Gene F09C12.8 in Caenorhabditis elegans

Synonym: CELE_F09C12.8, F09C12.8

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily STS
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP056_AA protein Get Run
CeleP056_AA_44-288 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_STS_pd Subfamily STS 47-290 2e-80 261.7 In-house 2-243 (245) alignment 
Range on Protein: 47-290
Range on HMM: 2-243/245.0
VMMVMRHSERVDDCCPGWIEkCNKEGKYEPFDLNMPTRLPIQ-RPLKDYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSG
.....||.||||...  |.. ...|||||..|||.|..|| . ..||||..|...|..|.. |...||.||........|.|||||||||||... .. |
tiyivRhgeRvdevfgkWlk.sfdegkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkglg

SKALLRVEPGLFENFHYPHGV-PRFIS--QLQRHVFPVDKTFRPFLSLETVVGkQETNDEYNARIQLILNAIADQSevstvEKELKVLVVAHASTVDMAV
.|. ..|||||.|.... ..  |...|  .|.......|....|.|||....  .|...|...||. ....|...      ... ..|.||||.|.|.. 
kkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslselks.keseeelyeRikkvvkeiiekv.....pedgniliVahaatldals

GLLREVPrKIREEELDNIAIPVPYCSLAYLK--KKCNYWVPAAHQVPSVT
  | ... . ..|.|....| .||||||.|.  |....|. ......|..
rqllgls.presedlkklvikspycslakleenkeerkwkltdsgilsll
subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 48-242 4.1e-39 125.2 In-house 2-184 (229) alignment 
Range on Protein: 48-242
Range on HMM: 2-184/229.0
MMVMRHSERVDDCCPGWIEKCNKEGKYEPFDLNMPTRLPIQRplKDYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSG-S
..|.|..||||     ||.. . |.||.|.|.|.|  || .   | |  |. .|  | . ...|||.|.     | |..||| ||..|||. . .  | .
vvvirsaervdevfgkWiksadletkyrpldinvPkelpkra..ksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkglGlk

KALLRVEPGLFEnFHYPhgVPRFIS--QLQRHVFPVDKTFRPFlsleTVVGKQETNDEYNARIQLILNAIadqseVSTVEkELKVLVVAHASTVDMAV
.| ..|||||.| ...    . ...  ....  .|||... |       . ..|. ....||||  .. .     .| || . ..||||.. ..... 
raaisvePgLle.yrka..revllppkafkklgypvdekYkPl....kelsmaeslsdfvariqaafkkl.....lskve.qklilvvadnvsleltr
0036887 Phosphoglycerate mutase-like 48-284 3.3e-19 61.8 In-house 4-195 (202) alignment 
Range on Protein: 48-284
Range on HMM: 4-195/202.0
MMVMRHSERV---DDCCPGWIekcnkegkyepfdlnmptrlpiqrplkdytrDTCITRSGAVLAQMIGRGLLmtDNTPDVIYCSPSLRCIQTATWVREMS
  ..|| |..   .. . |..                               |. .|  |   |...|. |.  . ..|..|.|| ||.|||| .. |  
lyLvRHGetewnvegrlqgdl...............................dvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaeal

GSKalLRVEPGLFE-NFHYPHGVPrfiSQLQRHVFPVDKTFRPFLSLETVVGKQETNDEYNARIQLILNAIADQSevstveKELKVLVVAHASTVDMAVG
| .  ..|.|.| | .| . .|..    .  .. .| .   . . .. . . . |.  .. ||.   |......       ..  ||||.|. .. ... 
glp..vivdprlrEidfgaleglt...leeiaekypeelaawlrdpydfrppggEsladvvaRvlaaleellarl......dggnvlvVsHggvlralla

LLREVPrkireeELDNIAIP-VPYCSLAYLKKKCNYWVPAAH
.|  ..        |   .. .|..|.  |  . . ||  ..
yllgls......ledllrlrklpngsvtvlelddggwvlvll
0051064 Phosphoglycerate mutase-like 45-277 7.3e-19 61.1 In-house 3-221 (241) alignment 
Range on Protein: 45-277
Range on HMM: 3-221/241.0
PTVMMVMRHSERVDDCCPGWIEkcnkegkyepfdlnmptrlpiqrplkdyTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMS
..   ..|| |....  . .                                |. .|  |   |...|. |   .  .|..|.|| ||.||||  . |  
mkrlyLvRHGesewnaegrlqg............................wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaeal

GSK-ALLRVEPGLFEnFHYPHGVPRFISQLQRhVFPVDKTFRPFLSLETVV-------------------------GKQETNDEYNARIQLILNAIADQS
| .   ..|.|.| | ....    . ......  || .  .. . .| .                              |. ... ||..  |. .... 
glpllpvvvdprlrE.idfgalegltleeiae.kfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarl

EvstvEKELKVLVVAHASTVDMAVGLLREVPRKireeelDNIAIPVPYCSLAYLKKKCN
.     ..  ||||.|. .. .... |  .| .      . . ...|..|.  |  . .
l....ldgknvlvVsHggvirallayllglple......ellrlnlpngsvtvlelddd
0048955 Phosphoglycerate mutase-like 50-276 1.2e-18 60.3 In-house 5-217 (240) alignment 
Range on Protein: 50-276
Range on HMM: 5-217/240.0
VMRHSERV---DDCCPGwiekcnkegkyepfdlnmptrlpiqrplkdyTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGS
..|| |..   .. . |                                 |  .|  |   |...|. |   .  .|..|.|| ||.|||| .. |  | 
LvRHGesewnaegrlqg...............................wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealgl

K-ALLRVEPGLFENfHYPHGVPRFISQLQRhVFPVDKTFRPFLSLETVV-------------------------GKQETNDEYNARIQLILNAIADQSEV
.   ..|.|.| |  ...    . ......  || .   . . .| . .                            |. ... ||..  |. .... . 
pllpvvvdprlrEr.dfgalegltldeiae.kfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralk

stveKELKVLVVAHASTVDMAVGLLREVPrkirEEELDniAIPVPYCSLAYLKKKC
    ..  ||||.|. .. .... |  .|     ||.    ...|..|.  |  . 
....pgknvlvVsHggvirallayllglp....leeil..rlnipngsvtvleldd
0035570 Phosphoglycerate mutase-like 92-279 3e-16 52.0 In-house 16-180 (219) alignment 
Range on Protein: 92-279
Range on HMM: 16-180/219.0
KDYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVremsGSKalLRVEPGLFENfHYPHGVPRFISQLqRHVFPVDKTFRPFLSLE
. .. |. .|  |   |...|. |   . ..|..|.|| ||.|||| ..    | .  ....|.| |  .. .   . .... .  .| .  ..   .. 
grlqgdvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii....glp..veidprLrEi.dfgdlegltldei.aekypeelaawlrdpyd

TVVGKQETNDEYNARIQLILNAIadqsevstvEKELKVLVVAHASTVDMAVGLLREVPrkireeELDNIAIPVPYCSLAYLKKKCNYW
..  . |.  .. ||..  |...         |..  ||||.|. .. . . .|  .|        .   ...|..|.  |. . . .
yrppggEsladvvaRvlpaleel.........edgenvlvVsHggvirallayllglp......leeilrlnlpngsvtvleldgggg
0039931 Phosphoglycerate mutase-like 93-288 4.9e-16 51.3 In-house 17-189 (219) alignment 
Range on Protein: 93-288
Range on HMM: 17-189/219.0
DYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVremsGSKalLRVEPGLFE-NFHYPHGVPrfISQLQrHVFPVDKTFRPFLSLE
 .. |. .|  |   |. .|. |  ..  .|..|.|| ||.|||| ..    | .  ....|.| | .| .  | .  ..... . .| .  ..   ...
rlqgdspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii....glp..veidprLrEidfgdleglt..leeia.ekypeelaawlrdpyd

TVVGKQETNDEYNARIQLILNAIADqsevstvekELKVLVVAHASTVDMAVGLLREVPrkirEEELDNIaiPVPYCSLAYLKKKCNYWVPAAHQVPS
..  . |.  .. ||.. .|.....         .  ||||.|. .. ... .|  ..     ||. ..  ..|..|.  |. . . ||   . . |
yrppggEsladvvaRvlpaleella.........genvlvVsHggvirallayllgls....leeilrl..nlpngsvtvlelddggwvlvllnlts
0036777 Phosphoglycerate mutase-like 94-279 6.2e-16 51.2 In-house 24-224 (247) alignment 
Range on Protein: 94-279
Range on HMM: 24-224/247.0
YtRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGSK-ALLRVEPGLFEN--------------FHYPHGVPRFISQLQRHVF
   |. .|  |   |. .|. |  .. ..|..|.|| ||.|||| .. |  |     ..|.|.| |                .||.   ..      ...
w.lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyrp

---------PVDKTFRPFLSLETVVGKQETNDEYNARIQLILNAIADQSEvstvEKELKVLVVAHASTVDMAVGLLREVPrkirEEELDNIaiPVPYCSL
           ... | .|.  . .   |.  .. ||..  |. ....       ..  ||||.|. .. . . .|  ..     |.. ..   .|..|.
pllelllelllldllryallpldllpggEsladvvaRvlpaleellarll....kdgenvlvVsHggvlrallayllgls....ledilrl..nlpngsi

AYLKKKCNY--W
  |  . .   |
tvleldddgklw
His_Phos_1 Histidine phosphatase superfamily (branch 1) 49-239 9e-16 51.2 Pfam-A 3-156 (158) alignment 
Range on Protein: 49-239
Range on HMM: 3-156/158.0
MVMRHSERVddccpgwiekCNKEGKyepfdlnmptrlpiqrplkdYTRDT--CITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGs
...|| |..           ||||.                    .. ..   .|  |   |. .|. |   |  .|..|.||..|.||||. ..|  . 
ylvRHGese..........wnkegr....................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld.

kALLRVEPGLFENFHY---PH---GVPRFISQLQRHVFPVDKTFRPFlsletvvgKQETNDEYNARIQLILNAIADqsevsTVEKELKVLVVAHASTVD
   .. ||.| |   .    .    |.    . ...    .| |||         ..|. ... .|.. .|.....       .|. .||.|.|.....
.ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrpp........egesladvyeRvapfleelie.....akdkgenvlivsHggvlr
His_Phos_1 Histidine phosphatase superfamily (branch 1) 49-239 9e-16 51.2 In-house 3-156 (158) alignment 
Range on Protein: 49-239
Range on HMM: 3-156/158.0
MVMRHSERVddccpgwiekCNKEGKyepfdlnmptrlpiqrplkdYTRDT--CITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGs
...|| |..           ||||.                    .. ..   .|  |   |. .|. |   |  .|..|.||..|.||||. ..|  . 
ylvRHGese..........wnkegr....................lqgwsdvpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeld.

kALLRVEPGLFENFHY---PH---GVPRFISQLQRHVFPVDKTFRPFlsletvvgKQETNDEYNARIQLILNAIADqsevsTVEKELKVLVVAHASTVD
   .. ||.| |   .    .    |.    . ...    .| |||         ..|. ... .|.. .|.....       .|. .||.|.|.....
.ipiikeprLrerdfgeweglpkeevkeefpeeyekwkrdkkefrpp........egesladvyeRvapfleelie.....akdkgenvlivsHggvlr
0043909 Phosphoglycerate mutase-like 96-279 2.1e-15 49.4 In-house 25-226 (249) alignment 
Range on Protein: 96-279
Range on HMM: 25-226/249.0
RDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGSK-ALLRVEPGLFEN-------FHY------------------PHGVPRF
 |. .|  |   |...|. |   .  .|..|.|| .|.||||  . |  |     ..|.|.| |         ..                   . .| .
lDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlppl

ISQLQRHVFPV--DKTFRPFLSLETVVGKQETNDEYNARIQLILNAIADQSEvstvEKELKVLVVAHASTVDMAVGLLREVPRKIREEEldniaiPVPYC
.. |. . .    | ..... .|   . . |.  .. ||.   |. ....       ..  ||.|||. .. . . .|  ..     .        .|..
leeldelllellldyaladldplldrppggEsladvvaRvlpaleellarll....kdggnvliVaHggvlrallayllglsledilrl......nlpng

SLAYLKKKCNYW
|.  |  . . .
sitvlelddggk
0037864 Phosphoglycerate mutase-like 95-280 4.8e-15 48.1 In-house 29-203 (211) alignment 
Range on Protein: 95-280
Range on HMM: 29-203/211.0
TRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGSK-ALLRVEPGLFEnFHYPHGVPRFISQLQRhVFPVDKTFRPFLSLETV
  |. .|  |   |...|. |  .. ..|..|.|| ||.||||  . |  |     ..|.|.| | ...     . ......  .| .  .. . .. ..
wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrE.rdfgalegltleeiae.kypeelvawlrdpydfr

