Gene TAB1-2 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily TAB1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP216_AA protein Get Run
AqueP216_AA_36-362 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TAB1_pd Subfamily TAB1 20-362 1.4e-151 497.0 In-house 2-331 (333) alignment
Range on Protein: 20-362
Range on HMM: 2-331/333.0
IENARYSieaeskvmssFPDHTNEDKCFILtprSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSRFINPDVLDEL-KANPMETLNQLILETEKKFFREIRN
..| |||           .||..|||.|..   .|..|||..|||||.||.|.....| .|..........||| .|...|.|.... |.|.||...|..
vsnrrys..........kedhevedkvflf...ktendpilyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverkflesidd

FVEEKDDILGTLPKGVTSYEAYILYPEKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVY---KDQHKQLSVDHGVDNEDELKRLKDLGLD
...||||.  .||.||.|||.. .|||||.||||.|.|..||||||.|..|||.|||||||||||..|.   ....||||||| .||||||.||||||||
alaekddlqsqlPegvssyeleeqypekierlqeleeeisgGttAvvalifnnkLyVaNvGdsrAllvkrkesekvkqLsvdHttdNedEllRlkdLGld

IEQIKRNGRLGSHENTRSIGDYNIKIGYKDVDVLSSATGPPGIAIPSINGPYPINDIEY-ILLMSDGVYKTLEYLTDPPTSDVYPRLLQLIQEAEKSVDL
|||||||.||||.|||||||||..|.||||||.||||.|.|.|| |.|.|.|||.||.| ..|||||||||||..|.|.||.|...||..|.|.||...|
ieqikrnkrlgskentRsiGdykvkkgykdvdilssakgePviaePdiqgaypiddityflvlmSdGvyktLeevtgpetsnvenillevitelekqatl

QDIANKVLQDIKISHEVVYYDSAmtdprSTVAVNCRKRDDMTLIVLKF
||.|..|....|..|. .|..||     |..||.|||||||||.||||
qdvAqavvdkvkrkHkdaylssa.....seravicrkrddmtllvlkf

0034914 PP2C-like 37-362 1.5e-40 132.0 In-house 31-290 (295) alignment
Range on Protein: 37-362
Range on HMM: 31-290/295.0
FpDHTNEDKCFILTPRST-QDDPIIMAVFDGHDGSKGSTLAEGMLYSRFIN-----PDVLDELKANPMETLNQLILETEKKFFREIRNFveekddilgtl
   ..||| ......  . ..| ....||||| |.. . .|  .|.. ...        |..   ...| | . .|.............           
r.rksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallr...........

pkgvtsyeayilypekinrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQikrNGRLGSHEN
                          . .|||||.|....| |||||||||||. . .....||.||| ..||.| .|....|  .     . ..|.   
.......................pelagsGtTavvalirgnklyvanvGDSravllrngelvqltvdhkpvnelererilsaggavsh...grvngvlav

TRSIGDYNIKIGYKDvdvlsSATGPPGIAIPSINgPYPI--NDIEYILLMSDGVYKTLEyltdppTSDVYPRLLQLIQeaeKSVDLQDIAN-------Kv
||..||.. |. ...      ...|. .|.| .   ...  .| ...||.|||....|.       ....  . .|..   |. ||...|.       . 
tRalGdfdlklllsl.....llleplvsaePdvt.vleltledddfllLasDGlwdvls......neeivdivrslla...kgldleeaaeeLvdlAla.

lqdikishevvyydsamtdprstvavnCRKRDDMTLIVLKF
                           . .||..| .|...
...........................rgsrDNiTvvvvrl

PP2Cc_SM00332 40-359 2e-35 115.5 In-house 22-273 (274) alignment
Range on Protein: 40-359
Range on HMM: 22-273/274.0
HTNEDKCFILTPRSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSRFINPDV--LDELKANPMETLNQLILETEKKFFREIRNFVEEKddilgtlpkgvtsy
...|| ... .  . ..|  ...||||| ||. . ..   |.. ...     .|||. .. | |.. .|.|....  | ..  .|.              
ksmeDahvvvvdlveeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen..............

eayilypekinrlqeiepeLAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIkrnGRLGSHENTRSIGDY
                      |.|||.|.. ...|||||||||||. . .....|||||| ...|||.||.|. |  .|.       |. . .|..||.
...................alsGstavvallkkedlyvanvGDSravlcrngkavqlsvdhkpedederkRikkaggvvekg...rvngglavsrafGdh

NIK--IgykdvdvlsSATGPPGIAIPSINGPYPINDIEYILLMSDGVYKtleyltdPPTSDVYPRLLQLIQEAEKSVDLQDIANKVLQ----Dikishev
  |  .         . . |  .| |...     .. | ..|.|||..         ....    ... . . .|  | |..|... .    .       
flkknk.........klkepyitaepdvkvvtltsedeflilaSDGlwd.......vlsnqevvdivrkllakgktndpqeaaelldeeairr.......

vyydsamtdprstvavnCRKRDDMTLIV
                  ...|..| .|
.................ggseDniTvvv

PPM_PTC7 114-288 2.7e-32 105.2 In-house 54-223 (259) alignment
Range on Protein: 114-288
Range on HMM: 54-223/259.0
REIRNFVEEKDDILGT-LPKGVTsYEAYIL-YPEKI------NrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHK-QLSVDHGVDNED
  . ....|. .   . ... .  ....   . ..       |     . .. .|.|||.|......|||||||||||. . ... . ||..|| ..|||
ehleeilkerksfeeleklekal.rksflaldtdeelkssean.....tepstsGstAvvalitgsklyvAnvGDSravLcrsgnavkqltedHkpsned

ELKRLKDLGLDIEQIkRNGRLGSH-ENTRSIGDYNIKIGYKdvdvlssaTGPPGIAIPSINGPYPINDIEYILLMSDGVYKTLEY
| .|....|  .... .|||.    ...|..||.  |....        . .. .| | |.     .. |...|.|||..  ...
EreRiegaggsvsnv.gngrvngvlavsRafGdfelkpket........eeqlvsaePdisstkideedefliLasdGlwdvvsd

PP2C Protein phosphatase 2C 40-288 1.1e-30 100.1 Pfam-A 13-218 (255) alignment
Range on Protein: 40-288
Range on HMM: 13-218/255.0
HTNEDKCFILTPR---STQDDPIIMAVFDGHDGSKGSTLAEGMLYsrfinpDVLDELKANPMETlnqliletekkffreirnfveekdDILG--------
...||....| .    | ...  ..|||||| |.. ...|. .|       ..|.| |  .  .                        .           
ksmedahialknlekssgkssvaffavfdghggreaakyarehle......eilkeqksflele........................kvekalrksfla

-------TlpkgvtsyeayilypeK-INrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHK-QLSVDHGVDNEDELKRLKDLGLDIEQi
       .                .  |     . ..  |.|||.|......|||||||||||. . ||. | .|..|| ...||| .|....|  ... 
dtdeelks................skan.....tepsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.

krNGRLGSH-ENTRSIGDYNIKIGYkdvdvlssatGPPGIAIPSINGPYPINDIEYILLMSDGVYKTLEY
  |||.    ...|..||. .| ..           .. .| | ..     .. |...|.|||..  |..
..ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvlsd

PP2C Protein phosphatase 2C 40-288 1.1e-30 100.1 In-house 13-218 (255) alignment
Range on Protein: 40-288
Range on HMM: 13-218/255.0
HTNEDKCFILTPR---STQDDPIIMAVFDGHDGSKGSTLAEGMLYsrfinpDVLDELKANPMETlnqliletekkffreirnfveekdDILG--------
...||....| .    | ...  ..|||||| |.. ...|. .|       ..|.| |  .  .                        .           
ksmedahialknlekssgkssvaffavfdghggreaakyarehle......eilkeqksflele........................kvekalrksfla

-------TlpkgvtsyeayilypeK-INrlqeiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHK-QLSVDHGVDNEDELKRLKDLGLDIEQi
       .                .  |     . ..  |.|||.|......|||||||||||. . ||. | .|..|| ...||| .|....|  ... 
dtdeelks................skan.....tepsksGstavvalirgkklyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.

krNGRLGSH-ENTRSIGDYNIKIGYkdvdvlssatGPPGIAIPSINGPYPINDIEYILLMSDGVYKTLEY
  |||.    ...|..||. .| ..           .. .| | ..     .. |...|.|||..  |..
..ngrvngsLavsRalGdfelkpke..........eqlvsaePdvtsvklteedefliLasdGlwdvlsd

0049733 PP2C-like 38-362 1.2e-30 99.7 In-house 14-233 (235) alignment
Range on Protein: 38-362
Range on HMM: 14-233/235.0
PDHTNEDKCFIltprstqdDPIIMAVFDGHDGSKGSTLAEGMLYSRFINPdVLDELKANPMETLNQLILETEKKFFREirnfveekddilgtlpkgvtsy
 ...||| ...        . ...||.||| |. .. .| ..|.. ...  .|. |  ...| | . .|.... ....                      
vrkvneDavlv........glllfavaDGhgghaagevasellvetllel.llelllldleealrkaflaaneallel......................

eayilypekinrLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIeqikrnGRLGSHENTRSIGDY
             .. ..   .|||||.|..... |||||||||||. . ...  ||..|| . ||.| .|....|  .        .|..  ||..||.
............alaspelagmgtTavvalldggklyvanvGDsrayllrdgklvqltedhspvnelerqriitaggav......rvpgrlaltralGdl

NIKigykdvdvlssatgppgiaiPSINgPYPINDIEYILLMSDGVYKTleyL---------TDPPTSDVYPRLLQLIQEaeksvdlqdiankvlqdikis
 .|                    | .   ..... ...||.|||...    |         .. . ...  ||..|  .                     
llk....................pdvt.vlelepgdflllasDGlwdv...lsdeeivdllrsldleeaaerlvelala.....................

hevvyydsamtdprstvavnCRKRDDMTLIVLKF
                      .||..|..|...
....................rggrDNiTvvvvrl

subfamily_PPM1A_pd Subfamily PPM1A 40-287 1.7e-24 79.6 In-house 24-235 (282) alignment
Range on Protein: 40-287
Range on HMM: 24-235/282.0
HTNEDKCFILTPRSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSRFINPDVLDE--LKANPMETLNQLILETEKKFFREIRNFVEEKDD---Ilgtlpkgv
 ..||.  . .  ... |    |||||| ||. .. .. .| .  .. . | |  |.|.. ..... . .   ..  .||.  ....             
vemEDahtvvaslgalkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlktadks........

tsyeayilypekinrlqeiepelagGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRLGsheNTRSI
                         |.||| ..| ...|..||.|||||. . . . . |. ||  ....| ||... |  .   . || |     .|..
.........................GsTavtvlvsekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkRieqAGGsvvvsRvnGaLA...vsRal

GDYNIKIGYKDVDVLSSATGPPGIAIPSIngpypINDIEYILLMSDGVYKTLE
|||..|   .        .. | ... ..     ... ....| .||.. .|.
GDyeykeeeekkaeeqlvsaepevtsier.....seeddflvlacDGiwDvls

subfamily_PPM1G2_pd Subfamily PPM1G2 52-286 4e-24 78.0 In-house 46-234 (287) alignment
Range on Protein: 52-286
Range on HMM: 46-234/287.0
RSTQDDPIIMAVFDGHDGSKGSTLAEGMlysrfinpdvldelkanpmetL-----NqliletekkffreirnfveeKDDIL-GTLPKGVtsYEAYILYPE
.| ...  ..|||||| |.| .  |                        |     .                    |..   |.| . .   .|..   |
ksddkslalfavfDGhGGakvakyagkk.....................likkiak....................kksfkegaleqil..kdafletDe

KINRLQEIEPELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRLGShenTRSIGDYNIKIGYKD
.. . .... | | |.|||.... ...|||||.|||||..  | . |.||.||  ..|.| ||... |  .|  . || |      |..||.. | . | 
ellkdeklkdesa.GstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLal...sralgDfefkknvkk

VDVLSSATGPPGIAIPSINgpypiNDIEYILLMSDGVYKTL
       |  | . . ...     .| |...|  ||..  |
kpeeqivtavPDvlvkkld.....eddeflvLaCDGiWDvl

