Gene Y71G12B.30 in Caenorhabditis elegans

Synonym: CELE_Y71G12B.30, Y71G12B.30

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP229_AA protein Get Run
CeleP229_AA_29-309 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 29-312 1e-170 559.6 In-house 1-284 (284) alignment 
Range on Protein: 29-312
Range on HMM: 1-284/284.0
PGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQ
|.|||.|..|||.||.||||||.||||..||||||||.|.|||||||||||...|..|.|.|....|...|||||||.||||||||||||||||.||.|.
pvncqkllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpd

KMFLLRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGF
|.|||||||||||||||||||.|||.|||..|||.||.||..|||||.|. .|.||||||...||.|.|.|...||.||.|.|...||.|||| . |.|.
kvfllrgnhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegy

QDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTFGHDL
..||||||.|||...||||..||||||.||||||||||||||||.|||||||||.|||..||..|||.|........... .||
kesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkpdl
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 96-309 8.3e-126 412.4 In-house 100-313 (317) alignment 
Range on Protein: 96-309
Range on HMM: 100-313/317.0
SSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSL
 ..|||||||.|||||||||..||||..||.|.|.|||||||||||||.|||||.|.|.|||..|||.||.||...||||.|. .|.||||||.. ||.|
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldl

EQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVL
.|.|...||.||.|||. .||.|||| . | |...|.||||.|||...||||..|..|||.|||||||.||||||||.|||||||||.|||..||..|||
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl

QVATNMECTINTFG
.|.......||.. 
svdkklkisinvlr
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 23-306 9.6e-111 362.5 In-house 11-289 (298) alignment 
Range on Protein: 23-306
Range on HMM: 11-289/298.0
LTQSWSPGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAY
|..| |  .  .  .|... ...  |.. | | .. .|..||...|||||||. ||| .||  |||.      .. |||||||.||| ...|||.||.||
lsvslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfpp......danylflGdyvdrGrqnlevivlllay

RLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRY-SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADP
.. .|...||||||||   .| .||||.|||||| |..||..|| .|  .||.|..||||.|||||.   | ||.|. |..||.|  .  .  || ||||
kvkypnnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadp

VSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTIN
 . | |.... ||.. |||| .||.. ||...||.||||||| |||||||.|||||||||| |||.|||  ||..|  ..... .
enavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfe
subfamily_PPP1C_pd Subfamily PPP1C 33-305 1.2e-110 362.1 In-house 7-273 (282) alignment 
Range on Protein: 33-305
Range on HMM: 7-273/282.0
QTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSqkdkssRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFL
.. ..|.|| ... .|||.. ..|. ||.||||.|.||||||..||| .|...|.|  |      .|||||||.||| .|.|.|.||.||.. .|...||
evklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpes......nylflGdyvdrGkqsletivlllaykikypenlfl

LRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSP
|||||||  .|. ||||.|||||||..|..||. .| |.||.|.|  .|.|.|||.   | |||||.. |||..... |.  || |.|| . |.|.... 
lrGnhesasinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsend

RGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTI
||  ..||. .|..| .|..||||||||||| |||||||...|||.|||| |||.||| ||||.| ... .. 
rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsf
PP2Ac_SM00156 36-308 1.5e-105 345.1 In-house 1-267 (271) alignment 
Range on Protein: 36-308
Range on HMM: 1-267/271.0
FQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFdiygfpHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRG
....|..|.. ...| . .|.. .|..||||..||||||..|||...      .  .. ....|.|||||.||||.|||||.||||. .|.|.|..||||
lskeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll......elageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRG

NHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGA
||||..||. |||..|.||.|.  .|| |. || ..||.|.|. .|.|||||..  | ||..|....|. .... |.  || |.|| . . ||| | ||.
nHEsssvnkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrgl

GHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
..||||. |||| .|..|.||.|||.||..||||||||||||||||| ||..|.|..|||.| .|....|...
svvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieql
0045823 Metallo-dependent phosphatases 33-309 1.9e-102 336.3 In-house 40-322 (473) alignment 
Range on Protein: 33-309
Range on HMM: 40-322/473.0
QTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSqkdkssRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFL
. |. |.........|.| ..|||. ||........||||||..||| .... |||..       |..||||..||||.|.||. ||.|. ...|...||
egllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfpped......rlvflGDlvDrGpdslevlelllalkikypgnvfl

LRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPvSGVVG-----
||||||.| .|  |||..|. ..|.. ||| |.  . ..||.|..||.| ..|||.. .| .|.||.| .|| .| | |.  ||.|.||   . |     
lrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.weddgdgllr

---FQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKK------LVTIFSAPCYCGHFDNLGAVLQVATNMeCTINTFG
   |. ||||||..||.  |.|| .|..||||||.|..|..|||.. |.|      ..|.||||.|||...||.|||..  .. ... .| 
lrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfd
0049330 Metallo-dependent phosphatases 31-308 5.5e-99 324.1 In-house 25-296 (309) alignment 
Range on Protein: 31-308
Range on HMM: 25-296/309.0
NCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPhvsqkdKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKM
 .. |..|.|.......|.| ...||. ||........||||||..||| .....|||      .. |..||||..||||.|.||..||.|. ||.|...
lklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfp......pedrlvflGDlvdrGpdslevlllllalkllypdnv

FLLRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQD
||||||||.| .|. |||..|..|.|.. |.| |.  . ..||.|..||.|.|.|||.. .||.|.||.|..||..| . |.  ||.|.||.  . ||..
fllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpiregfap

SPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
.|||.|.|||. .|..| .|..||||.|.|..|..||..|.|.||.|.|||| |||...||||||..  ...... .|
nprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllf
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 26-307 1.1e-96 316.6 In-house 14-290 (299) alignment 
Range on Protein: 26-307
Range on HMM: 14-290/299.0
SWSPGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLL
  | ..  .  .|.|....|  |...| ...  ||.|||. .|||||||. ||| .||. |||        . .||||||.|||   .|.||||..... 
gmsekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfpp......dvnflflgdyvdrgrqnlelitlllcfkik

HPQKMFLLRGNHESRPVNMQYGFYNECKRRYSV-TLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSG
.|...|.||||||   .|  ||||.||..||    |.  || ||  |||. ..|.||.|||||.   | .|.|. ...|| |  .  .  || ||||   
yperffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqs

VVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINT
|....   ||  .|||.  |..  .....||. |||||| |||||||.|||||||||| ||| |||  |...|  |. ||.  
vkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvv
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 37-305 1.2e-96 316.1 In-house 7-269 (280) alignment 
Range on Protein: 37-305
Range on HMM: 7-269/280.0
QEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGN
.| .| ..  . .. .  .   .|..|||..|||.|||. ||| .|.  .||        . |||||||.||| . .||| ||.||.. .|.....||||
keadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfpp......dqnylflgdyvdrgrqqlevillllaykvrypnnflilrgn

HESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGAG
||   .| .|||..|.|||||  ||. ||  .  .||.|.|.|||.|||||.   | ||... |..|| |  |  .  || |||| . | |. ...||. 
hevisinrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvs

HVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTI
..||.  ||.. ||...|||.| |||| |||||||||||||.|||| |.|.|||  |||.|  ... ..
vifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsf
PPP_3 36-308 4.7e-92 300.8 In-house 2-269 (271) alignment 
Range on Protein: 36-308
Range on HMM: 2-269/271.0
FQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVsqkdksSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRG
..|.|. |.. ...| . ||.. .||.||||.|||||||..||| .|.. |...       ..|||||||.||| .|.||..||.|. ...|....||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspe......tkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRG

NHESRPVNMQYGFYNECK-RRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRG
||||| .|  |||..|.. .... ..|...|  | ..||.|.. ......|||.   . ||.|| . .|.... . |   || . .. .   |.. |.||
nhEsrqinkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrG

AGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
|| .||.  ..||.|| ||.||.|||.....|||...|.|.||.|||| ||....|.||.|.............
agllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql
0053225 Metallo-dependent phosphatases 30-308 7.4e-92 300.8 In-house 16-288 (293) alignment 
Range on Protein: 30-308
Range on HMM: 16-288/293.0
GNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPhvsqkdKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQK
  .. |. |.|...... |.| ..|||. ||........|||||...||| .....|||      ...|..||||..||||.|.||..||.|. ||.|..
llllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfp......pedrlvflGDlvdrGpdslevlelllalkllypdn

MFLLRGNHESRPVNMQYGFYNECKRRY-SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVsGVVGF
..|||||||.. .|. |||..|..|.| .  |.. ..  . ..||.|..||.|...|||.. .| .|.||.| .||..| . |.  ||.| ||   . |.
vvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.lwsgw

QDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
  |.||.|.|||. .|..| .|..||||.|.||||.|||... |.||||.|||| |.|...|||||| . ... ... .|
lpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklf
subfamily_PPZ_pd Subfamily PPZ 36-308 8.8e-89 290.9 In-house 25-291 (300) alignment 
Range on Protein: 36-308
Range on HMM: 25-291/300.0
FQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRG
....||..||..||| |  .|  ||.  .| | ||.|||. ||| .|   |||       |. |||||||.|||  |.| | ||..|.. .|...|||||
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfpp......sanylflgdyvdrgkqsletillllcykikypenffllrg

NHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGA
|||   |   ||||.|||||  . ...||  .|  .||.||| |.|.|.|||.   | |...|    ||||. |.|.  || |.||      ..|  || 
nhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergv

GHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
 ... . ....| .|| .||..||| || |||||| |. |||.|||| ||| ||| |||. |.  . |... .
sycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfell
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 39-305 6.7e-88 287.8 In-house 6-268 (284) alignment 
Range on Protein: 39-305
Range on HMM: 6-268/284.0
KEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHE
...  . ..| . | |.|| .|...|. ||||||||| ||| .||  ||||       . |||||||.|||   .| | |||||... |...|.||||||
edvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfph......ranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhe

SRPVNMQYGFYNECKRRYS-VTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADV-GIPSDLCWADPVSGVVGFQDSPRGAG
   .| .||||.||.|||   ..| .|.  |  ||| |.|| ||.|||||.   |  . |.   .|| |  .   .  |. |.||     |..   ||  
cslinkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvs

HVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTI
.|||  ..... .....||.||||||| |||||||...|||||||| |||.|||  ||. |  |. |..
yvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsf
PPP_1 37-296 1.9e-86 282.6 In-house 2-263 (264) alignment 
Range on Protein: 37-296
Range on HMM: 2-263/264.0
QEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPhvsqkdKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGN
.|.|..|.. ...| . ||.. ||.....|.||||||||.||| .| . |..      ....|||||||.||| .|.|...||.|. | .|...||||||
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggps......petnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGN

HESRPVNMQYGFYNECK-RRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLC-------WADPVSGVVGF
|||| |.  |||..|.. ..|| ..|.|.. .| ..||.|.. ..|...|||.   | .|.|| . .| |.... |  .||        . |. .   ..
HEsrqvtkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeav

QDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQ
..|.||||..||.  ...|..|..|.||.|||.|...||||....|.||||||. |. ...|.||...
ansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 35-306 2.2e-86 282.4 In-house 9-277 (287) alignment 
Range on Protein: 35-306
Range on HMM: 9-277/287.0
LFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLR
 |..|.|.|.  ...| .   |  ||.|||.||.||||||..||| .|.  | .         .|||||||.|||. |.||. |||..... |.|. |||
afsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaap......kvqylflGdyvdrGakslevslllfslkiaypkkvhllr

GNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADV--GIPSDLCWADPVSGVVGFQD-S
|||| . .| .|||..| ||...  ||..|.  |  .||||.|. ||.||||||   | ||...  ...||   .   |.  || ||||     .|.   
GnhevkkinklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnk

PRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTIN
 |.   |||. .| .. .|...|||||||.|. .||.|..||.|||.|||| |.|.  |||||..|.  .| .. 
iraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfv
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 36-306 1.5e-85 280.0 In-house 23-290 (297) alignment 
Range on Protein: 36-306
Range on HMM: 23-290/297.0
FQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVsqkdksSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRG
  |. ....   | . | ..   .|..||. .|||||||| ||| .|   |.|        . |||||||.||| |||| | ||.||..  | ..|||||
iteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwppt......anylflgdyvdrgrfsietivlllaykvkfpgnlfllrg

NHESRPVNMQYGFYNECKRRY-SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPF---GLLSLEQIDEFQRPTDIADvGIPSDLCWADPVSGVVGFQDS
|||   ||  ||||.||..|| || .| .||  |  .||. ..  .|.|||||.       ..|. . ...|.|.  . .. .|| ||||.||. || . 
nhecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegke.rlvadllwadpisglsgfmen

PRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTIN
 ||||  ||  .| .   .|||||..|||||| ||||||| .||||||||| |||.|||  |.. .  ...|...
qrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfe
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 34-306 1.1e-80 263.8 In-house 6-272 (281) alignment 
Range on Protein: 34-306
Range on HMM: 6-272/281.0
TLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPhvsqkdKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLL
  . ..||... . ..  | .|    ||..|... ||.|.||.||  .|.. | .         ...|||||.|||| |.||. |||.... ......||
vqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrv......peevlvflgdyvdrgpqslevlillftlkiryrdrivll

RGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPR
|||||   || .||||.||. .| . |.  ||  |  .|. | .  |..|||||.   | .|... .  .| .  | |.  || |||| . | ... | |
rgnheiasvnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassr

GAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTIN
|....||.. |..   .....||.||||||.|||| .. .||.|.||.| || .. | .|||.|  ... .. 
GssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislv
subfamily_PPP4C_pd Subfamily PPP4C 35-308 3.3e-80 262.4 In-house 15-282 (288) alignment 
Range on Protein: 35-308
Range on HMM: 15-282/288.0
LFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfphvsqKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLR
| .|.|. ..| .||| . .|    ....|||.||||||||.||| .|.. |      . .. .||||||..||| .|.| . || |... .|... |.|
likeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvgg......dvpetnylflgdfvdrgfysvetfllllalkvrypdritlir

GNHESRPVNMQYGFYNECKRRY-SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVvGFQDSPR
|||||| .   ||||.|| |.| |.....     |  ..|.||. |.|.|.|||.   . .|..|   .| ... . |. .|| |.||     |.  |||
gnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae.gwavspr

GAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
|||..||. .|..|||. ...||.||||.||.|| .  ..|..|..||| ||    |. |.|..  ...   . |
gagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkif
subfamily_PPP2C_pd Subfamily PPP2C 32-309 2.7e-79 259.4 In-house 14-284 (290) alignment 
Range on Protein: 32-309
Range on HMM: 14-284/290.0
CQTLfQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfphvsqKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMF
|..| .|.|. |.| .|.| . ||    |...|||.|||.|||| ||| .| | |      |   . |||||||.||| .|.| .||| | .. ..... 
ckql.eesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkigg......kspdtnylflgdyvdrgyysvetvtllvalkvrykerit

LLRGNHESRPVNMQYGFYNECKRRYS-VTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVsGVVGFQD
.|||||||| .   ||||.|| |.|.  .... |   | ..||.|.| ..|.|.|||.   . .|..| ...|  .. . |  .|| |.||     |.. 
ilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgi

SPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTFG
||||||. ||.   ..||.. .| ||.||||.||.||..  |...||||||| ||    | .|.|..  ... ....| 
sprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfd
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 97-309 1.7e-78 257.1 In-house 120-332 (339) alignment 
Range on Protein: 97-309
Range on HMM: 120-332/339.0
SRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLE
 ||||||||.||||||.||. || | .| .|....||||||||| ||  |||| | . ||   ||| ||  |  .|.||..   ||||||||   | |..
krylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfn

QIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQ
|.  |.|| .| |||. .|| ||||     |.. | |||  |||  ... | .|. |....| |||| ||||||  ..|||||||| |||. ||  ||. 
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs

VATNMECTINTFG
.  ... .|| | 
idkklkisinvfr
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 33-308 1.1e-77 254.2 In-house 3-297 (302) alignment 
Range on Protein: 33-308
Range on HMM: 3-297/302.0
QTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYgFPHVSQKDK------SSRYLFLGDYIDRGPFSIEVITLLFAYRLLH
.. ....|.. ..    |.. ||    || .|||| ||||||||||. ..     ..  .|.|      |....|||||.|||. ||| |.|.||...|.
kkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnar.vskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvly

PQKMFLLRGNHESRPVNMQYGFYNECKRRYSVT----LYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRP-TDIADVGIPSDLCWADP
|..  |||||||.. .|. ||| .| . |.. .    ..| |. .|  ||| |.|| .|.|.||||   | |||.|.. .|| .....  .  || .|||
ptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadp

VS--GVVGFQDSP-------RGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
.   ...  .. |       ||  .|| ||.|... ... |.|||||||..  |. |||||||.|||||| |    || ||||.|.|| . .| ..
ldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvl
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 33-308 2.2e-77 253.2 In-house 4-298 (302) alignment 
Range on Protein: 33-308
Range on HMM: 4-298/302.0
QTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfPHVSQKDK------SSRYLFLGDYIDRGPFSIEVITLLFAYRLLH
.. ....|.. ..    |.. ||    || .|||| ||||||||||. ..     ..  .|.|      |....|||||.|||. ||| |.|.||...|.
kkeysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarv.skeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvly

PQKMFLLRGNHESRPVNMQYGFYNECKRRYSVT----LYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRP-TDIADVGIPSDLCWADP
|..  |||||||.. .|. ||| .| . |.. .    ..| |. .|  ||| |.|| .|.|.||||   | |||.|.. .|| .....  .  || .|||
ptnyillrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadp

VS--GVVGFQDSP-------RGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
.   ...  .. |       ||  .|| ||.|... ....|.|||||||..  |. |||||||.|||||| |    || ||||.|.|| . .| ..
ldvqllaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvl
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 35-307 3e-74 242.6 In-house 15-285 (290) alignment 
Range on Protein: 35-307
Range on HMM: 15-285/290.0
LFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLR
 |..|.|.||  ...| .   |  ||.|||..| ||||||...|| .||  |.|         ..||||||.|||. |.||  ||| |......|. |||
afsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgypp......kvkflflgdyvdrgakslevslllfcykiryskkvhllr

GNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDI--ADVGIPSDLCWADPVS-GVVGFQ-D
|||| | ||  |||..|  |. .  |.  .|  |  ..||| || .|.||||||   . | | .  ...|      | |.  || ||||       .. .
gnhevrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialn

SPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINT
  |.   |||. .. .. .|. |.||||||.|  .|..|  ||||||.|||| |.|.  ||||...|.  .| .| .
kqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivv
subfamily_PPP5C_pd Subfamily PPP5C 35-308 4e-73 239.2 In-house 33-306 (322) alignment 
Range on Protein: 35-308
Range on HMM: 33-306/322.0
LFQEKEIIEICYRAREAFWKEPMKLEIEAP----VTICGDIHGQFEDLLSMFDIYGFPhvSqkdKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKM
 ...| ...|  .|.| . |.|  .||. .    .|.|||||||| ||| .|...| |  |   ..  ||| ||..||| ||.||| .|....||.|...
klhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlp..s...eenpylfnGdfvdrGsfsveviltllgfkllyPnhf

FLLRGNHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPF-GLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSgVVGFQ
|| ||||||  .|  ||| .|.| .|. .... |.  |  .||. ..  ... .|||..    ..|... . .| ..  . |.  .| |.|| .   | .
flsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqe.anGrs

DSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQV-ATNMECTINTF
 | || |. ||    |.| .. .|.||.|.|.| ..|||.  | ||.|.|||| || . .|.||.... ..... ...||
pskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktf
subfamily_PPP3C_pd Subfamily PPP3C 37-301 2e-72 237.4 In-house 42-313 (452) alignment 
Range on Protein: 37-301
Range on HMM: 42-313/452.0
QEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfphvsqKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGN
.|.....|  .| . . ||.  ||.|||.|..||||||| ||| .|.. |      . .|..|||||||.||| ||||..  |.| .. .|...||||||
eeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgG......dPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGn

HESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQ-------
||.| .   . | .||| .|| ..|...  .| ..|| |.. .. .|.|||.   . ||..|....|  ..   |   || |.||.     ..       
hecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvp

DSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFAD------KKLVTIFSAPCYCGHFDNLGAVLQVATNM
.|.||  .... ..| || .| .|  |.|||..  .||. . .        |.|.|||| |.. ..| .|||.. .| 
nsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyennv
subfamily_PPP6C_pd Subfamily PPP6C 31-308 2.7e-72 236.3 In-house 11-281 (290) alignment 
Range on Protein: 31-308
Range on HMM: 11-281/290.0
NCQTLfQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfpHVSQKdkssRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKM
.|. |  |... ..| .  . . .|     ...|||.|||||||| ||. .|   |  .| ..    .|.||||..||| .|.| .|.|.. .. .|...
kckyl.pendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtgg..qvpdt....syvflgdfvdrgyysletftrlltlkakypdri

FLLRGNHESRPVNMQYGFYNECKRRYSV-TLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPvSGVVGFQ
 ||||||||| .   ||||.||...|   . .  .   |  ....||. ....|.|||.   .  |.||   .| ..|.  |  .|| |.||   |  ..
tllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.edvetwa

DSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTF
 ||||||..||.  .|||..  .|.||.||||.|..|.... |.||||..||| ||    |. ..|.. .. | . . |
vsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklf
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 36-305 6.5e-70 228.8 In-house 6-269 (280) alignment 
Range on Protein: 36-305
Range on HMM: 6-269/280.0
FQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfpHVSQkdksSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRG
.  .||| |       | .|    | |||. . |||| |..|.  .||. |  .| .     . .|||||.||||  |||. |||. .. . ....||||
mtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdlig..rvpe....eklmflgdyvdrgpqgievlillfclkiryrdriyllrg

NHESRPVNMQYGFYNECKRRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGFQDSPRGA
|||.  ||  |||| ||. .| | |.  || .|  ||.....  |..|||||.   |. |. | .  || .  | |.  || |.||     |.  | || 
nhetpsvnkiygfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgi

GHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTI
 ..||.. |..  . ...|||.|||||| ||||..| ..|.|.|| | || .| |  ||. . .|.. ..
symfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsf
subfamily_PPG1_pd Subfamily PPG1 35-309 4.9e-68 222.6 In-house 13-294 (300) alignment 
Range on Protein: 35-309
Range on HMM: 13-294/300.0
LFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGfphvsqKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLR
|. |  . |.... .| . ||    ||..|||. ||.|||| |.| .|.| |      .   . |||||||.||| .|.| |.|| . .| .| .. |||
llpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkigg......qvpdtnylflgdyvdrglysvetisllivlklrypsritllr

GNHESRPVNMQYGFYNECKRRY--SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPV---------S
|||||| .   ||||.|| |.|    .... .   |  . |.||.   |.|.|||.    ||..||  ..|  .. . |  .|| |.||           
gnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhp

GVVG--FQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTINTFG
   |  |. |.||||. .|.  |..| .. ... |.||||....||. . |.|| |..||| ||    |  ..|..  . |  .|.. 
dregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvye
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 59-303 1.2e-66 218.0 In-house 3-248 (263) alignment 
Range on Protein: 59-303
Range on HMM: 3-248/263.0
LEIEAPVTICGDIHGQFEDLLSMFDIYGfphvsqKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRYSV
||..||. |||| |||..||| .|.  |          ..|||||||.||| .|.||| |||. .|  |.||.||||||| . .| .|||. | |.|.  
lelqapinicgdthgqyndllrifnacg......aatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqr

-----TLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADV-GIPSDLCWADPVSGVVGFQDS-PRGAGHVFGEATVKEFNEKF
     ..|. |.  |  |||||||  ||.||||||   | ||..|     | . |    .  || ||||     ||.    |    |||.  | .. ...
eevyesvynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrl

KLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMEC
 .||||||||||  || ||||..|.|.|||  |   . |  ||. |   .| 
didlivrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlel
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 32-303 2.2e-63 207.3 In-house 16-284 (307) alignment 
Range on Protein: 32-303
Range on HMM: 16-284/307.0
CQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHvsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMF
 .  .  .|. .. | |.  |  |   ..|. |. . ||.||||.||. || . | |        . |.| |||.||| .|.|.| |||.|.. .|... 
hkiqytkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrpp......etvyvftgdyvdrgllslecilllftykicypeniv

LLRGNHESRPVNMQYGFYNECKRR---YSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLCWADPVSGVVGF
|||||||   || .||||.||          ..  || .|  .|. |..  .|.|||||.   |  |... .  .|      ||  |. ||||   |. .
llrgnheiarvnkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfew

QDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMEC
. | ||.|  ||   . .   .. ..||.||||...|||  .. .||.|||||| ||  . | |.||.|   .  
kassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgi
PPP_2 65-262 3.3e-62 202.7 In-house 1-197 (198) alignment 
Range on Protein: 65-262
Range on HMM: 1-197/198.0
VTICGDIHGQFEDLLSMFDIYgfphvsQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECK-RRYSVTLYET
||.|||.|||..||| .|.        .. ....|||||||.||| .|.||..||.|. | .|....||||||||. ||  |||..|.. .... ..|..
vtvcGDlHGqldDLlilfkng......lpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykk

FQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIADVGIPSDLC----WADPVSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRA
.|  | ..||.|.. ......|||.   . .|.|| . .|.... . |   ||     . || .   ... | |||| .||. ...|. ||.||.||.||
lqevfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRa

HQV
|.|
Hev
PPP_4 65-262 7.5e-62 201.9 In-house 1-196 (197) alignment 
Range on Protein: 65-262
Range on HMM: 1-196/197.0
VTICGDIHGQFEDL-LSMFDIYGFPHVSqkdksSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRRYSVTLYET
||..||||||..|| |..... |.|. .     ..|.|||||.|||..|.||..||.|. |  |....||||||||. .|  |||..|...... .....
vtvvGDiHGqlddlllkllkngglpsee.....rsyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkk

FQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIA-DVGIPSDLC-WADPVSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQ
.|  | ..||.|.. ......|||..  | ||..|.. .|....  . .   ||  |.|| .   |...| ||||..||.  ...| || .|.||.|.|.
lqdvfdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshe

V
.
l
PPP_5_Dcr2 65-263 8.3e-58 188.6 In-house 1-199 (199) alignment 
Range on Protein: 65-263
Range on HMM: 1-199/199.0
VTICGDIHGQFEDL-LSMFDIYGFPHVsqkdkSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECKRR-YSVTLYE
||.|||.|||..|| | .|.  |.|       . .|.|||||.|||..|.||..||.|. |. |....|||||||.. .|  |||..|.... ..  .|.
vtvcGDlHGqlddlllilfkeggdpse.....erlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiyk

TFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQRPTDIA-DVGIPSDLC-WADPVSGVVG-FQDSPRGAGHVFGEATVKEFNEKFKLDLIVRA
...  | ..||.|.. ......|||..  . |.|.... .|...|  . |  .||  |.||.. . | .. | ||||..||.  ...| || .|.||.|.
ilsdvfdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirs

HQVV
|...
helk
subfamily_PPPLV_pd Subfamily PPPLV 42-298 3.6e-52 170.5 In-house 3-277 (290) alignment 
Range on Protein: 42-298
Range on HMM: 3-277/290.0
IEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIygFPHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHESRP
. .|  | . . .|   ||...|. . ||.||...||  . .   .  .  .   . .||||||.|||.||.|.|. |.| ..| | |..||||||| . 
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekv..lwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnheles

VNMQYGFYNECKRRYSVTL---YETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIDEFQR-----PTDIADVGIPSDLCWADPVSG---------
|  .. .. |.. ..  .|   .|.|. .|  .|| |..  ...|.|.|||    .  .|   |      . ||    .  |. |.|| ..         
vqesieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgel

--VVGFQD-SPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVA
    || | . || ||||.|.... | ..  |. ..|||.|   |...  . .|.|.||.  |||  ..   .|   
vlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvdk
Metallophos Calcineurin-like phosphoesterase 64-263 1.9e-36 119.2 Pfam-A 2-199 (200) alignment 
Range on Protein: 64-263
Range on HMM: 2-199/200.0
PVTICGDIHGQFEDLLsmFDIYGFPHVSQKDKSSRYLFLGDYIDRGPFSIEVITLL--FAYRLLHPQKMFLLRGNHESRPVNMQYGFYNECK--------
.....||.||...||   ..   . .. .. |   .|||||..|||. |.|.. ||  ... || | . |||||||||.|.|  |||..|.         
rilvigDlHgglddle..dlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglan

--------------------------RRYSVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLEQIdefqrptdiadvgipsdlcwadpvsgvvg
                           ..    .| ... |...||.|.|.|.| ..||..   . | ..|                             
geeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.............................

fqdsprgAGHVFGEATVKEFNEKFKLDLIVRAHQVV
       ..  ||.  . .. || ..||..|.|. .
.......gselfgpdalekllekygvdlvlrGHtHk
subfamily_PPP7C_pd Subfamily PPP7C 41-203 3.7e-35 114.4 In-house 38-201 (383) alignment 
Range on Protein: 41-203
Range on HMM: 38-201/383.0
IIEICYRAREAFWKEPM----KLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSQkdkssRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGN
...| . |.. . . |     .  |   ||.|||.||...||| ..   |.|  ..      |.| ||..|||  |.|.. .|.|. |..|....| |||
vllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseen.....pyvfnGdfvdrGkesveillillalllvypkevylnrGn

HESRPVNMQYGFYNECKRRY---SVTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPfGLLSLEQIDEFQR
||   .|..||| .| . .|   .  . ....  |  .||....  .|. .||||     .|| .|. .|
hedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis.dktdlelldkier
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 28-96 5.8e-34 110.7 In-house 1-69 (317) alignment 
Range on Protein: 28-96
Range on HMM: 1-69/317.0
SPGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSQKDKS
||..||.||.|||.||.||||||.|||||.|||.||||||.|||||||||||...|..|.|..||..||
spkkcqdlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwplssqeeks
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 31-93 2.5e-19 62.6 In-house 6-68 (339) alignment 
Range on Protein: 31-93
Range on HMM: 6-68/339.0
NCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHGQFEDLLSMFDIYGFPHVSQK
 .  ||   |. |.|.||||  | ||. |..|||. . |||||||.|||.|.|. |.|  ||.
tsldlfcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwplssqe
subfamily_PPP7C_pd Subfamily PPP7C 215-305 5.7e-18 57.8 In-house 239-329 (383) alignment 
Range on Protein: 215-305
Range on HMM: 239-329/383.0
DLCWADPVSGVVGFQDSPRGAGHVFGEATVKEFNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQVATNMECTI
|. |.|| .    . .. ||.|  ||    |.. .|..|.|..|.|.  ..||||  |||..|||||  |  .  | || ........  |
dilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltpri
subfamily_YNL217W_pd Subfamily YNL217W 66-141 3.9e-08 26.1 In-house 13-78 (235) alignment 
Range on Protein: 66-141
Range on HMM: 13-78/235.0
TICGDIHGQFEDLLSMFDIygfpHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLfayrllHPQKMFLLRGNHESRP
 . ||.|| ...|. ..|     .. .||.    ...|| |..|| |.||. ..      . ..   ..||||   
lvvGdvhgaYDelieLldd....kiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelv