Gene F44B9.9 in Caenorhabditis elegans

Synonym: CELE_F44B9.9, F44B9.9

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP086_AA protein Get Run
CeleP086_AA_2-217 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045823 Metallo-dependent phosphatases 3-214 4.4e-53 173.7 In-house 42-327 (473) alignment
Range on Protein: 3-214
Range on HMM: 42-327/473.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCC
......|. |||...|..|||..| |.|......||||||..|| |||.  .  ..            . |||||.||||. ||....|...|| ..  .
llpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfpped...........rlvflGDlvDrGpdslevlelllalkikypgn

F-----------------------------------------------EN-VI--------------------------------DIILARTFWEDFDAP
.                                               .. ..                                |.  ... ..| |  
vfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPweddgdgl

AKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRK------LCTIFSAPRYMNEIDNSGAVMKVASNGkISISIMKNPNFA
 .  |..|..|| ...|.. ||.| ..  .. ||||||...| |.... |.|      ..|.|||| |... .| .||... ... ||. ...  .  
lrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphp

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 3-101 2.7e-51 167.6 In-house 5-103 (302) alignment
Range on Protein: 3-101
Range on HMM: 5-103/302.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
.|||.||..|...||||.||||||||||||||||||||||||||||.||.|.|.|.||.|..|.||..|.||||||||||.||..||||||.||.|.  
eysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 2-101 3.4e-51 167.2 In-house 5-104 (302) alignment
Range on Protein: 2-101
Range on HMM: 5-104/302.0
RTYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
..|||.||..|...||||.||||||||||||||||||||||||||||.||.|.|.|.||.|..|.||..|.||||||||||.||..||||||.||.|.  
keysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlypt





0049330 Metallo-dependent phosphatases 4-217 1.2e-47 155.7 In-house 30-305 (309) alignment
Range on Protein: 4-217
Range on HMM: 30-305/309.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
.|. ||. ||....|..|.|..| |.| .....||||||..|| |||.  .             .  . |||||.||||. ||....|...|| |.   .
lseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfp...........pedrlvflGDlvdrGpdslevlllllalkllypdnv

-----------------------------------------------EN------------------------VID----IILARTFWEDFDApaKPSFI
                                               ..                        ...     .|.   | | .     . .
fllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplp..iregf

RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNFAMKM
..|.|||.|.|.. ||.. .......||.|||.... |...|.|.||.|.||||.|.....| |||... ....||. ...  .. ...
apnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplllll

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 121-210 1.4e-47 155.4 In-house 210-299 (302) alignment
Range on Protein: 121-210
Range on HMM: 210-299/302.0
APAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
...||....|..|||||.||||||...|. ||..||||.|||.|.|||||||.||.|||||||||||.||.|||.||..|||.|||...|
vsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 122-211 2e-47 154.8 In-house 212-301 (302) alignment
Range on Protein: 122-211
Range on HMM: 212-301/302.0
PAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNP
..||....|..|||||.||||||...|. ||..||||.|||.|.|||||||.||.|||||||||||.||.|||.||..|||.|||...| 
sekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrnk

0053225 Metallo-dependent phosphatases 4-207 6.9e-44 143.6 In-house 22-287 (293) alignment
Range on Protein: 4-207
Range on HMM: 22-287/293.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC--
.|..||. ||....|..|||..| |.| .....|||||...|| .||.  .             .. . |||||.||||. ||....|...|| |.    
lseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfp...........pedrlvflGDlvdrGpdslevlelllalkllypdnv

---------------------CFENVIDIILARTFWEDFDA--------------------------------------------------PAKPSFIRN
                     ...  ..  | . ... ...                                                  |   | .  
vllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlwsgwlp

NKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISI
..|||.|.|.. || . ... .. ||.||||..| |.... |.||.|.||||.|... .| |||... .. .... .
syrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfkl

PP2Ac_SM00156 5-100 1.3e-27 89.6 In-house 2-86 (271) alignment
Range on Protein: 5-100
Range on HMM: 2-86/271.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLntrnssenaksKPIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
|| |.. ||. |.|..|.||.| |.|.|||.|||||||..||.|||           .    ....| ||||||||||..|. .|.|.|.|| |..
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll...........elageppeekyvFlGdYVDRGpqsiEvillLfalkilyp

