Gene gsp-1 in Caenorhabditis elegans

Synonym: CELE_F29F11.6, gsp-1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP1C
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP105_AA protein Get Run
CeleP105_AA_5-304 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP1C_pd Subfamily PPP1C 22-301 4.3e-163 534.2 In-house 2-281 (282) alignment 
Range on Protein: 22-301
Range on HMM: 2-281/282.0
CRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLL
...|| |...||||.||..|.|||.||||||||||||.||.|||||||.|||||||..|.|||.|||||||||||||||||||.||||||.|||||.|||
skkgkevklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfll

RGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDR
|||||.||||||||||||||||.||||||||||.|||||.|||.||||.|.||||||.|...||||...||..||..|||||||||||||.|.||.||||
rGnhesasinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendr

GVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
|||||||.|||.|||...|||||.||||||||||||||||||||.||||||||||||||...||||.|..|||||||..|
GvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpakk
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 8-302 4.9e-139 455.5 In-house 2-297 (298) alignment 
Range on Protein: 8-302
Range on HMM: 2-297/298.0
NIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLL
..|.|....|.|         ...|...  |......|| .|. |.|..||.|.||||||||.||||||. .||||.|||||||||||||.|.||.|.||
evdellievlsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivll

LAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRF-SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLW
||||||||.|||||||||||..|||.||||.|||||. |..|...| | || ||..||| ..|.| |||||. |....|.|.. ||.| ... |  ||||
laykvkypnnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllw

SDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKK
.||.. |.|| || ||||..|| |||...|.. |.||..|||||| |||||||...|||.||||.|||.|||. ..|.||| |..||..|||..|.
adpenavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpekke
subfamily_PPZ_pd Subfamily PPZ 8-301 7.6e-138 452.0 In-house 2-296 (300) alignment 
Range on Protein: 8-301
Range on HMM: 2-296/300.0
NIDNLITRLLEVR-GCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICL
.||..| .||.    ..  | | . ..||  .|.|.||.||.|| ||||  ..|| ||.||||.||||||   |||| |||||||||||||||||||| |
dideiiqklldagyaakrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletill

LLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLW
||.||.|||||||||||||||| . |.||||||||||  ||.|||| | || ||.||..  |||| |||||| |..|..||.|.||||||| ||. ||||
llcykikypenffllrgnhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllw

SDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
|||      | .|.||||. .    . ||||.  .||.|||| |||||||||  | |||.|||||||||||| | .||| | |.|||..| | . 
sdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldplds
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 8-304 2e-132 434.0 In-house 2-299 (299) alignment 
Range on Protein: 8-304
Range on HMM: 2-299/299.0
NIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLL
..|.|...||.|         .. | |.. ||. ....|.||. |||.|||...|||||||| ||||.|.  ||||..|.||||||||||.| ||.|.||
dvdellskllnvgmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitll

LAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRF-SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLW
|..|.||||.||.||||||| .|||.||||.||..|. | .||  | |.|. .|.. ||  .|.| |||||| ||...|.| . || | |.  |  ||||
lcfkikyperffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllw

SDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK
.|||. | .|  | ||||. ||.||||. ..| |.||..||||||.|||||||...|||.|||| |||.|||.  .| ||| |.|.|..|||..|..|
adpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpkslk
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 30-301 6.6e-122 399.0 In-house 6-277 (280) alignment 
Range on Protein: 30-301
Range on HMM: 6-277/280.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
. ||.| .. .| ..|.. |  ..|..||...|||.||||.||||||.  .|||. ||||||||||||.| || |.|||||||.||.||..||||||..|
ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevis

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGP
||| |||.||.|||.| .|.. | . .. ||..||.  .|.| |||||..|. ........|| | .|  |  ||||.||...||||.|| ||||  || 
inrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvsvifga

DVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
.|| .. .. |.|||.| ||||.|||||||...|||.||||.|.|||||. ... ||| |. ||..|||. .
nvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpalr
0045823 Metallo-dependent phosphatases 25-303 3.5e-118 388.1 In-house 38-328 (473) alignment 
Range on Protein: 25-303
Range on HMM: 38-328/473.0
GKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGN
 |  ...| ... |... .||. ..| ||||.... ..||||||. |||||.|  ||||| ...||||.|||| .|||...||||.|.|||.|.||||||
kkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGN

HECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPdKDVTG--------W
||.. .| .|||.||. ......|.. | .....||.||.|..||...||||||||....|||.. || ..|| |||.|||||||  .. |        .
HElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.weddgdgllrlrff

GENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGGMMSVDETLmCSFQILKPSEKKA
| . ||....||||.| .||....||||.|.|..|..|||.. ...      ..|.||||||||...| .... .||.| .||....||. . 
gnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpl
0049330 Metallo-dependent phosphatases 6-304 1.3e-116 381.9 In-house 6-304 (309) alignment 
Range on Protein: 6-304
Range on HMM: 6-304/309.0
DLNIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETIC
.| ...||..||..   .. | ...|| |.. |..| .||..|.|.||||.... ..||||||. |||||.|  ||||| ...||||.|||| .|||...
pllllelilslldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevll

LLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLL
||||.|..||.|.||||||||.. .|..|||.||..|.....||. |.|....||.||.|..||.|.||||||||....|||...||...|..|||||||
lllalkllypdnvfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdll

WSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK
||||. .. |...|.||....||...| .||....||||.|.|..|..||..|....|.|.||||||||...|.|... .||.|..||....|.. . .
wsdplpiregfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpllll
PP2Ac_SM00156 30-299 1.3e-116 381.3 In-house 1-270 (271) alignment 
Range on Protein: 30-299
Range on HMM: 1-270/271.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
.|. |...|.....||. ... |.|..||. ..||||||..|||||.| .|.||| .|.|||||||||.||.|.|.||.|.|..|||...|||||||. |
lskeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsss

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGP
.|.||||..|.||. . .... |...|..||.|||.|.||.| ||||||.|.....||.. |. . |. |||.|||||||.... |.  . ||.|..||.
vnkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge

DVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
|.| .||....|.||.|||.||..||||||...|||.|||||||.||.|.. ...|...|..|.. ||. 
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
PPP_1 31-284 2.5e-114 374.0 In-house 2-263 (264) alignment 
Range on Protein: 31-284
Range on HMM: 2-263/264.0
SEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASI
.|.|...|..|..|.. ....|||.......|||||||..|||.||..||..|| |||||||||||||.|.|...||||.|.|||...||||||||....
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv

NRIYGFYDECK-RRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLL-------WSDPDKDVTGWGENDRG
...|||..|.. ...| ...||.||.|..||.||||||||...||||||.|. ..|||...| |.||..| |||||       .||.... ... ...||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG

VSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMS
....||.||..|||....|.||.|||.|.|.||||..||..||.|||.||. |..|.| ...
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
PPP_3 30-297 7.5e-114 372.3 In-house 2-270 (271) alignment 
Range on Protein: 30-297
Range on HMM: 2-270/271.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
.|| |.. |..| .||. ....|.|..||...|||||||..|||.||..||..|| .||||||||||||.|||...||||.|.|||....|||||||...
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

INRIYGFYDECK-RRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFG
||..|||..|.. .. . |..|.....|..||.|||||||....||||||......||..  |...||..|.|.|||.|..... .|.....||....||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg

PDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
|||...||....|.||.|||...|.|||.......||.|||||||....||| .....|.|...|..|.
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 30-298 1.9e-112 368.4 In-house 8-282 (284) alignment 
Range on Protein: 30-298
Range on HMM: 8-282/284.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFP------PEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRG
..| |.  ||...||.|  ... ||.|||.||.||||||..||| |..  |.|       | .|||||||||||  |.| | ||.|||...|.. |||||
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrg

NHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGV
|||   .|. |||| |||.|.| .|...|  .||..|..|....||.| |||.| || ...|. .. ||.|.|| |...|| |.||...|.|. | .|| 
nhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprga

SFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKP
  .||.. | .||....|||. |||||| ||||||| |.|||.|||| |||..||.. ...||| |..||..|||
gkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkp
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 33-304 4.6e-110 360.5 In-house 6-279 (284) alignment 
Range on Protein: 33-304
Range on HMM: 6-279/284.0
AEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINR
 .. .|  .. .||  ||.|.| ..|..||||||||. ||||||.  |||  ||||||||||||||. |||| ||.|||| .|. ||.|||||||. ||.
edvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslink

IYGFYDECKRRFSI-KLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTG-LLCDLLWSDPDKDVTGWGENDRGVSFTFGPD
|||||.||.||.    ....|   |  .|..||. ..|.| |||.|  |||. |.| . || | |.   |  |.||||| .   ||  | ||||. || |
iygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsd

VVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAK
 . |.|.| ..||. ||||||.|||||||.|.|||.|||| |||.||||  .| |.. |.||| .|.| .| |.
alrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkkiar
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 30-299 4.1e-108 354.1 In-house 23-295 (297) alignment 
Range on Protein: 30-299
Range on HMM: 23-295/297.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
..|  .  |   . ..| .|  ..|..||.|.|||||||. ||||||  ||.|| |||||||||||||. |.||| ||||||||.| |.|||||||||  
iteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecef

INRIYGFYDECKRRF-SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSP---DLQNMEQIRRVMRPTDVpDTGLLCDLLWSDPDKDVTGWGENDRGVSF
.|..||||.||..|. |.... .| | || ||.. || .||.| ||||||   .   .. .|.. |.|.    .|..||||.||   ..|. ||.||   
vnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqrgagc

TFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
 || | | |     .|||.|||||||.||||||| |.|||.|||| |||.|||.  .||.|| | |||.||.|.
gfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpt
0053225 Metallo-dependent phosphatases 13-299 1.9e-106 348.6 In-house 5-291 (293) alignment 
Range on Protein: 13-299
Range on HMM: 5-291/293.0
ITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKV
|..||..   .  . ...|| |.. |... .||....|.||||.... ..|||||.. |||.|.|. ||||| ...||||.|||| .|||...||||.|.
illlldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkl

KYPENFFLLRGNHECASINRIYGFYDECKRRF-SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDk
.||.|..|||||||.. .| .|||.||..|.. . .||. ..|....||.||||..||...|||||||| ...|||...||...|..|||.|||||||| 
lypdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.

DVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
...||. . ||....||...| .||....||||.|.|||| |||... ...|||.||||||.|...|.|... .|| |...|....|.
lwsgwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapv
subfamily_PPP4C_pd Subfamily PPP4C 29-298 4.6e-103 337.4 In-house 15-284 (288) alignment 
Range on Protein: 29-298
Range on HMM: 15-284/288.0
TMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECA
 ..| |..|||.|.|||.. .  . ....|  .|||||||..|||.||. ||  || |||||||.||||. |.||. ||||.||.||..  |.|||||. 
likeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr

SINRIYGFYDECKRRF-SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDkDVTGWGENDRGVSFTF
.| ..||||||| |.. |...|.  |. |. |..||.||.|||| ||||||.......|| . | ..||. | |||||||||. |..||.   ||  . |
qitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe.daegwavsprgagylf

GPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKP
| |||..| .. |..|||||||.| .|| .  .....|..||||||    |   .. .||.|   |.|.. 
gsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifea
subfamily_PPP2C_pd Subfamily PPP2C 29-302 1.3e-101 332.7 In-house 16-289 (290) alignment 
Range on Protein: 29-302
Range on HMM: 16-289/290.0
TMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECA
...|.|...||.| .||. ..  . |...|. .|||.|||. ||| ||  ||  |..||||||||||||  |.||..|| | ||.|.|   .||||||  
qleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhesr

SINRIYGFYDECKRRFS-IKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDkDVTGWGENDRGVSFTF
 | ..||||||| |...  ..|| ||| |..||..||.||.||| |||||| .. ...|| . |  .||. | |||||||||| | .|||  .||  .||
qitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgisprgagytf

GPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKK
| |.  || .. .| || ||||.| .||..  .|..||.|||||||    | .... .|..|  ||   .|. ..
gkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 28-300 1.2e-100 329.4 In-house 6-278 (281) alignment 
Range on Protein: 28-300
Range on HMM: 6-278/281.0
VTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHEC
| ... || .. .. . || ..  | |...| .. ||.|.|.||| ||||  | .||  ..|||||||||.||||.. ||...|..|... .||||||| 
vqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnhei

ASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTF
||.|.||||| ||. .. ..||  |  ||| |||.|||.... | ||||||.| .....|   .| . .| ||. ||||.|||..| .| .  ||.||||
asvnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftf

GPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE
| .|| .   | ...|| |||||| |||| .. |.|.|.||.||||  . ||. .. |||||  |.. | |. 
GknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpas
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 85-299 6.3e-97 317.5 In-house 101-315 (317) alignment 
Range on Protein: 85-299
Range on HMM: 101-315/317.0
ANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNME
 .|||||||||||  |.| . ||.|.|..||.. ||||||||  ..|. |||| |.|.|.| .|...|   ||.||..|....||.| |||.| .| ...
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMS
|. .. ||.|.|| |.|.|| |.|||..|.|. |  || .. ||.. | .||...||||. |||||||||||||| |.|||.||||.|||..||.. ..|
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDETLMCSFQILKPS
||. |..|...|.|.
vdkklkisinvlrpe
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 30-301 1.5e-95 312.4 In-house 10-284 (287) alignment 
Range on Protein: 30-301
Range on HMM: 10-284/287.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
.|. .|  . .| .||.   | |||.|||..|.||||||..||||.|.  | .|. .||||||||||| .||| . ||...|..||..  |||||||.  
fsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkk

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDT--GLLCDLLWSDPDKDVTGWGEND-RGVSFT
||..|||..| ||... .|.|.| | |. ||. | ....|.| |||.||.|. ..... . .||   .   ||  ||||.||.||  .   |  |..|  
inklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvv

FGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
||  .| ..|.. |.||| |||.|.|.||.|.....|||.|||| |.||  | | .. |...|  ||  ||| . 
fGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedf
subfamily_PPP6C_pd Subfamily PPP6C 30-297 1.5e-92 302.8 In-house 15-282 (290) alignment 
Range on Protein: 30-297
Range on HMM: 15-282/290.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
..|.....||..  ...| .  .  ...|. .|||||||. ||. ||  ||  |...|.||||.||||  ||||. .||. |.|||..  |||||||.  
lpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

INRIYGFYDECKRRFS-IKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPdKDVTGWGENDRGVSFTFG
| ..|||||||....   . || .|. |. |.|||.|||...| |||||||.. ..||| . | ...|  | .|||.|||| .||  |   .||  . ||
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edvetwavsprgagylfg

PDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
  |. .|..  .|.|||||||.||.|.... . .|||..||||||    |   .......   .....|
skvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfk
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 30-299 1.5e-88 289.9 In-house 6-275 (280) alignment 
Range on Protein: 30-299
Range on HMM: 6-275/280.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
|.  || |. .    ||. .  | | |||.|. |||| ||.|. |||.  |  || . .||||||||| | .| . ||.. |..| .  .|||||||  |
mtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetps

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGP
.|.||||| ||. .. . ||  |  ||| .|...|| ....| ||||||.| |.. || . || .  | ||| ||||||| .   ||  . ||.|. || 
vnkiygfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgk

DVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
 || .  .  ..||| ||||||.||||..| |.|.|.|| |||| .| ||  .. ..  |  ||| | | 
gvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlipp
subfamily_PPP3C_pd Subfamily PPP3C 30-290 9.5e-87 284.6 In-house 41-314 (452) alignment 
Range on Protein: 30-290
Range on HMM: 41-314/452.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
..|...  . ... ... ... |||.|||. ..||||||. |||.||| || | ...|||||||||||  |.|..  |.| |..||...|||||||||  
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrh

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWG------E-NDRG
.   . | .||| ..| .........|..||.|||.... .|.||||||.......|... |  ..| .|.||||||||| .|           . . ||
lteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvrG

VSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAK------RQLVTLFSAPNYCGEFDNAGGMMSVDETLM
 |. ..   |..||.. ||  | |||.. ..||. . |        |.||||||||.. ..| . .. ...  |
csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennvm
subfamily_PPG1_pd Subfamily PPG1 30-296 1.5e-83 273.5 In-house 14-293 (300) alignment 
Range on Protein: 30-296
Range on HMM: 14-293/300.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
. |. ...|..| .|.....  . |...|. . ||.|||. |.| .|. ||  |..||||||||||||  |.||| ||.. |..||    |||||||   
lpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrq

INRIYGFYDECKRRF--SIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPD---------KDVTG--W
| ..|||| || |..    ..|| .|. |. | .||.|||.|.| ||||||. . ..||. . |  .||. | |.|||||||.          |  |  .
itqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhf

GENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQIL
 . .||  ...| ||| |||.  |.. | ||||.. .||. .   .| |..||||||    |   .. . | .   |.. 
vvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvy
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 30-299 2.8e-83 272.3 In-house 16-289 (290) alignment 
Range on Protein: 30-299
Range on HMM: 16-289/290.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECAS
.|. .|  . .| .||.   | |||.|||. | |||||| ..||| |.  |.||. ..|||||||||| .|||   ||. ||..|...  |||||||.  
fsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrk

INRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTD--VPDTGLLCDLLWSDPDK--DVTGWGENDRGVSF
.||.|||..|  |. . .||| . | |. |.. | ...||.| |||.|....  | .. . .|      | ||  ||||.||..  | |   .  |..| 
vnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqraisv

TFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
 || ... ..|..  |.|| |||.| |.|..|  ...|||.|||| |.|.  | | .. | |.|  |. .||| 
vfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkpr
subfamily_PPP5C_pd Subfamily PPP5C 40-288 4.1e-83 272.0 In-house 44-298 (322) alignment 
Range on Protein: 40-288
Range on HMM: 44-298/322.0
HKSREIFLSQPILLELEAP----LKICGDIHGQYNDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIY
 ...|.. ..| |.|.. .    | .|||||||. ||| .||  | | |   ||| ||.||||  |.|.| .||..|. ||..||| |||||  ..|..|
leakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnkly

GFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGL-SPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKdVTGWGENDRGVSFTFGPDVVA
|| .|.| ... |. . ||. || ||.| .|.||.. .|||| | |  .....|.. | .. |. |||..||||||..  .| ..  |||...|||||  
GfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqe.anGrspskrGvgvqfGpdvtk

KFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV-DET
|||.  .|.|| |.|.| |.|||.  . .|.|.||||||| . .| |..... .. 
kflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgdd
PPP_2 60-250 8.5e-83 269.9 In-house 2-197 (198) alignment 
Range on Protein: 60-250
Range on HMM: 2-197/198.0
KICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECK-RRFSIKLWKTFTDCFNC
..|||.|||..|||.||..|...|| .||||||||||||.|||...||||.|..||....|||||||....|..|||..|.. .. . |..|.....|..
tvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfel

LPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLL----WSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQV
||.|||||||....|||||.......||..  |....|..|.|.|||    .|||... ... .. ||....|||||....|....|.||.|||.|
LplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
PPP_4 60-250 4.3e-79 258.1 In-house 2-196 (197) alignment 
Range on Protein: 60-250
Range on HMM: 2-196/197.0
KICGDIHGQYNDL-LRLFEYGGFPP-EANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFN
 ..||||||..|| |.|...||.|. | .|.||||||||||.|||...||||.|..||....|||||||..|.|..|||..|.... . ...|...|.|.
tvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvfd

CLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVP-DTGLLCDL-LWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQV
.||.|||||||....|||||..|.....|.|. |....| . ....|| ||||| .. .|. .. ||....|||||. |||....|.||.|.|..
llplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 32-296 9.2e-79 257.8 In-house 22-289 (307) alignment 
Range on Protein: 32-296
Range on HMM: 22-289/307.0
EAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASIN
  |.  . .... || |.  |.... |  . ||.|||.|||. .|   | |||. |.| |||||||  |||.| ||..||. ||||  ||||||| | .|
keefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvn

RIYGFYDECKR---RFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFG
. ||||.||     .   ..|  |  ||| |||.|||  ||.| |||||| |  ....|   .|   |  |.. |.||.|||  |  |    ||  ||||
kkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfg

PDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQIL
 .|.    .|  ..|| ||||.. |||  .. |.|.|.|||| ||  . ||| .. |||||      .
tnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvaf
PPP_5_Dcr2 60-251 3.3e-75 245.4 In-house 2-199 (199) alignment 
Range on Protein: 60-251
Range on HMM: 2-199/199.0
KICGDIHGQYNDL-LRLFEYGGFPP-EANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRR-FSIKLWKTFTDCF
 .|||.|||..|| |.||. ||.|. | .|.||||||||||.|||...||||.|..||....|||||||. ..|.||||..|....  . |..|...|.|
tvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdvf

NCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVP-DTGLLCDL-LWSDPDKDVTG-WGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVV
..||.|||||||....||||||.....|..... |....| ..|  .|| ||||| ....| . .. ||....|||||. |||....|.||.|.|...
dwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 52-300 7e-74 241.8 In-house 2-257 (263) alignment 
Range on Protein: 52-300
Range on HMM: 2-257/263.0
LLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSI-----
||||.||..|||| |||||||||.|.  |   ...||||||||||| .||| | ||.. |.  | ...|||||||  .||. |||. | |.||       
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

KLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDT-GLLCDLLWSDPDKDVTGWGEND-RGVSFTFGPDVVAKFLNRHDLDLI
 ... | . |. .|..|.. ..|.| |||.|| |.....|| .  | .   |  | |||||.||.||  |.  |  | .|  ||   |  . .| |.|||
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidli

CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSE
 ||||||| || ||| |.|.|.|||  |  |. |   .. |.. |  ||  ||| .
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkped
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 86-302 7.7e-74 241.8 In-house 121-337 (339) alignment 
Range on Protein: 86-302
Range on HMM: 121-337/339.0
NYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQ
 |||||||||||  |.| . || | |. ||.  .|||||||  |.|  |||| | . |.  .|.. | . || .|..|.|.. |.| |||.|  |  ..|
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq

IRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV
.  . || ..|| |.| || |.|||    |.    || || |||  .  ||.. ||... | |||||||||||  |.|||.||||||||. ||.  ..|.
fsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsi

DETLMCSFQILKPSEKK
|. |  | ....|  . 
dkklkisinvfrpesrd
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 30-298 1.6e-68 224.1 In-house 6-299 (302) alignment 
Range on Protein: 30-298
Range on HMM: 6-299/302.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPP-----------EANYLFLGDYVDRGKQSLETICLLLAYKVKYPENF
.|. |. .|...  | .  .  | |. .|. | ||||||..||.|.. .                .  ..|||||||||..|.| |||..|.|| ||.|.
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny

FLLRGNHECASINRIYGFYDECKRRFS----IKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRP-TDVPDTGLLCDLLWSDPD-KD
 |||||||. .||  ||| .| . |..     ..|. | ..|  .|.|||. |||.| |||.|| |. .|.|... || ..| .  |  |||..||   .
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq

-------VTGWGE-NDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKP
          . . . ||.|..|    | .. .| .|.|| ||||..  |. |||...|.|.||||.|  | || | .. ||     | ..|..
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 30-297 3.2e-68 223.1 In-house 7-299 (302) alignment 
Range on Protein: 30-297
Range on HMM: 7-299/302.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPP-----------EANYLFLGDYVDRGKQSLETICLLLAYKVKYPENF
.|. |. .|...  | .  .  | |. .|. | ||||||..||.|.. .                .  ..|||||||||..|.| |||..|.|| ||.|.
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny

FLLRGNHECASINRIYGFYDECKRRFS----IKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRP-TDVPDTGLLCDLLWSDPD-KD
 |||||||. .||  ||| .| . |..     ..|. | ..|  .|.|||. |||.| |||.|| |. .|.|... || ..| .  |  |||..||   .
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq

-------VTGWGE-NDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
          . . . ||.|..|    | .. .| .|.|| ||||..  |. |||...|.|.||||.|  | || | .. ||     | ..|.
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlr
subfamily_PPPLV_pd Subfamily PPPLV 36-286 2.7e-58 190.6 In-house 3-276 (290) alignment 
Range on Protein: 36-286
Range on HMM: 3-276/290.0
RALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLL----RLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASIN
 .||... .|....  ||||..|  . ||.||.|.||      |.  |     |..||||||||||. |.| |. ||| || ||  ..|||||||  |. 
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq

RIYGFYDECKRRFSIKL---WKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNM------EQIRRVMRpTDVPDTGLLCDLLWSDPDKDV---------
  . .. |.. .|  .|   |..|...|. ||.|| ||.|.||.|.|.    .        ..|   ..  |.  . |  |.|||||..|          
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlk.ddidgaplaldilwsdpaedrdlslrgelv

--TGWGEND-RGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGgMMSVD
   |. .|| || .  |. | . .||.| .|. . |||.| | |...  | .|.|.||. .|||  ..|  .. ||
lneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaa.lilvd
Metallophos Calcineurin-like phosphoesterase 59-250 1.4e-45 149.0 Pfam-A 3-198 (200) alignment 
Range on Protein: 59-250
Range on HMM: 3-198/200.0
LKICGDIHGQYNDL----LRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLL--LAYKVKYPENFFLLRGNHECASINRIYGFYDECK-----------
  ..||.||...||    |.|.. .. ..  ..|||||.||||. |.||..||  |..|...| ..||||||||. ..|  |||..|.            
ilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangee

-----------------------RRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIrrvmrptdvpdtgllcdllwsdpdkdvtgwge
                        .   . .  . ..|..||..||.| ||...||.||..... ..|                                
eyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi................................

ndrgVSFTFGPDVVAKFLNRHDLDLICRAHQV
     |. ||||.. |.|.....||..|.|. 
....gselfgpdalekllekygvdlvlrGHtH
subfamily_PPP7C_pd Subfamily PPP7C 59-191 3.8e-38 124.2 In-house 66-201 (383) alignment 
Range on Protein: 59-191
Range on HMM: 66-201/383.0
LKICGDIHGQYNDLLRLFEYGGFPP-EANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRF---SIKLWKTFTD
. .|||.||. .||| ..   |.|  | .|.| ||.|||||.|.| ...|||. . ||....| |||||   .|  |||  | . ..   . |. ... |
vtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlled

CFNCLPIAALIDEKIFCCHGGLSpDLQNMEQIRRVMR
 |  ||.|.||||||. .|||.| |  ..| . .. |
vfawlplatlidekilivhGGis.dktdlelldkier
subfamily_PPP7C_pd Subfamily PPP7C 201-297 3.5e-21 68.3 In-house 237-333 (383) alignment 
Range on Protein: 201-297
Range on HMM: 237-333/383.0
LCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
. |.||||| ..   . .  ||    ||||| .|.|....|.|. |.|.   .||||  .....|.||| ||  |  | |  . . ..|.  .   .
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyq
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 30-82 1.8e-18 59.8 In-house 9-61 (317) alignment 
Range on Protein: 30-82
Range on HMM: 9-61/317.0
MSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFP
..|.|.  ||...||.| ..|. ||||||..|.||||||..||| |..  |.|
fkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwp
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 31-82 1.3e-14 47.1 In-house 12-63 (339) alignment 
Range on Protein: 31-82
Range on HMM: 12-63/339.0
SEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFP
  ||.  |||..||.  |.||.|.||||. . ||||||..||| ...  |.|
caaelaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwp
subfamily_YNL217W_pd Subfamily YNL217W 60-178 6.8e-09 28.6 In-house 13-138 (235) alignment 
Range on Protein: 60-178
Range on HMM: 13-138/235.0
KICGDIHGQYNDLLRLFE--YGGFPPEANYLFLGDYVDRGKQSLETICLLlaykvkYPENFFLLRGNHECASINR------IYGFYDE--CKR-RFS-IK
 . ||.|| |..|..|..   ||  ...  ...|| ...| .|.|.. ..        ..   ..|||| . . .        |. .    ..  |   |
lvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllaykwvkkpkgaeplefsskfsflesk

LWKTFTDCFNCLPIA-ALIDEKIFCCHGGLSP
| |  ..    |. .  .  ....  |.||.|
lskadmeyarelgfsldipsdellvvhaGlvp