Gene DDB_G0279461 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily KAPP-like
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP100_AA protein Get Run
DdisP100_AA_752-1005 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_KAPP-like_pd Subfamily KAPP-like 755-1005 4.3e-147 481.2 In-house 8-266 (266) alignment 
Range on Protein: 755-1005
Range on HMM: 8-266/266.0
KPMEMEDVYLTQYPLGDDQD----SQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNENGGKPIYDMRGVFLNAFKEVDAQLSKFEYEGATATVC
 ..|||||.|..|||.....    |.|||||.||||.|||.|.|||..||..| |..||||...||..|||......||||||||.|..|||||||||..
cstemedvslaiypllkekklsncsnialfavfdGhaGkGaadaakklfpkelekllkstkqddGGdniydqskllenafkevdaklkdfeyeGatatla

LVWRAGHQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEGQTRINGLMVSRALGDHFIKHLNCGLSGEPYVSPPISITPFHSH
|||..|.||..|.||||||.||||.|||.|.|||||.|.||||.||||.|||||...|||||||.|||||||||||.||.||..|||||..|..|||...
lvwsdGqqrylqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsdnqtrinGlavsralGdhfikelniGlisepyvsnrilltpfdkf

LIVASDGLWDVISGNRAMEIVKV----QQTEEKMSNSLLQCAIGSIKAKDNISIIVVTL
||||||||||||||..|.|.||.    |.||.||..|||..||.|||||||.|.|||.|
livasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvkl
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 755-1005 2.1e-145 475.7 In-house 7-276 (276) alignment 
Range on Protein: 755-1005
Range on HMM: 7-276/276.0
KPMEMEDVYLTQYPLGDDQD----SQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKS-----TKNENGGKPIYDMRGVFLNAFKEVDAQLSKFEYEGA
 ..|||||.|..|||.|..|    |.|||||.||||.|||.|.|||..||..|.|..||     ||...||..|||.....|..||||||.|..||||||
cstemedvslaiyplldekdlsncsnialfavfdGhaGkGaadaakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkdfeyeGa

TATVCLVWRAG------HQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEGQTRINGLMVSRALGDHFIKHLNCGLSGEPYVS
|||..|||..|      .||..|.||||||.||||.|||.|.|||||.||||||.||||.|||||...|||||||.|||||||||||.||.||..|||||
tatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsdnqtrinGlavsralGdhfikelniGlisepyvs

PPISITPFHSHLIVASDGLWDVISGNRAMEIVKV----QQTEEKMSNSLLQCAIGSIKAKDNISIIVVTL
..|..|||...||||||||||||||..|.|.||.    |.||.||..|||..||.|||||||.|.|||.|
nrilltpfdkflivasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvkl
0034914 PP2C-like 753-1005 1.1e-48 158.6 In-house 29-290 (295) alignment 
Range on Protein: 753-1005
Range on HMM: 29-290/295.0
AKKPMEMEDVYLTQYPLGDDQDsQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTkNENGGKPIYDMRGVFLNAFKEVDAQLSKFEYE-------GA
  . ...|| .|. ..|  ... ...||..||||.|  .|  |.|.....||......   .   .. |.. .. .||...| .| .  ..       |.
qGrrksneDavlvvlnllslle.dlllfgvfDGhgGhaaaevasellvelllellekl.lllltlsledieealrkaflaadeellelallrpelagsGt

TATVCLVwragHQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEGqTRINGLMVSRALGDHFIK------HLNCGLSGEPYVS
||.|.|.    .....  |||||| |.|. ..| ..|..||. ....|..||.. | . . |  . ..|.|.|||||.. |      .|. ..| ||.|.
Tavvali....rgnklyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshg.rvngvlavtRalGdfdlklllslllleplvsaePdvt

pPISIT-PFHSHLIVASDGLWDVISGNRAMEIVKV----QQTEEKMSNSLLQCAIGsIKAKDNISIIVVTL
  ...| . .  |..||||||||.| . ...||.     ... |.... |.. |.    ..|||...|| |
.vleltledddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAla.rgsrDNiTvvvvrl
PP2Cc_SM00332 754-1003 4.8e-44 143.8 In-house 19-274 (274) alignment 
Range on Protein: 754-1003
Range on HMM: 19-274/274.0
KKPMEMEDVYLTQYPLGddQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNENggkpIYDMRGVFLNAFKEVDAQLSKF--------EYEGA
... .|||.. ..  |   . .. ..|..||||.|. .|  ... .|..| . .|. |.|.      |.  .  .||...| .. .         .  |.
gwrksmeDahvvvvdlv..eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel....eddveealkkaflstdeeileeeqskelenalsGs

TATVCLVWRAGhqrfVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEGqtRING-LMVSRALGDHFIK----HLNCGLSGEPYVSP
||.|.|. .      .  |||||| |.|. ... . ||.||.. |..|..|||. | .   |  |.|| |.||||.|||| |    .   ... || |. 
tavvallkked....lyvanvGDSravlcrngkavqlsvdhkpedederkRikkaggvvekg..rvngglavsrafGdhflkknkklkepyitaepdvkv

pISITPFHSHLIVASDGLWDVISGNRAMEIVKVQQ------TEEKMSNSLLQCAIGSIKAKDNISIIVV
 ...|. .  ||.||||||||.| . . .||. .         ..... | ..|| . ...|||...||
.vtltsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeairrggseDniTvvvv
subfamily_PPM1A_pd Subfamily PPM1A 757-1005 1.2e-43 142.5 In-house 24-280 (282) alignment 
Range on Protein: 757-1005
Range on HMM: 24-280/282.0
MEMEDVYLTQYPLGddQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKY--I--KSTKNENGGKPIYDMRGVFLNAFKEVDAQLSKFEY---EGATATV
.|||| . ..  ||  . .. ..||.||||.|. .|  .|. ... .|.   .  .......  .    .|  ||.. ... .. .. .     |.||..
vemEDahtvvaslg..alkdwsfFavfDGHaGsevakyvkkhllenileeeelkeaaleasekdevkealrqgfLaldeairelstdlktadksGsTavt

CLVWraghQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTegQTRING-LMVSRALGDHFIKH------LNCGLSGEPYVSpPI
.||     .. .  ||.||| |.|. .... ||..||....|.| .||.. | ...    |.|| | |||||||...|.       .  .|.||.|   |
vlvs....ekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkRieqAGGsvv..vsRvnGaLAvsRalGDyeykeeeekkaeeqlvsaepevt.si

SITPFHSHLIVASDGLWDVISGNRAMEIVKVQ----QTEEKMSNSLLQCAIgSIKAKDNISIIVVTL
...  . .|..|.||.|||.| . ..|.|. .    .  |.....|.. |. .  ..||.|..||..
erseeddflvlacDGiwDvlsdeevvelvrkrlevadeleevakalvdkal.ekgsrDNlsvlvvlf
PP2C Protein phosphatase 2C 757-989 4.6e-40 130.8 Pfam-A 13-247 (255) alignment 
Range on Protein: 757-989
Range on HMM: 13-247/255.0
MEMEDVYLTQYPLGD-DQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNEnggkpiyDMRGVFLNAFKE-VDAQLSK------FEYEGATAT
..|||  .   .|.  ...|..|.||.|||| |  .|  |.|  ..|| . .. .. |       . . .. ..| .  | .| .       ...|.||.
ksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflele.......kvekalrksfladtdeelksskantepsksGstav

VCLVWRAGhqrfVQSANVGDSTAFLSYGNETL-FLSKDHRATDPEEIQRIKNDGITLTEgQTRINGL-MVSRALGDHFIKH-LNCGLSGEPYVSpPISIT
|.|..       .. |||||| | |. ....  .|..||...|..|..||...| .. . ..|.||   |||||||...|   ..  | ||.|.  ...|
valirgkk....lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.ngrvngsLavsRalGdfelkpkeeqlvsaePdvt.svklt