PP2Ac_SM00156 114-210 2.4e-27 88.7 In-house 175-269 (271) alignment
Range on Protein: 114-210
Range on HMM: 175-269/271.0
TFWEDFdaPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
  |.|     | . ....|||||| |.|.||.|... .|..||.|.|.... |..||||.|| ||||||.|..| .|..||.|| .| |.||  .|.
llwsdp..eqkekgfqpskrglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 123-210 3.4e-27 88.3 In-house 187-274 (280) alignment
Range on Protein: 123-210
Range on HMM: 187-274/280.0
AKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
 | .   .| || || | .  |.. ...|.| ||.||||..  |..||||.|| |.||||.|..|.||| ||..| .. ..|. ..| 
nkvtgwaensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkp

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 125-210 4.5e-27 87.8 In-house 208-293 (298) alignment
Range on Protein: 125-210
Range on HMM: 208-293/298.0
PSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
 .   .|.|| || | | .|.. .  |.| |.||.||..  |..|||..|| ||||||.|... ||| ||||| .. ..|  ..| 
vkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkp

subfamily_PPP1C_pd Subfamily PPP1C 112-210 9.1e-25 80.4 In-house 182-278 (282) alignment
Range on Protein: 112-210
Range on HMM: 182-278/282.0
ARTFWEDFDAPakPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
.  .| | |       . .|.|| |. |.. .|.. ..  ...||||.||.. .|..|||.|.| |.|||| |..|.||.|||..| .. ..| .|.| 
cdllWsdpdke..vlgwsendrGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkp

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 110-209 2.1e-24 79.3 In-house 216-313 (317) alignment
Range on Protein: 110-209
Range on HMM: 216-313/317.0
ILARTFWEDFDApaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.||   | | ||  . .  .. .|| .  | ..||.| .. |.. |.||.||..  |..||||||| |||||| |  ..|| .||..|... ||||....
vladltwadpda..evkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvdkklkisinvlr





PPP_3 4-99 7.8e-24 77.1 In-house 2-86 (271) alignment
Range on Protein: 4-99
Range on HMM: 2-86/271.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.|..||  |.... |...||..| ||| |||..||||||..||..| ..  .|..           .|..|||||||||.|||....|...|| ..
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspe...........tkYlFlGdyVDrGkkslEvlllLlalkiky

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 115-213 1.2e-23 76.5 In-house 187-284 (287) alignment
Range on Protein: 115-213
Range on HMM: 187-284/287.0
FWEDFDAPaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNF
.| | .   . .|  |  |..|| | .  |.. .. |.|.|||| |..   |..|..|..| |.||||.|. |  | |||..|.   ..|.  .|  .|
lwadpekd.aktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedf

subfamily_PPP3C_pd Subfamily PPP3C 10-100 3e-23 75.3 In-house 47-126 (452) alignment
Range on Protein: 10-100
Range on HMM: 47-126/452.0
FCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNtrnssenakskpIYG-FSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
  ..... .|.|||||| |.. |.|..||||||| ||..|..            . |  .. |..|||||||||| |..|.  ...||  ..
lkiieeaakllkkektlleveaPitviGdihGqfydllklfe............vgGdPastkylflGdyvdrGyfsiecvlylyalkiayp

PPP_3 120-209 7.6e-23 73.9 In-house 181-270 (271) alignment
Range on Protein: 120-209
Range on HMM: 181-270/271.0
DAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
. |.| ....|.|||....| . ...| ..  ...||.| |.. ..|.....|.|. |.|||| |.....| ||..|.... . .. ...
sdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 111-210 3.3e-22 72.3 In-house 185-282 (284) alignment
Range on Protein: 111-210
Range on HMM: 185-282/284.0
LARTFWEDFDApaKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKN
.|   | | .|  . .  .. .||    | ..||.| ..  .. |.|| ||..  |..||||||| |||||| |  ..|| .||..|...  .|....|.
iadltwadpea..evegykesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp





subfamily_PPP1C_pd Subfamily PPP1C 5-100 4.8e-22 71.5 In-house 11-95 (282) alignment
Range on Protein: 5-100
Range on HMM: 11-95/282.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
...|.  ||..  |..... .| |.. ||.||||||||..||.||..| .. ...           ...||||||||| .||. |.|....|  ..
keaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpes...........nylflGdyvdrGkqsletivlllaykikyp

