Gene C52E4.7 in Caenorhabditis elegans

Synonym: CELE_C52E4.7, C52E4.7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily STS
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP041_AA protein Get Run
CeleP041_AA_32-233 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 33-227 4.3e-81 262.6 In-house 1-210 (229) alignment 
Range on Protein: 33-227
Range on HMM: 1-210/229.0
EIIVMRCAETINEIFSDWTKRANLdENKYTPFDVNAPIELPRRTdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
|..|.|.||...|.|..|.|.|.| |.||.|.|.|.|.|||.|.   |||.||||..|.||||||.|.|.|.||...|||.|||||..||.||.|.....
evvvirsaervdevfgkWiksadl.etkyrpldinvPkelpkra...ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkgl

GEKCGAIRIEPELSTLHKSAHVFFGPNHFTSLGYGIDEK-NPLHAVSDGVSLSDLVNRIKRAFYELTSKVDNALIIV------------------DSLSM
|.|..||..||.|....|...|...|..|..|||..||| .||...|...||||.|.||..||..|.|||...||.|                  |.|..
GlkraaisvePgLleyrkarevllppkafkklgypvdekYkPlkelsmaeslsdfvariqaafkkllskveqklilvvadnvsleltrredvesvddllv

MIISSLFHNVYIRN
.........|.|.|
llkktpalsvvivn
subfamily_STS_pd Subfamily STS 33-238 2.3e-59 192.8 In-house 2-213 (245) alignment 
Range on Protein: 33-238
Range on HMM: 2-213/245.0
EIIVMRCAETINEIFSDWTKrANLdENKYTPFDVNAPIELPRRTDMLKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
.|...|..|...|.|..|.| ..  |.||...|.|.| |||||.|.||.|. |||..|.|.|..|...|.|..... ...|||||.. ...||. | ...
tiyivRhgeRvdevfgkWlk.sfd.egkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl

GeKCGAIRIEPELSTLHKSAH----VFFGPNHFTSLGYGIDEKN-PLHAVSD---GVSLSDLVNRIKRAFYELTSKV--DNALIIVDSLSMMIISSLFHN
| |. .|..||.| . .|...    ....|.........|||.. |....|.   . | ..|..|||....|...||  |....||.. ......|  ..
g.kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslselkskeseeelyeRikkvvkeiiekvpedgniliVahaatldalsrqll

VYIrNDSSVDLERLRS
 .  ...|.||..|  
gls.presedlkklvi
0048955 Phosphoglycerate mutase-like 33-223 4.8e-15 48.6 In-house 2-195 (240) alignment 
Range on Protein: 33-223
Range on HMM: 2-195/240.0
EIIVMRCAETINEIFSDWTKranldenkytpfdvnapielprrtdmlksyNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYI
.....| .|.    . ...                                 |.|..|.|.  ...... | |..  ......||   ...||..| ...
rlyLvRHGesewnaegrlqg..............................wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaeal

GEKCGAIRIEPELSTLH----------------KSAHVFFGPNHFTSLGYGIDEKNPLHAV-------------SDGVSLSDLVNRIKRAFYELTS----
| ..  ....|.|  ..                . . | .  .... . ....  ..|. .              .| || |...|...|. || .    
glpllpvvvdprlrErdfgalegltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralk

KVDNALIIVDSLSMMIISSLFHNV
. .| |..  . ... . . ....
pgknvlvVsHggvirallayllgl
0051064 Phosphoglycerate mutase-like 34-222 9.6e-15 47.7 In-house 6-197 (241) alignment 
Range on Protein: 34-222
Range on HMM: 6-197/241.0
IIVMRCAETINEIFSDWTKranldenkytpfdvnapielprrtdmlksyNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIG
....| .|.       ..                                 |.|..|.|.  ...... | |..  ......||   ...||..| ...|
lyLvRHGesewnaegrlqg..............................wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealg

EKCGAIRIEPELSTLH----------------KSAHVFFGPNHFTSLGYGIDEKNPLHAV-------------SDGVSLSDLVNRIKRAFYELTSK----
 ..  ....|.|  ..                . ..|..  .... . ....  ..|...              .| || |...|...|. || ..    
lpllpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllld

VDNALIIVDSLSMMIISSLFHN
 .| |..  . ..... . ...
gknvlvVsHggvirallayllg
0035570 Phosphoglycerate mutase-like 81-233 2.8e-13 42.4 In-house 20-173 (219) alignment 
Range on Protein: 81-233
Range on HMM: 20-173/219.0
SynlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigeKCGaIRIEPELSTLHKSA----HVFFGPNHFTSLGYGIDEKNPLHA
.   |.|..|.|.  ...... | |..  . ....||   ...||..|      ..  ..|.|.|  ..  .    ..    ...  . . . .  . ..
g...dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii......glp.veidprLrEidfgdlegltldeiaekypeelaawlrdpydyr

VSDGVSLSDLVNRIKRAFYELtSKVDNALIIVDSLSMMIISSLFHN--------VYIRNDSSVDL
 ..| || |.|.|...|. ||  . .| |.. .. .. .. ... .        . . |.| . |
ppggEsladvvaRvlpaleel.edgenvlvVsHggvirallayllglpleeilrlnlpngsvtvl
0043909 Phosphoglycerate mutase-like 84-223 2.7e-11 35.9 In-house 25-201 (249) alignment 
Range on Protein: 84-223
Range on HMM: 25-201/249.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTL----------------HKSAHVFFGP---------
||.|..|.|.   ..... | ...  ......||   ...||..| ...|     ....|.|  .                .  ..|..           
lDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlppl

---NHFTSLGYGIDE-----KNPLHAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHNV
   .. . | . .|        .|. . .| || |.|.|...|. ||  .     .| ||.  . .. .. ......
leeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlrallayllgl
0037864 Phosphoglycerate mutase-like 83-223 5.1e-11 34.9 In-house 29-177 (211) alignment 
Range on Protein: 83-223
Range on HMM: 29-177/211.0
NLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTLHKSA----HVFFGPNHFTSLGYGIDEKNPLHAVS
 ||.|..|.|.   ..... | |..  ......||   ...||..| ...|     ....|.|  ..  |    ..    ...  . . .      .. .
wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleeiaekypeelvawlrdpydfrpp

DGVSLSDLVNRIKRAFYELTSKV----DNALIIVDSLSMMIISSLFHNV
.| || |.|.|...|. ||  .     .| |.. .. .. .. ... ..
ggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllgl
0039931 Phosphoglycerate mutase-like 81-229 5.4e-11 34.8 In-house 20-169 (219) alignment 
Range on Protein: 81-229
Range on HMM: 20-169/219.0
SynlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigeKCGaIRIEPELSTLHKSA--------HVFFG---------------
.   |.|..|.|.  .. ... | |..  . ....||   ...||..|      ..  ..|.|.|  ..  .           .                
g...dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii......glp.veidprLrEidfgdlegltleeiaekypeelaawlrdpydyr

PnhftslgygideknplhavSDGVSLSDLVNRIKRAFYELTSkVDNALIIVDSLSMMIISSLFHN--------VYIRNDS
|                   ..| || |.|.|. .|. || .  .| |.. .. .. .. ... .        ... | |
p...................pggEsladvvaRvlpaleella.genvlvVsHggvirallayllglsleeilrlnlpngs
0049178 Phosphoglycerate mutase-like 84-223 5.6e-11 35.1 In-house 26-196 (243) alignment 
Range on Protein: 84-223
Range on HMM: 26-196/243.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTLH----------------KS-------AHVFFGPNH
.|.| .|.|.   . ... | ...  . ....||    ..||..| ...| ..  ....|.|  ..                            .. | .
tDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa

FTSLGYGIDEKNPL----HAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHNV
.. |......  .|    . . .| || |...|...|. ||  .     .. |..  . ..... .|. ..
lllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalllgl
0036777 Phosphoglycerate mutase-like 84-222 6.1e-11 34.9 In-house 25-196 (247) alignment 
Range on Protein: 84-222
Range on HMM: 25-196/247.0
LDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIKSYIGEKCGAIRIEPELSTL-----------------------HKSAHVFFGP--
||.|..|.|.   | ... | ...  . ....||   ...||..| ...|     ....|.|  .                       .   .... |  
lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrppl

----NHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELTSK----VDNALIIVDSLSMMIISSLFHN
      .  | . ..   ||. . .| || |.|.|...|. ||  .     .| |..  . .. .. ... .
lelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayllg
0053607 Phosphoglycerate mutase-like 83-223 5.7e-10 31.6 In-house 22-157 (191) alignment 
Range on Protein: 83-223
Range on HMM: 22-157/191.0
NlDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIksyigekCGAIRIEPELSTLHKS------------------AHVFFGPNHFTSl
  |.|..|.|.   . .|. | ...  . ....||   ...||..|          ....|.|  ..                    |. . .| ...  
g.dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.......glpvevdprlrEidfgdwegltleelaekypeelaawlrdpldyrp.

gygideknplhavSDGVSLSDLVNRIKRAFYELTSkVDNALIIVDSLSMMIISSLFHNV
             ..| || |...|. .|. || .  .|.|.. .. ..... ... ..
.............pggEsladvaaRvlpaleella.ggnvlvVaHggvirallayllgl
0036887 Phosphoglycerate mutase-like 84-224 6.1e-10 31.6 In-house 24-165 (202) alignment 
Range on Protein: 84-224
Range on HMM: 24-165/202.0
LDPPINETGKIASKMIARELCdrHAIPSVIFCSPDFASVETAHLIKSYIGekcGAIRIEPELSTLHKSAHVFF----GPNHFTSLGYGIDEKNPLHAVSD
||.|..|.|.   ..... |   .  . ....||   ...||..| ...|     ....| |  .. .|          ...  . . .    . .....
ldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealg...lpvivdprlrEidfgalegltleeiaekypeelaawlrdpydfrppg

GVSLSDLVNRIKRAFYELTSKV--DNALIIVDSLSMMIISSLFHNVY
| || |.|.|. .|. ||  ..  .| |.. .. .. .. ... .. 
gEsladvvaRvlaaleellarldggnvlvVsHggvlrallayllgls
His_Phos_1 Histidine phosphatase superfamily (branch 1) 34-207 7.1e-09 28.8 Pfam-A 2-149 (158) alignment 
Range on Protein: 34-207
Range on HMM: 2-149/158.0
IIVMRCAETIneifsdwtkrA----NldenkytpfdvnapielprrtdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIK
....| .|.                .                         . . |.|..|.|.   . ....|.. .  ......||   ...||... 
lylvRHGese..........wnkegr........................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeill

SYIGekcGAIRIEPELSTLHKS----AHVFFGPNHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELT---SKVDNALII
  ..     |..||.|  ..       .    ...|    . .....   .. .| || |...|..... ||    .| .| ||.
eeld...ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvliv
His_Phos_1 Histidine phosphatase superfamily (branch 1) 34-207 7.1e-09 28.8 In-house 2-149 (158) alignment 
Range on Protein: 34-207
Range on HMM: 2-149/158.0
IIVMRCAETIneifsdwtkrA----NldenkytpfdvnapielprrtdmlKSYNLDPPINETGKIASKMIARELCDRHAIPSVIFCSPDFASVETAHLIK
....| .|.                .                         . . |.|..|.|.   . ....|.. .  ......||   ...||... 
lylvRHGese..........wnkegr........................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeill

SYIGekcGAIRIEPELSTLHKS----AHVFFGPNHFTSLGYGIDEKNPLHAVSDGVSLSDLVNRIKRAFYELT---SKVDNALII
  ..     |..||.|  ..       .    ...|    . .....   .. .| || |...|..... ||    .| .| ||.
eeld...ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrppegesladvyeRvapfleelieakdkgenvliv
0050036 Phosphoglycerate mutase-like 84-223 6.9e-08 24.6 In-house 23-147 (171) alignment 
Range on Protein: 84-223
Range on HMM: 23-147/171.0
LDPPINETGKIASKMIARELcdrhaIPSVIFCSPDFASVETAHLIKsyigekcGAIRIEPELSTLHKSAHVFFGP--------NhftslgygIDEKNPLH
.|.|..|.|.   . ... |      . ....||   ...||.||          ....|.|  ..  |              .        ..   . .
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil.......lpvivdprLrErdfGawegltldeiaakype........wlldlldl

AVSDGVSLSDLVNRIKRAFYELTskvDNALIIVDSLSMMIISSLFHNV
|. .| || |...|. .|. ||.   .| |..  . ..... .|....
appggEsladvlaRvlpaleell...gnvlvvaHggvirallalllgl