Gene DDB_G0275631 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily PPM-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP096_AA protein Get Run
DdisP096_AA_337-595 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CG9801_pd Subfamily CG9801 343-574 2.2e-109 354.7 In-house 1-251 (252) alignment 
Range on Protein: 343-574
Range on HMM: 1-251/252.0
RAGDPIADRYTCAVYNNRLITCLADGCNWGQKPKEAAQNASTAFIDYVISK-NDDMTNVKEVGKILFNAFECAHKSIMLGKDEFWEAGTTTLLGGVLLEI
|.||||||..|..|..||||..||||||||..|.|||..||.|||||. .. ....|.|.||||.|..|.|.|||||. ||.|.|||||||||||||||.
reGdPiaDkftvvvrknrlilalaDGcnWGerpaeaarsasaafidylskalskeittvqevgksllaaleeahksivegkselweaGtttLlggvllel

NKGSDKW-------------------SPQWEFVCASVGDCKAYLLS--QGEVTDITEGNRSNL-DAKDCGGRLGPHLEQGKPDLRNLNIFCASVYDEDII
.|...|.                   |..|.|||||||||||.|.|  . ||||||.|||||| ||.|.||||||..||||||||||..|...|..||||
ekeaekpesssqlgksevglsasnassskwgfvcasvGDckaflysakkkevtditkgnrsnlsDarDagGrLGPyveqgkPdLrnLklfftlveeeDii

MIVSDGVHDNLDPKHLGKTPNDMskefNLNGEKWTDVDFSKALVAKNAFTASLLE
..|||||||||||..|||||.|.    |||.|||.|....|||.||..||..|||
llvsDGvhDnlDPqtlgktprdl....nlnaekwsdleqdkaleaktkftkelle
subfamily_tipA_pd Subfamily tipA 445-596 7.2e-81 261.2 In-house 146-296 (296) alignment 
Range on Protein: 445-596
Range on HMM: 146-296/296.0
SDKWSPQWEFVCASVGDCKAYLLSQG--EVTDITEGNRSNL-DAKDCGGRLGPHLEQGKPDLRNLNIFCASVYDEDIIMIVSDGVHDNLDPKHLGKTPND
..|.|..|.|||||||||||.|||..  ||||||.|||||. ||||.||||||..||||||||||..|......||||..||||||||||||.|||||.|
inkssskWgfvcasvGdckafllskkskevtditkgnrsnvddakdpGGrlGPyveqGkPdlrnlklffllceeediillvsdGvhdnldPktlgktprd

MskefNLNGEKWTDVDFSKALVAKNAFTASLLETLAADSTDPNEISNRILEHCWN
.    .||.|||.||.|.|||.||...||.||..|.|||.|..|||....|||..
l....qlnyekwsdvefdkaleaktkytaellkkleadsidakeiseklvehcve
subfamily_tipA_pd Subfamily tipA 339-444 2.6e-56 180.6 In-house 1-106 (296) alignment 
Range on Protein: 339-444
Range on HMM: 1-106/296.0
NTTERAGDPIADRYTCAVYNNRLITCLADGCNWGQKPKEAAQNASTAFIDYVISKNDDMTNVKEVGKILFNAFECAHKSIMLGKDEFWEAGTTTLLGGVL
|||.|.|||||||.|..||.||||..||||||||..|.|||.|||.||.|....|......||..||.|..|||.|||.|. ||...|||||||||||||
nttkregdpiadrftvqvyknrlivaladGcnWGkrPaeaatnasaafvdflseksseintvkdaGkfllsafeaahkkiveGksdiweaGtttllGGvl

LEINKG
||... 
leleqs
subfamily_CG9081_pd Subfamily CG9081 344-533 6.6e-36 114.3 In-house 1-191 (195) alignment 
Range on Protein: 344-533
Range on HMM: 1-191/195.0
AGDPIADRYTCAVYNNRLITCLADGCNWGQKPKEAAQNASTAFIDYV---ISKNDDMTNVKEVGKILFNAFECAHKSIMLGkdefwEAGTTTLLGGVLLE
||.|.|| ..  . .|  | .|||| |||.|.. ||. | .. ..|.   . | .  .| ... | |....| |.|||.       .. .|||  .|. |
agePvadvfavvarennaimaladGvnWGkkarlaarsavagavaylndklfklsakpnsrdlfklllesleeaqksilen.....sgtlttlsiavvce

InKGSDKWSPQWEFVCASVGDCKAYLLS--QGEVTDITEGNRSN---LDAKDCGGRLGPHLEQgKPDLRNLNIFCASVYDEDIIMIVSDGVHDNLDPK
. |...| | || .. .||||  ... |  ...|...| .  |.    |... || |||   . .||| || .  ..|.. ||....|||| ||.||.
l.kankkissqWglfvvsvGdspvfvyspdnksvrevtvashskdgirdvrlsGGalGpaiGt.dpdlenlslsylpvaeGdivfltsdGvsdnfdPv
subfamily_Sponge-PPM-1_pd Subfamily Sponge-PPM-1 345-534 3.3e-33 104.9 In-house 2-193 (199) alignment 
Range on Protein: 345-534
Range on HMM: 2-193/199.0
GDPIADRYTCAVYNNRLITCLADGCNWGQKPKEAAQNASTAFIDYVISK----NDDMTNVKEVGKILFNAFECAHKSIMLgkdefWEAGTTTLLGGVLLE
|.|.|| ..  . .|  | ..||| |||.||. ||. | .. | |.  .    .   || ... | |..... |||||.       |  .|||  .|. |
GepvadvfavvarennaimaiadGvnwGkkprlaarcavqgaiayisdnlfklsakptnsrtltklllesldeahksile.....heGtlttlsiavvce

INKGsDKWSPQWEFVCASVGDCKAYLLS--QGEVTDITEG---NRSNLDAKDCGGRLGPHLEQgKPDLRNLNIFCASVYDEDIIMIVSDGVHDNLDPKH
.    .. | .| .. |||||   .. |  ...|...|     .  . .|.. || ||| . . .||| || .    |.. ||.....||..||..|. 
lkpn.srsssrwglfvasvGdspvfvyspdtksvheatvachdkdGirtarlsGGalGpaiGt.dpdlenlslsylpvaeGdivllttdGisdnfapvv
0049733 PP2C-like 350-538 3.8e-15 49.1 In-house 20-200 (235) alignment 
Range on Protein: 350-538
Range on HMM: 20-200/235.0
DRYTCavynNRLITCLADGCNWGQKPKEAAQNASTAFIDYVISknddmTNVKEVGKILFNAFECAHKSIMLGKDEF--WEAGTTTLLGGVLLeinkGSdk
|.. .    ..|. ..||| . ..  . |.... ....... .     ..  .. ..| .||. |.. ..    .   .  . ||..  .|     |.  
Davlv....glllfavaDGhgghaagevasellvetllellle.....lllldleealrkaflaaneallelalaspelagmgtTavvalld....gg..

wspqwEFVCASVGDCKAYLLSQGEVTDITEGNRSNLDAKDCGGR-----------------LGPHLEQgkpdlrnLNIFCASVYDEDIIMIVSDGVHDNL
      ...|.|||. ||||..|... .|| .. . .  . . .                 || .| .         ...  . ..|.... |||..|.|
.....klyvanvGDsrayllrdgklvqltedhspvnelerqriitaggavrvpgrlaltralGdlllk.......pdvtvlelepgdflllasDGlwdvl

DPKHLGKT
... . ..
sdeeivdl
0034914 PP2C-like 346-595 1.8e-12 40.0 In-house 33-275 (295) alignment 
Range on Protein: 346-595
Range on HMM: 33-275/295.0
DPIADRYTCAV-----YNNRLITCLADGCNWGQKPKEAAQNASTAFIDYVIS-KNDDMTNVKEVGKILFNAFECAHKSIMLGKDE---FWEAGTTTLLGG
..  |.... .      .. |. ...|| .  .  . |.... ....... .  . ....   . ..| .||  |.. ..    .   ..  ||| ..  
ksneDavlvvlnllslledlllfgvfDGhgGhaaaevasellvelllellekllllltlsledieealrkaflaadeellelallrpelagsGtTavval

VLLEinkgsdkwspqwEFVCASVGDCKAYLLSQGEVTDITEGNRSNLDAK-----DCGGRLGPHLEQ---------GKPDLR----------------NL
.  .             ...| |||..|.||..||.. .|.  . .         ..||.   .            |  ||                  .
irgn............klyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshgrvngvlavtRalGdfdlklllslllleplvsaePdv

NIFCASVYDEDIIMIVSDGVHDNLDPKHLGKTPNDMS----KefnlngekwtdvdfskalvaknaftaslletlaadstdPNEISNRILEHCW
 ..  .. | |.... |||..|.|... . .  ...                                            ..|..........
tvleltledddfllLasDGlwdvlsneeivdivrsllakgld......................................leeaaeeLvdlAl
PP2Cc_SM00332 338-541 3e-10 33.0 In-house 14-238 (274) alignment 
Range on Protein: 338-541
Range on HMM: 14-238/274.0
PNTTERAGDPIADRYTCAVY----NNRLITCLADGcnwgQKPKEAAQNASTAFIDYVISKNDDMTN--VKEVGKILFNAFECAHKSIMLGKDEFWE---A
 ..   . ... |.. . |     .. |. ...||    .  .|.|. .|  . ......    ..   ..| ..| .||. ... |.  ..  ..    
kssmqgwrksmeDahvvvvdlveeedwlffgvfDG....hgGsevakfvskklpealkeelkkkkdeleddveealkkaflstdeeileeeqskelenal

GTTTLLGGVLLEINkgsdkwspqweFVCASVGDCKAYLLSQGEVTDITEGNRS--------------NLDAKDCGGRLGPHLEQGKPDLR----------
  .|..  .| . .           ...|.|||..|.| ..|....... ..                   .   | |    . |. .|           
sGstavvallkked...........lyvanvGDSravlcrngkavqlsvdhkpedederkRikkaggvvekgrvngglavsrafGdhflkknkklkepyi

--NLNIFCAS-VYDEDIIMIVSDGVHDNLDPKHLGKTPND
    .. . .   ..... ..|||..|.|..... .. ..
taepdvkvvtltsedeflilaSDGlwdvlsnqevvdivrk
DUF904 Protein of unknown function (DUF904) 7-33 7e-06 12.8 Pfam-A 9-36 (72) alignment 
Range on Protein: 7-33
Range on HMM: 9-36/72.0
IEKKYQLLLEENQRLKNEINELKQK-YE
 |.|.| .... . |..||.|||.. ..
LeskiqqAvdtialLqmeieeLkeeneq
PP2C_2 Protein phosphatase 2C 342-533 7.9e-06 18.3 Pfam-A 6-184 (212) alignment 
Range on Protein: 342-533
Range on HMM: 6-184/212.0
ERAGDPIADRYTCAVYNN-RLItCLADGCNWGQKPKEAAQNASTAFIDYVISKNDDMTNVKeVGKILFNAFECAHK------SIMLGkDEFWEAGTTTLL
.|.| |  |...  . .. .|.   |||    .  ...|. | .|..... .. ...   .   ..| .. . ...      . . . .|  ..  ||||
rrkgkpcqDalaireasdgwll.aVADGaGsakrSdkGarlaveaagealeklleeeseqe.eeallrqieneilasvklkqeaeaq.qeelkdyatTll

GGVlleINkgsdK-WspqweFVCASVGDCKA-YLLSQGEVTDITEGNRSNLDAKdcGGRLGPHLEQGKPDLRNLNifcasVYDEDIIMIVSDGVHDNLDP
  |   |.    . .     .|....||. . . ...|||. ..|        .    .| .. .... ..|.|.     . . | .....||| |.| .
lav...it....pge.....ivffqiGDgaivvrdrdgevqllgepdsgeyane..ttfltsedaeeelrirrlk.....lepgdalllmTDGvsdslrk

K
.
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PP2C_2 Protein phosphatase 2C 342-533 7.9e-06 18.3 In-house 6-184 (212) alignment 
Range on Protein: 342-533
Range on HMM: 6-184/212.0
ERAGDPIADRYTCAVYNN-RLItCLADGCNWGQKPKEAAQNASTAFIDYVISKNDDMTNVKeVGKILFNAFECAHK------SIMLGkDEFWEAGTTTLL
.|.| |  |...  . .. .|.   |||    .  ...|. | .|..... .. ...   .   ..| .. . ...      . . . .|  ..  ||||
rrkgkpcqDalaireasdgwll.aVADGaGsakrSdkGarlaveaagealeklleeeseqe.eeallrqieneilasvklkqeaeaq.qeelkdyatTll

GGVlleINkgsdK-WspqweFVCASVGDCKA-YLLSQGEVTDITEGNRSNLDAKdcGGRLGPHLEQGKPDLRNLNifcasVYDEDIIMIVSDGVHDNLDP
  |   |.    . .     .|....||. . . ...|||. ..|        .    .| .. .... ..|.|.     . . | .....||| |.| .
lav...it....pge.....ivffqiGDgaivvrdrdgevqllgepdsgeyane..ttfltsedaeeelrirrlk.....lepgdalllmTDGvsdslrk

K
.
e