PFHSHLIVASDGLWDVISGNRAMEIVKVQQTE----EKMSNSLLQCAI
. .. ||.||||||||.|   |...|. . ..    ..... |.. ||
eedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeai
PP2C Protein phosphatase 2C 757-989 4.6e-40 130.8 In-house 13-247 (255) alignment 
Range on Protein: 757-989
Range on HMM: 13-247/255.0
MEMEDVYLTQYPLGD-DQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNEnggkpiyDMRGVFLNAFKE-VDAQLSK------FEYEGATAT
..|||  .   .|.  ...|..|.||.|||| |  .|  |.|  ..|| . .. .. |       . . .. ..| .  | .| .       ...|.||.
ksmedahialknlekssgkssvaffavfdghggreaakyarehleeilkeqksflele.......kvekalrksfladtdeelksskantepsksGstav

VCLVWRAGhqrfVQSANVGDSTAFLSYGNETL-FLSKDHRATDPEEIQRIKNDGITLTEgQTRINGL-MVSRALGDHFIKH-LNCGLSGEPYVSpPISIT
|.|..       .. |||||| | |. ....  .|..||...|..|..||...| .. . ..|.||   |||||||...|   ..  | ||.|.  ...|
valirgkk....lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.ngrvngsLavsRalGdfelkpkeeqlvsaePdvt.svklt

PFHSHLIVASDGLWDVISGNRAMEIVKVQQTE----EKMSNSLLQCAI
. .. ||.||||||||.|   |...|. . ..    ..... |.. ||
eedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeai
PPM_PTC7 758-988 1.8e-39 128.7 In-house 14-250 (259) alignment 
Range on Protein: 758-988
Range on HMM: 14-250/259.0
EMEDVYLTQYPLGD-DQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNEnggKPIYDMRGVFLN-AFKEVDAQLS---KFEYEGATATVCLV
.|||. .   .|.  . .. .|.||.|||| |  .|  |.|....|| . .  .. |   |..  .|  ||. ...|.  . .   . ...|.||.|.|.
smedahialanlesssgkdsvaffavfdghggreaakyarehleeilkerksfeele...klekalrksflaldtdeelksseantepstsGstAvvali

WRAGhqrfVQSANVGDSTAFLSYGNETL-FLSKDHRATDPEEIQRIKNDGITLT-EGQTRINGL-MVSRALGDHFIKH---LNCGLSGEPYVSpPISITP
.       .. |||||| | |. ....  .|..||......|..||.. | ..  .|..|.||   ||||.||.. |      . .| ||..|  . |..
tgsk....lyvAnvGDSravLcrsgnavkqltedHkpsnedEreRiegaggsvsnvgngrvngvlavsRafGdfelkpketeeqlvsaePdis.stkide

FHSHLIVASDGLWDVISGNRAMEIVKVQQTE---EKMSNSLLQCA
 . .||.||||||||.|   | ..|. .  .   .. .. |.. |
edefliLasdGlwdvvsdqeavdlvrselskkdpmeaaeklvdea
0049733 PP2C-like 756-1005 1.7e-37 122.1 In-house 15-233 (235) alignment 
Range on Protein: 756-1005
Range on HMM: 15-233/235.0
PMEMEDVYLTqyplgddqdsQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKStknenggKPIYDMRGVFLNAFKEVDAQLSKFEYE-------GATAT
  ..|| .|           ...|||..|||.|  ..  | |.....||.....        ...|.. .. .||......| .  ..       |.||.
rkvneDavlv..........glllfavaDGhgghaagevasellvetllellle.......lllldleealrkaflaaneallelalaspelagmgtTav

VCLVWraghQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLtegqTRINGLMVSRALGDHFIKhlncglsgePYVSpPISITPFH
|.|..    ....  |||||| |.|  ... ..|..||. ....| |||.. |  .    . ...|...|||||...|         |.|.  . ..| .
valld....ggklyvanvGDsrayllrdgklvqltedhspvnelerqriitaggav....rvpgrlaltralGdlllk.........pdvt.vlelepgd

