Gene CG16771 in Drosophila melanogaster

Synonym: Dmel\CG16771, Dmel_CG16771, CG16771

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold AP
Superfamily AP
Family AP
Subfamily AP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP004_AA protein Get Run
DmelP004_AA_107-581 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_AP_pd Subfamily AP 108-581 2.6e-181 594.1 In-house 2-469 (472) alignment 
Range on Protein: 108-581
Range on HMM: 2-469/472.0
EQKEWYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILG------VKEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNY
..| |.... .||..|...| |...|||||||.|||||..||||||||       ..||  | .|.|| .||.|||..||||||| .||||...||| |.
sakfwlkkaqeelkealelqsnskkakNvilflgdGmgvstvtaaRilkgqlkgelgeeasLaleeFpyvglsktyssdkqvpdsaatAtAylcGvktnn

ETGGVDANVPLGNCSASLkeDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGG
.| ||||.|  ..|.||   ...|..||..|. .|..||.|||||||||.||.|||||..|.||... .||||. .||.|||.||||...|....||.||
gtiGvdaaverkdCeasa..gkevdsileaAkkaGkatGlVtttrvthAsPaglyahvanRnwesdeevpaeaekegckdiaqQLieeevgkeldvilGG

GRQMLVSDVTGSAADPLDtwaGQSKDGRDLIRDWrlkkADEGVSHAVVQNNRELWNLNGQDVDYVLGIFANGHLMYDHERdrSDAGMPSLSNMTLKALEV
||...... . ..... .   |..||||.||..|    ..|  ....|.|..||.|.. ...|..||.||..|| |...|  .... |||..|| |||||
Grkkflpktvkdseyekk...gerkDgrnLieew....ekekknakyvenrkelenvdksktdrllGlfadshlkyeidr..dekeePsLkemtekAlev

LGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSsdrlDETLVIVTADHSHSLTINGHPDRGSSILGLAG-NSKTEGTPYTTLTY
| ....||.|.||.|.||.|||...|.|||.|.||...|||..|.. ..    ..||..|||||||.|||.|.|.|||||||||  .......|||||.|
LsknenGffLfVEggrIDhahhenkakkaleetlefdeavelaleltde....edTlivvtaDHshtltiagypkrgssilglakesksadelpyttlsy

--GTSYQGFQVDPQTQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRF
  |..|. .. | ....|||.|. . .|..|..|||....|. |||.||...| | .|.|..||.|||..||...||...|. 
angpgyeltesdleegerkdlteaeteakdyvsqaavpleeetHggeDvavyasGpqshlltGvveqstiahvmayaaclgea
0037220 Alkaline phosphatase-like 108-581 2.8e-141 461.6 In-house 8-471 (479) alignment 
Range on Protein: 108-581
Range on HMM: 8-471/479.0
EQKEWYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILGV------KEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNY
 .  .. . .  |  |.  ..| ..|||||||.|||||..|||||||.        .||||| ...|| .|| |||..|..|.|| ..||||. ||| |.
llllllllalallllalllllnkskaknvilfigDGmgvstvtaariylgqllgglgeegllaldkfplvglvkTysvdslvtDSAaaaTAlatGvKtnn

ETGGVDANVPLGNCSASLKedHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIeqpTGQSINVIMGG
.. ||||.|  .||...|.  ..|.|||..|.  |..||.|||||.|||||||.||||..| ||..  ... ....|| |||.||.   .|....||.||
gaigvdadvsrdncddplg..npvetilelakeaGkatGlVtTtrithATPAafyAhvanRnweddialqllgleagckdiatqlv...lgsgldvilGG

GRQML-VSDVTGSAADPLDTWAGQSKDGRDLIRDWRLKKADegvsHAVVQNNRELWNLNG-QDVDYVLGIFANGHLMYDHERdrSDAGMPSLSNMTLKAL
||...  .....   |. ... |. .|||||.  .. ||..     ..|.| .||..|.  ..||..||.||..|| |...|  . ...|||..|| |||
Grkyflpkgtldpeydlelllggkrldgrdlleeakekkkg....ytyvtnreeldaldlgsnvdkllGlfadshlpyeldr..daseePsLaemtekAl

EVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKssdrLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLT
..|...||||.|.||.| || |.|...|. ||.|||... ||| .| |.|     |.|||.|||||||...|.|..|||..||||... ...|.|||||.
dlLskndkGFfLmvEggriDhagHandaaaalgevlafdeaveaalefak....dddTlvvvtADHshgglilgyadrgnpilgllpgllldglpyttll

YGTSYQGFQVDPQtqsRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRF
|.. .. ... ..   |.|.|  ...|. ..|.|..... . |.| ||...| |... ||.||.|....||.| .|| .|..
yangpgflllldl...rldltllvtlallllqralvgwtsggHtgedVpvyayGpgaelflgvyentdiahviasalglgll
Alk_phosphatase Alkaline phosphatase 133-577 4.7e-119 388.6 Pfam-A 1-420 (421) alignment 
Range on Protein: 133-577
Range on HMM: 1-420/421.0
AKNVILFVGDGMGPNTVTAARILGVKEEGL-----LRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDanvplgncsaslKEDHHVQT
||||||..|||||. ||||||.|  ...|      |  ...| .|| |||. ||||.|| .||||.  ||| . .. |||            .....|..
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

ILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPtgQSINVIMGGGRQMLVSDVTGSAadplDTWAGQSKD
.|..|. .|  || ||||||||||||||.||| .|.|| .. ..|.|. .|. ||| |||...  . |.|..||||. ..  .|          .|  .|
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkde....ekerGtrld

GRDLIRDWrlkkadEGVSHAVVQNNRELWNLNGQD-VDYVLGIFANGHLMYDHERDrsDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGN
||.|| ..         .  .|.. .|| . . .  |...||.||.|.| .. |||  ..  |||..|| .|...|   .||| |.|| . ||.|.| ..
grnlieea......kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerd..ekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHend

ARKALSEVLELNAAVESTLSFLKsSDrlDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSK-TEGTPYTTLTYGTSYqGFQVDPqtQSRKDPTADDIT
| .|||||.|.. ||.  | | | ..  .||||.||||||| ..|.| . ||.|| |||   | ..|.... ..|| .. | .|.   ..|.. ||.. .
avgalsEvvefdeAvkaalefak.ke..ketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygnge.gakved..garenvtaeeal

AWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALR
. .| ...|.  ... |.|.||.. | | .. |..||.|| ..|. . .|| 
ekiyrkrsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaale
Alk_phosphatase Alkaline phosphatase 133-577 4.7e-119 388.6 In-house 1-420 (421) alignment 
Range on Protein: 133-577
Range on HMM: 1-420/421.0
AKNVILFVGDGMGPNTVTAARILGVKEEGL-----LRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDanvplgncsaslKEDHHVQT
||||||..|||||. ||||||.|  ...|      |  ...| .|| |||. ||||.|| .||||.  ||| . .. |||            .....|..
aknvilligDGmgvstvtaaRslkeqakgklgeeilaldrlplvglsktyavdkqvtDSaataTAyacgvktyngaigvd............thgkevks

ILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPtgQSINVIMGGGRQMLVSDVTGSAadplDTWAGQSKD
.|..|. .|  || ||||||||||||||.||| .|.|| .. ..|.|. .|. ||| |||...  . |.|..||||. ..  .|          .|  .|
vleaAkkaGkstGlVtTtrvthAtPaalvahvasRkweddaataasakkeGkkdiaeqlikak..kkidvllGGGrkeflptgtkde....ekerGtrld

GRDLIRDWrlkkadEGVSHAVVQNNRELWNLNGQD-VDYVLGIFANGHLMYDHERDrsDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGN
||.|| ..         .  .|.. .|| . . .  |...||.||.|.| .. |||  ..  |||..|| .|...|   .||| |.|| . ||.|.| ..
grnlieea......kkagyqyvsdrkeLlkakeensvkplLGLFadgdlkvelerd..ekeePsLkemtevAiklLsknekGFFLlVEGsrIDhaaHend

ARKALSEVLELNAAVESTLSFLKsSDrlDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSK-TEGTPYTTLTYGTSYqGFQVDPqtQSRKDPTADDIT
| .|||||.|.. ||.  | | | ..  .||||.||||||| ..|.| . ||.|| |||   | ..|.... ..|| .. | .|.   ..|.. ||.. .
avgalsEvvefdeAvkaalefak.ke..ketlvvvTaDHshvfsiggytqrgtsieglaaakktkdgkakklilygnge.gakved..garenvtaeeal

AWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALR
. .| ...|.  ... |.|.||.. | | .. |..||.|| ..|. . .|| 
ekiyrkrsavgltseeHtgedvavfAygpkaelvrGvqeqteiakvlaaale
Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase 366-489 6.3e-07 18.5 Pfam-A 142-267 (365) alignment 
Range on Protein: 366-489
Range on HMM: 142-267/365.0
VLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHH-RG-NARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTA
|   .||.. ..... . . . .| ... . .... |  ...  ||.|.   .|...|  | .. ..   . ..  |.. .|  |..   |..|..|...
vkdenankkgeeplsakevlesepkvdtilsdvakrlleeerpdlllvylselDsvgHkfgpdspevedalrrvDraigeLlealdergllentniilvS

DHSHSLTINGHPDRGSSILGLAGNSK
||  . ..| .  . ...|.|.|. |
DHGmadvlnkkvidlnellrlegllk
Sulfatase Sulfatase 427-478 1.9e-06 16.8 Pfam-A 210-261 (308) alignment 
Range on Protein: 427-478
Range on HMM: 210-261/308.0
ARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDRG
... |  | . . .... |  |. .  ||.|||..|.|| .||  ...| ||
leaylnsveyvDdligrvlaaLeenglldntlvvftSDhgasleesngplrg