Synonym: CELE_C25A6.1, C25A6.1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 5-285 | 4.7e-196 | 642.8 | In-house | 1-297 (297) | alignment | ||
Range on Protein: 5-285
Range on HMM: 1-297/297.0
VVDNIIIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLL
|||.||||||||||||||||.||||.||||||||||||||.||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
vvdsiiidvlsasthekllskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivll
LAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSP----------------SHDGKERLVADL
||||||||||||||||||||||||||||||||||||||||||..|||||||||||.||||.||||||||||| |..|||||||||
laykvkfpgnlfllrgnhecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegkerlvadl
LWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTSG
|||||||||||||||.||||||||||||||.||.|||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lwadpisglsgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrptsg
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 5-284 | 1.3e-147 | 483.6 | In-house | 2-295 (298) | alignment | ||
Range on Protein: 5-284
Range on HMM: 2-295/298.0
VVDNIIIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLL
.||...|.|||.|..|| |..||.| .| ||..|| ..||.|||.||..||||||||||||..||||||...|.||.||||||||||||||...|.||||
evdellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivll
LAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSP-------------SHDGKE-RLVADLLW
||||||.| |.||||||||||..|.||||||||..||.|.|....||||||.|||..||...|||||||||. ..|.|| .|..||||
laykvkypnnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllw
ADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
||| . ..|..||.||... ||.|.| ........||..||||||||||||||..|||||||||||||||||.||.|..||||..|||.|.|..
adpenavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpek
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 6-285 | 7.8e-116 | 379.5 | In-house | 3-296 (299) | alignment | ||
Range on Protein: 6-285
Range on HMM: 3-296/299.0
VDNIIIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLL
||... .|. || |.. . | . .| ..| .|| | |..|..|||.||||||||. ||||.|.. |.|| .|.||||||||||| .|.|.|||
vdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlll
AYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKE--------------RLVADLLWA
..|.|.| ..|.||||||| .|.||||||||.|||.| |....||| |...||.|||...|||||||||| . . | |||||
cfkikyperffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwa
DPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTSG
|| . ... | || ||.| | .|.| ...||..|||||||||||||| .||||||||||||||||| || | ||.| |.| .|.||.
dpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpk
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 26-284 | 3.3e-107 | 350.9 | In-house | 9-280 (282) | alignment | ||
Range on Protein: 26-284
Range on HMM: 9-280/282.0
VITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECE
..| . .||. | .....| ..|..||.|..||||||. ||||||...| ||..||||||||||||..|.||||||||||.|.| ||||||||||.
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesa
FVNKVYGFYEECQKRYQSVrMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHD--------------GKERLVADLLWADPISGLSGFMENNRGAGCGF
.|..||||.||..||.. .. .|.||||.|||. |...||||.||||||. . .. |..||||.|| . |. ||.|| |
sinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftf
GRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
|.|.| |......||||.||||||.||||||| |.|||.||||.|||.|||..| .| ||.| .||.||.|..
gkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpak
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 25-283 | 2.1e-104 | 341.6 | In-house | 4-275 (280) | alignment | ||
Range on Protein: 25-283
Range on HMM: 4-275/280.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
..| | . .... .... |..|||..||..||||.|||..|||||| | ..|| |||||||||||||. .| |.|||||||..| |...||||||.
acikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhev
EFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSP--------------SHDGKERLVADLLWADPISGLSGFMENNRGAGCG
.|. |||..|...|| | ... ||.... |||. |.. .|||||||||. . .| | ||||||| . ..|. ||.||.
isinrkygfkdevkrry.slalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvi
FGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPT
|| . | ... ...|||.| ||||||||||||..||||.||||.|.|.||| || . ||.|. |||.|.|
fganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa
|
|||||||||
PP2Ac_SM00156 | 30-283 | 1e-99 | 326.0 | In-house | 4-270 (271) | alignment | |||
Range on Protein: 30-283
Range on HMM: 4-270/271.0
GRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNK
||.||. . ...|..|..||..||. |.||||||. |||||....| ||. .|.||||||||| .|||.|.||.|.|...| ...|||||||.. |||
eevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvnk
VYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSP--------------SHDGKERLVADLLWADPISGLSGFMENNRGAGCGFGRDA
.|||.||.. .| . ... |...|..|||. |. .||||||||||| .. .| |..||||.|| . .|| . ||... ||.||
iygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFgeda
VLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPT
| .... ..|.||.|||.||..|||||| .|||||||||.||..|.| ||... ...|..|.| |...
vkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
|
|||||||||
0045823 | Metallo-dependent phosphatases | 9-284 | 1.1e-98 | 323.9 | In-house | 25-325 (473) | alignment | ||
Range on Protein: 9-284
Range on HMM: 25-325/473.0
IIIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYK
. . .|.. .. . ....| .||||| | ...|......|....| |.||||||. |||||... |.|| ...||||.|||| .|.|.. ||||.|
lglldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalk
VKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKERLVA--------------DLLWADPi
.|.||| ||||||||. ..| .|||..|. ..| ..... .|......|||. .| .|||..||||||... . ... ||||.||
ikypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.
SGLSG--------FMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRK------LVTIFSAPHYCGQFDNCAAFMSCDEKLqCSFEIL
.| |. . ||||. ||.||| .......||||.|.|..|..|||.. ..| ..|.||||.|||...|.||.. ||.| .|| ..
weddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqf
RPTS
.|..
dpsp
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 31-283 | 1.7e-96 | 316.0 | In-house | 7-274 (284) | alignment | ||
Range on Protein: 31-283
Range on HMM: 7-274/284.0
RVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKV
| || |...|..| ..|.|.||..|||||||| |||||| . |.| |||||||||||||. .|||.||.|||| || .|.||||||| ..||.
dvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinki
YGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH-------------DG--KERLVADLLWADPISGLSGFMENNRGAGCGFGRDA
||||||||.||. ....|. || .|| |. ..|||||||.| | . | |.||.|| |. | || || ||
ygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsda
VLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPT
. |. ...||. |||||||||||||| |.|||||||| |||||||.|| | ...| ||| .|||
lrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrpr
|
|||||||||
0049330 | Metallo-dependent phosphatases | 5-284 | 2.2e-94 | 309.0 | In-house | 8-300 (309) | alignment | ||
Range on Protein: 5-284
Range on HMM: 8-300/309.0
VVDNIIIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLL
.....|...|.. .. | ...| .|.||. | ...| .....|....| |.||||||. |||||... |.|| ...||||.|||| .|.|.. ||
lllelilslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevllll
LAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQsVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKERLVA--------------DLLW
||.|...|.| ||||||||. ..| .|||..|.. .| .... .|.|....|||. .| .||||.||||||.. . . . ||||
lalkllypdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllw
ADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
.||. .|| .| ||.|. || .|| ... ..||||.|.|..|..||..|...||.|.||||.|||...|..|.. ||.| .|| ...|..
sdplpiregfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvp
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 26-282 | 3e-94 | 308.6 | In-house | 7-282 (284) | alignment | ||
Range on Protein: 26-282
Range on HMM: 7-282/284.0
VITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWP------PTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLR
...| ...| | ..| ..| .|..||.|..||||||| ||| |.. ||| .||||||||||| |||| |.||.|||...| ..||||
llkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllr
GNHECEFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH------DGKE--------RLVADLLWADPISGLSGFMENNR
|||| ||. ||||.||.||| |.... ||| || .||| ....||.|||||.| | | ..||| |||| . ..|. | .|
gnhesrpvnmqygfyleckkry.sealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykespr
GAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRP
||| || .|| . . |||||. ||||||.||||||| |||||||||| ||||.|| || .. ||.| .|| .|.|
gagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp
|
|||||||||
PPP_3 | 29-280 | 1.9e-92 | 302.1 | In-house | 4-269 (271) | alignment | |||
Range on Protein: 29-280
Range on HMM: 4-269/271.0
EGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVN
| . .|.. . .... ....||..||..||||||||. |||.||. || .|. .||||||||||| .|.|...||||.|.|.| ...|||||||.. .|
enelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrqin
KVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLLWADPISGLSGFMENNRGAGCGFGRD
|||||..|..|.... ......|.||..|||. || .|.|..||||||| . .| .. |||. .. . .|. ...||||. || |
kvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFgpd
AVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEIL
.. ..... ||.||.|||.....|||... .|.||.||||.||....| .|... .|.|...|..|
vteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 6-283 | 5.4e-90 | 294.9 | In-house | 3-294 (300) | alignment | ||
Range on Protein: 6-283
Range on HMM: 3-294/300.0
VDNIIIDVLSASTHEKLLSEVI-TEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLL
.|.|| .| | | .| . .|.. | ..| | ...|.. ..|. ||.|||. |||||| . |.||.|||||||||||||. |.|||.||
ideiiqklldagyaakrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletilll
LAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKE--------------RLVADLLW
|.||.|.| |.||||||||| | .|||||.||..| .... .| | || |||. ..| ||.|.|||||| . . |. ||||
lcykikypenffllrgnhecanvtrvygfydeckrrc.nikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllw
ADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPT
.|| . .|.|| . . |. |. | .||.|||| ||.|||||| | |||.|||| |||.||| | || | | ||||.| |
sdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldpl
|
|||||||||
0053225 | Metallo-dependent phosphatases | 10-282 | 1.9e-87 | 286.3 | In-house | 5-290 (293) | alignment | ||
Range on Protein: 10-282
Range on HMM: 5-290/293.0
IIDVLSASTHEKLLSEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKV
|. .|.. .. || ...| .|.||..| ...|......|....| |.|||||.. |||.|... |.||. ...||||.|||| .|.|.. ||||.|.
illlldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkl
KFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKE--------------RLVADLLWADPIs
..|.| .|||||||. ..| .|||..|. .| . ... ...|....|||. || .|||..||||||... . .|..|||| ||
lypdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.
GLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRP
||.. . ||.|. || .|||... ..||||.|.||||.|||... ..||||.||||.|.|...|..|.. ||.| ..| ...|
lwsgwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfap
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 82-284 | 2.3e-83 | 273.0 | In-house | 101-316 (317) | alignment | ||
Range on Protein: 82-284
Range on HMM: 101-316/317.0
ANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH---
.||||||||||| |||| ..||.|.|...| ..|||||||| ||. ||||.|..||| |.... ||| .|| |||| ....||||||||.| .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry.saalyeafqlafnvlplcavvnkkilcmhGGiseelldl
---DGKE--------RLVADLLWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFM
| . ..||| |||| . .|. | .|||| || .|| . . ..|||. ||||||.|||||||.|||||||||| ||||.|| || .
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl
SCDEKLQCSFEILRPTS
| |.||..|...||| |
svdkklkisinvlrpes
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 25-284 | 3.1e-83 | 272.0 | In-house | 8-283 (287) | alignment | ||
Range on Protein: 25-284
Range on HMM: 8-283/287.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
. ... .|..|. . .... ....|..|||...||||||. ||||.|. | .| .||||||||||| |.| ..||...|...| .. |||||||.
dafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhev
EFVNKVYGFYEECQKRYQsVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG----------------KERLVADLLWADPISGLSGFMEN-NRGA
. .||.|||.|| ....| |.. |.|||. |||| ....|||||||.|| . .| |. ||||||| .| | |.
kkinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkirai
GCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
||. | ... ...||| |||.|...||.|.. ..|||.||||.|.|. |..| . .. |. || |.|
svvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkped
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 28-284 | 1.9e-82 | 269.7 | In-house | 9-278 (281) | alignment | ||
Range on Protein: 28-284
Range on HMM: 9-278/281.0
TEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFV
|. . ... . .| .|..||...||.| ||.|.|| || |||. | .| ..||||||||| |.|...||...|.... ...||||||| |
tkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasv
NKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH----DGKER----------LVADLLWADPISGLSGFMENNRGAGCGFGR
||.||||.||. .| . ... || || ||. .|||...||||||||| . ..| || ||||||| . .... ||.. ||.
nkiygfyvecvtky.GeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGk
DAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
. | .|| ....|| ||||||||||| ..||||.|.||.| || .. |.|| . ||.|. |. | |.|
nvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpas
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 24-281 | 2.6e-79 | 259.4 | In-house | 13-283 (288) | alignment | ||
Range on Protein: 24-281
Range on HMM: 13-283/288.0
SEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHE
.|.|.| | .| | ... . . ....|. ||||||||| |||.||. || | |||||||.|||| .|.||..||||.||..| .. |.|||||
celikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhe
CEFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLLWADPISGlSGFMENNRGAGC
. . .|||||.|| ..| |.... .||..|.|. .| .||.|.||||||| . .| ..||||.|| .|. ||||
srqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpeda.egwavsprgagy
GFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILR
|| |.| . ... ...|||||||.|..|| . .|..|..||| || . | || . ||.|. |.|.
lfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 25-283 | 3.1e-79 | 259.2 | In-house | 15-286 (290) | alignment | ||
Range on Protein: 25-283
Range on HMM: 15-286/290.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
. ..| .| .| . | ....... . |...|. ||||.|||| ||| ||. || | .|||||||||||| .|.||. || | ||... . .||||||
kqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhes
EFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLLWADPIsGLSGFMENNRGAGCG
. .|||||.|| ..| . ... | |.|..|||..|. ..|.|.||||||| | .| ..||||.|| .|. .||||
rqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgisprgagyt
FGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPT
||.| | .| || ||||.| .||.. |..||||||| || . | || . |.||. || |.
fgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpa
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 25-282 | 8.5e-73 | 238.2 | In-house | 4-274 (280) | alignment | ||
Range on Protein: 25-282
Range on HMM: 4-274/280.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
.|.| .. .. . .| . ..| .||||| |||| |. |. ||| | | . .||||||||| || ..||.. |... ..|||||||
nvmtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhet
EFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHD--------------GKERLVADLLWADPISGLSGFMENNRGAGCG
|||.|||| ||| .| | .. || .|| .|..|||....||||||||| |. ||||.|| |.. . ||
psvnkiygfyvecqyky.gvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisym
FGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRP
||. | . | ...||| |||||||||||..|||.|.|.|| | || || |.|| . . .|| ||. | |
fgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlip
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 25-280 | 3.2e-72 | 236.1 | In-house | 13-281 (290) | alignment | ||
Range on Protein: 25-280
Range on HMM: 13-281/290.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
. ..| . || || ||.. .. ... ...|. ||||||||| ||. ||. || | ..|.||||.|||| .|.||. .||. |.|.| .. |||||||.
kylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhes
EFVNKVYGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKER--------------LVADLLWADPiSGLSGFMENNRGAGCG
. .|||||.||...| .. . . .||. |... .| ...||.|||||| .. ..||.|.|| .. .. .||||
rqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edvetwavsprgagyl
FGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEIL
||. . . .. .|.|||||||.|..|.... ||||..||| || . | |. .. ... . .....
fgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklf
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 26-274 | 2.2e-71 | 233.5 | In-house | 33-300 (322) | alignment | ||
Range on Protein: 26-274
Range on HMM: 33-300/322.0
VITEGRVLKLLDLALDVFKRQKSMVEMNAP----IKVCGDIHGQFPDLLRLFHRGGWPPT-ANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRG
. . .||.| | ...|.. |.||.. . . ||||||||| ||| .|. | | . ||| ||.|||| ||.|.|..||..|. .| ..|| ||
klhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrG
NHECEFVNKVYGFYEECQKRYQSvRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH---------------DGKERLVADLLWADPISgLSGFMENNR
||| . .||.||| .|....|.. ... |..|||||||. .| .|.| .|||| .. . .| |. .|||.|| . .| .. .|
nhesdnmnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqe.anGrspskr
GAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSC-DEKLQ
| |. || | | . . .|.|| |.|.| ..|||. ||.|.|||| || | .| .||.. ...|.
GvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlk
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 25-271 | 2.6e-67 | 220.5 | In-house | 34-311 (452) | alignment | ||
Range on Protein: 25-271
Range on HMM: 34-311/452.0
E-----VITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLR
..| .||... | ...|..|...|..||| |.||||||| |||.||. || | ...||||||||||| ||||... |.| |...| .|||||
hflkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllr
GNHECEFVNKVYGFYEECQKRYqSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLLWADPISGLSGFM----
||||| . . . | |||...| | ... |. . |. ||| |. .. ||.|||||| . .. ||||.||. . ..