sHLIVASDGLWDVISGNRAMEIVKVqQTEEKMSNSLLQCAIGSIKAkDNISIIVVTL
  |..||||||||.| . ......  .. |.. . |.. |.   .  |||...|| |
.flllasDGlwdvlsdeeivdllrs.ldleeaaerlvelalarggr.DNiTvvvvrl
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 758-1005 6.6e-37 120.2 In-house 19-253 (255) alignment 
Range on Protein: 758-1005
Range on HMM: 19-253/255.0
EMEDVYLTQYPLGDDQDSQIalFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNenggKPIYdmrgVFLNAFKEVDAQLSKFE-YEGATATVCLVWRag
 ||| .       |..|...  .|.||||.|.  | .| | ...|| ....  .     .|.     .. .|.||.. |.|.   . |.||.. |. .  
tmedelviyGsfrdksdedy..yalfdGhgGraaakfaseelykilaelldlnna....nPvk....slkkaykeistqiserpkfiGttaasvliie..

hqRFVQSANVGDSTAFLSY-GNETLFLSKDHRATDPEEIQRIKNDGITLTEG--QTRING-LMVSRALGDHFIKHLncgLSGEPYVSPPISITPFHSHLI
   .|  |||||| . |.     .  || ||. ....| .||.. | |. ..   .|.|| | ||||||| |..     .  .|..|  . |.  . .||
..dkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsflePf...vvpdPdlsqsleiskkdkfli

VASDGLWDVISGNRAMEIVKVQQTEEKMSNSLLQCAIGSiKAKDNISIIVVTL
.| ||.||.|| ..|.|||   .  || .. |   |  |  ..||||.||. |
lacdGiwdlisdeeaveivagisdpekaaeklrdlayss.Gstdnisvivikl
subfamily_PPM1E_pd Subfamily PPM1E 755-1005 9.7e-31 99.9 In-house 16-262 (265) alignment 
Range on Protein: 755-1005
Range on HMM: 16-262/265.0
KPMEMEDVYLTQ--YPLGDDQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKSTKNENggkpiydmrGVFLNAFKEVDAQLSKF----EYEGATAT
. ||   | | .    .. ......| ||.||||.|  .|  |..  .. | .  | ...             . .|||..| .. .     .... . .
rkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa.........ealkeafkltDerflqkaereklksGsta

VCLVWRAGHqrfVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIK-NDGITLTEGQTRING-LMVSRALGDHFIKHLncgLSGEPYVSpPISITP
|. . .  .   .. | .||| |.|    |.. | | |.  ...| .||. ..|. .  |. |.|| | ||||.||   |.    .|||. |.  .... 
vvvliekdq...lyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpy...vsgeadva.eveldg

FHSHLIVASDGLWDVISGNRAMEIVKVQQ-----TEEKMSNSLLQCAIgSIKAKDNISIIVVTL
 .  ||.|.||||||.  ......|.        ........|.. |. .  ..|||...|| |
seeylilacDGlwDvvneeevvklveefladgaedlsevakllveaak.eagssDnitvvvvfl
subfamily_PPM1G2_pd Subfamily PPM1G2 757-1005 5.7e-30 97.2 In-house 31-286 (287) alignment 
Range on Protein: 757-1005
Range on HMM: 31-286/287.0
MEMEDVYLTQYP-LGDDQDSQIALFAIFDGHSGKGCAVAAKEIfpniLLKYIKSTKNENGGKpiydMRGVFLNAFKEVDAQLSKF-----EYEGATATVC
..||| ....   |  ..|...||||.|||| |. .|  | .     | |.|.. |. . |.    .. .. .||.|.| .| |      |  |.||.| 
lnmeDahilenelleksddkslalfavfDGhGGakvakyagkk....likkiakkksfkega....leqilkdafletDeellkdeklkdesaGstavvv

LVWRAGhqrfVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEGqtRING-LMVSRALGDHFIKHLNCGLSGEPYV--SPPISITPF
|.        .  ||.||| | ||   ..  || ||. .. .| .||.. | .   .  |.|| | .||||||.  |. .   . |  |   | . ..  
likeek....lyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln..rvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkl

---HSHLIVASDGLWDVISGNRAMEIVKVQQT----EEKMSNSLLQCAIGSIKA-----KDNISIIVVTL
   .  |..| ||.|||.. .  ...|. . .     ......||. ..           ||.....|.|
deddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvvivvl
subfamily_ILKAP_pd Subfamily ILKAP 767-978 1.5e-26 86.3 In-house 33-246 (293) alignment 
Range on Protein: 767-978
Range on HMM: 33-246/293.0
YPLGDDQDSQIALFAIFDGHSGKGCA-VAAKEIFPNILLKYIKsTKNENGGkpiYDMRGVFLNAFKEVDAQLSKFE-------YEGATATVCLVWraghQ
  | ... |... .|.||||.|.  .  ||...  .|| |. | ..  .      ...  ....||..| .. |          .|.||||.||     .
lrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpk.sdvsake...keikkclvdsfkktdeefLklaskakPvWkdGstatvvlvl....d

RFVQSANVGDSTAFLSYGNE------TLFLSKDHRATDPEEIQRIKNDGITLTEGqtRINGLM-VSRALGDHFIKHlnCGLSGEPYVSPpISITPFHSHL
  . .||.||| |.|   .|      .. |.||| ... || .||.  | ....|  |..|.. |||..||   |.  .|..  | |.  . .|.   ..
nvlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdg..rvlGvlevsrsiGdgrfkr..lGvistPdvkk.ceLtendlfv

IVASDGLWDVISGNRAMEIVKVQQTEE
..| ||||.|.| . ... .  .  .|
vlaCdGLwkvfsadevvkfilkvlede
subfamily_PPM1L_pd Subfamily PPM1L 758-1005 1.4e-23 76.5 In-house 18-266 (269) alignment 
Range on Protein: 758-1005
Range on HMM: 18-266/269.0
EMEDVYLTQYPLgdDQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYI-KSTKNENGGKPIyDMRGVFLNAFKEVDAQLS-----KFEYEGATATVCL
.||| .  .  .  ... .. .||.|||| |.  |  ||..... ... . .  .. .  .|| .   .. .    || .|      . .  |.|| . |
rmedrfeieedi..knktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentepi.nfsklltdeilsvdekllekakraediaGttalial

VwragHQRFVQSANVGDSTAFLSY-GNETLFLSKDHRATDPEEIQRIKNDG-ITLTEGQTRINGLM-VSRALGDHFIKHLNCGLSGEPYVSPPISITPfH
|    ... .  ||||||   |     ... || ||.  ...| .|||. | .   .|  |..|.. .||||||. .|. |  ..    ..  .      
v....qesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknlviadpdiltfdlddhk.p

SHLIVASDGLWDVISGNRAMEIVKVQQTEEKMSNSLLQCAIGSIKAKDNISIIVVTL
  ||.||||||| .| . |.. .| .  | ..    |        . |||...||.|
eflilasdGlwdtfsneeavrfikerlkepdfGakslvlesfkrGsvdnitvlvvkl
subfamily_PPM1G_pd Subfamily PPM1G 844-981 1e-21 70.5 In-house 297-435 (473) alignment 
Range on Protein: 844-981
Range on HMM: 297-435/473.0
GATATVCLVwragHQRFVQSANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLTEgQTRIN-GLMVSRALGDHFIKHLNCGLSGEPYVS--P
|.||.|.|.    ... .  ||.||| . ||   . | || ||.  |..| .||.. | ...| . |.| || .|||||||. |. .     |  .|  |
GttAvvaLl....kekklivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiekAGGkvde.dgRvnGGLnlsRAlGDhaYkkneeLplkeqmisAlP

PI---SITPFHSHLIVASDGLWDVISGNRAMEIVKVQQTEEKMS
 |    .|. .  |..|.||.|.|.. .  .. |... .... |
DikvltlteedeFlvlAcDGiWnvmesqevvdfvraklkkgees
subfamily_PPM1K_pd Subfamily PPM1K 774-1005 2.5e-19 62.4 In-house 28-258 (263) alignment 
Range on Protein: 774-1005
Range on HMM: 28-258/263.0
DSQIALFAIFDGHSGKGCAVAAKEIfpniLLKYIKSTKNE-NggkpiyDMRGVFLNAFKEVDAQLSKFE----------YEGATATVCLVwRAGHQRFVq
| ..  .|.||||.|  .|  . .     | | .|  ... .      |.. |. |||.|.| .|...             |.||||.|. | | .  . 
dpellyvavfdGhaGsaaadfvhdk....lekilkrllekek......dleivlknafeeldkklkrylefsvaeaellssGttatvsll.rdGtelvl.

sANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDGITLT---EGQTRING-LMVSRALGDHFIKHlnCGLSGEPYVSpPISI-TPFHSHLIVASDG
 |..||| | |    ..  |..||     || .|||. | ...    |. ..|| | ..|.|||  .|.   |.  .|     . .     | |.. .||
.aslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGdldlkr..yGviatPetk.slkvdhaadsflvlitdg

LWDVISGNRAMEIVKVQQTEEKMSNSLLQCAIgSIKAKDNISIIVVTL
. .|.. .   ..|.. .  |. ...| ..|.    ..|| ...|| |
isfvvnsqelcdlvrlchdpeeaahalteqal.qygsednatavvvpl
subfamily_PPM1D_pd Subfamily PPM1D 759-1005 6.8e-19 61.1 In-house 16-307 (309) alignment 
Range on Protein: 759-1005
Range on HMM: 16-307/309.0
MEDVYLTQYPLGD-DQDSQIALFAIFDGHSGKGCAVAAKEIFPNILLKYIKStKNENGGKPIYDMRGVFLNAFKEVDAQLSKFEY------EGATATVCL
||||   ..   .  .. . | .|.|||| ||  |  |.|   . . |  |   ...  . .  .|  ||.  ...  .|... .        | .|. .
meDvvaivleeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkf.lssepedvleAireaflatheamkkkleeWpktksgllstaGttasv

VWRAGHQRFVqsANVGDSTAFLSYGNE------TLFLSKDHRATDPEEIQRIKNDGI--TLTEG---------------Q---TRINGLMVSRALGDHFI
|   ... .|  |.||||...|.. ..      .  | |||.  .||| .||.. |   .  .|               .   ..|  | |.|.||| . 
viirreklyv..ahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvvWkRprlehngptvideiPFLavaRslGDlWs

KHLN---CGLSGEPYVSPPISITPFHSHLIVASDGLWDVISGNRAMEIVKVQQTEEKM--------SNSLLQCAIGSIKA----KDNISIIVVTL
   .      | ||.|.     .  . ..|.||||||.|.... |...|. ... ...        .. |...|..  ..     ||.|.|||.|
ynaksgefvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklraDnvsvivvil
PPM_PTC7_SpoIIE 758-972 1.2e-14 47.7 In-house 14-206 (230) alignment 
Range on Protein: 758-972
Range on HMM: 14-206/230.0
EMEDVYLTQYPLGD-DQDSQIALFAIFDGHSGKGcAVAAKEIFpNILLKYIkSTKNEnggkpiydmrgVFLNAFKEVDAQL----SKF-EYEGATATVCL
.|||.     ...  . ..  ......||| |   |.|....  ..| ...  .  |              ..... ...|     .. .  ||||.|.|
smedahispansekssggrlalvvgdvdGhGgra.alamgllr.talrela.fagle...........kpeeilrrlnlalaadledepsssgaTavval

vwRAGHQRFVQSANVGDSTAFLSYGNETlflskdhratdpeEIQRIKNDGIT-LTEGQTRINGL-MVSRALGDHFIKHLNCGLSGEPYvSPPISITPFHS
    .... .  ||.||| ..|. ....             |. ||.  |   |  . .|..|   ||.| || ....     . ||. .. .     . 
..idpstgklyvanaGdsppllvrddgg.............ererivagglpslGilpgrvfgvlavslapGdllllytDGvveaepd.tsdgelfgkde

HLIVASDGLWDVISGNRAMEIVK
.||.|||||||| |   ....|.
flilasdglwdvlspqelvdlvr
subfamily_PP2D1_pd Subfamily PP2D1 864-973 1.6e-13 43.2 In-house 193-304 (492) alignment 
Range on Protein: 864-973
Range on HMM: 193-304/492.0
ANVGDSTAFLSYGNETLFLSKDHRATDPEEIQRIKNDG--ITLTEGQTRINGLM-VSRALGDHFIKHLNCGLSGEPYVSpPISITPFHSHLIVASDGLWD
||.|.  | |  . ..  | ..|   ...| .|... |  .. .| ....||.. . | || .   .|.  .  ||..   . ..     |..|| |||.
anaGnvqAvLcreGkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGnyGdpkLkksvipePktt.svkldeaaqflvlAsnGlWe

VISGNRAMEIVKV
|.| .  ...|| 
vlseeevlsLvkq
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 779-923 3.8e-12 39.3 In-house 23-183 (292) alignment 
Range on Protein: 779-923
Range on HMM: 23-183/292.0
LFAIFDGHSGKGCAVA--AKEIFPNILLkyikSTKNENGGKPIYDMRGVFlNAFKEVDAQLSKFEYEGATATVCLVWRAGHQRFVqsANVGDSTAFLSY-
| |..|||  .| .||  |.. .   ||    .. ...   .   . ..  .   ..|    .   ...||.|| . | ... ..  |||||| | |   
laavldGhGvnGdkvaqlaedtlevell....eltrqlqelsealllril.diaakldkltidaresattavvcarvrddralil..anvGdsrallgrc

----GNETLFLSKDHRATDPEEIQRIKNDGITLT---------EGQTRI-------NGLMVSRALGDH
     .|   ||.||.  ||.| .||.. |  ..         .| .|.        .| .|||||| 
lggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGdf
subfamily_PDP_pd Subfamily PDP 843-983 5.9e-09 28.5 In-house 152-320 (398) alignment 
Range on Protein: 843-983
Range on HMM: 152-320/398.0
EGATATVCLVwrAGHQrfVQSANVGDSTAFLSYGNE-----TLFLSKDHRATDPEEIQRIKNDGITLTE----GQTRIN-GLMVSRALGDHFIKHLN---
 ||.|.. |.   |..  .  ||.||. | |   .|     .  ||||. |. .||..|||..     .     . |.   |. .|| ||   |  .   
sGacallali..egte..lhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLqPlRAFGdvryKwseelq

-CGLSG------EP--YVSPPI----------SITPFHSHLIVASDGLWDVISGNRAMEIVKVQQTEEKMSNS
   |.       ||  | .||            ...    |..|.|||||..| . ....|.   ...| ...
kkvlekaylkvlepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkkekep
PP2C_SIG_SM00331 779-1004 4.2e-08 26.0 In-house 32-216 (217) alignment 
Range on Protein: 779-1004
Range on HMM: 32-216/217.0
LFAIFDGHS-GKGCAVAAKEIFPNiLLKYIKSTknenggkpiydmrGVFLN-----------AfkevdaqlSKFEYEGATATVCLVwrAGHQRFVQSANV
|....||.  |.  |.|.... .  | ......               . .                    ....  .||....|.     .. .. ||.
llvvaDgmGkGlaAaaassqlrta.lrellseg.............eelsqalkrlnraiyee........keekgmfaTlllaly..dfssgklsyana

GDSTAFLSYGNETLFLSKDhratdpeeiqrikndgitltegqtringlmvsralgdhfIKHLNCGLSGEPY-VSPPISITPfHSHLIVASDGLWDVISG-
|||  .|   ... .  ||                                       ...   ||  |.   .  ... .  . |. ..|||... |  
Gdsrpyllrdgklveilkd.......................................vegaplGlepevsvdirelelek.gdllllytDGltearsek

----NRAMEIVKVQ--QTEEKMSNSLLQCAIGSIKAK---DNISIIVVT
     | .||..    .. ...... ..... ..|..   |.|...|| 
gfaeerleeiledlvdseaqelaqkiveellelakgsngeDdiTvvvvk
subfamily_PPM1H_pd Subfamily PPM1H 911-973 1.3e-07 23.8 In-house 278-349 (404) alignment 
Range on Protein: 911-973
Range on HMM: 278-349/404.0
INGLMVSRALGDHFIKHLNCGLSGEPYVSP--PISITPFHS-------HLIVASDGLWDVISGNRAMEIVKV
.. . |.| |||| .| ....||  |..||   .... ...        ||.|.||||||.| ... |||. 
latigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivre