Gene F44B9.9 in Caenorhabditis elegans

Synonym: CELE_F44B9.9, F44B9.9

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP086_AA protein Get Run
CeleP086_AA_2-217 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 3-214 4.4e-53 173.7 In-house 42-327 (473) alignment 
Range on Protein: 3-214
Range on HMM: 42-327/473.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCC
......|. |||...|..|||..| |.|......||||||..|| |||.  .  ..            . |||||.||||. ||....|...|| ..  .
llpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfpped...........rlvflGDlvDrGpdslevlelllalkikypgn

F-----------------------------------------------EN-VI--------------------------------DIILARTFWEDFDAP
.                                               .. ..                                |.  ... ..| |  
vfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPweddgdgl

AKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRK------LCTIFSAPRYMNEIDNSGAVMKVASNGkISISIMKNPNFA
 .  |..|..|| ...|.. ||.| ..  .. ||||||...| |.... |.|      ..|.|||| |... .| .||... ... ||. ...  .  
lrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphp
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 3-101 2.7e-51 167.6 In-house 5-103 (302) alignment 
Range on Protein: 3-101
Range on HMM: 5-103/302.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
.|||.||..|...||||.||||||||||||||||||||||||||||.||.|.|.|.||.|..|.||..|.||||||||||.||..||||||.||.|.  
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 2-101 3.4e-51 167.2 In-house 5-104 (302) alignment 
Range on Protein: 2-101
Range on HMM: 5-104/302.0
RTYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
..|||.||..|...||||.||||||||||||||||||||||||||||.||.|.|.|.||.|..|.||..|.||||||||||.||..||||||.||.|.  
keysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt
0049330 Metallo-dependent phosphatases 4-217 1.2e-47 155.7 In-house 30-305 (309) alignment 
Range on Protein: 4-217
Range on HMM: 30-305/309.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
.|. ||. ||....|..|.|..| |.| .....||||||..|| |||.  .             .  . |||||.||||. ||....|...|| |.   .
lseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfp...........pedrlvflGDlvdrGpdslevlllllalkllypdnv

-----------------------------------------------EN------------------------VID----IILARTFWEDFDApaKPSFI
                                               ..                        ...     .|.   | | .     . .
fllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplp..iregf

RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNFAMKM
..|.|||.|.|.. ||.. .......||.|||.... |...|.|.||.|.||||.|.....| |||... ....||. ...  .. ...
apnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplllll
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 121-210 1.4e-47 155.4 In-house 210-299 (302) alignment 
Range on Protein: 121-210
Range on HMM: 210-299/302.0
APAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
...||....|..|||||.||||||...|. ||..||||.|||.|.|||||||.||.|||||||||||.||.|||.||..|||.|||...|
vsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 122-211 2e-47 154.8 In-house 212-301 (302) alignment 
Range on Protein: 122-211
Range on HMM: 212-301/302.0
PAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNP
..||....|..|||||.||||||...|. ||..||||.|||.|.|||||||.||.|||||||||||.||.|||.||..|||.|||...| 
sekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk
0053225 Metallo-dependent phosphatases 4-207 6.9e-44 143.6 In-house 22-287 (293) alignment 
Range on Protein: 4-207
Range on HMM: 22-287/293.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC--
.|..||. ||....|..|||..| |.| .....|||||...|| .||.  .             .. . |||||.||||. ||....|...|| |.    
lseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfp...........pedrlvflGDlvdrGpdslevlelllalkllypdnv

---------------------CFENVIDIILARTFWEDFDA--------------------------------------------------PAKPSFIRN
                     ...  ..  | . ... ...                                                  |   | .  
vllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlwsgwlp

NKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISI
..|||.|.|.. || . ... .. ||.||||..| |.... |.||.|.||||.|... .| |||... .. .... .
syrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfkl
PP2Ac_SM00156 5-100 1.3e-27 89.6 In-house 2-86 (271) alignment 
Range on Protein: 5-100
Range on HMM: 2-86/271.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLntrnssenaksKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
|| |.. ||. |.|..|.||.| |.|.|||.|||||||..||.|||           .    ....| ||||||||||..|. .|.|.|.|| |..
