Gene Y94H6A.7 in Caenorhabditis elegans

Synonym: CELE_Y94H6A.7, Y94H6A.7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family LMWPTP
Subfamily LMWPTP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP232_AA protein Get Run
CeleP232_AA_5-162 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_LMWPTP_pd Subfamily LMWPTP 6-161 9.4e-64 203.8 In-house 1-151 (152) alignment 
Range on Protein: 6-161
Range on HMM: 1-151/152.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
.|.||.|||||||||||||||. ....|.| .|.|.|||.||  ||.|| ||.||. .|||.|.| . ||||... .||..||||..||..|...|...|
kkkvlfvClGniCrspiaEavlrklvekkglkedwkvdsaaissyhvGkepdkRalsilkkhglkss.hrarqitkedfsefdyilamDesnlkelkkla

RkvPKTERKAEILMLGVQDvMAGKREVPDPYYeSGSKQFDEVLQQCVKCCDAFLDK
.   |.|.||..|.|| .| ..||. . |||| ...|.|..|..|...||.|||.|
k..ekkeskakvlllgeyd.kkgkeiiedpyy.gdekdFeavykqikecckaflkk
0046251 Phosphotyrosine protein phosphatases I 6-162 3.4e-43 137.7 In-house 5-158 (159) alignment 
Range on Protein: 6-162
Range on HMM: 5-158/159.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREE-WHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEI
 |.||.||.|||||||.|||.. . |...|  .  ..||| .. ..|.|..||.||. .||..||.   ||||  ...||..||.|..|||.|..||...
kkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsalhvgeppdpravavlkelgidls.hrarqlteedfeefdlilamddsnlrdllrl

ARKvpKTERKAEILMLGVQDVMAGKREVPDPYYESgSKQFDEVLQQCVKCCDAFLDKI
| .  .. .|  .|.  ....     .|||||| .  . |.|||........|.|.|.
apg..dargkvllllefagllellhwdvpDPyygg.leaFeevldlieeaveallekl
0053360 Phosphotyrosine protein phosphatases I 6-162 8.7e-42 133.0 In-house 5-156 (157) alignment 
Range on Protein: 6-162
Range on HMM: 5-156/157.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
 |.||.||.|||||||.|||.. . |...|  ....|||  . ..|.|...|.||. .|...||.   ||||  ...|...||.|. |||.|.|.|....
mkkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsalhvggpvdpravevlaelgidls.hrarqlteedleefdliltmddsnleellplf

RKVPKTERKAEILMLGVqDVmaGKREVPDPYYESGSkQFDEVLQQCVKCCDAFLDKI
... .. .|  .|.  . ..    ..|||||| . .  |..||........|.|...
pglleakgkvllllefa.gl..lhwdvpDPyyggle.afelvldlieeaveallell
0048765 Phosphotyrosine protein phosphatases I 7-162 1.4e-41 132.3 In-house 3-153 (154) alignment 
Range on Protein: 7-162
Range on HMM: 3-153/154.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRGKREEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.|||||||.|||.. . |...|  ....|||  . .||.|...|.||. .|...||.   ||||  ...|...||.|. |||.|.|.|.....
kkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsayhvgepvdpravevlaelgidls.hrarqlteedleefdliltmddsnleellplfp

KVPKTERKAEILMLGVQDvmaGKREVPDPYYESGSkQFDEVLQQCVKCCDAFLDKI
.. .. .|  .|.  ..      ..|||||| . .  |.|||........|.|...
glleakgkvllllefagl...lhwdvpDPyyggle.afeevldlieeaveallell
0042188 Phosphotyrosine protein phosphatases I 6-162 6.9e-39 123.4 In-house 4-143 (146) alignment 
Range on Protein: 6-162
Range on HMM: 4-143/146.0
QKSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIGYHTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIA
 |.||.||.|||||||.|||.. . |..|     ..|||  . .||.|...|.||. .|...||.  .||||  ...|...||... |||.|..|| ...
kkkvlfvCtgNicRSpmAeallrhllgdr.....vevdSAGtsayhvgepvdpravevlaelgidisghrarqlteedleefDlvltmddsnlrdllplf

RKVPKTERKAE--ILmlgvqdvmagkrEVPDPYYESgsKQFDEVLQQCVKCCDAFLDKI
.. .|.                     .|||||| .  . |.|||... ....|.|...
pgaakgkvllllefw............dvpDPyygg..eafeevldlieeavkallell
LMWPc Low molecular weight phosphotyrosine protein phosphatase 9-159 2.1e-35 112.6 Pfam-A 1-138 (138) alignment 
Range on Protein: 9-159
Range on HMM: 1-138/138.0
VLMVCLGNICRSPIAEAVFIDCLKKRgKREEWHVDSSAIIGYhTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARKv
||.||.|||||||.|||.. . |.|.   ... ||| .. ..  |. .| ||. .||. ||.  .||||  | .....||.|. .|......|...| . 
vlfvCtgNicRSpmAeallralleka.lgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape.

pktERKAEILMLGVqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFL
   ...| . .||       ....||||... ...|.||.... ......|
...kkeakvvllge......qwdipDPygke.eeefeevrdeieervkkll
LMWPc Low molecular weight phosphotyrosine protein phosphatase 9-159 2.1e-35 112.6 In-house 1-138 (138) alignment 
Range on Protein: 9-159
Range on HMM: 1-138/138.0
VLMVCLGNICRSPIAEAVFIDCLKKRgKREEWHVDSSAIIGYhTGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARKv
||.||.|||||||.|||.. . |.|.   ... ||| .. ..  |. .| ||. .||. ||.  .||||  | .....||.|. .|......|...| . 
vlfvCtgNicRSpmAeallralleka.lgdkvevdSAGteal.vgesvdpravevlkekgidisghrarqlseeelkefDliltldeeaarelcpvape.

pktERKAEILMLGVqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFL
   ...| . .||       ....||||... ...|.||.... ......|
...kkeakvvllge......qwdipDPygke.eeefeevrdeieervkkll
LMWPc_SSU72_ArsC 7-151 3.2e-33 105.3 In-house 1-126 (126) alignment 
Range on Protein: 7-151
Range on HMM: 1-126/126.0
KSVLMVCLGNICRSPIAEAVFIDCLKKrgkreEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIkDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||||||||||.||||. . .||     ...|.| ..  .. || .||||. .||. || ...|..|  . .|...||.|..||..| ... | ..
kkvlfvClgNicRSpmAeavlkkavkk.....glnvsSaGtgaavpgksidsravellkengi.elkhkprqlqeedlkefdliltmdernkdevlellp

KVpkTERKAEILmlgvqdvmagKREVPDPYYESgSKQFDEVLQQC
.   ...| ..|          ...|.|||...  ..| |||...
er..atkkvhll..........nldvkDpyega.esgfeevldli
0047618 Phosphotyrosine protein phosphatases I 7-162 4.1e-33 104.5 In-house 2-136 (137) alignment 
Range on Protein: 7-162
Range on HMM: 2-136/137.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIGYHtgkgPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.|||||||.|||.. . |..|     ..|||  . ...    .|.||. .|...||.  .||..  ...|...||... |||...|.|...|.
kkvlfvCtgNicRSpmAeallrhllgdr.....vevdSAGtepag....vdpravevlaelgidisghrskqldeldlpefdlvltmddsalealpllap

KVPKTERkaeilmlgvqdvmagkrEVPDPYYESG-----SKQFDEVLQQCVKCCDAFLDKI
..                      .|||||| .|      . |..||... ....|.|...
aalrlhw.................dvpDPyygggteeekleafervldlieerveallell
0051181 Phosphotyrosine protein phosphatases I 8-160 4.3e-31 97.8 In-house 1-123 (124) alignment 
Range on Protein: 8-160
Range on HMM: 1-123/124.0
SVLMVCLGNICRSPIAEAVFIDCLKKrgkreeWHVDSSAIigyHTGKGPDSRAMGALKKYGIKDYqHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARk
.||.||.|||||||.|||.. . |..      ..|||  .   |.|. .|.||. .|...||.   .|..  ...|...||... |||.|...| ..|. 
kvlfvCtgNicRSpmAeallrhllgd......vevdSAGt...hpggpvdpravevlaelgidls.lrskqldeldleefdlvltmddsnlcpllplap.

vpkterkaeilmlgvqdvMAGKREVPDPYYESGSKqFDEVLQQCVKCCDAFLD
                  .    .|||||| . .  |.|||... ....|.|.
..................lllhwdvpDPyygglee.feevldlieervealle
0047572 Phosphotyrosine protein phosphatases I 7-160 1.7e-28 89.4 In-house 3-129 (130) alignment 
Range on Protein: 7-160
Range on HMM: 3-129/130.0
KSVLMVCLGNICRSPIAEAVFIDCLKKRgkreeWHVDSSAIIgyhtGKGPDSRAMGALKKYGIKDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIAR
|.||.||.||.||||.|||.. . |..|     ..|.|  .     |.|.|.||. .|...||.  .||..  .......||... |||...|.|...|.
kkvlfvCtgNscRSpmAeallrhllgdr.....vevySAGte....gsgvdpravevlaelgidisghrskqldelllpefdlvitmddsalealpllap

KVPKTERkaeilmlgvqdvmagkrEVPDPYYESgSKQFDEVLQQCVKCCDAFLD
..                      ..||||. .  . |.||.... ....|.|.
aalrlhw.................dipDPyggg.leafrevrdlierrvlalle
LMWPc_SSU72 8-160 4e-25 79.3 In-house 2-136 (137) alignment 
Range on Protein: 8-160
Range on HMM: 2-136/137.0
SVLMVCLGNICRSPIAEAVFIDCLKkrgkreEWHVDSSAIIGYHTGKGPDSRAMGALKKYGIkDYQHRARVTSPDDFRKFDYIFGMDDQNIEDLQEIARK
.||.||..||.||..|||.. . |.      .. |.|  .  .. |. .| .|  ..|. |. . .....  . ....|||... ......... | ...
kvlfVCasNinRSmeAeallkeale......glevkSaGtgslvpgpsidkpaeelykenGl.sikeapeklqeeelekfDlvitleervfdavvedlpe

VPKTERKAEILmlgvqdvmagKREVPDPYYESgSKQFDEVLQQCVKCCDAFLD
  ...||. ..          . ...||..|. ...| ..|... ......|.
rselkrkvhvi..........nvdikDpheea.iegfkaildlieervkella
subfamily_Sponge-LMWPTP-like_pd Subfamily Sponge-LMWPTP-like 9-87 5.1e-06 16.1 In-house 3-80 (173) alignment 
Range on Protein: 9-87
Range on HMM: 3-80/173.0
VLMVCLGNICRSPIAEAVFIdclKKRGKREEWHVDSSAIIGYHTGKG--PDSRAMGALKKYGIKDYQHRARVTSPDDFRKF
.|.|| || ||||.|  |     |   .||      ||   .. ||    .| |. |.|    .  . | .  .|  ..| 
llfvcsgnscrspmamivae...kmeaerekiiesdsaagnfkngkfvasqspavnaikaleaeygrtrlkeyepkplkke