Synonym: CELE_Y54F10BM.1, Y54F10BM.1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_PPM1D_pd | Subfamily PPM1D | 18-334 | 3.2e-134 | 439.9 | In-house | 1-308 (309) | alignment | ||
Range on Protein: 18-334
Range on HMM: 1-308/309.0
NMRITVAASQGGRRYMEDRCVIHTERINNGL-LDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSDEDILEAIRQGFLMTHEQMRHVYDEWPYT
....|..|.||||.||||...|..|. .... |...||.|||||||..|....|.||...|.|..|| |...||.|||||..||.|||.|.....|||.|
slsvtseadqGgrkymeDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkkleeWpkt
ASGYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVEN--GELHSRPLTTDHKPESVHEQLRIAKAGGETAVKSGVTRVVWKRPQkmsqfmmmtsnsne
.||..||||||.|.|.||. |||..|||||||.||. |. .|....||.||||||..|. ||...|||.|.||||.|||||||.
ksgllstaGttasvviirreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvvWkRpr..............
qKHHQNPQIMENIPFLSVARSLGDLWSYNEKTNMFIVSPEPDLGVHRLTGNDF-CLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEEINRNHSRCVLRS
..|..|.....||||.||||||||||||.|...|.||||||. |..|..|.. ...|||||..||.|...|.|.| ||||. |..|| .|.........
.lehngptvideiPFLavaRslGDlWsynaksgefvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvke
ALQKWRS--LRADNVTIATVIFD
|||.||| ||||||....||..
alqrwrskklraDnvsvivvile
|
|||||||||
| 0034914 | PP2C-like | 11-334 | 2.6e-51 | 167.2 | In-house | 13-291 (295) | alignment | ||
Range on Protein: 11-334
Range on HMM: 13-291/295.0
TPIQFGENMRITVAASQGGRRYMEDRCVIHTERIN--NgllDWTFVGVFDGHGGEHASEYVRRHLLMNITKN----QKFESNSDEDILEAIRQGFLMTHE
. . . ..|. || || |...||....... .. . |....|||||||| .|.|.....|. .. .. . . ..|.|||.||.|..|| ..|
llsslllllrvgvasdqGrrksneDavlvvlnllslle...dlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaade
QMRHVYDEWpytasGYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGtvENGelHSRPLTTDHKPESVHEQLRIAKAGgetavksgvtrV-------Vwk
.... .. . .. |||.....||..|||...|||| ..| || . ..||.|||| . |. || .||
ellelallr.....pelagsGtTavvalirgnklyvanvGDSravll..rng..elvqltvdhkpvnelererilsag...........gavshgrvn..
rpqkmsqfmmmtsnsneqkhhqnpqimeniPFLSVARSLGDLWSYNEKTN---MFIVSPEPDLGVHRLT-GNDFCLVLASDGMTNVMTGDQAISIVFK--
..| | |.||| . .. ... ..||.|||. |..|| ..| .|.|||||...|.. .....|| .
..............................gvlavtRalGdfdlklllslllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrsll
--EEEmveiheeiNRNHSRCVLRSALQkwrSLRADNVTIATVIFD
. . .. ... ||. ||.|. | ..
akgld........leeaaeeLvdlAla...rgsrDNiTvvvvrln
|
|||||||||
| PP2C | Protein phosphatase 2C | 22-305 | 1.5e-50 | 165.2 | Pfam-A | 4-241 (255) | alignment | ||
Range on Protein: 22-305
Range on HMM: 4-241/255.0
TVAASQGGRRYMEDRCVIHT-ERINNGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSdeDILEAIRQGFLMtHEQMRHVYdewPYTASgY
.. . || |. |||.... . ..| .. |..|||||||..|..| | || . ....|.. . .|.|..|| ...... . ...
gaselqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflele..kvekalrksfla.dtdeelks...skant.e
PSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENGElhsRPLTTDHKPESVHEQLRIAKAGGETAVksgVTRVVWKrpqkmsqfmmmtsnsneqkhhqn
||. |.| ....||. |||. .|||| . |.. | . ||.||||.. | || .|||. ..||...
psksGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngs.......................
pqimenipfLSVARSLGDLWSYNEKtnMFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEEINRN
|.|.|.|||....... ..||.|||. ...|| .| .|.|||||...|.. ..|...| .|.. . .|....
