Synonym: CELE_Y40H4A.2, Y40H4A.2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPP1C_pd | Subfamily PPP1C | 42-309 | 3.7e-112 | 367.1 | In-house | 5-262 (282) | alignment | ||
Range on Protein: 42-309
Range on HMM: 5-262/282.0
QLRVDITISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRG
. .|... .||..|..|.....|.||.|||.. .|...|.|.||| .|||.| |..|||...|||||||||||.||. ...||...|..||...|||||
gkevklkeaeieallkkareillsqpillele.aPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrG
NHEDVNTTLNYGFYDECLEQWKNDegekVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaQPERNGWGL
|||..... ||||||| ...... .|..|.|.|||.||||.. |..|.|||.||.|.|||.|..|.||| || .||.|||||||| . |..||.
nhesasinriyGfydeckrrysik....lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdp.dkevlgwse
SHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYEGHKNNSSVL
..||.|||.||.|||.|..|||. |..|.||.... |. . .|...||| || |. .|....
ndrGvsftfgkdvvekflqkndldlivrahqvved....Gyeffakrqlvtvfsapnycgefdnagav
|
|||||||||
0045823 | Metallo-dependent phosphatases | 46-312 | 3.7e-90 | 295.8 | In-house | 42-312 (473) | alignment | ||
Range on Protein: 46-312
Range on HMM: 42-312/473.0
DITISEISQLTDKMKKAFLEQPALLEISNePITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHED
.. ... .| |..|. . ..| |||.| .|.|. | ||| |||.. .. ||.....||||.||||..|. |..||...| .||..|||||||||.
llpeedllklldeakeilkkepnllelsm.rivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHEl
VNTTLNYGFYDECLEQWkndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaqPERNG-------
. . |||.||.||. ||.....|.. ....|||||||||....|||.|| |..|..|..||||| .| .||..||||||| | .|
rllnglygfgdetleky....gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP..weddgdgllrlr
-WGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGR------LISLFSALNYEG-HKNNSSVLKLE
.| |.||.....|. .||||. ||.. |..|||. | | | |.|. .|..||| || | ..| ..||...
ffgnsprgagylFgpdaveeflkkngldlivrGHthvpe....GyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvid
|
|||||||||
PP2Ac_SM00156 | 49-311 | 3.2e-85 | 278.4 | In-house | 3-256 (271) | alignment | |||
Range on Protein: 49-311
Range on HMM: 3-256/271.0
ISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNT
.|. .| ...|. . ....|.|.| .|.||| |.||| |||.. ... ||..||.|||||||||.||. |..|||..| .||..|.|||||||. ..
keevlelleevkeilkqeknlvevs.apvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv
TLNYGFYDECLEQWkndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaQPERNGWGLSHRGISF
. |||..|. . |.... .| ..|...||||... |..| |||.|| ||||.||....|. | ||..||||||| . . .|. | ||.|.
nkiygfeeevkrky....gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdp.eqkekgfqpskrglsv
TYGKSVVEEFCAKNDIALVIRGHQLFKemypQGCVLRFGGRLISLFSALNYEGHK-NNSSVLKL
..|...|.||. ||.. |.||.|.. . .| ... ..|...||| ||... | .|||.
vFgedavkeflkknnlkliiRahevvd....eGyeffadkklvtifsapnycdefsnkaavlkv
|
|||||||||
0049330 | Metallo-dependent phosphatases | 47-307 | 1.2e-82 | 270.5 | In-house | 30-280 (309) | alignment | ||
Range on Protein: 47-307
Range on HMM: 30-280/309.0
ITISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
.. .|. .| .|.|. ....| |||.| .|.|. | ||| |||.. .. ||.....||||.||||..|. |..||...| .||..|||||||||.
lseeellllllkakeilksepnllels.mrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfllrGNHElr
NTTLNYGFYDECLEQWkndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaQPERNGWGLSHRGI
. . |||.||.|... |...|..|.|.....|||||||||..|.|||.|| | .|..|...|||| .| .|| |||||||| .|.|.|.. ..||.
llnglygfgdetlrky....gaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdp.lpiregfapnprgl
SFTYGKSVVEEFCAKNDIALVIRGHQLfkemYPQGCVLRFGGRLISLFSALNYEGHKNNSS
....| .||.|. ||.. |.||||.. ...|. |.|.||..||| || |. .|
gvvfghtaverflkkngldliirghga....vfgGyltffdgklitvfsapnycgrlgnlg
|
|||||||||
PPP_3 | 48-312 | 2.7e-81 | 265.5 | In-house | 3-259 (271) | alignment | |||
Range on Protein: 48-312
Range on HMM: 3-259/271.0
TISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVN
. .|. .|..|.|. . ... |.||| .|.||. |.||| ||..| . .|..||||||||||||..|. |..||...| .||..|.|||||||. .
senelkelvkklkeilekesnlveis.apvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
TTLNYGFYDECLeqwKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWGLSHRGIS
. |||..|.| |. |.||.... ..|...||||.| .||...|||.|| ..||..|...||. .|| |. .|||.|.... ...|.. |.||..
inkvYgFkkevl...kkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpe.keeglenskrGag
FTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYEGH-KNNSSVLKLE
...|..|.|||. ||.. |.|| |.| .| | . . |... .||| || .. .| ..||||
llFgpdvteefleknkLkliiRaHelkee....GyeilhdgkvvtvfSapnycerasnagailkle
|
|||||||||
0053225 | Metallo-dependent phosphatases | 47-306 | 3.3e-78 | 256.0 | In-house | 22-271 (293) | alignment | ||
Range on Protein: 47-306
Range on HMM: 22-271/293.0
ITISEISQLTDKMKKAFLEQPALLEISNePITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
.. .|. .| ...|. ....| |||.| .|.|. | ||. ||... . ||. ...||||.||||..|. |..||...| .||..|.|||||||.
lseeelllllleakeilkkepnllelsm.riyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvllrGNHElm
NTTLNYGFYDECLEQWKndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAqpERNGWGLSHRGI
. . |||.||.|... ....|....|.....||||.||||....|||.|| | .|..|..|.||| .| .|| .||||||| ...||. |.||.
llnglygfgdetlrkyg...aaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd..lwsgwlpsyrgl
SFTYGKSVVEEFCAKNDIALVIRGHQLfkemYPQGCVLRFGGRLISLFSALNYEGHKNNS
....| .|..|. ||.. |.|||||. .|.| |.|.|. .||| || |. .|
gvvfghtavlrflkkngldliirghqv....vpdgylpwfdgklvtvfsapnylgrlgnl
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 41-324 | 6.6e-78 | 254.8 | In-house | 18-290 (298) | alignment | ||
Range on Protein: 41-324
Range on HMM: 18-290/298.0
NQLRVDITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLR
..| |. .....| .. || | .|..|.|. . ||.| |.||| |||.| . ||.. |||||||||||.|.. |..||.. | .||...||||
kkltkvikeedveklielakkifkkqkslvev.dapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllr
GNHEDVNTTLNYGFYDECLEQWKNDEgekVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWG
|||| .||||.|| .. |. . .. | |.|| .||.|.|||...| |||.|. |.||.......|| . || ||||.||.. .||
GnheceainrvyGfyeeckrrykslr...lyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpen.avkgwa
LSHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNSSVLKleFVGQRVKVKQVL
..||.|...|. ||.... | || ||.|.||. .. | . . .|...||| .| |. .||. . | ....| ..
ensrGvsvvfGedvvkdllekldidlvvrahqvvqdGye....ffaekklvtifsaphycgqfdnsaavm..kvdeklvvsfev
|
|||||||||
PPP_1 | 50-307 | 3.3e-76 | 249.1 | In-house | 4-259 (264) | alignment | |||
Range on Protein: 50-307
Range on HMM: 4-259/264.0
SEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTT
.|. .| .|.|. . ... |||.| |.|||. |.||| ||..| . .|...|||||||||||..|| ...||...| .||...||||||||. . |
eelaelkkklkellnkeenllevs.eeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt
LNYGFYDECLeqwKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLL-------WSDPAQpERNGWGLS
|||..|.| |. ........ |.|...||||.| .|... |||.|| |..|..|. ..| .|| | .|||| .||. . ..... |
kvygFkkEvl...kkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddke.qeeavans
HRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYEGHKNNSS
.||.....||.|.|.|. ||.. |.|| |.. .| | . . ......||| || . .| .
iRGagylfgkdvtekflqknnlkliiRaHevkee....Gyeflkkrkvvtifsasnyyeegsnrg
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 46-306 | 3e-75 | 246.5 | In-house | 24-274 (300) | alignment | ||
Range on Protein: 46-306
Range on HMM: 24-274/300.0
DITISEISQLTDKMKKAFLEQPALLEISNePITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHED
. ||| |. | .. || ||||||.| .. .| |.||| |||.| || .||||||||||| ||. . ||.| | .||. .||||||||
clknseilqicikarelflaqpallelsp.svkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhec
VNTTLNYGFYDECleqwKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWGLSHRG
| | ||||||| | |.|. |.|||| .||||.. ||.|| |||.|| |.|...| . || || .|| |||||||.. | | ||
anvtrvygfydec....krrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptd.ssnewednerg
ISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNS
.|. | | ...| | . || | | . .. | . |...||| || | .|
vsycynkvainkflnkfgfdlvcrahmvvedgye....ffndrslvtvfsapnycgefdnw
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 47-309 | 5.5e-73 | 238.7 | In-house | 17-270 (290) | alignment | ||
Range on Protein: 47-309
Range on HMM: 17-270/290.0
ITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
.. ||. .|..|.|. . .. . |. . |.||. |.||| || .| |. .||||||||||| || ..|| ..| ||.. . .||||||
leesevkelcekakeilskesnvqev.kcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhesr
NTTLNYGFYDECLEQWKNdegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAqpERNGWGLSHRGI
. | |||||||| .. | .||..| | |...||.|.. ...|| |||.|| ...|..|....| || | |||||||| .|.|||.| ||
qitqvygfydeclrkygn...anvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd..drggwgisprga
SFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNN-SSVL
.|.|| . |.| .|.. |..| ||| | | . .....||| || | ...|
gytfgkdisekfnktngltliarahqlvmegyn....wshdrnvvtifsapnycyrcgnqaail
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 47-311 | 6e-73 | 238.4 | In-house | 6-261 (280) | alignment | ||
Range on Protein: 47-311
Range on HMM: 6-261/280.0
ITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
| .| .. .| || .. | ...|. . |..|. |.||| |||.| ||.|.|||||||||||.| . |..||.. | |||.. ..|||||| .
ikeadidrviekckkiltaqatmvev.dapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevi
NTTLNYGFYDECLEQwkndEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWGLSHRGI
. .|||.||. .. .... | . .. .||.|...|...| |||.|. | ||.|.. . ||. . || ||||.||.. . ||. . ||.
sinrkygfkdevkrr....yslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpen.kvtgwaensrgv
SFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNN-SSVLKL
| .|. || ... | || |..||||. .. | . . .|...||| .| |. .| ..||..
svifganvvkdltekldidliarghqvvqdgye....ffadkklvtvfsapkylgefdnsaavliv
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 47-312 | 1.7e-72 | 237.1 | In-house | 16-272 (288) | alignment | ||
Range on Protein: 47-312
Range on HMM: 16-272/288.0
ITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
|. .|. .| |... ..|. . .. . |.|| |.||| ||..| . |...||||||.|||| || . || ..| |||... |.|||||
ikeeevkalcakareilveesnvqrv.dspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr
NTTLNYGFYDECLEQWKNdegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAqpERNGWGLSHRGI
. | ||||||||... . .|||. . |. ..|||.| ||.|| |||.|| ...|..| ||.| || | |||||||| . .||..| ||
qitqvygfydeclrkygs...anvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe..daegwavsprga
SFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYEGHK-NNSSVLKLE
. .|..|||.|...||| |..| ||| | | |.| ......|| || | ...|.|.
gylfgsdvveqfneandielicrahqlvmegy....klhfnekvltvwsapnycyrcgnvaaileld
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 43-312 | 4.5e-71 | 232.4 | In-house | 4-264 (281) | alignment | ||
Range on Protein: 43-312
Range on HMM: 4-264/281.0
LRVDITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGN
.|..| || .. ... | |. || || ..||.|| |.|.| | |.| . .|.....||||||||| ||. |. |||..| ||.....|||||
hkvqytkeeienvireveaifseekaLvei.dkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgn
HEDVNTTLNYGFYDECLEqwknDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAqPERNGWGLS
|| . |||| || ||..| | || .|..| | .| |.|||.|| | .|... . .|. . || ||||.|| .. ..| |
heiasvnkiygfyvecvt....kyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpd.nkveewkas
HRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYE-GHKNNSSVLKLE
||.|||.||.||.. | . .. |.||.||. . | . | .||..||. || .|| ..|||..
srGssftfGknvvddvckrleveliirahqvvqd....Gyevlsgrklitvfsvpnycafyknaaavlkvd
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 43-308 | 4.8e-71 | 232.4 | In-house | 20-276 (299) | alignment | ||
Range on Protein: 43-308
Range on HMM: 20-276/299.0
LRVDITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGN
| . |. .| . |..|..|..|||. . || |. |.||| ||||| .. ||. ..|||||||||| | . ...||.|.| .||.. |.||||
ltksvkeqelqtlcavaksvfasqasllev.eapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgn
HEDVNTTLNYGFYDECLEQWKNdegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQPeRNGWGLS
|| ||||.|| ...| ..| .| |.|. |||. .||....| |||.|| |..|. . . || | | ||||.|| | .|
hecpainrvygfyeecnkryks...trlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqs.vkdwlan
HRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNSSV
||.|. .|. ||.. . . || || | ||. .. | . .|...||| | | .||.
vrgvsyvfgqdvvadvisrldidlvarahqvvqdgye....ffaskklvtifsaphycgqfdnsaa
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 49-309 | 8e-71 | 231.3 | In-house | 12-265 (287) | alignment | ||
Range on Protein: 49-309
Range on HMM: 12-265/287.0
ISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNT
..| .. .|... . |||||. .|||.| |.||| ||||| |.|. .|||||||||||..|. |. |||..| .||..| ||||||| .
dkdilevlekieeileplpalleve.apitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevkki
TLNYGFYDECLEQWKndegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPY--GLACDLLWSDPAQPeRNGWGL-SHRG
.|||..| . . |.... | | |. .|| | .. ...| |||||| |.||........| . || ||||.|| . .. | |.
nklyGfkeelkrkrq....erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd.aktfelnkira
ISFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYEGHKNNSSVL
|| .||..|.... | || |..| |.. .| | . | ||...||| | |.. | . .
isvvfGkkevddllkkldidlivrahevsee....Gyaflfdkrlvtvfsapyysgedtnlgav
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 50-311 | 5.6e-66 | 215.8 | In-house | 17-282 (300) | alignment | ||
Range on Protein: 50-311
Range on HMM: 17-282/300.0
SEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTT
. . .||||.|. .... . || |.||| |.||| .| || |. .||||||||||| || . || ..| ||| . ||||||| . |
vtvkeltdklkellvkesnvieir.spvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqit
LNYGFYDECLEQWKNDegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPA--------QPERNG--W
|||| |||... . .||. . . |. . |||.| ...| |||.|| |...|. ..| || | .||||||| .|.|.| .
qvygfyteclrkyggn..srvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhf
GLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYEGH-KNNSSVLKL
|.|| ..|||.|||.| .||. .|| ||| .| | . | ..| ...|| || | .|.|.|
vvsqrgagysygkdvvekflrnndmnriirahqlcnegy....qilfdnklstvwsapnycyrcgnkasilel
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 47-312 | 8.8e-66 | 215.0 | In-house | 15-271 (290) | alignment | ||
Range on Protein: 47-312
Range on HMM: 15-271/290.0
ITISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDV
.. ... .| |.... .||. .. .| |.||. |.||| |. .| | |...|.||||.|||| |. . .|...| .||... |||||||
lpendlkklcdlvldllleesnvqpvs.spvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesr
NTTLNYGFYDECLEQWKNDegeKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaqPERNGWGLSHRGI
. | ||||||||... | ..|. ... |. ...||.| ..|.| |||.|| .. |..|. ||| .| | |||.|||| . . | .| ||
qitqvygfydeclnkygna...nawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp..edvetwavsprga
SFTYGKSVVEEFCAKNDIALVIRGHQLFKEmypqGCVLRFGGRLISLFSALNYEGHK-NNSSVLKLE
. .|..|..||.. |.. |..| ||| .| | | .|....|| || | .|.|.||
gylfgskvtkefvhinnlklicrahqlvee....glkymfdeklvtvwsapnycyrcgnvasilale
|
|||||||||
PPP_5_Dcr2 | 77-273 | 1.4e-65 | 214.0 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 77-273
Range on HMM: 1-198/199.0
ITVVADMHGQSIHLLRIFLTNE-APP-NQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLEQWkndEGEKVWRMF
.||..|.||| || |.. . |. ...|.|||||||||..|. |..||...| .||..|.|||||||| .... |||..|.|... .|.|.....
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky...hgkkiykil
IDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVP-PYGLACDL-LWSDPAqPERNG-WGLSHRGISFTYGKSVVEEFCAKNDIALVIRGH
|.|...||||.| .||...|||.||...|.|... |||. ..| | .|| |||||. .. .| . | ||.....|..|.|.|. ||.. |.||.|
sdvfdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdpr.daqegcklnseRGagllfgpdvtekfleknnlkliirsh
QL
.|
el
|
|||||||||
PPP_4 | 77-273 | 3.5e-65 | 212.7 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 77-273
Range on HMM: 1-196/197.0
ITVVADMHGQSIHLLRIFLTNE-APP-NQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLEQwkndEGEKVWRMF
.||| |.||| || ..| | |. ...|.|||||||||..|. |..||...| .||..|.|||||||. ...| |||..|.||. .|.......
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek....hgkeilkkl
IDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVP-PYGLACDL-LWSDPAqPERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQ
|.|...||||.| .||...|||.|. ||||..|. |||. ..| ....|| |||||. .. .|. | ||.....|..|.|.|. ||.. |.||.|.
qdvfdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpr.eaqeglansvrGagllFgpdvtekfleknnlkliirshe
L
|
l
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 50-309 | 6.3e-65 | 212.1 | In-house | 19-272 (290) | alignment | ||
Range on Protein: 50-309
Range on HMM: 19-272/290.0
SEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTT
..| .. .|... . |||||. .||..| |.||| ||| | ||. |.||||||||||..|. | ||||.| ||...| ||||||| .
kdileilekieeileplpalleve.apivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhevrkvn
LNYGFYDECLEQwkndEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVP--PYGLACDLLWSDPAQPERNGWGLS-HRGI
|||..| . | ..|... | |. ..| | .| |..| |||||. .|| | ......| | || ||||.||.. . | .|.|
rlygfkeelark....rgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqrai
SFTYGKSVVEEFCAKNDIALVIRGHqlfkEMYPQGCVLRFGGRLISLFSALNYEGHKNNSSVL
| .||....... | . |..| | |. .| . | .|...||| | |.. | .
svvfgkkglddllkklalslivrah....evkeegfnflfdkklvtvfsapyysgndtnlgai
|
|||||||||
PPP_2 | 77-273 | 2e-64 | 209.9 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 77-273
Range on HMM: 1-197/198.0
ITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLeqwKNDEGEKVWRMFID
.||. |.||| ||..| . .|..||||||||||||..|. |..||...| .||..|.|||||||. . . |||..|.| |. |.||.... .
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevl...kkkggkkvykklqe
TFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLL----WSDPAQpERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQ
.|...||||.| .||...|||.|. ...|..|...||. ..| |. .||| .|||.. ..... |.||.....|..|.||.. ||.. |.|| |.
vfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpke.keellansarGagllfgpdvteelleknklkliiRaHe
L
.
v
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 49-322 | 3.4e-64 | 210.3 | In-house | 43-318 (452) | alignment | ||
Range on Protein: 49-322
Range on HMM: 43-318/452.0
ISEISQLTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNT
... .. .. | . ....|||.. ||||. |.||| . ||..| . | ..||||||||||||. |. .. |...| ||...||||||||
eeaalkiieeaakllkkektlleve.aPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhl
TLNYGFYDECLEQWkndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQPERNGW------GLS
| . | .|| .. .|.|. .....|...||||.. .. .| |||.|| ..||.||....| .| .|. ||||||||.. . |
teyftfkeeckiky....seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpns
HRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKE---MYPQGCVLRFGgRLISLFSALNYEGHKNN-SSVLKLEfvGQRVKVKQ
|| |. |. . | || |||. .|| |. .. || . .. | ||.|||| || . || ..|||.| . ....|
vrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfP.slitlfsapnyldvynnkaavlkye..nnvmnirq
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 50-309 | 6.9e-61 | 199.2 | In-house | 11-267 (284) | alignment | ||
Range on Protein: 50-309
Range on HMM: 11-267/284.0
SEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAP------PNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNH
|. .| . ...| ... ||| . |...| |.||| || .. | | ..|||||||||||| |. |. |||..| ..|..||||||||
kelielcyrarelfwkeklklei.eapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgnh
EDVNTTLNYGFYDECLEQWKndegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWGLSH
| .|||| || .. |... .| .||.|||.||.. |..| ||||| | .|.... .|||. .| |. .|| |.|| . | .|. |.
esrpvnmqygfyleckkrys....ealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpea.evegykesp
RGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNS-SVL
|| ..|.. |.||. | .. ||.| ||. .. | . .|...||| | |. .| .||
rgagkvfgakavkeflkkfkldlvvrahqvvmdgye....ffadrklvtifsapsycgqldniaavl
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 47-316 | 1.1e-59 | 195.1 | In-house | 6-291 (302) | alignment | ||
Range on Protein: 47-316
Range on HMM: 6-291/302.0
ITISEISQLTDKMKKAFLEQPALLEISNePITVVADMHGQSIHLLRIFLTNEAP-----------PNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQH
. ||. .| ... ... .. .| ||| |.|.| |.||| |.||.... ..|..||||||||||.|. .||.|..| ||..
ysksellllieaviellkkektlaeisp.PvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptn
VFLLRGNHEDVNTTLNYGFYDECLEQWKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLV-VPPYGLACDLLWSDPAQP
||||||| ||| .| .. . .| ..|. | ..| |||||..| |..| |||||| |||||||..|.||| | . || |||..||..
yillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldv
E-------RNGW-GLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQlfkeMYPQGCVLRFGGRLISLFSALNYEGHK-NNSSVLKLEFVGQ
. . . ||.|... .. |...| . .. |..|.|| | |.| . .|...||| .| |. .|||.. |.
qllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahq....miPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 102-309 | 1.3e-59 | 194.9 | In-house | 100-299 (317) | alignment | ||
Range on Protein: 102-309
Range on HMM: 100-299/317.0
NQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLEQWKndegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPW
..|||||||||||| |. |. |||..| .||..||||||||| . .|||| |. .... .... .| .||..||.||.. |..| |||||
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys....aalyeafqlafnvlplcavvnkkilcmhGGisee
LESLEDINSIERPLVVPPYGLACDLLWSDPAqPERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEG
| .|. .. ..||| .| |. .|| |.|| .| .|. | || .. .|.. |.||. | |. ||.|.||. .. | . . .|...||| .| |
lldlkqldklkrpldipdvGvladltwadpd.aevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGye....ffadrklvtifsapsycG
HKNNSS-VL
...| . ||
qldniaavl
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 47-316 | 1.7e-59 | 194.4 | In-house | 7-292 (302) | alignment | ||
Range on Protein: 47-316
Range on HMM: 7-292/302.0
ITISEISQLTDKMKKAFLEQPALLEISNePITVVADMHGQSIHLLRIFLTNEAP-----------PNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQH
. ||. .| ... ... .. .| ||| |.|.| |.||| |.||.... ..|..||||||||||.|. .||.|..| ||..
ysksellllieaviellkkektlaeisp.PvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptn
VFLLRGNHEDVNTTLNYGFYDECLEQWKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLV-VPPYGLACDLLWSDPAQP
||||||| ||| .| .. . .| ..|. | ..| |||||..| |..| |||||| |||||||..|.||| | . || |||..||..
yillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldv
E-------RNGW-GLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQlfkeMYPQGCVLRFGGRLISLFSALNYEGHK-NNSSVLKLEFVGQ
. . . ||.|... .. |...| . .. |..|.|| | |.| . .|...||| .| |. .|||.. |.
qllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahq....miPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 50-309 | 2e-59 | 194.3 | In-house | 9-259 (280) | alignment | ||
Range on Protein: 50-309
Range on HMM: 9-259/280.0
SEISQLTDKMKKAFLEQPALLEiSNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTT
|| . .. |.|. | | .. || |..|.| | . |.| |..| .||||||||| | . |. ||||.| || ....||||||| .
heiiaiirmveaifmeesnlce.aeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvn
LNYGFYDECleQWKNdeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPAQpERNGWGLSHRGISFT
|||| || |.| | .| | || ||....| .|.| |||.|| | |. | | || || |||||||.. . .|| | ||||.
kiygfyvec..qyky..gvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptn.kgegwfhsirgisym
YGKSVVEEFCAKNDIALVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYEGHKNNSSV-L
.|| |||. | .| |.||.||. .. | . | |||..|| || . |.. .
fgkgvveqacksleidliirahqvvqdgy....emmagrrlitvfsvpnycaqftnaaavv
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 54-320 | 5.2e-59 | 192.8 | In-house | 41-303 (322) | alignment | ||
Range on Protein: 54-320
Range on HMM: 41-303/322.0
QLTDKMKKAFLEQPALLEISN---EPITVVADMHGQSIHLLRIFLTNEAPP-NQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTT
.. ..|. . ..|.|.||.. . .|| |.||| || || | | .. ||| ||.||||| || |. .|...| ||.|.|| ||||| |
killeakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmn
LNYGFYDECLEQWKndegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPW-LESLEDINSIERPLVVPPYGLACDLLWSDPAqpERNGWGLSHRGISF
||| .|. .... ||| .| ..|| .||| || ||. |||. .|.|. |.| | || ..|||||| |.|| . |.||...
klyGfegevkakyt....ekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpq..eanGrspskrGvgv
TYGKSVVEEFCAKNDIALVIRGHqlfkEMYPQGCVLRFGGRLISLFSALNYEGHKNN-SSVLKLEFVGQRVKV
..| | ..|. .|.. |.|| | |. .| .. |.||..||| || ...| .....|. ...|.
qfGpdvtkkflkennleliirsh....evkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkf
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 55-328 | 3.4e-57 | 187.0 | In-house | 11-274 (284) | alignment | ||
Range on Protein: 55-328
Range on HMM: 11-274/284.0
LTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGF
| . . | .|| |.|. | || .. |.||| |||.| | | .||||||||||| . . . |||. | .|.|.|.|||||| |||
llfhafsifnkqpmliev.nspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygf
YDECLEQWKNdegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVP-PYGLACDLLWSDPAQPeRNGWGLSHRGISFTYGKS
|.|| .... |. | | |||.|..| ...| |||.| |. . .. .|.||. | | || |.|||||.. ..|| ||.|. .|
yeecqrrynk...psvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnf.qkgwnpnsrgvsyvfgsd
VVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNSSVLKleFVGQRVKVKQVLYRCR
. .. . .| ||.| ||. .. | . ||...||| | |. .|.. . .| . . . |. | |
alrklldrlqidlvvrahqvvqdgye....ffanrrlvtifsapfycgqfdnaaavm..yvnknlvcsfvvlrpr
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 45-312 | 5.2e-55 | 179.8 | In-house | 18-279 (307) | alignment | ||
Range on Protein: 45-312
Range on HMM: 18-279/307.0
VDITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHE
.. | |. .. . . | . ||..| . | || |.||| |. .|. ||. |.| ||||||| |. .. |||..| ||... |||||||
iqytkeefenviyeaqtifssekalvdi.dppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnhe
DVNTTLNYGFYDECLEQWKnDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVVPPYGLACDLLWSDPaQPERNGWGLSHR
. .||||.||. ||..| .| || .|..|.| |..| |||.|| | |... .|. | |. |.||.|| .| | | |
iarvnkkygfyeecvtsip.kcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadp.dpsvfewkassr
GISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYE-GHKNNSSVLKLE
| ||.| |... | . . |.|| ||. . | . | .||..||| | .|| |||..
gsgftfgtnviddvckrlgveliirahqmcfdgy....wvlsgrklitifsapmycnfyknagcvlkvd
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 68-303 | 6.1e-54 | 176.4 | In-house | 1-233 (263) | alignment | ||
Range on Protein: 68-303
Range on HMM: 1-233/263.0
ALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLEQWKNDE-
||||. . || .. | ||| ||||| . | . .||||||||||| .|. |. ||| .| |....||||||| ||||. | .... .|
allel.qapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreev
GEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDINSIERPLVV-PPYGLACDLLWSDPAQPERNGWGLSHRGISFTYGKSVVEEFCAKNDIA
| |. | . |. |||.|.. ...| |||||| |.||.|| .| || . |||||||.|| . . | || .|| |...| . ||
yesvynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldid
LVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYEGHK
|..| ||. . | . |||..||| |.
livrahqvveygy....affadrrlitvfsasryqiel
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 45-307 | 2.3e-50 | 164.6 | In-house | 21-276 (297) | alignment | ||
Range on Protein: 45-307
Range on HMM: 21-276/297.0
VDITISEISQLTDKMKKAFLEQPALLEIsNEPITVVADMHGQSIHLLRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHE
|| . .| | . | | ...|. | || |. |.||| |||.| || .||||||||||| |. . ||.. | ..| .||||||||
kviteervlklldlaldvfkaqksmvev.napikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhe
DVNTTLNYGFYDECLEQWKndeGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWL---ESLEDINSIERPLVvPPYGLACDLLWSDPAQpERNGWGL
||||.|| .... ... | | || .||. .| |..| |||.|| | .|. .. |||. .| .||||.|| |.
cefvnkvygfyeecqkryq...svrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierste.gkerlvadllwadpis.glsgfme
SHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYPqgcvLRFGGRLISLFSALNYEGHKNNSS
.|| .|. | . |.. .. || | ||. .. | . | .|...||| | |. .| .
