Synonym: CELE_F55A11.11, F55A11.11
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-STS-like_pd | Subfamily Cele-STS-like | 41-220 | 3.2e-72 | 233.6 | In-house | 2-204 (229) | alignment | ||
Range on Protein: 41-220
Range on HMM: 2-204/229.0
TVVMRSAERVDRVFGSaWLKSEKYMTKVNATDINVPKGAVLHPHFYHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---
.||.|||||||.|||. |.||....||....||||||........|...||.|.|||....|||||||.|||||.|.||||.||..||||...|..|
vvvirsaervdevfgk.WiksadletkyrpldinvPkelpkraksykldpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkglGlkr
ARILVEPGLLEpmewYRRAGAKQLPDFFDEALDFPqVDKTYKPI--FSMHEFTSMFGAKSQ-------EQCIQRIMLVV-----------------KNIC
|.| ||||||| ||.|....||......|..| ||..|||. .||.|..|.|.|..| ....|...||| ....
aaisvePgLle....yrkarevllppkafkklgyp.vdekYkPlkelsmaeslsdfvariqaafkkllskveqklilvvadnvsleltrredvesvddll
VIFRDTPAL
|....||||
vllkktpal
|
|||||||||
| subfamily_STS_pd | Subfamily STS | 40-235 | 4.6e-66 | 214.7 | In-house | 2-197 (245) | alignment | ||
Range on Protein: 40-235
Range on HMM: 2-197/245.0
VTVVMRSAERVDRVFGSaWLKSEKyMTKVNATDINVPKGAVLH---PHFYHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKST
.....|..||||.|||. ||||.. ..|....|.|.|| .. . .. |...||.|..|...|.|.||||...||.. .|||||.||..||||||.|..
tiyivRhgeRvdevfgk.Wlksfd.egkyerkdlnlpkelprrpdglkdyksDpPlterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl
G--ARILVEPGLLEPMEWYRRAgAKQLPDFFDEALDFPQVDKTYKPIFSMHEFTSmfgAKSQEQCIQRIMLVVKNICVIF-RDTPALIIGHAVTMDVASK
| ..| |||||||.....|.. ...|... . . |||.|..|||..|..|..| ..|.|....||. |||.|. . .|.. ||..||.|.|..|.
gkkikikvepgllewlkldrkp.ipellspeelkkffpqidedYkpvlslselks...keseeelyeRikkvvkeiiekvpedgniliVahaatldalsr
IG
ql
|
|||||||||
| 0048955 | Phosphoglycerate mutase-like | 80-232 | 1.3e-22 | 73.3 | In-house | 21-189 (240) | alignment | ||
Range on Protein: 80-232
Range on HMM: 21-189/240.0
VlhphfyHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEP-MEWYRRAGAKQLPDFFDEALDFPQVD
....|.| |. |. .|..|...|| . ....|| ||..|||..||. | .. |.|.| | . .. . ... . |.|.|. |
g......wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfgalegltldeiaekfpeelvlwlrd
KTYKPIFSMHEFTSM----------------FGAKSQEQCIQRIMLVVKNICVIF--RDTPALIIGHAVTMDVAS
. . ... .. .... |. | .....|.. ... .. . .. |...|. .. ..
pldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirall
|
|||||||||
| 0051064 | Phosphoglycerate mutase-like | 78-231 | 5.3e-22 | 71.4 | In-house | 24-191 (241) | alignment | ||
Range on Protein: 78-231
Range on HMM: 24-191/241.0
GavlhphfyHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEP-MEWYRRAGAKQLPDFFDEALDFPQ
| ....|.| |. |. .|..|...|| . ....|| ||..|||..||. | .. |.|.| | . .. . ... . |.|.|..
g........wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltleeiaekfpeelvawl
VDKTYKPIFSMHEFTSM----------------FGAKSQEQCIQRIMLVVKNICVI--FRDTPALIIGHAVTMDVA
|. . .. .. . . |. | .....|.. ... .. . . |...|. .. ..
rdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggviral
|
|||||||||
| 0043909 | Phosphoglycerate mutase-like | 86-230 | 8.7e-21 | 67.0 | In-house | 23-193 (249) | alignment | ||
Range on Protein: 86-230
Range on HMM: 23-193/249.0
YHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEP---------------------MEWYRRAGAKQL
....|.| |. |...|.||...|| . ....|| .|..|||..|.. | . |.|.| | . | ||
gwlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrErdfGalegltkaeiaekypeelvawlrrsydvlp
PDFFDEALDFPQVDKTYKPIFSMHEFTSMFGAKSQEQCIQRIMLVVKNICVI--FRDTPALIIGHAVTMDV
| . . . ... ...|. . .... . |. | .....|.. ...... ... ||..|. .. .
plleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHggvlra
|
|||||||||
| 0035570 | Phosphoglycerate mutase-like | 84-231 | 2.1e-20 | 65.6 | In-house | 17-148 (219) | alignment | ||
Range on Protein: 84-231
Range on HMM: 17-148/219.0
HFYHfNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIakstGARILVEPGLLEP-MEWYRRAGAKQLPDFFDEALDFPQVDKTYKPIf
... ..|.| |. |. .|.||...||.. ....|| ||..|||..| | . ..|.| | . .. ... ....|.|.. . |. . ..
rlqg.dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii....glpveidprLrEidfgdlegltldeiaekypeelaawlrdpydyrp.
smheftsmFGAKSQEQCIQRIMLVVKNIcviFRDTPALIIGHAVTMDVA
|. | .....|.. ... . .. . |...|. .. .
........pggEsladvvaRvlpaleel...edgenvlvVsHggviral
|
|||||||||
| 0036777 | Phosphoglycerate mutase-like | 85-230 | 6.4e-20 | 64.3 | In-house | 22-189 (247) | alignment | ||
Range on Protein: 85-230
Range on HMM: 22-189/247.0
FYHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEP--------------------MEWYRRAGAKQL
....|.| |. |...|..|...|. . ....|| ||..|||..|.. | .. |.|.| | . ...| .
qgwlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltkaeiaekypeelvawwrdpydyr
PDFFDEALDFPQVDKTYkpiFSMHEFTSMFGAKSQEQCIQRIMLVVKNICVI--FRDTPALIIGHAVTMDV
| ... | . ..| .. . ..... . |. | .....|.. ...... .. |...|. .. .
ppllelllelllldllr...yallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlra
|
|||||||||
| 0037864 | Phosphoglycerate mutase-like | 86-230 | 1.5e-19 | 62.8 | In-house | 28-169 (211) | alignment | ||
Range on Protein: 86-230
Range on HMM: 28-169/211.0
YHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEpmeW---Y-RRAGAKQLPDFFDEALDFPQVDKTY
....|.| |. |...|.||...|... ....|| ||..|||..|.. | .. |.|.| | . . ... ... |.|.. . |. .
gwldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrE...rdfgalegltleeiaekypeelvawlrdpyd
KPIfsmheftsmFGAKSQEQCIQRIMLVVKNICVIF--RDTPALIIGHAVTMDV
.. |. | .....|.. ...... . .. |...|. .. .
frp.........pggEsladvvaRvlpaleellarllkdgenvlvVsHggvlra
|
|||||||||
| 0036887 | Phosphoglycerate mutase-like | 85-231 | 7.2e-19 | 60.7 | In-house | 21-157 (202) | alignment | ||
Range on Protein: 85-231
Range on HMM: 21-157/202.0
FYHFNPPITNIGKYSAQLIGRALRnrGIEPGVIFCSPTLRTLQTAAAIAKSTGARILVEPGLLEPMEWYRragakqlpdffdEALDFPQVDKTYKP----
....|.| |. |. .|..|. |. . ....|| ||..|||..||. | . |.|.| | .. | | .... ..|
qgdldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaealglpvivdprlrEidfgal............egltleeiaekypeelaa
IFSMHEFTSMFGAKSQEQCIQRIMLVVKNICVIFRDTPALIIGHAVTMDVA
.. . .... |. | .....|.. ...... ... |...|. .. ..
wlrdpydfrppggEsladvvaRvlaaleellarldggnvlvVsHggvlral
|
|||||||||
| 0039931 | Phosphoglycerate mutase-like | 85-230 | 1.5e-18 | 59.5 | In-house | 18-147 (219) | alignment | ||
Range on Protein: 85-230
Range on HMM: 18-147/219.0
FYHfNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIakstGARILVEPGLLE-PMEWYRRAGAKQLPDFFDEALDFPQVDKTYKPIfs
... ..|.| |. |. .|..|...|... ....|| ||..|||..| | . ..|.| | . .. ... ....|.| . . |. . ..
lqg.dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii....glpveidprLrEidfgdlegltleeiaekypeelaawlrdpydyrp..
mheftsmFGAKSQEQCIQRIMLVVKNICVifrDTPALIIGHAVTMDV
|. | .....|.. ... .. . . |...|. .. .
.......pggEsladvvaRvlpaleella...genvlvVsHggvira
|
|||||||||
| 0049178 | Phosphoglycerate mutase-like | 86-230 | 1.5e-18 | 59.8 | In-house | 24-188 (243) | alignment | ||
Range on Protein: 86-230
Range on HMM: 24-188/243.0
YHFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTG---ARILVEPGLLEP---------------------MEWYRRAGAKQL
....| | |. |...|..|...|. . ....|| .|..|||..|.. .| .. |.|.| | |.|. .
gwtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdfGalegltkaeiaakypeelvawwrdpydarp
PDFFDEALDFPQVDKTYKPIFSmheftsMFGAKSQEQCIQRIMLVVKNICVI--FRDTPALIIGHAVTMDV
| .. | .| .| ..... . |. | .....|.. ...... .. |...| .. .
palllldlllplldrlladldl......lpggEsladvaaRvlpaleellaellhdgktvlvVaHggvira
|
|||||||||
| His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 90-229 | 1e-16 | 54.3 | Pfam-A | 24-156 (158) | alignment | ||
Range on Protein: 90-229
Range on HMM: 24-156/158.0
PPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTGARILVEPGLlepMEWYR----RAGAKQLPDFFDealdfpqvdKTYKPIFSMH
.|.|. |. |. .|..|.. .... ....|| .|..|||...... . .| ||.| |.. . ..... |. ..|. . . .
vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeldipiikeprL...rerdfgeweglpkeevkeefp.........eeyekwkrdk
EFTSMFGAKSQEQCIQRIMLVVKNICV-IFRDTPALIIGHAVTMD
.. .. .. | .....|. ..... ... ||..|. ...
kefrppegesladvyeRvapfleelieakdkgenvlivsHggvlr
|
|||||||||
| His_Phos_1 | Histidine phosphatase superfamily (branch 1) | 90-229 | 1e-16 | 54.3 | In-house | 24-156 (158) | alignment | ||
Range on Protein: 90-229
Range on HMM: 24-156/158.0
PPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTGARILVEPGLlepMEWYR----RAGAKQLPDFFDealdfpqvdKTYKPIFSMH
.|.|. |. |. .|..|.. .... ....|| .|..|||...... . .| ||.| |.. . ..... |. ..|. . . .
vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaeilleeldipiikeprL...rerdfgeweglpkeevkeefp.........eeyekwkrdk
EFTSMFGAKSQEQCIQRIMLVVKNICV-IFRDTPALIIGHAVTMD
.. .. .. | .....|. ..... ... ||..|. ...
kefrppegesladvyeRvapfleelieakdkgenvlivsHggvlr
|
|||||||||
| 0053607 | Phosphoglycerate mutase-like | 85-230 | 3.6e-16 | 51.8 | In-house | 20-149 (191) | alignment | ||
Range on Protein: 85-230
Range on HMM: 20-149/191.0
FYHfNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIakstGARILVEPGLLEPM-EWYRRAGAKQLPDFFDEALDFP--------Qvd
... ..|.| |. |......|...|... ....|| ||..|||..| | . |.|.| | .. ..| . . |.|
lqg.dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii....glpvevdprlrEidfgdwegltleelaekypeelaawlrdpldyrp..
ktykpifsmheftsmFGAKSQEQCIQRIMLVVKNICVifrDTPALIIGHAVTMDV
|. | .....|.. ...... . ..|...|. .. .
...............pggEsladvaaRvlpaleella...ggnvlvVaHggvira
|
|||||||||
| 0050036 | Phosphoglycerate mutase-like | 87-230 | 5e-12 | 38.0 | In-house | 22-139 (171) | alignment | ||
Range on Protein: 87-230
Range on HMM: 22-139/171.0
HFNPPITNIGKYSAQLIGRALrnrgiEPGVIFCSPTLRTLQTAAAIAkstgARILVEPGLLEP-MEWYRRAGAKQLP----DffdealdfpqvdktykpI
. ..|.| |. |. .|..| .. ....|| ||. |||..|. .. |.|.| | . . .... . .
wtdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil....lpvivdprLrErdfGawegltldeiaakype.................w
FSMHEFTSMFGAKSQEQCIQRIMLVVKNICvifrdTPALIIGHAVTMDV
. .. . . |. | .....|.. ...... . |...|. .. .
lldlldlappggEsladvlaRvlpaleell.....gnvlvvaHggvira
|
|||||||||
| subfamily_TFC7_pd | Subfamily TFC7 | 87-228 | 1.8e-08 | 25.3 | In-house | 28-170 (255) | alignment | ||
Range on Protein: 87-228
Range on HMM: 28-170/255.0
HFNPPITNIGKYSAQLIGRALRNRGIEPGVIFCSPTLRTLQTAAAIAKSTGARILVEPGLlepMEWYRRAGAKQLPDFF-DE--ALDFPQ-VDKTYKPIF
..|... | |. ... |.. ...| .||.|| | |.|. .||. . |. |. .|||. ... | . ||. ... |..
dsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeeleiPvyvdrGv...gewykpdrrPvilePasnevlskffPsvisldyestl
SMHEFtsmfgAKSQEQCIQRIM----LVVKNICVIFRDT-PALIIGHAVTM
| ...|. .|. ...... |.. . ||. || |.
tpsek.....geteeelyertkkfwpvfidrvekkfknvetilivthaatk
|
|||||||||
| 0053031 | Phosphoglycerate mutase-like | 37-150 | 1.5e-07 | 24.2 | In-house | 3-121 (342) | alignment | ||
Range on Protein: 37-150
Range on HMM: 3-121/342.0
LKKVTVVMRSAERVDrvfgsawlksekymtkvnatdINVPKGAVLHPHFYHFN-PPITNIGKYSAQLIGRALRNR---------GIEPGVIFCSPTLRTL
||.| |..| .| .. . .|. || .. .. |. |.. |. .||.||.| . ... |.. |||
LkqvivlvRHGaRtP.....................lskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtl
QTAAAIAKSTG----------------ARILVEPGLLEPM
|.|.|.... | .|| ...
qSAqaflaGlfppegtpilnpllgwqpipihtepessdal
|
|||||||||
| 0049226 | Phosphoglycerate mutase-like | 37-134 | 2.7e-06 | 20.0 | In-house | 3-89 (342) | alignment | ||
Range on Protein: 37-134
Range on HMM: 3-89/342.0
LKKVTVVMRSAERVDRVFGSAWLKSEKYmtkvnatdinvpkgavlhphfyhFN---PPITNIGKYSAQLIGRALRNR---------GIEPGVIFCSPTLR
||.| |..| ..| ..| . ..|.. .. .. |. |.. |. .||.||.| . .. |.. |
LkqvqvliRHGdRtPlakgpldflnewf.......................wgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdR
TLQTAAAIAK
|||.|.|...
tlqSaqafla
|
|||||||||
| subfamily_TIGAR_pd | Subfamily TIGAR | 87-137 | 7e-06 | 17.9 | In-house | 22-70 (222) | alignment | ||
Range on Protein: 87-137
Range on HMM: 22-70/222.0
HFNPPITNIGKYSAQLIGRALRNRGIEpgVIFCSPTLRTLQTAAAIAKSTG
. . |... | |..... | | .|. || |. ||. ||| .| |.
qtdtpLsekGveQakrvakrLsnekin..yifsSdllRAkqTaeiilkalk
|
|||||||||