Gene DDB_G0282105 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPM
Superfamily PPM
Family PPM
Subfamily KAPP-like
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP101_AA protein Get Run
DdisP101_AA_681-958 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Dicty-PPM-1_pd Subfamily Dicty-PPM-1 683-958 4.7e-173 566.4 In-house 1-276 (276) alignment 
Range on Protein: 683-958
Range on HMM: 1-276/276.0
KKLSPGCSTMMEDVSIAIYPFLKEKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLTEQDDGGDNNHNQSKLLNDLFSNVDNKMKD
|||||||||.|||||.||||.|.||.|||||||.||.|||||||.||||.|.||||||.||||.|||||||.|||||||...|||||.|||..||.|.||
kklspgcstemedvslaiyplldekdlsncsnialfavfdGhaGkGaadaakklfpkelekllksgnysltkqddGGdniydqskllldlfkevdaklkd

HEYEGCTATLALIWSDGEEQQQQQQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSDNQTRINGVAVSRSLGNHFIKEQNIGMI
.||||.||||||.|||||||||||||||||.|||||||||.|||||.||..||||.||.|||||||.||..|||||||||.||||.||.|||||.|||.|
feyeGatatlalvwsdGeeqqqqqqrylqvanvGdssaflsrGneslelskdhkatdpeekqrikddGitlsdnqtrinGlavsralGdhfikelniGli

STPHISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQSSLCKDNVTVIIVKL
|.|..|||.||||.|||.|.|||||||||.||||||||.|||||.||.|.|||.||||||||...||||.||.|||
sepyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvkl
subfamily_KAPP-like_pd Subfamily KAPP-like 682-958 1.1e-160 525.8 In-house 1-266 (266) alignment 
Range on Protein: 682-958
Range on HMM: 1-266/266.0
KKKLSPGCSTMMEDVSIAIYPFLKEKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESgnyslTEQDDGGDNNHNQSKLLNDLFSNVDNKMK
||||||||||.|||||.||||.||||||||||||.||.|||||||.||||.|.||||||.||||.|     |.|||||||...|||||...|..||.|.|
kkklspgcstemedvslaiypllkekklsncsnialfavfdGhaGkGaadaakklfpkelekllks.....tkqddGGdniydqskllenafkevdaklk

DHEYEGCTATLALIWSDGeeqqqqQQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSDNQTRINGVAVSRSLGNHFIKEQNIGM
|.||||.||||||.||||      |||||||.|||||||||.|||||.||..||||.||.|||||||.||..|||||||||.||||.||.|||||.|||.
dfeyeGatatlalvwsdG......qqrylqvanvGdssaflsrGneslelskdhkakdpeekqrikddGitlsdnqtrinGlavsralGdhfikelniGl

ISTPHISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQSSLCKDNVTVIIVKL
||.|..|||.||||.|||.|.|||||||||.||||||||.|||||.||.|.|||.||||||||...||||.||.|||
isepyvsnrilltpfdkflivasdGlwdvisGkdaiekvkslydqqatedkmasslletaiqsikakdnvsvivvkl
0034914 PP2C-like 687-958 2.9e-54 176.9 In-house 29-290 (295) alignment 
Range on Protein: 687-958
Range on HMM: 29-290/295.0
PGCSTMMEDVSIAIYPFLKEKKlsncsNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLTEQddggdnNHNQSKLLNDLFSNVDNKMKDHEYE
 |..  .||  ......|   .     ...|||||||| |  ||. ||.|..... .|||.  ..||.        ..  . | . | ..|... .. ..
qGrrksneDavlvvlnllslle.....dlllfgvfDGhgGhaaaevasellvelllellekllllltls......ledieealrkaflaadeellelall

-------GCTATLALIWSDgeeqqqqqqrYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSDNqtRINGV-AVSRSLGNHFIKEQ-
       |.||..|||...          .| |.||||| |.|.|..| . ||.||| ....|..||.. |  ||..  |.||| ||.|.|| .. | . 
rpelagsGtTavvalirgn..........klyvanvGDSravllrngelvqltvdhkpvnelererilsaggavshg..rvngvlavtRalGdfdlklll

-----NIGMISTPHISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQsSLCKDNVTVIIVKL
     . .....|... . |  ..|.|...||||||||.. ..... |.||. .| ... .|  |.. |..   ..||.||..|.|
slllleplvsaePdvtvleltledddfllLasDGlwdvlsneeivdivrsllakgldleeaaeeLvdlAla.rgsrDNiTvvvvrl
PP2Cc_SM00332 682-956 4.5e-51 166.8 In-house 7-274 (274) alignment 
Range on Protein: 682-956
Range on HMM: 7-274/274.0
KKKLSPGC------STMMEDVSIAIYPFLkekklsNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLteqddggdnNHNQSKLLNDLFSN
...||.|.       . |||. . .  .       . .. ..|||||||.|  .|. .|| .|. ... |.. .  |         ...  ..|.. |..
nlglsygkssmqgwrksmeDahvvvvdlv......eeedwlffgvfDGhgGsevakfvskklpealkeelkkkkdel.........eddveealkkafls

VDNKMKDHE--------YEGCTATLALIWSDGeeqqqqqqryLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSDNqtRING-VAVS
.|... ..|          |.||..||.  .           | | ||||| |.|||......|. |||..|..|..|||..|  |...  |.||  |||
tdeeileeeqskelenalsGstavvallkked..........lyvanvGDSravlcrngkavqlsvdhkpedederkRikkaggvvekg..rvngglavs

RSLGNHFIK----EQNIGMISTPHISNRYLlTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGA--TADSMASCLLETAIQSSLCKDNVTVIIV
|..| || |    ..  .....|...   | |..|.|.|.||||||||.. ..... | .| ..|.   .. .|  | | ||..  ..||.||..|
rafGdhflkknkklkepyitaepdvkvvtl.tsedeflilaSDGlwdvlsnqevvdivrkllakgktndpqeaaelldeeairrggseDniTvvvv
PP2C Protein phosphatase 2C 688-950 3e-49 160.9 Pfam-A 10-254 (255) alignment 
Range on Protein: 688-950
Range on HMM: 10-254/255.0
GCSTMMEDVSIAIYPFLKEkklSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSlteqddggdnnhNQSKLLNDLFSN-VDNKMK-----
|... |||  ||. .. |.   |  |....|.|||||.|| ||. |..  .. ...  .                 . .|.|.. | .  |...|     
garksmedahialknleks...sgkssvaffavfdghggreaakyarehleeilkeqksflele............kvekalrksfladtdeelksskan

-DHEYEGCTATLALIWSDGeeqqqqqqryLQVGNVGDSSAFLCRGNESI-ELTFDHKANDPSEKQRIKDQGIPVSDnQTRINGV-AVSRSLGNHFIKEQ-
  ....|.||..|||...           |.| ||||| | |||..... |||.|||..|..|..||...|  ||. ..|.||. ||||.|| ...|.. 
tepsksGstavvalirgkk..........lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.ngrvngsLavsRalGdfelkpke

NIGMISTPHISNRYLlTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQsSLCKDN
.  ... |... . | |..|.|.|.||||||||.. ..|.. | |  ... ... .|  |.. ||. . ..||
eqlvsaePdvtsvkl.teedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaia.rgsedn
PP2C Protein phosphatase 2C 688-950 3e-49 160.9 In-house 10-254 (255) alignment 
Range on Protein: 688-950
Range on HMM: 10-254/255.0
GCSTMMEDVSIAIYPFLKEkklSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSlteqddggdnnhNQSKLLNDLFSN-VDNKMK-----
|... |||  ||. .. |.   |  |....|.|||||.|| ||. |..  .. ...  .                 . .|.|.. | .  |...|     
garksmedahialknleks...sgkssvaffavfdghggreaakyarehleeilkeqksflele............kvekalrksfladtdeelksskan

-DHEYEGCTATLALIWSDGeeqqqqqqryLQVGNVGDSSAFLCRGNESI-ELTFDHKANDPSEKQRIKDQGIPVSDnQTRINGV-AVSRSLGNHFIKEQ-
  ....|.||..|||...           |.| ||||| | |||..... |||.|||..|..|..||...|  ||. ..|.||. ||||.|| ...|.. 
tepsksGstavvalirgkk..........lyvAnvGDSravLcrkdnakkeltedHkpsdedEreRIeeaggsvsn.ngrvngsLavsRalGdfelkpke

NIGMISTPHISNRYLlTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQsSLCKDN
.  ... |... . | |..|.|.|.||||||||.. ..|.. | |  ... ... .|  |.. ||. . ..||
eqlvsaePdvtsvkl.teedefliLasdGlwdvlsdqeavdlvrselskkkspmeaaeelvdeaia.rgsedn
PPM_PTC7 688-950 2.2e-48 158.0 In-house 10-258 (259) alignment 
Range on Protein: 688-950
Range on HMM: 10-258/259.0
GCSTMMEDVSIAIYPFLKEkklSNCSNIGLFGVFDGHAGRGAADSASKLFPkeiEKLLESGNYSLTEqddggdnnhNQSKLLNDLFSN--VDNKMKD---
|..  |||. ||  .. ..   |  .....|.|||||.|| ||. |.. ..   |.| |.     .|         . .| |.. | .   |...|.   
gfrksmedahialanless...sgkdsvaffavfdghggreaakyarehle...eilkerksfeele.........klekalrksflaldtdeelkssea

---HEYEGCTATLALIWSDGeeqqqqqqryLQVGNVGDSSAFLCRGNESI-ELTFDHKANDPSEKQRIKDQGIPVS-DNQTRINGV-AVSRSLGNHFIKE
   ....|.||..|||...           |.| ||||| | |||..... .||.|||.....|..||.. |  || ....|.||| ||||..| .. |.
ntepstsGstAvvalitgsk..........lyvAnvGDSravLcrsgnavkqltedHkpsnedEreRiegaggsvsnvgngrvngvlavsRafGdfelkp

---QNIGMISTPHISNRYlLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGaTADSMASCLLETAIQsSLCKDN
   .    ...|.|| .  ....|.|.|.||||||||.. ..|.. | |  ... ...  |  |...||. . ..||
keteeqlvsaePdisstk.ideedefliLasdGlwdvvsdqeavdlvrselskk.dpmeaaeklvdeaia.rgsedn
subfamily_PPM1A_pd Subfamily PPM1A 689-958 1.7e-46 151.9 In-house 22-280 (282) alignment 
Range on Protein: 689-958
Range on HMM: 22-280/282.0
CSTMMEDVSIAIypflkeKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKllesgNYSLTEQDDGGDNNHNQSKLLNDLFSNVDNKMKD--HEY-
  . |||  ...      ..|.. .. ..| |||||||. .|. ..| ....| .     . .|.|.    ..... .. |.. | ..|.....  ... 
wrvemEDahtvv......aslgalkdwsfFavfDGHaGsevakyvkkhllenile.....eeelkeaaleasekdevkealrqgfLaldeairelstdlk

----EGCTATLALIWsdgeeqqqqqQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSdnQTRING-VAVSRSLGNHFIKE----
     |.||. .|.           ...| . |.||| |.|||..... || |||...|.||.||.. |  |     |.||  ||||.|| ...||    
tadksGsTavtvlvs..........ekhliianlGDsRavlcrngkaaflteDHkpsrpkEkkRieqAGGsvv..vsRvnGaLAvsRalGDyeykeeeek

--QNIGMISTPHISNrYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQSSlCKDNVTVIIVKL
  ..  ... |..      . .|.|...|.||.|||.. ....| | . ....  . ..|. |...|..    .||..|..| .
kaeeqlvsaepevts.ierseeddflvlacDGiwDvlsdeevvelvrkrlevadeleevakalvdkalekg.srDNlsvlvvlf
0049733 PP2C-like 688-958 2.8e-40 131.1 In-house 12-233 (235) alignment 
Range on Protein: 688-958
Range on HMM: 12-233/235.0
GC-STMMEDVSIAiypflkekklsncsNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESgnyslteqddggDNNHNQSKLLNDLFSNVD-------NK
|.  . .||  ..              ...||.|.||| |  |.. ||.|... . .||..             . ..  ..| . |  ..        .
grvrkvneDavlv..............glllfavaDGhgghaagevasellvetllellle............lllldleealrkaflaaneallelala

MKDHEYEGCTATLALIWSDgeeqqqqqqrYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVsdnqTRINGVAVSRSLGNHFIKeqni
 ... . |.||..||....          .| | ||||| |.|.|... . ||.||. ... |.|||.. |  |    . ... |..|.||....|    
spelagmgtTavvalldgg..........klyvanvGDsrayllrdgklvqltedhspvnelerqriitaggav....rvpgrlaltralGdlllk....

gmistPHISnRYLLTPQDkFVIIASDGLWDVINGKDAIEKVSSlydqgATADSMASCLLETAIQSSLCkDNVTVIIVKL
     |... .. |.|.| |...||||||||.. ..... ..|      ... .|..|.|.|..   . ||.||..|.|
.....pdvt.vlelepgd.flllasDGlwdvlsdeeivdllrs.....ldleeaaerlvelalarggr.DNiTvvvvrl
subfamily_LRR-PP2C_pd Subfamily LRR-PP2C 691-958 3.8e-37 120.9 In-house 18-253 (255) alignment 
Range on Protein: 691-958
Range on HMM: 18-253/255.0
TMMEDvSIAIYPFLKEKKLSNCsniglFGVFDGHAGRGAADSASKLFPKEIEKLLESgnyslteqddggdNNHNQSKLLNDLFSNVDNKMKDHE-YEGCT
. ||| ...||   ..|. ..      . .||||.|| ||. ||. ..| ...||.              || |  | |.. . ... .....  . |.|
ptmed.elviyGsfrdksdedy.....yalfdGhgGraaakfaseelykilaelldl.............nnanPvkslkkaykeistqiserpkfiGtt

ATLALIWSDgeeqqqqqqrYLQVGNVGDSSAFLC-RGNESIELTFDHKANDPSEKQRIKDQGIPVSDN--QTRING-VAVSRSLGNHFIKEQnigMISTP
|. .||  |          .  . ||||| . || .   .  |..||| ...||..||.. |  |  .   .|.|| .||||.||. |..     ... |
aasvliied..........kvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsflePf...vvpdP

HISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDqgatADSMASCLLETAIQsSLCKDNVTVIIVKL
..|. .  . .|||.|.| ||.||.|  ..|.| | .  |    ..  |  | . | . |  .||..||..||
dlsqsleiskkdkflilacdGiwdlisdeeaveivagisd....pekaaeklrdlays.sGstdnisvivikl
subfamily_PPM1G2_pd Subfamily PPM1G2 691-958 1e-35 116.1 In-house 31-286 (287) alignment 
Range on Protein: 691-958
Range on HMM: 31-286/287.0
TMMEDVSIAIYPFLKEKklsNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKllesgnyslteqdDGGDNNHNQSKLLNDLFSNVDNKMKDH-----EY
  |||  |    .|...   . ... ||.||||| |. .| .|.| . | |.|                 .. . ...|.| | ..|...  .     | 
lnmeDahilenelleks...ddkslalfavfDGhGGakvakyagkklikkiak.............kksfkegaleqilkdafletDeellkdeklkdes

EGCTATLALIwsdgeeqqQ--QqqryLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVSDNqtRING-VAVSRSLGNHFIKEQN----
 |.||. .||        .  .    | |.|.||| | |.   ..  |.|||| .. |||.||...|  |. |  |.|| .|.||.||..  |...    
aGstavvvli........keek....lyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln..rvngnLalsralgDfefkknvkkkp

--IGMISTPHISNRYLLtPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAIQS-----SLCKDNVTVIIVKL
    .  .| .  . |  ..| |...| ||.|||.. |. .. | .   .||. |.... ||.....      ..  ||.||.|| |
eeqivtavPDvlvkkld.eddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvvivvl
subfamily_PPM1E_pd Subfamily PPM1E 692-957 3.2e-35 114.6 In-house 17-261 (265) alignment 
Range on Protein: 692-957
Range on HMM: 17-261/265.0
MMEDVSIAIYPFLKEKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLteqddggdnnhnqsKLLNDLFSNVDNKM-----KDHEYE
 |||  .|.  . .  .|.. ...  |.|||||.|  ||. |..  .. . .  .  . ..              . |.. | ..|...     ...   
kmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa..............ealkeafkltDerflqkaereklks

GCTATLALIwsdgeeQ--QqqqqryLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQG-IPVSDNQTRINGV-AVSRSLGNHFIKEQnigMI
|.||  .||      .  |      |.|. .||| |.|.|  | ..|.  || ... ||.||.. | . |  .. |.||| .|||..|.   |.    ..
Gstavvvli......ekdq......lyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpy...vs

STPHISNrYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGA-TADSMASCLLETAIQSSlCKDNVTVIIVK
. . ... . |. .....|.|.||||||.| ..... |..   .|| . ...|  |.|.|..    .||.||..| 
geadvae.veldgseeylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeag.ssDnitvvvvf
subfamily_ILKAP_pd Subfamily ILKAP 690-957 4.7e-32 104.3 In-house 16-291 (293) alignment 
Range on Protein: 690-957
Range on HMM: 16-291/293.0
STMMEDVSIAIYPFLKEKK--LSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLTEQDdGGDNNHNQSKLLNDLFSNVDNKMKDHEYEG
   |.|. . .  . .. .   |. |..  ..|||||||. |.. |.. . |.| . | ... | .|..       .  |  .. | .  .| |    .|
reemqdahviledldeqlrlekslvsrvsyyavfdGhaGsrasefaaeklhkkileklpksdvsakeke.ikkclvdsfkktdeefLklaskakPvWkdG

CTATLALIWSDgeeqqqqqqrYLQVGNVGDSSAFLCRGNES------IELTFDHKANDPSEKQRIKDQGIPVSDNqtRINGV-AVSRSLGNHFIKeqNIG
.|||. |.  .           | |.|.||| |.|.| .|.      . || ||.. .  |..||.  |  | |.  |..||  ||||.|.   |  ..|
statvvlvldn..........vlyvanlGdskavlvrkkeegdkiasvvLtkdhtpvkyeerkriqkaGgvvrdg..rvlGvlevsrsiGdgrfk..rlG

MISTPHISnRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATAD--------SM--------ASCLLETAIQSSlCKDNVTVIIVK
.||||... .  ||. |.||..| ||||.|.. ..... .... ..  . .        |         .  |   |..   . |||||..||
vistPdvk.kceLtendlfvvlaCdGLwkvfsadevvkfilkvledeeddrkikeeekkskeevrfevacnrlaseavkrg.ssdnvtvllvk
subfamily_PPM1L_pd Subfamily PPM1L 703-958 3.4e-31 101.5 In-house 23-266 (269) alignment 
Range on Protein: 703-958
Range on HMM: 23-266/269.0
FLKEKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLL-ESgnysltEQDDGGDNNHNQSKLLNDLFSNVDNKMKD-----HEYEGCTATLALIw
|  |....|  .. .|.||||| |  ||. | ....|.| . | |       ..|       | ||||.|    ||.|. .     ..  |.|| .||. 
feieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel......dadkentepinfsklltdeilsvdekllekakraediaGttalialv.

sdgeeqqqqQQRYLQVGNVGDSSAFLCRGN-ESIELTFDHKANDPSEKQRIKDQGIPVSDN-QTRINGV-AVSRSLGNHFIKEQNIgMISTPHISNRYLL
         |.. | | |||||   |.  . ..| |.|||| ... |..|||. |  .. .   |..|| |.||.||.. .|..|. .|..| |    | 
.........qesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknl.viadpdiltfdld

TPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQG-ATADSMAsclLETAIQSslCKDNVTVIIVKL
  . .|.|.||||||| .  ..|.. .    ..    | |..   ||.  .   . ||.||..|||
dhkpeflilasdGlwdtfsneeavrfikerlkepdfGakslv...lesfkrG..svdnitvlvvkl
subfamily_PPM1K_pd Subfamily PPM1K 714-957 3e-27 88.4 In-house 30-257 (263) alignment 
Range on Protein: 714-957
Range on HMM: 30-257/263.0
NIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNySLTEQDDG--GDNNHNQSKLLNDLFSNVdnkmkDHEYEGCTATLALIwSDGEEqqqqqqryLQ
..  ..|||||||  ||| . . . | ...|||  .  | .       . ... .. |. ....      ...  | |||..|.  || |        | 
ellyvavfdGhaGsaaadfvhdklekilkrllekek.dleivlknafeeldkklkrylefsvaea.....ellssGttatvsll.rdGte........lv

VGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPV---SDNQTRINGV-AVSRSLGNHFIKEqnIGMISTPHISNRYLLTPQDKFVIIASDGL
. ..||| | |||  ..  || ||. .   ||.|||  |  |   | .. ..||. |..||||.  .|.   |.|.||.  .  .   .| |... .||.
laslGdsrailcrnGkakkltrdhdPeleeekerikaagGsvewnslgkplvngrlamtrslGdldlkr..yGviatPetkslkvdhaadsflvlitdgi

WDVINGKDAIEKVSSLYDQGATadsmASCLLETAIQSSlCKDNVTVIIVK
 .|.| ..  . |.   |   .    |. | |.|.|   ..||.|...| 
sfvvnsqelcdlvrlchdpeea....ahalteqalqyg.sednatavvvp
subfamily_PPM1G_pd Subfamily PPM1G 604-957 1.7e-22 73.1 In-house 139-469 (473) alignment 
Range on Protein: 604-957
Range on HMM: 139-469/473.0
SNISVSNLDNFLKTNNNNNKNNIEESNNNNNNNNNNNNNNNNNNNNNNNNNKNDNKEVNSKLEFSIKDEENKIGLR--------------------RAKK
..|....| . |. .......  .  .............................|| ..| . .......| .                       ...
aeipldellkrldgdgsekeelsqallegaasedeedededeeeeeeekdteeeskeeekkakaakegkqekkeedesekeeeeeekeeeeedekgetee

KLSPgcstmmedvsiaiypflkekklsncsniglfgvfdghagrgaaDSASKlfPKEIEKLLESGNYSLTEQDDGGDNNHNQSKLLNDLFSNVDNKMKDH
. ..                                           |....   .| |.  | .. .  |.|. ....... .. .   .  ..| .  
eeee...........................................dedee..eeedeeeaeeeeeeedeedeeeeeedgegeeakeeldgseekeepG

EYEGCTATLALIwsdgeeqqqqQQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPVsDNQTRING-VAVSRSLGNHFIKEQNI---
|  |.||. ||.          ... | | |.||| . |.|  . ..|  ||| .|. |..||.  |  | | . |.|| . .|| ||.|. |...    
edsGttAvvaLl..........kekklivAnaGDsRcvlsrnGkAldlslDHkPeDevEleRiekAGGkv.dedgRvnGGLnlsRAlGDhaYkkneeLpl

--GMIS-TPHISNRyLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGA--TADSMASCLLETAIQSSL-----CKDNVTVIIVK
   |||  | |  . .||..|.|...|.||.|.|.. .. .. | .   .|   .  ..   ||.... ..        || ||||| 
keqmisAlPDikvl.tlteedeFlvlAcDGiWnvmesqevvdfvraklkkgeesvlseiveeLlDaclapdtsgDGtGCDnmtviivl
subfamily_PPM1D_pd Subfamily PPM1D 688-957 1.8e-22 72.9 In-house 11-306 (309) alignment 
Range on Protein: 688-957
Range on HMM: 11-306/309.0
GCSTMMEDVSIAIypfLKEKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEK---LLESGNYSLTEQDDGG-DNNHNqsKLLNDLFSNVDNKMKDH
|   .||||       |.|.. ..  .   ..||||| |. ||  |..   ..|.|   .| | . ...|  . .  . |.  .. . | . . .| .. 
GgrkymeDvvaiv...leeeesaeelevafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflathe..amkkkleeWpktksgll

EYEGCTATLALIwsdgeeqqqqQQRYLQVGNVGDSSAFLCRGNE------SIELTFDHKANDPSEKQRIKDQGIPVSDN-----------------Q---
   | ||.. .|          ... | |..||||...|   ..      . ||| ||| ..|.||.||.. |  |...                 .   
staGttasvvii..........rreklyvahvGDsaivlgvkepkekklrakeltkdHkPespeekerieelGGevaaksGvkRvvWkRprlehngptvi

TRINGVAVSRSLGNHFIKEQNIGM--I-STPHISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGAT----ADSMASCLLETAIQS----SL
..|  .||.||||. .  ... |.  .   |....| | . ..||.|.||||||.|....||.. |..   .. .      |.|..|...|.|      |
deiPFLavaRslGDlWsynaksgefvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskkl

CKDNVTVIIVK
  |||.||.| 
raDnvsvivvi
PPM_PTC7_SpoIIE 688-927 1.2e-20 67.3 In-house 10-212 (230) alignment 
Range on Protein: 688-927
Range on HMM: 10-212/230.0
GCSTMMEDVSIAIYPFLKEkklSNCSNIGLFGVFDGHAGRGaaDSASKLFPKEIEKLLeSGNYSlteqddggdnnhNQSKLLNDLFSNVDNKMKDH-EYE
|..  |||. |.  .. |.   |  .   ..|..||| ||     |..|. . ...|    . .            . ...|..|. ... ...|  .  
garksmedahispanseks...sggrlalvvgdvdGhGgra..alamgllrtalrela.fagle............kpeeilrrlnlalaadledepsss

GCTATLALIWSDGeeqqqqqqRYLQVGNVGDSSAFLCRGNESieltfdhkandpsEKQRIKDQGIP-VSDNQTRINGV-AVSRSLGNHFIKEQNIGMIST
|.||..||| ..         . | | |.||| ..|.|...              |. ||.  | | ..   .|..|| |||.. |  ...       . 
gaTavvalidpst........gklyvanaGdsppllvrddgg.............ererivagglpslGilpgrvfgvlavslapGdllllytDGvveae

PHiSNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQG
|. . . .|   |.|.|.|||||||| . ......| .  .. 
pd.tsdgelfgkdeflilasdglwdvlspqelvdlvrdelekp
subfamily_PP2D1_pd Subfamily PP2D1 797-925 6.9e-20 64.2 In-house 177-307 (492) alignment 
Range on Protein: 797-925
Range on HMM: 177-307/492.0
SDGEEQQQQQQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPSEKQRIKDQGIPV--SDNQTRINGV-AVSRSLGNHFIKEQNIGMISTPHISNrYLL
|.|.| .....  | . |.|.  | |||. ..| || .|  ... |..|.. .|  |  |......||.  . | |||.   . .  .|  |..     |
sngsevhleelgvlyianaGnvqAvLcreGkaiiLtreHtprnkkERtRvekagsvvvkseknglvnGildttRGLGnyGdpkLkksvipePktts.vkl

TPQDKFVIIASDGLWDVINGKDAIEKVSSLYD
. ...|...|| |||.|..  . .. | ..  
deaaqflvlAsnGlWevlseeevlsLvkqtla
subfamily_PHLPP_pd Subfamily PHLPP 764-958 8.2e-19 60.5 In-house 62-245 (246) alignment 
Range on Protein: 764-958
Range on HMM: 62-245/246.0
NQSKLLNDLFSNVDNKMKD-HEYEGCTATLALIWsdGEEQQQQQQRYLQVGNVGDSSAFLCRGNESIELTFDHKANDPsEKQRIKDQGIPVsDNQTRING
|. . ..  .  . .|.    |  | .| | ||    .. .  .   |.| .||  .| |.|... . |.  .. ..  | .|||..   . ... .|||
neeeymkntllvaqrklGeaGeklgsaallilir..hdkvdPaksfsLevAsvGtlqavliRngkklrlsksyviekd.elkrikeakaii.tednking

-VAVSRSLGNHFIKEQnigMISTPHISNrYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSmasclLETAIQSSLCKDNVTVIIVKL
 .. .| ||  |.      .. .||...  |||.|| ..|. .. ||.|.. ..| |.|    |  . |       | . .||  ..|.|.|..|.|
viestrllGytflfPv...vlPkphvre.vlLteqdellivGnkalWevlsideaveavrkeedplvaAkk.....lvdlaqsygaadsvsvlvvrl
PP2C_SIG_SM00331 717-958 9.8e-14 44.4 In-house 32-217 (217) alignment 
Range on Protein: 717-958
Range on HMM: 32-217/217.0
LFGVFDGHAGRGAADSASKLFPKEIEKLLESGnyslteqddggdnnHNQSKLLNDLFSNVDNKmKDHEYEGCTATLALIwsdgeeqqQQQQRYLQVGNVG
|. |.||. .  ||  ||. . . ...||..|              .. |..|. | . .... |. .  ..|..|||.        . ... |.. |.|
llvvaDgmGkGlaAaaassqlrtalrellseg..............eelsqalkrlnraiyee.keekgmfaTlllaly........dfssgklsyanaG

DSSAFLCRGNESIELTFDhkandpsekqrikdqgipvsdnqtringvavsrslgnhfIKEQNIGMISTPHISNRYLLTPQDKFVIIASDGLWDVIN----
||  .| | .. .| . |                                       .. . .|..... .  | |   .. ......|||... .    
dsrpyllrdgklveilkd.......................................vegaplGlepevsvdirelelekgdllllytDGltearsekgf

-GKDAIEKVSSLYdqGATADSMAS---CLLETAIQSSLCKDNVTVIIVKL
  .. .| . .|   . .|. .|.     |..... |  .|..||..||.
aeerleeiledlv..dseaqelaqkiveellelakgsngeDdiTvvvvkv
subfamily_Choan-PPM1K-like_pd Subfamily Choan-PPM1K-like 719-871 7.7e-11 35.0 In-house 25-182 (292) alignment 
Range on Protein: 719-871
Range on HMM: 25-182/292.0
GVFDGHA--GRGAADSASKLFPKEIEKLlesgnyslTEQDDGGDnNHNQSKLLnDLFSNVDNKMKDHEYEGCTATLALIWSDGeeqqqqqqRYLQVGNVG
 |.|||   |.  |. | . . .|. .|        | |      .    ..| |. ...|. . |.  .. ||.   .  |.        | | . |||
avldGhGvnGdkvaqlaedtlevellel........trqlqels.ealllril.diaakldkltidaresattavvcarvrdd........ralilanvG

DSSAFLCR-----GNESIELTFDHKANDPSEKQRIKDQGIPVSD---------NQTRI-------NGVAVSRSLGN
|| | | |      .| | |. ||| .|| |..||.  |  |             .|.        ..|.||.||.
dsrallgrclggsdyeliPlsrdhkPedPderarilraGGrveptrvrgwgfrGtarvwrrrqqeGdlalsralGd
subfamily_PDP_pd Subfamily PDP 884-942 2e-09 30.1 In-house 273-330 (398) alignment 
Range on Protein: 884-942
Range on HMM: 273-330/398.0
TPHISNrYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATADSMASCLLETAI
.| . . . |...|||...|.|||||... ..... |.  ... ........   ....
ePevts.hklrendkFLvlatDGLwdllsneevvslVgehlakkkekepvkveeakltl
subfamily_PPM1H_pd Subfamily PPM1H 706-767 9.2e-08 24.2 In-house 53-114 (404) alignment 
Range on Protein: 706-767
Range on HMM: 53-114/404.0
EKKLSNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLESGNYSLTEQDDGGDNNHNQSK
||. ..  .. .||.|||||| |||  ||||. | ... ||.    |.|...  ..| ..|.
ekseeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeeeenteess
subfamily_PPM1H_pd Subfamily PPM1H 860-931 1.4e-06 20.3 In-house 278-358 (404) alignment 
Range on Protein: 860-931
Range on HMM: 278-358/404.0
INGVAVSRSLGNHFIKEQNIGM------ISTPHISNRYLL---TPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATAD
.. ..|.| ||.| .|  . ..       ..|... . |    . .|. .|.|.||||||.. ... | |... ..  ..|
latigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskveped
PPM_PTC7_SpoIIE_motif 897-957 1.4e-06 21.9 In-house 12-79 (81) alignment 
Range on Protein: 897-957
Range on HMM: 12-79/81.0
DKFVIIASDGLWDVINGKDAI---EKVSSLYD--QGATADSMASCLLETAIQS--SLCKDNVTVIIVK
.  .....|||.. .. .. .   |.. .| |  .| .....|  |......     ..|..|.....
gdvllLyTDGltEardsdgelfgkeellrladraegkslqeladklvdevlengsgereDDitllvlr
Subfamily Dicty-PPM1L-like 861-958 1.8e-06 20.0 In-house 202-303 (305) alignment 
Range on Protein: 861-958
Range on HMM: 202-303/305.0
NG-VAVSRSLGNHFIKEQNIgmiSTPHISNRYLLTPQDKFVIIASDGLWDVINGKDAIEKVSSLYDQGATA-------DSMASCLLETAIQSSlCKDNVT
|. . .||| |.  .||  |     .      .  ..|.|...| ||||.|.. .| .|.|  |  .  .        . . .   | |..    .||.|
nrllkksrskGdknlkelvi...PnndspllvvakanDqflvlatdGlwevlsyqdvveevkellrdkssqkkiewdfneisrviveeavkrg.sgDnit

VIIVKL
..|.||
lviikl
PPM_PTC7_motif 901-951 3.1e-06 20.6 In-house 1-51 (51) alignment 
Range on Protein: 901-951
Range on HMM: 1-51/51.0
IIASDGLWDVINGKDAIEKVSSLYD-QGATADSMASCLLETAIQSSlCKDNV
|.||||||||.. ..|.. | .  . .| .  . |. | ..|..   ..||.
iLAsDGLWDvlsdqeavdlvrdqlskkglspqeaAeklvdealarg.seDni
subfamily_PP2D1_pd Subfamily PP2D1 710-763 3.8e-06 18.9 In-house 28-83 (492) alignment 
Range on Protein: 710-763
Range on HMM: 28-83/492.0
SNCSNIGLFGVFDGHAGRGAADSASKLFPKEIEKLLES--GNYSLTEQDDGGDNNH
 |  | . ||..||. |. ||. |.| ... . . ||.   ..||| . .  |||.
gndvnscFfgiyDGynGataAeiaakelhevlleelekvdervslttavnlidnnd