Gene DDB_G0289835 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP1
Subfamily DdisHP1-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP083_AA protein Get Run
DdisP083_AA_20-228 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Dicty-HP1-1_pd Subfamily Dicty-HP1-1 22-229 2.9e-127 412.6 In-house 1-210 (210) alignment 
Range on Protein: 22-229
Range on HMM: 1-210/210.0
KKVYFIRHGQSTFNIAYlaNNKVDPYLFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFLKENSnIKCLVSPLHSETVITSDD
||||.||||.||||.||  |.|||||||||||||||.||||||||||||.||||||.|||||||||.||.....|.|||.| ||||||.||.|..|||||
kkvyiirhgestfnkay..nekvdpylfdarlteegkkqanelsenvekllqdvelvisspltraldttkiallkllkeks.ikclvsslhrellitsdd

NGRPRSIIEKENPDFNFGDLQERWWYLPS-----SIKDDLSIDTELYFKTNGYKEPIESILHRIEEFKKFLLSRNESTIAVVGHSDFFYHFFDRSIPHMK
|||..||||||.|.|.|..||||.||||.     ..|||||||||||||..||||.|||.|.|.|||||||||||||.||||||.||||.|.||||.|.|
ngrvksiiekeypefdfsllqerrwylpeleelielkddlsidtelyfkkigykesiesllkrveefkkfllsrnessiavvghadffyyftdrsilhlk

NCQIVSWCSETNE
|||.|....|..|
ncqvvklnlelse
0051064 Phosphoglycerate mutase-like 21-220 8.3e-26 83.8 In-house 3-213 (241) alignment 
Range on Protein: 21-220
Range on HMM: 3-213/241.0
KKKVYFIRHGQSTFNIAYLANNkvdpYlFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkE-NsNIKCLVSPLHSETvITS
 |..|..|||.|..| . .  .    . .|. |||.|..|| .| |   ... ......||||.||. | .  .. .      ...  | |   |     
mkrlyLvRHGesewnaegrlqg....w.tDvpLtelGreqaralgerladlgikfdavysSpllRaiqTaeiiaeal..glp.llpvvvdprlrEi.dfg

DDNGRPRSIIEKENPDFNFGDLQERWWYLPSS--IKDDLSIDTELYFKTN-----GYKEPIESILHRIEEFKKFLLSR---NESTIAVVGHSDFFYHFFD
.. |.... |... |.. .  |.. ....|    . |.|.. ..|....       . |... . .|.... . ||.|   ......||.|. .  ... 
alegltleeiaekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgknvlvVsHggviralla

RSIP---------HMKNCQI
. .          ...|...
yllglpleellrlnlpngsv
0048955 Phosphoglycerate mutase-like 22-208 8.8e-26 83.7 In-house 1-189 (240) alignment 
Range on Protein: 22-208
Range on HMM: 1-189/240.0
KKVYFIRHGQSTFNIAYLANNkvdpYlFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkE-NSnIKCLVSPLHSETvITSD
...|..|||.|..| . .  .    . .|. |||.|..|| .| |   ..  ...|..||||.||. | .  .. .    .  ..  | |   |     .
prlyLvRHGesewnaegrlqg....w.tDvpLtelGreqaralgerLadlgikfdlvysSpllRaiqTaeiiaeal..glpl.lpvvvdprlrEr.dfga

DNGRPRSIIEKENPDFNFGDLQERWWYLPSSI--KDDLSIDTELYFKTN-----GYKEPIESILHRIEEFKKFLLSR---NESTIAVVGHSDFFYHFF
. |.... |... |.. .  |.. ....|  .   |.|.. ..|....       . |... .  |.... . ||.|   ......||.|. .  ...
legltldeiaekfpeelvlwlrdpldvrppllelldellllldlryalldedllpggEsladvaaRvlaaleellaralkpgknvlvVsHggvirall
0036777 Phosphoglycerate mutase-like 22-228 9.4e-24 76.8 In-house 3-220 (247) alignment 
Range on Protein: 22-228
Range on HMM: 3-220/247.0
KKVYFIRHGQSTFNIaylaNNKVDPYlFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkENSNIKCLVSPLHSEtVITSDD
|..|..|||....|.    ....    .|. |||.|..|| .| | . ..   .....||||.||. | .  .. .  ..|...  |.|   | .   . 
krlyLvRHGetewna....egrfqgw.lDvpLtelGreqakalgellkelglpfdavysSpllRAiqTaeiileal..glsllpvvvdprLrE.rdyGal

NGRPRSIIEKENPDFNFGDLQERWWYLP-------SSIKDDLSIDTELYFKTNGYKEPIESILHRIEEFKKFLLSR---NESTIAVVGHSDFFYHFFDRS
.|.... |... |.. .  ..  ..| |         . .|| ... |....  . |... ...|.... . || |   ......||.|. .   .. . 
egltkaeiaekypeelvawwrdpydyrppllelllelllldllryallpldllpggEsladvvaRvlpaleellarllkdgenvlvVsHggvlrallayl

IP---------HMKNCQIVSWCSETN
           ...|. |. .  . .
lglsledilrlnlpngsitvlelddd
0049178 Phosphoglycerate mutase-like 21-220 2.4e-21 68.9 In-house 3-211 (243) alignment 
Range on Protein: 21-220
Range on HMM: 3-211/243.0
KKKVYFIRHGQSTFNIAYLANNkvdpyLFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkENSNIKCLVSPLHSETVITSD
....|..|||....| . .  .      .|. |||.|..|| .| |   ..  ......||||.||. | .  .. .    ....  |.|   |    . 
mtrlyLvRHGetewnaegrlqg.....wtDspLtelGreqAralgellaelglkfdavysSplkRaiqTaeiileal..glpllpvvvdprLrErdfGal

DnGRPRSIIEKENPDFNFGDLQERWWYLP-SSIKDDLSIDTELYFKTN----GYKEPIESILHRIEEFKKFLLSR---NESTIAVVGHSDFFYHFFDRSI
. |.... |... |.  .  ..  ... |   . .|| ...  ..  .       |. . .. |.... . || .   ...|..||.|. ..  .  .  
e.gltkaeiaakypeelvawwrdpydarppalllldlllplldrlladldllpggEsladvaaRvlpaleellaellhdgktvlvVaHggvirallalll

P---------HMKNCQI
          ...|. .
glpleellrlnlpngsv
0043909 Phosphoglycerate mutase-like 21-228 2.7e-21 68.6 In-house 2-224 (249) alignment 
Range on Protein: 21-228
Range on HMM: 2-224/249.0
KKKVYFIRHGQSTFNIAYLANNkvdpyLFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkENSNIKCLVSPLHSETVITSD
.|..|..|||....| . .  .      .|. |||.|..|| .| | . ..   .....||||.||. | .  .. .  ......  |.|   |    . 
mkrlyLvRHGetewnaegrfqg.....wlDspLtelGreqaralgealkelgipfdavysSplkRAiqTaeiileel..gldklpvevdprLrErdfGal

DnGRPRSIIEKEnpdfnFGDLQERWWY----------------LPSSIKDDLSIDTELYFKTNGYKEPIESILHRIEEFKKFLLSR---NESTIAVVGHS
. |.. . |...     ..... .|..                |.  ..| . .|..... .    |... ...|.... . || |   .......|.|.
e.gltkaeiaek.....ypeelvawlrrsydvlpplleeldelllellldyaladldplldrppggEsladvvaRvlpaleellarllkdggnvliVaHg

DF----FYHFFDRSIP-----HMKNCQIVSWCSETN
 .    .......|..     ...|. |. .  . .
gvlrallayllglsledilrlnlpngsitvlelddg
0036887 Phosphoglycerate mutase-like 22-221 3.5e-21 68.2 In-house 2-181 (202) alignment 
Range on Protein: 22-221
Range on HMM: 2-181/202.0
KKVYFIRHGQSTFNIAYLANNkvdpYlFDARLTEEGEKQANELSENVEkyLQDVELIISSPLTRALCTTRRGFGKFlkensNIKCLVSPLHSEtVITSDD
...|..|||....|.. .  .    . .|. |||.|..|| .| | .     .. ...||||.||. | .  .. .     .... | |   | .  .. 
trlyLvRHGetewnvegrlqg....d.ldvpLtelGreqaralgerla..glpfdavysSpllRaiqTaeiiaeal.....glpvivdprlrE.idfgal

NGRPRSIIEKENPDFNFGDLQERWWYLPSSIkddlsidtelyfktngykEPIESILHRIEEFKKFLLSR-NESTIAVVGHSDFFYH----FFDRSIPH--
.|.. . |... |.. .  |.  ... |.                    |... ...|.... . || | ......||.|. .       ....|. .  
egltleeiaekypeelaawlrdpydfrppgg..................EsladvvaRvlaaleellarldggnvlvVsHggvlrallayllglsledll

----MKNCQIV
    ..|. ..
rlrklpngsvt
0035570 Phosphoglycerate mutase-like 23-223 1.9e-20 65.7 In-house 1-173 (219) alignment 
Range on Protein: 23-223
Range on HMM: 1-173/219.0
KVYFIRHGQSTFNIAYLANNkvdpylfDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGfgkflkensNIKCLVSPLHSETVITSDdN
..|..|||....|.. .  .       |. |||.|..|| .| |   ..  .. ...||||.||. | .           ...  ..|   |    .  .
rlyLvRHGetewnlegrlqg.......dvpLterGreqaralgealadlgipfdavysSpllRaiqTaeii.........glpveidprLrEidfgdl.e

GRPRSIIEKENPDFNFGDLQERWWYLPssikddlsidtelyfktnGYKEPIESILHRIEEFKKFLlsRNESTIAVVGHSDFFYHFFDRS----IP-----
|.... |... |.  .  |.  ..| |                     |... . .|.... . |  .......||.|. .   .. .     .      
gltldeiaekypeelaawlrdpydyrp..................pggEsladvvaRvlpaleel..edgenvlvVsHggvirallayllglpleeilrl

HMKNCQIVSW
...|. .. .
nlpngsvtvl
0039931 Phosphoglycerate mutase-like 23-221 2.7e-20 65.2 In-house 1-171 (219) alignment 
Range on Protein: 23-221
Range on HMM: 1-171/219.0
KVYFIRHGQSTFNIAYLANNkvdpylfDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGfgkflkensNIKCLVSPLHSETVITSDdN
..|..|||....| . .          |. |||.|..|| .| |   ..  .. ...||||.||. | .           ...  . |   |    .  .
rlyLvRHGetewnvegrlqg.......dspLterGreqaralgerlkdlglpfdavysSpllRaiqTaeii.........glpveidprLrEidfgdl.e

GRPRSIIEKENPDFNFGDLQERWWYLPssikddlsidtelyfktnGYKEPIESILHRIEEFKKFLLSrnESTIAVVGHSDFFYHFFDRSIP---------
|.. . |... |.  .  |.  ..| |                     |... . .|.... . ||.  .....||.|. .   .. .            
gltleeiaekypeelaawlrdpydyrp..................pggEsladvvaRvlpaleella..genvlvVsHggvirallayllglsleeilrl

HMKNCQIV
...|. ..
nlpngsvt
0037864 Phosphoglycerate mutase-like 22-209 4.2e-20 64.5 In-house 8-172 (211) alignment 
Range on Protein: 22-209
Range on HMM: 8-172/211.0
KKVYFIRHGQSTFNIAYLANNkvdpyLFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGFGKFlkENSNIKCLVSPLHSEtVITSDD
...|..|||....|.. .  .      .|. |||.|..|| .| | . ..  ......||||.||. | .  .. .    ..... |.|   | .   . 
trlyLvRHGetewnaegrlqg.....wldvpLtelGreqaralgealadlglpfdavysSpllRaiqTaeiileal..glpllpvevdprlrE.rdfgal

NGRPRSIIEKENPDFNFGDLQERWWYLPSSIkddlsidtelyfktngykEPIESILHRIEEFKKFLLSR---NESTIAVVGHSDFFYHFFD
.|.. . |... |.  .  |.  ... |.                    |.......|.... . || |   ..... ||.|. .   .. 
egltleeiaekypeelvawlrdpydfrppgg..................EsladvvaRvlpaleellarllkdgenvlvVsHggvlralla
0053607 Phosphoglycerate mutase-like 22-220 2e-19 62.3 In-house 2-172 (191) alignment 
Range on Protein: 22-220
Range on HMM: 2-172/191.0
KKVYFIRHGQSTFNIAYLANNkvdpylfDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRGfgkflkensNIKCLVSPLHSETVItSDD
...|..|||....| . .          |. |||.|..||  | |   ..  .. ...||||.||. | .           ...  | |   |     | 
trlyLvRHGetewnaegrlqg.......dvpLtelGreqaralaellaelglkfdavysSpllRarqTaeii.........glpvevdprlrEidf.gdw

NGRPRSIIEKENPDFNFGDLQERWWYLPssikddlsidtelyfktnGYKEPIESILHRIEEFKKFLLSrnESTIAVVGHSDFFYHFFDRSIP--------
.|.... .... |.  .  |.  ..| |                     |... ...|.... . ||.  .....||.|. .   .  .           
egltleelaekypeelaawlrdpldyrp..................pggEsladvaaRvlpaleella..ggnvlvVaHggvirallayllglpleellr

-HMKNCQI
 ...|. .
lnlpngsv
His_Phos_1 Histidine phosphatase superfamily (branch 1) 23-203 3e-18 59.2 Pfam-A 1-154 (158) alignment 
Range on Protein: 23-203
Range on HMM: 1-154/158.0
KVYFIRHGQSTFNIAYLANNKVDpylfdARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRgFGKflkeNSNIKCLVSPLHSETVITSDDn
..|..|||.| .| .  .. . |     . |||.|..||.|| .  ..  . .. ...|||.||. |..  . .    . .|.   .|   |  . . . 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle....eldipiikeprLrerdfgewe.

GRPRSIIEKENPdfnfgDLQERWWYLPSSIKDDlsidtelyfktngYKEPIESILHRIEEFKKFLL--SRNESTIAVVGHSDF
|.|.. ...| |     . .|.|.  . ... .              .|  . .  |...| . |.   ... .. .|.|  .
glpkeevkeefp.....eeyekwkrdkkefrpp.............egesladvyeRvapfleelieakdkgenvlivsHggv
His_Phos_1 Histidine phosphatase superfamily (branch 1) 23-203 3e-18 59.2 In-house 1-154 (158) alignment 
Range on Protein: 23-203
Range on HMM: 1-154/158.0
KVYFIRHGQSTFNIAYLANNKVDpylfdARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTRRgFGKflkeNSNIKCLVSPLHSETVITSDDn
..|..|||.| .| .  .. . |     . |||.|..||.|| .  ..  . .. ...|||.||. |..  . .    . .|.   .|   |  . . . 
rlylvRHGesewnkegrlqgwsd.....vpLtekGreqarelgkkLkradlpidavytSplkRaiqTaei.lle....eldipiikeprLrerdfgewe.

GRPRSIIEKENPdfnfgDLQERWWYLPSSIKDDlsidtelyfktngYKEPIESILHRIEEFKKFLL--SRNESTIAVVGHSDF
|.|.. ...| |     . .|.|.  . ... .              .|  . .  |...| . |.   ... .. .|.|  .
glpkeevkeefp.....eeyekwkrdkkefrpp.............egesladvyeRvapfleelieakdkgenvlivsHggv
0050036 Phosphoglycerate mutase-like 23-207 1.1e-13 43.4 In-house 2-140 (171) alignment 
Range on Protein: 23-207
Range on HMM: 2-140/171.0
KVYFIRHGQSTFNIAYLANNKvdpylFDARLTEEGEKQANELSENVekylqDVELIISSPLTRALCTTRRGFgkflkensnikclvsplhsetvitsddn
..|..|||....|.. .  .       |  |||.|..||  | |       .. ...||||.||  | .  .                            
rlyLvRHGetewnlegrfqgw.....tdvpLtelgraqaralgell.....pfdavysSpllRArqTaelil............................

grPRSIIEKENPDFNFGDLQERWWYLPSSIKDDlsIDTELYFKTNGYKEPIESILHRIEEFKKFLLsrneSTIAVVGHSDFFYHF
  .. |....  ...||... . .        .  ... |.. .    |...  |.|. .. . ||    ....||.|. .   .
..lpvivdprLrErdfGawegltldeiaakype..wlldlldlappggEsladvlaRvlpaleell....gnvlvvaHggviral
subfamily_TIGAR_pd Subfamily TIGAR 24-91 3e-09 28.8 In-house 3-63 (222) alignment 
Range on Protein: 24-91
Range on HMM: 3-63/222.0
VYFIRHGQSTFNIAYLANNKvdpylFDARLTEEGEKQANELSENVEKylQDVELIISSPLTRALCTTR
.. .|||.. ||   .   .      |  |.|.|..||  ... ..   . ...|.||.| ||  |. 
livVrhGetefnkekilqgq.....tdtpLsekGveQakrvakrLsn..ekinyifsSdllRAkqTae
subfamily_PMU1_pd Subfamily PMU1 27-216 6.5e-09 25.8 In-house 20-218 (233) alignment 
Range on Protein: 27-216
Range on HMM: 20-218/233.0
IRHGQSTFNIA-YLANNKVDPYLFDARLTEEGEKQANELSENV----EKYLQDVELI-ISSPLTRALCTTRRGFGKFLKE------NSNIKCLVS-PLHS
...|  ...    |   .... . |..||  |. |. .   ||     | |  .| .  ||.| ||| |   .|   | |       ....  .   |  
lkyGmekldaywallsgdengeildskltslGkdqvrrtGsnvllpmakqlGmlehvffsstlrraletalesfeavlaetqelpagtkvstriieslre

ETVITSDDNGRPRSIIEKENPDFNFG-DLQERWWYLPssikdDLSIDTELYfKTNgYKEPIESILHRIEEFKKFLL---SRNESTIAVVGHSDFFYHFFd
..     |. . ||.| .| .|..       .| |.|     ||  | ||. ||. ..|.   . .|  .  . |.   | .|  .|.| || ..   . 
tlGshtcdkrvarsaivdeyqdlslesghtvhwqyvP.....dlPeddelw.ktd.hretkveldkrtlatlfelaadlsseekfvalvthssvllsll.

RSIPHMK
|.. |..
raldhlr
subfamily_PGAM_pd Subfamily PGAM 23-91 1.1e-08 26.6 In-house 2-65 (248) alignment 
Range on Protein: 23-91
Range on HMM: 2-65/248.0
KVYFIRHGQSTFNIaylaNNKVDPYlFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTR
|. ..|||.|..|     .||   . .||.|.|.|...|..... ...   ..... .| |.||  |..
klvllRhGeselnk....enkfcgw.vDakLsekGkeeAkkagkalkqanlefdivytSvlkRaqqTle
subfamily_PFKFB_pd Subfamily PFKFB 19-90 5.9e-08 24.4 In-house 4-68 (198) alignment 
Range on Protein: 19-90
Range on HMM: 4-68/198.0
ISKKKVYFIRHGQSTFNIAYLANNKVDpylfdarLTEEGEKQANELSENVE-KYLQDVeLIISSPLTRALCTT
......|. |||.|  |       . .       |||.|...|..|.. .. . |...  . .| | |.  |.
lkpreiylvRhGeseknkkgriggdse.......LterGveyakklakfikeenlkel.rvwtselkrtiqTa
subfamily_TFC7_pd Subfamily TFC7 23-91 9.4e-07 19.6 In-house 2-71 (255) alignment 
Range on Protein: 23-91
Range on HMM: 2-71/255.0
KVYFIRHGQSTFNIAYLANNKVD-PYLFDARLTEEGEKQANELSENVEKYLQDVELIISSPLTRALCTTR
..|  |||     .  .  ..       |. |.|.| .||.||.. ..|  .  |.|.|||| | | |..
tiyiarhGyrsnwlpkgpypdpltgidsdvPlserGveqakelaiylkkldlkpeaifssPlyrcletsk