.........LavsRalGdfelkpke..eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaee
|
|||||||||
| PP2C | Protein phosphatase 2C | 22-305 | 1.5e-50 | 165.2 | In-house | 4-241 (255) | alignment | ||
Range on Protein: 22-305
Range on HMM: 4-241/255.0
TVAASQGGRRYMEDRCVIHT-ERINNGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSdeDILEAIRQGFLMtHEQMRHVYdewPYTASgY
.. . || |. |||.... . ..| .. |..|||||||..|..| | || . ....|.. . .|.|..|| ...... . ...
gaselqgarksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflele..kvekalrksfla.dtdeelks...skant.e
PSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENGElhsRPLTTDHKPESVHEQLRIAKAGGETAVksgVTRVVWKrpqkmsqfmmmtsnsneqkhhqn
||. |.| ....||. |||. .|||| . |.. | . ||.||||.. | || .|||. ..||...
psksGstavvalirgkklyvAnvGDSravLcrkdnak...keltedHkpsdedEreRIeeaggsvsn...ngrvngs.......................
pqimenipfLSVARSLGDLWSYNEKtnMFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEEINRN
|.|.|.|||....... ..||.|||. ...|| .| .|.|||||...|.. ..|...| .|.. . .|....
.........LavsRalGdfelkpke..eqlvsaePdvtsvklteedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaee
|
|||||||||
| PP2Cc_SM00332 | 20-331 | 1.6e-50 | 165.0 | In-house | 11-274 (274) | alignment | |||
Range on Protein: 20-331
Range on HMM: 11-274/274.0
RITVAASQGGRRYMEDRCVIHTERInnGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNS-DEDILEAIRQGFLMTHEQMRHVYDEWPYTAs
. ....|| |. |||..|.... ||.|.||||||||. ....|...| .. .. |.... ..|. ||....|| |.|.... .. .
sygkssmqgwrksmeDahvvvvdlv..eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelen.
gypSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENgelhSRPLTTDHKPESVHEQLRIAKAGGetavksgvtrvvwkrpqkmsqfmmmtsnsneqkhh
...|.|..........|| .|||| ..|.. .. ...|..||||| | || ||||
...alsGstavvallkkedlyvanvGDSravlcrngk....avqlsvdhkpedederkRikkagg...................................
Q---NpqimENIPFLSVARSLGDLWSY-NEKTNMFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEE--EMVEIHEEINRNHSRCVLR
. . |.| |..|| . |.| . ....||| |..|| .| .|.||||| ..|.. .....|| | . . . .|. . ....|
vvekg....rvngglavsrafGdhflkknkklkepyitaepdvkvvtltsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeair
SalqkwrSLRADNVTIATV
. .||.|. .|
r......ggseDniTvvvv
|
|||||||||
| PPM_PTC7 | 22-301 | 5.5e-50 | 163.2 | In-house | 4-241 (259) | alignment | |||
Range on Protein: 22-301
Range on HMM: 4-241/259.0
TVAASQGGRRYMEDRCVIHT-ERINNGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSdeDILEAIRQGFLMTHEQMRHVYdewPYTASgY
. | || |. |||.... . ..| .. |..||||||| .|..|.| || . ... ||. . .|.| .|| . ... . ...
gasafqgfrksmedahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeele..klekalrksflaldtdeelks...seant.e
PSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENGElhsRPLTTDHKPESVHEQLRIAKAGGETAVKsGVTRVVWKrpqkmsqfmmmtsnsneqkhhqn
||| |.| ....|.. |||. .|||| . |.. .| .||.||||.. | || .|||. . |..||...
pstsGstAvvalitgsklyvAnvGDSravLcrsgnav...kqltedHkpsnedEreRiegaggsvsnv.gngrvngv.......................
pqimenipfLSVARSLGDLWSYNEKTNMFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEMVeIHEE
| |.|..||..... .| . ||.||| .. .. .| .|.||||| ..|.. ..|...| .|.. .|
.........lavsRafGdfelkpketeeqlvsaePdisstkideedefliLasdGlwdvvsdqeavdlvrselskk.dpme
|
|||||||||
| subfamily_PPM1A_pd | Subfamily PPM1A | 16-334 | 5.8e-48 | 156.7 | In-house | 9-281 (282) | alignment | ||
Range on Protein: 16-334
Range on HMM: 9-281/282.0
GENMRITVAASQGGRRYMEDRCVIHTErINnGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKF-----ESNSDEDILEAIRQGFLMTHEQMRHVY
|...|..|.. || |. |||. .. .. .. .| ||.| |||||.|.....|| .||| ||...... |........||.||||| ..|..|.
