Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPP3C_pd | Subfamily PPP3C | 64-518 | 2e-235 | 774.7 | In-house | 1-452 (452) | alignment | ||
Range on Protein: 64-518
Range on HMM: 1-452/452.0
RVVPSVKYPKSLPLPHDVLFNEDKTINLPKLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNY
||| .|..||| | .. .|.|.....| |.|||..||||.......|...||..|.||.||..|||||||.|| |||||||.|.|| .||.||.|.|
rvvkkvplpkskklteeevfdetgkpklevlkehflkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfe..vgGdPastky
LFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIA
|||||||||||||.|...||||.||.||.|.|||||||||||||||||||||| .|||||||| ..|||..||||||.|..|||.||||||.||.||||
lflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecrhlteyftfkeeckikyseevydacmesfdslPlaallnqqflcvhGGlspeikslddik
NIDRFKEPPSSGPMCDLLWSDPMEEFSPEI-REHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDATGFPSVITLFSAPNYLD
..|||||||.|||.||||||||.|... | .|.||||.||||||.|||.|||.|||||.|||.|||||||.|||.|. ...||||||.|||||||||||
kldrfkeppasGplcdllWsdPledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyld
AYNNKGAVLRYENNVMNIRQFTCSPHPYWLPNFMDVFTWSMPFVSEKVAEMLLVLLNLCNDEEAEKNENAQtVKDTSEEEKRRQMLRAKVKSVSKMMRMF
.||||.|||.|||||||||||..|||||||||||||||||.|||.|||.|||. .||.|.|.|.||.|... |..||.|||....|.|.....|..|.|
vynnkaavlkyennvmnirqfnssphpywlpnfmdvftwslpfvgekvtemlvnilnicsddelekeeeee.skeesesekrkevirnkiraigklarvf
SLLRQERETIMMIKSFSpSRKIPQGLLTEGKDALKKALGDFAQARKMDLINEKRPP
|.||.|.|.....|... ....|.|.|.|||..|...| .|..|.|.|||||| ||
svlreesesvlllkglt.tgalprgalsegkegleeklssfeeakkldlineklpp
|
|||||||||
0045823 | Metallo-dependent phosphatases | 63-520 | 8.4e-148 | 485.7 | In-house | 2-452 (473) | alignment | ||
Range on Protein: 63-520
Range on HMM: 2-452/473.0
DRVVPSVKYPKSLPLPHDVLFNEDKTINLPKLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEnDIGGNPAnTN
|||...| .| . .| ...|| . ..| .| ||.. ||.|. .|.......|.||| |||.|......|.|.|| |||..||....| .|| .|. ..
drvlklvlipvlrlltlpllfillglldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrlle.kigfppe.dr
YLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDI
..||||.||||..| ||. .|.| ||.||. .||||||||.|.|. .. |..|.|.||.|..|. . | ...|||||. .||.|..|||||||...||.|
lvflGDlvDrGpdslevlelllalkikypgnvfllrGNHElrllnglygfgdetlekygedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqi
ANIDRFKEPPSSGPMCDLLWSDPMEEFSP-EIREHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDATGFPSVITLFSAPNYL
..|.|. |.|..|...|||||||.|.. .|..| .|..||..||....||. ||.||.| ..|.|... ||... . ..|....||.||||||.
reierpleipddgllldllwsdPweddgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYc
DAYNNKGAVLRYENNVMNIRQFTCSPHPYWLPNFMDVFTWSMPFVSEKVAEMLLVLLNLCNDEEAEKNENAQtvkDTSEEEKRRQMLRAKVKSVSKMMRM
. ..|..|||..........|| .||||..||.|.|||..|.||..||..|.||.|||...|.| ...|. .. |.....|| |.. ..|..|.
grggnlaAvlvidedlisfiqfdpsphplilplfldvfllslpfllekltellllllnivsddellededil...glllleallellrnkilalgkllrv
FSLLRQERETIMMIKSFSPSRKIPQGLLTEGKDALkkaLGDFAQARKMDLINEKRPPIL
||.||.|.|.....|...||. .|.|||..||..| |.....|.|.||||||.|| |
fsvlreesesvlllkgltpsgllplgllllgkell...lesleealkldlineklppsl
|
|||||||||
PP2Ac_SM00156 | 105-378 | 8.4e-101 | 329.5 | In-house | 2-261 (271) | alignment | |||
Range on Protein: 105-378
Range on HMM: 2-261/271.0
NHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFenDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECR
.. .|.|... ..|||..|..|..|.||.||.||.|||..||.... . .| |....|.|||||||||..|.|||..|.| || ||....|||||||..