VGKQETNDEYNARIQLILNAIADQSevstVEKELKVLVVAHASTVDMAVGLLREVPrkirEEELDNIaiPVPYCSLAYLKKKCNYWV
  . |.  .. ||..  |. .. .     ....  ||||.|. .. . . .|  ..     ||| ..   .|..|.. |. . . ||
ppggEsladvvaRvlpaleellarl....lkdgenvlvVsHggvlrallayllgls....leellrl..nlpngsvtvlelddggwv
0049178 Phosphoglycerate mutase-like 96-282 8.3e-15 47.6 In-house 26-224 (243) alignment 
Range on Protein: 96-282
Range on HMM: 26-224/243.0
RDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMSGSK-ALLRVEPGLFENF--------------HYPHGVPRFISQLQRHVFPV
 |.  |  |   |. .|. |   . ..|..|.|| .|.|||| .. |  | .   ..|.|.| |                .||. . ... .   ...|.
tDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarppa

DKTFRPFLSL-------ETVVGKQETNDEYNARIQLILNAIADQSEvstvEKELKVLVVAHASTVDMAVGLLREVPRKIREeeldniAIPVPYCSLAYLK
  .....|.|         ..   |. ... ||..  |. .. .       ..  ||||||  .  . . ||  .| .          ...|..|.  | 
lllldlllplldrlladldllpggEsladvaaRvlpaleellaell....hdgktvlvVaHggvirallalllglpleell......rlnlpngsvtvle

KKCNYWVPA
 . . ||  
lddggwvlv
0053607 Phosphoglycerate mutase-like 94-280 1.3e-13 43.5 In-house 20-183 (191) alignment 
Range on Protein: 94-280
Range on HMM: 20-183/191.0
YTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVremsGSKalLRVEPGLFENFHYPHGVprFISQLQRHVFPVDKTFR--------
.. |. .|  |   |. ... |   . ..|..|.|| ||..||| ..    | .  ..|.|.| |  .          .  .  .| .   .        
lqgdvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii....glp..vevdprlrEidfgdweg..ltleelaekypeelaawlrdpldyr

PflsletvvGKQETNDEYNARIQLILNAIADqsevstvekELKVLVVAHASTVDMAVGLLREVPrkireeELDNIAIPVPYCSLAYLKKKCNYWV
|         . |. ... ||..  |. ...         .  ||||||. .. ... .|  .|        .   ...|..|.  |  . . ||
p........pggEsladvaaRvlpaleella.........ggnvlvVaHggvirallayllglp......leellrlnlpngsvtvlelddggwv
0050036 Phosphoglycerate mutase-like 96-251 7.1e-11 34.3 In-house 23-150 (171) alignment 
Range on Protein: 96-251
Range on HMM: 23-150/171.0
RDTCITRSGAVLAQMIGRGLlmtdnTPDVIYCSPSLRCIQTATWVRemsgskALLRVEPGLFEnFHYPHGVPRFISQLQRHVFPvdktfRPFLSLETVVG
 |. .|  |   |. .|. |     ..|..|.|| ||..||| ..         ..|.|.| | ...     . ........       . .  |  .. 
tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil......lpvivdprLrE.rdfGawegltldeiaakype.....wlldlldlapp

KQETNDEYNARIQLILNAIAdqsevstvekeLKVLVVAHASTVDMAVGLLREVPRK
  |.  .. ||..  |. ..             ||||||. .. ... || ... .
ggEsladvlaRvlpaleell...........gnvlvvaHggvirallalllglsle
subfamily_TFC7_pd Subfamily TFC7 84-258 8.3e-09 26.4 In-house 17-192 (255) alignment 
Range on Protein: 84-258
Range on HMM: 17-192/255.0
RLPIQRPLKDYTRDTCITRSGAVLAQMIGRGLLMTDNTPDVIYCSPSLRCIQTATWVREMsgSKALLRVEPGLFENFHyPHGVPRFISQL----QRHVFP
..|   ||.    |. ..  |   |. ... |.  |. |..|..||  ||..|.. . |.   .  ..|. |. | .. |   |     .     .. ||
kgpypdpltgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaee..leiPvyvdrGvgewyk.pdrrPvilePasnevlskffP

V--DKTFRPFLsleTVVGKQETNDEYNARIQLILNAIADQSEVSTVEKElKVLVVAHAST-VDMAVGLL-REVPRKIREEELD
   .. . . |   |   |.||..|   |.. .     |. |    . |  .|.|.||.| . .  .||  . ...  .|. .
svisldyestl...tpsekgeteeelyertkkfwpvfidrvekkfknve.tilivthaatkialGmsllkydsakeslnenga