Gene Y94H6A.7 in Caenorhabditis elegans

Synonym: CELE_Y94H6A.7, Y94H6A.7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family LMWPTP
Subfamily LMWPTP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP232_AA protein Get Run
CeleP232_AA_5-162 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_LMWPTP_pd Subfamily LMWPTP 6-161 9.4e-64 203.8 In-house 1-151 (152) alignment
Range on Protein: 6-161
Range on HMM: 1-151/152.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
.|.||.|||||||||||||||. ....|.| .|.|.|||.||  ||.|| ||.||. .|||.|.| . ||||... .||..||||..||..|...|...|
kkkvlfvClGniCrspiaEavlrklvekkglkedwkvdsaaissyhvGkepdkRalsilkkhglkss.hrarqitkedfsefdyilamDesnlkelkkla

RkvPKTERKAEILMLGVQDvMAGKREVPDPYYeSGSKQFDEVLQQCVKCCDAFLDK
.   |.|.||..|.|| .| ..||. . |||| ...|.|..|..|...||.|||.|
k..ekkeskakvlllgeyd.kkgkeiiedpyy.gdekdFeavykqikecckaflkk

0046251 Phosphotyrosine protein phosphatases I 6-162 3.4e-43 137.7 In-house 5-158 (159) alignment
Range on Protein: 6-162
Range on HMM: 5-158/159.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREE-WHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEI
 |.||.||.|||||||.|||.. . |...|  .  ..||| .. ..|.|..||.||. .||..||.   ||||  ...||..||.|..|||.|..||...
kkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsalhvgeppdpravavlkelgidls.hrarqlteedfeefdlilamddsnlrdllrl

ARKvpKTERKAEILMLGVQDVMAGKREVPDPYYESgSKQFDEVLQQCVKCCDAFLDKI
| .  .. .|  .|.  ....     .|||||| .  . |.|||........|.|.|.
apg..dargkvllllefagllellhwdvpDPyygg.leaFeevldlieeaveallekl

0053360 Phosphotyrosine protein phosphatases I 6-162 8.7e-42 133.0 In-house 5-156 (157) alignment
Range on Protein: 6-162
Range on HMM: 5-156/157.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
 |.||.||.|||||||.|||.. . |...|  ....|||  . ..|.|...|.||. .|...||.   ||||  ...|...||.|. |||.|.|.|....
mkkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsalhvggpvdpravevlaelgidls.hrarqlteedleefdliltmddsnleellplf

RKVPKTERKAEILMLGVqDVmaGKREVPDPYYESGSkQFDEVLQQCVKCCDAFLDKI
... .. .|  .|.  . ..    ..|||||| . .  |..||........|.|...
pglleakgkvllllefa.gl..lhwdvpDPyyggle.afelvldlieeaveallell

0048765 Phosphotyrosine protein phosphatases I 7-162 1.4e-41 132.3 In-house 3-153 (154) alignment
Range on Protein: 7-162
Range on HMM: 3-153/154.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.|||||||.|||.. . |...|  ....|||  . .||.|...|.||. .|...||.   ||||  ...|...||.|. |||.|.|.|.....
kkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsayhvgepvdpravevlaelgidls.hrarqlteedleefdliltmddsnleellplfp

KVPKTERKAEILMLGVQDvmaGKREVPDPYYESGSkQFDEVLQQCVKCCDAFLDKI
.. .. .|  .|.  ..      ..|||||| . .  |.|||........|.|...
glleakgkvllllefagl...lhwdvpDPyyggle.afeevldlieeaveallell

0042188 Phosphotyrosine protein phosphatases I 6-162 6.9e-39 123.4 In-house 4-143 (146) alignment
Range on Protein: 6-162
Range on HMM: 4-143/146.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
 |.||.||.|||||||.|||.. . |..|     ..|||  . .||.|...|.||. .|...||.  .||||  ...|...||... |||.|..|| ...
kkkvlfvCtgNicRSpmAeallrhllgdr.....vevdSAGtsayhvgepvdpravevlaelgidisghrarqlteedleefDlvltmddsnlrdllplf

RKVPKTERKAE--ILmlgvqdvmagkrEVPDPYYESgsKQFDEVLQQCVKCCDAFLDKI
.. .|.                     .|||||| .  . |.|||... ....|.|...
pgaakgkvllllefw............dvpDPyygg..eafeevldlieeavkallell

LMWPc Low molecular weight phosphotyrosine protein phosphatase 9-159 2.1e-35 112.6 Pfam-A 1-138 (138) alignment
Range on Protein: 9-159
Range on HMM: 1-138/138.0
VLMVCLGNICRSPIAEAVFIDCLKKRgKREEWHVDSSAIIGYhTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARKv
||.||.|||||||.|||.. . |.|.   ... ||| .. ..  |. .| ||. .||. ||.  .||||  | .....||.|. .|......|...| . 
vlfvCtgNicRSpmAeallralleka.lgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape.

pktERKAEILMLGVqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFL
   ...| . .||       ....||||... ...|.||.... ......|
...kkeakvvllge......qwdipDPygke.eeefeevrdeieervkkll

LMWPc Low molecular weight phosphotyrosine protein phosphatase 9-159 2.1e-35 112.6 In-house 1-138 (138) alignment
Range on Protein: 9-159
Range on HMM: 1-138/138.0
VLMVCLGNICRSPIAEAVFIDCLKKRgKREEWHVDSSAIIGYhTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARKv
||.||.|||||||.|||.. . |.|.   ... ||| .. ..  |. .| ||. .||. ||.  .||||  | .....||.|. .|......|...| . 
vlfvCtgNicRSpmAeallralleka.lgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape.

pktERKAEILMLGVqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFL
   ...| . .||       ....||||... ...|.||.... ......|
...kkeakvvllge......qwdipDPygke.eeefeevrdeieervkkll

LMWPc_SSU72_ArsC 7-151 3.2e-33 105.3 In-house 1-126 (126) alignment
Range on Protein: 7-151
Range on HMM: 1-126/126.0
KSVLMVCLGNICRSPIAEAVFIDCLKKrgkreEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIkDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||||||||||.||||. . .||     ...|.| ..  .. || .||||. .||. || ...|..|  . .|...||.|..||..| ... | ..
kkvlfvClgNicRSpmAeavlkkavkk.....glnvsSaGtgaavpgksidsravellkengi.elkhkprqlqeedlkefdliltmdernkdevlellp

KVpkTERKAEILmlgvqdvmagKREVPDPYYESgSKQFDEVLQQC
.   ...| ..|          ...|.|||...  ..| |||...
er..atkkvhll..........nldvkDpyega.esgfeevldli

0047618 Phosphotyrosine protein phosphatases I 7-162 4.1e-33 104.5 In-house 2-136 (137) alignment
Range on Protein: 7-162
Range on HMM: 2-136/137.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIGYHtgkgPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.|||||||.|||.. . |..|     ..|||  . ...    .|.||. .|...||.  .||..  ...|...||... |||...|.|...|.
kkvlfvCtgNicRSpmAeallrhllgdr.....vevdSAGtepag....vdpravevlaelgidisghrskqldeldlpefdlvltmddsalealpllap

KVPKTERkaeilmlgvqdvmagkrEVPDPYYESG-----SKQFDEVLQQCVKCCDAFLDKI
..                      .|||||| .|      . |..||... ....|.|...
aalrlhw.................dvpDPyygggteeekleafervldlieerveallell

0051181 Phosphotyrosine protein phosphatases I 8-160 4.3e-31 97.8 In-house 1-123 (124) alignment
Range on Protein: 8-160
Range on HMM: 1-123/124.0
SVLMVCLGNICRSPIAEAVFIDCLKKrgkreeWHVDSSAIigyHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARk
.||.||.|||||||.|||.. . |..      ..|||  .   |.|. .|.||. .|...||.   .|..  ...|...||... |||.|...| ..|. 
kvlfvCtgNicRSpmAeallrhllgd......vevdSAGt...hpggpvdpravevlaelgidls.lrskqldeldleefdlvltmddsnlcpllplap.

vpkterkaeilmlgvqdvMAGKREVPDPYYESGSKqFDEVLQQCVKCCDAFLD
                  .    .|||||| . .  |.|||... ....|.|.
..................lllhwdvpDPyygglee.feevldlieervealle

0047572 Phosphotyrosine protein phosphatases I 7-160 1.7e-28 89.4 In-house 3-129 (130) alignment
Range on Protein: 7-160
Range on HMM: 3-129/130.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIgyhtGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.||.||||.|||.. . |..|     ..|.|  .     |.|.|.||. .|...||.  .||..  .......||... |||...|.|...|.
kkvlfvCtgNscRSpmAeallrhllgdr.....vevySAGte....gsgvdpravevlaelgidisghrskqldelllpefdlvitmddsalealpllap

KVPKTERkaeilmlgvqdvmagkrEVPDPYYESgSKQFDEVLQQCVKCCDAFLD
..                      ..||||. .  . |.||.... ....|.|.
aalrlhw.................dipDPyggg.leafrevrdlierrvlalle

LMWPc_SSU72 8-160 4e-25 79.3 In-house 2-136 (137) alignment
Range on Protein: 8-160
Range on HMM: 2-136/137.0
SVLMVCLGNICRSPIAEAVFIDCLKkrgkreEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIkDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARK
.||.||..||.||..|||.. . |.      .. |.|  .  .. |. .| .|  ..|. |. . .....  . ....|||... ......... | ...
kvlfVCasNinRSmeAeallkeale......glevkSaGtgslvpgpsidkpaeelykenGl.sikeapeklqeeelekfDlvitleervfdavvedlpe

VPKTERKAEILmlgvqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFLD
  ...||. ..          . ...||..|. ...| ..|... ......|.
rselkrkvhvi..........nvdikDpheea.iegfkaildlieervkella

subfamily_Sponge-LMWPTP-like_pd Subfamily Sponge-LMWPTP-like 9-87 5.1e-06 16.1 In-house 3-80 (173) alignment
Range on Protein: 9-87
Range on HMM: 3-80/173.0
VLMVCLGNICRSPIAEAVFIdclKKRGKREEWHVDSSAIIGYHTGKG--PDSRAMGALKKYGIKDYQHRARVTSPDDFRKF
.|.|| || ||||.|  |     |   .||      ||   .. ||    .| |. |.|    .  . | .  .|  ..| 
llfvcsgnscrspmamivae...kmeaerekiiesdsaagnfkngkfvasqspavnaikaleaeygrtrlkeyepkplkke