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll...........elageppeekyvFlGdYVDRGpqsiEvillLfalkilyp
PP2Ac_SM00156 114-210 2.4e-27 88.7 In-house 175-269 (271) alignment 
Range on Protein: 114-210
Range on HMM: 175-269/271.0
TFWEDFdaPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
  |.|     | . ....|||||| |.|.||.|... .|..||.|.|.... |..||||.|| ||||||.|..| .|..||.|| .| |.||  .|.
llwsdp..eqkekgfqpskrglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 123-210 3.4e-27 88.3 In-house 187-274 (280) alignment 
Range on Protein: 123-210
Range on HMM: 187-274/280.0
AKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
 | .   .| || || | .  |.. ...|.| ||.||||..  |..||||.|| |.||||.|..|.||| ||..| .. ..|. ..| 
nkvtgwaensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkp
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 125-210 4.5e-27 87.8 In-house 208-293 (298) alignment 
Range on Protein: 125-210
Range on HMM: 208-293/298.0
PSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
 .   .|.|| || | | .|.. .  |.| |.||.||..  |..|||..|| ||||||.|... ||| ||||| .. ..|  ..| 
vkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkp
subfamily_PPP1C_pd Subfamily PPP1C 112-210 9.1e-25 80.4 In-house 182-278 (282) alignment 
Range on Protein: 112-210
Range on HMM: 182-278/282.0
ARTFWEDFDAPakPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
.  .| | |       . .|.|| |. |.. .|.. ..  ...||||.||.. .|..|||.|.| |.|||| |..|.||.|||..| .. ..| .|.| 
cdllWsdpdke..vlgwsendrGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkp
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 110-209 2.1e-24 79.3 In-house 216-313 (317) alignment 
Range on Protein: 110-209
Range on HMM: 216-313/317.0
ILARTFWEDFDApaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.||   | | ||  . .  .. .|| .  | ..||.| .. |.. |.||.||..  |..||||||| |||||| |  ..|| .||..|... ||||....
vladltwadpda..evkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdkklkisinvlr
PPP_3 4-99 7.8e-24 77.1 In-house 2-86 (271) alignment 
Range on Protein: 4-99
Range on HMM: 2-86/271.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.|..||  |.... |...||..| ||| |||..||||||..||..| ..  .|..           .|..|||||||||.|||....|...|| ..
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspe...........tkYlFlGdyVDrGkkslEvlllLlalkiky
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 115-213 1.2e-23 76.5 In-house 187-284 (287) alignment 
Range on Protein: 115-213
Range on HMM: 187-284/287.0
FWEDFDAPaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNF
.| | .   . .|  |  |..|| | .  |.. .. |.|.|||| |..   |..|..|..| |.||||.|. |  | |||..|.   ..|.  .|  .|
lwadpekd.aktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedf
subfamily_PPP3C_pd Subfamily PPP3C 10-100 3e-23 75.3 In-house 47-126 (452) alignment 
Range on Protein: 10-100
Range on HMM: 47-126/452.0
FCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNtrnssenakskpIYG-FSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
  ..... .|.|||||| |.. |.|..||||||| ||..|..            . |  .. |..|||||||||| |..|.  ...||  ..
lkiieeaakllkkektlleveaPitviGdihGqfydllklfe............vgGdPastkylflGdyvdrGyfsiecvlylyalkiayp
PPP_3 120-209 7.6e-23 73.9 In-house 181-270 (271) alignment 
Range on Protein: 120-209
Range on HMM: 181-270/271.0
DAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
. |.| ....|.|||....| . ...| ..  ...||.| |.. ..|.....|.|. |.|||| |.....| ||..|.... . .. ...
sdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 111-210 3.3e-22 72.3 In-house 185-282 (284) alignment 
Range on Protein: 111-210
Range on HMM: 185-282/284.0
LARTFWEDFDApaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
.|   | | .|  . .  .. .||    | ..||.| ..  .. |.|| ||..  |..||||||| |||||| |  ..|| .||..|...  .|....|.
iadltwadpea..evegykesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp
subfamily_PPP1C_pd Subfamily PPP1C 5-100 4.8e-22 71.5 In-house 11-95 (282) alignment 
Range on Protein: 5-100
Range on HMM: 11-95/282.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
...|.  ||..  |..... .| |.. ||.||||||||..||.||..| .. ...           ...||||||||| .||. |.|....|  ..
keaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpes...........nylflGdyvdrGkqsletivlllaykikyp
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 115-212 9.9e-22 70.5 In-house 200-295 (299) alignment 
Range on Protein: 115-212
Range on HMM: 200-295/299.0
FWEDFDAPAKPsfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPN
.| | |   |    ..| ||.|  | .  |....  |.| |. | ||..  |..|||..|| |||||| |  ..||| |.|||  |   .. ..|  .
lwadpdqsvkd..wlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptp
PPP_1 5-99 1.3e-21 70.1 In-house 2-85 (264) alignment 
Range on Protein: 5-99
Range on HMM: 2-85/264.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
...||. |.... ||..||..| |.| ..|..|||||||.||..| ..  .|..           ....|||||||||..|.....|...||  .
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspe...........tnYlFlGDyVDRGkdSvEilllLlalklky
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 4-103 2.5e-21 69.0 In-house 24-112 (298) alignment 
Range on Protein: 4-103
Range on HMM: 24-112/298.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenaKSKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
 ...... |.... ..||| |.| |. .|... ||||||. ||.||..         . |     .. ..||||||||| ..|. |.|... |  . . |
ikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdk.......agfp....pdanylflGdyvdrGrqnlevivlllaykvkypnnf
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 111-208 9.6e-21 67.2 In-house 179-274 (281) alignment 
Range on Protein: 111-208
Range on HMM: 179-274/281.0
LARTFWEDFDAPAKpsFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIM
.   .| | |  ..    ..  || |  | .. |...|. |.. ||.|.||.. .|.. .. ||| |.||.| | .   |..||.||  . .||.  .
viDllwadpdnkve..ewkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislval
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 115-209 3.1e-20 65.4 In-house 193-287 (290) alignment 
Range on Protein: 115-209
Range on HMM: 193-287/290.0
FWEDFDAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.| | .     ..  | .|..|| | . .... .. | .||||| |..   ||.|  |.|| |.|||| |  .  | ||...|.   ..|| ..|
lwadptrdkddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlk
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 5-98 2.8e-19 62.6 In-house 9-97 (284) alignment 
Range on Protein: 5-98
Range on HMM: 9-97/284.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSS---ENAKSkpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSL
...||. |     ||| |||   ||  ||.||||||||||||. ||.        ..||.        ||..|||||||||  |.. | |.|..| |
kekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeake........kkylflgdyvdrgpfsievitllfaykll
subfamily_PPZ_pd Subfamily PPZ 124-204 4.9e-19 61.9 In-house 207-287 (300) alignment 
Range on Protein: 124-204
Range on HMM: 207-287/300.0
KPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKIS
 .    .|.||.| |.|. |.|.    . . |..| | ..  |..|| || | |.|||| |  |.|| |||| |.     |
ssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcs
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 4-99 5.8e-19 61.4 In-house 8-92 (281) alignment 
Range on Protein: 4-99
Range on HMM: 8-92/281.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
|.| |.  .. .|  .| .||.|.|| .|...|||.|.||.|| ||..  .             . ...|||||||||| .||... |.|.||  .
ytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrv...........peevlvflgdyvdrgpqslevlillftlkiry
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 3-100 6.8e-19 60.9 In-house 9-95 (287) alignment 
Range on Protein: 3-100
Range on HMM: 9-95/287.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..| .... .|. . |...  ..| |.  |.|||||||||..||.|..|    . .            ...||||||||| |||. . |.|||| ...
afsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapk...........vqylflGdyvdrGakslevslllfslkiayp
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 115-214 1.8e-18 60.1 In-house 161-259 (263) alignment 
Range on Protein: 115-214
Range on HMM: 161-259/263.0
FWEDFDAPAKpSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNFA
.| | .  ||  |  |. | .|  | .  |.. |. |.| |||| ||..  |. |||||.| |.||| ||  |. |  ||. |    ..|.  .|  .| 
lwadpekdak.gfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedfe
PPP_1 121-197 2.6e-18 59.3 In-house 188-264 (264) alignment 
Range on Protein: 121-197
Range on HMM: 188-264/264.0
APAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKV
 ... ....|..|| . .|.. .... ..  |..||.| |.. ..|..|...||. |||||. |..| .| ||..|.
dkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 129-209 4.5e-18 58.6 In-house 192-272 (284) alignment 
Range on Protein: 129-209
Range on HMM: 192-272/284.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
  | ||.|  |   |. .    |.| |.|| ||..  |..|||.|.| |||||| |  ..||. ||| |  |   |. ...
npnsrgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlr
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 9-103 8.2e-18 57.7 In-house 28-111 (297) alignment 
Range on Protein: 9-103
Range on HMM: 28-111/297.0
LFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
.. |||. ...||..|.. |.  |. ..||||||| ||.||.            |     | ...|||||||||  |.. | |... |  | . .
vlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrgg.......wp....ptanylflgdyvdrgrfsietivlllaykvkfpgnl
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 126-209 8.7e-18 57.6 In-house 210-293 (297) alignment 
Range on Protein: 126-209
Range on HMM: 210-293/297.0
SFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
| . .|.||  . |   || . |  ... |..| ||..  |..||| ||| ||||||.|  ..||  |.| .  . . |. |..
sgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilr
subfamily_PPP6C_pd Subfamily PPP6C 5-99 1.2e-17 57.0 In-house 16-99 (290) alignment 
Range on Protein: 5-99
Range on HMM: 16-99/290.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSsenakskpiygFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
....|  | |.|..|. .| ..  .| |||..||||||| ||. |..|  .           .  ...|||||.||||| ||. . ....||  .
pendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggq...........vpdtsyvflgdfvdrgyysletftrlltlkaky
PPP_2 33-99 1.4e-17 57.0 In-house 1-56 (198) alignment 
Range on Protein: 33-99
Range on HMM: 1-56/198.0
VTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||..||.|||..||..| ..  .|..           .|..|||||||||.|||....|...||  .
vtvcGDlHGqldDLlilfknglpspe...........rkylFlGdyvDrGkkslEvlllllalklvy
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 110-209 1.9e-17 56.4 In-house 235-332 (339) alignment 
Range on Protein: 110-209
Range on HMM: 235-332/339.0
ILARTFWEDFDAPAKPsfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.|.   | | |   |    .   || |. |   |.    . |.. ...||||..  |..||  |.| |||||| |  . ||. ||. .  . |||| ...
vltdltwadpdptekg..ykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsidkklkisinvfr
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 6-100 2.3e-17 56.0 In-house 8-91 (280) alignment 
Range on Protein: 6-100
Range on HMM: 8-91/280.0
KTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRnssenakSKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..... ... . .... ..|. |.  ||...||.|||. ||.||..         | |      ....||||||||| . |. |.|... |  . 
eadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv.......sfp....pdqnylflgdyvdrgrqqlevillllaykvryp
PPP_4 33-99 5.9e-17 55.3 In-house 1-58 (197) alignment 
Range on Protein: 33-99
Range on HMM: 1-58/197.0
VTIVGDIHGQFEDL-VRLLNtrNSSENA-KskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||.|||||||..|| ..||.  |. ... .         .. ||||||||||..||....|...||  .
vtvvGDiHGqlddlllkllk..ngglpsee.........rsyvflGDyVDRGkdslevlllLlalklvy
subfamily_PPP2C_pd Subfamily PPP2C 7-99 6.2e-17 54.7 In-house 20-101 (290) alignment 
Range on Protein: 7-99
Range on HMM: 20-101/290.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.|.  | ... |...||. . |.. |||..||.|||| ||. |..   .| .            ...|||||||||| |.....|. .||  .
sevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspd...........tnylflgdyvdrgyysvetvtllvalkvry
PPP_5_Dcr2 33-99 1.5e-16 54.0 In-house 1-58 (199) alignment 
Range on Protein: 33-99
Range on HMM: 1-58/199.0
VTIVGDIHGQFEDL-VRLLNTR-NSSEnakskpiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||..||.|||..|| ..|...  . ||           ... ||||||||||..||....|...|| ..
vtvcGDlHGqlddlllilfkeggdpse...........erlyvFlGDyVDrGkdslevlllLlalklvy
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 10-103 2.5e-16 52.9 In-house 9-91 (284) alignment 
Range on Protein: 10-103
Range on HMM: 9-91/284.0
FCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
 .||  ....|.|.  | |.  |. |.||||||| ||.||..       |           ...||||||||| . |. | |.|. | .|   |
etllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphra...........nylflgdyvdrgkhcletilllfaykvifpnhf
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 129-212 4.1e-16 52.3 In-house 193-276 (280) alignment 
Range on Protein: 129-212
Range on HMM: 193-276/280.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPN
  . ||.|  | .. |...|. |.| ||.|.||..  |....| |.| |.|| | |  .. |. ||. . .| ..|.  .  | 
fhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlippp
subfamily_PPP4C_pd Subfamily PPP4C 7-98 5.3e-16 51.7 In-house 19-99 (288) alignment 
Range on Protein: 7-98
Range on HMM: 19-99/288.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSL
.|.  |   . |.. .|  . ..  |||. |||||||.||..|..   . ..           ....||||.||||. |.... |. .||  
eevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpe...........tnylflgdfvdrgfysvetfllllalkvr
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 5-99 6e-16 51.5 In-house 25-108 (299) alignment 
Range on Protein: 5-99
Range on HMM: 25-108/299.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenakSKPiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
 . ||  | ..  . | .. .| |. .|. ..||||||. ||.|...  .        |       ...||||||||| . |. |.|..  |  .
keqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkag......fpp.....dvnflflgdyvdrgrqnlelitlllcfkiky
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 3-100 6.2e-16 51.2 In-house 15-101 (290) alignment 
Range on Protein: 3-100
Range on HMM: 15-101/290.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..|  ... .|. . |...   .| |.  |..||||||||...|.| ..          .|       |..||||||||| |||.   |.| .| ..|
afsdkdileilekieeileplpalleveapivivgdihgqldallryfdavg.......yp....pkvkflflgdyvdrgakslevslllfcykirys
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 112-200 8.4e-16 51.0 In-house 195-281 (307) alignment 
Range on Protein: 112-200
Range on HMM: 195-281/307.0
ARTFWEDFDaPAKPSfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASN
   .| | | |.     .   ||  . |    ... |. | . ||.| |||   |.  .. ||| |||||| | |   |.|.|.||   
ndmlwadpd.psvfe.wkassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdet
subfamily_PPZ_pd Subfamily PPZ 9-99 1.3e-15 50.7 In-house 30-109 (300) alignment 
Range on Protein: 9-99
Range on HMM: 30-109/300.0
LFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenAkskpiyGF-STKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.. .     |||  . .| |.||.| ||||.|||. ||.||.        .      ||  . ...||||||||| .||. | |..  |  .
ilqicikarelflaqpallelspsvkivgdvhgqyadllrlftk......c......gfppsanylflgdyvdrgkqsletillllcykiky
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 4-106 6e-15 48.2 In-house 20-108 (307) alignment 
Range on Protein: 4-106
Range on HMM: 20-108/307.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPIygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSlfsCCF
|.| |.  ..     .|  ||.| .| ||. .|||.||||.||. ..           .|        .|| |||||||  ||.|| |.|. |    |  
ytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillg.......rpp....etvyvftgdyvdrgllslecilllftyki...cyp

ENV
||.