nqrgagcgfgrdavlklcsefkldlvcrahqvvqdgye....ffagrklvtifsaphycgqfdnca
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subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 103-309 | 2.6e-48 | 157.8 | In-house | 120-317 (339) | alignment | ||
Range on Protein: 103-309
Range on HMM: 120-317/339.0
QKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECleQWKNDegEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWL
..||||||||||| |. |. || ..| ||....||||||| |||| | ... | ... | . || .|..||| ..| ||||| |
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrev..nyryd..aqlyecfqnmfnvfpfcavinntimcmhggisehl
ESLEDINSIERPLVVPPYGLACDLLWSDPaQPERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKEMYpqgcVLRFGGRLISLFSALNYEGH
|.... ..||| .| |. || |.|| .| .|. | || || .| . | | |. .||||||. .. | . | ||...||| || |.
tsfnqfsvfkrpleipdvgvltdltwadp.dptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgy....effdgrrlvtifsapnycgq
KNNSSVL
..|.. .
ndntaav
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Metallophos | Calcineurin-like phosphoesterase | 76-272 | 1.1e-40 | 133.1 | Pfam-A | 2-197 (200) | alignment | ||
Range on Protein: 76-272
Range on HMM: 2-197/200.0
PITVVADMHGQSIHL----LRIFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLL--FCMKHRYPQHVFLLRGNHEDVNTTLNYGFYDECLEQ--------
.|.|..|.||. .| |... .. .... .|||||.|||| | . .|| .. |...| .|||||||||. . . |||..|.|
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
----------------------WKNDEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLESLEDInsierplvvppyglacdllwsdpaqperngw
.. . | ...... ..|...||.| ..||....||..|. ..| .||
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
glshrgISFTYGKSVVEEFCAKNDIALVIRGHQ
|. .|. ..|... |... ||.|||.
......gselfgpdalekllekygvdlvlrGHt
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subfamily_PPPLV_pd | Subfamily PPPLV | 55-309 | 3.8e-40 | 131.0 | In-house | 5-273 (290) | alignment | ||
Range on Protein: 55-309
Range on HMM: 5-273/290.0
LTDKMKKAFLEQPALLEISnEPITVVADMHGQSIHLLR----IFLTNEAPPNQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTL
| |. . .... |||. |. |. |.||. | .. | ..|||||||||| || ... |. .| || .|.||||||| .
lcdvavdilaaeerllelk.sptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqe
NYGFYDECLEQWKNDEgEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWLE------SLEDI-NSIERPLVVPPygLACDLLWSDPAQPE--------
.. .. |. .. .. |.|| | ..|. .|||||| ||||.|.|| ...|| . .. .. | || |.||||||. .
sieykgegsfkfgdsl.eevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgap..laldilwsdpaedrdlslrgel
--RNGWGL-SHRGISFTYGKSVVEEFCAKNDIALVIRGHQLFKemypQGCVLRFGGRLISLFSALNYEGHKNNSSVL
.|. ..|| . ... .| | .|.. |.| |. . .| |. .|||. .||. .| | |.....
vlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevke....kGirlqqkgrlltvfsssrycGssneaali
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subfamily_PPP7C_pd | Subfamily PPP7C | 59-214 | 2.1e-35 | 115.1 | In-house | 45-202 (383) | alignment | ||
Range on Protein: 59-214
Range on HMM: 45-202/383.0
MKKAFLEQPALLEIS---NEPITVVADMHGQSIHLLRIFLTNEAPP-NQKYLFLGDYVDRGSQSVVVMCLLFCMKHRYPQHVFLLRGNHEDVNTTLNYGF
|| . . | . ..| . .|| |.||. || |. | | .. |.| ||.||||..|| ....|... ||..|.| |||||| | |||
akkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlryGf
YDECLEQWKNdEGEKVWRMFIDTFNCMPLAAVIGGKVFCAHGGISPWlESLEDINSIERP
| ...|. .|.|. |.. | | .|||..| |.. .||||| .|| ...|||
ikeveskykv.hgkkilrlledvfawlplatlidekilivhGGisdk.tdlelldkiers
|
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subfamily_PPP7C_pd | Subfamily PPP7C | 224-311 | 9.4e-09 | 27.4 | In-house | 238-321 (383) | alignment | ||
Range on Protein: 224-311
Range on HMM: 238-321/383.0
CDLLWSDPAQpERNGWGLSHRGISFTYGKSVVEEFCAKNDIALVIRGHqlfkEMYPQGCVLRFGGRLISLFSALNYEG-HKNNSSVLKL
|.||||| . .. . . || .| | ... .| .. |.|| | | |.| . .....||| || | . .||
ldilwsdpka.keGckpntlrGgGsyfGpdvtkkllqkynlkllirsh....eckpeGyefvhdkkvltifsasnyyeeGsnrGayvkl
|