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 115-212 9.9e-22 70.5 In-house 200-295 (299) alignment
Range on Protein: 115-212
Range on HMM: 200-295/299.0
FWEDFDAPAKPsfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPN
.| | |   |    ..| ||.|  | .  |....  |.| |. | ||..  |..|||..|| |||||| |  ..||| |.|||  |   .. ..|  .
lwadpdqsvkd..wlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptp

PPP_1 5-99 1.3e-21 70.1 In-house 2-85 (264) alignment
Range on Protein: 5-99
Range on HMM: 2-85/264.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
...||. |.... ||..||..| |.| ..|..|||||||.||..| ..  .|..           ....|||||||||..|.....|...||  .
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspe...........tnYlFlGDyVDRGkdSvEilllLlalklky

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 4-103 2.5e-21 69.0 In-house 24-112 (298) alignment
Range on Protein: 4-103
Range on HMM: 24-112/298.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenaKSKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
 ...... |.... ..||| |.| |. .|... ||||||. ||.||..         . |     .. ..||||||||| ..|. |.|... |  . . |
ikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdk.......agfp....pdanylflGdyvdrGrqnlevivlllaykvkypnnf





subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 111-208 9.6e-21 67.2 In-house 179-274 (281) alignment
Range on Protein: 111-208
Range on HMM: 179-274/281.0
LARTFWEDFDAPAKpsFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIM
.   .| | |  ..    ..  || |  | .. |...|. |.. ||.|.||.. .|.. .. ||| |.||.| | .   |..||.||  . .||.  .
viDllwadpdnkve..ewkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislval

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 115-209 3.1e-20 65.4 In-house 193-287 (290) alignment
Range on Protein: 115-209
Range on HMM: 193-287/290.0
FWEDFDAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.| | .     ..  | .|..|| | . .... .. | .||||| |..   ||.|  |.|| |.|||| |  .  | ||...|.   ..|| ..|
lwadptrdkddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlk

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 5-98 2.8e-19 62.6 In-house 9-97 (284) alignment
Range on Protein: 5-98
Range on HMM: 9-97/284.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSS---ENAKSkpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSL
...||. |     ||| |||   ||  ||.||||||||||||. ||.        ..||.        ||..|||||||||  |.. | |.|..| |
kekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeake........kkylflgdyvdrgpfsievitllfaykll

subfamily_PPZ_pd Subfamily PPZ 124-204 4.9e-19 61.9 In-house 207-287 (300) alignment
Range on Protein: 124-204
Range on HMM: 207-287/300.0
KPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKIS
 .    .|.||.| |.|. |.|.    . . |..| | ..  |..|| || | |.|||| |  |.|| |||| |.     |
ssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcs

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 4-99 5.8e-19 61.4 In-house 8-92 (281) alignment
Range on Protein: 4-99
Range on HMM: 8-92/281.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskpiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
|.| |.  .. .|  .| .||.|.|| .|...|||.|.||.|| ||..  .             . ...|||||||||| .||... |.|.||  .
ytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrv...........peevlvflgdyvdrgpqslevlillftlkiry

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 3-100 6.8e-19 60.9 In-house 9-95 (287) alignment
Range on Protein: 3-100
Range on HMM: 9-95/287.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..| .... .|. . |...  ..| |.  |.|||||||||..||.|..|    . .            ...||||||||| |||. . |.|||| ...
afsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapk...........vqylflGdyvdrGakslevslllfslkiayp

