Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_TAB1_pd | Subfamily TAB1 | 37-357 | 4.3e-64 | 209.4 | In-house | 8-332 (333) | alignment | ||
Range on Protein: 37-357
Range on HMM: 8-332/333.0
SSQTRNNEDRYYSGCQGNIQ-LCMVLDGHQGESAAEFTVLSLAGKILSES-----RIEDPKLLLERVFRETEDSFFVGMDDPIGRRLALKAELNQRPAGG
|.. ..||. . . | . | | ||..|..||.| | ..| | ...| |.| | |.| .|. .|| . . |. .| . .
skedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddalaekddlqsqlPegvssy
SFERHRDLQQDELRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
|.. . . . |. |...| |||| |. || ||.|| ||.|||||.|... . ||| ||.. |..| |||.||||| |. . .||| . |
eleeqypekierlqeleeeisgGttAvvalif.nnkLyVaNvGdsrAllvkrke..sekvkqLsvdHttdNedEllRlkdLGldieqikrnkrlgskent
RSIGDYLIKGGYTEVDVLRSASQGPGIATPFVNGPWDISNLQnkTFLILMSDGLYEAYGSCINTRNpPELHSsLARLVMDEMRLHNRLDRVGQAVVNRVK
|||||| .|.||..||.| ||.. |.||.| ..|...| ... ||.|||||.|.. .. . .... .. |. |. . |. | ||||..||
RsiGdykvkkgykdvdilssakgePviaePdiqgaypiddit..yflvlmSdGvyktLeevtgpet.snven.illevitelekqatlqdvAqavvdkvk
EQYREICRR-----DRKDGKLDDMTLIIQNFT
. .. . | |||||.. .|
rkHkdaylssaseravicrkrddmtllvlkfe
|
|||||||||
PP2Cc_SM00332 | 35-353 | 2.8e-31 | 101.9 | In-house | 16-273 (274) | alignment | |||
Range on Protein: 35-353
Range on HMM: 16-273/274.0
GQSSQTRNNEDRYYSGCQ----GNIQLCMVLDGHQGESAAEFTVLSLAGKILSESR-IE-----DPKLLLERVFRETEDSFFVGMDDPI--Grrlalkae
. . ...||.. . . . .. | ||| |...|.|. | . .| . |.. .|...|..|.. . .
smqgwrksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen........
lnqrpaggsferhrdlqqdelrrldsqIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLlqlR
|.|.|..|.. ...|| ||.||||||||...| | ||| ||......| .|.|| | . . |
...........................alsGstavvallk.kedlyvanvGDSravlcrngk.....avqlsvdhkpedederkRikkaggvvekg...r
RLGPFQITRSIGDYLIKGGYtevdvlrsA----------------SqgpgiatpfvngpwdisnLQNKTFLILMSDGLYEaygscinTRNPPELHSSLAR
| ...|..||. | ... ||||.||||.. .. |... . .
vngglavsrafGdhflkknk........klkepyitaepdvkvvtl..................tsedeflilaSDGlwd.......vlsnqevvdivrk
LVMDEmrlhnrldrvgqaVVNRVKEQYREICRRDRKD-GKLDDMTLII
| . . . |...| .... ... |. |..| ..
llakg.............ktndpqeaaelldeeairrggseDniTvvv
|
|||||||||
0034914 | PP2C-like | 40-356 | 6.3e-31 | 100.4 | In-house | 32-290 (295) | alignment | ||
Range on Protein: 40-356
Range on HMM: 32-290/295.0
TRNNEDRYYSGC-----QGNIQLCMVLDGHQGESAAEFTVLSLAGKILSE---------SRIEDPKLLLERVFRETEDSFFVGMDDPigrrlalkaelnq
..|||... . .... |. | ||| | .|||. | .|.. . .||.. |...| ... .. .
rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr.............
rpaggsferhrdlqqdelrrlDSQIEGGTTVVLSLItTNNQLYTANIGDSRAVLCeedKNGriIASQLSDDHNVFNPEEQDRLKKLGLDIGQllqLRRLG
. . .|||.|. || ..|.||.||.|||||||. .|| . ||. ||.. |..|. |....| . |..|
.....................pelagsGtTavvali.rgnklyvanvGDSravll...rng..elvqltvdhkpvnelererilsaggavsh...grvng
PFQITRSIGDYLIKGGYTEvdvlrSASQGPGIATPFVNgpWDISNLQNKTFLILMSDGLYEAYGscintrnppelHSSLARLVMDEMRLHNRLDRVGQAV
...||..||. | .. ... . .|.| | . .|.. ||.|.||||.. .. ....|.. .. .. |. . ...
vlavtRalGdfdlklllsl.....llleplvsaePdvt..vleltledddfllLasDGlwdvls...........neeivdivrsllakgldleeaaeeL
VNRVKEqyreicrrdrkDGKLDDMTLIIQNF
|... . |. |..| .. .
vdlAla...........rgsrDNiTvvvvrl
|
|||||||||
PPM_PTC7 | 135-287 | 2.3e-27 | 89.1 | In-house | 80-220 (259) | alignment | |||
Range on Protein: 135-287
Range on HMM: 80-220/259.0
HRDLQQDELRRLD----SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQIT
.. |..|| ... . .|.| |. ||| .. ||.||.|||||||| ... ||. ||.. |..| .|....| . . . | | .. .
flaldtdeelksseantepstsGstAvvalitgsk.lyvAnvGDSravLcrsgnav....kqltedHkpsnedEreRiegaggsvsnvgngrvngvlavs
RSIGDYLIKGGYTevdvlrsaSQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEA
|..||. | ..| .. . .|.| .. . . . ||||.||||..
RafGdfelkpket........eeqlvsaePdis...stkideedefliLasdGlwdv
|
|||||||||
PP2C | Protein phosphatase 2C | 140-288 | 2.5e-27 | 89.1 | Pfam-A | 84-216 (255) | alignment | ||
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.|| .. . ... |.| |..||. .. ||.||.|||||||| |.. .|. || . ...| .|....| . . . | | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd
YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| .. . . .| | |. .. .. ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl
|
|||||||||
PP2C | Protein phosphatase 2C | 140-288 | 2.5e-27 | 89.1 | In-house | 84-216 (255) | alignment | ||
Range on Protein: 140-288
Range on HMM: 84-216/255.0
QDELRRL--D--SQIEGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGriiaSQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGD
.|| .. . ... |.| |..||. .. ||.||.|||||||| |.. .|. || . ...| .|....| . . . | | .. .|..||
tdeelksskantepsksGstavvalirgkk.lyvAnvGDSravLcrkdnak....keltedHkpsdedEreRIeeaggsvsn..ngrvngsLavsRalGd
YLIKGGYtevdvlrsasQGPGIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
. .| .. . . .| | |. .. .. ||||.||||.. .
felkpke..........eqlvsaePdvt...svklteedefliLasdGlwdvl
|
|||||||||
0049733 | PP2C-like | 40-353 | 6.4e-26 | 84.3 | In-house | 15-230 (235) | alignment | ||
Range on Protein: 40-353
Range on HMM: 15-230/235.0
TRNNEDRYYSgcqgNIQLCMVLDGHQGESAAEFT---VLSLAGKILSESRIEDPKLLLERVFRETEDSFFVGmddpigrrlalkaelnqrpaggsferhr
..|||... .. |. | ||| | |.|. .... ..| | ..|.. .|...|..... ..
rkvneDavlv....glllfavaDGhgghaagevasellvetllelllelllldleealrkaflaaneallel............................
dlqqdeLRRLDSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIgqllqlRRLGPFQITRSIGDY
.. . .|||.|. |.. ...||.||.|||||.|. ..| . ||. ||...|..|. |....| . | .| ..||..||.
......alaspelagmgtTavvalld.ggklyvanvGDsrayllrdgk.....lvqltedhspvnelerqriitaggav......rvpgrlaltralGdl
LIKggytevdvlrsasqgpgiatpfvnGPWDISNLQNKTFLILMSDGLYEAygscintR------------NPPELHSSLARLVMDemrlhnrldrvgqa
|.| . . .|.. ||.|.||||.. .. |. . |..|...
llk........................pdvtvlelepgdflllasDGlwdv.......lsdeeivdllrsldleeaaerlvelala..............
vvnrvkeqyreicrrdrkDGKLDDMTLII
|. |..|...
..................rggrDNiTvvv
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 40-288 | 5.7e-24 | 77.9 | In-house | 23-234 (282) | alignment | ||
Range on Protein: 40-288
Range on HMM: 23-234/282.0
TRNNEDRYYSGCQG----NIQLCMVLDGHQGESAAEFTVLSLAGKILSESRIEDpklllervfretedsffvgmddpigrrlA-----LKAELNQRPAGG
...||.. .. . .. |.||| |...|... | ..||.|..... | | |... |
rvemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelke............................aaleasekdevkealrqg
SFERHR--------------DlqqdelrrldsqiegGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiG
.. . |.|.| |.. ...|..||.||||||||.. | | |..|| .|.|..|... | |
fLaldeairelstdlktadks...............GsTavtvlvs.ekhliianlGDsRavlcrngk.....aaflteDHkpsrpkEkkRieqAG...G
QLLQLRRLGPFQITRSIGDYLIKGGYTEVDVLRSASqgpgiATPFVNgpwDISNLQNKTFLILMSDGLYEAY
... | | ..|..||| .| . . | | | |. |. ....||.| .||...
svvvsRvnGaLAvsRalGDyeykeeeekkaeeqlvs.....aepevt...sierseeddflvlacDGiwDvl
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 54-289 | 8.6e-17 | 54.0 | In-house | 51-235 (287) | alignment | ||
Range on Protein: 54-289
Range on HMM: 51-235/287.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesriedpklllervfretedsffvgmddpigRRLALKAELNQRPAGGSFERHRDLQQDelRRLDSQIEGG
...| |.||| |...|... | || . .. . .|.| . | ..|..| ..|. . |
slalfavfDGhGGakvakyagkklikkiak...............................kksfkegaleqilkdafletDeellkd..eklkdesaGs
TTVVlSLITtNNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDYLIKGGYTevdvlRSASQ
|.|| ||. ...|| ||.|||||||... . ...|| || . .|. |... | | | | . |..||. | . . .. .
tavv.vlik.eeklyvanaGDsravlsskgn.....vkalsfDhkPqeesekkriiaag...GfvelnrvngnLalsralgDfefkknvk.....kkpee
GPGIATPFVNGpWDISnlQNKTFLILMSDGLYEAYG
|.| | ... ... ||.| ||... .
qivtavPDvlv.kkld..eddeflvLaCDGiWDvlt
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 54-289 | 9.1e-17 | 54.2 | In-house | 34-224 (269) | alignment | ||
Range on Protein: 54-289
Range on HMM: 34-224/269.0
NIQLCMVLDGHQGESAAEFTVLSLAGKILSesRIEDPklllervfretedsffvgmddpigrrlaLKAELNQRPAG-GSFERHRDLQQD--ELRRLDSQI
..... | ||| || ||||. |. .|.. .. . .. |. | . . .. | | | .. ..
gesffavfdGhGGefaaefakdvlvkaikn..kliel............................dadkentepinfsklltdeilsvdekllekakrae
-EGGTTVVLSLITtNNQLYTANIGDSRAVLCeeDKNGRIIasQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIKggytEVDVLr
. |||....|.. ...| ||.|||| ||. ||.|. | || || ...|. |.|| | | | | . ..|..||| .| . ...
diaGttalialvq.esdlivanvGdsrGvly..dkrGkai..plsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk....dknlv.
sasqgpgIATPFVNGpWDISNLQnKTFLILMSDGLYEAYG
||.| . .|. ... |||| ||||....
.......iadpdilt.fdlddhk.peflilasdGlwdtfs
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 151-287 | 1.5e-16 | 53.5 | In-house | 151-298 (398) | alignment | ||
Range on Protein: 151-287
Range on HMM: 151-298/398.0
EGGTTVVLSLITTNNqLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDIGQ---LLQLRRLGPFQITRSIGDYLIKGGY-TEVD
|.. .|.|| .. |. ||.||.||||. ....| | .|| |... |.|| |.|| . . . . | || | .| ||. | ..
lsGacallaliegte.lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkk
VLRSA---SQGP-GI-ATPFVNGPWDISNLQ---NKTFLILMSDGLYEA
||..| . | . |.. .. . . |. ||.| .|||..
vlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwdl
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 152-288 | 2e-16 | 53.0 | In-house | 113-230 (293) | alignment | ||
Range on Protein: 152-288
Range on HMM: 113-230/293.0
GGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKNGR-IIASQLSDDHNVFNPEEQDRLKKLGldiGQLLQLRRLGPFQITRSIGDylikGGYTEVDVlrs
|.|... |. .| ||.||.|||.|||. ...|. |.. .|. ||. . ||. |..| | |.. . | || ....||||| | . .. |
dGstatvvlv.ldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaG...gvvrdgrvlGvlevsrsiGd....grfkrlGv...
asqgpgIATPFVNgpwDISNLQNKTFLILMSDGLYEAY
|.||.|. . .| |..| |||....
......istPdvk...kceLtendlfvvlaCdGLwkvf
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 151-241 | 6.6e-14 | 44.7 | In-house | 295-377 (473) | alignment | ||
Range on Protein: 151-241
Range on HMM: 295-377/473.0
EGGTTVVLSLITTnNQLYTANIGDSRAVLCEEdkngrIIASQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKGG
. ||| | |. . ..|. ||.||||.||... | .|| || ...|..|..| | . . ..| | . | .||. |
dsGttAvvaLlke.kklivAnaGDsRcvlsrn.....GkAldlslDHkPeDevEleRiekAGGkvde..dgRvnGGLnlsRAlGDhaYkkn
|
|||||||||
PPM_PTC7_SpoIIE | 141-290 | 6.8e-14 | 45.2 | In-house | 87-172 (230) | alignment | |||
Range on Protein: 141-290
Range on HMM: 87-172/230.0
DelrrldsQIEGGTTVVLSLITTNN-QLYTANIGDSRAVLCEEDKNgriiasqlsddhnvfnpeEQDRLkKLGLDIGqL--L-QlRRLGPFQITRSIGDY
. ...|.|.|. ||. .. .||.|| |||...|. |. | |. ..| . | | . | | .......||.
e.......psssgaTavvalidpstgklyvanaGdsppllvrddgg..................ereri.vagglps.lGilpg.rvfgvlavslapGdl
LIKGgytevdvlrsasqgpgiatpfvngpwdisnlqnktflilmSDGLYEAYGS
|.. .||. ||
llly........................................tDGvveaepd
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 56-215 | 9.3e-14 | 44.2 | In-house | 36-171 (309) | alignment | ||
Range on Protein: 56-215
Range on HMM: 36-171/309.0
QLCMVLDGHQGESAAEFTVLSLAGKILSESRIedpkL------LlervfretedsffvgmddpigrrlalKAELNQRPAGGSFERHRDLQQDELRRLDSQ
| ||| |. ||.|. | ..| .. . | . . ... . .. |.. ..
afvavfDGHGGkeAakfarehlwsvikkqkkf....lssepedv..........................leAireaflatheamkkkleeWpktksgll
IEGGTTVVLsLITTNNQLYTANIGDSRAVLCEEDK-NGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
|||. . .| ....||.|..|||..|| ... . ...|..| .|| .|||. |...|| ..
staGttasv.viirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGev
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 150-239 | 4.4e-13 | 42.1 | In-house | 93-178 (255) | alignment | ||
Range on Protein: 150-239
Range on HMM: 93-178/255.0
IEGGTTVVLSLItTNNQLYTANIGDSRAVLCEEDKngriIASQLSDDHNVFNPEEQDRLKKLGLDIGQL-LQLRRLGPFQITRSIGDYLIK
. ||| . || .... | ||.||||.|||. | .| .|| ||. ...|. |...|| . . | | . ..|..|| ..
kfiGttaasvli.iedkvyianvGdsrvvlcqkdg....takrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 134-239 | 4.6e-13 | 41.9 | In-house | 84-182 (263) | alignment | ||
Range on Protein: 134-239
Range on HMM: 84-182/263.0
RHRDLQQDELrrldSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCeedKNGRiiASQLSDDHNVFNPEEQDRLKKLGLDI--GQLLQLRRLGPFQITR
|. .. | .. . ||| .||. ..| |..|||||.|| .||. |..|..||. ||..|.|. | . | ... | . .||
rylefsvaea....ellssGttatvsllrdGtelvlaslGdsrailc...rnGk..akkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtr
SIGDYLIK
|.|| .|
slGdldlk
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 129-287 | 1.4e-12 | 40.2 | In-house | 73-218 (266) | alignment | ||
Range on Protein: 129-287
Range on HMM: 73-218/266.0
GGSFERHRDLQQDELRRLDSQI-----EGGTtVVLSLITT-NNQLY--TANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQ
| . ..| .. .. .|... || | |.|. . .| | .||.||| | |. .. . .|| ||. .|||. |.|. |. . . .
GdniydqskllenafkevdaklkdfeyeGat.atlalvwsdGqqrylqvanvGdssaflsrGne..sl...elskdhkakdpeekqrikddGitlsd..n
LRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVNGPWDISNLqnKTFLILMSDGLYEA
|. ..|..||..|| | . . |..|.| .. .. . |||. ||||..
qtrinGlavsralGdhfik....elniGl.........isepyvsnrilltpf..dkflivasdGlwdv
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 148-239 | 6.1e-12 | 38.3 | In-house | 98-183 (265) | alignment | ||
Range on Protein: 148-239
Range on HMM: 98-183/265.0
SQIEGGTTVVLSLITTnNQLYTANIGDSRAVLCEEDKngriiASQLSDDHNVFNPEEQDRLKKLGLDIGQLLQLRRLGPFQITRSIGDYLIK
....|.| | ||.. .||| | .|||.|.|... . | || . |. ...|..|....| . .. ..| | ...|.|||. |
eklksGstavvvliek.dqlyvaWlGDsqallvrkge.....avqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 166-287 | 2.5e-10 | 32.7 | In-house | 127-228 (276) | alignment | ||
Range on Protein: 166-287
Range on HMM: 127-228/276.0
QLYTANIGDSRAVLCEEDKngRIiasQLSDDHNVFNPEEQDRLKKLGLDIGQllQLRRLGPFQITRSIGDYLIKggytE--VDVlrsasqgpgIATPFVN
| .||.||| | |. .. . .|| ||. .|||..|.|. |. . . . |. ..|..||..|| | . . |..|.|
ylqvanvGdssaflsrGne..sl...elskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfik....elniGl.........isepyvs
GPWDISNLqnKTFLILMSDGLYEA
.. .. . |||. ||||..
nrilltpf..dkflivasdGlwdv
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 59-219 | 3.7e-10 | 32.1 | In-house | 66-221 (404) | alignment | ||
Range on Protein: 59-219
Range on HMM: 66-221/404.0
MVLDGHQGESAAEFTVLSLAGKIlsESRIEDPKLLLERVFRETEDSFFVGM-DDPIGRRLAL-KAEL-NQRPAGGSFERHRDLQQDE--LRRLDSQIEGG
. ||| |..|| .. | .. ....|| . || . .|.|. . ..| .. . |. ... |..| . | . .|.||
glfDGhaGsgaalvaskllhkhl..kekledvlellleksaeeeenteesskespssvseiyeekeiskeeLviGalesaflemDeqiarereayrikGG
TTVVLSLItTNNQLYTANIGDSRAVLCEEDKNgriiaSQLSDDHNvfnPE-EQDRLKKLGLDIGQLL
|.. .|. ...|| || |||||.|...|. .|| |. || |. ||..|. .||
Ctalvalv.llgklYvanaGDsRailvrkdei.....iplsadft...PeteRqRlqelaflkPeLl
|
|||||||||
PP2C_SIG_SM00331 | 47-353 | 3e-09 | 29.8 | In-house | 20-214 (217) | alignment | |||
Range on Protein: 47-353
Range on HMM: 20-214/217.0
YYSGCQGNI--QLCMVLDGHQGESAAEFTVLSLAGKILSESRI-EDPKLLLERVFRETEDSffvgmddpigrrlalkaelnqrpaggsferhrdlqqdel
|| . | .|..| ||. . ||. .| ... ... |... .|.|. | ..
yydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellsegeelsqalkrlnraiyee.......................................
rrlDSQIEGGTTVVLSLI-TTNNQLYTANIGDSRAVLCEEDKNGRIIASqlsddhnvfnpeeqdrlkklgldigqllqlrrlgpfqitrsigdylikggy
. ....|..| |. .....|. ||.|||| .| ..| |. .