gnglrygvssmqgwrvemEDahtvvas.lg.alkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairels
DEWPYTA-SgypstaGTTVSCVFIRNGKLYTGHVGDSAIFLgtVENGELHSrpLTTDHKPESVHEQLRIAKAGGETAvksgVTRVVWKrpqkmsqfmmmt
.. . | |.|. .|.... .|.. ..||| ..| ..||. . ||.||||.. .|. || .|||. | || .
tdlktadks......GsTavtvlvsekhliianlGDsRavl..crngkaaf..lteDHkpsrpkEkkRieqAGGsvv....vsRvnGa............
snsneqkhhqnpqimenipfLSVARSLGDLwSYNE----KTNMFIVSPEPDL-GVHRLTGNDfCLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEEInr
| |.|.||| .|.| |.. ||.||. ..| . .| ||||.||. |.. ......| |. |. . ||.
....................LAvsRalGDy.eykeeeekkaeeqlvsaepevtsierseedd.flvlacDGiwDvlsdeevvelvrkrlevadeleev..
nhSRCVLRSALQKWRslrADNVTIATVIFD
.. ... ||.| ||... |.|.
..akalvdkalekgs...rDNlsvlvvlfa
|
|||||||||
| 0049733 | PP2C-like | 19-333 | 7.1e-38 | 123.3 | In-house | 3-233 (235) | alignment | ||
Range on Protein: 19-333
Range on HMM: 3-233/235.0
MRITVAASQGG-RRYMEDRCVIhterinngllDWTFVGVFDGHGGEHASEYVRRHLLMNITknQKFESNSDEDILEAIRQGFLMTHEQMRHVYDEWPyta
... .| .| |...||.... ......|.||||| .|.|.....|. .. . ... . .|..||.|. ||...|.... . ..|
lsvgaasdigrvrkvneDavlv..........glllfavaDGhgghaagevasellvetll..elllelllldleealrkaflaaneallelalasp...
sgYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTveNGElhSRPLTTDHKPESVHEQLRIAKAGGETavksgvtrvvwkrpqkmsqfmmmtsnsneqkh
.. |||........||||. .|||| ..| . .|. ..||.||.| |. || .|||
..elagmgtTavvalldggklyvanvGDsrayllr..dgk..lvqltedhspvnelerqriitaggav................................
hqnpqimENIPFLSVARSLGDLWSYnektnmfivspePDLGVHRLTGNDfCLVLASDGMTNVMTGDQAISIVFKeeemveiheeIN-RNHSRCVLRSALQ
.. | . |.||||. ||. |..|. .| .|.|||||...|.. ....... . . .. ..... ||.
.......rvpgrlaltralGdlllk............pdvtvlelepgd.flllasDGlwdvlsdeeivdllrs..........ldleeaaerlvelala
KWRSlraDNVTIATVIF
.. ||.|. | .
rggr...DNiTvvvvrl
|
|||||||||
| subfamily_PPM1G2_pd | Subfamily PPM1G2 | 5-333 | 5.6e-34 | 110.4 | In-house | 3-286 (287) | alignment | ||
Range on Protein: 5-333
Range on HMM: 3-286/287.0
SEPMARTPIQFGENMRITVAA--SQGGRRYMEDRCVIHTERIN-NGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFEsnsDEDILEAIRQGFLM
|||. . ..|. ..|.. || |. ||| ....| .. . . ....|||||||.....|. ..| |.|...|. .. . ......||
sepvvakesascanaltkvgssamqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfk...egaleqilkdafle
THEQMRHVydewpytASGYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENgelhSRPLTTDHKPESVHEQLRIAKAGGETAVKSGVTRVVWKRpqK
| |.... . ..||.| | |.. ||| . .||| | . | .. |. ||||.. .|. || .||| ... . |
tDeellkd.......eklkdesaGstavvvlikeeklyvanaGDsravlsskgn....vkalsfDhkPqeesekkriiaagGfvelnrvngnLalsr..a
MSQFMMMTSNSneqkhhqnpqimenipflsvarslgdlwsynEKTNMFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEE
.. |. .... | . || .||. |..|. .| |||| ||. .|.| .. . .| .. . .|
lgDfefkknvk...............................kkpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgaklde
INRN-HSRCVLRSAlqKWRSLRADNVTIATVIF
| .. ..|. ... . .. .||.|. |..