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrll..elageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEss
HLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPmeefsPEIREHFVPNDvRG
.......|.||. .||..|.|. ..| |..||||||.. |.||.||||||....||||....|.||.| .|...||||||| . ..| |. ||
svnkiygfeeevkrkygkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdp.....eqkekgfqpsk.rg
CSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
.|.... .||. ||.||.| .|||||... ||.. .. ...|.||||||.|...||.|||..|.|..
lsvvFgedavkeflkknnlkliiRahevvdeGyeffadk......klvtifsapnycdefsnkaavlkveknlk
|
|||||||||
PPP_1 | 106-370 | 1.3e-100 | 329.0 | In-house | 3-261 (264) | alignment | |||
Range on Protein: 106-370
Range on HMM: 3-261/264.0
HDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRH
.. ..|..|...|.|.||..|..|...||||||.||||.||.|.|.. ||....|||||||||||||..|.|....|.| |..||...||||||||.|.
eeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkv..ggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrq
LTEYFTFKEECL-HKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFS-PEIREHFVPNDVR
.|....||.|.| .|||.|.|. .|..|. ||||||...|.|..||||||....||.| ...|..| |..|..||||..| ...| .. .|..|.| .|
vtkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiR
GCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAV
|..||........|||||.| ..|||||....||... .. .|.|.|||.|| .. .|.||.
GagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkr......kvvtifsasnyyeegsnrgay
|
|||||||||
PPP_3 | 104-378 | 3.6e-98 | 320.9 | In-house | 2-263 (271) | alignment | |||
Range on Protein: 104-378
Range on HMM: 2-263/271.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFenDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
|..... |.||...||||||..|....||.|||||.|||..||...| ..||....|.|||||||||||..|.||...|.|.||.||....|||||||.
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelf..knggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEs
RHLTEYFTFKEECL-HKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEfspeirEHFVPNDV
|.......||.|.| .|....||. ..| |..||||||...|.|..||||||.||.||.| ...|..| |..|...|||.|...|. |... |..
rqinkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpek......eeglensk
RGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQndatgfPSVITLFSAPNYLDAYNNKGAVLRYENNVM
||...|.. .....||.|||| .|||||....||... . .|.|.||||||.....|.||.|. |.. .
rGagllFgpdvteefleknkLkliiRaHelkeeGyeilhd......gkvvtvfSapnycerasnagailkleealt
|
|||||||||
0049330 | Metallo-dependent phosphatases | 91-392 | 3e-94 | 308.6 | In-house | 17-305 (309) | alignment | ||
Range on Protein: 91-392
Range on HMM: 17-305/309.0
LPKLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEnDIGGNPAnTNYLFLGDYVDRGYFSMEVIIYLYACKINY
| .| |... ...|. ....... .| ||| .||.|......|.|.|| |||..||....| .|| .|. ....||||.||||..| ||. .|.|.|. |
ldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrlle.kigfppe.drlvflGDlvdrGpdslevlllllalklly
PNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEefs
|. .||||||||.|.|. .. |..|.|.||..|... ... ...|||||. .||.||.|||||||...||.|....|. |.| |..||||||||..
pdnvfllrGNHElrllnglygfgdetlrkygaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplp...
peIREHFVPNDvRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDatgfpsVITLFSAPNYLDAYNNKGAVLRYENN-VMNIRQFTCSPHP
|||.|.||. ||..... . ||..||.||.| .||.|.|. ||... ... .||.||||||.. ..|.||||..... |.....| ..|..
..iregfapnp.rglgvvfghtaverflkkngldliirghgavfgGyltffdgk......litvfsapnycgrlgnlgavleidedlvisfllfepvpll
YWL
..|
lll
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 103-378 | 6.6e-89 | 290.8 | In-house | 9-270 (282) | alignment | ||
Range on Protein: 103-378
Range on HMM: 9-270/282.0
RLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHE
.|.. .. ...|.| ||| ..|.|...|||....|| |||..||...|| ..| |...|||||||||||| .|.|.|. | | ||.||...||||||||
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfe..tsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhe
CRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEfspeiREHFVPNDv
. ...... |..|| ..|| ... .|. || ||||||.. | ||.||||||..| |..| .| | | |..| .|||||||| .| .. . ||
sasinriyGfydeckrrysiklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdke.....vlgwsend.
RGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
|| |. .. ..| .|||||.| ..|||. ..||... .. ..|.||||||.. ..|.||||. .....
rGvsftfgkdvvekflqkndldlivrahqvvedGyeffakr......qlvtvfsapnycgefdnagavlsvdeell
|
|||||||||
0053225 | Metallo-dependent phosphatases | 89-380 | 2.6e-87 | 285.9 | In-house | 7-285 (293) | alignment | ||
Range on Protein: 89-380
Range on HMM: 7-285/293.0
INLPKLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFeNDIGGNPAnTNYLFLGDYVDRGYFSMEVIIYLYACKI
..| .| |... .|. ....... .| ||| |||.|......|.|.|| ||...||.... ..|| .|. ....||||.||||..|.||. .|.|.|.
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlall.ekigfppe.drlvflGDlvdrGpdslevlelllalkl
NYPNTFFLLRGNHECRHLTEYFTFKEECLHKY-SEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPme
||. ..|||||||...|. .. |..|.|.|| ..|..| ... ...|||||| .||.|..|||||||. .||.|..|.|. ..| |...|||||||
lypdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdp..
efspEIREHFVPNdVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQndatgfPSVITLFSAPNYLDAYNNKGAVLRYENN-VMNI
......|. ||..... . ||. ||.||.| .||.|... ||... . ....|.|||||||. ..|.|||| .... |...
....dlwsgwlps.yrglgvvfghtavlrflkkngldliirghqvvpdgylpwfd......gklvtvfsapnylgrlgnlgavlaldeglvwgf
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 93-391 | 2.9e-83 | 272.5 | In-house | 23-314 (322) | alignment | ||
Range on Protein: 93-391
Range on HMM: 23-314/322.0
KLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAP----ITVCGDTHGQFYDLIKIFEndIGGNPAN-TNYLFLGDYVDRGYFSMEVIIYLYACK
.| |.| .. .|.. ...|...| |.|.|.|.|.... . .|||||.|||||||. ||| . | |.. ||| ||.|||| ||.|||. |.. |
ellelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnife..lnGlpseenpylfnGdfvdrGsfsveviltllgfk
INYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGL-SPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPM
. ||| ||| ||||| .. . . |..|. .||.|.|.|. ||.|| |||| ..| |.| .|||| | | ||||. .|||...||..| ...||||||
llyPnhfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpq
EEFSpeirehfVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRY--ENNVMNIRQFT
|. . . || . . ||..|.| .||.|| .. ||... . ..||.|||||| | .||||... ... .....|.
eanG.......rspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdG......klitvfsapnycdqmgnkgafitlrgddlklkfktfe
CSPHPYW
.||
avehpdv
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 96-387 | 8.5e-82 | 267.6 | In-house | 9-287 (290) | alignment | ||
Range on Protein: 96-387
Range on HMM: 9-287/290.0
EHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFF
|.. .|. ..| |....| |||.|| . .|..|.||||| ||||.||...| |||. .||||||||||||||.|.| . .| | |. |..
eklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfk..iggkspdtnylflgdyvdrgyysvetvtllvalkvrykerit
LLRGNHECRHLTEYFTFKEECLHKYSE-EVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEefspeiR
.|||||| | .|. . | .||| ||.. .|. ..|. |. |||.||.... .|.|||||| |.|||.| ..||..| | ||.|||||||| . |
ilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpdd......r
EHFVpNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDatgfpsVITLFSAPNYLDAYNNKGAVLRYENNVM-NIRQFTCSP
. .. ||. | . .| ..|.| ..|||. ||.. ... |.|.|||||| |..|.| .... .. || .|
ggwg.isprgagytfgkdisekfnktngltliarahqlvmegynwshdrn......vvtifsapnycyrcgnqaailelddklkysflqfdpap
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 105-378 | 1.6e-81 | 266.7 | In-house | 17-276 (288) | alignment | ||
Range on Protein: 105-378
Range on HMM: 17-276/288.0
NHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECR
. ..| .. . | ||| .| . .|..|.||||| |||||||...|. .||. .||||||||.||||..|.| .. | | |. ||. |.|||||.|
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfk..vggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesr
HLTEYFTFKEECLHKY-SEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSPEIrehfvpnDVR
..|. . | .|||.|| | .|. . || |. |.|||...|| .|.||||||.|.|||.| ||| .| | .||.|||||||| . . . |
qitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwav.......spr
GCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
| ||. ..| .| ..|.. ..|||. |||.|... .|.|..||||| |. |.|......
gagylfgsdvveqfneandielicrahqlvmegyklhfne......kvltvwsapnycyrcgnvaaileldeeld
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 104-378 | 1.4e-78 | 257.0 | In-house | 24-285 (298) | alignment | ||
Range on Protein: 104-378
Range on HMM: 24-285/298.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
....|| .....| .|..| ..|..|.|||.|||| |||. ||...|.. .| | ..|||||||||||| ...|||. | | |..||| ||||||||||
ikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdk..agfppdanylflGdyvdrGrqnlevivlllaykvkypnnffllrGnhec
RHLTEYFTFKEECLHKY-SEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSpeireHFVPNdV
.. . . |.||| ..| | ..| . ||||||.||. |. ||.|||||. .|.||..... | ...... ||||.|| . . . .|
eainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavk.....gwaen.s
RGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
|| |. . .| .|.| .. |.||| . ||.. .. ..|.||||.|.. ..| ||.. .....
rGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaek......klvtifsaphycgqfdnsaavmkvdeklv
|
|||||||||
PPP_4 | 133-333 | 1.3e-74 | 243.5 | In-house | 1-197 (197) | alignment | |||
Range on Protein: 133-333
Range on HMM: 1-197/197.0
ITVCGDTHGQFYDLIKIFENdIGGNPA-NTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITES
.||.||.|||..||. .. . .||.|. ...|.|||||||||..|.||...|.|.|..||....|||||||...|.....||.|.|.|...|... ....
vtvvGDiHGqlddlllkllk.ngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlekhgkeilkklqdv
FNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPP-SSGPMCDL-LWSDPMeefspEIREHfVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRA
|. ||||||...|.|..|||||.....||.| .|.|..| | ... ..|| |||||. | |. . | |||...|........||.||.| ..||.
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpr.....eaqeg.lansvrGagllFgpdvtekfleknnlkliirs
HEAQ
||..
helk
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 108-374 | 7.7e-74 | 241.6 | In-house | 18-283 (300) | alignment | ||
Range on Protein: 108-374
Range on HMM: 18-283/300.0
DVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLT
| |... |.| || .|....|.|| || ||||||...||. |||. .|||||||||||||..|.| |. | . |. || ||||||| | .|
tvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifk..iggqvpdtnylflgdyvdrglysvetisllivlklrypsritllrgnhesrqit
EYFTFKEECLHKY--SEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSPEI-----RE-HFVp
. . | |||.|| |....|| |. | |||... . |.||||||.....|.| .|||.| | | ..||||||| |. .| . |||
qvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennnptldhpdregqhfv.
NDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDatgfpsVITLFSAPNYLDAYNNKGAVLRYE
. ||. | | | ||..|.. .||||. | ||.....| . |..||||| || ..| .
vsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnk......lstvwsapnycyrcgnkasilely
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 104-377 | 2.9e-73 | 239.5 | In-house | 15-274 (290) | alignment | ||
Range on Protein: 104-377
Range on HMM: 15-274/290.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
|. .|. ..... ...| .| .. |..|.||||| ||||||| ..| . ||. .|.|.||||.|||||.|.| . .| . |..||. |||||||.
lpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrt..ggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhes
RHLTEYFTFKEECLHKYSE-EVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPmEEfspeIREHFVpnDV
|..|. . | .|||.|| . ... ..|. |. |..||..... ||.|||||||.||||.| |.| .| | |..|||.|||| |. . . |
rqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdp.ed....vetwav..sp
RGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNDatgfpsVITLFSAPNYLDAYNNKGAVLRYENNV
|| ||. . . .|.. |.| ..|||. . |.| .... ..|..||||| | ..|. |..
rgagylfgskvtkefvhinnlklicrahqlveeglkymfdek......lvtvwsapnycyrcgnvasilaledae
|
|||||||||
PPP_2 | 133-332 | 1.5e-72 | 236.5 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 133-332
Range on HMM: 1-197/198.0
ITVCGDTHGQFYDLIKIFenDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECL-HKYSEEVYDFITES
.|||||.|||..||...| . |.......|||||||||||..|.||...|.|.|..||....|||||||.........||.|.| .|....||. ..|
vtvcGDlHGqldDLlilf..knglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqev
FNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLwsdPME-EFSPEIREHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAH
|..||||||...|.|..|||||..||.||.| ...|..| |..|...||| ..| .|. .|... |..||...|.. ......|.|||| .||||
felLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldll...eeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaH
EA
|.
ev
|
|||||||||
PPP_5_Dcr2 | 133-332 | 7.8e-72 | 234.4 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 133-332
Range on HMM: 1-198/199.0
ITVCGDTHGQFYDLIKIFENDIgGNPA-NTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHK-YSEEVYDFITE
.|||||.|||..||. |..... |.|. ...|.|||||||||..|.||...|.|.|..||....|||||||...|.|...|..|.|.| .....|. ...
vtvcGDlHGqlddlllilfkeg.gdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsd
SFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPP-SSGPMCDL-LWSDPMeefsPEIREHFVPnDVRGCSYLYSYRAVCSFLQKNKLLSVIR
.|. ||||||...|.|..||||||.||.......|.|..| | ..| ..|| |||||. .. . ... .||...|....... ||.||.| .||
vfdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdpr....daqegckln.seRGagllfgpdvtekfleknnlkliir
AHEA
.||.
shel
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 105-376 | 1.7e-71 | 233.6 | In-house | 7-264 (280) | alignment | ||
Range on Protein: 105-376
Range on HMM: 7-264/280.0
NHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENDigGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECR
.. |. .... .|| . |...|.||..|||| |||. ||...|.. . | ..|||||||||||| . .|||. | | |. |||.|..||||||.
keadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarv..sfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevi
HLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSPeirehfVPNDVRG
.. . . ||.|. ..||...|. . | .. |||.||..|. ||.|||||.....|||.|.. | ... . ||||.|| .. . .. ||
sinrkygfkdevkrryslalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtg......waensrg
CSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENN
.|... | . .| .. ..| |. . ||.. .. ..|.||||.||. ..|. |||. ...
vsvifganvvkdltekldidliarghqvvqdgyeffadk......klvtvfsapkylgefdnsaavlivder
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 104-381 | 1.9e-71 | 233.3 | In-house | 10-275 (287) | alignment | ||
Range on Protein: 104-381
Range on HMM: 10-275/287.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
.. .|..|... . |||| |.|..||||||..||.|||. ||..||.. |......||||||||||| |.||...|.. || ||. |||||||.
fsdkdilevlekieeileplpalleveapitivGdihGqlddllrifna..vGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhev
RHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSS--GPMCDLLWSDPMEEfspeiREHFVPND
... . . |||| .|..|..| . |. ||| | .. . ||.|||.||..|.||.. . . . | . | . ||||.|| .. . | .|
kkinklyGfkeelkrkrqerlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd.....aktfelnk
VRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYEnNVMNIR
.|. | .. . | ..|.| .. ..|||| .. ||.. ... ..|.|||| | | |||. . ......
iraisvvfGkkevddllkkldidlivrahevseeGyaflfdk......rlvtvfsapyysgedtnlgavvvvs.kslels
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 104-378 | 6.2e-67 | 218.9 | In-house | 24-285 (299) | alignment | ||
Range on Protein: 104-378
Range on HMM: 24-285/299.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFenDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
.. .........| ... ....|..||||| |||| |||. ||..|| |. | | ..|.|||||||||| .|.|. |.. ||.||. ||.|||||||
vkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrif..dkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhec
RHLTEYFTFKEECLHKY-SEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFspeirEHFVPNdV
. . | ||| ..| | .. . ..|.|.||. |.... ||.|||||| ..||| . .. | ..||. ||||.|| . . .| |
painrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsv.....kdwlan.v
RGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
|| ||.. | ... .. | |||. . ||.. .. ..|.|||| | ..| |... ..|..
rgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffask......klvtifsaphycgqfdnsaaimkvdenlv
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 104-375 | 1.7e-65 | 214.5 | In-house | 25-282 (300) | alignment | ||
Range on Protein: 104-375
Range on HMM: 25-282/300.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
|. .....|.. | |.. .|.|... .. . || |||. ||...| . | | .|||||||||||| |.| |. |.. ||.||. ||||||||||
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftk..cgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhec
RHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEefSPEIREhfvpNDVR
.| . | .|| .. ... . ..||.|||||.. || .|.|||||| ....|.| . | . | | . ||||||| . |.. | .. |
anvtrvygfydeckrrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptd..ssnewe....dner
GCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHlqNDAtgfpSVITLFSAPNYLDAYNNKGAVLRYEN
| || | |. ||.| . | ||| . ||.. || |..|.|||||| ..| |||. .
gvsycynkvainkflnkfgfdlvcrahmvvedgyeff..ndr....slvtvfsapnycgefdnwgavmsvse
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 104-378 | 4.5e-64 | 209.6 | In-house | 8-274 (284) | alignment | ||
Range on Protein: 104-378
Range on HMM: 8-274/284.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNP------ANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLL
|.. ..||. | |.. ||. ...|||....|| |||| ||. ... . | | ...||||||||||| ||.||| |.| |. .|. |||
lkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalld..lngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfll
RGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFSpeirehF
||||| | . . | .|| ..||| .|. . .|||.||.|... | .|.|||.| |. |... ...| . | | ..|| |.|| .| .
rgnhesrpvnmqygfyleckkrysealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaeve......g
VPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNVM
. ||. .. .|| ||.| || |.|||. ||.. .. ..|.|||| | ..| .|||. .....
ykesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadr......klvtifsapsycgqldniaavlnvdeelv
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 106-379 | 6.7e-64 | 208.8 | In-house | 10-270 (281) | alignment | ||
Range on Protein: 106-379
Range on HMM: 10-270/281.0
HDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFenDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRH
........... |. .| .|.....||.| || |.|| ||...| .. | .... ..||||||||| |.||.| |.. || |.. .||||||| .
keeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlf..ellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheias
LTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMeefsPEIREHFvpNDVRGC
. . | .|| || ||.. . . || ||..||.. . ||.||||||.. .||.. |. . ... | . ||||.|| .. | . . .||
vnkiygfyvecvtkyGeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpd....nkveewk..assrGs
SYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNV-MN
|... | .. .. .|||| .||.. .||.||.||| . |.| .|||. .... ..
sftfGknvvddvckrleveliirahqvvqdGyevlsgr......klitvfsvpnycafyknaaavlkvdetlgis
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 104-375 | 2.9e-62 | 203.3 | In-house | 16-277 (290) | alignment | ||
Range on Protein: 104-375
Range on HMM: 16-277/290.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFeNDIgGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHEC
.. .|..||.. . |||| |.|..|||||.. || |||. .|.. | ... | | . ..|||||||||| |.|| ..|. || |... |||||||.