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 115-214 1.8e-18 60.1 In-house 161-259 (263) alignment
Range on Protein: 115-214
Range on HMM: 161-259/263.0
FWEDFDAPAKpSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPNFA
.| | .  ||  |  |. | .|  | .  |.. |. |.| |||| ||..  |. |||||.| |.||| ||  |. |  ||. |    ..|.  .|  .| 
lwadpekdak.gfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedfe





PPP_1 121-197 2.6e-18 59.3 In-house 188-264 (264) alignment
Range on Protein: 121-197
Range on HMM: 188-264/264.0
APAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKV
 ... ....|..|| . .|.. .... ..  |..||.| |.. ..|..|...||. |||||. |..| .| ||..|.
dkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 129-209 4.5e-18 58.6 In-house 192-272 (284) alignment
Range on Protein: 129-209
Range on HMM: 192-272/284.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
  | ||.|  |   |. .    |.| |.|| ||..  |..|||.|.| |||||| |  ..||. ||| |  |   |. ...
npnsrgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlr

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 9-103 8.2e-18 57.7 In-house 28-111 (297) alignment
Range on Protein: 9-103
Range on HMM: 28-111/297.0
LFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
.. |||. ...||..|.. |.  |. ..||||||| ||.||.            |     | ...|||||||||  |.. | |... |  | . .
vlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrgg.......wp....ptanylflgdyvdrgrfsietivlllaykvkfpgnl

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 126-209 8.7e-18 57.6 In-house 210-293 (297) alignment
Range on Protein: 126-209
Range on HMM: 210-293/297.0
SFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
| . .|.||  . |   || . |  ... |..| ||..  |..||| ||| ||||||.|  ..||  |.| .  . . |. |..
sgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilr

subfamily_PPP6C_pd Subfamily PPP6C 5-99 1.2e-17 57.0 In-house 16-99 (290) alignment
Range on Protein: 5-99
Range on HMM: 16-99/290.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSsenakskpiygFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
....|  | |.|..|. .| ..  .| |||..||||||| ||. |..|  .           .  ...|||||.||||| ||. . ....||  .
pendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggq...........vpdtsyvflgdfvdrgyysletftrlltlkaky

PPP_2 33-99 1.4e-17 57.0 In-house 1-56 (198) alignment
Range on Protein: 33-99
Range on HMM: 1-56/198.0
VTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||..||.|||..||..| ..  .|..           .|..|||||||||.|||....|...||  .
vtvcGDlHGqldDLlilfknglpspe...........rkylFlGdyvDrGkkslEvlllllalklvy

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 110-209 1.9e-17 56.4 In-house 235-332 (339) alignment
Range on Protein: 110-209
Range on HMM: 235-332/339.0
ILARTFWEDFDAPAKPsfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMK
.|.   | | |   |    .   || |. |   |.    . |.. ...||||..  |..||  |.| |||||| |  . ||. ||. .  . |||| ...
vltdltwadpdptekg..ykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsidkklkisinvfr





subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 6-100 2.3e-17 56.0 In-house 8-91 (280) alignment
Range on Protein: 6-100
Range on HMM: 8-91/280.0
KTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRnssenakSKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..... ... . .... ..|. |.  ||...||.|||. ||.||..         | |      ....||||||||| . |. |.|... |  . 
eadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv.......sfp....pdqnylflgdyvdrgrqqlevillllaykvryp

PPP_4 33-99 5.9e-17 55.3 In-house 1-58 (197) alignment
Range on Protein: 33-99
Range on HMM: 1-58/197.0
VTIVGDIHGQFEDL-VRLLNtrNSSENA-KskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||.|||||||..|| ..||.  |. ... .         .. ||||||||||..||....|...||  .
vtvvGDiHGqlddlllkllk..ngglpsee.........rsyvflGDyVDRGkdslevlllLlalklvy

subfamily_PPP2C_pd Subfamily PPP2C 7-99 6.2e-17 54.7 In-house 20-101 (290) alignment
Range on Protein: 7-99
Range on HMM: 20-101/290.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.|.  | ... |...||. . |.. |||..||.|||| ||. |..   .| .            ...|||||||||| |.....|. .||  .
sevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspd...........tnylflgdyvdrgyysvetvtllvalkvry

PPP_5_Dcr2 33-99 1.5e-16 54.0 In-house 1-58 (199) alignment
Range on Protein: 33-99
Range on HMM: 1-58/199.0
VTIVGDIHGQFEDL-VRLLNTR-NSSEnakskpiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
||..||.|||..|| ..|...  . ||           ... ||||||||||..||....|...|| ..
vtvcGDlHGqlddlllilfkeggdpse...........erlyvFlGDyVDrGkdslevlllLlalklvy

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 10-103 2.5e-16 52.9 In-house 9-91 (284) alignment
Range on Protein: 10-103
Range on HMM: 9-91/284.0
FCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENAkskpiygfstkKWVFLGDYVDRGYKSLDCICLVFSLKSLFSCCF
 .||  ....|.|.  | |.  |. |.||||||| ||.||..       |           ...||||||||| . |. | |.|. | .|   |
etllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphra...........nylflgdyvdrgkhcletilllfaykvifpnhf

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 129-212 4.1e-16 52.3 In-house 193-276 (280) alignment
Range on Protein: 129-212
Range on HMM: 193-276/280.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIMKNPN
  . ||.|  | .. |...|. |.| ||.|.||..  |....| |.| |.|| | |  .. |. ||. . .| ..|.  .  | 
fhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlippp

subfamily_PPP4C_pd Subfamily PPP4C 7-98 5.3e-16 51.7 In-house 19-99 (288) alignment
Range on Protein: 7-98
Range on HMM: 19-99/288.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSENakskpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKSL
.|.  |   . |.. .|  . ..  |||. |||||||.||..|..   . ..           ....||||.||||. |.... |. .||  
eevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpe...........tnylflgdfvdrgfysvetfllllalkvr

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 5-99 6e-16 51.5 In-house 25-108 (299) alignment
Range on Protein: 5-99
Range on HMM: 25-108/299.0
SKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenakSKPiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
 . ||  | ..  . | .. .| |. .|. ..||||||. ||.|...  .        |       ...||||||||| . |. |.|..  |  .
keqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkag......fpp.....dvnflflgdyvdrgrqnlelitlllcfkiky

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 3-100 6.2e-16 51.2 In-house 15-101 (290) alignment
Range on Protein: 3-100
Range on HMM: 15-101/290.0
TYSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPiygfSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
..|  ... .|. . |...   .| |.  |..||||||||...|.| ..          .|       |..||||||||| |||.   |.| .| ..|
afsdkdileilekieeileplpalleveapivivgdihgqldallryfdavg.......yp....pkvkflflgdyvdrgakslevslllfcykirys

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 112-200 8.4e-16 51.0 In-house 195-281 (307) alignment
Range on Protein: 112-200
Range on HMM: 195-281/307.0
ARTFWEDFDaPAKPSfIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASN
   .| | | |.     .   ||  . |    ... |. | . ||.| |||   |.  .. ||| |||||| | |   |.|.|.||   
ndmlwadpd.psvfe.wkassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdet

subfamily_PPZ_pd Subfamily PPZ 9-99 1.3e-15 50.7 In-house 30-109 (300) alignment
Range on Protein: 9-99
Range on HMM: 30-109/300.0
LFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenAkskpiyGF-STKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
.. .     |||  . .| |.||.| ||||.|||. ||.||.        .      ||  . ...||||||||| .||. | |..  |  .
ilqicikarelflaqpallelspsvkivgdvhgqyadllrlftk......c......gfppsanylflgdyvdrgkqsletillllcykiky

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 4-106 6e-15 48.2 In-house 20-108 (307) alignment
Range on Protein: 4-106
Range on HMM: 20-108/307.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNssenaksKPIygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSlfsCCF
|.| |.  ..     .|  ||.| .| ||. .|||.||||.||. ..           .|        .|| |||||||  ||.|| |.|. |    |  
ytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillg.......rpp....etvyvftgdyvdrgllslecilllftyki...cyp

ENV
||.
eni

subfamily_PPG1_pd Subfamily PPG1 13-98 1.3e-14 47.1 In-house 23-97 (300) alignment
Range on Protein: 13-98
Range on HMM: 23-97/300.0
LDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakskPiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSL
 | . ||. ||  . ||  |||.|||.|||| |.. ...           |       ...|||||||||. |.. | |.  ||  
tdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqv......p.....dtnylflgdyvdrglysvetisllivlklr

subfamily_PPP5C_pd Subfamily PPP5C 122-205 1.9e-13 43.1 In-house 219-303 (322) alignment
Range on Protein: 122-205
Range on HMM: 219-303/322.0
PAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKV-ASNGKISI
| . . . . |||..| |     .. ..  |..||.| |..   |...  | || |.|||| | ....| ||.... ... |. .
pqeanGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkf

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 26-97 2.3e-13 43.4 In-house 2-62 (263) alignment
Range on Protein: 26-97
Range on HMM: 2-62/263.0
LAEISPPVTIVGDIHGQFEDLVRLLNTRNSSenakSKpiygfstKKWVFLGDYVDRGYKSLDCICLVFSLKS
| |.  |. |.|| |||..||.|..|.  ..    .|        ...||||||||| .||. | |.|||| 
llelqapinicgdthgqyndllrifnacgaa....tk.......tqylflgdyvdrgghslevimllfslkl

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 7-97 3.8e-13 42.5 In-house 9-88 (280) alignment
Range on Protein: 7-97
Range on HMM: 9-88/280.0
TELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTrnssenakskpIYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKS
 |. ... ||  .| .|  |.|   |. ..|||| |..|. ||..            |     .| .||||||||| . .. . |.| || 
heiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdl...........igrvpeeklmflgdyvdrgpqgievlillfclki

subfamily_PPPLV_pd Subfamily PPPLV 11-101 1.3e-12 40.6 In-house 4-87 (290) alignment
Range on Protein: 11-101
Range on HMM: 4-87/290.0
CLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLlntrnSSENAKSKPIygFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFSC
.| |. .. . .|. | |.  |. ..||.||...||. .     ..   .  ..  ..  . .|||||||||  |.. |. ...|| |.  
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyf.....ekvlwrtgvd..ltpasllflgdyvdrgdfsveliayllalkvlyps

subfamily_PPP4C_pd Subfamily PPP4C 129-208 1.3e-12 40.5 In-house 203-282 (288) alignment
Range on Protein: 129-208
Range on HMM: 203-282/288.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISISIM
    ||    | . .|.. ..  .|.||.| ||..  |.|.  ..|. |..||| |     |  |.... .. .   .|.
avsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif

subfamily_PPPLV_pd Subfamily PPPLV 126-204 1.9e-12 40.1 In-house 205-281 (290) alignment
Range on Protein: 126-204
Range on HMM: 205-281/290.0
SFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEiDNSGAVMKVaSNGKIS
 |. |..|| .  | |.|..   .  |.| ..| |..  .|...  . .| |.||. ||     |. |.. | .. |. 
GfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs.sneaalilv.dkkklr

subfamily_PPP6C_pd Subfamily PPP6C 129-206 5.2e-12 38.5 In-house 202-279 (290) alignment
Range on Protein: 129-206
Range on HMM: 202-279/290.0
RNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKISIS
   .||    | .  ..| ... |..||.| ||..  |.|.. | || |..||| |     |  .....  . . .  
avsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereak

subfamily_PPP5C_pd Subfamily PPP5C 10-100 8.4e-12 37.7 In-house 40-124 (322) alignment
Range on Protein: 10-100
Range on HMM: 40-124/322.0
FCLLDMVIELFKKEKTLAEISPP----VTIVGDIHGQFEDLVRLLNTRNSSEnaKskpiygfsTKKWVFLGDYVDRGYKSLDCICLVFSLKSLFS
. .| .. ||.||. .| ||. .    .|. ||||||| ||. ...   ..   .        .. ..| ||.||||  |...| .....| |. 
lkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlps..e........enpylfnGdfvdrGsfsveviltllgfkllyP

subfamily_PPP2C_pd Subfamily PPP2C 116-204 1.6e-11 36.9 In-house 194-279 (290) alignment
Range on Protein: 116-204
Range on HMM: 194-279/290.0
WEDFDapAKPSFiRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKIS
| | |   .  .    .||    | .   ..  .  ...||.| ||..  |...  ||...|||||| | .   | .|....  . | |
wsdpd..drggw.gisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkys

subfamily_PPP3C_pd Subfamily PPP3C 116-201 1.8e-11 36.5 In-house 221-313 (452) alignment
Range on Protein: 116-201
Range on HMM: 221-313/452.0
WEDFDAPA-KPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFAD------RKLCTIFSAPRYMNEIDNSGAVMKVASNG
 ||..  . . .| .|. || |. .. .|| |  .  ..  |.| |.   ||.. . .        | |.|||| |..  .| .||.|. .| 
ledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv

subfamily_PPP7C_pd Subfamily PPP7C 116-201 2.5e-11 35.9 In-house 242-325 (383) alignment
Range on Protein: 116-201
Range on HMM: 242-325/383.0
WEDfdAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNG
| |    ||     |  ||  . |     ..  .  |..|..| |.  | |..|  |.|. |||||  | .|  | || .|.... 
wsd..pkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdl

subfamily_PPP7C_pd Subfamily PPP7C 27-99 1.2e-10 33.6 In-house 60-122 (383) alignment
Range on Protein: 27-99
Range on HMM: 60-122/383.0
AEISPPVTIVGDIHGQFEDLVRLLNtRNSsenakskpiYGFSTKKWVFLGDYVDRGYKSLDCICLVFSLKSLF
. ||  ||. ||.||...||. .|  .|          .  . . .|| ||.|||| .|.. ......|  ..
taiskevtvcGdlhGklddlllily.knG.........lpseenpyvfnGdfvdrGkesveillillalllvy

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 4-53 2.8e-10 32.9 In-house 9-58 (317) alignment
Range on Protein: 4-53
Range on HMM: 9-58/317.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNTR
....||  |     ||| ||.   |.  |||||||||||||||. ||.  
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldln

subfamily_PPG1_pd Subfamily PPG1 121-203 1.2e-09 30.9 In-house 205-288 (300) alignment
Range on Protein: 121-203
Range on HMM: 205-288/300.0
APAKPS-FIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQMMPAGFKFFADRKLCTIFSAPRYMNEIDNSGAVMKVASNGKI
 | .   .... .||   .. .  |..  |  ..  |.| ||.   |.. . | ||.|..||| | .   |  ..... .. . 
hpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekder

Metallophos Calcineurin-like phosphoesterase 32-97 1.8e-09 31.2 Pfam-A 2-62 (200) alignment
Range on Protein: 32-97
Range on HMM: 2-62/200.0
PVTIVGDIHGQFEDLVrllntrNsSENAKSKPIYGFSTKKWVFLGDYVDRGYKSLDCICLV--FSLKS
.....||.||...||          ...  | .        .||||.||||  |. ...|.  ..|| 
rilvigDlHgglddle......d.lllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlkl

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 68-98 9.2e-07 21.3 In-house 99-129 (317) alignment
Range on Protein: 68-98
Range on HMM: 99-129/317.0
STKKWVFLGDYVDRGYKSLDCICLVFSLKSL
. ||..|||||||||  |.. . |.|.|| |
gykkylflGdyvdrGpfsievvillfalkll

PPP_2 120-162 2.3e-06 20.4 In-house 155-197 (198) alignment
Range on Protein: 120-162
Range on HMM: 155-197/198.0
DAPAKPSFIRNNKRGLSVCFNEAAVNETCRLLNISLIVRGHQM
| ..| ....|..|| ...|.. ...| ..  ...||.| |..
dpkekeellansarGagllfgpdvteelleknklkliiRaHev

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 4-52 4.9e-06 18.9 In-house 11-59 (339) alignment
Range on Protein: 4-52
Range on HMM: 11-59/339.0
YSKTELFCLLDMVIELFKKEKTLAEISPPVTIVGDIHGQFEDLVRLLNT
.  .||  |     ||   |  . ..  |. ..|||||||.||. .|. 
fcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldm