Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPG1_pd | Subfamily PPG1 | 8-294 | 1.6e-186 | 611.6 | In-house | 1-299 (300) | alignment | ||
Range on Protein: 8-294
Range on HMM: 1-299/300.0
LDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPS
||.|.|||||.|.|||.|.||.|||.||||..||||.||||||||||||||||||||||||||||.|||||||||||||||..||||||||..|||||||
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps
RITLLRGNHESRQITQVYGFYGECMRKY-GNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPD----
|||||||||||||||||||||.||.||| ||..||||.||.||||..||||||.|||||||||||.||||||||||||.||||||||.|.|||||.
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn
-----PDREG--FVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQS
||||| ||.|||||||||||||...||.||.|..||||||||..|||.||||||||||||||||.||||.|||.|..||.|||||.|..||.|
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeapes
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 6-294 | 5.6e-162 | 530.7 | In-house | 2-289 (290) | alignment | ||
Range on Protein: 6-294
Range on HMM: 2-289/290.0
FNLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRY
.||..||||..|. | ||..||...|.||.| .||||||...||||.|||||||.|.||.|||||..||||||||||||||||.||||..||..||.||
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry
PSRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDpDR
..|||.|||||||||||||||||.||.|||||..||||||..||||...|..||.|.|.|||||||. ..|.|. |||.||||.||.|.|.|||||| ||
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpd.dr
EGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQS
.|.. |.|||||..|||.. .| ..|....|.|||||.|.||....|....|..||||||.||||.|.|.|...||...|.....||..
ggwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 7-293 | 3e-133 | 436.5 | In-house | 2-287 (288) | alignment | ||
Range on Protein: 7-293
Range on HMM: 2-287/288.0
NLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYP
.||. ||||..||.. |...|.. |..|.|. |||||.. ||||| ||.||||||.||.||.||..|.||||||||.||||..||||. || .||.|||
dldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvryp
SRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDpDRE
||||.|||||||||||||||| ||.||||. .||.| ||.|||||.|||||. |.||||||||| ..|.|...|| ||||.||.|.|.|||||. | |
dritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe.dae
GFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQ
|. | ||||| .|.||. .| ..|... |.||||| |.||. |..|. ||||||||| ||||.|.|.|..|.|.. |. . ||..
gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaaa
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 8-294 | 7e-130 | 425.3 | In-house | 2-287 (290) | alignment | ||
Range on Protein: 8-294
Range on HMM: 2-287/290.0
LDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPS
||. || .||. |||. .|.. |....||. ||||| ..|||||.||.||||||..|.|. ||| |||.|.||||.|||||.|.||...| .||..||.
ldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypd
RITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDpDREG
||||||||||||||||||||| ||..|||| ..|||.|..|| |..|||||| . |||||||| .|||.|..| ||.|..||..|..||||. | |
ritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpe.dvet
FVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQS
.. |.||||| .|. || |...|... |.||||| ..|.. ||.|| ||||||||| ||||.|||...... || .. . | |..
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpde
|
|||||||||
PPP_3 | 21-288 | 1.3e-114 | 374.8 | In-house | 2-269 (271) | alignment | |||
Range on Protein: 21-288
Range on HMM: 2-269/271.0
LPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQ
|.|...||...|.||.| .|||..||..||||.||.|||..|.||.||.||..|.|.|||||||||||..|.|.. || .||..||....||||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
ITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYG
|..||||. |...|.|. .|.|...|.|..|..||.||| ...|||||||| |.|||| |.|..|||.||.| | |.|... ..||. .|.||||. .|
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg
KDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTY
.||| .||..||.. |||||.|...||..|.|.|. ||.||||||.|..|...|....|.|.. |...
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkql
|
|||||||||
0045823 | Metallo-dependent phosphatases | 4-295 | 1.5e-111 | 366.3 | In-house | 26-328 (473) | alignment | ||
Range on Protein: 4-295
Range on HMM: 26-328/473.0
STFNLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKL
. ..|| .|| | |...|||...... |..||.| .|.|..|. ...|.||.|||..| |..... | |.....||||.||||..|.|.. || .||.
glldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalki
RYPSRITLLRGNHESRQITQVYGFYGECMRKYgNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPdP
.||....|||||||.|.....|||..|...|| . ....| | ...| .||.|.. |..|||||||. ..|||. ..|..|.|..|.| |.|||||
kypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdP.w
DREG--------FVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNK------LSTVWSAPNYCNRCGNMASIVEVNEKLeRYFNTYA
. .| |. |.||||| .|.|.. .||..|....|.|.|. ...||. |||.| . ||.||||||.|.|| |......|.| ..| ..
eddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfd
AAPQSL
..|. |
psphpl
|
|||||||||
0049330 | Metallo-dependent phosphatases | 7-293 | 1.3e-107 | 352.4 | In-house | 16-301 (309) | alignment | ||
Range on Protein: 7-293
Range on HMM: 16-301/309.0
NLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYP
.|| .||.| |. .|.|...... .|.||.|.||.|..|. ...|.||.|||..| |..... | |.....||||.||||..|.|.. || .|||.||
lldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalkllyp
SRITLLRGNHESRQITQVYGFYGECMRKYGnPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDRE
....|||||||.|.....|||..|..|||| . .|..|......| .||.|.. |.||||||||. |..|||. |.|..|.|..| | |.|||||.|.||
dnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpire
GFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQ
||....||.|. .| ... |||. |....|||.|.....||.|.||.|| ||.||||||.|.||.....|..|.|...| .. ..|.
gfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpl
|
|||||||||
PP2Ac_SM00156 | 23-289 | 1.5e-106 | 348.4 | In-house | 3-268 (271) | alignment | |||
Range on Protein: 23-289
Range on HMM: 3-268/271.0
ESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQIT
.. ..|. ...||.| .|.|. |. .|||||||.|||..|.|.... .|..|...|.|||||||||..|.|.|.||..||..||....||||||||....
keevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssvn
QVYGFYGECMRKYgNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKD
..|||. |..||| . ... |.|.|..|..||..|. | |.||||||. |.|.|. |.|..| |.|| | |.|||||. . .|| |.||... .|.|
kiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFged
VTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYA
.. .||..|....|||||.....||.. .|.|| |..||||||....|.|....|...|. .....
avkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlk
|
|||||||||
PPP_1 | 23-277 | 2.1e-106 | 348.0 | In-house | 3-264 (264) | alignment | |||
Range on Protein: 23-277
Range on HMM: 3-264/264.0
ESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQIT
|....|. .|.|||| .|.|..|.....||.||.||||.|.|..||.||..|.|||||||||||||..|||.. ||..|||.||....||||||||||.|
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqvt
QVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDIL-------WSDPDPDREGFVESQRGA
.||||. |...|... ...|..|..||.|..||.||| |..|||||||. ..|||. ..|..|||.||.|.| | .||.. ..|.. .|.|||
kvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRGa
GYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEV
|| .||||| .|||.|... |||||.....||..|...|. |..||.||.....|....|..
gylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvkl
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 18-286 | 1.2e-101 | 332.7 | In-house | 7-274 (282) | alignment | ||
Range on Protein: 18-286
Range on HMM: 7-274/282.0
CEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHE
| |..|.....|..|.|.|.. . |.. ||..|||.|||..|.| .|...| |..|||||||||||| .|.||| || ..|..||... |||||||
evklkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhe
SRQITQVYGFYGECMRKYGNPtVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGY
| .|...|||| || |.|.. .|| ||..|..| .||..|| |.||||||||. |..||. . | |||..| | |.|||||| ...|. |..|| .
sasinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsf
SYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFN
..|||| .|||.|... |.||||. |||. ...| ||.||||||.. .|......|.|.| |.
tfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfq
|
|||||||||
0053225 | Metallo-dependent phosphatases | 5-292 | 5.3e-101 | 330.8 | In-house | 6-292 (293) | alignment | ||
Range on Protein: 5-292
Range on HMM: 6-292/293.0
TFNLDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLR
...|| .|| | .. .|.|...... ...||.|..|.|..|.. ...|.||.||...| |..... | .|.....||||.||||..|.|.. || .|||.
lllldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalkll
YPSRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDpD
||....|||||||.......|||..|..||||. .|..... ...| .||.|.. |..|||||||. ..|||. ..|....|.||.| |.|||||| .
ypdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpd.l
REGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAP
..|.. |.||.|. .| ...||||..|....|||.||...|||...||.|| ||.|||||..|.||........|.| . | ..|. .
wsgwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 11-289 | 1.2e-89 | 293.3 | In-house | 14-292 (298) | alignment | ||
Range on Protein: 11-289
Range on HMM: 14-292/298.0
CIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRIT
.... . .... |. .... .. |... . . . |. .|..| ||.|||. |.| .|. .| ||.|||||||||||| ...|.| || . |..||...
slsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnff
LLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVE
||||||| .| .||||| || |.| . .... | ..|. | ..|.| . |.|.|||||. |.||.. | | .. ..| |.||.||. .|. |
llrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwae
SQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYA
..||... .|.|| .|.. .. ..||||. |||. . ..|| |..|||.||.. | |....|.|||. |. .
nsrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlk
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 10-292 | 5.2e-83 | 271.7 | In-house | 23-310 (322) | alignment | ||
Range on Protein: 10-292
Range on HMM: 23-310/322.0
HCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSP----VTVVGDVHGQFYDVLEIFKIGGQC-PDTNYLFLGDYVDRGYHSVETISLLTCLKLR
. .|...| . |.. . .| ..|||| ... . ||. . .|| ||.||||||.|.||.. |. .. ||| ||.|||| .|||.| .| ..||
ellelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkll
YPSRITLLRGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGL-SPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDP
|| .. | |||||| .. ..||| ||. || . .| . |||.|..| .| .|.| . ||||| | ...|... .||... |.||.| ..|||||..
yPnhfflsrGnhesdnmnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqe
dREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEV-NEKLERYFNTYAAAP
..| .|.|| | .| ||| .||..|....|||.|.. ..||. | || ||.||||||.. ||....... ...|. |.|. | .
.anGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 8-279 | 2.6e-82 | 270.0 | In-house | 28-311 (452) | alignment | ||
Range on Protein: 8-279
Range on HMM: 28-311/452.0
LDHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPS
|. |.. | | |... .| .. .|| .|... |. .|.||.||.||||||.|..|..||. .|.||||||||||||.|.|.. | .||. |||
levlkehflkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiayps
RITLLRGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDRE-
.. |||||||.| .|. . | || ||.. .|.. ..| || | .||.... .|||||||| |.|.|| ||||.|.|. |.| |.||||| | .
tlfllrGnhecrhlteyftfkeeckikyse.evydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledyge
-----GFV-ESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDN------KLSTVWSAPNYCNRCGNMASIVEVNE
|| .| || | |. . .|||.|.. |||||. .||. .. | |..|||||.. | |.......
ekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyen
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 23-287 | 4.4e-81 | 265.2 | In-house | 10-273 (281) | alignment | ||
Range on Protein: 23-287
Range on HMM: 10-273/281.0
ESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQIT
. |... ... .. .|... || .|..||||.|.|| |. ..|.. |. |.. ..||||||||| .|.|.. || .||.||. || ||||||| ..
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasvn
QVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKD
..|||| ||. ||| .| | . |. | ..| |.. . |.|||||| ..|... . . .. | . |.||.|||.. |.. .| ||... .||.
kiygfyvecvtkyGe.elwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGkn
VTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNT
| .. ... ||||||...|||..| || ||.|.||||. | |... |.|.|. . .
vvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislva
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 19-287 | 3e-80 | 262.7 | In-house | 6-279 (284) | alignment | ||
Range on Protein: 19-287
Range on HMM: 6-279/284.0
EILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQC------PDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLL
..| | . |. . .||. |. .||..||..|||.|||| |.| .... | ...||||||||||| .|.| |.|| ..||..| ...||
kllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfll
RGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQ
||||||| . . |||| || ..| . .... | | . ..|.... | |.|||.| |...|.. |.| ..|. | ..|. |.||. . ||. ||.
rgnhesrpvnmqygfyleckkryse.alyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesp
RGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNT
|||| ..|.. .||.. |.. ..||||. ||||. . |.|| |..||| || . |.|....|.|.|. |..
rgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftv
|
|||||||||
PPP_2 | 50-242 | 1.9e-79 | 259.0 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 50-242
Range on HMM: 1-197/198.0
VTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEMFD
|||.||.|||..|.|..|| |...|...|||||||||||..|.|.. ||..|||.||....||||||||.....||||. |...|.|. .|.|...|.|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
YLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDIL----WSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQL
.|..||.||| ...||||||.. ..|||| .|..|.|.||.| | | .|||. ..|.. .|.||||. .|.||| ..|..||.. |||||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 22-295 | 1e-77 | 254.3 | In-house | 25-298 (299) | alignment | ||
Range on Protein: 22-295
Range on HMM: 25-298/299.0
PESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQI
| .... . |. ..|.. . |. .|. |.||.|||. |.| ||.. | ||.|.|||||||||| .|.|.|| | |..|| |. .|||||| |
keqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpai
TQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGK
.||||| || ..| .| | . |... .. .| | |.|||||| ..||.. | | |. || |.||.||| .. || | .|.
nrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyvfgq
DVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAPQSL
|| ... ... . ||||. |||. . ..|| |..||| || . | |.|..|.|.| | . .|.||
dvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpksl
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 14-286 | 1.7e-77 | 253.2 | In-house | 3-277 (287) | alignment | ||
Range on Protein: 14-286
Range on HMM: 3-277/287.0
KLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLR
| . . .. | |. .|..|.| . . |...|.|.|||.|||. |.| ||. |. |...||||||||||| .|.| . || .||..|| .. |||
kygvldafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllr
GNHESRQITQVYGFYGECMRKYGnPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQ--EVPNEGALSDILWSDPDPDREGFV-E
|||| ..| ..|||. | .||.. ..| | ..|..|.. |.... | |.|||.|| |.|..| | . . .|| |.||.||. | ..| .
GnhevkkinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfeln
SQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFN
.|. .|| . .|.. ... |.|||.. .||. |||..| ||.||| |. . |....| |.. || |
kiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfv
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 16-285 | 8.8e-77 | 251.5 | In-house | 20-288 (300) | alignment | ||
Range on Protein: 16-285
Range on HMM: 20-288/300.0
QKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGN
| | .| | .| | .||.... .. |. .| .|||||||. |.| .| | | .|||||||||||| .|.||| || | |..|| . |||||
tknvclknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgn
HESRQITQVYGFYGECMRKyGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGA
|| ..|.||||| || |. | .|| | . |. | .|||. |.|||||||| |.|.|. . | .||. | . |.||||| . . . .||
hecanvtrvygfydeckrr.cnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergv
GYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYF
| | | .||.. .. . ||| . |||. . | | ||.|||||| | ... |.| | |
sycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsf
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 17-287 | 8.8e-77 | 251.0 | In-house | 4-271 (280) | alignment | ||
Range on Protein: 17-287
Range on HMM: 4-271/280.0
KCeiLPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNH
.| . | |... .| |..| .. . |. .||.|.||.|||. |.| .|. . ||.|||||||||||| . .| | || . |.||| .. .|||||
ac..ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnh
ESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAG
| .| . |||. |..|.| . ... | |..| | ..|.. |.|.|||||. |.|... | | . ..| |.||.||. . |. |..||.
evisinrkygfkdevkrrysl.alynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvs
YSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNT
. .|..| . . ... |.| ||. |||. . |.|| ||.|||.|.. | |... |.|.|. |.
vifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfev
|
|||||||||
PPP_4 | 50-242 | 1.4e-75 | 246.7 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 50-242
Range on HMM: 1-196/197.0
VTVVGDVHGQFYDV-LEIFKIGGQCP-DTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKyGNPTVWKYFTEM
||||||.|||..|. |...|.||. . ...|.|||||||||..|.|.. ||..|||.||....||||||||......|||. |...| . ...|.....
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVP-NEGALSDI-LWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQL
||.|..||.||| ...||||||.. |.|.|. ..|..|.| .|... |. ||||| .. ||. .|.||||. .|.||| .||..|... |||.|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 76-288 | 1.8e-74 | 243.7 | In-house | 101-312 (317) | alignment | ||
Range on Protein: 76-288
Range on HMM: 101-312/317.0
TNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSI
.||||||||||| .|.| ..||..|||.|| ...||||||||| . . |||| |. ..| . .... | .| | ..|.... | |.|||.| . |..
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa.alyeafqlafnvlplcavvnkkilcmhGGiseelldl
DQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIV
.|...|.| ..|. | |.|. |.|||.. .|. ||.|||| ..|.. .||.. ... ..||||. .|||. . | || |..|||.|| . |.|...
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl
EVNEKLERYFNTY
.|..||. .|..
svdkklkisinvl
|
|||||||||
PPP_5_Dcr2 | 50-242 | 4.3e-74 | 241.8 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 50-242
Range on HMM: 1-198/199.0
VTVVGDVHGQFYDV-LEIFKIGGQCP-DTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNPTVWKYFTEM
|||.||.|||..|. |..|| ||. . ...|.|||||||||..|.|.. ||..|||.||....|||||||..|....|||. |...||.. ..|.....
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVP-NEGALSDI-LWSDPDPDREG-FVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQL
||.|..||.||| ...|||||||. ||.... ..|..|.| ..| .|. ||||| .. || ...|.||||. .|.||| .||..|... |||.|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 16-286 | 3.9e-73 | 239.3 | In-house | 18-290 (297) | alignment | ||
Range on Protein: 16-286
Range on HMM: 18-290/297.0
QKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGN
.... | . .. | ... .. .. |. .|. |.||.|||| |.| .|. || | .|||||||||||| |.||| || . |...|. . |||||
llskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgn
HESRQITQVYGFYGECMRKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSP---SALSIDQIKVLDRFQEVpNEGALSDILWSDPDPDREGFVESQ
|| . .||||| || ..| .. | ..|..| .. .| . | |.|||||| ...| .. ..| .| .|. ..|.||.|| ||.| |
hecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenq
RGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFN
|||| .|.| |. . |.. . ||||. |||. . || |..||| || . | |... ..|||. |.
rgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfe
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 18-289 | 2e-70 | 230.4 | In-house | 3-273 (280) | alignment | ||
Range on Protein: 18-289
Range on HMM: 3-273/280.0
CEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHE
|... | | .. ... |||. | .|. |.||.| |. |. .| . |. |. . .||||||||| . .| . || |||.|| || |||||||
cnvmtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhe
SRQITQVYGFYGECMRKYGNPtVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGY
. . ..|||| || ||| .| | |. . ....| . . |.|||||| . .| |. . | | . | | |.||||| ||.. | || |
tpsvnkiygfyvecqykygvg.lwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisy
SYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYA
.|| | . .. ... ||||||. |||. . .| ||.| |||| . | |..| .| .|. |.
mfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfqqli
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 12-286 | 1.9e-69 | 226.8 | In-house | 7-284 (290) | alignment | ||
Range on Protein: 12-286
Range on HMM: 7-284/290.0
IEKLQKCEILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITL
..| . . .. | || .|..|.| . |. .|...|||.|||. ..|. |. |. |. ..|||||||||| .|.| || |.|.||. .. |
llkygvldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhl
LRGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRF--QEVPNEGALSDILWSDPDPDREGF-
|||||| |.. ..|||. | .|| |. .|| . ..|. ||. | ... | |.|||.|. | . .| | . . .|| |.||.||. |.
lrgnhevrkvnrlygfkeelarkrgs.rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddti
-VESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFN
.. ||. .||.. .|.. .. |.|||.. .|.. |||.|| ||.||| |. . |. .|..| | || .
alnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsiv
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 40-282 | 9.1e-66 | 215.2 | In-house | 22-265 (284) | alignment | ||
Range on Protein: 40-282
Range on HMM: 22-265/284.0
ESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNPT
. . |. ||. ..||.|||| |.| .| | .|||||||||||| | .||| || . |. .| .. .|||||| | ..|||| || |.| .|.
qpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecslinkiygfyeecqrrynkps
VWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALS-DILWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIR
|.. | .| . ..|.. . | |.|||.| . |.. . | . |. .|. ||||||| ..|. || | .| | ..|. ... ..|
vyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldrlqidlvvr
AHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLE
|||. |||. . . .| |..||| || . | |... ||..|
ahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlv
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 32-283 | 6.2e-64 | 209.1 | In-house | 31-284 (307) | alignment | ||
Range on Protein: 32-283
Range on HMM: 31-284/307.0
KMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGEC
. . .. || . .| |. ||||.|||| |....| . |. |.| |.| ||||||| |.|.| || . |. || | ||||||| .. . |||| ||
eaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeec
MRK---YGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKDVTLRFL
. |. .| | |. | ..|.| | |.||||||. .|... . | | . |.||.|||| . | ||.|...| .|
vtsipkcge.eiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgtnviddvc
QNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLER
. .. ||||||.|.||| | || |..||| ||| | .. |.| |
krlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgi
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 77-289 | 5e-61 | 199.7 | In-house | 121-332 (339) | alignment | ||
Range on Protein: 77-289
Range on HMM: 121-332/339.0
NYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNpTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSID
||||||||||| |.| . |||.||| || || ||||||||| . |||| | .| ... | .||. . ..|.|...| |.|||.| |..
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsfn
QIKVLDRFQEVPNEGALSDILWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVE
|. |. | |.|. | |.|. |.|||| .|. | ||| . .| ||.. .| .|| ||. |||. . .| |..|||||| . | |...
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
VNEKLERYFNTYA
...||. | .
idkklkisinvfr
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 28-281 | 5.6e-58 | 189.5 | In-house | 4-280 (290) | alignment | ||
Range on Protein: 28-281
Range on HMM: 4-280/290.0
EITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVL----EIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQ
. |. . |..| .. |..||. |.||.||.. |. ....| . ...|||||||||| .||| |. | ||. |||.. ||||||| . ...
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqe
VYGFYGECMRKYGNP--TVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQI----KVLDRFQEvPNEGA--LSDILWSDPDPDR----------
. ..||.. |.|. ||. |...||.| .||.||. ..|||.|. .. . .| ..|.|... . .|| |||||||. ||
sieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkd.didgaplaldilwsdpaedrdlslrgelvl
-EGFVE-SQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKL
||||. ..|| |. ...| .||..| .....|||. |.. . .| ||.|. .|| . | |. ..||
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGssneaalilvdkkkl
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 44-285 | 7.6e-55 | 179.4 | In-house | 3-250 (263) | alignment | ||
Range on Protein: 44-285
Range on HMM: 3-250/263.0
QEIRSPVTVVGDVHGQFYDVLEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLRGNHESRQITQVYGFYGECMRKYGNP----T
|...|. ..|| |||. |.| ||. | . |.||||||||||| ||.| | || ||| | .. ||||||| . | . |||. | ... .
lelqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyes
VWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDRFQEVPNEGAL-SDILWSDPDPDREGFVESQ-RGAGYSYGKDVTLRFLQNNKMQHII
|...| ..| |. ..||. . | |.|||.|| |.|.|. . | . | |.||.||. | .|| . | .|| . . .. |.
vynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidliv
RAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYF
||||. || . | .| ||.|| | | |..| ||. || |
rahqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsf
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 25-278 | 6.6e-52 | 169.6 | In-house | 10-287 (302) | alignment | ||
Range on Protein: 25-278
Range on HMM: 10-287/302.0
TIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIG-----------GQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLR
. . ... ||| |... || .|||.|||.|||| |.. |.. ..|||||||||..|.| |.|. .||. ||.. |||
ellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillr
GNHESRQITQVYGFYGECMRKYGNPT---VWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDR-FQEVPNEGALSDILWSDPD-------
||||.. | ||| .| ..|. .|. | |.| .. .||.. | | |||||.|| |...|| ..| ..|| .. |.|..||
gnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaa
-PDREGFV-ESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVN
... .. . || ... . . .. .. |.|||| |.. |.|| |..|||.| | | ....|.
vsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvd
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 25-278 | 9.1e-52 | 169.1 | In-house | 11-288 (302) | alignment | ||
Range on Protein: 25-278
Range on HMM: 11-288/302.0
TIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIG-----------GQCPDTNYLFLGDYVDRGYHSVETISLLTCLKLRYPSRITLLR
. . ... ||| |... || .|||.|||.|||| |.. |.. ..|||||||||..|.| |.|. .||. ||.. |||
ellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyillr
GNHESRQITQVYGFYGECMRKYGNPT---VWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIKVLDR-FQEVPNEGALSDILWSDPD-------
||||.. | ||| .| ..|. .|. | |.| .. .||.. | | |||||.|| |...|| ..| ..|| .. |.|..||
gnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvqllaa
-PDREGFV-ESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVN
... .. . || ... . . .. ... |.|||| |.. |.|| |..|||.| | | ....|.
vsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvd
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 49-241 | 2.4e-43 | 141.7 | Pfam-A | 2-197 (200) | alignment | ||
Range on Protein: 49-241
Range on HMM: 2-197/200.0
PVTVVGDVHGQFYDV----LEIFKIGGQCPDTNYLFLGDYVDRGYHSVETISLL--TCLKLRYPSRITLLRGNHESRQITQVYGFYGECM----------
...|.||.||...| |...||..... ...|||||.|||| .| ||. || .|||..| .. ||||||||......|||. |.
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
-----------------------RKYGNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSALSIDQIkvldrfqevpnegalsdilwsdpdpdregfv
...... .. .. | |..|. .|..| | ..||.||.| | |.|
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
esqrgAGYSYGKDVTLRFLQNNKMQHIIRAHQ
... .|.|.. .|.........|.|.
.....gselfgpdalekllekygvdlvlrGHt
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 9-183 | 2e-34 | 112.0 | In-house | 21-201 (383) | alignment | ||
Range on Protein: 9-183
Range on HMM: 21-201/383.0
DHCIEKLQKCEILPESTIKEITDKMKELLISESNVQEIR----SPVTVVGDVHGQFYDVLEIF-KIGGQCPDTNYLFLGDYVDRGYHSVETISLLTCLKL
.. ||.... ..| . .| . |. | . |.... ||| ||.||.. |.| |. | | .. .|.| ||.|||| .||| . .| .| |
eklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillalll
RYPSRITLLRGNHESRQITQVYGFYGECMRKY--GNPTVWKYFTEMFDYLSVAAIIDEAIYCVHGGLSPSAlSIDQIKVLDR
|| . | ||||| . ||| | . || . . . . ..| .| .|..||| |. ||||.| .. ... .. ..|
vypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdkt.dlelldkier
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 194-292 | 3.6e-21 | 68.3 | In-house | 238-336 (383) | alignment | ||
Range on Protein: 194-292
Range on HMM: 238-336/383.0
SDILWSDPDPDREGFVESQRGAGYSYGKDVTLRFLQNNKMQHIIRAHQLCMDGYQTLFDNKLSTVWSAPNYCNRCGNMASIVEVNEKLERYFNTYAAAP
||||||| .. . .. ||.| .| ||| ..||. ... .||.|. ..||. |.|. |..|| || . | . | ....|. .. | |.
ldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqask
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 19-71 | 1.4e-09 | 30.6 | In-house | 7-59 (317) | alignment | ||
Range on Protein: 19-71
Range on HMM: 7-59/317.0
EILPESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGG
... |. . |. . .||. .| |...|||.|||.|||| |.| .... |
dlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
|
|||||||||
subfamily_YNL217W_pd | Subfamily YNL217W | 50-122 | 1.7e-08 | 27.3 | In-house | 12-80 (235) | alignment | ||
Range on Protein: 50-122
Range on HMM: 12-80/235.0
VTVVGDVHGQFYDVLEIFK--IGGQCPDTNYLFLGDYVDRGYHSVETISLLtclklrYPSRITLLRGNHESRQIT
. ||||||| . ...|... |||. .. ...|| ...| .|||..|.. . ..|||| .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvll
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 23-71 | 4.6e-07 | 22.2 | In-house | 13-61 (339) | alignment | ||
Range on Protein: 23-71
Range on HMM: 13-61/339.0
ESTIKEITDKMKELLISESNVQEIRSPVTVVGDVHGQFYDVLEIFKIGG
. . |. . .||. || . .. .|. |.||.|||| |.| .. . |
aaelaelchrareliwsepiflkleapicvmgdihgqfddllamldmng
|