eni
subfamily_PPG1_pd Subfamily PPG1 13-98 1.3e-14 47.1 In-house 23-97 (300) alignment 
Range on Protein: 13-98
Range on HMM: 23-97/300.0
LDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskPiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSL
 | . ||. ||  . ||  |||.|||.|||| |.. ...           |       ...|||||||||. |.. | |.  ||  
tdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqv......p.....dtnylflgdyvdrglysvetisllivlklr
subfamily_PPP5C_pd Subfamily PPP5C 122-205 1.9e-13 43.1 In-house 219-303 (322) alignment 
Range on Protein: 122-205
Range on HMM: 219-303/322.0
PAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKV-ASNGKISI
| . . . . |||..| |     .. ..  |..||.| |..   |...  | || |.|||| | ....| ||.... ... |. .
pqeanGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkf
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 26-97 2.3e-13 43.4 In-house 2-62 (263) alignment 
Range on Protein: 26-97
Range on HMM: 2-62/263.0
LAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakSKpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKS
| |.  |. |.|| |||..||.|..|.  ..    .|        ...||||||||| .||. | |.|||| 
llelqapinicgdthgqyndllrifnacgaa....tk.......tqylflgdyvdrgghslevimllfslkl
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 7-97 3.8e-13 42.5 In-house 9-88 (280) alignment 
Range on Protein: 7-97
Range on HMM: 9-88/280.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenakskpIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKS
 |. ... ||  .| .|  |.|   |. ..|||| |..|. ||..            |     .| .||||||||| . .. . |.| || 
heiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdl...........igrvpeeklmflgdyvdrgpqgievlillfclki
subfamily_PPPLV_pd Subfamily PPPLV 11-101 1.3e-12 40.6 In-house 4-87 (290) alignment 
Range on Protein: 11-101
Range on HMM: 4-87/290.0
CLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLlntrnSSENAKSKPIygFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
.| |. .. . .|. | |.  |. ..||.||...||. .     ..   .  ..  ..  . .|||||||||  |.. |. ...|| |.  
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyf.....ekvlwrtgvd..ltpasllflgdyvdrgdfsveliayllalkvlyps
subfamily_PPP4C_pd Subfamily PPP4C 129-208 1.3e-12 40.5 In-house 203-282 (288) alignment 
Range on Protein: 129-208
Range on HMM: 203-282/288.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIM
    ||    | . .|.. ..  .|.||.| ||..  |.|.  ..|. |..||| |     |  |.... .. .   .|.
avsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif
subfamily_PPPLV_pd Subfamily PPPLV 126-204 1.9e-12 40.1 In-house 205-281 (290) alignment 
Range on Protein: 126-204
Range on HMM: 205-281/290.0
SFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEiDNSGAVMKVaSNGKIS
 |. |..|| .  | |.|..   .  |.| ..| |..  .|...  . .| |.||. ||     |. |.. | .. |. 
GfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs.sneaalilv.dkkklr
subfamily_PPP6C_pd Subfamily PPP6C 129-206 5.2e-12 38.5 In-house 202-279 (290) alignment 
Range on Protein: 129-206
Range on HMM: 202-279/290.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISIS
   .||    | .  ..| ... |..||.| ||..  |.|.. | || |..||| |     |  .....  . . .  
avsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereak
subfamily_PPP5C_pd Subfamily PPP5C 10-100 8.4e-12 37.7 In-house 40-124 (322) alignment 
Range on Protein: 10-100
Range on HMM: 40-124/322.0
FCLLDMVIELFKKEKTLAEISPP----VTIVGDIHGQFEDLVRLLNTRNSSEnaKskpiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
. .| .. ||.||. .| ||. .    .|. ||||||| ||. ...   ..   .        .. ..| ||.||||  |...| .....| |. 
lkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlps..e........enpylfnGdfvdrGsfsveviltllgfkllyP
subfamily_PPP2C_pd Subfamily PPP2C 116-204 1.6e-11 36.9 In-house 194-279 (290) alignment 
Range on Protein: 116-204
Range on HMM: 194-279/290.0
WEDFDapAKPSFiRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKIS
| | |   .  .    .||    | .   ..  .  ...||.| ||..  |...  ||...|||||| | .   | .|....  . | |
wsdpd..drggw.gisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkys
subfamily_PPP3C_pd Subfamily PPP3C 116-201 1.8e-11 36.5 In-house 221-313 (452) alignment 
Range on Protein: 116-201
Range on HMM: 221-313/452.0
WEDFDAPA-KPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFAD------RKLCTIFSAPRYMNEIDNSGAVMKVASNG
 ||..  . . .| .|. || |. .. .|| |  .  ..  |.| |.   ||.. . .        | |.|||| |..  .| .||.|. .| 
ledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv
subfamily_PPP7C_pd Subfamily PPP7C 116-201 2.5e-11 35.9 In-house 242-325 (383) alignment 
Range on Protein: 116-201
Range on HMM: 242-325/383.0
WEDfdAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNG
| |    ||     |  ||  . |     ..  .  |..|..| |.  | |..|  |.|. |||||  | .|  | || .|.... 
wsd..pkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdl
subfamily_PPP7C_pd Subfamily PPP7C 27-99 1.2e-10 33.6 In-house 60-122 (383) alignment 
Range on Protein: 27-99
Range on HMM: 60-122/383.0
AEISPPVTIVGDIHGQFEDLVRLLNtRNSsenakskpiYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
. ||  ||. ||.||...||. .|  .|          .  . . .|| ||.|||| .|.. ......|  ..
taiskevtvcGdlhGklddlllily.knG.........lpseenpyvfnGdfvdrGkesveillillalllvy
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 4-53 2.8e-10 32.9 In-house 9-58 (317) alignment 
Range on Protein: 4-53
Range on HMM: 9-58/317.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTR
....||  |     ||| ||.   |.  |||||||||||||||. ||.  
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldln
subfamily_PPG1_pd Subfamily PPG1 121-203 1.2e-09 30.9 In-house 205-288 (300) alignment 
Range on Protein: 121-203
Range on HMM: 205-288/300.0
APAKPS-FIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKI
 | .   .... .||   .. .  |..  |  ..  |.| ||.   |.. . | ||.|..||| | .   |  ..... .. . 
hpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekder
Metallophos Calcineurin-like phosphoesterase 32-97 1.8e-09 31.2 Pfam-A 2-62 (200) alignment 
Range on Protein: 32-97
Range on HMM: 2-62/200.0
PVTIVGDIHGQFEDLVrllntrNsSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLV--FSLKS
.....||.||...||          ...  | .        .||||.||||  |. ...|.  ..|| 
rilvigDlHgglddle......d.lllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlkl
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 68-98 9.2e-07 21.3 In-house 99-129 (317) alignment 
Range on Protein: 68-98
Range on HMM: 99-129/317.0
STKKWVFLGDYVDRGYKSLDCICLVFSLKSL
. ||..|||||||||  |.. . |.|.|| |
gykkylflGdyvdrGpfsievvillfalkll
PPP_2 120-162 2.3e-06 20.4 In-house 155-197 (198) alignment 
Range on Protein: 120-162
Range on HMM: 155-197/198.0
DAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQM
| ..| ....|..|| ...|.. ...| ..  ...||.| |..
dpkekeellansarGagllfgpdvteelleknklkliiRaHev
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 4-52 4.9e-06 18.9 In-house 11-59 (339) alignment 
Range on Protein: 4-52
Range on HMM: 11-59/339.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNT
.  .||  |     ||   |  . ..  |. ..|||||||.||. .|. 
fcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldm