDsqSVREAISNAYLQLHNTMQESRASWAPNKYgDLCTA
||| ..|.| || ||| . |. .||||| || ||. |.. . ..... | || . | . |.|...| | .| . .||
temedvslaiypllkekklsn..csnialfavfdGhaGkGaadaakklfpkelekllkstkqd..dGGdniydqskllenafkevdaklkdfey.eGata
GTTASTVIFRNNHIYVANVGDSTGIMGVRNphfgepeEPLiipkVLIKDHKPEDPEEQENTR
. . .. |||||||. .. | | | | |||| .||||. .
tlalvwsdGqqrylqvanvGdssaflsrGn.......esl....elskdhkakdpeekqrik
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 116-189 | 2.1e-09 | 29.9 | In-house | 296-358 (473) | alignment | ||
Range on Protein: 116-189
Range on HMM: 296-358/473.0
AGTTASTVIFRNNHIYVANVGDSTGIMGVRnphfgepeeplIIPKVLIKDHKPEDPEEQENTRRLGGEIALSLR
.|||| .. ......|||.||| .. | ||||||..|.| .. ||.. .|
sGttAvvaLlkekklivAnaGDsRcvlsrn...........GkAldlslDHkPeDevEleRiekAGGkvdedgR
|
|||||||||
subfamily_Dicty-PPM1L-like_pd | Subfamily Dicty-PPM1L-like | 41-138 | 5.5e-09 | 28.3 | In-house | 35-137 (305) | alignment | ||
Range on Protein: 41-138
Range on HMM: 35-137/305.0
REQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKFLT--------QDSQSVREAISNAYLQLHNTMQESraSWAPNKYGDLCTAGtTASTVIFRNNHIYV
.|. . ||||||.|. ||.|.. .| .| . | ... |||..|.|. . . .| . . || . | ....||. .. . |
qelslfGvfdGhnGdiaaeyvkkklveivnkyvkenkvGysaknlnvddlpleaiksaslstdksslds..aesdnkkaGttlng.ssasvilerertiv
ANVGDS
.. .|.
stasdt
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 75-148 | 2.2e-08 | 26.6 | In-house | 107-184 (398) | alignment | ||
Range on Protein: 75-148
Range on HMM: 107-184/398.0
FLTQDSQSVREAISNAYLQLHNTMQESRASWAPNKYG----DLCTAGTTASTVIFRNNHIYVANVGDSTGIMGVRNPH
| . ..|.||...|.|.| . ... . ...| . ..|..| .. ......|||.||. ..||....
lleaevekvkealkkaFlklDkdistealkklkekslreallvalsGacallaliegtelhvAntGDcravlgvqeee
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 252-306 | 9.6e-08 | 24.4 | In-house | 402-448 (473) | alignment | ||
Range on Protein: 252-306
Range on HMM: 402-448/473.0
QRFIVLASDGLWNVMSPLEVVNFISDTDSKGSCGnssnsdtnVQRDVVSALIKEA
. |.|||.||.||||. |||.|. . .||. | ..| .|. ..
deFlvlAcDGiWnvmesqevvdfvraklkkgees........vlseiveeLlDac
|
|||||||||
PPM_PTC7_motif | 256-278 | 1.1e-07 | 25.2 | In-house | 1-23 (51) | alignment | |||
Range on Protein: 256-278
Range on HMM: 1-23/51.0
VLASDGLWNVMSPLEVVNFISDT
.|||||||.|.|. |.|... |.
iLAsDGLWDvlsdqeavdlvrdq
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 18-178 | 1.9e-07 | 23.2 | In-house | 9-165 (276) | alignment | ||
Range on Protein: 18-178
Range on HMM: 9-165/276.0
PYMED-YIAVYLSPKESLLSNplMREQAFVGVFDGHGGKEAAKYARDHLWSVVQNQPKF----LTQDSQSVrEAISNAYLQLHNTMQESRASWAPNKYGD
||| ..|.| .| ||| . |. .||||| || ||. |.. . ... | ||.. . . | . | . ..| | .|
temedvslaiyplldekdlsn..csnialfavfdGhaGkGaadaakklfpkelekllksgnysltkqddGG.dniydqskllldlfkevdaklkdfeyeG
lCTAGTtasTVIF---------RNNHIYVANVGDSTGIMGVRNphfgepeEPLiipkVLIKDHKPEDPEEQENTR
.|| .... .. .. |||||||. .. | | | | |||| .||||.. .
.atatl...alvwsdGeeqqqqqqrylqvanvGdssaflsrGn.......esl....elskdhkatdpeekqrik
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 251-299 | 2.8e-07 | 23.0 | In-house | 284-333 (398) | alignment | ||
Range on Protein: 251-299
Range on HMM: 284-333/398.0
VQRFIVLASDGLWNVMSPLEVVNFISDTDSKGSCGNSS-NSDTNVQRDVV
..|.|||.||||...|. |||. ... .| .. ...... |
ndkFLvlatDGLwdllsneevvslVgehlakkkekepvkveeakltlkqv
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 230-278 | 2.1e-06 | 19.7 | In-house | 258-305 (492) | alignment | ||
Range on Protein: 230-278
Range on HMM: 258-305/492.0
QSGEYTVSPVPYVCDFPIDLNVQrFIVLASDGLWNVMSPLEVVNFISDT
. . .| | |.. ..| . | |.|||| |||.|.| ||.. . .|
pkLkksvipePkttsvkldeaaq.flvlAsnGlWevlseeevlsLvkqt
|
|||||||||
subfamily_TAB1_pd | Subfamily TAB1 | 116-184 | 3e-06 | 19.2 | In-house | 129-189 (333) | alignment | ||
Range on Protein: 116-184
Range on HMM: 129-189/333.0
AGTTASTVIFRNNHIYVANVGDSTGIMGVRNPhfgepEEPLiipKVLIKDHKPEDPEEQENTRRLGGEI
|||| .. ||..|||||||| .. |.. .| | | .||. . ..| . ..|| .|
gGttAvvalifnnkLyVaNvGdsrAllvkrke.....sekv...kqLsvdHttdNedEllRlkdLGldi
|
|||||||||
PP2C_SIG_SM00331 | 43-140 | 8e-06 | 18.6 | In-house | 30-112 (217) | alignment | |||
Range on Protein: 43-140
Range on HMM: 30-112/217.0
QAFVGVFDGHG-GKEAAKYARDhLWSVVQNQPKFLTQDSQSVREAISNAYLQlhntmqesraswapnkyGDLCTAGTTASTVI--FRNNHIYVANVGDST
. .. |.||.| |..|| ... | ...... . . || ...... .| . . . ..|. . |.......||.|||
rlllvvaDgmGkGlaAaaassq.lrtalrellsegeelsqalkrlnraiyee.................keekgmfaTlllalydfssgklsyanaGdsr
G
p
|