iieelldkclapds..sntgvGcDnmtvvivvl
|
|||||||||
| subfamily_PPM1E_pd | Subfamily PPM1E | 19-194 | 4e-26 | 84.8 | In-house | 4-167 (265) | alignment | ||
Range on Protein: 19-194
Range on HMM: 4-167/265.0
MRITVAASQGGRRYMEDRCVIHTErIN-----NGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSDedilEAIRQGFLMTHEQMRHvydew
.....|| .. || ||||.|. . .| .. . .| .||||||| .|..| .|| .. ...|..... ||....| .| |.. .
yevsiaavknkrrkmEDrhvaled.lnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa....ealkeafkltDerflq.....
pyTASGYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLgtVENGELhsRPLTTDHKPESVHEQLRIAKAGGETAVKsGVTRV
.| ..|.| .|.|.. .|| . .||| .| |..|| . |.. |||| |. ||..||| | |. ||
..kaereklksGstavvvliekdqlyvaWlGDsqall..vrkgea..vqlmkpHkPeredEkkRieeagGlvvvi.gawRv
|
|||||||||
| subfamily_PPM1L_pd | Subfamily PPM1L | 20-194 | 1.5e-23 | 76.4 | In-house | 6-172 (269) | alignment | ||
Range on Protein: 20-194
Range on HMM: 6-172/269.0
RITVAASQGGRRYMEDRCVIHTERINNglLDWTFVGVFDGHGGEHASEYVRRHLLMNITkNQKFESNSDEDILEAIRQGFLMTHEQMRhVYDEWPYTASG
...| . .| | |||| |... |. . .|..|||||||| |.|... | .| |. | ..| . | | . |.|.| . | . .|
qvavysvlGrrprmedrfeieediknk..tgesffavfdGhGGefaaefakdvlvkaik.nklieldadkentepinfsklltdeils.vdekllekakr
YPSTAGTTVSCVFIRNGKLYTGHVGDSAiflGTVENGELHSRPLTTDHKPESVHEQLRIAKAGGETAVKsGVTRV
.||||. .... .| |||| | . . . .. ||. ||||. |.|. || |||| | . || ||
aediaGttalialvqesdlivanvGdsr...GvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafr.Gvwrv
|
|||||||||
| PPM_PTC7_SpoIIE | 23-294 | 2.5e-21 | 69.5 | In-house | 5-210 (230) | alignment | |||
Range on Protein: 23-294
Range on HMM: 5-210/230.0
VAASQGGRRYMEDRCVIHT-ERINNGLLDWTFVGVFDGHGGEHasEYVRRHLLmNITKNQKFESNSdeDILEAIRQGFLMTHEQMRHVydewpytasgyP
. | || |. |||.... . ..| . .||..||||| .....| .. ....|.. . . |..| ..| . .... |
asaaqgarksmedahispansekssggrlalvvgdvdGhGgra..alamgllr.talrelafagle..kpeeilrrlnlalaadlede...........p
STAGTTVSCVFIRNGK--LYTGHVGDSAIFLGTVeNGElhsrplttdhkpesvhEQLRIaKAGGETAvK-SGVTRVVWKrpqkmsqfmmmtsnsneqkhh
|. |.|.... |.. . ||. ..||| ..| . .| | || .||| . .||...
sssgaTavvalidpstgklyvanaGdsppllvrd.dgg................ereri.vagglps.lGilpgrvfgv.....................
qnpqimenipfLSVARSLGDLWSYNektNMFIVSPEPDlGVHRLT-GNDFCLVLASDGMTNVMTGDQAISIVFKEEE
|.|... |||. . ..|..||| .. .. |.| |.||||| ..|.. ......| .|.|
...........lavslapGdlllly...tDGvveaepd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdele
|
|||||||||
| subfamily_ILKAP_pd | Subfamily ILKAP | 21-184 | 9.4e-21 | 67.2 | In-house | 7-175 (293) | alignment | ||
Range on Protein: 21-184
Range on HMM: 7-175/293.0
ITVAASQGGRRYMEDRCVIHTERI------NNGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSDEDilEAIRQGFLMTHEQMRHVYDEwp
..| .| | |.| .|| . .. . .. .|||||.|..|||.. ..| .| .. .. | .. . |.. .. .... . . .
gayaerkGereemqdahviledldeqlrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpksdvsake..keikkclvdsfkktdeefLk..
YTASGYPS-TAGTTVSCVFIRNGKLYTGHVGDS-AIFLGTVENGE-LHSRPLTTDHKPESVHEQLRIAKAGGE
... |. |.|. .|.. . ||.. .||| |... . |.|. . | .|| ||.| . |. || ||||
laskakPvWkdGstatvvlvldnvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgv
|
|||||||||
| subfamily_LRR-PP2C_pd | Subfamily LRR-PP2C | 20-194 | 6.6e-20 | 64.5 | In-house | 7-162 (255) | alignment | ||
Range on Protein: 20-194
Range on HMM: 7-162/255.0
RITVAASQGGRRYMEDRCVIHTERINNGLLDWtfVGVFDGHGGEHASEYVRRHLlMNITKNqKFESNSDeDILEAIRQGFLMTHEQMrhvydewpytaSG
... . | | |||. ||. . .. |. . .||||||..|... .| .| .. ... |. . ...... . .. |. |
kvgfsdmiGrrptmedelviyGsfrdksdedy..yalfdGhgGraaakfaseel.ykilae.lldlnna.nPvkslkkaykeistqi...........se
YPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVENgelHSRPLTTDHKPESVHEQLRIAKAGGETAVKSGVTRV
.| ||| |.| . | | |||| . |. . .. |. |||| .|..||...|| . .||
rpkfiGttaasvliiedkvyianvGdsrvvlcqkdg...takrlsldhkPseeseekriselGGtvvstvvtsrv
|
|||||||||
| subfamily_Choan-PPM1K-like_pd | Subfamily Choan-PPM1K-like | 51-294 | 3.2e-19 | 62.5 | In-house | 20-275 (292) | alignment | ||
Range on Protein: 51-294
Range on HMM: 20-275/292.0
WTF-VGVFDGHG--GEHASEYVRRHLLMNITKNQKFEsnsdEDILEAIRQGFLMTHEQMRHVYDEwpytasgYPSTAGTTVSCVFIRNG-KLYTGHVGDS
|| |.|||| |.. ... .| ..... . .. ||. .. | . ...... . |.|.| | .|.. .|. .||||
ltflaavldGhGvnGdkvaqlaedtlevelleltrql....qelsealllrildiaakldkltid.......aresattavvcarvrddralilanvGds
AIFLGT-VENGELHSRPLTTDHKPESVHEQLRIAKAGGETA---VK----SGVTRvVWKRPQKMSQFMMMTSnsNEQKHHQNPQIMENiPFL--SVA-RS
|| . . . .||. ||||| |. || .||| |. | .| ||.| |. .. . . . | . .. . | | . .
rallgrclggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtar.vwrrrqqeGdlalsra..lGdfhlfeaGvvae.Pelqihagrqy
LG---DLWSYNEKTNM----FIVSPEPDLGVH-----RLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEE
|| ||. . . . .. . ||. | .| |||||||. .|.. . . .. | .|
lgrgpglwtrssiarhiayqhpltsdvplgldrklekeldsddaflvlasdGvldvllnaevvlllaksqe
|
|||||||||
| subfamily_PPM1K_pd | Subfamily PPM1K | 21-190 | 5.1e-19 | 61.4 | In-house | 6-161 (263) | alignment | ||
Range on Protein: 21-190
Range on HMM: 6-161/263.0
ITVAASQGGRRYMEDRCVIHteRINNGLLdwtFVGVFDGHGGEHASEYVRRHLLMNITKNQkfesNSDEDILEAIRQGFLMTHEQM-RHVYDEWPYTasg
. ... .| |. ||| .. .... || .|.|||||.| | ..| .| ... . ..|. . ... |. .... |... ... .
vGkdsliGkraenedriklk..eldpell...yvavfdGhaGsaaadfvhdklekilkrll....ekekdleivlknafeeldkklkrylefsvaea...
YPSTAGTTVSCVFIRNGK-LYTGHVGDSAIFLgtVENGElhSRPLTTDHKPESVHEQLRIAKAGGETAVKSG
..||| . ...|.|. | .||| | ||. .. ||.||.|| .|. || .||| . .|
ellssGttatvsllrdGtelvlaslGdsrail..crnGk..akkltrdhdPeleeekerikaagGsvewnsl
|
|||||||||
| subfamily_PPM1G_pd | Subfamily PPM1G | 14-107 | 1.6e-12 | 40.2 | In-house | 14-100 (473) | alignment | ||
Range on Protein: 14-107
Range on HMM: 14-100/473.0
QFGENMRITVAASQGGRRYMEDRCVIhterINNGLLDWTFVGVFDGHGGEHASEYVRRHLLMNITKNQKFEsnsDEDILEAIRQGFLMTHEQMR
.. |... ...| || | .|| | . |... .|.|||||. ..|| ..|. ..... .. ..|. .|... || |...
esneelsygasamqGwrvsqEDahnc....itdldedtslfavyDGHGGkevakyvakklpdllkaqkgyk...egdvekaleeaflalDeklk
|
|||||||||
| subfamily_Dicty-PPM1L-like_pd | Subfamily Dicty-PPM1L-like | 22-130 | 1.2e-10 | 33.8 | In-house | 10-121 (305) | alignment | ||
Range on Protein: 22-130
Range on HMM: 10-121/305.0
TVAASQGGRRYMEDRCVIHTERINNGLLdwTFVGVFDGHGGEHASEYVRRHLlMNIT----KNQK-----FESNSDEDILEAIRQGFLMTHEQMRHvyde
. .|.. |.| ||| .. | . ||||||.|. |.|||...| ..| | | |.|. ||||....| | . .
elyvsansrkyqedrnkvkislessqel..slfGvfdGhnGdiaaeyvkkkl.veivnkyvkenkvGysaknlnvddlpleaiksaslstdkssld....
wpyTASGYPSTAGTTV----SC
|.. ||||. .
...saesdnkkaGttlngssas
|
|||||||||
| PP2C_2 | Protein phosphatase 2C | 55-284 | 1.7e-08 | 27.0 | Pfam-A | 28-185 (212) | alignment | ||
Range on Protein: 55-284
Range on HMM: 28-185/212.0
GVFDGHGGE----HASEYVRRHLLMNITKNQKFESNS-DEDILEAIRQGFLMTHE--QMRHVYdewpytaSGYPSTAGTTVSCVFIRNGKLYTGHVGDSA
| ||.| ...... . .. ..|. . || . .|..|..|... | . . | .. .. .||.....|..|... ...||.|
aVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaq.......qeelkdyatTlllavitpgeivffqiGDga
IFLGTvENGELHSrpLTTDHKPESVHEQLRIAKAGGETAVksgvtrvvwkrpqkmsqfmmmtsnsneqkhhqnpqimenipflsvarslgdlwsynektn
|.. ..||... |..... | . | .. .. | .
ivvrd.rdgevql..lgepdsgeyanettfltsedaeeel............................................................
mfivspepdlGVHRLTGN-DFCLVLASDGMTNVMTGDQ
. ||. . .|.| .||. . .. ..
..........rirrlklepgdalllmTDGvsdslrkee
|
|||||||||
| PP2C_2 | Protein phosphatase 2C | 55-284 | 1.7e-08 | 27.0 | In-house | 28-185 (212) | alignment | ||
Range on Protein: 55-284
Range on HMM: 28-185/212.0
GVFDGHGGE----HASEYVRRHLLMNITKNQKFESNS-DEDILEAIRQGFLMTHE--QMRHVYdewpytaSGYPSTAGTTVSCVFIRNGKLYTGHVGDSA
| ||.| ...... . .. ..|. . || . .|..|..|... | . . | .. .. .||.....|..|... ...||.|
aVADGaGsakrSdkGarlaveaagealeklleeeseqeeeallrqieneilasvklkqeaeaq.......qeelkdyatTlllavitpgeivffqiGDga
IFLGTvENGELHSrpLTTDHKPESVHEQLRIAKAGGETAVksgvtrvvwkrpqkmsqfmmmtsnsneqkhhqnpqimenipflsvarslgdlwsynektn
|.. ..||... |..... | . | .. .. | .
ivvrd.rdgevql..lgepdsgeyanettfltsedaeeel............................................................
mfivspepdlGVHRLTGN-DFCLVLASDGMTNVMTGDQ
. ||. . .|.| .||. . .. ..
..........rirrlklepgdalllmTDGvsdslrkee
|
|||||||||
| subfamily_PPM1E_pd | Subfamily PPM1E | 230-334 | 2.1e-08 | 26.7 | In-house | 171-263 (265) | alignment | ||
Range on Protein: 230-334
Range on HMM: 171-263/265.0
LSVARSLGDlwsYNEKTnmfIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVfkeEEMVEIHEEINRNHSRCVLRSALQKWRslrADNVTIA
|||.|..|| ...| || |.|. .|.|.. .|.||.||. .|.. ......| ||... ..| . . .. .. .| .. .||.|.
LsvsRaiGD...vklkp...yvsgeadvaeveldgseeylilacDGlwDvvneeevvklv...eefladgaedlsevakllveaakeags...sDnitvv
TVIFD
|..|
vvfld
|
|||||||||
| PP2C_SIG_SM00331 | 52-329 | 1.7e-07 | 24.0 | In-house | 31-213 (217) | alignment | |||
Range on Protein: 52-329
Range on HMM: 31-213/217.0
TFVGVFDGHGGEHASEYVRRHL---LMNITKNQKFESNSDEDILEAIRQGflmtheqmrhvydewpytaSGYPSTAGTTVSCVF-IRNGKLYTGHVGDSA
... |.||.|. .|.. . . | |... .... |. . . .||.. .. . | . ... ...|||. ..|||
lllvvaDgmGkGlaAaaassqlrtalrellsegeelsqalkrlnraiyee...................keekgmfaTlllalydfssgklsyanaGdsr
IFLGTveNGELHSRPLTtdhkpesvheqlriakaggetavksgvtrvvwkrpqkmsqfmmmtsnsneqkhhqnpqimenipflsvarslgdlwsynekTN
..| . .|.| . ..
pyllr..dgklveilkd.................................................................................ve
MFIVS--PEPDLGVHRLTGN-DFCLVLASDGMTNVMTGDQaisivFKEEEMVEIHEEI--------NRNHSRCVLRSALQKWRslrADNVTIA
.... ||... .. |. . . |.|..||.|.... .. |.||.. || |. ... ...|..| .. |..|.
gaplGlepevsvdirelelekgdllllytDGltearsekg.....faeerleeiledlvdseaqelaqkiveellelakgsng...eDdiTvv
|
|||||||||
| subfamily_PPM1G_pd | Subfamily PPM1G | 123-186 | 1.8e-07 | 23.5 | In-house | 295-354 (473) | alignment | ||
Range on Protein: 123-186
Range on HMM: 295-354/473.0
TAGTTVSCVFIRNGKLYTGHVGDSAIFLGtvENGElhSRPLTTDHKPESVHEQLRIAKAGGETA
.||| . ... ||. .||| | .||. | .||||| .|. || ||||.
dsGttAvvaLlkekklivAnaGDsRcvls..rnGk..AldlslDHkPeDevEleRiekAGGkvd
|
|||||||||
| subfamily_KAPP-like_pd | Subfamily KAPP-like | 227-331 | 2e-07 | 23.3 | In-house | 168-264 (266) | alignment | ||
Range on Protein: 227-331
Range on HMM: 168-264/266.0
IPFLSVARSLGDLWSynEKTNMFIVSpEPDLG-VHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEmveiHEEINRNHSRCVLRSALQKwrSLRADN
| | |.|.||| . . |. ..| || . || | |..||||. .|..|..|| .| . ... . . . ..|..|.| .. ||
inGlavsralGdhfi..kelniGlis.epyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslyd....qqatedkmasslletaiqs..ikakdn
VTIATV
|.. |
vsvivv
|
|||||||||
| subfamily_Dicty-PPM-1_pd | Subfamily Dicty-PPM-1 | 228-331 | 2e-07 | 23.1 | In-house | 179-274 (276) | alignment | ||
Range on Protein: 228-331
Range on HMM: 179-274/276.0
PFLSVARSLGDLWSynEKTNMFIVSpEPDLG-VHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEmveiHEEINRNHSRCVLRSALQKwrSLRADNV
| |.|.||| . . |. ..| || . || | |..||||. .|..|..|| .| . ... . . . ..|..|.| .. |||
nGlavsralGdhfi..kelniGlis.epyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslyd....qqatedkmasslletaiqs..ikakdnv
TIATV
.. |
svivv
|
|||||||||
| subfamily_PDP_pd | Subfamily PDP | 89-181 | 4.5e-06 | 19.0 | In-house | 113-210 (398) | alignment | ||
Range on Protein: 89-181
Range on HMM: 113-210/398.0
EDILEAIRQGFLMTHEQM-----RHVyDEWPYTASGYPSTAGTTVSCVFIRNGKLYTGHVGDSAIFLGTVE-NGELHSRPLTTDHKPESVHEQLRIAKA
|.. ||....|| ... ... .| . . ....|.. ...|.. .|. .||.. ||..| .|. ....|..|. .. .| || |.
ekvkealkkaFlklDkdistealkkl.kekslreallvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikke
|
|||||||||
| subfamily_ILKAP_pd | Subfamily ILKAP | 230-308 | 4.8e-06 | 18.9 | In-house | 185-262 (293) | alignment | ||
Range on Protein: 230-308
Range on HMM: 185-262/293.0
LSVARSLGDLwSYNEktnmFIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEE----MVEIHEEINRNHSR
| |.||.|| . . |. ||. .|| || .||| ||. .|.. |.... . | | .|.|| . ...
levsrsiGdg.rfkr....lGvistPdvkkceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddrkikeeekkskee
|
|||||||||
| subfamily_PPM1G_pd | Subfamily PPM1G | 230-290 | 5e-06 | 18.8 | In-house | 363-426 (473) | alignment | ||
Range on Protein: 230-290
Range on HMM: 363-426/473.0
LSVARSLGDlWSYNEKTNM----FIVSPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVF
| ..| ||| ..| ..... ..| ||. |. || .| ||||.||. |||. .. . |
LnlsRAlGD.haYkkneeLplkeqmisAlPDikvltlteedeFlvlAcDGiWnvmesqevvdfvr
|
|||||||||
| subfamily_PDP_pd | Subfamily PDP | 51-81 | 6e-06 | 18.6 | In-house | 25-55 (398) | alignment | ||
Range on Protein: 51-81
Range on HMM: 25-55/398.0
WTFVGVFDGHGGEHASEYVRRHLLMNITKNQ
...|||||||| ...| |...|| ....
gvlfgvfDGHggaacaeavskrLlkyvaasl
|
|||||||||
| subfamily_PDP_pd | Subfamily PDP | 252-312 | 6.4e-06 | 18.5 | In-house | 271-331 (398) | alignment | ||
Range on Protein: 252-312
Range on HMM: 271-331/398.0
SPEPDLGVHRLTGNDFCLVLASDGMTNVMTGDQAISIVFKEEEMVEIHEEINRNHSRCVLR
. ||.. |.|. || ||||.||. .... ....|.| . . . .|... ... |.
taePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkkekepvkveeakltlk
|
|||||||||
| subfamily_KAPP-like_pd | Subfamily KAPP-like | 52-193 | 6.6e-06 | 18.3 | In-house | 35-167 (266) | alignment | ||
Range on Protein: 52-193
Range on HMM: 35-167/266.0
TFVGVFDGHGGEHASEYVRRhLLMNITkNQKFESNSDEDILEAIRQGFLMTHEQMRHVYDEWpytaSGYPSTAGTTVSCVFIRNGK---LYTGHVGDSAI
.. .||||| | |.. .. |. .. ... .| ..| . | . . .. ...| . . . |. .. ..|. | .. ||||.
alfavfdGhaGkGaadaakk.lfpkel.ekllkstkqddGGdniydqskllenafkevdakl....kdfeyeGatatlalvwsdGqqrylqvanvGdssa
FLGTvENGelhSRPLTTDHKPESVHEQLRIAKAGgeTAVKSGVTR
|| | | |. ||| . .|. || . | .. . ||
flsr.Gne...slelskdhkakdpeekqrikddG..itlsdnqtr
|
|||||||||
| subfamily_TAB1_pd | Subfamily TAB1 | 32-105 | 9.4e-06 | 17.6 | In-house | 13-81 (333) | alignment | ||
Range on Protein: 32-105
Range on HMM: 13-81/333.0
YMEDRCVIHteRINNGLLdwtFVGVFDGHGGEHASEYVRRHLLMNITKNQKFESNSDEDILEAIRQGFLMTHEQ
..||.. . ...|. . .||||. |..|...| .| .. ..| .. ..... | ... | . ..
evedkvflf..ktendpi...lyavFdGydGnkaakfveqrLvaellleqltdelaeaevkevlkrafeeverk
|
|||||||||