Gene ZK484.6 in Caenorhabditis elegans

Synonym: CELE_ZK484.6, ZK484.6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily CeleHP1-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP236_AA protein Get Run
CeleP236_AA_0-125 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_STS_pd Subfamily STS 3-126 2e-40 130.7 In-house 1-150 (245) alignment
Range on Protein: 3-126
Range on HMM: 1-150/245.0
RTIWLVRHGQRVDNVDKKW------------------------KANNDAKWDDPeLTLRGKQQAHEVGKHF--ANMNIEAIVVSPFTRCIETAAQIVAMM
|||..||||.|||.| .||                        ....| |.|.| || ||..||...|...  |...||.|..||..|||.|||.|. ..
rtiyivRhgeRvdevfgkWlksfdegkyerkdlnlpkelprrpdglkdyksDpP.lterGviqAkllgraLleagikiehifcSPslrciqTaaailkgl

ENKAKICVEPGLMEPLYLCKNP-PTIPSMDKIKEYSTQVDESYKPVFEKLP
..|.||.|||||.|.|.|...| |...|....|.. .|.||.||||... .
gkkikikvepgllewlkldrkpipellspeelkkffpqidedYkpvlslse

0051064 Phosphoglycerate mutase-like 1-96 1.4e-25 83.1 In-house 2-95 (241) alignment
Range on Protein: 1-96
Range on HMM: 2-95/241.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPLYLCK
| ....|||||....|.....       | |..|| .|..||...|...|.  ....|...||..|.|.||. | . . ..  .. |.|.|.|  . . 
mmkrlyLvRHGesewnaegrlqg.....wtDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgal

0043909 Phosphoglycerate mutase-like 1-91 5.5e-25 80.7 In-house 1-89 (249) alignment
Range on Protein: 1-91
Range on HMM: 1-89/249.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP
|.....|||||. ..|.....       | |..|| .|..||...|....  .....|...||..|.|.||. | . ...   .. |.|.|.| 
mmkrlyLvRHGetewnaegrfqg.....wlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileelgldklpvevdprLrEr

0048955 Phosphoglycerate mutase-like 4-95 8.4e-25 80.5 In-house 2-91 (240) alignment
Range on Protein: 4-95
Range on HMM: 2-91/240.0
TIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPLYLC
...|||||....|.....       | |..|| .|..||...|...|.  ........||..|.|.||. | . . ..  ...|.|.|.|  . .
rlyLvRHGesewnaegrlqg.....wtDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaealglpllpvvvdprlrErdfga

0036777 Phosphoglycerate mutase-like 1-101 1.2e-24 79.8 In-house 1-122 (247) alignment
Range on Protein: 1-101
Range on HMM: 1-122/247.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP------
|.....|||||. ..|.....       | |..|| .|..||...|.....  ....|...||..|.|.||. | . ...   .. |.|.|.|       
mmkrlyLvRHGetewnaegrfqg.....wlDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiilealglsllpvvvdprLrErdyGale

-----------------LYLCKNPPTI
                 .. .. ....
gltkaeiaekypeelvawwrdpydyrp

0036887 Phosphoglycerate mutase-like 3-96 8.4e-24 76.7 In-house 2-88 (202) alignment
Range on Protein: 3-96
Range on HMM: 2-88/202.0
RTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFANMNIEAIVVSPFTRCIETAAQIVAMMEnkAKICVEPGLMEPLYLCK
....|||||....||....       . |..|| .|..||...|...|.... |...||..|.|.||. |.. ..   ...|.|.|.|  . . 
trlyLvRHGetewnvegrlqg.....dldvpLtelGreqaralgerlaglpfdavysSpllRaiqTaeiiaealg..lpvivdprlrEidfgal

0035570 Phosphoglycerate mutase-like 4-93 4.7e-23 74.3 In-house 1-79 (219) alignment
Range on Protein: 4-93
Range on HMM: 1-79/219.0
TIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEPLY
...|||||....|.....         |..|| ||..||...|...|.  ... |...||..|.|.||. |      . .....|.|.|  .
rlyLvRHGetewnlegrlqg.......dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii......glpveidprLrEidf

His_Phos_1 Histidine phosphatase superfamily (branch 1) 4-106 4.8e-23 74.8 Pfam-A 1-101 (158) alignment
Range on Protein: 4-106
Range on HMM: 1-101/158.0
TIWLVRHGQRVDNVDKKWKANNDakwddPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQiVAMmENKAKICVEPGLMEPLY-LC--KNP
...|||||... | ..... ..|     ..|| .|..||.|.||...  . .|.|...||..|.|.||.. ..  | . .|. ||.| |  .  .  .. 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle.eldipiikeprLrerdfgeweglpk

PTIPSMDK
. .... .
eevkeefp

His_Phos_1 Histidine phosphatase superfamily (branch 1) 4-106 4.8e-23 74.8 In-house 1-101 (158) alignment
Range on Protein: 4-106
Range on HMM: 1-101/158.0
TIWLVRHGQRVDNVDKKWKANNDakwddPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQiVAMmENKAKICVEPGLMEPLY-LC--KNP
...|||||... | ..... ..|     ..|| .|..||.|.||...  . .|.|...||..|.|.||.. ..  | . .|. ||.| |  .  .  .. 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle.eldipiikeprLrerdfgeweglpk

PTIPSMDK
. .... .
eevkeefp

0039931 Phosphoglycerate mutase-like 4-91 1.1e-22 73.0 In-house 1-77 (219) alignment
Range on Protein: 4-91
Range on HMM: 1-77/219.0
TIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEP
...|||||. ..||....         |..|| ||..||...|.....  ... |...||..|.|.||. |      . .....|.|.| 
rlyLvRHGetewnvegrlqg.......dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii......glpveidprLrEi

0037864 Phosphoglycerate mutase-like 1-92 1.5e-22 72.5 In-house 1-95 (211) alignment
Range on Protein: 1-92
Range on HMM: 1-95/211.0
MS-----RTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEPL
||     ....|||||....|.....       | |..|| .|..||...|...|.  ....|...||..|.|.||. | . .     .. |.|.|.|  
MslnllmtrlyLvRHGetewnaegrlqg.....wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiilealglpllpvevdprlrErd





0049178 Phosphoglycerate mutase-like 1-91 6.9e-22 70.7 In-house 2-90 (243) alignment
Range on Protein: 1-91
Range on HMM: 2-90/243.0
MSRTIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIVAMMENK-AKICVEPGLMEP
| ....|||||. . |.....       | |..|| .|..||...|...|  .....|...|| .|.|.||. | . .  .  .. |.|.|.| 
mmtrlyLvRHGetewnaegrlqg.....wtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiilealglpllpvvvdprLrEr

0053607 Phosphoglycerate mutase-like 3-92 2e-20 65.6 In-house 2-80 (191) alignment
Range on Protein: 3-92
Range on HMM: 2-80/191.0
RTIWLVRHGQRVDNVDKKWKAnndakwdDPELTLRGKQQAHEVGKHFA--NMNIEAIVVSPFTRCIETAAQIvammenKAKICVEPGLMEPL
....|||||. . |.....         |..|| .|..||. .....|  .... |...||..|...||. |      . .. |.|.|.|  
trlyLvRHGetewnaegrlqg.......dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii......glpvevdprlrEid

0053031 Phosphoglycerate mutase-like 4-125 1.5e-16 53.8 In-house 6-159 (342) alignment
Range on Protein: 4-125
Range on HMM: 6-159/342.0
TIWLVRHGQR--VDNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM---------NIE--AIVVSPFTRCIETAAQIVAMME--NK---------
.|.||||| |  ... .. .. .   .....||| .|..||.|.|... ..         | .   . .|.. |....|. ..| .   ..         
vivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpilnpllg

---AKICVEPGLMEPL-----YLCKNPPTIPSMDKIKEYSTQVDESYKPVFEKL
    .| .||  ...|     . |..  .. . ..  |.  .. |.|.....||
wqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqkl

subfamily_TFC7_pd Subfamily TFC7 4-124 1.6e-16 51.7 In-house 2-126 (255) alignment
Range on Protein: 4-124
Range on HMM: 2-126/255.0
TIWLVRHGQRVDNVDKKWKANNDA-KWDDPELTLRGKQQAHEVGKHFANMNIE--AIVVSPFTRCIETAAQIVAMMEnkAKICVEPGLMEPLYLCKNPpT
||.. ||| | . ..| ....      .|. |. || .||.|....  .....  ||. ||. ||.||.  |. ..|    . |. |..| .   . |  
tiyiarhGyrsnwlpkgpypdpltgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletskpiaeele..iPvyvdrGvgewykpdrrP.v

IPSM---DKIK-EYSTQVDESYKPVFEK
|.     . ..  . . ... |..   .
ilePasnevlskffPsvisldyestltp

0050036 Phosphoglycerate mutase-like 4-91 1.8e-16 52.5 In-house 2-75 (171) alignment
Range on Protein: 4-91
Range on HMM: 2-75/171.0
TIWLVRHGQRVDNVDKKWkanndAKWDDPELTLRGKQQAHEVGKHFanmNIEAIVVSPFTRCIETAAQIVammenkAKICVEPGLMEP
...|||||. . |.....       | |..|| .|..||. .|...   .. |...|| .|...||. |        .. |.|.|.| 
rlyLvRHGetewnlegrf.....qgwtdvpLtelgraqaralgell...pfdavysSpllRArqTaelil......lpvivdprLrEr

0049226 Phosphoglycerate mutase-like 4-124 2e-13 43.4 In-house 6-158 (342) alignment
Range on Protein: 4-124
Range on HMM: 6-158/342.0
TIWLVRHGQR--VDNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM-----------NIEAIVVSPFTRCIETAAQIVAMMENK-----------
...|.||| |  ... .. .. .    ....||| .|..||.|.|... ..           ..  .  |.. |....|. ..| . .            
vqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpilvplld

---AKICVEPGLMEPLYLCkNPPTIPSMDKIK------EYSTQVDESYKPVFEK
    .| .||  ...| |  .  . | .||.       |.  .. |.......|
wqpipiitepesndtllll.pydscpnfdkllkellkseevqlfleeildllkk

0046349 Phosphoglycerate mutase-like 4-92 2.4e-13 43.1 In-house 10-123 (409) alignment
Range on Protein: 4-92
Range on HMM: 10-123/409.0
TIWLVRHGQRV--------DNVDKKWKANndAKWDDPELTLRGKQQAHEVGKHFANM---------------NIEAIVVSPFTRCIETAAQIVAMMENKA
...|.|||.|         .|.. ..  |   ......|| .|..||.|.||.. ..               ..  .. |.. |....|. ..| .    
vqvlfRHGaRtPtkklsflpnwpginwtn..gpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfppl

KICVE----PGLMEPL
.. .     ..|..|.
ggeivpllrqdlldpp

subfamily_Cele-STS-like_pd Subfamily Cele-STS-like 31-121 1.5e-12 38.3 In-house 49-139 (229) alignment
Range on Protein: 31-121
Range on HMM: 49-139/229.0
DPELTLRGKQQAHEVGKHFANMNIEAIV--VSPFTRCIETAAQIVAMME-NKAKICVEPGLMEplYLCKNPPTIPSMdKIKEYSTQVDESYKPV
|| || .|| ... .|.   .  ||  |   ||  |...||| ..  .  ..|.| |||||.|  |   ..  .|   ..|.    ||| |||.
dpPlteiGkiaskligRaLrdrgiepsvvFCSPdlrsvqtaalllkglGlkraaisvePgLle..yrkarevllppk.afkklgypvdekYkPl

0047369 Phosphoglycerate mutase-like 4-119 1.1e-11 37.7 In-house 47-208 (438) alignment
Range on Protein: 4-119
Range on HMM: 47-208/438.0
TIWLVRHGQRVD---------NVDKKWKANNDAKWDD-------------PELTLRGKQQAHEVGKHFANM-------NIEAIVVSPFTRCIETAAQIVA
...|.||| |           .. .......  ....             ..|| .|..|| |.||.. ..       ..  .  |.. |....|.  .|
vqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrYglLnpedvlyvrssdvdRtlqSAqafla

MME--N-----------KAKICVEPGLMEPLYLCKNPPTIPSMDKIKEYSTQVDES----YK
 .   .            ..| ..|. ...|.   .  . | .|....   . ||     .|
Glfppegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflasdeflelllk

0048946 Phosphoglycerate mutase-like 5-92 1.5e-11 37.0 In-house 45-176 (447) alignment
Range on Protein: 5-92
Range on HMM: 45-176/447.0
IWLVRHGQRV-------------------------------DNVDKKWKANNDAKWDDPELTLRGKQQAHEVGKHFANM--------NIEAIVVSPFTRC
. |.||| |                                .. .. .|..    .. ..|| .|..|..|.||.. ..        .   .  |.. |.
qvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrYlgllpnpseiyvrssdvdRt

IETAAQIVAMMENKA-----KICVEPGLMEPL
...|.  .| . ..      .. . . .... 
lqSaqaflaGlfppepplgyqpipihtvpssn

0049059 Phosphoglycerate mutase-like 4-117 2.1e-11 36.5 In-house 46-200 (435) alignment
Range on Protein: 4-117
Range on HMM: 46-200/435.0
TIWLVRHGQRV--------------------DNVDKKWKANNDA--KWDDPELTLRGKQQAHEVGKHFANM-------NIEAIVVSPFTRCIETAAQIVA
.. |.||| |                      ... ...  ||    ....||| .|..||.| ||.. ..       .   .  |.. |....|.  .|
vqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrYgfLynpdevyvrssdvdRtlqSaqafla

MMENKA------------KICVEPGLMEPLYLCKNPPTIPSMDKIKEYSTQVDES
 . .              .. | .  ..... . .. . | .|....   . || 
Glfppeilgsqllnplnvyqpvpietvdsdndtlpydscpafdellkellasdef

subfamily_TIGAR_pd Subfamily TIGAR 5-90 4.7e-11 34.8 In-house 3-85 (222) alignment
Range on Protein: 5-90
Range on HMM: 3-85/222.0
IWLVRHGQRVDNVDKKWKANNdakwdDPELTLRGKQQAHEVGKHFANMNIEAIVVSPFTRCIETAAQIVAMMEN--KAKICVEPGLME
...||||.   |  |  . .      |  |. .| .||  |.|  .|..|. |. |.  |  .||  |   ..   .... ... | |
livVrhGetefnkekilqgqt.....dtpLsekGveQakrvakrLsnekinyifsSdllRAkqTaeiilkalkekkreaverdkrLrE

0048439 Phosphoglycerate mutase-like 5-84 1e-10 34.6 In-house 13-116 (391) alignment
Range on Protein: 5-84
Range on HMM: 13-116/391.0
IWLVRHGQRVDNVDKKWK-------ANNDAKWDDPELTLRGKQQAHEVGKHFA---------------NMNIEAIVVSPFTRCIETAAQIVAMMENK--A
. |.||| |   .. . |         .  .....||| .|..|..| |...                | ..  .  |.. |....|.  .| . .    
qvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlfpplgl

KICV
.. .
tvil

subfamily_PFKFB_pd Subfamily PFKFB 2-78 2.2e-10 32.3 In-house 6-77 (198) alignment
Range on Protein: 2-78
Range on HMM: 6-77/198.0
SRTIWLVRHGQRVDNVDKKWKANNDakwddpeLTLRGKQQAHEVGKHFANMNIEAIVV--SPFTRCIETAAQIVAMMEN
 |.|.|||||.  .|. ..  ....       || ||...|....|.... |.. . |  | . | |.||  . .  |.
preiylvRhGeseknkkgriggdse.......LterGveyakklakfikeenlkelrvwtselkrtiqTaellglpkeq

subfamily_PGAM5_pd Subfamily PGAM5 3-92 3.8e-10 31.2 In-house 2-83 (189) alignment
Range on Protein: 3-92
Range on HMM: 2-83/189.0
RTIWLVRHGQRVDnvdkkwkannDAKWDDPELTLRGKQQAHEVGKHFANMNI--EAIVVSPFTRCIETAAQIVAMMENKAKICVEPGLMEPL
| . |||||| |.          | . |.  || .|..||...|| ....|.  . .| |  .| .|||  |.  .... |  .   | |  
rhlilvrhgqyvl..........dddsdkkiltelGrrqaeltGkrlkelnlkftklvastmvravetadiiskqlpdvpkktktellreGa

subfamily_PGAM_pd Subfamily PGAM 4-79 7.2e-10 30.6 In-house 2-74 (248) alignment
Range on Protein: 4-79
Range on HMM: 2-74/248.0
TIWLVRHGQRVDNVDKKWKAnndakWDDPELTLRGKQQAHEVGKHFAN--MNIEAIVVSPFTRCIETAAQIVAMMENK
.. |.|||.   | ..|. .     | | .|. .||..|...||   .  .... .. |  .|...|.. |.  ....
klvllRhGeselnkenkfcg.....wvDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTlevileeldqe

subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 4-83 3e-09 27.0 In-house 2-82 (210) alignment
Range on Protein: 4-83
Range on HMM: 2-82/210.0
TIWLVRHGQRVDNVDKkwKANNDAKWDDPELTLRGKQQAHEVGKHFANM--NIEAIVVSPFTRCIETAAQ-IVAMMENKAKIC
 ....|||.   |..   .  .|    |  ||  ||.|| |. .   ..  ..| .. ||.|| ..|. . .. .. .|.  |
kvyiirhgestfnkay..nekvdpylfdarlteegkkqanelsenvekllqdvelvisspltraldttkiallkllkeksikc