...keekgmfaTlllalydfssgklsyanaGdsrpyllrdgklveilkd...................................................
tevdvlrsasQ-----------GpgiatpfvngpWDISNLQ--NKTFLILMSDGLYEAYGSCIntRNPPELHSSLARLVmdemrlHNRLDRVGQavvnrv
. ||..|. . .|.|..||| || . . .| |. || .. .....|
..........vegaplGlepevs...........vdirelelekgdllllytDGltearsekg..faeerleeiledlv......dseaqelaq......
kEQ------------YreicrrdrkdgkLDDMTLII
. . ||.|...
.kiveellelakgsng............eDdiTvvv
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 146-215 | 5.2e-09 | 29.0 | In-house | 79-148 (292) | alignment | ||
Range on Protein: 146-215
Range on HMM: 79-148/292.0
LDSQIEGGTTVVLSLITTNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNVFNPEEQDRLKKLGLDI
.| . ...|.|| . . . .|. ||.|||||.| . || || .|.|. |... | .
idaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrv
|
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PP2C_2 | Protein phosphatase 2C | 39-307 | 8.7e-07 | 21.4 | Pfam-A | 8-194 (212) | alignment | ||
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
. ...|... . . .|..| ||. . .. | ||. |... .. . ||... .| . |
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................
sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
. |. | .. . . .||..| .|| ..... ..|||...|. ..|.. ... .. | .. | . .. |
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........
rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
.|.. |. . |.||.||. ... |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael
|
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PP2C_2 | Protein phosphatase 2C | 39-307 | 8.7e-07 | 21.4 | In-house | 8-194 (212) | alignment | ||
Range on Protein: 39-307
Range on HMM: 8-194/212.0
QTRNNEDRYYSGCQGNIQLCMVLDGHQGESAAEF----TVLsLAGKILSESR----IEDPKLLLERVFRETEDSFFvgmddpigrrlalkaelnqrpagg
. ...|... . . .|..| ||. . .. | ||. |... .. . ||... .| . |
kgkpcqDalaireasdgwllaVADGaGsakrSdkGarlave.aagealeklleeeseqeeeallrqieneilasvk........................
sferhrDLQQDELRRLdSQIEGGTTVVLSLITtNNQLYTANIGDSRAVLCEEDKNGRIIASQLSDDHNvfnPEeqdrL---KK------Lgldigqllql
. |. | .. . . .||..| .|| ..... ..|||...|. ..|.. ... .. | .. | . .. |
......lkqeaeaqqe.elkdyatTlllavit.pgeivffqiGDgaivvrdrdgevqllgepdsgeya...ne....ttfltsedaeeel..........
rrlgpfqitrsigdylikggytevdvlrsasqgpgiatpfvngpwDISN--LQNKTFLILMSDGLYEAYgscintRNPPELHSSLARL
.|.. |. . |.||.||. ... |....... ||.|
.............................................rirrlklepgdalllmTDGvsdsl......rkeepfrellael
|
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subfamily_PP2D1_pd | Subfamily PP2D1 | 165-217 | 1.3e-06 | 20.5 | In-house | 188-235 (492) | alignment | ||
Range on Protein: 165-217
Range on HMM: 188-235/492.0
NQLYTANIGDSRAVLCEEdknGRiiASQLSDDHNVFNPEEQDRLKKLGLDIGQ
|| ||.|. .|||| | |. | .| .|. |..| .|..| | . .
gvlyianaGnvqAvLcre...Gk..aiiLtreHtprnkkERtRvekagsvvvk
|