fsdkdileilekieeileplpalleveapivivgdihgqldallryf.dav.gyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhev
RHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPP--SSGPMCDLLWSDPMEEfspeIREHFVPND
|.. . |||| | . ... . |. |.| | .. | ||.|||.|..|.. . . . . . | | . ||||.|| .. . . |
rkvnrlygfkeelarkrgsrlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrd....kddtialnk
VRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYEN
|. | .. ... ..|.| | ..|||| .. |... ... ..|.|||| | | ||... .
qraisvvfgkkglddllkklalslivrahevkeegfnflfdk......klvtvfsapyysgndtnlgaiatvse
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 106-377 | 1.5e-59 | 194.7 | In-house | 5-264 (284) | alignment | ||
Range on Protein: 106-377
Range on HMM: 5-264/284.0
HDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENDigGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRH
.|| .. | .|..|.| ||.|..|| .||| |||| ||...|... | | .|||||||||||| .| |. |.| |. .|| ||.|||||||
pedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkn..gfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecsl
LTEYFTFKEECLHKYSE-EVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDR-FKEPPSSGPMCDLLWSDPMEefspeIREHFVPNDvR
. . . | ||| ..| . || . | .||.||. . ||.|||.| .. . .. | | | .| |.||||| . ... . || |
inkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptn.....fqkgwnpns.r
GCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNV
| ||.. |. .|.. .. |.|||. . ||.. . ..|.|||| | ..| ||. ..|.
gvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanr......rlvtifsapfycgqfdnaaavmyvnknl
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 104-377 | 1.8e-59 | 194.4 | In-house | 6-290 (302) | alignment | ||
Range on Protein: 104-377
Range on HMM: 6-290/302.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENDIGGNPA---------NTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTF
... ... .... | |.|| ||... .|.|. || |||| ||..|. . . . | . ..|||||||||. |.| | ..| |. ||. .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
FLLRGNHECRHLTEYFTFKEECLHKYSE----EVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSS-GPMCDLLWSDPMEE-
|||||||.. . ..|.|| .... |... | | .|||||. | ||.|||.|| ...|.|| .|.| . . |||..||..
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
--FSPEIREHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNV
... . ... | ||| |... || . .. | ..||| .|.|.. .. ..|.||||.|.. .||||||. . |
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadk......klltifsaprymnesdnkGavlkvdtng
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 104-377 | 2.6e-59 | 193.9 | In-house | 7-291 (302) | alignment | ||
Range on Protein: 104-377
Range on HMM: 7-291/302.0
LNHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENDIGGNPA---------NTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTF
... ... .... | |.|| ||... .|.|. || |||| ||..|. . . . | . ..|||||||||. |.| | ..| |. ||. .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
FLLRGNHECRHLTEYFTFKEECLHKYSE----EVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSS-GPMCDLLWSDPMEE-
|||||||.. . ..|.|| .... |... | | .|||||. | ||.|||.|| ...|.|| .|.| . .. |||..||..
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
--FSPEIREHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENNV
... . ... | ||| |... || . .. .| ..||| .|.|.. .. ..|.||||.|.. .||||||. . |
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadk......klltifsaprymnesdnkGavlkvdtng
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 106-374 | 1.4e-58 | 191.6 | In-house | 25-282 (297) | alignment | ||
Range on Protein: 106-374
Range on HMM: 25-282/297.0
HDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRH
. |.... .| ...... ....|.||| |||| |||| ||...| || | .|||||||||||| ||.| |. | | |...| .|||||||||
eervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhr..ggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhecef
LTEYFTFKEECLHKY-SEEVYDFITESFNALPLAALMNGKFLCIHGGLSP---DIKTLDDIANIDRFKEPpSSGPMCDLLWSDPMEEFSPeirehFVPND
. . . | ||| ..| | .| . . || |||. |. | ||.|||||| . ||| . .|.| .| . ..||||.||. .| |. |.
vnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsg.....fmenq
vRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYE
||. . || . || | |||. . ||.. ..|.|||| | ..| |.. .
.rgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagr......klvtifsaphycgqfdncaafmscd
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 111-378 | 3.7e-58 | 190.1 | In-house | 4-280 (290) | alignment | ||
Range on Protein: 111-378
Range on HMM: 4-280/290.0
EIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIkIFEND---IGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLT
. ..| .|| .| |.....|. | || ||.. ||| .||. .| . . ...|||||||||| ||.|.| ||.| |. || ..||||||| . ..
slcdvavdilaaeerllelksptyvlgdlhgnyrdli.yfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq
EYFTFKEECLHKYS---EEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANI----DRFKEPPSSGPMC-DLLWSDPMEEFSPEIR-----
| ...| |. .|. |||.. ... |.|||||| .. | .|.|.|. |.| |. | .|.|.. |. |.||||| |. .|
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl
-EHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKmhLQNDAtgfpSVITLFSAPNYLDAYNNKGAVLrYENNVM
| ||.|| || ....| |. .||..| | |.||||....|.. ||... ..|.||. .| . |. .| ... .
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGir..lqqkg....rlltvfsssrycGssneaalil.vdkkkl
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 160-377 | 5.3e-55 | 179.8 | In-house | 100-305 (317) | alignment | ||
Range on Protein: 160-377
Range on HMM: 100-305/317.0
NTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTL
. .||||||||||| ||.||.| |.| |. ||. |||||||| | . . | .|. ..||...|. ||.|||.|..| | ||.|||.| .. |
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldl
DDIANIDRFKEPPSSGPMCDLLWSDPMEEfspeirEHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPN
. . ...| . | | ..|| |.|| .| .. . || . .. .|| ||.| .| |.|||. . ||.. . ..|.||||.
kqldklkrpldipdvGvladltwadpdae......vkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadr......klvtifsaps
YLDAYNNKGAVLRYENNV
| .| .|||. ....
ycGqldniaavlsvdkkl
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 107-387 | 1.2e-54 | 178.6 | In-house | 9-276 (280) | alignment | ||
Range on Protein: 107-387
Range on HMM: 9-276/280.0
DDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEnDIGGNPaNTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHL
..| |..| |. .| |.. |||| | || | |. |. ..|. || | . . .||||||||| .||.| |.. || | . .||||||| .
heiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfd.ligrvp.eeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsv
TEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPMEEFspeirEHFVpNDVRGCS
. . | || .|| .. . || .|...|.. . ||.||||||.. || | || | || | . ||||||| .. | .. .|| |
nkiygfyvecqykygvglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkg.....egwf.hsirgis
YLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHlqndaTGFpSVITLFSAPNYLDAYNNKGAVLRYENNV-MNIRQFTCSP
|.. | . .. .||||. . ||.| .| .||.|| ||| . | ||. . |. ....|. |
ymfgkgvveqacksleidliirahqvvqdgyemm.....agr.rlitvfsvpnycaqftnaaavvclnanlqvsfqqlippp
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subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 126-372 | 5.3e-50 | 163.5 | In-house | 2-241 (263) | alignment | ||
Range on Protein: 126-372
Range on HMM: 2-241/263.0
LIQVEAPITVCGDTHGQFYDLIKIFENdiGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYS-EEV
|....||| .|||||||. ||..||. | ..|.||||||||||| .|.|||. |.. |. | ..||||||| . . . . |. | ... |||
llelqapinicgdthgqyndllrifna..cgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreev
YDFITE----SFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPM-CDLLWSDPMEEfspeiREHFVPNDVRGCSYLYSYRAVCSFLQ
|. . . |. .||.|... . ||.|||.|| .|.|||| | | . |. |||||.|| .. . | || .| | .. . | . .
yesvynhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekd.....akgfepnkiraisnvfgkkevddlck
KNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLR
. . ..|||. . || . . .||.||| | | ||.
rldidlivrahqvveygyaffadr......rlitvfsasryqielcnyaavvv
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subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 109-376 | 9.2e-50 | 162.5 | In-house | 25-281 (307) | alignment | ||
Range on Protein: 109-376
Range on HMM: 25-281/307.0
VIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFEndIGGNPANTNYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTE
. ... | |. | .|.... | | || |||| |||..| . | | .| |.| ||||||| .|.|.|. |.. || ||. ||||||| .. .
fenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfi..llgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnk
YFTFKEECL---HKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIANIDRFKEPPSSGPMCDLLWSDPmeefSPEIREHFvpNDVRGC
..| |||. | ||.. .. || ||..||. | ||.|||||| . ||.. | . | | . |.||.|| | . | ||
kygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadp....dpsvfewk..assrgs
SYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHlqndaTGfPSVITLFSAPNYLDAYNNKGAVLRYENN
. . . .. . .||||. || . .| .||.|||| | . |.| |.||. ..
gftfgtnviddvckrlgveliirahqmcfdgywvl.....sg.rklitifsapmycnfyknagcvlkvdet
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subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 162-375 | 4.2e-44 | 144.0 | In-house | 121-322 (339) | alignment | ||
Range on Protein: 162-375
Range on HMM: 121-322/339.0
NYLFLGDYVDRGYFSMEVIIYLYACKINYPNTFFLLRGNHECRHLTEYFTFKEECLHKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDD
||||||||||| |||||.| | | |. ||. .||||||| | . . | | ..| ..|. . . || .|..|..| .|.|||.| . ....
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyrydaqlyecfqnmfnvfpfcavinntimcmhggisehltsfnq
IANIDRFKEPPSSGPMCDLLWSDPmeefSPeIREHFVPnDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHlqnDATgfpSVITLFSAPNYL
.. . | | | | . || |.|| | . . | ||.|... |. .||.| | ||| |. . ||.. | ..|.||||||
fsvfkrpleipdvgvltdltwadp....dp.tekgykp.sargasfvfgppalraflkkldlqmvirghqvvedgyeff...dgr...rlvtifsapnyc
DAYNNKGAVLRYEN
.| ||. ..
gqndntaavfsidk
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Metallophos | Calcineurin-like phosphoesterase | 132-333 | 5.4e-43 | 140.6 | Pfam-A | 2-199 (200) | alignment | ||
Range on Protein: 132-333
Range on HMM: 2-199/200.0
PITVCGDTHGQFYDL--IKIFENDIGGNPANTNYLFLGDYVDRGYFSMEVIIYL--YACKINYPNTFFLLRGNHECRHLTEYFTFKEECL----------
.|.|.||.||...|| . ..|.... ....|||||.|||| | |.. .| .. |...|. .||||||||........ |..|.|
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
------------------------HKYSEEVYDFITESFNALPLAALMNGKFLCIHGGLSPDIKTLDDIanidrfkeppssgpmcdllwsdpmeefspei
... ...... | |.||||.|| .||.|..||.||.. .. |||
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
rehfvpndvrgCSYLYSYRAVCSFLQKNKLLSVIRAHEAQ
.|.|....|.. .|.|... |.|.|. .
...........gselfgpdalekllekygvdlvlrGHtHk
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subfamily_PPP7C_pd | Subfamily PPP7C | 93-269 | 1.2e-35 | 116.0 | In-house | 22-203 (383) | alignment | ||
Range on Protein: 93-269
Range on HMM: 22-203/383.0
KLQEHFFAEGRLNHDDVIEIVKMAAEILEKEPTLIQVEA----PITVCGDTHGQFYDLIKIFENDigGNP-ANTNYLFLGDYVDRGYFSMEVIIYLYACK
|| |.| . .| |..|.. |...|.. | . .|.. .||||| ||.. ||. |. . | | .. .|.| ||.|||| |.|... |.|
klieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilykn..GlpseenpyvfnGdfvdrGkesveillillall
INYPNTFFLLRGNHECRHLTEYFTFKEECLHKY---SEEVYDFITESFNALPLAALMNGKFLCIHGGLSpDIKTLDDIANIDRFK
. ||. ..| ||||| | . | | .|| .... .. . | ||||.|.. | | .|||.| |. |. . .|.| |
lvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis.dktdlelldkiersk
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subfamily_PPP7C_pd | Subfamily PPP7C | 277-378 | 1.1e-13 | 43.7 | In-house | 237-326 (383) | alignment | ||
Range on Protein: 277-378
Range on HMM: 237-326/383.0
MCDLLWSDPMEEfspeirEHFVPNDVRGCSYLYSYRAVCSFLQKNKLLSVIRAHEAQNAGYKMHLQNdatgfpSVITLFSAPNYLDAYNNKGAVLRYENN
. |.|||||... | .|| .|| . ..||| .| .||.|| . ||.. .. |.|.||| || . |.|| .. ..
vldilwsdpkak......eGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdk......kvltifsasnyyeeGsnrGayvklgkd
VM
..
lt
|
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subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 105-151 | 1.5e-10 | 33.8 | In-house | 10-56 (317) | alignment | ||
Range on Protein: 105-151
Range on HMM: 10-56/317.0
NHDDVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFE
.. ..||. | |.. ||| ...|||.|..|| |||| ||. ...
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalld
|
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subfamily_YNL217W_pd | Subfamily YNL217W | 133-217 | 1.1e-08 | 27.9 | In-house | 12-90 (235) | alignment | ||
Range on Protein: 133-217
Range on HMM: 12-90/235.0
ITVCGDTHGQFYDLIKIFENDIGGNPANTNYLFLGDYVDRGYFSMEVIIYLyackinYPNTFFLLRGNHECRHLTEYFTFKEECL
. | || || . .||..... ||| | ...|| ...| |.||. |. . ..|||| | .| |.. .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllaykwvkkpkg
|
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subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 108-151 | 6.4e-08 | 25.0 | In-house | 15-58 (339) | alignment | ||
Range on Protein: 108-151
Range on HMM: 15-58/339.0
DVIEIVKMAAEILEKEPTLIQVEAPITVCGDTHGQFYDLIKIFE
.. |... | |.. || ....|||| | || |||| ||. ...
elaelchrareliwsepiflkleapicvmgdihgqfddllamld
|
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Med3 | Mediator complex subunit 3 fungal | 509-610 | 7.1e-07 | 15.0 | Pfam-A | 247-348 (379) | alignment | ||
Range on Protein: 509-610
Range on HMM: 247-348/379.0
MDLINEKRPP--ILDRVNSRGELLRMNSRGElfrINSKGDLFRSNSYAdLKPPQGPQETI--KITECHEQnITTNNINPNSITTNE-NNSNEQLQQQQQQ
|.|.|.. | . .| . ..|. |. | |.. |. .. ..... . ..| ... . ||| | .| . |. ... ||||.|
mqllnqvaPnnamasPlNnmspmrnlnqmGn...qnnggqmnnsannG.nmnnmskennlnanmtpsksm.lnlnniTPaniLsmslnldfdlqqqqqpq
QQQQQPP
|.|.|.
qaqsqnq
|