Gene ZK938.1 in Caenorhabditis elegans

Synonym: CELE_ZK938.1, CELE_ZK938.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily CelePPP-sf4
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP245_AA protein Get Run
CeleP245_AA_21-299 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 21-300 3.5e-180 590.2 In-house 1-280 (280) alignment 
Range on Protein: 21-300
Range on HMM: 1-280/280.0
SLTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGN
.|..||||||||.|||.||.||.||||||||.||.|||||.|||||||||.|.|.|||||||||||||||||||||||||.||.||||||||.|.|||||
tllacikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgn

HECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVS
||..||||.|||.||.|||||||||||||.|..||||.|..||||.|||||||..|||...||...||||....|||||||||||||..|||..||||||
hevisinrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvs

YIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMREVK
.|||||||||.|||..|||||||||||||||||||||.|||.||||||.|||||.|...|||||||.|||.||||.||||
vifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpalrevk
subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 5-298 2.1e-159 522.3 In-house 4-297 (298) alignment 
Range on Protein: 5-298
Range on HMM: 4-297/298.0
PNFIDKVLSVNdTSNASLTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLM
 ... .||||. .|...||..|||.|.. .||..|.|...|...|||.|||.|||||||||.||||.|....||||.||||||||||||||.||||.||.
dellievlsvs.lsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlll

AYKVRYPNGFFILRGNHECASINRTYGFYDECKRRY-SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWA
||||.||| ||.|||||||..|||.||||.|||||| ||.||.|||..||.|||.|.|.|||.|||||||..|.|..||... ||||.....||.|||||
aykvkypnnffllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwa

DPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMRE
||||...|| .||||||..||..||||..||..|||..|.||||||||||||.|.||||||||.|||.|||.|..|.|||.|..|||.|||...|
dpenavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpekke
subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 3-300 3.5e-133 436.4 In-house 2-299 (299) alignment 
Range on Protein: 3-300
Range on HMM: 2-299/299.0
NIPNFIDKVLSVNdTSNASLTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICL
.. ... |.|.|   |. .||...|| ..  . . .|...  ||...||.||| |||||||||.||||||.. .|||| |.||||||||||||.||.|.|
dvdellskllnvg.msekrltksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitl

LMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRY-SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLL
|...|..||. ||.||||||| .||| ||||.||..|| |  |.  ||. |. .||. .|..||.||||||||.| .  || .. || ||||  | .|||
llcfkikyperffmlrgnhecpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidll

WADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMREVK
||||..   .|  | |||||.|| .||.|  ....|||.|| ||||||||||||.|.||||||||.|||.||| | || ||| |. .| .|||. ...|
wadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpkslk
subfamily_PPP1C_pd Subfamily PPP1C 23-296 1.1e-128 421.3 In-house 7-280 (282) alignment 
Range on Protein: 23-296
Range on HMM: 7-280/282.0
THCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHE
.  .|||.|  .... ..|| .|....|..||. ..|||||||.||||.|... .||..||||||||||||.| ||.|.||.|||..||. .|.||||||
evklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhe

CASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYI
.|||||.||||||||||||  |.. |.. || |||.|... .|.|.|||||||| |  |. || || . |.  |..||||.||.....||..|.||||. 
sasinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsft

FGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAM
||..||..| .|...||| |.||||.|||||||...|||.||||.|||||||..... |||.|..||.||||| 
fgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkpak
PP2Ac_SM00156 28-295 9.6e-113 368.7 In-house 3-270 (271) alignment 
Range on Protein: 28-295
Range on HMM: 3-270/271.0
EADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASIN
. ..  ..||.|.||......|||.||. |.||||||..||||....  .||...|.||||||||| |..|||.||.|.|..||. ...||||||. |.|
keevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvn

RTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANV
..|||..|.||.|.  .|..|...|..|||.|... .|.|||||||||| |. ...|. |. ..|. .|..||||.|||... |. ...||.|..||...
kiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFgeda

VKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
||.| .|.|..|| |.|.||..||||||||.||||||||.||.||.| | .. |.. | .|.| ||..
vkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlkeq
subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 26-297 7.2e-109 356.6 In-house 3-276 (284) alignment 
Range on Protein: 26-297
Range on HMM: 3-276/284.0
IKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECAS
|   |.. .. .. .|.  |  ..||..|| .|||||||..||||.|..  ||   ||||||||||||.. || | ||.|||| .|| ||.|||||||. 
ippedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecsl

INRTYGFYDECKRRYSL-ALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPN-ACLAMDLLWADPENNHTGWGKNSRGVSYIF
||. ||||.||.|||   ..|  |. .|  .|| |..  ||.|||||.|  |   .||  | |||| |.   ||.|.||.|| | . ||  |||||||.|
inkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvf

GANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMR
|.. .. . ....|||. | ||||||||||||..||||||||| |||.||| | .| |.. |. || .|.|  .
gsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlrprkk
subfamily_PPZ_pd Subfamily PPZ 2-294 4.7e-107 350.9 In-house 1-293 (300) alignment 
Range on Protein: 2-294
Range on HMM: 1-293/300.0
VNIPNFIDKVLSVNDTSNASLTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVIC
|.| . |.|.|    ... .   |.|...|  .  ...... || ...|.  .. . ||.||||.||||.| .| |||  ||||||||||||.| || | 
vdideiiqklldagyaakrtknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletil

LLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLL
||..||..||. ||.|||||||| . | ||||||||||  . ... | . ||.|||.|...|.|||.|||||| | |  .. ...|| | |.  |  |||
lllcykikypenffllrgnhecanvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindll

WADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKP
|.|| ..   |  | ||||| .    .. | .|. .||..| | ||.|||||| |. |||.||||.|||||||   .| | | |. |||.| |
wsdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelldp
0045823 Metallo-dependent phosphatases 24-299 1.8e-106 349.5 In-house 41-328 (473) alignment 
Range on Protein: 24-299
Range on HMM: 41-328/473.0
HCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHEC
  ..| |.  ...|.|.||. . ...|....|.|.||||||..||||..... |||.....||||.|||| . |||..||.|.|..||. .|.||||||.
gllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHEl

ASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPeNNHTG--------WGKN
. .|  |||.||. ..|.  ||.||.....||||.| | |.|...||||||.| .. |...| ||...|. .|..||||.||  .  |        .| .
rllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.weddgdgllrlrffgns

SRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKR------LVTIFSAPKYCGEFDNNAGIMIVDERLiISFEILKPAMREV
 ||..|.||...|..| .|...||| |||..|..|||.. |..      ..|.|||| |||...| |.....|| | ||| ...|.  ..
prgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphpl
subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 6-295 1.3e-104 342.7 In-house 4-295 (297) alignment 
Range on Protein: 6-295
Range on HMM: 4-295/297.0
NFIDKVLSVnDTSNASLTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMA
. |  |||   | .  |.. | |  .  ... . |.. || .||||.||| ||||||||. ||||.| |  .||  |||||||||||||  .| | ||.|
siiidvlsa.sthekllskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivllla

YKVRYPNGFFILRGNHECASINRTYGFYDECKRRY-SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSP---ELVSWTQLAKIIRPFDPPNaCLAMDLL
|||..|  .|.|||||||  .|..||||.||..|| |. .|  ||..|| |||. .|. .|.||||||||   . ..   | || |. .  .  |  |||
ykvkfpgnlfllrgnhecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkierstegke.rlvadll

WADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
||||    .|. .| ||    || . | .   ....||..| |||||||||||| ..||||||||.|||.||| | .| .||.|  |||||.|.
wadpisglsgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilrpt
subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 27-295 8.2e-103 336.7 In-house 9-283 (284) alignment 
Range on Protein: 27-295
Range on HMM: 9-283/284.0
KEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFP------PDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGN
|| ..  .   .....  .   .|..||. ..||||||. ||| ...   .|       ...|||||||||||   .||| ||.|||...|.  |.||||
kekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfllrgn

HECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVS
||   .|. |||| |||.||| |||. ||  ||..||||..| .|.|||||.| .|.. .|| |. ||.| |.  .  || |||||.. .|. .  ||  
hesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesprgag

YIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
 .|||. ||.|..|...||. | ||||.||||||||..|||||||| |||..|| | .. ||| |..|| .||| 
kvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlkpd
0049330 Metallo-dependent phosphatases 22-296 9.7e-103 336.4 In-house 26-300 (309) alignment 
Range on Protein: 22-296
Range on HMM: 26-300/309.0
LTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNH
 .....| ..  .....|.||  . ...|....|.|.||||||..||||..... |||.....||||.|||| . |||..||.|.|..||...|.|||||
klkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllypdnvfllrGNH

ECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSY
|.. .|. |||.||..|.|.  |..||.....||||.| | |.|.|.||||||.|... |.... ||...|.  | .||||.|| . . |...| ||...
ElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpiregfapnprglgv

IFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAM
.||...|..| .| ..||| |||..|..||..|.|..|.|.||||.|||...| ......|| | ||| ...|. 
vfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvp
subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 23-297 2.8e-102 334.5 In-house 7-284 (287) alignment 
Range on Protein: 23-297
Range on HMM: 7-284/287.0
THCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHE
...... ||  |.|. ..||    ...||.|||...||||||. ||||||| .  .|. .||||||||||| . |||. ||...|..||.   .||||||
ldafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhe

CASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPfDPPNAC---LAMDLLWADPENNHTGWGKN-SRG
.  ||..|||..| ||...  ||..|...|. |||||..| ||.|||||.||.| |. .|  . .|   | ||   | .||||||||..  .   |  |.
vkkinklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkp.ttplacdeglqvdllwadpekdaktfelnkira

VSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMR
.| .|| ..| |. .|..|||| | |.|...||.|..||||||.||||.|.||  | . .. |.. | .||  |||   
isvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpedf
PPP_3 26-293 4e-101 330.6 In-house 2-270 (271) alignment 
Range on Protein: 26-293
Range on HMM: 2-270/271.0
IKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECAS
..| ... .....|.||. ....||..||. ||||||||..|||..|. . ..|...||||||||||| . |||..||.|.|..||. ...||||||...
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq

INRTYGFYDECK-RRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFG
||..|||..|.. ....  .|...|..|. |||.|.|.......||||||.. |. |. |. |. . |. .. .|||. .......|.....||....||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg

ANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILK
..|...| ||....||.| |.....|||...|...||.||||.||....| . |. ..|.|  .|..|.
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 28-295 4.1e-97 317.8 In-house 10-277 (281) alignment 
Range on Protein: 28-295
Range on HMM: 10-277/281.0
EADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASIN
. .|  || | . |.| . ..||...||.| ||.|.|..|| |.|.  . .|.. ..||||||||| | |||. ||...|.||..  ..|||||| ||.|
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvn

RTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANV
. |||| ||. .|   |. .||. || ||. |.|. |. ||||||||||..  .| .. .| ....  | .|||||||.|.  .| . |||.|..|| ||
kiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGknv

VKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
|.|   .....|| |.||||||||| .. ..|.|.||.|.||  . | | .. ||| | ||.  | ||
vddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpa
PPP_1 28-279 1.7e-96 315.6 In-house 3-262 (264) alignment 
Range on Protein: 28-279
Range on HMM: 3-262/264.0
EADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASIN
|. .  .... |..|. . ...||...| ||||||||..|||..|. . ..|..|||||||||||| . .|...||.|.|..||. .|.||||||.....
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt

RTYGFYDECK-RRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLL-------WADPENNHTGWGKNSRGV
..|||..|.. ..||  .|. ....|. |||.|.| ..|...|||||||| .  |  |. |  . |. . ..|||       . |........ .. ||.
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa

SYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIM
.|.||..|...| .| |..||.| |.|...||||......||||||. |. |..|.. ..
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayv
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 81-295 1.7e-96 316.1 In-house 101-315 (317) alignment 
Range on Protein: 81-295
Range on HMM: 101-315/317.0
QNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWT
..|||||||||||   .||. ||.|.|..||.  |.||||||  ..|. |||| |.|.||| |||. ||. || |||||... .|.|||||.| ||.. .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMI
|| |. ||.| |.  .  || ||||... .|. . .|| . .|||. ||.|..|...||. |.||||.||||||||..||||||||.|||..|| | .. 
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDERLIISFEILKPA
||. | ||...|.| 
vdkklkisinvlrpe
0053225 Metallo-dependent phosphatases 23-295 8.9e-96 313.6 In-house 19-291 (293) alignment 
Range on Protein: 23-295
Range on HMM: 19-291/293.0
THCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHE
. ...| ..  ...|.|.||. . ...|....|.|.|||||...|||...... |||. ...||||.|||| . |||..||.|.|..||.....||||||
lkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkllypdnvvllrGNHE

CASINRTYGFYDECKRRY-SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPEnNHTGWGKNSRGVSY
.. .|  |||.||..|.| . .|..|......||||.| | |.|...||||||.|... |...| ||...|.  | .|||| ||    .||... ||...
lmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.lwsgwlpsyrglgv

IFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
.||...|..| .| ..||| ||||||.|||... |..|||.||||.|.|...| ......|| | ..| ...| 
vfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapv
subfamily_PPP4C_pd Subfamily PPP4C 23-295 8.1e-88 287.4 In-house 13-285 (288) alignment 
Range on Protein: 23-295
Range on HMM: 13-285/288.0
THCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHE
.. ||| ..  . .. ..||  .. . .|..|. ||||||||. |||..|.     |..|||||||.||||   .| . ||.|.|||||.   ..|||||
celikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhe

CASINRTYGFYDECKRRY-SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHtGWGKNSRGVSY
. .| ..||||||| |.| | ....   ..|. |.|.|.| |.|||.||||||.. .  ..  | |  . |.     ||||.|||. . ||.   ||  |
srqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae.gwavsprgagy

IFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
.||..||..|.|. .|.||.| ||.|..|| .  .....|..||| ||    | | |. .||.|   |.|.. |
lfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa
subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 29-294 3.6e-87 285.4 In-house 9-274 (280) alignment 
Range on Protein: 29-294
Range on HMM: 9-274/280.0
ADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINR
 .|  .|   . |.  .. ..| .||| | |||| || |. |.|.     |... .||||||||| | .||. ||.. |.|| .  ..||||||  |.|.
heiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnk

TYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANVV
 |||| ||. .| ..|. .||. || .|....|| |..||||||||||.    . .| || .| .  | .||||.|| |.  || .. ||.||.||  ||
iygfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisymfgkgvv

KDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKP
..  . ..|||| |.|||||||||..| .||.|.|| |.|| .| | | .....  | .||. | |
eqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqlip
subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 22-296 5.7e-87 284.4 In-house 12-290 (290) alignment 
Range on Protein: 22-296
Range on HMM: 12-290/290.0
LTHCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNH
 ...... ||  ..|. ..||    ...||.|||.. ||||||  .||| |.   .||. ..|||||||||| . |||  ||. ||.||..   .|||||
vldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnh

ECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPP--NACLAMDLLWADPEN--NHTGWGKNSR
|.  .|| |||..|  |. .  |.. .|..|. |.||| .. .|.|||||.|... ||  |  . .|  |   .  | .|||||||..  ..|   .  |
evrkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqr

GVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAM
..| .|| ... |. .|. ..|| | |.| ..|..|  ||.|||.|||| |.|.  |   |. | | | .|. .||| .
aisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvlkprk
subfamily_PPP2C_pd Subfamily PPP2C 24-298 7.7e-87 284.1 In-house 15-289 (290) alignment 
Range on Protein: 24-298
Range on HMM: 15-289/290.0
HCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHEC
. ..|...  ..|. |.||| .. . ||..|..||||.|||. ||| .|.     || ||||||||||||   .| ..||.| ||||..   ||||||| 
kqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvrykeritilrgnhes

ASINRTYGFYDECKRRYSL-ALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPEnNHTGWGKNSRGVSYI
  | . ||||||| |.|.  .... | .||. |||.|.. ..|||.||||||.. .  .. .. |  . |.     ||||.||. . .|||   ||  | 
rqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.drggwgisprgagyt

FGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMRE
|| .. ..| .. .. |||| ||.| .||..  |...|||||||.||    |.|.|. .|..|  ||   .|| |.
fgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 48-300 2.5e-80 262.9 In-house 2-261 (263) alignment 
Range on Protein: 48-300
Range on HMM: 2-261/263.0
MVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSL-----
..|.|||| .||| |||| ||||||| |      .||||||||||| . |||| ||.. |.  |  ...||||||  .||. |||. | |.|.       
llelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevye

ALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPN-ACLAMDLLWADPENNHTGWGKNS-RGVSYIFGANVVKDFTEKMNIDLI
..|| |...|. .||||..| ||.|||||.|| | |  ..  |  |..  .   || ||||||||..  |.  |  | .| .|| . | |. ....||||
svynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidli

ARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMREVK
 | ||||. || ||||.||.|.||| .|  |. | | ...|.. | .||  |||   ||.
vrahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlkpedfevr
subfamily_PPP6C_pd Subfamily PPP6C 24-286 1.4e-78 257.0 In-house 13-275 (290) alignment 
Range on Protein: 24-286
Range on HMM: 13-275/290.0
HCIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHEC
. . |.|.  . .  .|.|. ..... |..|..||||||||. ||. .|.     ||..|.||||.||||   || . .|.. |..||.   .||||||.
kylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhes

ASINRTYGFYDECKRRYSLA-LYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNhTGWGKNSRGVSYI
  | . |||||||...|  |  .. . ..|. |...|.| ....|.||||||..    |.  | |  . |.     ||.|.|||.    |   .||  |.
rqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedv.etwavsprgagyl

FGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLI
||..|.|.|..  |..||.| ||.|..|.... |..|||..||| ||    | | |.....   
fgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaee
subfamily_PPP5C_pd Subfamily PPP5C 34-285 2.5e-77 253.0 In-house 42-299 (322) alignment 
Range on Protein: 34-285
Range on HMM: 42-299/322.0
VIEECKDILSAQATMVEVQAP----IAVCGDIHGQYTDLLRIFNRCSFPP-DQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINR
.. | |..|......||.. .    ..||||||||. ||| ||.    |  .. ||| ||.||||   .||| .|...|. ||| ||. |||||  ..|.
illeakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnk

TYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGL-SPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNhTGWGKNSRGVSYIFGANV
 ||| .|.| .|. .... |...||.|||. .|  ... .|||| | . |.  .| || |  .||.  | ..|||.||... .| .. .|||.  || .|
lyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqea.nGrspskrGvgvqfGpdv

VKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIV-DERL
 | | .. |..|| | |.| ..|||.  | .|.|.|||| || . .| .... . .. |
tkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddl
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 82-299 1.5e-76 250.7 In-house 121-338 (339) alignment 
Range on Protein: 82-299
Range on HMM: 121-338/339.0
NYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQ
 |||||||||||   .||. || | |. ||.  ..||||||  |.| .|||| | . ||   ||. |||.|| .|.||.|   |.|||||.|  | |. |
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq

LAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIV
.. . ||.. |.  .  || ||||.    |.   .|| |..||   .. | .|...... ||||||.||||||  .|||||||||.|||. || | .. .
fsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfsi

DERLIISFEILKPAMREV
|..| || ....|  |. 
dkklkisinvfrpesrdk
subfamily_PPP3C_pd Subfamily PPP3C 26-284 2e-75 247.3 In-house 41-312 (452) alignment 
Range on Protein: 26-284
Range on HMM: 41-312/452.0
IKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECAS
..|...  .|||. ..|. . |..||.|||.|.||||||. |||..|.    | ...|||||||||||   .|..  |.| |. ||. .|.|||||||  
leeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrh

INRTYGFYDECKRRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTG------WGKN-SRG
.   . | .||| .|| ..|... . |.|||| |.. .. .|.|||||||. |  .. |. |  .||.  .  ||||.|| ...        . .|  ||
lteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsvrG

VSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFAD------KRLVTIFSAPKYCGEFDNNAGIMIVDER
 ||... . | .| .| ..  | | |.. ..||. . .        |.|.|||| |.. ..| | .. ... 
csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn
subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 24-298 7.4e-73 238.4 In-house 19-295 (307) alignment 
Range on Protein: 24-298
Range on HMM: 19-295/307.0
HCIKEaDIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHEC
.  || ... || |.. |.|.. ..|... |  | ||.|||. ||. .|     ||.  |.| |||||||   ||.| ||..||. ||.   .|||||| 
qytke.efenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnhei

ASINRTYGFYDECKRR---YSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPENNHTGWGKNSRGVS
| .|. ||||.||          ..  ||  || ||. |.|. .|.|||||||| |    .| .  .|   |   .  |.|||||.     |   |||  
arvnkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsg

YIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPAMRE
. ||.||. |   .. ..|| | ||.. |||  .. ..|.|||||| ||  . |   .. ||| | |    . |.  .
ftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpesen
subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 28-294 1.1e-72 237.7 In-house 8-299 (302) alignment 
Range on Protein: 28-294
Range on HMM: 8-299/302.0
EADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRC------------SFPpDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFF
. ..  .||.  . |. . |..|. .|... ||||||. ||.||.|              ||   . ..|||||||||.. .| |||..|.|| ||. . 
ksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfs.sdkfvflGdyvdrGsksieciclvfalkvlyptnyi

ILRGNHECASINRTYGFYDECKRRYSLA----LYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDP-PNACLAMDLLWADPENNH-
.||||||. .|| .||| .| . |.. .    ....|.. |  .|| |..  .|.|.|||.|| | |. .. || ||.    .  || |||.||| . . 
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvql

-------TGWGKN-SRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKP
         . ||  ||.|..|    |.|. ...|..|| |.||..  |. |||||.|.||||||.|  | ||.  .. ||    .|  .|..
laavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlrn
subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 27-293 2.3e-72 236.7 In-house 8-299 (302) alignment 
Range on Protein: 27-293
Range on HMM: 8-299/302.0
KEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRC------------SFPpDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGF
.. ..  .||.  . |. . |..|. .|... ||||||. ||.||.|              ||   . ..|||||||||.. .| |||..|.|| ||. .
sksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfs.sdkfvflGdyvdrGsksieciclvfalkvlyptny

FILRGNHECASINRTYGFYDECKRRYSLA----LYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDP-PNACLAMDLLWADPENNH
 .||||||. .|| .||| .| . |.. .    ....|.. |  .|| |..  .|.|.|||.|| | |. .. || ||.    .  || |||.||| . .
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq

--------TGWGKN-SRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILK
          . ||  ||.|..|    |.|. ...|..|| |.||..  |. |||||.|.||||||.|  | ||.  .. ||    .|  .|.
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngklsisvlr
PPP_2 55-246 3.3e-72 235.3 In-house 1-197 (198) alignment 
Range on Protein: 55-246
Range on HMM: 1-197/198.0
IAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECK-RRYSLALYNEFQNLFN
. ||||.|||..|||..|. . ..|...|||||||||||.. |||..||.|.|..||. ...||||||....|..|||..|.. .... ..|...|..|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe

SLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLL----WADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQV
 |||.|.|.......|||||.|. ...|  |. |. . |. .. .|||    . ||....... ...||....||..|.....||....|| | |.|
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
subfamily_PPG1_pd Subfamily PPG1 26-295 2.9e-71 233.2 In-house 14-296 (300) alignment 
Range on Protein: 26-295
Range on HMM: 14-296/300.0
IKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECAS
. |. .  ...  |..|  .. ..|...|..| ||.|||. |.| ||.     || ||||||||||||   .| | ||.. |.|||    .||||||   
lpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrq

INRTYGFYDECKRRY--SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPPNACLAMDLLWADPE--NN-------HTG--W
| ..|||| || |.|     ... . ..|. | |.|.|   |.|.||||||.  |  |.  . |  . ||     ||||.|||  ||       . |  .
itqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhf

GKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLIISFEILKPA
 .  ||  | .| .||. | .. ... | | ||....||. . |..| |..|||.||    | | |. . |..   |.. . |
vvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeea
PPP_4 55-246 2.2e-69 226.4 In-house 1-196 (197) alignment 
Range on Protein: 55-246
Range on HMM: 1-196/197.0
IAVCGDIHGQYTDLLRIFNRCS-FPP-DQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRRYSLALYNEFQNLF
. |.||||||..||| .. ... .|. ...|.||||||||| . |||..||.|.|..||. ...||||||..|.|. |||..|......  .....|..|
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdvf

NSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPP-NACLAMDL-LWADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQV
. |||.|.|.......|||||.|| |.... .| |... | . ....|| ||.||.....|. .. ||....||..|...| || |..|| |.|..
dllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
PPP_5_Dcr2 55-247 6.1e-68 221.7 In-house 1-199 (199) alignment 
Range on Protein: 55-247
Range on HMM: 1-199/199.0
IAVCGDIHGQYTDL-LRIFNRCSFPP-DQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYGFYDECKRR-YSLALYNEFQNL
. ||||.|||. || |..|... .|. ...|.|||||||||...|||..||.|.|..||. ...||||||. ..|. |||..|.... ..  .|. ....
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv

FNSLPLCAMISGRIFCMHGGLSPELVSWTQLAKIIRPFDPP-NACLAMDL-LWADPENNHTG-WGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVV
|. |||.|.|.......|||||||. |...|.|| |... | .    .|| ||.||.....| . .. ||....|| .|...| || |..|| |.|...
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk
subfamily_PPPLV_pd Subfamily PPPLV 36-284 4e-53 173.6 In-house 7-278 (290) alignment 
Range on Protein: 36-284
Range on HMM: 7-278/290.0
EECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRI---FNRC-SFPPDQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRTYG
.   ||| |.  ..|...|. | ||.||.| ||  .   . |        ..||||||||||   .|.|. |.| || ||  ...||||||  |.  .. 
dvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesie

FYDECKRRYSLAL---YNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLAK---IIRP--FDPPNACLAMDLLWADPENN-----------HTGW
.. |.. ..   |   .. |.| |. ||| |.|  ..||.|.|.     . ....    |.     |   | ||.|.||.||...             |.
ykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvlneGf

GKN-SRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEfDNNAGIMIVDER
 .| .|| ...|... .. | .. |.. . | |.| . |...  . ||.|.||. .|||   |.| ...||..
vdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGs.sneaalilvdkk
Metallophos Calcineurin-like phosphoesterase 54-247 2.7e-42 138.3 Pfam-A 2-199 (200) alignment 
Range on Protein: 54-247
Range on HMM: 2-199/200.0
PIAVCGDIHGQYTDL----LRIFNRCSFPPDQNYLFLGDYVDRGRQQLEVICLL--MAYKVRYPNGFFILRGNHECASINRTYGFYDECK----------
.|.|.||.||.. ||    |.... .. .. ...|||||.||||.  .|...||   ..|...|. .| ||||||. ..|  |||..|.           
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange

------------------------RRYSLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSPELVSWTQLakiirpfdppnaclamdllwadpennhtgwg
                         ..    . |... |. |||.| . |.|...||.||... |...                                
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................

knsrgVSYIFGANVVKDFTEKMNIDLIARGHQVV
      |. || ... .. || ..||. |||. .
.....gselfgpdalekllekygvdlvlrGHtHk
subfamily_PPP7C_pd Subfamily PPP7C 35-184 5.3e-36 117.1 In-house 42-198 (383) alignment 
Range on Protein: 35-184
Range on HMM: 42-198/383.0
IEECKDILSAQATMVEVQ----APIAVCGDIHGQYTDLLRIFNRCSFPP-DQNYLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNHECASINRT
. |.|..| .   . .|.      ..||||.||.  ||| |. .  .|  ...|.| ||.||||.. .|....|.|. . ||. ... |||||   .|  
lreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalllvypkevylnrGnhedhilnlr

YGFYDECKRRY---SLALYNEFQNLFNSLPLCAMISGRIFCMHGGLSpELVSWTQLAK
|||  | . .|   .  . . ....|  |||...|  .|. .|||.| .  . . | |
yGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis.dktdlelldk
subfamily_PPP7C_pd Subfamily PPP7C 198-276 1.8e-17 56.2 In-house 238-316 (383) alignment 
Range on Protein: 198-276
Range on HMM: 238-316/383.0
MDLLWADPENNHTGWGKNSRGVSYIFGANVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNA
.|.||.||....  .    ||    ||..| |.. .| |..|. | |.  ..||||  ||...|||||  |  |  |  
ldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrG
subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 25-78 1.8e-09 30.2 In-house 8-61 (317) alignment 
Range on Protein: 25-78
Range on HMM: 8-61/317.0
CIKEADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFP
 .||...  .    ....  .  ..|..||....||||||. ||| ...   .|
lfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwp
subfamily_YNL217W_pd Subfamily YNL217W 55-175 1.5e-08 27.4 In-house 12-139 (235) alignment 
Range on Protein: 55-175
Range on HMM: 12-139/235.0
IAVCGDIHGQYTDLLRIFNRCSFPPDQN--YLFLGDYVDRGRQQLEVICLLmaykvRYPNGfFILRGNHECASIN------RTYGFYDE--CKRRYS--L
. | ||.|| | .|.....      |.|   ...|| ...| ...||. ..     |  ..   ..|||| . .       .  |. .    ..     .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv.....rkdqv.kcvkGnheelvllaykwvkkpkgaeplefsskfsfles

ALYNEFQNLFNSLPLCAMISG-RIFCMHGGLSPE
.| ..  ..  .|.    |..  .. .|.||.| 
klskadmeyarelgfsldipsdellvvhaGlvpg
subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 29-78 1.7e-06 20.4 In-house 14-63 (339) alignment 
Range on Protein: 29-78
Range on HMM: 14-63/339.0
ADIDGVIEECKDILSAQATMVEVQAPIAVCGDIHGQYTDLLRIFNRCSFP
|..  .   ..... ..  .....|||.| ||||||. ||| ...   .|
aelaelchrareliwsepiflkleapicvmgdihgqfddllamldmngwp