PPM_PTC7_SpoIIE 40-361 1.1e-19 64.1 In-house 13-228 (230) alignment
Range on Protein: 40-361
Range on HMM: 13-228/230.0
HTNEDKCFILTPR---STQDDPIIMAVFDGHDGSKgsTLAEGMLYsrfinpDVLDELKANPMETLNQLILETEKKFFREIRNFveekddilgtlpkgvts
...||..... .    | ..  .. ...||| |.   .|| |.|       ..|.||. . .|...... ... .........                 
ksmedahispansekssggrlalvvgdvdGhGgra..alamgllr......talrelafaglekpeeilrrlnlalaadlede.................

yeayilypekinrlqeiepELAGGTTAVIAVVFNNN--LYVANVGDSRAIAVYKDQHkqlsvdhgvdnedELKRLkDLGLDIEqI--KRNGRLGSHENTR
                   .  .|.|||.|......  |||||.|||... | .|..             | .|. ..|  .. .    .   |... ..
...................psssgaTavvalidpstgklyvanaGdsppllvrddgg.............ereri.vagglps.lGilpgrvfgvlavsl

SIGDYNIKIgykdvdvlssatgppgiaipsingpypindieyillmSDGVYKTLEYltdPPTSDVYP--RLLQLIQEA-EKSVDLQDIANKVLQDIKISh
..||. ..                                      .|||     .    ..   .   ..|.|. ..    ...|... .|.....   
apGdlllly.....................................tDGvveaepd...tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp.

evvyydsamtdprstvavNC--RKRDDMTLIVLK
                  ..  ...||.||.|..
..................aaeglleDDitllvvr

subfamily_PPM1H_pd Subfamily PPM1H 42-213 2.6e-18 59.0 In-house 42-214 (404) alignment
Range on Protein: 42-213
Range on HMM: 42-214/404.0
NEDKCFILTPRSTQD----DPIIMAVFDGHDGSKGSTLAEGMLYSRFIN--PDVLDELKANPMETLNQLILETeKKFFREIRNFVEEKDDILGTLPKGVT
...|    .|....     .  . ..|||| ||  ...|  .| ..  .   |||. |...  |. ..   .. |.     .. .|||.    .| .|  
kkeksvtskpkekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeeeenteess.kespssvseiyeekeiskeeLviGal

SyEAYILYPEKINRLQEiEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVdnEDELKRLKDLG
  .|..   |.|.| .| . ...|| ||..|.|... ||||| |||||| | ||. ..|| |.    | | .||. |.
e.saflemDeqiarere.ayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftP..eteRqRlqela

subfamily_PPM1G_pd Subfamily PPM1G 157-286 5.2e-16 51.7 In-house 294-416 (473) alignment
Range on Protein: 157-286
Range on HMM: 294-416/473.0
LAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEqikRNGRL-GSHENTRSIGDYNikigYKDVDVLSSATGP
   |||||.|.. ...|.|||.||||..   . .  .||.||  ..| ||.|..  |  ..    .||. |     | .||..    ||    |      
edsGttAvvaLlkekklivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiekAGGkvd...edgRvnGGLnlsRAlGDha....YkkneeLplkeqm

pGIAIPSINGPYPINDIEYILLMSDGVYKTL
   |.| |.     .. |.. | .||.. ..
.isAlPDikvltlteedeFlvlAcDGiWnvm

subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 41-237 9.4e-16 50.8 In-house 19-175 (255) alignment
Range on Protein: 41-237
Range on HMM: 19-175/255.0
TNEDKCFILTPRSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSrfINPDVLDELKANPMETLNQLILETEKKFfreirnfveekddilgtlpkgvtsyeay
| ||.  |      ..|  ..|.|||| |.. .. |   ||   |  ..||  .|||...|..   |.. ..                            
tmedelviyGsfrdksdedyyalfdGhgGraaakfaseelyk..ilaelldlnnanPvkslkkaykeistqi............................

ilypekinrlqEIEPeLAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQ-HKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRL-GSHENTRSIGDY
           .  |    ||||. ... ..  |.|||||||..   ||   |.||.||   .|.| ||...||  . . .   |. |    .|..|| 
...........serp.kfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds

subfamily_PPM1E_pd Subfamily PPM1E 156-240 2.9e-15 49.1 In-house 99-183 (265) alignment
Range on Protein: 156-240
Range on HMM: 99-183/265.0
ELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRLGSHENTRSIGDYNIK
.| .|.|||.... ...|||| .|||.|. | | .  ||   |  ..||| ||....|  . .|      |.   .|.|||.. |
klksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk

subfamily_ILKAP_pd Subfamily ILKAP 153-316 7.3e-15 47.9 In-house 107-254 (293) alignment
Range on Protein: 153-316
Range on HMM: 107-254/293.0
IEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQHKQ------LSVDHGVDNEDELKRLKDLGLDIeqikRNGR-LGSHENTRSIGDYNikigYKD
 .|    |.||.. .| .| |||||.|||.|. | |... .      |..||   ...| ||..  |  .    |.|| ||  | .||||| .    .| 
akPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvv....rdgrvlGvlevsrsiGdgr....fkr

VDVLSSatgpPGIAIPSINGpypiNDiEYILLMSDGVYKTLEyltdppTSDVYPRLLQLIQEAEKSVDLQD
. | |     | .    ..     ||  ...|  ||..|...      ...|    |......|.. ....
lGvist....PdvkkceLte....nd.lfvvlaCdGLwkvfs......adevvkfilkvledeeddrkike

subfamily_PDP_pd Subfamily PDP 158-251 1.5e-14 47.0 In-house 151-253 (398) alignment
Range on Protein: 158-251
Range on HMM: 151-253/398.0
AGGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQH-----KQLSVDHGVDNEDELKRLKDLGLDIEQ--IKRNGR-LGSHENTRSIGDYNIKIGYK-DVDV
. |..|..|.. ...|.|||.||.||.   ....     ..|| |. .|||.|..|.|    . |.  . |||| ||.   .|  ||.. |.  . .  |
lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelqkkv

LSS
|..
lek

subfamily_PPM1L_pd Subfamily PPM1L 42-240 1.9e-14 46.6 In-house 19-188 (269) alignment
Range on Protein: 42-240
Range on HMM: 19-188/269.0
NEDKCFILTPRSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSRFINpDvLDELKANPMETLNqliletekkffreirnfveekddilgtLPKGVTSYEAYI
 ||.  | .  . . .. ..|||||| |   .  |. .|     |   | ||.|.  .|.                            .  .    .  .
medrfeieediknktgesffavfdGhGGefaaefakdvlvkaikn.k.lieldadkentep...........................infsklltdeil

LYPEKINRLQEIEPELAgGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQ-HKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRLGSHENTRSIGDYNIK
   ||.    . . ..| ||||.||.| ...| |||||||| . . |.     || ||   .  | ||.|. |  |         |    .|..||| .|
svdekllekakraedia.GttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk





subfamily_PPM1K_pd Subfamily PPM1K 41-240 2.8e-14 45.9 In-house 17-182 (263) alignment
Range on Protein: 41-240
Range on HMM: 17-182/263.0
TNEDKCFILtprSTQDDPIIMAVFDGHDGSKGSTLAEGMLYSrFINpDVLdELKANPMETLNQLILETEKKFFREIRNFVEEKddilgtlpkgvtsyeay
 |||.  ..     ... . .|||||| ||     .   |    .. ..| |   .  . |..  .| .||. | ..  | |.                 
enedriklk...eldpellyvavfdGhaGsaaadfvhdklek.ilk.rll.ekekdleivlknafeeldkklkrylefsvaea.................

ilypekinrlqeiePELAGGTTAVIAVVFN-NNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIE-----QIKRNGRLgshENTRSI
               .|. |||| .... . ..| .|..||||||   . . |.|. ||  . |.| .|.|  |  .|     . . ||||     |||.
..............ellssGttatvsllrdGtelvlaslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrl...amtrsl

GDYNIK
|| ..|
Gdldlk

subfamily_KAPP-like_pd Subfamily KAPP-like 151-241 2.1e-10 33.1 In-house 88-184 (266) alignment
Range on Protein: 151-241
Range on HMM: 88-184/266.0
QEIEPEL----AGGTTAVIAVVFNN----NLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKI
.|.. .|      |.|| .|.|...     | ||||||| |.  . ..  .|| ||  ....| .|.|| |. . .   . |.     .|..||. || 
kevdaklkdfeyeGatatlalvwsdGqqrylqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsd..nqtrinGlavsralGdhfike

PP2C_2 Protein phosphatase 2C 42-306 1.6e-09 30.4 Pfam-A 12-199 (212) alignment
Range on Protein: 42-306
Range on HMM: 12-199/212.0
NEDKCFiltPRSTQDDPIImAVFDGHDGSKGSTLAegmlySRFINPDVLDELKANPmetlNQ----LiletEKKFFREIRNFVEE--Kddilgtlpkgvt
..|...    |...|  .. || ||.   |.|  .     .|.    ... |...     ..         |....|.|.| ...  |            
cqDala...ireasdgwll.aVADGaGsakrSdkG.....arlaveaagealekll....eeeseqe....eeallrqieneilasvk............

syeayilypEKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVY-KDQHKQLSVDHGVDNEDELKRLKDLGLDIEQikrngrlgshentrsi
          | .. .. |.  . .|| ..||. .........||......   .. ..|. ..  . . |. .|..     |                 
.........lkqeaeaqqeelkdyatTlllavitpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel................

gdynikigykdvdvlssatgppgiaipsI--NGPypINDIEYILLMSDGVYKTLeyLTDPPTSDVYPRLLQLIQ
                               ...   .... .|||.||| . |   ...|  ... .||. ..
............................rirrlk..lepgdalllmTDGvsdsl..rkeepfrellaelletle

PP2C_2 Protein phosphatase 2C 42-306 1.6e-09 30.4 In-house 12-199 (212) alignment
Range on Protein: 42-306
Range on HMM: 12-199/212.0
NEDKCFiltPRSTQDDPIImAVFDGHDGSKGSTLAegmlySRFINPDVLDELKANPmetlNQ----LiletEKKFFREIRNFVEE--Kddilgtlpkgvt
..|...    |...|  .. || ||.   |.|  .     .|.    ... |...     ..         |....|.|.| ...  |            
cqDala...ireasdgwll.aVADGaGsakrSdkG.....arlaveaagealekll....eeeseqe....eeallrqieneilasvk............

syeayilypEKINRLQEIEPELAGGTTAVIAVVFNNNLYVANVGDSRAIAVY-KDQHKQLSVDHGVDNEDELKRLKDLGLDIEQikrngrlgshentrsi
          | .. .. |.  . .|| ..||. .........||......   .. ..|. ..  . . |. .|..     |                 
.........lkqeaeaqqeelkdyatTlllavitpgeivffqiGDgaivvrdrdgevqllgepdsgeyanettfltsedaeeel................

gdynikigykdvdvlssatgppgiaipsI--NGPypINDIEYILLMSDGVYKTLeyLTDPPTSDVYPRLLQLIQ
                               ...   .... .|||.||| . |   ...|  ... .||. ..
............................rirrlk..lepgdalllmTDGvsdsl..rkeepfrellaelletle

subfamily_PPM1D_pd Subfamily PPM1D 159-218 2.4e-09 29.7 In-house 108-173 (309) alignment
Range on Protein: 159-218
Range on HMM: 108-173/309.0
GGTTAVIAVVFNNNLYVANVGDSRAIAVYKDQ------HKQLSVDHGVDNEDELKRLKDLGLDIEQ
 |||| . .. ...||||.||||...  .|..       |.| .||  .. .| .|...|| .. .
aGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaa

PP2C_SIG_SM00331 54-362 6e-09 28.8 In-house 26-217 (217) alignment
Range on Protein: 54-362
Range on HMM: 26-217/217.0
TQDDPIIMAVFDGHDGSKGSTLAegmlySRFINPDVLDELKANpmetlnqlilETEKKFFR--------Eirnfveekddilgtlpkgvtsyeayilype
.... ....|.||... . . .|     |. . . .  .|...          |. .....        |                              
lnegrlllvvaDgmGkGlaAaaa.....ssqlrtalrellseg..........eelsqalkrlnraiyee..............................

kinrlqeiEPELAGGTTAVIAVV--FNNNLYVANVGDSRAIAVYkDQHKQLSVDHgvdnedelkrlkdlgldieqikrngrlgshentrsigdynikigy
        . |  ...|...|..   ...|..||.|||| . .  |.. .  ...                                             
........keekgmfaTlllalydfssgklsyanaGdsrpyllr.dgklveilkd.............................................

K-----------DvdvlssatgppgiaIPSINGPYPINDIeyILLMSDGVYKTLEYLTdPPTSDVYPRLLQLIqeaekSVDLQD----IANKVLQDIKIS
.           .              . . .  .   |.  .||..||.    .  .   . ..   | .|      .  .|.    | ...|. .| |
vegaplGlepevs..............vdirelelekgdl..lllytDGltearsekg.faeerleeiledlv.....dseaqelaqkiveellelakgs

HEvvyydsamtdprstvavncrkRDDMTLIVLKF
.                      .||.|..|.|.
ng.....................eDdiTvvvvkv

subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 160-241 1e-08 27.4 In-house 105-194 (276) alignment
Range on Protein: 160-241
Range on HMM: 105-194/276.0
GTTAVIAVVFNNN----------LYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQikRNGRLGSHENTRSIGDYNIKI
|.|| .|.|...           | ||||||| |.  . ..  .|| ||  .. .| .|.|| |. . .   . |.     .|..||. || 
GatatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsd..nqtrinGlavsralGdhfike

subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 152-220 1.2e-08 27.9 In-house 78-152 (292) alignment
Range on Protein: 152-220
Range on HMM: 78-152/292.0
EIEPELAGGTTAVIAVVFNN-NLYVANVGDSRAIAVY-----KDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIK
 |.  . ..|..| |.| .. .|..||||||||.        . . . || ||  .. || .|..  |  .|  .
tidaresattavvcarvrddralilanvGdsrallgrclggsdyeliPlsrdhkPedPderarilraGGrveptr

PPM_PTC7_SpoIIE_motif 274-362 7.8e-08 25.9 In-house 14-80 (81) alignment
Range on Protein: 274-362
Range on HMM: 14-80/81.0
YILLMSDGVYktleyltDPPTSDVYP----RLLQLIQEAeKSVDLQDIANKVLQDIKIshevvyydsamtdprstvavNC--RKRDDMTLIVLKF
 .||..||..       . ..||       .||.|...| .. .||..| |......                     |.  ...||.||.||..
vllLyTDGlt.......Eardsdgelfgkeellrladra.egkslqeladklvdevle....................ngsgereDDitllvlrv

subfamily_PP2D1_pd Subfamily PP2D1 170-237 1.6e-07 23.4 In-house 187-255 (492) alignment
Range on Protein: 170-237
Range on HMM: 187-255/492.0
NNNLYVANVGDSRAIAVYKDQHKQLSVDHGVDNEDELKRLKDLGLDIEQIKRNGRL-GSHENTRSIGDY
   ||.||.|. .|. . . . ..|  .|   |. | .|..  |  . . ..||.  |  ..|| .| |
lgvlyianaGnvqAvLcreGkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGny

SpoIIE Stage II sporulation protein E (SpoIIE) 273-362 1.2e-06 20.4 Pfam-A 125-192 (193) alignment
Range on Protein: 273-362
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLeyltdppTSDVYP----RLLQLIQEAeKSVDLQDIANKVLQDIKIshevvyydsamtdprstvavNC--RKRDDMTLIVLKF
. .||..|||. .        ..|       |||.|..|| .. .|............                     ..  ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv

SpoIIE Stage II sporulation protein E (SpoIIE) 273-362 1.2e-06 20.4 In-house 125-192 (193) alignment
Range on Protein: 273-362
Range on HMM: 125-192/193.0
EYILLMSDGVYKTLeyltdppTSDVYP----RLLQLIQEAeKSVDLQDIANKVLQDIKIshevvyydsamtdprstvavNC--RKRDDMTLIVLKF
. .||..|||. .        ..|       |||.|..|| .. .|............                     ..  ...||.||.||..
dllllyTDGvtEar.......dpdgelfgkerllallaea.egesleelldalveelle....................lgsgeleDDitllvlrv

subfamily_PPM1E_pd Subfamily PPM1E 40-115 6e-06 18.6 In-house 16-94 (265) alignment
Range on Protein: 40-115
Range on HMM: 16-94/265.0
HTNEDKCFILTP-----R-STQDDPIIMAVFDGHDGSKGSTLAEGMLYSRFINPdvlDELKANPMETLNQLILETEKKFFRE
.. ||.. .|         . ...   .|||||| |.. .. |   |..  ..     .|| .|.| |.. . .|...| . 
rkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrq...eklkedpaealkeafkltDerflqk