Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_TAB1_pd | Subfamily TAB1 | 172-514 | 1.8e-158 | 519.6 | In-house | 1-332 (333) | alignment | ||
Range on Protein: 172-514
Range on HMM: 1-332/333.0
SVINCRYSitetselsaDPDHYNEDRVFFAKTDDVI-VMAVFDGHDGNKASGLVEQYLFSKFINPDVLVGL-RFETKATLYALIDDVERVFFQKINDYIE
||.|.||| ..||..||.||..||.. . ..|||||.|||||...|||.|.......... | ..|.|..|......||| |...|.|...
svsnrrys.........kedhevedkvflfktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesiddala
EKNDIQSTLPKGLNSYQASLLYPDKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQ
||.|.||.||.|..||... .||.||.||||.|.|..||||||.|..|||.|||||||||||..|.||..||..||||||..||||||.|||||||||||
ekddlqsqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrkesekvkqLsvdHttdNedEllRlkdLGldieq
IKRNGRLGSHENTRSIGDYNIKKGYKDVDILSSATGPPGIATPSISGPYPINDIEY-ILLMSDGVYKTLECLTDPPTSDVYPRLLQLIQKAEKSANLQDI
||||.||||.|||||||||..|||||||||||||.|.|.||.|.|.|.|||.||.| ..|||||||||||..|.|.||.|...||..|...||.|.|||.
ikrnkrlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatlqdv
AREVLQDIEALHKEAYYDSAmtdprSTVAVNCRKRDDMTLMVLHFS
|..|...... ||.||..|| |..||.|||||||||.||.|.
AqavvdkvkrkHkdaylssa.....seravicrkrddmtllvlkfe
|
|||||||||
0034914 | PP2C-like | 168-513 | 5.3e-39 | 126.9 | In-house | 9-290 (295) | alignment | ||
Range on Protein: 168-513
Range on HMM: 9-290/295.0
YSYNSVINCRYSITETSELSADPDHYNEDRVFFAK-----TDDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVglrFETKATLYALIDDVERVFFQ
... ... .... . ..|||.|.. ..|.....||||| | .|. .. ..|.. ... . . . . . | .. | |.
lellllsslllllrvgvasdqGrrksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekl...lllltlsledieealrkafl
KINDYIEEKNDIQstlpkglnsyqasllypdkinrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVyRKHfeKFRQLSVDHCVDNEDELERLKD
... .. |.. . . .|||||.|....| |||||||||||. . |.. ...||.||| ..||.| ||...
aadeellelallr..........................pelagsGtTavvalirgnklyvanvGDSravll.rng..elvqltvdhkpvnelererils
LGLDIEQikrNGRLGSHENTRSIGDYNIKKGYKDvdilsSATGPPGIATPSISgPYPI--NDIEYILLMSDGVYKTLEcltdppTSDVYPRLLQLIQkae
.| . . ..|. ||..||.. |. ... ...|. .|.| .. ... .| ...||.|||....|. .... . .|..
aggavsh...grvngvlavtRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls......neeivdivrslla...
KSANLQDIAREVLQD--IealhkeayydsamtdprstvavnCRKRDDMTLMVLHF
|. .|...|.|... . .||..| .|...
kgldleeaaeeLvdlAla.......................rgsrDNiTvvvvrl
|
|||||||||
PP2Cc_SM00332 | 192-510 | 4.6e-34 | 111.1 | In-house | 22-273 (274) | alignment | |||
Range on Protein: 192-510
Range on HMM: 22-273/274.0
HYNEDRVFFAKT----DDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVGL--RFETKATLYALIDDVERVFFQKINDYIEEKndiqstlpkglnsy
. .||... .|. ...||||| |.... .| ..|.. ... . .... |. . ... . .. . .|.
ksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..............
qasllypdkinrlqeiepeLAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHfekFRQLSVDHCVDNEDELERLKDLGLDIEQIkrnGRLGSHENTRSI
|.|||.|.. ...|||||||||||. . . ..|||||| ...|||..|.|. | .|. |. . .|..
...................alsGstavvallkkedlyvanvGDSravlcrngk...avqlsvdhkpedederkRikkaggvvekg...rvngglavsraf
GDYNIKKGYkdvdilsSATGPPGIATPSISGPYPINDIEYILLMSDGVYKtlecltdP----PTSDVYPRLLQLIqkaeksanlqdiA------------
||. || . . | .|.|... .. | ..|.|||.. |. .||. .
Gdhflkknk.......klkepyitaepdvkvvtltsedeflilaSDGlwd.......vlsnqevvdivrkllakg............ktndpqeaaelld
REVLQDiealhkeayydsamtdprstvavnCRKRDDMTLMV
.|.... ...|..| .|
eeairr........................ggseDniTvvv
|
|||||||||
PPM_PTC7 | 253-437 | 3e-32 | 105.1 | In-house | 45-221 (259) | alignment | |||
Range on Protein: 253-437
Range on HMM: 45-221/259.0
IDDVERVFFQKINDYIEEKNDIQST-LPKGLNSYQASLLYPDKINRLQEIE-PELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHC
.. ..... ..... ..|. . ... ... . . |. |. ....| .. .|.|||.|......|||||||||||. . .... ||..||
greaakyarehleeilkerksfeeleklekalrksflaldtdeelksseantepstsGstAvvalitgsklyvAnvGDSravLcrsgnav..kqltedHk
VDNEDELERLKDLGLDIEQIkRNGRLGSH-ENTRSIGDYNIKKGYKdvdilssaTGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
..|||| ||....| .... .|||. ...|..||. |.... . .. .|.| || .. |...|.|||.. .
psnedEreRiegaggsvsnv.gngrvngvlavsRafGdfelkpket........eeqlvsaePdisstkideedefliLasdGlwdvv
|
|||||||||
PP2C | Protein phosphatase 2C | 258-437 | 5.8e-29 | 94.4 | Pfam-A | 50-216 (255) | alignment | ||
Range on Protein: 258-437
Range on HMM: 50-216/255.0
RVFFQKINDYIEEKNDIQSTLpKGLNSYQASLLY-PDKINRLqEI--EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHCVDNE
... ..... ..|. . .. | . . | | |. ... .. . .. |.|||.|......|||||||||||. . ..... .|..|| ...|
kyarehleeilkeqksflele.kvekalrksfladtdeelks.skantepsksGstavvalirgkklyvAnvGDSravLcrkdnak..keltedHkpsde
DELERLKDLGLDIEQikrNGRLGSH-ENTRSIGDYNIKKGYkdvdilssatGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
|| ||....| ... |||. ...|..||. .|... .. .| | .. .. |...|.|||.. |
dEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvl
|
|||||||||
PP2C | Protein phosphatase 2C | 258-437 | 5.8e-29 | 94.4 | In-house | 50-216 (255) | alignment | ||
Range on Protein: 258-437
Range on HMM: 50-216/255.0
RVFFQKINDYIEEKNDIQSTLpKGLNSYQASLLY-PDKINRLqEI--EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEkfRQLSVDHCVDNE
... ..... ..|. . .. | . . | | |. ... .. . .. |.|||.|......|||||||||||. . ..... .|..|| ...|
kyarehleeilkeqksflele.kvekalrksfladtdeelks.skantepsksGstavvalirgkklyvAnvGDSravLcrkdnak..keltedHkpsde
DELERLKDLGLDIEQikrNGRLGSH-ENTRSIGDYNIKKGYkdvdilssatGPPGIATPSISGPYPINDIEYILLMSDGVYKTL
|| ||....| ... |||. ...|..||. .|... .. .| | .. .. |...|.|||.. |
dEreRIeeaggsvsn...ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvl
|
|||||||||
0049733 | PP2C-like | 191-513 | 2.8e-28 | 92.0 | In-house | 15-233 (235) | alignment | ||
Range on Protein: 191-513
Range on HMM: 15-233/235.0
DHYNEDRVFFaktdDVIVMAVFDGHDGNKASGLVEQYLFSKFINP--DvlvGLRFEtkatlyaliddvervffqkindyieE-----------------K
...|||.|.. .....||.||| | |.... ..|.. ... . | . .
rkvneDavlv....glllfavaDGhgghaagevasellvetllellle...lllld.........................leealrkaflaaneallel
ndiqstlpkglnsyqasllypdkinrLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfeKFRQLSVDHCVDNEDELERLKDLGLDIeqik
.. .. .|||||.|..... |||||||||||. . .. |..||..|| . ||.| .|....| .
..........................alaspelagmgtTavvalldggklyvanvGDsrayllrdg...klvqltedhspvnelerqriitaggav....
rnGRLGSHENTRSIGDYNIKkgykdvdilssatgppgiatPSISgPYPINDIEYILLMSDGVYKTlecltdpPTSDVYPRLL-QliqkaeksANLQDIAR
.|.. ||..||. .| | .. ..... ...||.|||... ... . .|| . .|...|.
..rvpgrlaltralGdlllk....................pdvt.vlelepgdflllasDGlwdv.......lsdeeivdllrs........ldleeaae
EVLQDIEAlhkeayydsamtdprstvavnCRKRDDMTLMVLHF
.... | .||..|..|...
rlvelala.....................rggrDNiTvvvvrl
|
|||||||||
subfamily_PPM1A_pd | Subfamily PPM1A | 174-474 | 7.4e-24 | 77.6 | In-house | 10-262 (282) | alignment | ||
Range on Protein: 174-474
Range on HMM: 10-262/282.0
INCRYSITETSELSADP-DHYNeDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINpdvlvglrfetkatlyaliddvervffqkiNDYIEEKN
.. ||.. ... .. |... . .... | |||||| |.... |.. | .. .. .. ..|..
nglrygvssmqgwrvemEDaht.vvaslgalkdwsfFavfDGHaGsevakyvkkhllenile..............................eeelkeaa
DIQSTLPKGLN-------------------------SyqasllypdkinrlqeiepelagGTTAVIAVVFNNNLYVANVGDSRAIAVyRKHfeKFRQLSV
.|. . .. | |.||| ..| ...|..||.|||||. . |. | |.
leasekdevkealrqgfLaldeairelstdlktadks.......................GsTavtvlvsekhliianlGDsRavlc.rng..kaaflte
DHCVDNEDELERLKDLGLDIEQIKRNGRLGsheNTRSIGDYNIKKGYKDVDILSSATgppgiATPSISGPYPINDIEYILLMSDGVYKTLeclTDpptSd
|| ....| .|... | . . || | .|..|||..|. . . | | . ... ....| .||.. .| .| .
DHkpsrpkEkkRieqAGGsvvvsRvnGaLA...vsRalGDyeykeeeekkaeeqlvs.....aepevtsierseeddflvlacDGiwDvl...sd...e.
vypRLLQLIQKA-EKSANLQDIAREVLQ
...|..| |.. .|. .|.....
...evvelvrkrlevadeleevakalvd
|
|||||||||
subfamily_PPM1G2_pd | Subfamily PPM1G2 | 201-438 | 4.4e-23 | 74.6 | In-house | 47-235 (287) | alignment | ||
Range on Protein: 201-438
Range on HMM: 47-235/287.0
AKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINpdvlvglrfetkatlyaliddvervffqkiN-DYIeeKNDIQSTLPKGLNSYQASLLYPdkinrlQ
.... ..|||||| |.|.. . . | .| . . .. .. .. | ... . .|| .
sddkslalfavfDGhGGakvakyagkklikkiak..............................kksfk..egaleqilkdafletDeellkd......e
EIEPELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHfekFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGShenTRSIGDYNIKKGYKDVDI
... | | |.|||.... ...|||||.|||||.. . . ..||.|| ..|.| .|... | .| . || | |..||.. ||. |
klkdesa.GstavvvlikeeklyvanaGDsravlsskgn...vkalsfDhkPqeesekkriiaagGfvelnrvngnLal...sralgDfefkknvkkkpe
LSSATGPPGIATPSISgpypiNDIEYILLMSDGVYKTLE
| | . . ... .| |...| ||.. |.
eqivtavPDvlvkkld.....eddeflvLaCDGiWDvlt
|
|||||||||
subfamily_PDP_pd | Subfamily PDP | 194-394 | 4.8e-17 | 55.1 | In-house | 11-244 (398) | alignment | ||
Range on Protein: 194-394
Range on HMM: 11-244/398.0
NEDRVFFAK--TDDVIVMAVFDGHDGNKASGLVEQYLFsKFINPDV-----LVGL--RFETKAT-----------LYALIDDVERVFFQKINDYIEEK--
.||| ..|| . . ....||||| |.... |.. |. |... . |. ..| ... | |. ....... ..|..|.
iEDrrseakllesngvlfgvfDGHggaacaeavskrLl.kyvaasllkkqvleeaekalesgkallkllkkskhkldvvsdeakklslselskylqelle
---NDIQSTLPKGLNSYQASL----LYPDKINRLQE-IEPElAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFE--KFRQLSVDHCVDNEDELERLK
......| |. .. . | | . |.| ... . |..|..|.. ...|.|||.||.||. ... . ..|| |...|||.|.||.|
aevekvkealkkaFlklDkdistealkklkekslreallva.lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRik
DLGLDIEQ--IKRNGR-LGSHENTRSIGDYNIKKGY
. |. . |||| ||. .| ||.. |
keHPgeesktvirngRlLgeLqPlRAFGdvryKwse
|
|||||||||
PPM_PTC7_SpoIIE | 249-513 | 4.4e-16 | 52.4 | In-house | 69-229 (230) | alignment | |||
Range on Protein: 249-513
Range on HMM: 69-229/230.0
LYALIDDVERVFFQKINDYieekndiqstlpkglnsyqasllypdkinrlqeiepELAGGTTAVIAVVFNNN--LYVANVGDSRAIAVYRKHFekfrqls
. ... . .. ......|. . .|.|||.|...... |||||.|||... | ..
peeilrrlnlalaadlede....................................psssgaTavvalidpstgklyvanaGdsppllvrddgg.......
vdhcvdnedELERLkDLGLDIEqI--KRNGRLGSHENTRSIGDYNIKKgykdvdilssatgppgiatpsisgpypindieyillmSDGVYktlECLTDPP
| ||. ..| .. . . |... ....||. .. .||| |. | .
.........ereri.vagglps.lGilpgrvfgvlavslapGdlllly.....................................tDGvv...eaepdts
TSDVYP--RLLQLIQKA--EKSAnLQDIAREVLQDIEALhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
. . ..|.|. .. .. .|.... |....|.. .. ...||.|| |...
dgelfgkdeflilasdglwdvls.pqelvdlvrdelekp...................aaeglleDDitllvvrv
|
|||||||||
subfamily_ILKAP_pd | Subfamily ILKAP | 299-465 | 4.5e-15 | 48.5 | In-house | 105-252 (293) | alignment | ||
Range on Protein: 299-465
Range on HMM: 105-252/293.0
QEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEK---FRQLSVDHCVDNEDELERLKDLGLDIeqikRNGR-LGSHENTRSIGDYNikkgY
.. .| |.||.. .| .| |||||.|||.|. | .|. . . .|..|| ...| .|.. | . |.|| || | .||||| . .
skakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvv....rdgrvlGvlevsrsiGdgr....f
KDVDIlssatgppgIATPSISGPYPINDIEYILLMSDGVYKTLEcltdppTSDVYPRLLQLIQKAEKSANL
| . . |.|| .. .. ...| ||..|... ...| |......|.. ..
krlGv.........istPdvkkceLtendlfvvlaCdGLwkvfs......adevvkfilkvledeeddrki
|
|||||||||
subfamily_PPM1G_pd | Subfamily PPM1G | 302-437 | 2.6e-14 | 46.1 | In-house | 291-416 (473) | alignment | ||
Range on Protein: 302-437
Range on HMM: 291-416/473.0
EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRkhfEKFRQLSVDHCVDNEDELERLKDLGLDIEqikRNGRL-GSHENTRSIGDYNIKKGyKDVDIL
|| |||||.|.. ...|.|||.||||.. | .||.|| ..| ||||.. | .. .||. | | .||.. || ....
epGedsGttAvvaLlkekklivAnaGDsRcvlsrn...GkAldlslDHkPeDevEleRiekAGGkvd...edgRvnGGLnlsRAlGDhaYkkn.eeLplk
SSAtgppGIATPSISGPYPINDIEYILLMSDGVYKTL
| | | .. |.. | .||.. ..
eqm....isAlPDikvltlteedeFlvlAcDGiWnvm
|
|||||||||
subfamily_PPM1E_pd | Subfamily PPM1E | 283-392 | 5.1e-14 | 45.1 | In-house | 78-184 (265) | alignment | ||
Range on Protein: 283-392
Range on HMM: 78-184/265.0
NSYQASLLYPDKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfeKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGSHENT
. . .. |. . .. .| .|.|||.... ...|||| .|||.|. | ...|| | ..||| .|....| . .| |. .
ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkg...eavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvs
RSIGDYNIKK
|.|||.. |.
RaiGDvklkp
|
|||||||||
subfamily_PPM1H_pd | Subfamily PPM1H | 201-364 | 2.1e-13 | 42.8 | In-house | 57-214 (404) | alignment | ||
Range on Protein: 201-364
Range on HMM: 57-214/404.0
AKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFIN--PDVLVGLRFETKaTLYALIDDVERVFFQKINDYIEEKNDIQSTLPKGlnSYQASLLYPDKINRL
... .. . ..|||| |. |. . . | .. . ||| | . . . ..... .. .. |||. . .| .| . . | |. .
eeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksa.eeeenteesskespssvseiyeekeiskeeLviG..alesaflemDeqiar
QEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVyrkHFEKFRQLSVDHCVdnEDELERLKDLG
.. . ...|| ||..|.|... ||||| |||||| | . .. ..|| |. | | .||. |.
ereayrikGGCtalvalvllgklYvanaGDsRailv...rkdeiiplsadftP..eteRqRlqela
|
|||||||||
subfamily_PPM1L_pd | Subfamily PPM1L | 206-393 | 7.6e-13 | 41.3 | In-house | 35-190 (269) | alignment | ||
Range on Protein: 206-393
Range on HMM: 35-190/269.0
VIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLVglrfetkatlyaliddvervffqkindyieeKNDIQSTLPKGLNS-YQASLLYPD-KINRLQEIEP
..|||||| |. |. ... | . | . . ..| . |.| . . .| | |. . .
esffavfdGhGGefaaefakdvlvkaiknkliel...............................dadkentepinfsklltdeilsvdekllekakrae
ELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYRKhfEKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRLGSHENTRSIGDYNIKKG
..| ||||.||.| ...| |||||||| . . .. | || || . | |.|. | | | .|..||| .|.
dia.GttalialvqesdlivanvGdsrGvlydkr..GkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdk
|
|||||||||
subfamily_PPM1D_pd | Subfamily PPM1D | 202-369 | 2.2e-12 | 39.7 | In-house | 31-173 (309) | alignment | ||
Range on Protein: 202-369
Range on HMM: 31-173/309.0
KTDDVIVMAVFDGHDGNKASGLVEQYLFSKFINPDVLvglrfetkatlyaliddvervffqkindYIEEKNDIQSTLPKGLNSYQASLLYPDKINRLQEI
.. .| ..|||||| |..|. . . |.|. . . . . .|..|... . .. . . .. . ..
eelevafvavfDGHGGkeAakfarehlwsvikkqkkf............................lssepedvleAireaflatheamkkkleeWpktks
EPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKH---FEKFRQLSVDHCVDNEDELERLKDLGLDIEQ
|||| . .. ...||||.||||... .... . . ..| .|| .. .| ||...|| .. .
gllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaa
|
|||||||||
subfamily_PPM1K_pd | Subfamily PPM1K | 260-392 | 7.8e-12 | 37.9 | In-house | 53-183 (263) | alignment | ||
Range on Protein: 260-392
Range on HMM: 53-183/263.0
FFQKINDYIEEKNDIQSTLPKGLNSYQASLLYPDKINrLQEIePELAGGTTAVIAVVFN-NNLYVANVGDSRAIAVyRKhfEKFRQLSVDHCVDNEDELE
. . .... |. .|.. | . .. . | . . . | .|. |||| .... . ..| .|..|||||| |. | ..|. || . |.| |
lekilkrllekekdleivlknafeeldkklkrylefs.vaea.ellssGttatvsllrdGtelvlaslGdsrailc.rn..GkakkltrdhdPeleeeke
RLKDLGLDIE-----QIKRNGRLgshENTRSIGDYNIKK
|.| | .| . . |||| |||.|| ..|.
rikaagGsvewnslgkplvngrl...amtrslGdldlkr
|
|||||||||
subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 305-389 | 4.3e-11 | 35.6 | In-house | 93-176 (255) | alignment | ||
Range on Protein: 305-389
Range on HMM: 93-176/255.0
LAGGTTAVIAVVFNNNLYVANVGDSRAIAVYRKHFEKfrQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRL-GSHENTRSIGDYN
||||. ... .. |.|||||||.. .. | .||.|| .|.| .|...|| . . . |. | .|..||
kfiGttaasvliiedkvyianvGdsrvvlcqkdgtak..rlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsf
|
|||||||||
subfamily_KAPP-like_pd | Subfamily KAPP-like | 256-436 | 1.7e-10 | 33.4 | In-house | 52-218 (266) | alignment | ||
Range on Protein: 256-436
Range on HMM: 52-218/266.0
VERVFFQKINDYIEEkndiQSTLPKGLNSYQASLLYPDKINRLQE-IEPELAGGTTAVIAVVFNN----NLYVANVGDSRAIAVYRKhfEKfRQLSVDHC
...| ......... | | |. | |. . .. ... .. |.|| .|.|... | ||||||| |. . | .|| ||
akklfpkelekllks....tkqddGGdniydqskllenafkevdaklkdfeyeGatatlalvwsdGqqrylqvanvGdssaflsrGn..es.lelskdhk
VDNEDELERLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKKgyKDVDIlssatgppgIATPSISGPYPINDI-EYILLMSDGVYKT
....| |.|| |. . . . |. .|..||. ||. ... . |..| .| .. . ..... |||..
akdpeekqrikddGitlsd..nqtrinGlavsralGdhfike..lniGl.........isepyvsnrilltpfdkflivasdGlwdv
|
|||||||||
PP2C_SIG_SM00331 | 195-512 | 5.9e-09 | 28.8 | In-house | 18-216 (217) | alignment | |||
Range on Protein: 195-512
Range on HMM: 18-216/217.0
EDRVFFAKTDD-VIVMAVFDGHDGNKASGLVEQYLFS---KFINPDvlvglrfetkatlyalidDVERVFFQKINDYIEEKndiqstlpkglnsyqasll
.| ... |... ....|.||... .|.... | . .... . . .....|..|.|.
GDyydvvklnegrlllvvaDgmGkGlaAaaassqlrtalrellseg..................eelsqalkrlnraiyee...................
ypdkinrlqeiEPELAGGTTAVIAVV--FNNNLYVANVGDSRAIAVYrkhfE--KFRQLSVdhcvdnedelerlkdlgldieqikrngrlgshentrsig
. | ...|...|.. ...|..||.|||| . . . . .|.
...........keekgmfaTlllalydfssgklsyanaGdsrpyllr....dgklveilkd.......................................
dynikkgykdvdILSSATGPPGIATPSISGpYPINDIEYILLMSDGVYKTLECLTdpptsdVYPRLLQLIQKAEKSANLQDIAREVLQDIEALHKEAYYd
... ..| .. |. .. . .||..||. . . . |..| .. . .|..|.. ......| |.. .
............vegaplGlepevsvdire.lelekgdllllytDGltearsekg......faeerleeiledlvdseaqelaqkiveellelakgsng.
samtdprstvavncrkRDDMTLMVLH
.||.|..|.
................eDdiTvvvvk
|
|||||||||
subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 301-371 | 1.1e-08 | 27.9 | In-house | 79-152 (292) | alignment | ||
Range on Protein: 301-371
Range on HMM: 79-152/292.0
IEPELAGGTTAVIAVVFNN-NLYVANVGDSRAIaVYR---KHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQIK
|. . ..|..| |.| .. .|..||||||||. ..| . . || || .. || .|.. | .| .
idaresattavvcarvrddralilanvGdsral.lgrclggsdyeliPlsrdhkPedPderarilraGGrveptr
|
|||||||||
subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 256-436 | 1.6e-08 | 26.7 | In-house | 51-228 (276) | alignment | ||
Range on Protein: 256-436
Range on HMM: 51-228/276.0
VERVFFQKINDYIEEKN-DIQSTLPKGLNSYQASLLYPDKINRLQ-EIEPELAGGTTAVIAVVFNNN----------LYVANVGDSRAIAVYRKhfEKfR
...| .... ... | . | | |. | |. | .. .. ... |.|| .|.|... | ||||||| |. . |
akklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdfeyeGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGn..es.l
QLSVDHCVDNEDELERLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKKgyKDVDIlssatgppgIATPSISGPYPINDI-EYILLMSDGVYKT
.|| || .. .| .|.|| |. . . . |. .|..||. ||. ... . |..| .| .. . ..... |||..
elskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfike..lniGl.........isepyvsnrilltpfdkflivasdGlwdv
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 194-465 | 1.7e-08 | 27.0 | Pfam-A | 12-207 (212) | alignment | ||
Range on Protein: 194-465
Range on HMM: 12-207/212.0
NEDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFiNPDVLVGLRFETKATLYALIDDVERVFFQKINdyieekndiqstlpkglnsyqasllypD
..|.... ...|. ..|| ||. | | ... . . . | | ... ||....|. .... .
cqDalaireasdgwllaVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvk...........................l
KINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAiaVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQikrngrlgshentrsigdynikkg
| .. .. |. . .|| ..||. .........||... |.|.. ....|. .. . . |. .|.. |
kqeaeaqqeelkdyatTlllavitpgeivffqiGDgai..vvrdrdgevqllgepdsgeyanettfltsedaeeel........................
ykdvdilssatgppgiatpsISGPYPINDIEYILLMSDGVYKTLecLTDPPTSDVYPRLLQLIQKAEKSANL
. .... .|||.||| . | ...| ... .||. ..... ...|
....................rirrlklepgdalllmTDGvsdsl..rkeepfrellaelletleeegaaeeL
|
|||||||||
PP2C_2 | Protein phosphatase 2C | 194-465 | 1.7e-08 | 27.0 | In-house | 12-207 (212) | alignment | ||
Range on Protein: 194-465
Range on HMM: 12-207/212.0
NEDRVFFAKTDDVIVMAVFDGHDGNKASGLVEQYLFSKFiNPDVLVGLRFETKATLYALIDDVERVFFQKINdyieekndiqstlpkglnsyqasllypD
..|.... ...|. ..|| ||. | | ... . . . | | ... ||....|. .... .
cqDalaireasdgwllaVADGaGsakrSdkGarlaveaa.gealeklleeeseqeeeallrqieneilasvk...........................l
KINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAiaVYRKHFEKFRQLSVDHCVDNEDELERLKDLGLDIEQikrngrlgshentrsigdynikkg
| .. .. |. . .|| ..||. .........||... |.|.. ....|. .. . . |. .|.. |
kqeaeaqqeelkdyatTlllavitpgeivffqiGDgai..vvrdrdgevqllgepdsgeyanettfltsedaeeel........................
ykdvdilssatgppgiatpsISGPYPINDIEYILLMSDGVYKTLecLTDPPTSDVYPRLLQLIQKAEKSANL
. .... .|||.||| . | ...| ... .||. ..... ...|
....................rirrlklepgdalllmTDGvsdsl..rkeepfrellaelletleeegaaeeL
|
|||||||||
PPM_PTC7_SpoIIE_motif | 425-513 | 3.9e-08 | 26.9 | In-house | 14-80 (81) | alignment | |||
Range on Protein: 425-513
Range on HMM: 14-80/81.0
YILLMSDGVYktlECLtdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
.||..||.. |. .|| .||.|...| .. .||..|......... |. ...||.||.||..
vllLyTDGlt...Ear....dsdgelfgkeellrladra.egkslqeladklvdevle....................ngsgereDDitllvlrv
|
|||||||||
SpoIIE | Stage II sporulation protein E (SpoIIE) | 424-513 | 5.7e-07 | 21.5 | Pfam-A | 125-192 (193) | alignment | ||
Range on Protein: 424-513
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLecltdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
. .||..|||. . ..| |||.|...| ....|............ .. ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv
|
|||||||||
SpoIIE | Stage II sporulation protein E (SpoIIE) | 424-513 | 5.7e-07 | 21.5 | In-house | 125-192 (193) | alignment | ||
Range on Protein: 424-513
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLecltdppTSDVYP----RLLQLIQKAeKSANLQDIAREVLQDIEAlhkeayydsamtdprstvavNC--RKRDDMTLMVLHF
. .||..|||. . ..| |||.|...| ....|............ .. ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv
|
|||||||||
subfamily_PP2D1_pd | Subfamily PP2D1 | 318-388 | 5.1e-06 | 18.5 | In-house | 187-255 (492) | alignment | ||
Range on Protein: 318-388
Range on HMM: 187-255/492.0
NNNLYVANVGDSRAIAVyRKhfEKFRQLSVDHCVDNEDELERLKDLGLDIEQIKRNGRL-GSHENTRSIGDY
||.||.|. .|. . |. | .| .| |. | .|.. | . . ..||. | ..|| .| |
lgvlyianaGnvqAvLc.re..GkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny
|