Gnhecrhlteyftfkeeckiky.seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteek
--EN-NRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAG------RKLVTIFSAPHYCGQFDNCAAFMSCDE
.| || . .. || . . .| | |||.. ..||. . |.|.|||| |.. ..| || . ..
fvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyen
|
|||||||||
PPP_1 | 31-180 | 5.4e-67 | 218.8 | In-house | 5-154 (264) | alignment | |||
Range on Protein: 31-180
Range on HMM: 5-154/264.0
RVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKV
. .|.. . ....... ..|....|.||||||||| |||.||. || .|. |||||||||||| .|.|...||||.|.|.| .|||||||||.. |.||
elaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvtkv
YGFYEECQKRYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG
|||..|..|...| ... ...|||..|||. || .|||..||||||. |
ygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldl
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 24-280 | 1.7e-65 | 214.3 | In-house | 11-293 (300) | alignment | ||
Range on Protein: 24-280
Range on HMM: 11-293/300.0
SEVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHE
.|.. | | .| | ... .. ..|...|. | ||.|||| |.| .|. || | .|||||||||||| .|.|||.||.. |...| . |||||||
aellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhe
CEFVNKVYGFYEECQKRY-QSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLLWADPI---------SGLSG
. .||||| || ..| |.. . ..|..| |. .| ..| |.||||||| .| .|||||.|| .|
srqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdreg
--FMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEIL
|.. .|||| .|.| |.| ... | ||||....||. . || |..||| || . | |. . ||.. |..
qhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvy
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 39-286 | 2.3e-65 | 213.8 | In-house | 32-295 (307) | alignment | ||
Range on Protein: 39-286
Range on HMM: 32-295/307.0
ALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQ
| .| .|..|... | | ||.|||| ||. .| | || . |.| ||||||| .|.|.|.||..||. .| |. ||||||| ||| |||||||
aqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecv
KRYQS--VRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGK--------------ERLVADLLWADPISGLSGFMENNRGAGCGFGRDAVLKVCSD
... || .|| ||. ||| |||||||||||. .| |.||||| . . ||.| || . . ||
tsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnviddvckr
FKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTSGR
. ..|| ||||.. ||| ..||||.|||||| || . |. . . || | . |.|
lgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpesen
|
|||||||||
PPP_2 | 56-234 | 4.3e-65 | 212.1 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 56-234
Range on HMM: 1-197/198.0
IKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDVFN
..||||.|||. |||.||. |. .|. .|||||||||||..|.|...||||.|...| ...|||||||.. |||||||..|..|.... ......|.||.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
WLPLCGLIANKILCMHGGLSPSHDG--------------KERLVADLL----WADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQV
.|||. || .|.|..|||||.. . .| .. ||| . || . ... ...||||. ||.|.. ......||.||.|||.|
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 49-284 | 2.1e-63 | 207.4 | In-house | 2-257 (263) | alignment | ||
Range on Protein: 49-284
Range on HMM: 2-257/263.0
MVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRM--
..|..|||..||| |||. ||||.| | ..||||||||||| .|.| |.||.. |. .| ...||||||| . .|| |||. | .||.| .
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye
--FTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG---------------KERLVADLLWADPISGLSGFMENN-RGAGCGFGRDAVLKVCSDFKLDLI
. |..||...||| .....|||||||.|| | .||||||| || |. | ||. | .| . .|||
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidli
CRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRPTS
||||||. || ||| |.|.|.||| .| .. | || . .. |. || |.|
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkped
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 83-284 | 1.4e-62 | 204.8 | In-house | 121-335 (339) | alignment | ||
Range on Protein: 83-284
Range on HMM: 121-335/339.0
NYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSvRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGK-
||||||||||| ||.| ..|| | |. .| ..||||||| || |||| | . ||.. ... .||..|| .|.| .| | |.|||||.|
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsfn
-------------ERLVADLLWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMS
...|| |||| |. ||| || |. . . |... | ||||.|||||| ||.|||||||| |||| || || .|
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
CDEKLQCSFEILRPTS
|.||. | ...|| |
idkklkisinvfrpes
|
|||||||||
PPP_4 | 56-234 | 8.6e-62 | 201.7 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 56-234
Range on HMM: 1-196/197.0
IKVCGDIHGQFPDL-LRLFHRGGWPP-TANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRyQSVRMFTAFQDV
. |.||||||. || |.|.. || |. . .|.||||||||| .|.|...||||.|...| ...|||||||.. .|..|||..|.... .. ... ..|||
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FNWLPLCGLIANKILCMHGGLSPSHD---GK------------ERLVADL-LWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQV
|..|||. ||..|.|..|||||.. . . | . || ||.|| . .|. .. ||||. ||.|.. |.... .|.||.|.|..
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 28-282 | 1.4e-60 | 198.0 | In-house | 7-299 (302) | alignment | ||
Range on Protein: 28-282
Range on HMM: 7-299/302.0
TEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWP-----------PTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLF
.. .|.|.. . .|..|...|. .|. . |||||||.||.|.. . ..|||||||||. ||| | |..|.|| .| |
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi
LLRGNHECEFVNKVYGFYEECQKRYQ---SVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG---------------KERLVADLLWADPISG--
|||||||.. .| ||| || ..|. ... |..|| ..|| |. .||||.|||.|| . .. | |||.|||. .
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvql
------LSGFMENN-RGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRP
...|. || | || .|| . |.|| ||||.. |. ||| .||.|||||| | . || | . | . . | .||.
laavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 28-282 | 2.8e-60 | 197.1 | In-house | 8-300 (302) | alignment | ||
Range on Protein: 28-282
Range on HMM: 8-300/302.0
TEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWP-----------PTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLF
.. .|.|.. . .|..|...|. .|. . |||||||.||.|.. . ..|||||||||. ||| | |..|.|| .| |
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi
LLRGNHECEFVNKVYGFYEECQKRYQ---SVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG---------------KERLVADLLWADPISG--
|||||||.. .| ||| || ..|. ... |..|| ..|| |. .||||.|||.|| . .. | |||.|||. .
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvql
------LSGFMEN-NRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSFEILRP
...| || | || .|| ..|.|| ||||.. |. ||| .||.|||||| | . || | . | . . | .||.
laavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
|
|||||||||
PPP_5_Dcr2 | 56-235 | 1.3e-59 | 194.5 | In-house | 1-199 (199) | alignment | |||
Range on Protein: 56-235
Range on HMM: 1-199/199.0
IKVCGDIHGQFPDL-LRLFHRGGWPP-TANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQKRYQSVRMFTAFQDV
. ||||.|||. || |.||..|| |. . .|.|||||||||..|.|...||||.|...| ...|||||||.| .|..|||..|....|.. ... ...||
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FNWLPLCGLIANKILCMHGGLSPSHDG---------------KERLVADL-LWADPISGLSG-FMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVV
|.||||. ||..|.|..||||||. . .. ||| ||.|| . .| . .. ||||. ||.|.. |.... .|.||.|.|...
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 25-180 | 9.8e-52 | 168.8 | In-house | 14-168 (290) | alignment | ||
Range on Protein: 25-180
Range on HMM: 14-168/290.0
EVITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHEC
. ... .|..|. . .... ...|..||| . ||||||. .||| |. | || ..|||||||||| |.| .||. ||.... .. |||||||.
dafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhev
EFVNKVYGFYEECQKRyQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDG
||..|||.|| .. .. |.. .||||. |.|| ...||||||||.|. .
rkvnrlygfkeelark.rgsrlwkqyqdvfaelslcarvgrkilcmhggisqkies
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 33-269 | 1.1e-49 | 162.4 | In-house | 3-276 (290) | alignment | ||
Range on Protein: 33-269
Range on HMM: 3-276/290.0
LKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLR---LFHRGG-WPPTANYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEFVN
| | | |.|.. .. ..|...|. | ||.||.. || . | | |..|||||||||| ||.| | ||| || .| ..||||||| | |
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq
KVYGFYEECQKRYQ--SVRMFTAFQDVFNWLPLCGLIANKILCMHGGL----------SPSHDGKER---------LVADLLWADPISG-----------
. . .. |.. .. .. ||..||..||| | .|..|.|.|. |. .| || | |.||.|| ..
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl
LSGFMENN-RGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSC
||..|. || |. |. ||. . |. . |||.| . |... . .|.|.||. .|||. .. | .
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvd
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 55-235 | 8.5e-44 | 143.2 | Pfam-A | 2-199 (200) | alignment | ||
Range on Protein: 55-235
Range on HMM: 2-199/200.0
PIKVCGDIHGQFPDL----LRLFHRGGWPPTANYLFLGDYVDRGRFSIETIVLL--LAYKVKFPGNLFLLRGNHECEFVNKVYGFYEECQK---------
.| |.||.||.. || |.|.. .. .. ..|||||.||||. |.||. || |..|...|...||||||||. ..|..|||..|. |
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
------------------------RYQSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSHDGKERLvadllwadpisglsgfmennrgAGCGFGRDA
. . . .....|..|||. |. .|||..||.||.| . . ... ||.||
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi......................gselfgpda
VLKVCSDFKLDLICRAHQVV
. | . . ..||..|.|. .
lekllekygvdlvlrGHtHk
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 32-178 | 3.1e-41 | 134.3 | In-house | 38-191 (383) | alignment | ||
Range on Protein: 32-178
Range on HMM: 38-191/383.0
VLKLLDLALDVFKRQKSMVE----MNAPIKVCGDIHGQFPDLLRLFHRGGWPPTA-NYLFLGDYVDRGRFSIETIVLLLAYKVKFPGNLFLLRGNHECEF
||..| | .|.|. ... . . . ||||.||.. ||| .... | | . .|.| ||.||||. |.| ...|||. . .| ...| |||||
vllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhi
VNKVYGFYEECQKRY--QSVRMFTAFQDVFNWLPLCGLIANKILCMHGGLSPSH
.| ||| | ...| .. .. . ..||| ||||. || .||| .|||.| .
lnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdkt
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 180-283 | 4.1e-23 | 74.8 | In-house | 184-289 (290) | alignment | ||
Range on Protein: 180-283
Range on HMM: 184-289/290.0
GKERLVADLLWADPISG-LSG-FMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSF
.| |. ||||||| .. |. ||.... ... . |.|| |||.| ..|..| .||||.||||.|.|. |. | . | |. |.
cdeglqvdllwadptrdkddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsi
EILRPT
.|.|
vvlkpr
|
|||||||||
PPP_1 | 187-268 | 4.3e-23 | 74.9 | In-house | 182-263 (264) | alignment | |||
Range on Protein: 187-268
Range on HMM: 182-263/264.0
DLLWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMS
| |. |. . ... ...||||. ||.|.. |... ..|.||.|||.|...||||.. ||.||||||. |. ...| .|...
dillsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 183-275 | 3.3e-18 | 58.5 | In-house | 235-327 (383) | alignment | ||
Range on Protein: 183-275
Range on HMM: 235-327/383.0
RLVADLLWADPISGLSGFMENNRGAGCGFGRDAVLKVCSDFKLDLICRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQC
| | |.||.|| . . . ||.|. || | |. . ..|.|. |.|. ..|||| .|..||||| | . | |.. ..|.
rqvldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltp
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 26-81 | 1.5e-11 | 37.0 | In-house | 8-63 (317) | alignment | ||
Range on Protein: 26-81
Range on HMM: 8-63/317.0
VITEGRVLKLLDLALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPPT
...| ...| | ..| ... ..|..||....||||||| ||| |.. ||| .
lfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpls
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 39-80 | 2e-07 | 23.5 | In-house | 23-64 (339) | alignment | ||
Range on Protein: 39-80
Range on HMM: 23-64/339.0
ALDVFKRQKSMVEMNAPIKVCGDIHGQFPDLLRLFHRGGWPP
| .. . .....||| | ||||||| ||| .. |||
areliwsepiflkleapicvmgdihgqfddllamldmngwpl
|
|||||||||
subfamily_YNL217W_pd | Subfamily YNL217W | 53-159 | 2.6e-07 | 23.4 | In-house | 9-120 (235) | alignment | ||
Range on Protein: 53-159
Range on HMM: 9-120/235.0
NAPIKVCGDIHGQFPDLLRLFH--RGGWPPTANYLFLGDYVDRGRFSIETIVLLlaykvkFPGNLFLLRGNHECEFVNK------VYGFYEE-CQKRYQS
. . | ||.|| . .|..|.. || . . ...|| ...| |.|.. .. . ..|||| . . |. . ....
gkrllvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllaykwvkkpkgaeplefsskfsf
V--RMFTAFQDVFNWLPL
. .. | . |.
lesklskadmeyarelgf
|