Gene TAB1-3 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP214_AA protein Get Run
AqueP214_AA_34-356 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TAB1_pd Subfamily TAB1 37-357 4.3e-64 209.4 In-house 8-332 (333) alignment
Range on Protein: 37-357
Range on HMM: 8-332/333.0
SSQTRNNEDRYYSGCQGNIQ-LCMVLDGHQGESAAEFTVLSLAGKILSES-----RIEDPKLLLERVFRETEDSFFVGMDDPIGRRLALKAELNQRPAGG
|..  ..||. .  .  | . |  | ||..|..||.|    |  ..| |        ...|  |.| | |.| .|.  .|| .  .  |. .| .  .  
skedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekddlqsqlPegvssy

SFERHRDLQQDELRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
  |.. . . . |. |...| |||| |. ||  ||.|| ||.|||||.|... .       ||| ||.. |..|  |||.||||| |. . .|||  . |
eleeqypekierlqeleeeisgGttAvvalif.nnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldieqikrnkrlgskent

RSIGDYLIKGGYTEVDVLRSASQGPGIATPFVNGPWDISNLQnkTFLILMSDGLYEAYGSCINTRNpPELHSsLARLVMDEMRLHNRLDRVGQAVVNRVK
|||||| .|.||..||.| ||.. |.||.| ..|...| ...   ||.|||||.|..     .. .  .... ..  |. |.  .  |. | ||||..||
RsiGdykvkkgykdvdilssakgePviaePdiqgaypiddit..yflvlmSdGvyktLeevtgpet.snven.illevitelekqatlqdvAqavvdkvk

EQYREICRR-----DRKDGKLDDMTLIIQNFT
 . ..          .   | |||||.. .| 
rkHkdaylssaseravicrkrddmtllvlkfe

PP2Cc_SM00332 35-353 2.8e-31 101.9 In-house 16-273 (274) alignment
Range on Protein: 35-353
Range on HMM: 16-273/274.0
GQSSQTRNNEDRYYSGCQ----GNIQLCMVLDGHQGESAAEFTVLSLAGKILSESR-IE-----DPKLLLERVFRETEDSFFVGMDDPI--Grrlalkae
 .  . ...||.. .  .     .  .. | ||| |...|.|.   |   . .|    .     |.. .|...|..|.. .    .              
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen........

lnqrpaggsferhrdlqqdelrrldsqIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLlqlR
                              |.|.|..|.. ...|| ||.||||||||...|     | ||| ||......| .|.|| |  . .    |
...........................alsGstavvallk.kedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkaggvvekg...r

RLGPFQITRSIGDYLIKGGYtevdvlrsA----------------SqgpgiatpfvngpwdisnLQNKTFLILMSDGLYEaygscinTRNPPELHSSLAR
  |  ...|..||.  |                                                ... ||||.||||..         .. |... . .
vngglavsrafGdhflkknk........klkepyitaepdvkvvtl..................tsedeflilaSDGlwd.......vlsnqevvdivrk

LVMDEmrlhnrldrvgqaVVNRVKEQYREICRRDRKD-GKLDDMTLII
| . .             . |...|   ....  ... |. |..| ..
llakg.............ktndpqeaaelldeeairrggseDniTvvv

0034914 PP2C-like 40-356 6.3e-31 100.4 In-house 32-290 (295) alignment
Range on Protein: 40-356
Range on HMM: 32-290/295.0
TRNNEDRYYSGC-----QGNIQLCMVLDGHQGESAAEFTVLSLAGKILSE---------SRIEDPKLLLERVFRETEDSFFVGMDDPigrrlalkaelnq
 ..|||...  .     .... |. | ||| | .|||.    |   .|..         . .||..  |...| ...  ..    .              
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr.............

rpaggsferhrdlqqdelrrlDSQIEGGTTVVLSLItTNNQLYTANIGDSRAVLCeedKNGriIASQLSDDHNVFNPEEQDRLKKLGLDIGQllqLRRLG
                      . . .|||.|. || ..|.||.||.|||||||.   .||   . ||. ||.. |..|. |....|  .      |..|
.....................pelagsGtTavvali.rgnklyvanvGDSravll...rng..elvqltvdhkpvnelererilsaggavsh...grvng

PFQITRSIGDYLIKGGYTEvdvlrSASQGPGIATPFVNgpWDISNLQNKTFLILMSDGLYEAYGscintrnppelHSSLARLVMDEMRLHNRLDRVGQAV
 ...||..||.  |  ..       ... . .|.| |   .   .|..  ||.|.||||..              .. ....|.. .. .. |. . ...
vlavtRalGdfdlklllsl.....llleplvsaePdvt..vleltledddfllLasDGlwdvls...........neeivdivrsllakgldleeaaeeL

VNRVKEqyreicrrdrkDGKLDDMTLIIQNF
|... .            |. |..| ..  .
vdlAla...........rgsrDNiTvvvvrl

PPM_PTC7 135-287 2.3e-27 89.1 In-house 80-220 (259) alignment
Range on Protein: 135-287
Range on HMM: 80-220/259.0
HRDLQQDELRRLD----SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
.. |..||  ...      . .|.| |. ||| .. ||.||.||||||||  ...      ||. ||.. |..| .|....|  . .  . |  | .. .
flaldtdeelksseantepstsGstAvvalitgsk.lyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavs

RSIGDYLIKGGYTevdvlrsaSQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEA
|..||.  | ..|        .. . .|.| ..    . .  .  ||||.||||.. 
RafGdfelkpket........eeqlvsaePdis...stkideedefliLasdGlwdv

PP2C Protein phosphatase 2C 140-288 2.5e-27 89.1 Pfam-A 84-216 (255) alignment
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.||  ..  .  ...  |.| |..||. .. ||.||.||||||||  |..      .|. || . ...| .|....|  . .  . |  | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd

YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| ..          . . .| | |.    ..  ..  ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl

PP2C Protein phosphatase 2C 140-288 2.5e-27 89.1 In-house 84-216 (255) alignment
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.||  ..  .  ...  |.| |..||. .. ||.||.||||||||  |..      .|. || . ...| .|....|  . .  . |  | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd

YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| ..          . . .| | |.    ..  ..  ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl

0049733 PP2C-like 40-353 6.4e-26 84.3 In-house 15-230 (235) alignment
Range on Protein: 40-353
Range on HMM: 15-230/235.0
TRNNEDRYYSgcqgNIQLCMVLDGHQGESAAEFT---VLSLAGKILSESRIEDPKLLLERVFRETEDSFFVGmddpigrrlalkaelnqrpaggsferhr
 ..|||...     .. |. | ||| |  |.|.    ....  ..| |  ..|.. .|...|..... ..                              
rkvneDavlv....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallel............................

dlqqdeLRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIgqllqlRRLGPFQITRSIGDY
       ..  .   .|||.|. |.. ...||.||.|||||.|. ..|     . ||. ||...|..|. |....|  .      | .|  ..||..||.
......alaspelagmgtTavvalld.ggklyvanvGDsrayllrdgk.....lvqltedhspvnelerqriitaggav......rvpgrlaltralGdl

LIKggytevdvlrsasqgpgiatpfvnGPWDISNLQNKTFLILMSDGLYEAygscintR------------NPPELHSSLARLVMDemrlhnrldrvgqa
|.|                          . . .|..  ||.|.||||..                     .. |. . |..|...              
llk........................pdvtvlelepgdflllasDGlwdv.......lsdeeivdllrsldleeaaerlvelala..............

vvnrvkeqyreicrrdrkDGKLDDMTLII
                   |. |..|...
..................rggrDNiTvvv

subfamily_PPM1A_pd Subfamily PPM1A 40-288 5.7e-24 77.9 In-house 23-234 (282) alignment
Range on Protein: 40-288
Range on HMM: 23-234/282.0
TRNNEDRYYSGCQG----NIQLCMVLDGHQGESAAEFTVLSLAGKILSESRIEDpklllervfretedsffvgmddpigrrlA-----LKAELNQRPAGG
 ...||..   ..     . ..  |.||| |...|...   | ..||.|.....                            |      | |...    |
rvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelke............................aaleasekdevkealrqg

SFERHR--------------DlqqdelrrldsqiegGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiG
 .. .                               |.|.|  |.. ...|..||.||||||||.. |     |  |..||   .|.|..|... |   |
fLaldeairelstdlktadks...............GsTavtvlvs.ekhliianlGDsRavlcrngk.....aaflteDHkpsrpkEkkRieqAG...G

QLLQLRRLGPFQITRSIGDYLIKGGYTEVDVLRSASqgpgiATPFVNgpwDISNLQNKTFLILMSDGLYEAY
...  |  |   ..|..||| .|   .     .  |     | | |.    |.  ....||.| .||...  
svvvsRvnGaLAvsRalGDyeykeeeekkaeeqlvs.....aepevt...sierseeddflvlacDGiwDvl

subfamily_PPM1G2_pd Subfamily PPM1G2 54-289 8.6e-17 54.0 In-house 51-235 (287) alignment
Range on Protein: 54-289
Range on HMM: 51-235/287.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesriedpklllervfretedsffvgmddpigRRLALKAELNQRPAGGSFERHRDLQQDelRRLDSQIEGG
...|  |.||| |...|...   |  || .                               ..   . .|.|    .  |  ..|..|  ..|. .  | 
slalfavfDGhGGakvakyagkklikkiak...............................kksfkegaleqilkdafletDeellkd..eklkdesaGs

TTVVlSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDYLIKGGYTevdvlRSASQ
|.||  ||. ...|| ||.|||||||... .     ...|| ||   . .|. |... |   |     |  |   . |..||.  | . .      .. .
tavv.vlik.eeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkriiaag...GfvelnrvngnLalsralgDfefkknvk.....kkpee

GPGIATPFVNGpWDISnlQNKTFLILMSDGLYEAYG
    |.| |    ...  ... ||.|  ||... . 
qivtavPDvlv.kkld..eddeflvLaCDGiWDvlt

subfamily_PPM1L_pd Subfamily PPM1L 54-289 9.1e-17 54.2 In-house 34-224 (269) alignment
Range on Protein: 54-289
Range on HMM: 34-224/269.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesRIEDPklllervfretedsffvgmddpigrrlaLKAELNQRPAG-GSFERHRDLQQD--ELRRLDSQI
..... | ||| || ||||.   |. .|..  .. .                              ..  |. |   . .  .. |  |   | .. .. 
gesffavfdGhGGefaaefakdvlvkaikn..kliel............................dadkentepinfsklltdeilsvdekllekakrae

-EGGTTVVLSLITtNNQLYTANIGDSRAVLCeeDKNGRIIasQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIKggytEVDVLr
 . |||....|.. ...|  ||.|||| ||.  ||.|. |   || ||   ...|. |.|| |  |      |  | . ..|..||| .|    . ... 
diaGttalialvq.esdlivanvGdsrGvly..dkrGkai..plsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk....dknlv.

sasqgpgIATPFVNGpWDISNLQnKTFLILMSDGLYEAYG
       ||.| .   .|. ...   |||| ||||.... 
.......iadpdilt.fdlddhk.peflilasdGlwdtfs

subfamily_PDP_pd Subfamily PDP 151-287 1.5e-16 53.5 In-house 151-298 (398) alignment
Range on Protein: 151-287
Range on HMM: 151-298/398.0
EGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQ---LLQLRRLGPFQITRSIGDYLIKGGY-TEVD
  |.. .|.||  .. |. ||.||.||||. ....|   | .|| |... |.||  |.||   .  .   . . | ||  | .|  ||.  |    ..  
lsGacallaliegte.lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkk

VLRSA---SQGP-GI-ATPFVNGPWDISNLQ---NKTFLILMSDGLYEA
||..|    . |    . |..    .. . .   |. ||.| .|||.. 
vlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwdl

subfamily_ILKAP_pd Subfamily ILKAP 152-288 2e-16 53.0 In-house 113-230 (293) alignment
Range on Protein: 152-288
Range on HMM: 113-230/293.0
GGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKNGR-IIASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDylikGGYTEVDVlrs
 |.|... |.  .| ||.||.|||.|||.  ...|. |.. .|. ||.  . ||. |..| |   |.. . | || ....|||||    | . .. |   
dGstatvvlv.ldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGd....grfkrlGv...

asqgpgIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
      |.||.|.    .   .|  |..|  |||....
......istPdvk...kceLtendlfvvlaCdGLwkvf

subfamily_PPM1G_pd Subfamily PPM1G 151-241 6.6e-14 44.7 In-house 295-377 (473) alignment
Range on Protein: 151-241
Range on HMM: 295-377/473.0
EGGTTVVLSLITTnNQLYTANIGDSRAVLCEEdkngrIIASQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKGG
. ||| |  |. . ..|. ||.||||.||...       | .|| ||   ...|..|..| |  . .  ..|  |   . | .||.  |  
dsGttAvvaLlke.kklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvde..dgRvnGGLnlsRAlGDhaYkkn

PPM_PTC7_SpoIIE 141-290 6.8e-14 45.2 In-house 87-172 (230) alignment
Range on Protein: 141-290
Range on HMM: 87-172/230.0
DelrrldsQIEGGTTVVLSLITTNN-QLYTANIGDSRAVLCEEDKNgriiasqlsddhnvfnpeEQDRLkKLGLDIGqL--L-QlRRLGPFQITRSIGDY
.        ...|.|.|. ||. .. .||.|| |||...|.  |.                   |  |. ..|  .  |  | . |  | .......||.
e.......psssgaTavvalidpstgklyvanaGdsppllvrddgg..................ereri.vagglps.lGilpg.rvfgvlavslapGdl

LIKGgytevdvlrsasqgpgiatpfvngpwdisnlqnktflilmSDGLYEAYGS
|..                                         .||. ||   
llly........................................tDGvveaepd

subfamily_PPM1D_pd Subfamily PPM1D 56-215 9.3e-14 44.2 In-house 36-171 (309) alignment
Range on Protein: 56-215
Range on HMM: 36-171/309.0
QLCMVLDGHQGESAAEFTVLSLAGKILSESRIedpkL------LlervfretedsffvgmddpigrrlalKAELNQRPAGGSFERHRDLQQDELRRLDSQ
    | ||| |. ||.|.   | ..|  .. .    |      .                           . ...       . .. |..   ..    
afvavfDGHGGkeAakfarehlwsvikkqkkf....lssepedv..........................leAireaflatheamkkkleeWpktksgll

IEGGTTVVLsLITTNNQLYTANIGDSRAVLCEEDK-NGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
   |||. . .| ....||.|..|||..||  ... . ...|..| .||   .|||. |...|| ..
staGttasv.viirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGev

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 150-239 4.4e-13 42.1 In-house 93-178 (255) alignment
Range on Protein: 150-239
Range on HMM: 93-178/255.0
IEGGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKngriIASQLSDDHNVFNPEEQDRLKKLGLDIGQL-LQLRRLGPFQITRSIGDYLIK
.  ||| .  || .... | ||.||||.|||. |     .| .|| ||.  ...|. |...||  . .     |  | . ..|..||  ..
kfiGttaasvli.iedkvyianvGdsrvvlcqkdg....takrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle

subfamily_PPM1K_pd Subfamily PPM1K 134-239 4.6e-13 41.9 In-house 84-182 (263) alignment
Range on Protein: 134-239
Range on HMM: 84-182/263.0
RHRDLQQDELrrldSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCeedKNGRiiASQLSDDHNVFNPEEQDRLKKLGLDI--GQLLQLRRLGPFQITR
|.  ..  |     .. . |||  .||.   ..|  |..|||||.||   .||.  |..|..||.    ||..|.|. |  .    | ...  | . .||
rylefsvaea....ellssGttatvsllrdGtelvlaslGdsrailc...rnGk..akkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtr

SIGDYLIK
|.||  .|
slGdldlk

subfamily_KAPP-like_pd Subfamily KAPP-like 129-287 1.4e-12 40.2 In-house 73-218 (266) alignment
Range on Protein: 129-287
Range on HMM: 73-218/266.0
GGSFERHRDLQQDELRRLDSQI-----EGGTtVVLSLITT-NNQLY--TANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQ
| .    ..| .. .. .|...     || |   |.|. .  .| |  .||.||| | |.  ..   .   .|| ||.  .|||. |.|. |. . .  .
GdniydqskllenafkevdaklkdfeyeGat.atlalvwsdGqqrylqvanvGdssaflsrGne..sl...elskdhkakdpeekqrikddGitlsd..n

LRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVNGPWDISNLqnKTFLILMSDGLYEA
  |.    ..|..||..||    |  . .         |..|.|  .. ..    . |||. ||||.. 
qtrinGlavsralGdhfik....elniGl.........isepyvsnrilltpf..dkflivasdGlwdv

subfamily_PPM1E_pd Subfamily PPM1E 148-239 6.1e-12 38.3 In-house 98-183 (265) alignment
Range on Protein: 148-239
Range on HMM: 98-183/265.0
SQIEGGTTVVLSLITTnNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIK
 ....|.| |  ||.. .||| | .|||.|.|... .     | || . |.  ...|..|....|  . .. ..|  |  ...|.|||.  |
eklksGstavvvliek.dqlyvaWlGDsqallvrkge.....avqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 166-287 2.5e-10 32.7 In-house 127-228 (276) alignment
Range on Protein: 166-287
Range on HMM: 127-228/276.0
QLYTANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVN
 | .||.||| | |.  ..   .   .|| ||.  .|||..|.|. |. . .  .  |.    ..|..||..||    |  . .         |..|.| 
ylqvanvGdssaflsrGne..sl...elskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfik....elniGl.........isepyvs

GPWDISNLqnKTFLILMSDGLYEA
 .. ..    . |||. ||||.. 
nrilltpf..dkflivasdGlwdv

subfamily_PPM1H_pd Subfamily PPM1H 59-219 3.7e-10 32.1 In-house 66-221 (404) alignment
Range on Protein: 59-219
Range on HMM: 66-221/404.0
MVLDGHQGESAAEFTVLSLAGKIlsESRIEDPKLLLERVFRETEDSFFVGM-DDPIGRRLAL-KAEL-NQRPAGGSFERHRDLQQDE--LRRLDSQIEGG
 . ||| |..||  ..  |  ..  ....|| . || .  .|.|. .     ..|  ..    . |. ...   |..|       .     | . .|.||
glfDGhaGsgaalvaskllhkhl..kekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqiarereayrikGG

TTVVLSLItTNNQLYTANIGDSRAVLCEEDKNgriiaSQLSDDHNvfnPE-EQDRLKKLGLDIGQLL
 |.. .|.  ...|| || |||||.|...|.       .|| |.    || |. ||..|.    .||
Ctalvalv.llgklYvanaGDsRailvrkdei.....iplsadft...PeteRqRlqelaflkPeLl

PP2C_SIG_SM00331 47-353 3e-09 29.8 In-house 20-214 (217) alignment
Range on Protein: 47-353
Range on HMM: 20-214/217.0
YYSGCQGNI--QLCMVLDGHQGESAAEFTVLSLAGKILSESRI-EDPKLLLERVFRETEDSffvgmddpigrrlalkaelnqrpaggsferhrdlqqdel
||   . |   .|..| ||. .  ||.    .| ...  ...  |... .|.|. |  ..                                        
yydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellsegeelsqalkrlnraiyee.......................................

rrlDSQIEGGTTVVLSLI-TTNNQLYTANIGDSRAVLCEEDKNGRIIASqlsddhnvfnpeeqdrlkklgldigqllqlrrlgpfqitrsigdylikggy
   .   ....|..| |. .....|. ||.|||| .|  ..|   |. .                                                   
...keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd...................................................

tevdvlrsasQ-----------GpgiatpfvngpWDISNLQ--NKTFLILMSDGLYEAYGSCIntRNPPELHSSLARLVmdemrlHNRLDRVGQavvnrv
          .                        ||..|.   . .|.|..||| ||  .     .  .|   |. ||      .. .....|      
..........vegaplGlepevs...........vdirelelekgdllllytDGltearsekg..faeerleeiledlv......dseaqelaq......

kEQ------------YreicrrdrkdgkLDDMTLII
 .             .             ||.|...
.kiveellelakgsng............eDdiTvvv

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 146-215 5.2e-09 29.0 In-house 79-148 (292) alignment
Range on Protein: 146-215
Range on HMM: 79-148/292.0
LDSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
.| . ...|.|| . .  . .|. ||.|||||.|       .     || ||   .|.|. |... |  .
idaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrv

PP2C_2 Protein phosphatase 2C 39-307 8.7e-07 21.4 Pfam-A 8-194 (212) alignment
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
.  ...|...   . . .|..| ||.   . ..      |   ||. |...      .. . ||... .| . |                          
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................

sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
      . |. | ..  .  . .||..| .|| ..... ..|||...|. ..|.. ... .. | ..     |    .   ..      |          
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........

rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
                                             .|..  |.  . |.||.||. ...      |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael

PP2C_2 Protein phosphatase 2C 39-307 8.7e-07 21.4 In-house 8-194 (212) alignment
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
.  ...|...   . . .|..| ||.   . ..      |   ||. |...      .. . ||... .| . |                          
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................

sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
      . |. | ..  .  . .||..| .|| ..... ..|||...|. ..|.. ... .. | ..     |    .   ..      |          
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........

rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
                                             .|..  |.  . |.||.||. ...      |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael

subfamily_PP2D1_pd Subfamily PP2D1 165-217 1.3e-06 20.5 In-house 188-235 (492) alignment
Range on Protein: 165-217
Range on HMM: 188-235/492.0
NQLYTANIGDSRAVLCEEdknGRiiASQLSDDHNVFNPEEQDRLKKLGLDIGQ
  || ||.|. .|||| |   |.  | .|  .|.  |..| .|..| |  . .
gvlyianaGnvqAvLcre...Gk..aiiLtreHtprnkkERtRvekagsvvvk